FAT3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.63675409
2positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.34216177
3locomotory exploration behavior (GO:0035641)5.17714546
4regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.17363002
5vocalization behavior (GO:0071625)5.14228638
6protein localization to synapse (GO:0035418)4.92359025
7neuron cell-cell adhesion (GO:0007158)4.83068219
8positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.79355854
9synaptic vesicle maturation (GO:0016188)4.78037140
10regulation of glutamate receptor signaling pathway (GO:1900449)4.76105617
11synaptic vesicle exocytosis (GO:0016079)4.70697351
12ionotropic glutamate receptor signaling pathway (GO:0035235)4.62730247
13synaptic vesicle docking involved in exocytosis (GO:0016081)4.59570380
14regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.52729518
15pyrimidine nucleobase catabolic process (GO:0006208)4.51940612
16neuronal action potential propagation (GO:0019227)4.41120531
17synaptic transmission, glutamatergic (GO:0035249)4.38062123
18membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.36926994
19glutamate secretion (GO:0014047)4.35748614
20limb bud formation (GO:0060174)4.31890475
21regulation of synaptic vesicle exocytosis (GO:2000300)4.31088487
22glutamate receptor signaling pathway (GO:0007215)4.27215874
23regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.27131494
24dendritic spine morphogenesis (GO:0060997)4.25684030
25neurotransmitter-gated ion channel clustering (GO:0072578)4.25323601
26regulation of long-term neuronal synaptic plasticity (GO:0048169)4.21026668
27neuron-neuron synaptic transmission (GO:0007270)4.16937435
28exploration behavior (GO:0035640)4.16312176
29regulation of synapse structural plasticity (GO:0051823)4.13607087
30axonal fasciculation (GO:0007413)4.07440041
31regulation of neuronal synaptic plasticity (GO:0048168)4.04418628
32layer formation in cerebral cortex (GO:0021819)3.99541561
33neuron recognition (GO:0008038)3.96931763
34neurotransmitter secretion (GO:0007269)3.79752480
35regulation of synaptic vesicle transport (GO:1902803)3.75816856
36regulation of excitatory postsynaptic membrane potential (GO:0060079)3.74841863
37regulation of postsynaptic membrane potential (GO:0060078)3.69156810
38cerebellar Purkinje cell differentiation (GO:0021702)3.69001192
39negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.61442931
40innervation (GO:0060384)3.61006183
41auditory behavior (GO:0031223)3.60895403
42regulation of synaptic transmission, glutamatergic (GO:0051966)3.60245327
43presynaptic membrane assembly (GO:0097105)3.59384269
44postsynaptic membrane organization (GO:0001941)3.58763888
45long-term memory (GO:0007616)3.56733417
46response to auditory stimulus (GO:0010996)3.55001807
47cellular potassium ion homeostasis (GO:0030007)3.52861546
48neuronal stem cell maintenance (GO:0097150)3.52011314
49central nervous system neuron axonogenesis (GO:0021955)3.51774124
50G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.51735422
51nucleobase catabolic process (GO:0046113)3.49493090
52positive regulation of synapse maturation (GO:0090129)3.48189707
53gamma-aminobutyric acid transport (GO:0015812)3.47625067
54positive regulation of membrane potential (GO:0045838)3.45260634
55positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.44491010
56membrane hyperpolarization (GO:0060081)3.40407756
57dendrite morphogenesis (GO:0048813)3.40296237
58response to histamine (GO:0034776)3.40023812
59regulation of dendritic spine morphogenesis (GO:0061001)3.39486853
60membrane depolarization during action potential (GO:0086010)3.38493203
61positive regulation of synaptic transmission, GABAergic (GO:0032230)3.36125014
62regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.34440085
63prepulse inhibition (GO:0060134)3.32186082
64positive regulation of dendritic spine morphogenesis (GO:0061003)3.32186008
65presynaptic membrane organization (GO:0097090)3.31804894
66startle response (GO:0001964)3.28106067
67regulation of synaptic plasticity (GO:0048167)3.26486217
68transmission of nerve impulse (GO:0019226)3.25521238
69proline transport (GO:0015824)3.25327116
70behavioral defense response (GO:0002209)3.24588884
71behavioral fear response (GO:0001662)3.24588884
72neuronal ion channel clustering (GO:0045161)3.24329243
73membrane depolarization (GO:0051899)3.23922370
74activation of protein kinase A activity (GO:0034199)3.21974499
75synaptic vesicle endocytosis (GO:0048488)3.20862802
76retinal ganglion cell axon guidance (GO:0031290)3.20847453
77neuromuscular process controlling balance (GO:0050885)3.20741325
78establishment of nucleus localization (GO:0040023)3.18572861
79gamma-aminobutyric acid signaling pathway (GO:0007214)3.16980371
80synapse assembly (GO:0007416)3.15954551
81cell migration in hindbrain (GO:0021535)3.14228062
82regulation of axon guidance (GO:1902667)3.12709609
83central nervous system projection neuron axonogenesis (GO:0021952)3.12026086
84mechanosensory behavior (GO:0007638)3.11269350
85positive regulation of synapse assembly (GO:0051965)3.10422492
86negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.09213929
87negative regulation of translation, ncRNA-mediated (GO:0040033)3.09213929
88regulation of translation, ncRNA-mediated (GO:0045974)3.09213929
