FASTKD5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic metaphase plate congression (GO:0007080)4.58818264
2folic acid-containing compound biosynthetic process (GO:0009396)4.36830575
3nucleobase biosynthetic process (GO:0046112)4.26947563
4DNA unwinding involved in DNA replication (GO:0006268)4.22963016
5protein localization to kinetochore (GO:0034501)4.20980791
6IMP biosynthetic process (GO:0006188)4.05645761
7mitotic nuclear envelope disassembly (GO:0007077)4.03246214
8nuclear pore organization (GO:0006999)4.02505216
9DNA strand elongation involved in DNA replication (GO:0006271)3.97588880
10purine nucleobase biosynthetic process (GO:0009113)3.97453252
11formation of translation preinitiation complex (GO:0001731)3.96125869
12metaphase plate congression (GO:0051310)3.94277424
13mitotic chromosome condensation (GO:0007076)3.91502632
14attachment of spindle microtubules to kinetochore (GO:0008608)3.86500879
15CENP-A containing nucleosome assembly (GO:0034080)3.84241043
16chromatin remodeling at centromere (GO:0031055)3.78459729
17nuclear pore complex assembly (GO:0051292)3.77681114
18DNA strand elongation (GO:0022616)3.75844196
19kinetochore organization (GO:0051383)3.75618106
20nuclear envelope disassembly (GO:0051081)3.74299652
21membrane disassembly (GO:0030397)3.74299652
22ribosome biogenesis (GO:0042254)3.73586726
23ribosomal small subunit assembly (GO:0000028)3.72353644
24protein localization to chromosome, centromeric region (GO:0071459)3.69660994
25mitotic sister chromatid segregation (GO:0000070)3.69285061
26IMP metabolic process (GO:0046040)3.67990373
27ribosome assembly (GO:0042255)3.66294114
28DNA replication initiation (GO:0006270)3.65532846
29DNA replication checkpoint (GO:0000076)3.59830673
30telomere maintenance via semi-conservative replication (GO:0032201)3.53552074
31establishment of chromosome localization (GO:0051303)3.52817448
32cullin deneddylation (GO:0010388)3.49995763
33DNA replication-independent nucleosome assembly (GO:0006336)3.48599584
34DNA replication-independent nucleosome organization (GO:0034724)3.48599584
35protein deneddylation (GO:0000338)3.47468675
36folic acid metabolic process (GO:0046655)3.45466329
37sister chromatid segregation (GO:0000819)3.40422384
38maturation of SSU-rRNA (GO:0030490)3.39446503
39DNA replication-dependent nucleosome organization (GO:0034723)3.38497925
40DNA replication-dependent nucleosome assembly (GO:0006335)3.38497925
41regulation of spindle organization (GO:0090224)3.34782618
42kinetochore assembly (GO:0051382)3.34351593
43regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.32963748
44regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.32707409
45negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.22782454
46ribonucleoprotein complex biogenesis (GO:0022613)3.22478756
47telomere maintenance via recombination (GO:0000722)3.22336093
48mitotic sister chromatid cohesion (GO:0007064)3.21989434
49double-strand break repair via nonhomologous end joining (GO:0006303)3.21165428
50non-recombinational repair (GO:0000726)3.21165428
51histone exchange (GO:0043486)3.19148132
52tetrahydrofolate metabolic process (GO:0046653)3.18843819
53pseudouridine synthesis (GO:0001522)3.18357713
54dosage compensation (GO:0007549)3.17198333
55positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.15868011
56regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.15436430
57anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.13918335
58mitotic recombination (GO:0006312)3.13346128
59regulation of helicase activity (GO:0051095)3.11925743
60meiotic chromosome segregation (GO:0045132)3.10623254
61tRNA aminoacylation for protein translation (GO:0006418)3.10060200
62DNA deamination (GO:0045006)3.09649299
63establishment of viral latency (GO:0019043)3.04464992
64tRNA aminoacylation (GO:0043039)2.99828913
65amino acid activation (GO:0043038)2.99828913
66glycine metabolic process (GO:0006544)2.97305652
67negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.97282619
68negative regulation of ligase activity (GO:0051352)2.97282619
69rRNA processing (GO:0006364)2.96075138
70DNA ligation (GO:0006266)2.95262908
71DNA duplex unwinding (GO:0032508)2.93060560
72nuclear envelope organization (GO:0006998)2.92992630
73folic acid-containing compound metabolic process (GO:0006760)2.92877211
74regulation of translation in response to stress (GO:0043555)2.91577116
75DNA geometric change (GO:0032392)2.91407203
76establishment of integrated proviral latency (GO:0075713)2.90159584
77ribosomal large subunit biogenesis (GO:0042273)2.89076453
78rRNA metabolic process (GO:0016072)2.88596508
79telomere maintenance via telomere lengthening (GO:0010833)2.88504841
80protein localization to chromosome (GO:0034502)2.86202378
81negative regulation of retinoic acid receptor signaling pathway (GO:0048387)2.85956544
82maturation of 5.8S rRNA (GO:0000460)2.85453992
83chromatin assembly or disassembly (GO:0006333)2.84613316
84spindle checkpoint (GO:0031577)2.84316418
85rRNA modification (GO:0000154)2.84231163
