Rank | Gene Set | Z-score |
---|---|---|
1 | DNA deamination (GO:0045006) | 9.37717655 |
2 | positive regulation of fibroblast migration (GO:0010763) | 9.17469324 |
3 | heart field specification (GO:0003128) | 9.14723846 |
4 | secondary heart field specification (GO:0003139) | 9.14723846 |
5 | cell migration involved in heart development (GO:0060973) | 9.11131341 |
6 | negative regulation of cell fate specification (GO:0009996) | 8.99517423 |
7 | cytidine deamination (GO:0009972) | 8.62709764 |
8 | cytidine metabolic process (GO:0046087) | 8.62709764 |
9 | cytidine catabolic process (GO:0006216) | 8.62709764 |
10 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 7.66751513 |
11 | growth hormone receptor signaling pathway (GO:0060396) | 7.46170396 |
12 | positive regulation of cell fate commitment (GO:0010455) | 7.31591811 |
13 | cardiac ventricle formation (GO:0003211) | 7.29394856 |
14 | positive regulation of interleukin-17 production (GO:0032740) | 6.83499374 |
15 | cardiac chamber formation (GO:0003207) | 6.68840675 |
16 | cellular response to growth hormone stimulus (GO:0071378) | 6.64259353 |
17 | negative regulation of cell fate commitment (GO:0010454) | 6.24260604 |
18 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 6.00747690 |
19 | regulation of metalloenzyme activity (GO:0048552) | 5.92131622 |
20 | specification of organ identity (GO:0010092) | 5.79226723 |
21 | regulation of mesoderm development (GO:2000380) | 5.58339744 |
22 | cell migration involved in gastrulation (GO:0042074) | 5.56401053 |
23 | sleep (GO:0030431) | 5.55471945 |
24 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 5.53683853 |
25 | positive regulation of extracellular matrix organization (GO:1903055) | 5.46694352 |
26 | T-helper 1 type immune response (GO:0042088) | 5.39159725 |
27 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 4.68608826 |
28 | positive regulation of defense response to virus by host (GO:0002230) | 4.64220913 |
29 | regulation of cell fate specification (GO:0042659) | 4.47429626 |
30 | endothelial cell differentiation (GO:0045446) | 4.36305049 |
31 | positive regulation of lamellipodium organization (GO:1902745) | 4.35568411 |
32 | somite rostral/caudal axis specification (GO:0032525) | 4.33061025 |
33 | intra-S DNA damage checkpoint (GO:0031573) | 4.30410594 |
34 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.28422048 |
35 | positive regulation of calcium-mediated signaling (GO:0050850) | 4.21854820 |
36 | regulation of fibroblast migration (GO:0010762) | 4.16566658 |
37 | cytokine biosynthetic process (GO:0042089) | 4.15439000 |
38 | positive regulation of substrate adhesion-dependent cell spreading (GO:1900026) | 4.14215462 |
39 | hydrogen peroxide biosynthetic process (GO:0050665) | 4.12921763 |
40 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 4.10278166 |
41 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 4.10278166 |
42 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 4.03349697 |
43 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 3.96581116 |
44 | regulation of interleukin-17 production (GO:0032660) | 3.92581155 |
45 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 3.92247974 |
46 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 3.86046969 |
47 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 3.86046969 |
48 | L-fucose metabolic process (GO:0042354) | 3.81804279 |
49 | L-fucose catabolic process (GO:0042355) | 3.81804279 |
50 | fucose catabolic process (GO:0019317) | 3.81804279 |
51 | positive regulation of Notch signaling pathway (GO:0045747) | 3.78382118 |
52 | respiratory system process (GO:0003016) | 3.74583074 |
53 | reactive oxygen species biosynthetic process (GO:1903409) | 3.72832002 |
54 | signal transduction involved in regulation of gene expression (GO:0023019) | 3.70299642 |
55 | negative regulation of osteoclast differentiation (GO:0045671) | 3.62812259 |
56 | response to growth hormone (GO:0060416) | 3.54685063 |
57 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.50222228 |
58 | activated T cell proliferation (GO:0050798) | 3.47099316 |
59 | cytokine metabolic process (GO:0042107) | 3.44835942 |
60 | mesodermal cell differentiation (GO:0048333) | 3.44083427 |
