FASTKD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)5.49542478
2L-phenylalanine catabolic process (GO:0006559)5.49542478
3aromatic amino acid family catabolic process (GO:0009074)5.35834330
4indole-containing compound catabolic process (GO:0042436)5.28868582
5indolalkylamine catabolic process (GO:0046218)5.28868582
6tryptophan catabolic process (GO:0006569)5.28868582
7L-phenylalanine metabolic process (GO:0006558)5.27935051
8erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)5.27935051
9kynurenine metabolic process (GO:0070189)5.16542230
10serine family amino acid catabolic process (GO:0009071)5.14690406
11tryptophan metabolic process (GO:0006568)5.06769376
12urea cycle (GO:0000050)5.05326077
13urea metabolic process (GO:0019627)5.05326077
14lysine metabolic process (GO:0006553)4.91228946
15lysine catabolic process (GO:0006554)4.91228946
16glycine metabolic process (GO:0006544)4.81901680
17homocysteine metabolic process (GO:0050667)4.54094377
18nitrogen cycle metabolic process (GO:0071941)4.54036701
19glyoxylate metabolic process (GO:0046487)4.48256793
20nuclear pore complex assembly (GO:0051292)4.47167348
21amino-acid betaine metabolic process (GO:0006577)4.41561386
22triglyceride-rich lipoprotein particle remodeling (GO:0034370)4.37937109
23cysteine metabolic process (GO:0006534)4.36286697
24nuclear pore organization (GO:0006999)4.34692609
25bile acid biosynthetic process (GO:0006699)4.25439549
26IMP biosynthetic process (GO:0006188)4.25277507
27chromatin remodeling at centromere (GO:0031055)4.22160621
28serine family amino acid metabolic process (GO:0009069)4.17269810
29proteasome assembly (GO:0043248)4.17261877
30CENP-A containing nucleosome assembly (GO:0034080)4.16850677
31complement activation, alternative pathway (GO:0006957)4.08767439
32serine family amino acid biosynthetic process (GO:0009070)4.05660258
33sulfur amino acid catabolic process (GO:0000098)4.03603256
34alpha-amino acid catabolic process (GO:1901606)4.03335969
35telomere maintenance via semi-conservative replication (GO:0032201)3.99655009
36aromatic amino acid family metabolic process (GO:0009072)3.96341893
37synapsis (GO:0007129)3.95832107
38DNA replication checkpoint (GO:0000076)3.94732799
39fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.93733336
40regulation of protein activation cascade (GO:2000257)3.91636592
41DNA double-strand break processing (GO:0000729)3.89619997
42alpha-linolenic acid metabolic process (GO:0036109)3.89384045
43IMP metabolic process (GO:0046040)3.87428812
44DNA strand elongation involved in DNA replication (GO:0006271)3.83718298
45imidazole-containing compound metabolic process (GO:0052803)3.78861314
46indolalkylamine metabolic process (GO:0006586)3.78521692
47high-density lipoprotein particle remodeling (GO:0034375)3.77819559
48bile acid metabolic process (GO:0008206)3.75373465
492-oxoglutarate metabolic process (GO:0006103)3.73719724
50negative regulation of fatty acid biosynthetic process (GO:0045717)3.70893954
51cellular ketone body metabolic process (GO:0046950)3.69258846
52telomere maintenance via recombination (GO:0000722)3.69229270
53regulation of complement activation (GO:0030449)3.66251053
54somatic hypermutation of immunoglobulin genes (GO:0016446)3.65210299
55somatic diversification of immune receptors via somatic mutation (GO:0002566)3.65210299
56coenzyme catabolic process (GO:0009109)3.64910482
57cellular amino acid catabolic process (GO:0009063)3.63576022
58DNA strand elongation (GO:0022616)3.62825540
59peptidyl-glutamic acid carboxylation (GO:0017187)3.62810788
60protein carboxylation (GO:0018214)3.62810788
61ribosome assembly (GO:0042255)3.62642599
62regulation of triglyceride catabolic process (GO:0010896)3.58710177
63amine catabolic process (GO:0009310)3.58623424
64cellular biogenic amine catabolic process (GO:0042402)3.58623424
65carnitine metabolic process (GO:0009437)3.58368913
66mitotic recombination (GO:0006312)3.57114454
67oxidative phosphorylation (GO:0006119)3.56515167
68negative regulation of fibrinolysis (GO:0051918)3.53270560
69histone exchange (GO:0043486)3.52076614
70triglyceride homeostasis (GO:0070328)3.51974416
71acylglycerol homeostasis (GO:0055090)3.51974416
72valine metabolic process (GO:0006573)3.48734071
73benzene-containing compound metabolic process (GO:0042537)3.48097077
74regulation of fibrinolysis (GO:0051917)3.46930008
75positive regulation of histone H3-K4 methylation (GO:0051571)3.46411459
76one-carbon metabolic process (GO:0006730)3.46065974
77folic acid metabolic process (GO:0046655)3.44877874
78drug catabolic process (GO:0042737)3.44703425
79regulation of mitotic spindle checkpoint (GO:1903504)3.44677685
80regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.44677685
81purine nucleobase biosynthetic process (GO:0009113)3.44488240
82DNA replication initiation (GO:0006270)3.42874287
83tyrosine metabolic process (GO:0006570)3.41651623
84bile acid and bile salt transport (GO:0015721)3.40085663
85kinetochore organization (GO:0051383)3.37656070
86DNA replication-independent nucleosome assembly (GO:0006336)3.37302430
87DNA replication-independent nucleosome organization (GO:0034724)3.37302430
88protein localization to kinetochore (GO:0034501)3.35373900
89pore complex assembly (GO:0046931)3.34984957
90fatty acid beta-oxidation (GO:0006635)3.34536147
91negative regulation of sister chromatid segregation (GO:0033046)3.34081097
92negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.34081097
93negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.34081097
94negative regulation of mitotic sister chromatid segregation (GO:0033048)3.34081097