86oxidative phosphorylation (GO:0006119)2.83970490
87transcription from mitochondrial promoter (GO:0006390)2.81645081
88proteasome assembly (GO:0043248)2.80546738
89regulation of chromosome segregation (GO:0051983)2.80230439
90pteridine-containing compound biosynthetic process (GO:0042559)2.79865656
91regulation of translational termination (GO:0006449)2.78287161
92spindle assembly checkpoint (GO:0071173)2.77075608
93pore complex assembly (GO:0046931)2.75278060
94pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)2.75191812
95positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.74818243
96negative regulation of histone methylation (GO:0031061)2.74298181
97serine family amino acid biosynthetic process (GO:0009070)2.74018858
98positive regulation of chromosome segregation (GO:0051984)2.74013627
99negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.73738280
100negative regulation of sister chromatid segregation (GO:0033046)2.73738280
101negative regulation of mitotic sister chromatid separation (GO:2000816)2.73738280
102negative regulation of mitotic sister chromatid segregation (GO:0033048)2.73738280
103spliceosomal snRNP assembly (GO:0000387)2.73488924
104negative regulation of chromosome segregation (GO:0051985)2.73265750
105regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.72715970
106positive regulation of ligase activity (GO:0051351)2.72058322
107mitotic spindle assembly checkpoint (GO:0007094)2.71457284
108somatic hypermutation of immunoglobulin genes (GO:0016446)2.71220760
109somatic diversification of immune receptors via somatic mutation (GO:0002566)2.71220760
110regulation of centrosome cycle (GO:0046605)2.70251292
111regulation of mitotic spindle organization (GO:0060236)2.69793067
112chromosome segregation (GO:0007059)2.68649895
113translational initiation (GO:0006413)2.68629599
114L-serine metabolic process (GO:0006563)2.67721694
115nucleotide-excision repair, DNA gap filling (GO:0006297)2.67482667
116negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.67057096
117viral mRNA export from host cell nucleus (GO:0046784)2.66749796
118mitochondrial RNA metabolic process (GO:0000959)2.66743159
119somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.66428336
120isotype switching (GO:0045190)2.66428336
121somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.66428336
122ATP-dependent chromatin remodeling (GO:0043044)2.65625913
123regulation of mitotic metaphase/anaphase transition (GO:0030071)2.65464249
124mitotic spindle checkpoint (GO:0071174)2.65287455
125rRNA methylation (GO:0031167)2.64790015
126regulation of ubiquitin-protein transferase activity (GO:0051438)2.62435532
127DNA catabolic process, exonucleolytic (GO:0000738)2.60864400
128regulation of ligase activity (GO:0051340)2.60666940
129negative regulation of DNA recombination (GO:0045910)2.60137136
130RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.59825586
131histone mRNA metabolic process (GO:0008334)2.57307528
132de novo protein folding (GO:0006458)2.56387238
133regulation of mitotic spindle checkpoint (GO:1903504)2.55862890
134regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.55862890
135regulation of retinoic acid receptor signaling pathway (GO:0048385)2.54837520
136regulation of mitotic sister chromatid separation (GO:0010965)2.53488297
137regulation of mitotic sister chromatid segregation (GO:0033047)2.53488297
138regulation of sister chromatid segregation (GO:0033045)2.53488297
139tricarboxylic acid cycle (GO:0006099)2.51219082
140signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.47750482
141signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.47750482
142signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.47750482
143regulation of cellular amino acid metabolic process (GO:0006521)2.47683146
144DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.47461021
145signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.47349198
146intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.47349198

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.83150603
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.14542229
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.03113899
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.63784784
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.62543677
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.20897516
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.83139277
8* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.76727237
9* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.73830033
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.73028088
11* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.62999804
12GABP_17652178_ChIP-ChIP_JURKAT_Human2.58911866
13ETS1_20019798_ChIP-Seq_JURKAT_Human2.47146006
14* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.46149105
15NELFA_20434984_ChIP-Seq_ESCs_Mouse2.41498758
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.40145057