61 | positive regulation of activated T cell proliferation (GO:0042104) | 3.40243819 |
62 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 3.38802135 |
63 | positive regulation of natural killer cell activation (GO:0032816) | 3.32100850 |
64 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.30980079 |
65 | regulation of substrate adhesion-dependent cell spreading (GO:1900024) | 3.20547123 |
66 | regulation of calcium-mediated signaling (GO:0050848) | 3.18580275 |
67 | regulation of regulatory T cell differentiation (GO:0045589) | 3.18496144 |
68 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.17234817 |
69 | negative regulation of telomerase activity (GO:0051974) | 3.14933344 |
70 | negative regulation of embryonic development (GO:0045992) | 3.09020746 |
71 | Golgi transport vesicle coating (GO:0048200) | 3.08455679 |
72 | COPI coating of Golgi vesicle (GO:0048205) | 3.08455679 |
73 | positive regulation of mRNA catabolic process (GO:0061014) | 3.07287586 |
74 | positive regulation of mRNA 3-end processing (GO:0031442) | 3.06066599 |
75 | positive regulation of establishment of protein localization to plasma membrane (GO:0090004) | 3.05299117 |
76 | purinergic nucleotide receptor signaling pathway (GO:0035590) | 3.04453863 |
77 | DNA replication checkpoint (GO:0000076) | 3.03980344 |
78 | response to nerve growth factor (GO:1990089) | 3.03296015 |
79 | cellular response to nerve growth factor stimulus (GO:1990090) | 3.03296015 |
80 | positive regulation of striated muscle cell differentiation (GO:0051155) | 3.00851089 |
81 | negative regulation of viral genome replication (GO:0045071) | 2.98930160 |
82 | adaptation of signaling pathway (GO:0023058) | 2.98469277 |
83 | regulation of telomere maintenance via telomerase (GO:0032210) | 2.92996639 |
84 | positive regulation of protein localization to plasma membrane (GO:1903078) | 2.92914003 |
85 | cardiac chamber morphogenesis (GO:0003206) | 2.91922178 |
86 | tolerance induction (GO:0002507) | 2.91907757 |
87 | filopodium assembly (GO:0046847) | 2.91845869 |
88 | regulation of extracellular matrix organization (GO:1903053) | 2.90374880 |
89 | positive regulation of NF-kappaB import into nucleus (GO:0042346) | 2.88805919 |
90 | positive regulation of B cell differentiation (GO:0045579) | 2.86734253 |
91 | cellular response to interleukin-15 (GO:0071350) | 2.86570967 |
92 | DNA demethylation (GO:0080111) | 2.83441035 |
93 | leukocyte aggregation (GO:0070486) | 2.82559119 |
94 | defense response to fungus (GO:0050832) | 2.81921770 |
95 | alkaloid metabolic process (GO:0009820) | 2.81192653 |
96 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.80432017 |
97 | regulation of natural killer cell activation (GO:0032814) | 2.77916594 |
98 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 2.77282219 |
99 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 10.3682473 |
100 | regulation of Wnt signaling pathway involved in heart development (GO:0003307) | 10.3671223 |
Rank | Gene Set | Z-score |
---|---|---|
1 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 9.98580094 |
2 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 5.34812122 |
3 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.22731085 |
4 | * STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.40851183 |
5 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 4.02396488 |
6 | * RUNX_20019798_ChIP-Seq_JUKART_Human | 3.59760933 |
7 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 3.13788170 |
8 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.09496462 |
9 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.03547564 |
10 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.61159702 |
11 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.45004138 |
12 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.30008650 |
13 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.16973757 |
14 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.06601217 |
15 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.94165709 |
16 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.93314415 |
17 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.92480556 |
18 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.87324705 |
19 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.84712370 |