95negative regulation of mitotic sister chromatid separation (GO:2000816)3.34081097
96double-strand break repair via nonhomologous end joining (GO:0006303)3.33220138
97non-recombinational repair (GO:0000726)3.33220138
98mitotic nuclear envelope disassembly (GO:0007077)3.32888682
99pyridine nucleotide biosynthetic process (GO:0019363)3.32759295
100nicotinamide nucleotide biosynthetic process (GO:0019359)3.32759295
101aspartate family amino acid catabolic process (GO:0009068)3.32561502
102NAD biosynthetic process (GO:0009435)3.32062006
103plasma lipoprotein particle remodeling (GO:0034369)3.31940968
104protein-lipid complex remodeling (GO:0034368)3.31940968
105macromolecular complex remodeling (GO:0034367)3.31940968
106nucleotide-excision repair, DNA gap filling (GO:0006297)3.30208437
107negative regulation of DNA-dependent DNA replication (GO:2000104)3.30169192
108formation of translation preinitiation complex (GO:0001731)3.29387542
109dicarboxylic acid biosynthetic process (GO:0043650)3.27991679
110DNA replication-dependent nucleosome organization (GO:0034723)3.27885268
111DNA replication-dependent nucleosome assembly (GO:0006335)3.27885268
112acetyl-CoA metabolic process (GO:0006084)3.27729444
113negative regulation of chromosome segregation (GO:0051985)3.27654402
114mitotic spindle checkpoint (GO:0071174)3.26748398
115replication fork processing (GO:0031297)3.25110373
116cellular glucuronidation (GO:0052695)3.25005882
117regulation of cholesterol esterification (GO:0010872)3.24944394
118rRNA modification (GO:0000154)3.24568081
119carboxylic acid catabolic process (GO:0046395)3.24558532
120organic acid catabolic process (GO:0016054)3.24558532
121regulation of mitotic metaphase/anaphase transition (GO:0030071)3.22937927
122regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.22937927
123amino acid activation (GO:0043038)3.22430841
124tRNA aminoacylation (GO:0043039)3.22430841
125tRNA aminoacylation for protein translation (GO:0006418)3.21227235
126fatty acid oxidation (GO:0019395)3.21050558
127spindle checkpoint (GO:0031577)3.20174211
128fatty acid transmembrane transport (GO:1902001)3.19901623
129branched-chain amino acid catabolic process (GO:0009083)3.19744747
130metaphase plate congression (GO:0051310)3.19345380
131telomere maintenance via telomere lengthening (GO:0010833)3.19118125
132postreplication repair (GO:0006301)3.17517110
133tricarboxylic acid cycle (GO:0006099)3.17248944
134NAD metabolic process (GO:0019674)3.17100051
135regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.16695063
136maturation of 5.8S rRNA (GO:0000460)3.16393556
137L-serine metabolic process (GO:0006563)3.16220434
138negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.16152325
139regulation of mitotic sister chromatid separation (GO:0010965)3.15711856
140regulation of mitotic sister chromatid segregation (GO:0033047)3.15711856
141regulation of sister chromatid segregation (GO:0033045)3.15711856
142urate metabolic process (GO:0046415)3.15257038
143ethanol oxidation (GO:0006069)3.13992139
144lipid oxidation (GO:0034440)3.12451889
145ketone body metabolic process (GO:1902224)3.12289944
146regulation of centriole replication (GO:0046599)3.11890478
147mitotic spindle assembly checkpoint (GO:0007094)3.11793882
148attachment of spindle microtubules to kinetochore (GO:0008608)3.11354377
149mitochondrial RNA metabolic process (GO:0000959)3.11022631
150pantothenate metabolic process (GO:0015939)3.10935500
151cullin deneddylation (GO:0010388)3.10882498
152resolution of meiotic recombination intermediates (GO:0000712)3.10832843
153histone mRNA metabolic process (GO:0008334)3.10431287
154nucleobase biosynthetic process (GO:0046112)3.09938771
155folic acid-containing compound biosynthetic process (GO:0009396)3.08178624
156regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.07831266
157oxaloacetate metabolic process (GO:0006107)3.07423534
158mitotic G2/M transition checkpoint (GO:0044818)3.07361444
159mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.07341348
160spindle assembly checkpoint (GO:0071173)3.07297974
161regulation of bile acid biosynthetic process (GO:0070857)3.06445216
162carnitine shuttle (GO:0006853)3.06127279
163establishment of integrated proviral latency (GO:0075713)3.05825072
164pyridine-containing compound biosynthetic process (GO:0072525)3.05790136
165regulation of mitochondrial translation (GO:0070129)3.05702386
166RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.05110325
167regulation of helicase activity (GO:0051095)3.04657818
168DNA catabolic process, exonucleolytic (GO:0000738)3.04413342
169mitotic sister chromatid cohesion (GO:0007064)3.04338031
170kinetochore assembly (GO:0051382)3.03676652
171response to nitrosative stress (GO:0051409)3.03525874
172somatic diversification of immunoglobulins involved in immune response (GO:0002208)3.03369543
173isotype switching (GO:0045190)3.03369543
174somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)3.03369543
175reverse cholesterol transport (GO:0043691)3.03049263
176regulation of meiosis I (GO:0060631)3.02883470
177short-chain fatty acid metabolic process (GO:0046459)3.01700762
178anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.01051526
179sulfur amino acid metabolic process (GO:0000096)3.00680818
180transcription from mitochondrial promoter (GO:0006390)3.00382801
181dicarboxylic acid metabolic process (GO:0043648)2.99367944
182L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.98365680
183regulation of chromosome segregation (GO:0051983)2.98249711
184fatty acid catabolic process (GO:0009062)2.97959962
185sister chromatid segregation (GO:0000819)2.97566724