17EGR1_19374776_ChIP-ChIP_THP-1_Human2.33855585
18AR_21909140_ChIP-Seq_LNCAP_Human2.30982123
19VDR_23849224_ChIP-Seq_CD4+_Human2.23595471
20XRN2_22483619_ChIP-Seq_HELA_Human2.18982001
21CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.11811988
22HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.08121964
23ELF1_17652178_ChIP-ChIP_JURKAT_Human2.03858519
24E2F1_21310950_ChIP-Seq_MCF-7_Human2.02232191
25E2F1_18555785_ChIP-Seq_MESCs_Mouse1.93511588
26MYCN_18555785_ChIP-Seq_MESCs_Mouse1.92868719
27KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.92647370
28* FOXP3_21729870_ChIP-Seq_TREG_Human1.92574446
29MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.89050053
30PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.88781405
31MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.85789005
32SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.84806609
33DCP1A_22483619_ChIP-Seq_HELA_Human1.81969594
34ELK1_19687146_ChIP-ChIP_HELA_Human1.80111809
35E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.75425917
36GABP_19822575_ChIP-Seq_HepG2_Human1.74373047
37POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.69057814
38CIITA_25753668_ChIP-Seq_RAJI_Human1.67448222
39FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.64677221
40TTF2_22483619_ChIP-Seq_HELA_Human1.63967032
41HOXB4_20404135_ChIP-ChIP_EML_Mouse1.61150560
42* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.60067367
43MYC_22102868_ChIP-Seq_BL_Human1.60026238
44PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.59532662
45HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.58062740
46TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.56744778
47NANOG_18555785_ChIP-Seq_MESCs_Mouse1.56454018
48YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.54349113
49NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.53006800
50THAP11_20581084_ChIP-Seq_MESCs_Mouse1.48544162
51KDM5A_27292631_Chip-Seq_BREAST_Human1.47801057
52TP63_19390658_ChIP-ChIP_HaCaT_Human1.45024240
53ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.42745629
54RBPJ_22232070_ChIP-Seq_NCS_Mouse1.39059202
55SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.37663173
56CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.37487660
57CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.31154419
58PADI4_21655091_ChIP-ChIP_MCF-7_Human1.30845803
59SRF_21415370_ChIP-Seq_HL-1_Mouse1.30241040
60ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.29461730
61ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.28256707
62STAT3_1855785_ChIP-Seq_MESCs_Mouse1.28002995
63POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.27951491
64CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.27275929
65MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.25445419
66FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.24904732
67ERG_20887958_ChIP-Seq_HPC-7_Mouse1.23683516
68KLF4_18555785_ChIP-Seq_MESCs_Mouse1.16279618
69NOTCH1_21737748_ChIP-Seq_TLL_Human1.15657182
70MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.15462624
71TFEB_21752829_ChIP-Seq_HELA_Human1.12447200
72SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.12106815
73E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.11848100
74CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.09580597
75ZNF263_19887448_ChIP-Seq_K562_Human1.08902850
76SALL1_21062744_ChIP-ChIP_HESCs_Human1.07275439
77YY1_21170310_ChIP-Seq_MESCs_Mouse1.06697140
78HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.06268403
79PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.05942726
80IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.04929533
81BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.04799911
82DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.03180985
83POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.02605906
84* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.01050732
85EGR1_23403033_ChIP-Seq_LIVER_Mouse0.99643767
86SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.99030804
87GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.98941777
88BP1_19119308_ChIP-ChIP_Hs578T_Human0.98139255
89SPI1_23547873_ChIP-Seq_NB4_Human0.98107143
90MYC_18940864_ChIP-ChIP_HL60_Human0.97834719
91HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.92653819
92STAT4_19710469_ChIP-ChIP_TH1__Mouse0.92424833
93DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.91353408
94CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.91224060
95TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.88496290
96CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.88366943
97ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.88050914
98FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.87421631
99CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.86889324
100MYB_26560356_Chip-Seq_TH2_Human0.86008145
101SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.85951754
102SOX2_18555785_ChIP-Seq_MESCs_Mouse0.85718547
103HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.84753598