20 | * CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.82009958 |
21 | MYB_26560356_Chip-Seq_TH2_Human | 1.78341046 |
22 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.77497207 |
23 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.72129856 |
24 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.69199133 |
25 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.68507515 |
26 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.65957339 |
27 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.57298475 |
28 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.56456310 |
29 | GATA3_26560356_Chip-Seq_TH2_Human | 1.53340338 |
30 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.51505125 |
31 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.42730468 |
32 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.38580243 |
33 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.37328218 |
34 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 1.35450776 |
35 | * TAF2_19829295_ChIP-Seq_ESCs_Human | 1.34790703 |
36 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.33385103 |
37 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.27821730 |
38 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.27145303 |
39 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.26671169 |
40 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.25787481 |
41 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.22327955 |
42 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.18308002 |
43 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.12160516 |
44 | * GATA3_26560356_Chip-Seq_TH1_Human | 1.11676039 |
45 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.08523383 |
46 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.06237370 |
47 | * RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.05576043 |
48 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.05381087 |
49 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.04328953 |
50 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.00446100 |
51 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.98217631 |
52 | * GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.96436054 |
53 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.94328032 |
54 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 0.94064079 |
55 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.93238456 |
56 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.92215247 |
57 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.92141970 |
58 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.91885733 |
59 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.91157866 |
60 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.90426082 |
61 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.89986992 |
62 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.88912241 |
63 | * MYB_26560356_Chip-Seq_TH1_Human | 0.88842885 |
64 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.87882933 |
65 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 0.87466013 |
66 | * BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.86089493 |
67 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 0.86052082 |
68 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 0.85411966 |
69 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.84964041 |
70 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.83548216 |
71 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.83503498 |
72 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.80594199 |
73 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.79926430 |
74 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.79538513 |
75 | SA1_27219007_Chip-Seq_Bcells_Human | 0.78811615 |
76 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.78506998 |
77 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.78009864 |
78 | * GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.77827070 |
79 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.77482824 |
80 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.77342821 |
81 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.76768397 |
82 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.76741257 |