186rRNA methylation (GO:0031167)2.97200925
187nuclear envelope disassembly (GO:0051081)2.96646293
188membrane disassembly (GO:0030397)2.96646293
189negative regulation of cholesterol transport (GO:0032375)2.96608150
190negative regulation of sterol transport (GO:0032372)2.96608150
191mitotic sister chromatid segregation (GO:0000070)2.95984617
192tetrahydrofolate metabolic process (GO:0046653)2.95607718
193mitotic metaphase plate congression (GO:0007080)2.95067820
194positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.94003955
195protein localization to chromosome, centromeric region (GO:0071459)2.93937610
196regulation of nuclear cell cycle DNA replication (GO:0033262)2.92296638
197positive regulation of chromosome segregation (GO:0051984)2.91121625

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse7.13006286
2E2F7_22180533_ChIP-Seq_HELA_Human5.31481765
3EGR1_23403033_ChIP-Seq_LIVER_Mouse5.03440605
4RXR_22158963_ChIP-Seq_LIVER_Mouse4.83406046
5PPARA_22158963_ChIP-Seq_LIVER_Mouse4.20454606
6CEBPA_23403033_ChIP-Seq_LIVER_Mouse3.76350358
7CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.50626765
8LXR_22158963_ChIP-Seq_LIVER_Mouse3.45769927
9PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.01500702
10FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.83394362
11MYC_18555785_ChIP-Seq_MESCs_Mouse2.79602423
12KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.45139953
13E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.26191998
14E2F4_17652178_ChIP-ChIP_JURKAT_Human2.10922507
15TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.10045333
16NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.09958678
17FOXM1_23109430_ChIP-Seq_U2OS_Human2.05362584
18FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.04467550
19JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.98258282
20AR_21909140_ChIP-Seq_LNCAP_Human1.97109902
21EST1_17652178_ChIP-ChIP_JURKAT_Human1.95272961
22KAP1_22055183_ChIP-Seq_ESCs_Mouse1.91147557
23PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.90800846
24SALL1_21062744_ChIP-ChIP_HESCs_Human1.90200903
25KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.84348377
26RBPJ_22232070_ChIP-Seq_NCS_Mouse1.82575652
27BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.79303174
28MYC_19030024_ChIP-ChIP_MESCs_Mouse1.76030137
29* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.74898173
30HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.74267415
31MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.71094634
32CREB1_15753290_ChIP-ChIP_HEK293T_Human1.70256148
33* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.67263739
34GATA1_22025678_ChIP-Seq_K562_Human1.66263247
35FUS_26573619_Chip-Seq_HEK293_Human1.65789364
36VDR_22108803_ChIP-Seq_LS180_Human1.64692064
37EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.64286933
38GABP_17652178_ChIP-ChIP_JURKAT_Human1.62710585
39EWS_26573619_Chip-Seq_HEK293_Human1.59698969
40* ETS1_20019798_ChIP-Seq_JURKAT_Human1.58822024
41TTF2_22483619_ChIP-Seq_HELA_Human1.58075092
42ELF1_17652178_ChIP-ChIP_JURKAT_Human1.57525527
43NELFA_20434984_ChIP-Seq_ESCs_Mouse1.57135733
44IGF1R_20145208_ChIP-Seq_DFB_Human1.56675034
45SRF_21415370_ChIP-Seq_HL-1_Mouse1.50970968
46FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.50109480
47MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.50092604
48ZNF274_21170338_ChIP-Seq_K562_Hela1.42702635
49MYCN_18555785_ChIP-Seq_MESCs_Mouse1.42517350
50HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.41529691
51YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.40993236
52E2F1_18555785_ChIP-Seq_MESCs_Mouse1.40292345
53FOXP3_21729870_ChIP-Seq_TREG_Human1.33318139
54STAT3_1855785_ChIP-Seq_MESCs_Mouse1.31855101
55FLI1_27457419_Chip-Seq_LIVER_Mouse1.29032586
56FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.28329645
57NANOG_18555785_ChIP-Seq_MESCs_Mouse1.28141435
58* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.25764396
59VDR_23849224_ChIP-Seq_CD4+_Human1.25096796
60E2F1_21310950_ChIP-Seq_MCF-7_Human1.24337403
61PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.22539143
62CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.21162441
63MYC_19079543_ChIP-ChIP_MESCs_Mouse1.19068293
64HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.17950035
65DCP1A_22483619_ChIP-Seq_HELA_Human1.17067533
66HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.14801224
67GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12938828
68ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.12315804
69NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.12231306
70TAF15_26573619_Chip-Seq_HEK293_Human1.12080237
71ZFX_18555785_ChIP-Seq_MESCs_Mouse1.11763774
72NANOG_16153702_ChIP-ChIP_HESCs_Human1.11387036
73PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.10330733
74TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.09689155
75POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.07673755
76ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.07658271
77IRF1_19129219_ChIP-ChIP_H3396_Human1.04675424
78HTT_18923047_ChIP-ChIP_STHdh_Human1.04159424
79HOXB4_20404135_ChIP-ChIP_EML_Mouse1.03921290
80E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.03450609
81PCGF2_27294783_Chip-Seq_ESCs_Mouse1.03157027
82MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.02487456
83THAP11_20581084_ChIP-Seq_MESCs_Mouse1.01977439
84POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.01173773
85STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.01062716
86* HNF4A_19822575_ChIP-Seq_HepG2_Human1.00095122
87NFE2_27457419_Chip-Seq_LIVER_Mouse0.98671827
88IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.98555743
89RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.98447302
90GABP_19822575_ChIP-Seq_HepG2_Human0.97062279
91SOX2_16153702_ChIP-ChIP_HESCs_Human0.96377257
92SUZ12_27294783_Chip-Seq_NPCs_Mouse0.95666300
93NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.94611885
94CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.94259563
95TP63_19390658_ChIP-ChIP_HaCaT_Human0.93508085
96PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.93477492
97YY1_21170310_ChIP-Seq_MESCs_Mouse0.93286978
98KDM5A_27292631_Chip-Seq_BREAST_Human0.93086735
99RXRA_24833708_ChIP-Seq_LIVER_Mouse0.92274488
100SALL4_22934838_ChIP-ChIP_CD34+_Human0.91391114
101POU5F1_16153702_ChIP-ChIP_HESCs_Human0.89952537
102BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.89567061
103STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.89176012
104NOTCH1_21737748_ChIP-Seq_TLL_Human0.88653095
105SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.88535867
106CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.88318298
107XRN2_22483619_ChIP-Seq_HELA_Human0.87585497
108MYC_18940864_ChIP-ChIP_HL60_Human0.87260802
109CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.87136085
110ZFP57_27257070_Chip-Seq_ESCs_Mouse0.86168150
111ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.83961138
112P300_19829295_ChIP-Seq_ESCs_Human0.83481317
113CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.82936291
114TFEB_21752829_ChIP-Seq_HELA_Human0.81543488
115TP53_22573176_ChIP-Seq_HFKS_Human0.80692937
116SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.79783314
117HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.79432685
118POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.79358081
119SOX17_20123909_ChIP-Seq_XEN_Mouse0.78311624
120ELK1_19687146_ChIP-ChIP_HELA_Human0.78102634
121GATA4_21415370_ChIP-Seq_HL-1_Mouse0.76096580
122EZH2_27294783_Chip-Seq_NPCs_Mouse0.75036960
123KLF4_18555785_ChIP-Seq_MESCs_Mouse0.74339384
124ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.73942813
125* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.73181634
126AUTS2_25519132_ChIP-Seq_293T-REX_Human0.73144617
127CIITA_25753668_ChIP-Seq_RAJI_Human0.72934493
128PCGF2_27294783_Chip-Seq_NPCs_Mouse0.72834876
129ERG_20887958_ChIP-Seq_HPC-7_Mouse0.71395541
130NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.69058481
131SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.67529117

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system6.92417008
2MP0005360_urolithiasis6.03502378
3MP0005085_abnormal_gallbladder_physiolo5.46263209
4MP0005365_abnormal_bile_salt5.33022608
5MP0003806_abnormal_nucleotide_metabolis4.61829715
6MP0008875_abnormal_xenobiotic_pharmacok4.16396746
7MP0004147_increased_porphyrin_level3.17201484
8MP0003252_abnormal_bile_duct2.95482433
9MP0003646_muscle_fatigue2.93305827
10MP0010329_abnormal_lipoprotein_level2.71779628
11MP0003195_calcinosis2.53811255
12MP0005332_abnormal_amino_acid2.49971950
13MP0003693_abnormal_embryo_hatching2.35236740
14MP0005451_abnormal_body_composition2.24770816
15MP0006292_abnormal_olfactory_placode2.24285820
16MP0009697_abnormal_copulation2.22495661
17MP0000372_irregular_coat_pigmentation2.06154481
18MP0001764_abnormal_homeostasis1.91462394
19MP0005083_abnormal_biliary_tract1.91138145
20MP0000609_abnormal_liver_physiology1.89902152
21MP0010094_abnormal_chromosome_stability1.88091111
22MP0003941_abnormal_skin_development1.85547969
23MP0005319_abnormal_enzyme/_coenzyme1.77107287
24MP0008057_abnormal_DNA_replication1.76190168
25MP0003718_maternal_effect1.74634381
26MP0006036_abnormal_mitochondrial_physio1.69956305
27MP0003111_abnormal_nucleus_morphology1.66862427
28MP0009840_abnormal_foam_cell1.65324895
29MP0001529_abnormal_vocalization1.63508478
30MP0004957_abnormal_blastocyst_morpholog1.59641259
31MP0002118_abnormal_lipid_homeostasis1.58973150
32MP0005647_abnormal_sex_gland1.58047075
33MP0001666_abnormal_nutrient_absorption1.56830893
34MP0003186_abnormal_redox_activity1.56711609
35MP0004019_abnormal_vitamin_homeostasis1.52200204
36MP0008058_abnormal_DNA_repair1.44389542
37MP0003077_abnormal_cell_cycle1.43745598
38MP0006072_abnormal_retinal_apoptosis1.42318609
39MP0005266_abnormal_metabolism1.37781187
40MP0001293_anophthalmia1.37610808
41MP0003656_abnormal_erythrocyte_physiolo1.33337354
42MP0003191_abnormal_cellular_cholesterol1.31299840
43MP0000358_abnormal_cell_content/1.29955454
44MP0003121_genomic_imprinting1.25357551
45MP0005584_abnormal_enzyme/coenzyme_acti1.25322225
46MP0008877_abnormal_DNA_methylation1.23467559
47MP0003868_abnormal_feces_composition1.22862350
48MP0008775_abnormal_heart_ventricle1.22181164
49MP0006035_abnormal_mitochondrial_morpho1.19747265
50MP0005075_abnormal_melanosome_morpholog1.18799150
51MP0005670_abnormal_white_adipose1.16625106
52MP0003786_premature_aging1.12892008
53MP0002938_white_spotting1.12842431
54MP0002084_abnormal_developmental_patter1.11089365
55MP0008789_abnormal_olfactory_epithelium1.09086032
56MP0002160_abnormal_reproductive_system1.07541174
57MP0000598_abnormal_liver_morphology1.07356157
58MP0004145_abnormal_muscle_electrophysio1.06367880
59MP0002080_prenatal_lethality1.06249143
60MP0002254_reproductive_system_inflammat1.03908027
61MP0003787_abnormal_imprinting1.03656559
62MP0002138_abnormal_hepatobiliary_system1.01103796
63MP0000313_abnormal_cell_death1.00780364
64MP0003221_abnormal_cardiomyocyte_apopto1.00714700
65MP0002396_abnormal_hematopoietic_system1.00616816
66MP0009763_increased_sensitivity_to1.00276461
67MP0009643_abnormal_urine_homeostasis0.98242249
68MP0004130_abnormal_muscle_cell0.98079101
69MP0002102_abnormal_ear_morphology0.96989742