104VDR_21846776_ChIP-Seq_THP-1_Human0.84660638
105* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84060235
106IRF8_21731497_ChIP-ChIP_J774_Mouse0.82784189
107NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.82106396
108IRF8_22096565_ChIP-ChIP_GC-B_Human0.80874163
109MYB_21317192_ChIP-Seq_ERMYB_Mouse0.80370596
110MYB_26560356_Chip-Seq_TH1_Human0.79936096
111TCF3_18692474_ChIP-Seq_MEFs_Mouse0.78225024
112GATA1_22025678_ChIP-Seq_K562_Human0.77894484
113CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.77803398
114KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.77443151
115IRF1_19129219_ChIP-ChIP_H3396_Human0.77243782
116NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.76654478

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.81651525
2MP0010094_abnormal_chromosome_stability4.06760892
3MP0003111_abnormal_nucleus_morphology3.91023823
4MP0004957_abnormal_blastocyst_morpholog3.73673598
5MP0003077_abnormal_cell_cycle3.61603452
6MP0003806_abnormal_nucleotide_metabolis3.41225243
7MP0008057_abnormal_DNA_replication3.02905244
8MP0008058_abnormal_DNA_repair2.84870293
9MP0002396_abnormal_hematopoietic_system2.59922770
10MP0008007_abnormal_cellular_replicative2.52122963
11MP0002139_abnormal_hepatobiliary_system2.35797092
12MP0001730_embryonic_growth_arrest2.23293499
13MP0010307_abnormal_tumor_latency2.20681748
14MP0005464_abnormal_platelet_physiology2.12300245
15MP0000350_abnormal_cell_proliferation2.06114317
16MP0003186_abnormal_redox_activity1.99688580
17MP0008932_abnormal_embryonic_tissue1.93937075
18MP0003718_maternal_effect1.89283983
19MP0005360_urolithiasis1.89109523
20MP0005083_abnormal_biliary_tract1.87822364
21MP0005451_abnormal_body_composition1.85596474
22MP0003123_paternal_imprinting1.72645297
23MP0003941_abnormal_skin_development1.70557864
24MP0003786_premature_aging1.61930460
25MP0008877_abnormal_DNA_methylation1.58994479
26MP0005085_abnormal_gallbladder_physiolo1.57361691
27MP0005380_embryogenesis_phenotype1.56510212
28MP0001672_abnormal_embryogenesis/_devel1.56510212
29MP0000490_abnormal_crypts_of1.54759762
30MP0001697_abnormal_embryo_size1.54313321
31MP0004808_abnormal_hematopoietic_stem1.52648734
32MP0010352_gastrointestinal_tract_polyps1.49688923
33MP0009333_abnormal_splenocyte_physiolog1.49410550
34MP0003984_embryonic_growth_retardation1.45977534
35MP0003567_abnormal_fetal_cardiomyocyte1.43881994
36MP0002019_abnormal_tumor_incidence1.43719146
37MP0002088_abnormal_embryonic_growth/wei1.43088469
38MP0002080_prenatal_lethality1.43033692
39MP0003221_abnormal_cardiomyocyte_apopto1.42309293
40MP0005084_abnormal_gallbladder_morpholo1.36137694
41MP0000313_abnormal_cell_death1.35941549
42MP0003656_abnormal_erythrocyte_physiolo1.35678692
43MP0006054_spinal_hemorrhage1.33651785
44MP0003172_abnormal_lysosome_physiology1.33362534
45MP0003011_delayed_dark_adaptation1.29454403
46MP0002086_abnormal_extraembryonic_tissu1.29395914
47MP0003763_abnormal_thymus_physiology1.28998639
48MP0000465_gastrointestinal_hemorrhage1.28931241
49MP0004233_abnormal_muscle_weight1.28034276
50MP0002398_abnormal_bone_marrow1.25869437
51MP0001764_abnormal_homeostasis1.24399902
52MP0005397_hematopoietic_system_phenotyp1.23689337
53MP0001545_abnormal_hematopoietic_system1.23689337
54MP0000689_abnormal_spleen_morphology1.22384509
55MP0005365_abnormal_bile_salt1.21546320
56MP0004197_abnormal_fetal_growth/weight/1.20942347
57MP0002085_abnormal_embryonic_tissue1.15558487
58MP0001853_heart_inflammation1.15101627
59MP0002722_abnormal_immune_system1.14494263
60MP0000372_irregular_coat_pigmentation1.13849695
61MP0001727_abnormal_embryo_implantation1.13051364
62MP0002084_abnormal_developmental_patter1.11744984
63MP0003646_muscle_fatigue1.07237199
64MP0009697_abnormal_copulation1.05142806
65MP0001293_anophthalmia1.02589665
66MP0000598_abnormal_liver_morphology1.02308506
67MP0005075_abnormal_melanosome_morpholog1.00885729
68MP0002429_abnormal_blood_cell0.98940005
69MP0009840_abnormal_foam_cell0.98853343
70MP0000703_abnormal_thymus_morphology0.97664228
71MP0005000_abnormal_immune_tolerance0.96431805
72MP0005058_abnormal_lysosome_morphology0.96152857
73MP0001835_abnormal_antigen_presentation0.95963545
74MP0008260_abnormal_autophagy0.93919244
75MP0006036_abnormal_mitochondrial_physio0.92967061
76MP0001800_abnormal_humoral_immune0.92500120
77MP0009672_abnormal_birth_weight0.92457358
78MP0002132_abnormal_respiratory_system0.91498848
79MP0009053_abnormal_anal_canal0.90160876
80MP0001119_abnormal_female_reproductive0.89356615
81MP0003890_abnormal_embryonic-extraembry0.88536808
82MP0000716_abnormal_immune_system0.88396285
83MP0003566_abnormal_cell_adhesion0.88294047
84MP0002419_abnormal_innate_immunity0.88209953
85MP0001915_intracranial_hemorrhage0.87991959
86MP0003436_decreased_susceptibility_to0.87921896
87MP0008875_abnormal_xenobiotic_pharmacok0.87799176
88MP0000609_abnormal_liver_physiology0.87154149
89MP0002148_abnormal_hypersensitivity_rea0.87110783
90MP0000358_abnormal_cell_content/0.85336899
91MP0005330_cardiomyopathy0.84913180