83 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.76074360 |
84 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.75406771 |
85 | CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.75355754 |
86 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.75315140 |
87 | KDM2B_26808549_Chip-Seq_REH_Human | 0.74608247 |
88 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.73424339 |
89 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.73316268 |
90 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.73093757 |
91 | * CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.73068991 |
92 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.71762308 |
93 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 0.71342702 |
94 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.71258630 |
95 | * RBPJ_21746931_ChIP-Seq_IB4_Human | 0.70882342 |
96 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.70712122 |
97 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.70700006 |
98 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.69991151 |
99 | VDR_22108803_ChIP-Seq_LS180_Human | 0.69615463 |
100 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.69493218 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002234_abnormal_pharynx_morphology | 8.38167457 |
2 | MP0001873_stomach_inflammation | 7.57969305 |
3 | MP0006082_CNS_inflammation | 5.31383790 |
4 | MP0000465_gastrointestinal_hemorrhage | 3.91558229 |
5 | MP0004510_myositis | 3.50802907 |
6 | MP0005671_abnormal_response_to | 3.48884390 |
7 | MP0004130_abnormal_muscle_cell | 2.84270632 |
8 | MP0001835_abnormal_antigen_presentation | 2.76184122 |
9 | MP0001851_eye_inflammation | 2.53134621 |
10 | MP0002933_joint_inflammation | 2.52102247 |
11 | MP0001800_abnormal_humoral_immune | 2.31663087 |
12 | MP0005360_urolithiasis | 2.27402867 |
13 | MP0003763_abnormal_thymus_physiology | 2.26304897 |
14 | MP0003436_decreased_susceptibility_to | 2.21177277 |
15 | MP0005025_abnormal_response_to | 2.19347898 |
16 | MP0005000_abnormal_immune_tolerance | 2.09462294 |
17 | MP0002148_abnormal_hypersensitivity_rea | 1.92658158 |
18 | MP0008875_abnormal_xenobiotic_pharmacok | 1.91755947 |
19 | MP0004782_abnormal_surfactant_physiolog | 1.83158569 |
20 | MP0009785_altered_susceptibility_to | 1.81550726 |
21 | MP0002419_abnormal_innate_immunity | 1.78754073 |
22 | MP0002723_abnormal_immune_serum | 1.77048531 |
23 | MP0002452_abnormal_antigen_presenting | 1.73027903 |
24 | MP0001663_abnormal_digestive_system | 1.69405227 |
25 | MP0001790_abnormal_immune_system | 1.65957068 |
26 | MP0005387_immune_system_phenotype | 1.65957068 |
27 | MP0002420_abnormal_adaptive_immunity | 1.65712771 |
28 | MP0009333_abnormal_splenocyte_physiolog | 1.65037385 |
29 | MP0003646_muscle_fatigue | 1.59993493 |
30 | MP0001819_abnormal_immune_cell | 1.59541245 |
31 | MP0005666_abnormal_adipose_tissue | 1.58765385 |
32 | MP0008872_abnormal_physiological_respon | 1.50352462 |
33 | MP0005166_decreased_susceptibility_to | 1.50325092 |
34 | MP0003724_increased_susceptibility_to | 1.42648047 |
35 | MP0001845_abnormal_inflammatory_respons | 1.41775626 |
36 | MP0002405_respiratory_system_inflammati | 1.39387708 |
37 | MP0003075_altered_response_to | 1.33012402 |
38 | MP0008469_abnormal_protein_level | 1.27204398 |
39 | MP0004947_skin_inflammation | 1.26871823 |
40 | MP0000716_abnormal_immune_system | 1.26247681 |
41 | MP0000703_abnormal_thymus_morphology | 1.25783077 |
42 | MP0005381_digestive/alimentary_phenotyp | 1.25674800 |
43 | MP0010155_abnormal_intestine_physiology | 1.23056049 |
44 | MP0000685_abnormal_immune_system | 1.19830444 |
45 | MP0002398_abnormal_bone_marrow | 1.16961187 |
46 | MP0001533_abnormal_skeleton_physiology | 1.11125974 |
47 | MP0002722_abnormal_immune_system | 1.10643263 |
48 | MP0003300_gastrointestinal_ulcer | 1.10034842 |
49 | MP0002177_abnormal_outer_ear | 1.05181874 |
50 | MP0005334_abnormal_fat_pad | 0.99927602 |
51 | MP0003866_abnormal_defecation | 0.99887958 |
52 | MP0002693_abnormal_pancreas_physiology | 0.98268848 |
53 | MP0008873_increased_physiological_sensi | 0.97946515 |
54 | MP0000569_abnormal_digit_pigmentation | 0.95552987 |
55 | MP0000689_abnormal_spleen_morphology | 0.94538242 |
56 | MP0003011_delayed_dark_adaptation | 0.92662583 |