70MP0002837_dystrophic_cardiac_calcinosis0.96874558
71MP0002090_abnormal_vision0.95570915
72MP0001984_abnormal_olfaction0.92073973
73MP0001119_abnormal_female_reproductive0.90706405
74MP0005253_abnormal_eye_physiology0.89451408
75MP0001661_extended_life_span0.88964542
76MP0005376_homeostasis/metabolism_phenot0.88932745
77MP0003123_paternal_imprinting0.88604976
78MP0001730_embryonic_growth_arrest0.84673260
79MP0001188_hyperpigmentation0.84306834
80MP0003699_abnormal_female_reproductive0.84174420
81MP0002234_abnormal_pharynx_morphology0.83637281
82MP0003698_abnormal_male_reproductive0.81951988
83MP0003937_abnormal_limbs/digits/tail_de0.81688119
84MP0004084_abnormal_cardiac_muscle0.80805234
85MP0002269_muscular_atrophy0.80748848
86MP0002085_abnormal_embryonic_tissue0.80470728
87MP0009672_abnormal_birth_weight0.80200650
88MP0001672_abnormal_embryogenesis/_devel0.78011524
89MP0005380_embryogenesis_phenotype0.78011524
90MP0002095_abnormal_skin_pigmentation0.77790792
91MP0002876_abnormal_thyroid_physiology0.77737477
92MP0005499_abnormal_olfactory_system0.77475138
93MP0005394_taste/olfaction_phenotype0.77475138
94MP0004215_abnormal_myocardial_fiber0.76138574
95MP0002210_abnormal_sex_determination0.75610482
96MP0005395_other_phenotype0.75556016
97MP0010307_abnormal_tumor_latency0.75144167
98MP0001929_abnormal_gametogenesis0.75034292
99MP0003137_abnormal_impulse_conducting0.74503432
100MP0005330_cardiomyopathy0.73716840
101MP0005551_abnormal_eye_electrophysiolog0.72855213
102MP0008007_abnormal_cellular_replicative0.72758286
103MP0002009_preneoplasia0.72399255
104MP0002019_abnormal_tumor_incidence0.72129502
105MP0004036_abnormal_muscle_relaxation0.72071449
106MP0002971_abnormal_brown_adipose0.71516964
107MP0003119_abnormal_digestive_system0.71437708
108MP0004197_abnormal_fetal_growth/weight/0.70060448
109MP0003984_embryonic_growth_retardation0.69406120
110MP0005645_abnormal_hypothalamus_physiol0.69286449
111MP0005389_reproductive_system_phenotype0.68858868
112MP0002078_abnormal_glucose_homeostasis0.68499938
113MP0009765_abnormal_xenobiotic_induced0.68435053
114MP0008469_abnormal_protein_level0.67192851
115MP0008961_abnormal_basal_metabolism0.67106305
116MP0009642_abnormal_blood_homeostasis0.66686802
117MP0005666_abnormal_adipose_tissue0.66195465
118MP0003890_abnormal_embryonic-extraembry0.65767262
119MP0009703_decreased_birth_body0.65731736
120MP0003567_abnormal_fetal_cardiomyocyte0.65578582
121MP0001485_abnormal_pinna_reflex0.65404265
122MP0002088_abnormal_embryonic_growth/wei0.64336214
123MP0001727_abnormal_embryo_implantation0.64259404
124MP0005636_abnormal_mineral_homeostasis0.63972904
125MP0000653_abnormal_sex_gland0.63969303
126MP0002653_abnormal_ependyma_morphology0.63539914
127MP0002163_abnormal_gland_morphology0.62864438
128MP0005379_endocrine/exocrine_gland_phen0.62159482
129MP0004264_abnormal_extraembryonic_tissu0.60601016
130MP0008995_early_reproductive_senescence0.60586302
131MP0005408_hypopigmentation0.60574095
132MP0005535_abnormal_body_temperature0.58160145
133MP0008932_abnormal_embryonic_tissue0.58035327
134MP0001145_abnormal_male_reproductive0.57490915
135MP0000350_abnormal_cell_proliferation0.55577001
136MP0005397_hematopoietic_system_phenotyp0.55000043
137MP0001545_abnormal_hematopoietic_system0.55000043
138MP0009764_decreased_sensitivity_to0.54563174
139MP0002970_abnormal_white_adipose0.54209363
140MP0005220_abnormal_exocrine_pancreas0.53750133
141MP0005334_abnormal_fat_pad0.52223954
142MP0001697_abnormal_embryo_size0.51978427
143MP0002086_abnormal_extraembryonic_tissu0.50699854
144MP0010352_gastrointestinal_tract_polyps0.49967685
145MP0002332_abnormal_exercise_endurance0.49661773
146MP0003011_delayed_dark_adaptation0.48994111

Predicted human phenotypes

RankGene SetZ-score
1Intrahepatic cholestasis (HP:0001406)5.42934179
2Hypobetalipoproteinemia (HP:0003563)5.29699342
3Abnormality of aromatic amino acid family metabolism (HP:0004338)5.21023735
4Abnormality of monocarboxylic acid metabolism (HP:0010996)5.05567330
5Hyperglycinemia (HP:0002154)4.82561304
6Hyperglycinuria (HP:0003108)4.76923199
7Deep venous thrombosis (HP:0002625)4.53734077
8Prolonged partial thromboplastin time (HP:0003645)4.39603510
9Abnormality of glycine metabolism (HP:0010895)4.31831011
10Abnormality of serine family amino acid metabolism (HP:0010894)4.31831011
11Hyperammonemia (HP:0001987)4.28788208
12Abnormality of methionine metabolism (HP:0010901)4.26026209
13Abnormality of aspartate family amino acid metabolism (HP:0010899)3.99908748
14Xanthomatosis (HP:0000991)3.99249655
15Hypolipoproteinemia (HP:0010981)3.96907466
16Abnormality of sulfur amino acid metabolism (HP:0004339)3.94041261
17Abnormality of serum amino acid levels (HP:0003112)3.92579359
18Hyperlipoproteinemia (HP:0010980)3.89093873
19Abnormality of pyrimidine metabolism (HP:0004353)3.84140161
20Ketosis (HP:0001946)3.82918353
21Abnormality of fatty-acid metabolism (HP:0004359)3.79044371
22Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.62152106
23Complement deficiency (HP:0004431)3.58783413
24Acute necrotizing encephalopathy (HP:0006965)3.49234087
25Abnormality of glutamine family amino acid metabolism (HP:0010902)3.48912003
26Hypoglycemic coma (HP:0001325)3.44999318
27Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.43401643
28Joint hemorrhage (HP:0005261)3.40724912
29Hypoalphalipoproteinemia (HP:0003233)3.37398204
30Epidermoid cyst (HP:0200040)3.29845953
31Abnormality of dicarboxylic acid metabolism (HP:0010995)3.26745166
32Dicarboxylic aciduria (HP:0003215)3.26745166
33Renal cortical cysts (HP:0000803)3.22391510
34Abnormal mitochondria in muscle tissue (HP:0008316)3.19885312