92MP0002006_tumorigenesis0.83927963
93MP0000015_abnormal_ear_pigmentation0.83712955
94MP0002210_abnormal_sex_determination0.83438572
95MP0005408_hypopigmentation0.83375402
96MP0000858_altered_metastatic_potential0.82759333
97MP0005076_abnormal_cell_differentiation0.82676407
98MP0005266_abnormal_metabolism0.81256145
99MP0003303_peritoneal_inflammation0.80483338
100MP0005621_abnormal_cell_physiology0.80108775
101MP0005671_abnormal_response_to0.80048170
102MP0003705_abnormal_hypodermis_morpholog0.79920792
103MP0005384_cellular_phenotype0.78801440
104MP0009763_increased_sensitivity_to0.77074081
105MP0005319_abnormal_enzyme/_coenzyme0.77045166
106MP0001145_abnormal_male_reproductive0.76678330
107MP0000653_abnormal_sex_gland0.75022952
108MP0009764_decreased_sensitivity_to0.74577924
109MP0002166_altered_tumor_susceptibility0.74432595
110MP0002332_abnormal_exercise_endurance0.74314227
111MP0002102_abnormal_ear_morphology0.73684468
112MP0005023_abnormal_wound_healing0.72900606
113MP0003121_genomic_imprinting0.71456575
114MP0009765_abnormal_xenobiotic_induced0.71148963
115MP0005310_abnormal_salivary_gland0.71049611
116MP0008004_abnormal_stomach_pH0.70619277
117MP0002452_abnormal_antigen_presenting0.69837878
118MP0005395_other_phenotype0.69208385
119MP0001929_abnormal_gametogenesis0.67708548
120MP0004215_abnormal_myocardial_fiber0.67598183
121MP0002723_abnormal_immune_serum0.66891907
122MP0009785_altered_susceptibility_to0.66747782
123MP0002405_respiratory_system_inflammati0.66558883
124MP0004147_increased_porphyrin_level0.65807989
125MP0002420_abnormal_adaptive_immunity0.65480458
126MP0006035_abnormal_mitochondrial_morpho0.65433791
127MP0004264_abnormal_extraembryonic_tissu0.64932445
128MP0010155_abnormal_intestine_physiology0.64662522
129MP0001819_abnormal_immune_cell0.64578509
130MP0003315_abnormal_perineum_morphology0.62758334
131MP0002138_abnormal_hepatobiliary_system0.62697524
132MP0010329_abnormal_lipoprotein_level0.61459514

Predicted human phenotypes

RankGene SetZ-score
1Degeneration of anterior horn cells (HP:0002398)4.04685825
2Abnormality of the anterior horn cell (HP:0006802)4.04685825
3Birth length less than 3rd percentile (HP:0003561)4.01080708
4Microvesicular hepatic steatosis (HP:0001414)3.39214478
5Oral leukoplakia (HP:0002745)3.29387031
6Hypobetalipoproteinemia (HP:0003563)3.23282081
7Ragged-red muscle fibers (HP:0003200)3.22367566
8Breast hypoplasia (HP:0003187)3.07470447
9Multiple enchondromatosis (HP:0005701)3.04312411
10Cholecystitis (HP:0001082)3.03220710
11Abnormal gallbladder physiology (HP:0012438)3.03220710
12Reticulocytopenia (HP:0001896)2.96604902
13Progressive muscle weakness (HP:0003323)2.96516123
14Abnormality of cells of the erythroid lineage (HP:0012130)2.93200477
15Abnormal number of erythroid precursors (HP:0012131)2.93158354
16Impulsivity (HP:0100710)2.91331235
1711 pairs of ribs (HP:0000878)2.90583132
18Abnormality of pyrimidine metabolism (HP:0004353)2.86047112
19Aplastic anemia (HP:0001915)2.85859654
20Progressive external ophthalmoplegia (HP:0000590)2.79369408
21Colon cancer (HP:0003003)2.78598490
22Rhabdomyosarcoma (HP:0002859)2.68894927
23Reduced antithrombin III activity (HP:0001976)2.63175607
24Selective tooth agenesis (HP:0001592)2.60734089
25Carpal bone hypoplasia (HP:0001498)2.59719376
26IgM deficiency (HP:0002850)2.59336191
27Thrombocytosis (HP:0001894)2.52899697
28Agnosia (HP:0010524)2.52772186
29Aplasia/Hypoplasia of the patella (HP:0006498)2.52257030
30Patellar aplasia (HP:0006443)2.51896898
31Myelodysplasia (HP:0002863)2.51279230
32Chromsome breakage (HP:0040012)2.47073620
33Intrahepatic cholestasis (HP:0001406)2.44762154
34Progressive inability to walk (HP:0002505)2.43160538
35Abnormality of chromosome stability (HP:0003220)2.42921978
36Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.42774547
37Abnormal protein N-linked glycosylation (HP:0012347)2.42774547
38Abnormal protein glycosylation (HP:0012346)2.42774547
39Abnormal glycosylation (HP:0012345)2.42774547
40Abnormality of monocarboxylic acid metabolism (HP:0010996)2.40133029
41Increased serum lactate (HP:0002151)2.38025042
42Entropion (HP:0000621)2.35802719
43Rhabdomyolysis (HP:0003201)2.32414690
44Hyperglycinemia (HP:0002154)2.32253180
45Rough bone trabeculation (HP:0100670)2.30508529
46Atrophy/Degeneration involving motor neurons (HP:0007373)2.29062538
47Shoulder girdle muscle weakness (HP:0003547)2.26646494
48Abnormal hair whorl (HP:0010721)2.25378746
49Basal cell carcinoma (HP:0002671)2.23994940
50Abnormality of the calcaneus (HP:0008364)2.23318702
51Abnormality of the heme biosynthetic pathway (HP:0010472)2.23056801
52Petechiae (HP:0000967)2.22664937
53Abnormality of the preputium (HP:0100587)2.18973932
54Spastic diplegia (HP:0001264)2.18755673
55Upper limb muscle weakness (HP:0003484)2.18422172
56IgA deficiency (HP:0002720)2.17918451
57Nephroblastoma (Wilms tumor) (HP:0002667)2.17761436
58Medulloblastoma (HP:0002885)2.17565186
59Premature ovarian failure (HP:0008209)2.17535071
60Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.17104612