57 | MP0002429_abnormal_blood_cell | 0.89186632 |
58 | MP0001664_abnormal_digestion | 0.87794357 |
59 | MP0002277_abnormal_respiratory_mucosa | 0.87402462 |
60 | MP0004381_abnormal_hair_follicle | 0.86858628 |
61 | MP0000343_altered_response_to | 0.82607875 |
62 | MP0001529_abnormal_vocalization | 0.78631618 |
63 | MP0005310_abnormal_salivary_gland | 0.78510896 |
64 | MP0009764_decreased_sensitivity_to | 0.76211412 |
65 | MP0002932_abnormal_joint_morphology | 0.72431383 |
66 | MP0004264_abnormal_extraembryonic_tissu | 0.70199005 |
67 | MP0001905_abnormal_dopamine_level | 0.68331683 |
68 | MP0004142_abnormal_muscle_tone | 0.67920485 |
69 | MP0005375_adipose_tissue_phenotype | 0.67137095 |
70 | MP0009384_cardiac_valve_regurgitation | 0.66629133 |
71 | MP0001348_abnormal_lacrimal_gland | 0.65560908 |
72 | MP0009115_abnormal_fat_cell | 0.65327340 |
73 | MP0003638_abnormal_response/metabolism_ | 0.64918618 |
74 | MP0005448_abnormal_energy_balance | 0.63594953 |
75 | MP0001853_heart_inflammation | 0.59461717 |
76 | MP0002089_abnormal_postnatal_growth/wei | 0.58275905 |
77 | MP0008569_lethality_at_weaning | 0.57963747 |
78 | MP0000627_abnormal_mammary_gland | 0.57357226 |
79 | MP0005464_abnormal_platelet_physiology | 0.56724307 |
80 | MP0005253_abnormal_eye_physiology | 0.56419459 |
81 | MP0003448_altered_tumor_morphology | 0.56215932 |
82 | MP0009763_increased_sensitivity_to | 0.56213976 |
83 | MP0002163_abnormal_gland_morphology | 0.54418549 |
84 | MP0000372_irregular_coat_pigmentation | 0.53206652 |
85 | MP0008932_abnormal_embryonic_tissue | 0.52897167 |
86 | MP0002132_abnormal_respiratory_system | 0.52542498 |
87 | MP0003195_calcinosis | 0.52335356 |
88 | MP0003950_abnormal_plasma_membrane | 0.52292891 |
89 | MP0001727_abnormal_embryo_implantation | 0.52167127 |
90 | MP0000230_abnormal_systemic_arterial | 0.51174850 |
91 | MP0002998_abnormal_bone_remodeling | 0.50019577 |
92 | MP0003936_abnormal_reproductive_system | 0.49112820 |
93 | MP0002166_altered_tumor_susceptibility | 0.48682485 |
94 | MP0003567_abnormal_fetal_cardiomyocyte | 0.48012355 |
95 | MP0003045_fibrosis | 0.47948836 |
96 | MP0005386_behavior/neurological_phenoty | 0.47516633 |
97 | MP0004924_abnormal_behavior | 0.47516633 |
98 | MP0001765_abnormal_ion_homeostasis | 0.46122999 |
99 | MP0010307_abnormal_tumor_latency | 0.43836000 |
100 | MP0008877_abnormal_DNA_methylation | 0.42535516 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Birth length less than 3rd percentile (HP:0003561) | 8.66573452 |
2 | Neonatal hypoglycemia (HP:0001998) | 8.31455237 |
3 | Lip pit (HP:0100267) | 7.62821002 |
4 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 6.97684188 |
5 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 6.97684188 |
6 | Chin dimple (HP:0010751) | 6.91812822 |
7 | Enlarged epiphyses (HP:0010580) | 6.89134291 |
8 | Anterior segment dysgenesis (HP:0007700) | 6.35503406 |
9 | Sparse lateral eyebrow (HP:0005338) | 6.34062717 |
10 | Depressed nasal tip (HP:0000437) | 6.28568877 |
11 | Glucose intolerance (HP:0000833) | 6.21836368 |
12 | Abnormality of the fingertips (HP:0001211) | 5.48195074 |
13 | Myotonia (HP:0002486) | 5.41555267 |
14 | Premature skin wrinkling (HP:0100678) | 5.34655343 |
15 | Agammaglobulinemia (HP:0004432) | 5.23490625 |
16 | Insulin-resistant diabetes mellitus (HP:0000831) | 4.86325841 |
17 | Hypoplasia of the iris (HP:0007676) | 4.75628330 |
18 | Abnormality of the columella (HP:0009929) | 4.73095136 |
19 | Abnormal glucose tolerance (HP:0001952) | 4.25675474 |
20 | Stomatitis (HP:0010280) | 4.12960702 |
21 | Epileptic encephalopathy (HP:0200134) | 4.12757434 |
22 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.01573959 |
23 | Fatigable weakness (HP:0003473) | 3.77430424 |
24 | Abnormality of the neuromuscular junction (HP:0003398) | 3.77430424 |
25 | Hyperglycemia (HP:0003074) | 3.70337179 |
26 | Ectropion (HP:0000656) | 3.64031612 |
27 | Meningitis (HP:0001287) | 3.31086717 |
28 | Cellulitis (HP:0100658) | 3.16907326 |
29 | T lymphocytopenia (HP:0005403) | 3.12203960 |
30 | Easy fatigability (HP:0003388) | 3.09951842 |
31 | * Abnormality of T cell number (HP:0011839) | 2.93479180 |
32 | Recurrent abscess formation (HP:0002722) | 2.79269988 |