35Progressive macrocephaly (HP:0004481)3.11850289
36Fat malabsorption (HP:0002630)3.10599321
37Lethargy (HP:0001254)3.06381544
38Abnormality of nucleobase metabolism (HP:0010932)3.04961557
39Cerebral edema (HP:0002181)3.04543347
40Increased CSF lactate (HP:0002490)3.00995936
41Abnormality of the intrinsic pathway (HP:0010989)3.00289399
42Abnormality of the labia minora (HP:0012880)2.99126251
43Methylmalonic acidemia (HP:0002912)2.92001465
44Proximal tubulopathy (HP:0000114)2.88578755
45Abnormality of the common coagulation pathway (HP:0010990)2.85141212
46Colon cancer (HP:0003003)2.84243678
47Delayed CNS myelination (HP:0002188)2.84004867
48Metabolic acidosis (HP:0001942)2.82492635
49Ketoacidosis (HP:0001993)2.82443001
50Increased hepatocellular lipid droplets (HP:0006565)2.77673491
51Conjugated hyperbilirubinemia (HP:0002908)2.76774763
52Generalized aminoaciduria (HP:0002909)2.73252466
53Mitochondrial inheritance (HP:0001427)2.73214790
54Pancreatic islet-cell hyperplasia (HP:0004510)2.68790170
55Hepatic necrosis (HP:0002605)2.68540648
56Abnormality of purine metabolism (HP:0004352)2.65372255
57Hyperbilirubinemia (HP:0002904)2.61418993
58Abnormal lung lobation (HP:0002101)2.60370166
59Lipid accumulation in hepatocytes (HP:0006561)2.59883109
60Multiple enchondromatosis (HP:0005701)2.57521452
61Microvesicular hepatic steatosis (HP:0001414)2.56245465
62Hypercholesterolemia (HP:0003124)2.53770331
63Aplasia/Hypoplasia of the uvula (HP:0010293)2.52037125
64Gout (HP:0001997)2.51903898
65Nausea (HP:0002018)2.49906886
66Neoplasm of the adrenal gland (HP:0100631)2.45519326
67Meckel diverticulum (HP:0002245)2.43874357
68Abnormality of homocysteine metabolism (HP:0010919)2.42051066
69Homocystinuria (HP:0002156)2.42051066
70Impulsivity (HP:0100710)2.41638465
71Hypoglycemic seizures (HP:0002173)2.40569273
72Nephroblastoma (Wilms tumor) (HP:0002667)2.40211976
73Volvulus (HP:0002580)2.40200509
74Abnormality of complement system (HP:0005339)2.39925378
75Steatorrhea (HP:0002570)2.39423822
76Oral leukoplakia (HP:0002745)2.37261832
77Abnormality of the ileum (HP:0001549)2.36827008
78Chromsome breakage (HP:0040012)2.35572410
79Abnormality of the preputium (HP:0100587)2.34771869
80Hypochromic microcytic anemia (HP:0004840)2.34216298
81Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.32434592
82Abnormality of alanine metabolism (HP:0010916)2.32434592
83Hyperalaninemia (HP:0003348)2.32434592
84Small intestinal stenosis (HP:0012848)2.32198266
85Duodenal stenosis (HP:0100867)2.32198266
86Palpitations (HP:0001962)2.31935868
87Chromosomal breakage induced by crosslinking agents (HP:0003221)2.31064146
88Hyperglycemia (HP:0003074)2.28756625
89Spontaneous abortion (HP:0005268)2.28458216
90Rhabdomyolysis (HP:0003201)2.27720082
91Hyperuricemia (HP:0002149)2.26511786
92Increased purine levels (HP:0004368)2.26511786
93Rhabdomyosarcoma (HP:0002859)2.26147271
94Limb hypertonia (HP:0002509)2.25746573
95Embryonal renal neoplasm (HP:0011794)2.25333864
96Hepatocellular carcinoma (HP:0001402)2.23690287
97Abnormality of glycolysis (HP:0004366)2.22705927
98Increased serum pyruvate (HP:0003542)2.22705927
99Hyperinsulinemic hypoglycemia (HP:0000825)2.22213166
100Ependymoma (HP:0002888)2.21577322
101Supernumerary spleens (HP:0009799)2.21321392
102Birth length less than 3rd percentile (HP:0003561)2.21286309
103Abnormality of the vitamin B12 metabolism (HP:0004341)2.18934838
104Abnormality of vitamin B metabolism (HP:0004340)2.18014611
105Neoplasm of the small intestine (HP:0100833)2.17389322
106Abnormality of lateral ventricle (HP:0030047)2.16944476
107Neoplasm of the colon (HP:0100273)2.14719405
108Progressive external ophthalmoplegia (HP:0000590)2.12604742
109Gonadotropin excess (HP:0000837)2.07449545
110Hepatocellular necrosis (HP:0001404)2.06937240
111Type I transferrin isoform profile (HP:0003642)2.05506160
112Abnormality of the duodenum (HP:0002246)2.04601078
113Hypoplasia of the thymus (HP:0000778)2.04047666
114Central scotoma (HP:0000603)2.02258295
1153-Methylglutaconic aciduria (HP:0003535)2.00540474
116Spastic diplegia (HP:0001264)1.95846518
117Abnormal cartilage morphology (HP:0002763)1.95726983
118Sloping forehead (HP:0000340)1.94908075
119Myelodysplasia (HP:0002863)1.93885581
120Exercise intolerance (HP:0003546)1.93761347
121Symptomatic seizures (HP:0011145)1.92383663
122Methylmalonic aciduria (HP:0012120)1.91414939
123Aplasia/Hypoplasia involving the musculature (HP:0001460)1.90930709
124CNS demyelination (HP:0007305)1.90061892
125Acanthocytosis (HP:0001927)1.89349321
126Medulloblastoma (HP:0002885)1.89266527
127Biliary tract neoplasm (HP:0100574)1.88771467
128Acute hepatic failure (HP:0006554)1.88733426
129Abnormality of endocrine pancreas physiology (HP:0012093)1.87929985
130Abnormality of the pancreatic islet cells (HP:0006476)1.87929985
131Ovarian neoplasm (HP:0100615)1.87535898
132Premature ovarian failure (HP:0008209)1.87250820
133Myoglobinuria (HP:0002913)1.86937047
134Glioma (HP:0009733)1.86867719
135Irritability (HP:0000737)1.85832678
136Type 2 muscle fiber atrophy (HP:0003554)1.84463316
137Cerebral hypomyelination (HP:0006808)1.84347424
138Acute encephalopathy (HP:0006846)1.84291627
139Lactic acidosis (HP:0003128)1.83249871
140Agnosia (HP:0010524)1.82703144
141Adenoma sebaceum (HP:0009720)1.82421696
142Angiofibromas (HP:0010615)1.82421696
143Hydroxyprolinuria (HP:0003080)1.81668356
144Abnormality of proline metabolism (HP:0010907)1.81668356
145Vomiting (HP:0002013)1.80448855
146Abnormality of chromosome stability (HP:0003220)1.80393193
147Abnormality of the renal cortex (HP:0011035)1.79924072
148Elevated hepatic transaminases (HP:0002910)1.79702447