61Decreased activity of mitochondrial respiratory chain (HP:0008972)2.17104612
62Exercise-induced muscle cramps (HP:0003710)2.16720669
63Type I transferrin isoform profile (HP:0003642)2.16534144
64Bone marrow hypocellularity (HP:0005528)2.16086677
65Cerebral hypomyelination (HP:0006808)2.16070875
66Chromosomal breakage induced by crosslinking agents (HP:0003221)2.15795309
67Secondary amenorrhea (HP:0000869)2.15006811
68Squamous cell carcinoma (HP:0002860)2.12607333
69Volvulus (HP:0002580)2.12516531
70Cellular immunodeficiency (HP:0005374)2.11093267
71Irregular epiphyses (HP:0010582)2.10960469
72Nausea (HP:0002018)2.09592464
73Acute hepatic failure (HP:0006554)2.07661042
74Impaired proprioception (HP:0010831)2.07193097
75Embryonal renal neoplasm (HP:0011794)2.06675023
76Hypoglycemic coma (HP:0001325)2.06225565
77Increased serum pyruvate (HP:0003542)2.05181559
78Abnormality of glycolysis (HP:0004366)2.05181559
79Abnormal spermatogenesis (HP:0008669)2.05110276
80Generalized aminoaciduria (HP:0002909)2.04386905
81Acanthocytosis (HP:0001927)2.03548989
82Nemaline bodies (HP:0003798)2.01851905
83Pallor (HP:0000980)2.00805781
84Biliary tract neoplasm (HP:0100574)2.00340903
85Lactic acidosis (HP:0003128)1.99821688
86Premature graying of hair (HP:0002216)1.99764830
87Postnatal microcephaly (HP:0005484)1.98900974
88Hepatic necrosis (HP:0002605)1.97919651
89Upper motor neuron abnormality (HP:0002127)1.95982168
90Deviation of the thumb (HP:0009603)1.94331548
91Rimmed vacuoles (HP:0003805)1.93750651
92Cortical dysplasia (HP:0002539)1.93443790
93Megaloblastic anemia (HP:0001889)1.93301355
94Abnormal platelet volume (HP:0011876)1.92723879
95Proximal placement of thumb (HP:0009623)1.92445015
96Abnormal cartilage morphology (HP:0002763)1.92385665
97Horseshoe kidney (HP:0000085)1.92323840
98Pelvic girdle muscle weakness (HP:0003749)1.91835048
99Abnormal platelet function (HP:0011869)1.91284428
100Impaired platelet aggregation (HP:0003540)1.91284428
101Cutaneous melanoma (HP:0012056)1.91094412
102Neoplasm of the pancreas (HP:0002894)1.90725823
103Glossoptosis (HP:0000162)1.90660500
104Abnormality of serum amino acid levels (HP:0003112)1.90218705
105Hypolipoproteinemia (HP:0010981)1.90215239
106Macrocytic anemia (HP:0001972)1.90000140
107Microretrognathia (HP:0000308)1.89937306
108Methylmalonic acidemia (HP:0002912)1.88993030
109Poikilocytosis (HP:0004447)1.88985701
110Increased CSF lactate (HP:0002490)1.88785019
111Absent thumb (HP:0009777)1.88730628
112Sloping forehead (HP:0000340)1.88124701
113Ependymoma (HP:0002888)1.86598910
114Tongue fasciculations (HP:0001308)1.86429113
115Combined immunodeficiency (HP:0005387)1.85510234
116Hyperglycinuria (HP:0003108)1.82828360
117Abnormal biliary tract morphology (HP:0012440)1.82753133
118Trismus (HP:0000211)1.82743962
119Prolonged bleeding time (HP:0003010)1.82454115
120Meckel diverticulum (HP:0002245)1.80915722
121Abnormal mitochondria in muscle tissue (HP:0008316)1.80904974
122Increased intramyocellular lipid droplets (HP:0012240)1.80549874
123Hepatocellular necrosis (HP:0001404)1.80445395
124Amaurosis fugax (HP:0100576)1.79632730
125Acute encephalopathy (HP:0006846)1.79313277
126Abnormality of iron homeostasis (HP:0011031)1.79048122
127Poikiloderma (HP:0001029)1.78361750
128Pancytopenia (HP:0001876)1.77537307
129Abnormality of lateral ventricle (HP:0030047)1.77180131
130T lymphocytopenia (HP:0005403)1.76461319
131Muscle fiber inclusion bodies (HP:0100299)1.75976732
132Abnormality of the labia minora (HP:0012880)1.74872625
133Prominent nose (HP:0000448)1.74629120
134Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.74610435
135Tetraparesis (HP:0002273)1.74461006
136Lymphoma (HP:0002665)1.74364181
137Abnormality of T cells (HP:0002843)1.74245524
138Abnormality of alanine metabolism (HP:0010916)1.73822130
139Hyperalaninemia (HP:0003348)1.73822130
140Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.73822130
141Recurrent viral infections (HP:0004429)1.73529803
142Small intestinal stenosis (HP:0012848)1.73222859
143Duodenal stenosis (HP:0100867)1.73222859
144Exercise intolerance (HP:0003546)1.72226322
145Neoplasm of the colon (HP:0100273)1.71870283
146Abnormality of reticulocytes (HP:0004312)1.71580442
147Abnormality of glycine metabolism (HP:0010895)1.71198159
148Abnormality of serine family amino acid metabolism (HP:0010894)1.71198159
149Increased IgM level (HP:0003496)1.70390559
150Increased mean platelet volume (HP:0011877)1.69216487
151Recurrent abscess formation (HP:0002722)1.68650653
152Abnormality of methionine metabolism (HP:0010901)1.68552771
153Pancreatic islet-cell hyperplasia (HP:0004510)1.68201008
154Abnormality of transition element cation homeostasis (HP:0011030)1.67881252
155Missing ribs (HP:0000921)1.67651515
156Acute myeloid leukemia (HP:0004808)1.67493745
157Abnormal foot bone ossification (HP:0010675)1.67341501
158Abnormality of the ileum (HP:0001549)1.66863920
159Prolonged partial thromboplastin time (HP:0003645)1.66517372