33 | Mask-like facies (HP:0000298) | 2.78118666 |
34 | Long palpebral fissure (HP:0000637) | 2.76384490 |
35 | Hypoproteinemia (HP:0003075) | 2.71932641 |
36 | Prominent supraorbital ridges (HP:0000336) | 2.60030684 |
37 | Alveolar cell carcinoma (HP:0006519) | 2.56699426 |
38 | Periodontitis (HP:0000704) | 2.54737019 |
39 | Type 2 muscle fiber atrophy (HP:0003554) | 2.49410579 |
40 | Verrucae (HP:0200043) | 2.44711672 |
41 | Papilloma (HP:0012740) | 2.44711672 |
42 | Hemiplegia (HP:0002301) | 2.41474141 |
43 | Abnormality of the anterior chamber (HP:0000593) | 2.39975162 |
44 | Cerebellar dysplasia (HP:0007033) | 2.34901445 |
45 | Abnormality of the pupil (HP:0000615) | 2.32324486 |
46 | Muscle fiber atrophy (HP:0100295) | 2.31650353 |
47 | Megalocornea (HP:0000485) | 2.31579237 |
48 | Abnormality of binocular vision (HP:0011514) | 2.29915682 |
49 | Diplopia (HP:0000651) | 2.29915682 |
50 | Gingivitis (HP:0000230) | 2.27976337 |
51 | Cupped ear (HP:0000378) | 2.27421526 |
52 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.24450060 |
53 | Encephalitis (HP:0002383) | 2.18205223 |
54 | Optic neuritis (HP:0100653) | 2.16180220 |
55 | Retrobulbar optic neuritis (HP:0100654) | 2.16180220 |
56 | Chronic diarrhea (HP:0002028) | 2.15484227 |
57 | * Abnormality of T cells (HP:0002843) | 2.13009007 |
58 | Skin pits (HP:0100276) | 2.12909385 |
59 | Myositis (HP:0100614) | 2.11937418 |
60 | Insulin resistance (HP:0000855) | 2.11530344 |
61 | IgG deficiency (HP:0004315) | 2.05656562 |
62 | Osteomyelitis (HP:0002754) | 2.02131734 |
63 | * Leukocytosis (HP:0001974) | 2.01745278 |
64 | Hypodontia (HP:0000668) | 1.99619097 |
65 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.96736628 |
66 | Coarctation of aorta (HP:0001680) | 1.96716611 |
67 | Sepsis (HP:0100806) | 1.95947679 |
68 | Abnormality of macrophages (HP:0004311) | 1.93666426 |
69 | Adactyly (HP:0009776) | 1.87959156 |
70 | Nonprogressive disorder (HP:0003680) | 1.85089353 |
71 | Eczematoid dermatitis (HP:0000976) | 1.84716571 |
72 | Orchitis (HP:0100796) | 1.84077272 |
73 | Abnormality of the renal collecting system (HP:0004742) | 1.83341898 |
74 | Skin rash (HP:0000988) | 1.82671546 |
75 | Duplicated collecting system (HP:0000081) | 1.82108292 |
76 | Ureteral stenosis (HP:0000071) | 1.81235991 |
77 | Constricted visual fields (HP:0001133) | 1.75114916 |
78 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.73896683 |
79 | Pulmonary infiltrates (HP:0002113) | 1.72783499 |
80 | Non-midline cleft lip (HP:0100335) | 1.72725130 |
81 | Death in infancy (HP:0001522) | 1.69409689 |
82 | Broad nasal tip (HP:0000455) | 1.68488695 |
83 | Mediastinal lymphadenopathy (HP:0100721) | 1.68246193 |
84 | Dental malocclusion (HP:0000689) | 1.67356907 |
85 | Microdontia (HP:0000691) | 1.67153477 |
86 | Preauricular skin tag (HP:0000384) | 1.66353392 |
87 | Severe combined immunodeficiency (HP:0004430) | 1.66175797 |
88 | Long eyelashes (HP:0000527) | 1.65685341 |
89 | Ureteral obstruction (HP:0006000) | 1.64279334 |
90 | * Neutropenia (HP:0001875) | 1.63259026 |
91 | Hypoalbuminemia (HP:0003073) | 1.62642881 |
92 | Abnormal albumin level (HP:0012116) | 1.62642881 |
93 | Pulmonary embolism (HP:0002204) | 1.61775746 |
94 | Posterior embryotoxon (HP:0000627) | 1.60951878 |
95 | Abnormality of the line of Schwalbe (HP:0008048) | 1.58261289 |
96 | Neck muscle weakness (HP:0000467) | 1.57050900 |
97 | Oligodontia (HP:0000677) | 1.54024289 |
98 | Striae distensae (HP:0001065) | 1.52958654 |
99 | Chronic obstructive pulmonary disease (HP:0006510) | 1.51867394 |
100 | Obstructive lung disease (HP:0006536) | 1.51867394 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PIK3CA | 7.71766576 |
2 | CDK19 | 3.73035847 |
3 | MAP3K6 | 2.59457430 |
4 | CAMK1D | 2.40795158 |
5 | RET | 2.38187003 |
6 | BMPR2 | 2.35267803 |
7 | CAMKK2 | 2.23833035 |
8 | TXK | 2.23538048 |
9 | OXSR1 | 2.20861376 |
10 | KIT | 2.20373769 |
11 | TLK1 | 10.4476149 |
12 | GRK7 | 1.95526036 |
13 | MAP2K3 | 1.94587232 |
14 | MAP2K6 | 1.79744901 |
15 | MAPK12 | 1.62581750 |
16 | TGFBR2 | 1.61324658 |
17 | PDGFRB | 1.48996322 |
18 | CAMK1G | 1.48718861 |
19 | MOS | 1.43254022 |
20 | STK10 | 1.39773575 |
21 | PTK2 | 1.25420216 |
22 | ZAP70 | 1.23852048 |
23 | LCK | 1.16713055 |
24 | GRK6 | 1.14459369 |