149Acute myeloid leukemia (HP:0004808)1.78693423
150Leukodystrophy (HP:0002415)1.78537172
151Respiratory failure (HP:0002878)1.77912417
152Increased intramyocellular lipid droplets (HP:0012240)1.77841438
153Intestinal atresia (HP:0011100)1.77437114
154Skin nodule (HP:0200036)1.77046663
155Cholelithiasis (HP:0001081)1.76966077
156Neoplasm of the rectum (HP:0100743)1.76872027
157Fair hair (HP:0002286)1.76688198
158Posterior subcapsular cataract (HP:0007787)1.76265046
159Abnormal protein glycosylation (HP:0012346)1.75609658
160Abnormal glycosylation (HP:0012345)1.75609658
161Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.75609658
162Abnormal protein N-linked glycosylation (HP:0012347)1.75609658
163Myocardial infarction (HP:0001658)1.75180980
164Ragged-red muscle fibers (HP:0003200)1.74637929
165Neoplasm of the adrenal cortex (HP:0100641)1.73596411
166Aplastic anemia (HP:0001915)1.73196766
167Abnormality of vitamin metabolism (HP:0100508)1.73038865
168Megaloblastic anemia (HP:0001889)1.70395561
169Increased serum lactate (HP:0002151)1.69924012
170Abnormal spermatogenesis (HP:0008669)1.69204473
171Brushfield spots (HP:0001088)1.68796464
172Poikilocytosis (HP:0004447)1.68099782

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK3.97669657
2ACVR1B3.69190220
3LATS13.05661001
4STK38L3.03385833
5PLK42.83234569
6WEE12.61616964
7ERBB42.59545682
8PBK2.45477658
9NUAK12.43682998
10NEK12.40558171
11ZAK2.37573751
12TAOK32.29700185
13MST42.12700906
14PDK42.07781345
15PDK32.07781345
16CDC72.03980646
17EIF2AK11.98891005
18MAP4K21.93195525
19FGFR41.91774513
20PINK11.88175012
21SRPK11.84309283
22BUB11.81116180
23TTK1.75504378
24SIK31.74825696
25NEK21.74690732
26TRIM281.73694382
27EPHA31.70683302
28MAP3K61.68295816
29LATS21.64475872
30BRSK21.60258390
31FRK1.56216030
32MAPK111.54627957
33WNK31.54507729
34PLK31.50571159
35AKT31.47649877
36NEK91.47495141
37STK161.42756587
38CDK41.36777155
39PNCK1.35624036
40BMPR1B1.34900626
41TAF11.34587159
42SGK21.32258938
43CCNB11.31825501
44NME11.30192940
45RPS6KA41.29998191
46TSSK61.28764308
47TNIK1.26927587
48MKNK21.26887832
49PLK11.26478549
50ERBB31.19921023
51STK31.12804007
52CDK121.12231626
53ATR1.11704004
54MAP2K31.08213807
55MAP3K51.08001509
56CSNK1G11.07296640
57MAP3K41.05082581
58PDK21.04675144
59OBSCN1.03777243
60BRSK11.03681453
61AURKB0.96321530
62STK40.96118916
63BCR0.93252840
64FGFR30.92061667
65VRK20.90786800
66FLT30.87723677
67CDK70.87332882
68PRKAA10.87158551
69SGK30.85777358
70PKN20.85719062
71TEC0.84621602
72CSNK1G30.83497138
73SCYL20.83462322
74VRK10.80753877
75BRAF0.80476199
76TYK20.79124102
77EIF2AK30.78530613
78BMPR20.77564664
79EIF2AK20.77021682
80PRKAA20.76920470
81TAOK10.76069497
82MUSK0.74524010
83MELK0.73559549
84ALK0.73017003
85OXSR10.72646375
86CSNK1G20.71241161
87MAP3K80.71140895
88PLK20.71001495
89CLK10.70560400
90PASK0.70453506
91MKNK10.70371876
92RPS6KB10.70141081
93DYRK30.69252011
94CDK30.68864698
95CHEK10.68853200
96EEF2K0.68385335
97MAP3K130.67972915
98BRD40.66916907
99CDK190.66905406
100SIK10.66448862
101MAP2K40.66003529
102CSNK2A20.64233194
103ABL20.63936322
104CHEK20.62284504
105ATM0.62243737
106CHUK0.61614146
107PIM10.59468863
108CSNK1E0.59355411
109CSNK1A1L0.58517269
110MAP3K30.56834732
111RPS6KB20.56748837
112STK390.56537832
113TAOK20.55983307
114CAMK40.55601607
115FGFR10.54221744
116CSNK2A10.53943585
117JAK30.53328460
118JAK20.52783358
119KSR10.51434752
120INSRR0.50036106
121IRAK30.49379968
122MAP3K140.49179568
123CDK20.47994176
124MAPKAPK30.46340703
125TXK0.45723605
126CDK60.44668248
127CDK80.44242896
128PHKG10.42546663
129PHKG20.42546663
130ADRBK20.41120939
131TGFBR10.41077430
132GRK10.40982054
133NME20.39161287
134JAK10.38920018
135PRKDC0.37527417
136CDK90.36806475
137CDK10.36698585
138AKT20.36651825
139RPS6KA50.36433815
140STK240.33923288
141ERBB20.33306806
142STK380.30749747
143AKT10.30199315
144RAF10.29985363
145PRKACB0.29913965
146MAPK130.25923249
147CSNK1A10.23838286
148AURKA0.23404192
149EPHA40.22897332
150MAPKAPK50.21699585

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001203.40660071
2Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.01758841
3Protein export_Homo sapiens_hsa030602.89639591
4Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.87049002
5Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.68049110
6Fatty acid degradation_Homo sapiens_hsa000712.58122962
7Propanoate metabolism_Homo sapiens_hsa006402.51235870
8Arginine biosynthesis_Homo sapiens_hsa002202.50593256
9Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.44985045
102-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.38019272
11Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.36744234
12Vitamin B6 metabolism_Homo sapiens_hsa007502.25291194
13Tryptophan metabolism_Homo sapiens_hsa003802.21008431
14Pantothenate and CoA biosynthesis_Homo sapiens_hsa007702.13435510
15Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.05012273
16Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.01293215
17Nitrogen metabolism_Homo sapiens_hsa009102.00643836
18Pentose and glucuronate interconversions_Homo sapiens_hsa000401.95881969
19Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.91066038
20Peroxisome_Homo sapiens_hsa041461.91018951
21Drug metabolism - other enzymes_Homo sapiens_hsa009831.89882321
22Parkinsons disease_Homo sapiens_hsa050121.89608129
23Butanoate metabolism_Homo sapiens_hsa006501.87237595
24Oxidative phosphorylation_Homo sapiens_hsa001901.85796497
25Caffeine metabolism_Homo sapiens_hsa002321.84397039
26Fatty acid metabolism_Homo sapiens_hsa012121.84170014
27Complement and coagulation cascades_Homo sapiens_hsa046101.81209046