160Abnormality of the hip-girdle musculature (HP:0001445)1.66163883
161Abnormality of the musculature of the pelvis (HP:0001469)1.66163883
162Metaphyseal cupping (HP:0003021)1.66069219
163Abnormality of T cell number (HP:0011839)1.65985252
164Facial hemangioma (HP:0000329)1.65832030
165Hyperammonemia (HP:0001987)1.63444892
166Abnormality of sulfur amino acid metabolism (HP:0004339)1.62252129

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB13.75954790
2CDC73.50694942
3EIF2AK13.43274179
4ACVR1B3.41308107
5NEK13.32579543
6NEK23.16454866
7WEE13.05706329
8TRIM282.72571859
9MST42.66634334
10SRPK12.49127966
11PLK42.23297723
12NUAK12.11905905
13NME12.09868065
14TTK2.02178205
15PBK1.90740052
16PKN21.85222987
17NME21.82436538
18EIF2AK31.82295188
19PDK21.80261124
20PLK11.76934417
21MKNK11.72790880
22AURKB1.71315468
23RPS6KA41.64262318
24BRSK21.63790316
25VRK11.58212963
26SIK31.56881137
27PLK31.56824892
28TGFBR11.53889503
29RPS6KB21.48301930
30IRAK31.46099905
31ERBB31.42705906
32ATR1.41835808
33TSSK61.39181350
34DYRK31.38124078
35VRK21.34527696
36STK101.33064707
37PASK1.32927093
38MAP2K31.32656312
39CDK71.26852056
40FLT31.26311950
41FGFR41.25804963
42TESK21.25455761
43MAP3K81.24821565
44SCYL21.24584090
45CDK41.23068283
46JAK31.22606375
47MKNK21.21670127
48EEF2K1.20387577
49STK41.17434326
50STK161.17379533
51MAP4K11.17187383
52TAF11.15916293
53CHEK21.15044865
54CDK121.13252286
55TLK11.12543905
56SMG11.05999817
57CHEK11.05722713
58ZAK1.04895540
59AURKA1.02987941
60BRD41.01167361
61BCR0.99940188
62MAP3K30.99140148
63KIT0.96905281
64MAPKAPK30.94923518
65TYK20.92120029
66PIM10.91634741
67PRPF4B0.91537466
68STK30.90648048
69TXK0.89224169
70STK240.87703624
71RAF10.86523969
72ATM0.81187345
73CDK60.78990670
74ERBB40.78404275
75BRSK10.78238055
76PAK40.76287247
77EPHA20.76082412
78MAP3K60.74759374
79IRAK40.74444600
80CDK190.73675691
81MAP3K140.72540565
82CDK20.72296026
83CCNB10.70627375
84FGFR30.70391752
85OBSCN0.69922148
86CLK10.68809185
87MELK0.68234519
88EIF2AK20.67732328
89MAPK110.64343217
90CSNK2A20.63587773
91MATK0.62209077
92CSNK1G30.61627082
93MAP3K100.61572637
94IRAK10.61126999
95MAP3K50.60908195
96BLK0.59872758
97STK38L0.58875338
98PIM20.58775711
99NEK90.57663436
100BCKDK0.57601648
101CSNK2A10.57590031
102TEC0.57486744
103IKBKE0.56823984
104PIK3CG0.56612416
105RPS6KA50.55821497
106IKBKB0.55293510
107TBK10.55141676
108CSNK1A1L0.53792896
109CDK90.52336102
110GRK60.52238553
111ZAP700.51703585
112ALK0.51531116
113CDK10.50793594
114MAP4K20.50272960
115FGR0.46863465
116CDK80.42955265
117BTK0.40532405
118MAP3K120.40341924
119BMPR20.40043466
120PAK10.39381819
121BMPR1B0.38585142
122CHUK0.38529980
123PRKCI0.37834850
124CSNK1G10.37171029
125AKT20.36378889
126IRAK20.35838713
127RPS6KB10.34728158
128LRRK20.33888902
129KDR0.33300366
130FGFR10.33037320
131SYK0.32042769
132CSNK1G20.31628319
133TAOK20.31462776
134RIPK40.31136518
135MARK30.30990196
136MTOR0.30656693
137BRAF0.29390929

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.98884591
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.52192301
3Mismatch repair_Homo sapiens_hsa034303.42403997
4One carbon pool by folate_Homo sapiens_hsa006703.32304591
5RNA polymerase_Homo sapiens_hsa030202.88145751
6Proteasome_Homo sapiens_hsa030502.84648511
7RNA transport_Homo sapiens_hsa030132.79389144
8Spliceosome_Homo sapiens_hsa030402.68098588
9Base excision repair_Homo sapiens_hsa034102.64453882
10Ribosome_Homo sapiens_hsa030102.37615297
11Cell cycle_Homo sapiens_hsa041102.34626115
12Nucleotide excision repair_Homo sapiens_hsa034202.24964759
13Homologous recombination_Homo sapiens_hsa034402.24085824
14Pyrimidine metabolism_Homo sapiens_hsa002402.23525088
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.10392725
16Non-homologous end-joining_Homo sapiens_hsa034501.90657191
17RNA degradation_Homo sapiens_hsa030181.84115576
18Fatty acid elongation_Homo sapiens_hsa000621.72326402
19Selenocompound metabolism_Homo sapiens_hsa004501.65022578
20Steroid biosynthesis_Homo sapiens_hsa001001.53904959
21Cysteine and methionine metabolism_Homo sapiens_hsa002701.52913662
22Fanconi anemia pathway_Homo sapiens_hsa034601.51431030
23Basal transcription factors_Homo sapiens_hsa030221.47573320
24Systemic lupus erythematosus_Homo sapiens_hsa053221.44741964
25Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.43789011
26mRNA surveillance pathway_Homo sapiens_hsa030151.42731999
27p53 signaling pathway_Homo sapiens_hsa041151.39395246
28Biosynthesis of amino acids_Homo sapiens_hsa012301.36697838
29Vitamin B6 metabolism_Homo sapiens_hsa007501.31369742
30Drug metabolism - other enzymes_Homo sapiens_hsa009831.29770522
31Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.29292877
32Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.26637446
332-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.17845927
34Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.17232056
35Protein export_Homo sapiens_hsa030601.17140156
36Epstein-Barr virus infection_Homo sapiens_hsa051691.11036237
37Herpes simplex infection_Homo sapiens_hsa051681.10642949