25 | MAP4K1 | 1.12091457 |
26 | PRKCG | 1.03484607 |
27 | GRK5 | 0.90524716 |
28 | CSK | 0.89234609 |
29 | PRKCH | 0.88943533 |
30 | MAP2K4 | 0.88415807 |
31 | FES | 0.85205462 |
32 | JAK3 | 0.84599314 |
33 | ITK | 0.84536155 |
34 | KDR | 0.83083705 |
35 | ADRBK2 | 0.80139569 |
36 | MAP3K11 | 0.79958693 |
37 | MARK3 | 0.74382728 |
38 | TAOK3 | 0.72613336 |
39 | SYK | 0.71530574 |
40 | CAMKK1 | 0.70698850 |
41 | ADRBK1 | 0.70106396 |
42 | IKBKB | 0.61630714 |
43 | JAK2 | 0.61320213 |
44 | MUSK | 0.57991700 |
45 | BTK | 0.57240024 |
46 | TESK1 | 0.56411696 |
47 | INSR | 0.53227883 |
48 | MAP3K5 | 0.50192091 |
49 | STK11 | 0.49625284 |
50 | PRKCQ | 0.46512903 |
51 | TNK2 | 0.45935648 |
52 | IGF1R | 0.45427425 |
53 | MINK1 | 0.43611589 |
54 | PRKD1 | 0.40053221 |
55 | FYN | 0.39412604 |
56 | PBK | 0.39058299 |
57 | PDK1 | 0.37600067 |
58 | MST4 | 0.31593738 |
59 | CAMK1 | 0.30681235 |
60 | PAK1 | 0.30508756 |
61 | PRKG1 | 0.29326633 |
62 | MATK | 0.28673535 |
63 | LYN | 0.26491347 |
64 | HCK | 0.25294037 |
65 | TESK2 | 0.22327172 |
66 | MAP4K2 | 0.22071425 |
67 | TEC | 0.21933683 |
68 | TYK2 | 0.21504881 |
69 | CAMK2A | 0.20750950 |
70 | IKBKE | 0.19511644 |
71 | CAMK4 | 0.19193024 |
72 | EPHA3 | 0.18888613 |
73 | EIF2AK2 | 0.17737136 |
74 | CSNK1D | 0.17724837 |
75 | INSRR | 0.16144843 |
76 | TYRO3 | 0.15591016 |
77 | RIPK4 | 0.12786181 |
78 | PRKACA | 0.12761437 |
79 | PRKCA | 0.11367941 |
80 | LIMK1 | 0.10744283 |
81 | JAK1 | 0.10652971 |
82 | GRK1 | 0.09501683 |
83 | PRKCD | 0.09301379 |
84 | FRK | 0.08898975 |
85 | FGR | 0.08555846 |
86 | BLK | 0.07435353 |
87 | OBSCN | 0.05896181 |
88 | EGFR | 0.05538513 |
89 | SGK3 | 0.04995645 |
90 | WNK4 | 0.04917864 |
91 | ERBB2 | 0.04876000 |
92 | FGFR1 | 0.04793758 |
93 | PIM1 | 0.04617810 |
94 | PRKCB | 0.03813304 |
95 | MAPKAPK2 | 0.03409143 |
96 | SRC | 0.02934845 |
97 | CSNK2A2 | 0.01741730 |
98 | WNK3 | 0.01377902 |
99 | ABL1 | 0.01158121 |
100 | DAPK1 | 0.00257814 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Caffeine metabolism_Homo sapiens_hsa00232 | 6.00055198 |
2 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 4.38458019 |
3 | * Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 3.06353095 |
4 | * Graft-versus-host disease_Homo sapiens_hsa05332 | 2.69051010 |
5 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.64310542 |
6 | Malaria_Homo sapiens_hsa05144 | 2.61338515 |
7 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 2.31339814 |
8 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.30947997 |
9 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.29362700 |
10 | * Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.28729203 |
11 | * Allograft rejection_Homo sapiens_hsa05330 | 2.23496939 |
12 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.17553475 |
13 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.12345811 |
14 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 2.04682451 |
15 | * Measles_Homo sapiens_hsa05162 | 1.88087488 |
16 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.76198874 |
17 | * African trypanosomiasis_Homo sapiens_hsa05143 | 1.72516465 |
18 | Legionellosis_Homo sapiens_hsa05134 | 1.66781368 |
19 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.65402639 |
20 | * Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.60478501 |
21 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.59043065 |
22 | Viral myocarditis_Homo sapiens_hsa05416 | 1.51840118 |
23 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.42103096 |
24 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.40897934 |
25 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.39526048 |
26 | * Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.29054407 |
27 | RNA polymerase_Homo sapiens_hsa03020 | 1.28118049 |
28 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.27162789 |
29 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.25951309 |
30 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.25682845 |
31 | Leishmaniasis_Homo sapiens_hsa05140 | 1.24135297 |
32 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.15705809 |
33 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.15589665 |
34 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.13624806 |