28Cysteine and methionine metabolism_Homo sapiens_hsa002701.79171507
29Cyanoamino acid metabolism_Homo sapiens_hsa004601.78992148
30Carbon metabolism_Homo sapiens_hsa012001.78479968
31One carbon pool by folate_Homo sapiens_hsa006701.77474409
32Selenocompound metabolism_Homo sapiens_hsa004501.76712903
33beta-Alanine metabolism_Homo sapiens_hsa004101.74451926
34Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.73973972
35Biosynthesis of amino acids_Homo sapiens_hsa012301.70662128
36Pyruvate metabolism_Homo sapiens_hsa006201.68311651
37Ribosome_Homo sapiens_hsa030101.67942254
38Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.64053761
39PPAR signaling pathway_Homo sapiens_hsa033201.55081181
40Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.47827019
41Chemical carcinogenesis_Homo sapiens_hsa052041.43777530
42Steroid hormone biosynthesis_Homo sapiens_hsa001401.41947328
43Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.37529325
44Folate biosynthesis_Homo sapiens_hsa007901.37212547
45Retinol metabolism_Homo sapiens_hsa008301.33002802
46Starch and sucrose metabolism_Homo sapiens_hsa005001.27507007
47Pentose phosphate pathway_Homo sapiens_hsa000301.26801393
48Histidine metabolism_Homo sapiens_hsa003401.26556759
49Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.26459021
50Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.19034389
51Phenylalanine metabolism_Homo sapiens_hsa003601.12608908
52Oocyte meiosis_Homo sapiens_hsa041141.08718785
53Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.05648192
54RNA polymerase_Homo sapiens_hsa030201.01491896
55Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.01414636
56Staphylococcus aureus infection_Homo sapiens_hsa051501.00684000
57Vitamin digestion and absorption_Homo sapiens_hsa049771.00102121
58Tyrosine metabolism_Homo sapiens_hsa003500.99974317
59Lysine degradation_Homo sapiens_hsa003100.99913598
60Fatty acid elongation_Homo sapiens_hsa000620.99029374
61Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.97987916
62Alzheimers disease_Homo sapiens_hsa050100.96262488
63Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.90628627
64Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.88708714
65Pyrimidine metabolism_Homo sapiens_hsa002400.84360712
66ABC transporters_Homo sapiens_hsa020100.82387590
67Arginine and proline metabolism_Homo sapiens_hsa003300.81074309
68RNA transport_Homo sapiens_hsa030130.79533632
69Bile secretion_Homo sapiens_hsa049760.79062323
70Mismatch repair_Homo sapiens_hsa034300.78833882
71Glutathione metabolism_Homo sapiens_hsa004800.77057336
72Homologous recombination_Homo sapiens_hsa034400.75822481
73Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.74220883
74DNA replication_Homo sapiens_hsa030300.73387653
75Sulfur metabolism_Homo sapiens_hsa009200.72816365
76Cardiac muscle contraction_Homo sapiens_hsa042600.71864057
77Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.69406133
78Sulfur relay system_Homo sapiens_hsa041220.68232338
79Nucleotide excision repair_Homo sapiens_hsa034200.67117391
80N-Glycan biosynthesis_Homo sapiens_hsa005100.65590897
81Fanconi anemia pathway_Homo sapiens_hsa034600.65053080
82Maturity onset diabetes of the young_Homo sapiens_hsa049500.64637896
83RNA degradation_Homo sapiens_hsa030180.64605151
84Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.63484493
85Cell cycle_Homo sapiens_hsa041100.63229241
86Basal transcription factors_Homo sapiens_hsa030220.62824362
87Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.61849647
88Metabolic pathways_Homo sapiens_hsa011000.60298838
89Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.59070610
90Base excision repair_Homo sapiens_hsa034100.57332901
91Fatty acid biosynthesis_Homo sapiens_hsa000610.53826656
92Fat digestion and absorption_Homo sapiens_hsa049750.52708680
93Fructose and mannose metabolism_Homo sapiens_hsa000510.51860228
94Systemic lupus erythematosus_Homo sapiens_hsa053220.47252651
95Glycerolipid metabolism_Homo sapiens_hsa005610.44059686
96Ether lipid metabolism_Homo sapiens_hsa005650.42389070
97Galactose metabolism_Homo sapiens_hsa000520.41519410
98Non-homologous end-joining_Homo sapiens_hsa034500.40189099
99Steroid biosynthesis_Homo sapiens_hsa001000.38878183
100Purine metabolism_Homo sapiens_hsa002300.36529441
101Olfactory transduction_Homo sapiens_hsa047400.35635441
102Phototransduction_Homo sapiens_hsa047440.35438947
103Regulation of autophagy_Homo sapiens_hsa041400.35087456
104Spliceosome_Homo sapiens_hsa030400.33570569
105Glucagon signaling pathway_Homo sapiens_hsa049220.31603309
106Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.31462381
107Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.27930623
108mRNA surveillance pathway_Homo sapiens_hsa030150.25107875
109Epstein-Barr virus infection_Homo sapiens_hsa051690.23337527
110Insulin resistance_Homo sapiens_hsa049310.22910510
111Proteasome_Homo sapiens_hsa030500.22098549
112Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.21611678
113Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.20839284
114p53 signaling pathway_Homo sapiens_hsa041150.17789175
115Alcoholism_Homo sapiens_hsa050340.12098492
116Linoleic acid metabolism_Homo sapiens_hsa005910.12042287
117Herpes simplex infection_Homo sapiens_hsa051680.09360146
118Huntingtons disease_Homo sapiens_hsa050160.06291570
119Adipocytokine signaling pathway_Homo sapiens_hsa049200.06245228
120Glycerophospholipid metabolism_Homo sapiens_hsa005640.05593975
121Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.04018756
122Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.03579650

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