38Primary bile acid biosynthesis_Homo sapiens_hsa001201.04795334
39Folate biosynthesis_Homo sapiens_hsa007901.03251858
40Carbon metabolism_Homo sapiens_hsa012001.01038469
41Antigen processing and presentation_Homo sapiens_hsa046120.98090525
42Cyanoamino acid metabolism_Homo sapiens_hsa004600.96125082
43Sulfur relay system_Homo sapiens_hsa041220.95964761
44Purine metabolism_Homo sapiens_hsa002300.95861272
45Pentose phosphate pathway_Homo sapiens_hsa000300.94855933
46Viral carcinogenesis_Homo sapiens_hsa052030.92502467
47Caffeine metabolism_Homo sapiens_hsa002320.92068624
48Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.91712830
49Shigellosis_Homo sapiens_hsa051310.87174435
50Legionellosis_Homo sapiens_hsa051340.85089726
51Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.84745051
52Fatty acid metabolism_Homo sapiens_hsa012120.81972250
53Sulfur metabolism_Homo sapiens_hsa009200.81245068
54Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.70873869
55Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.68880209
56Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.68279276
57Parkinsons disease_Homo sapiens_hsa050120.67874064
58Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.66544043
59Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.61323556
60Thyroid cancer_Homo sapiens_hsa052160.60941190
61Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.57761286
62Oocyte meiosis_Homo sapiens_hsa041140.54492340
63Small cell lung cancer_Homo sapiens_hsa052220.54020377
64HTLV-I infection_Homo sapiens_hsa051660.53837515
65Primary immunodeficiency_Homo sapiens_hsa053400.52778389
66Glutathione metabolism_Homo sapiens_hsa004800.52640293
67Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.52310032
68NF-kappa B signaling pathway_Homo sapiens_hsa040640.51165452
69Measles_Homo sapiens_hsa051620.50981413
70Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.50858019
71MicroRNAs in cancer_Homo sapiens_hsa052060.49483905
72N-Glycan biosynthesis_Homo sapiens_hsa005100.48832848
73SNARE interactions in vesicular transport_Homo sapiens_hsa041300.48791638
74Viral myocarditis_Homo sapiens_hsa054160.48145942
75Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.46480503
76Fructose and mannose metabolism_Homo sapiens_hsa000510.46105751
77Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.45659637
78Propanoate metabolism_Homo sapiens_hsa006400.45235143
79Peroxisome_Homo sapiens_hsa041460.45110057
80Arginine biosynthesis_Homo sapiens_hsa002200.44846471
81Pyruvate metabolism_Homo sapiens_hsa006200.44493693
82Regulation of autophagy_Homo sapiens_hsa041400.43059178
83Asthma_Homo sapiens_hsa053100.42520358
84Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.42024515
85Fatty acid degradation_Homo sapiens_hsa000710.41902317
86Vitamin digestion and absorption_Homo sapiens_hsa049770.40398186
87Hepatitis B_Homo sapiens_hsa051610.39808088
88Complement and coagulation cascades_Homo sapiens_hsa046100.36837314
89Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.36419525
90Lysine degradation_Homo sapiens_hsa003100.35562870
91Huntingtons disease_Homo sapiens_hsa050160.35524806
92Apoptosis_Homo sapiens_hsa042100.35185320
93Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.34510740
94B cell receptor signaling pathway_Homo sapiens_hsa046620.33754046
95Hematopoietic cell lineage_Homo sapiens_hsa046400.33514877
96Tryptophan metabolism_Homo sapiens_hsa003800.33279712
97Influenza A_Homo sapiens_hsa051640.32758287
98TGF-beta signaling pathway_Homo sapiens_hsa043500.32485663
99Galactose metabolism_Homo sapiens_hsa000520.31125081
100Oxidative phosphorylation_Homo sapiens_hsa001900.31064886
101Transcriptional misregulation in cancer_Homo sapiens_hsa052020.30939440
102Sphingolipid metabolism_Homo sapiens_hsa006000.29107503
103beta-Alanine metabolism_Homo sapiens_hsa004100.27671251
104Intestinal immune network for IgA production_Homo sapiens_hsa046720.27214463
105Pentose and glucuronate interconversions_Homo sapiens_hsa000400.27047787
106Starch and sucrose metabolism_Homo sapiens_hsa005000.26721859
107Metabolic pathways_Homo sapiens_hsa011000.26105352
108Toll-like receptor signaling pathway_Homo sapiens_hsa046200.26006218
109Arginine and proline metabolism_Homo sapiens_hsa003300.25331163
110Tuberculosis_Homo sapiens_hsa051520.24947547
111Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.24678904
112Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.24414229
113Acute myeloid leukemia_Homo sapiens_hsa052210.24331098
114RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.23640068
115Graft-versus-host disease_Homo sapiens_hsa053320.22286394
116Leishmaniasis_Homo sapiens_hsa051400.22220665
117Pancreatic cancer_Homo sapiens_hsa052120.20145571
118Alcoholism_Homo sapiens_hsa050340.18838905
119NOD-like receptor signaling pathway_Homo sapiens_hsa046210.18650791
120Notch signaling pathway_Homo sapiens_hsa043300.17931705
121Allograft rejection_Homo sapiens_hsa053300.17726052

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