35 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.09959659 |
36 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.09752479 |
37 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.09033476 |
38 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.07302292 |
39 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.04535536 |
40 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.98168657 |
41 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.95842165 |
42 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.94782909 |
43 | * Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.94467693 |
44 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.94248499 |
45 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.90632113 |
46 | * Influenza A_Homo sapiens_hsa05164 | 0.90206482 |
47 | Pertussis_Homo sapiens_hsa05133 | 0.88435192 |
48 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.84357574 |
49 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.82562576 |
50 | Amoebiasis_Homo sapiens_hsa05146 | 0.81468256 |
51 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.80714775 |
52 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.80648574 |
53 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.80596018 |
54 | Asthma_Homo sapiens_hsa05310 | 0.80247326 |
55 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.79948535 |
56 | Salmonella infection_Homo sapiens_hsa05132 | 0.78434447 |
57 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.77894961 |
58 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.76398665 |
59 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.72781820 |
60 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.70318824 |
61 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.69966294 |
62 | Platelet activation_Homo sapiens_hsa04611 | 0.68772379 |
63 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.66934391 |
64 | Insulin resistance_Homo sapiens_hsa04931 | 0.63728937 |
65 | Tuberculosis_Homo sapiens_hsa05152 | 0.61283240 |
66 | * Apoptosis_Homo sapiens_hsa04210 | 0.59364944 |
67 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.51748941 |
68 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.48296885 |
69 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.44266696 |
70 | Colorectal cancer_Homo sapiens_hsa05210 | 0.44158167 |
71 | Hepatitis C_Homo sapiens_hsa05160 | 0.43782699 |
72 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.42931121 |
73 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.42886643 |
74 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.42572048 |
75 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.40799621 |
76 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.39677716 |
77 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.39351274 |
78 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.38911783 |
79 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.38471158 |
80 | Retinol metabolism_Homo sapiens_hsa00830 | 0.37248751 |
81 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.37143315 |
82 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.36562190 |
83 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.36021423 |
84 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.34757270 |
85 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.31023819 |
86 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.29109927 |
87 | Melanoma_Homo sapiens_hsa05218 | 0.28481073 |
88 | Endometrial cancer_Homo sapiens_hsa05213 | 0.28362687 |
89 | Glioma_Homo sapiens_hsa05214 | 0.26394665 |
90 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.24910344 |
91 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.24030925 |
92 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.23314706 |
93 | * FoxO signaling pathway_Homo sapiens_hsa04068 | 0.22882122 |
94 | HTLV-I infection_Homo sapiens_hsa05166 | 0.21287252 |
95 | * Hepatitis B_Homo sapiens_hsa05161 | 0.21215931 |
96 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.20603606 |
97 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.19626743 |
98 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.19377847 |
99 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.18979057 |
100 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.18898512 |