89retinal rod cell development (GO:0046548)3.08985305
90long-term synaptic potentiation (GO:0060291)3.08882592
91positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.08681553
92positive regulation of neurotransmitter secretion (GO:0001956)3.08349885
93neurotransmitter transport (GO:0006836)3.06899584
94membrane assembly (GO:0071709)3.05857171
95regulation of neurotransmitter secretion (GO:0046928)3.03295745
96learning (GO:0007612)3.02129143
97retinal cone cell development (GO:0046549)3.01450722
98positive regulation of neurotransmitter transport (GO:0051590)3.01037662
99negative regulation of cytosolic calcium ion concentration (GO:0051481)3.00704055
100fear response (GO:0042596)3.00012800
101negative regulation of astrocyte differentiation (GO:0048712)2.99385509
102regulation of dendritic spine development (GO:0060998)2.97130762
103dendritic spine organization (GO:0097061)2.96781063
104sodium ion export (GO:0071436)2.96437199
105atrial cardiac muscle cell action potential (GO:0086014)2.95121118
106cerebral cortex radially oriented cell migration (GO:0021799)2.93868571
107behavioral response to cocaine (GO:0048148)2.93779300
108cerebellar granule cell differentiation (GO:0021707)2.89462840
109regulation of neurotransmitter levels (GO:0001505)2.89014001
110G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.88893952
111neuromuscular process (GO:0050905)2.88041597
112negative regulation of synaptic transmission, GABAergic (GO:0032229)2.87290082
113striatum development (GO:0021756)2.86717340
114regulation of synapse assembly (GO:0051963)2.85408520
115neuronal action potential (GO:0019228)2.84635180
116synapse organization (GO:0050808)2.84410244
117cochlea development (GO:0090102)2.83582682
118regulation of respiratory system process (GO:0044065)2.83573466
119nerve growth factor signaling pathway (GO:0038180)2.83451799
120vesicle transport along microtubule (GO:0047496)2.82210362
121regulation of neurotransmitter transport (GO:0051588)2.82177656
122otic vesicle formation (GO:0030916)2.81187544
123heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157)2.76184194
124nucleus localization (GO:0051647)2.75661677
125negative chemotaxis (GO:0050919)2.74489198
126limb development (GO:0060173)2.71219983
127appendage development (GO:0048736)2.71219983
128lateral sprouting from an epithelium (GO:0060601)2.70539582
129regulation of axon extension involved in axon guidance (GO:0048841)2.70480012
130negative regulation of axon guidance (GO:1902668)2.69462130
131dermatan sulfate biosynthetic process (GO:0030208)2.69184373
132spinal cord development (GO:0021510)2.68167602
133axonogenesis (GO:0007409)2.65883632
134calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.65586369
135somite development (GO:0061053)2.64852353
136cellular response to cholesterol (GO:0071397)2.64597833
137neuron projection extension involved in neuron projection guidance (GO:1902284)2.63222226
138axon extension involved in axon guidance (GO:0048846)2.63222226
139axon ensheathment in central nervous system (GO:0032291)2.60842839
140central nervous system myelination (GO:0022010)2.60842839
141establishment of mitochondrion localization (GO:0051654)2.59958993
142* neuron migration (GO:0001764)2.56503995
143hindbrain development (GO:0030902)2.52320247
144cerebral cortex cell migration (GO:0021795)2.45181726
145artery development (GO:0060840)2.43497337
146regulation of non-canonical Wnt signaling pathway (GO:2000050)2.43086284
147regulation of synapse organization (GO:0050807)2.42516985
148axon extension (GO:0048675)2.42466651
149positive regulation of dendrite morphogenesis (GO:0050775)2.41298855
150adult walking behavior (GO:0007628)2.40335605
151regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.39903529
152neuron fate determination (GO:0048664)2.39153185
153negative regulation of glial cell differentiation (GO:0045686)2.38300490
154inner ear receptor cell development (GO:0060119)2.38012866
155dorsal/ventral axis specification (GO:0009950)2.36685008

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.79384081
2* GBX2_23144817_ChIP-Seq_PC3_Human4.04250528
3JARID2_20064375_ChIP-Seq_MESCs_Mouse3.01381925
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.01155455
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.98265283
6HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.93071158
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.63963530
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.63963530
9ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.56248983
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.54225047
11* EZH2_27304074_Chip-Seq_ESCs_Mouse2.54155717
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.53330249
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.52623090
14EED_16625203_ChIP-ChIP_MESCs_Mouse2.46368738
15REST_21632747_ChIP-Seq_MESCs_Mouse2.36828977
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.35791571
17MTF2_20144788_ChIP-Seq_MESCs_Mouse2.31947107
18GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.30263777
19* DROSHA_22980978_ChIP-Seq_HELA_Human2.29018454
20RBPJ_22232070_ChIP-Seq_NCS_Mouse2.27635441
21SALL1_21062744_ChIP-ChIP_HESCs_Human2.25721513
22SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.24210524
23RARB_27405468_Chip-Seq_BRAIN_Mouse2.23035690
24* RNF2_27304074_Chip-Seq_ESCs_Mouse2.19699937
25SUZ12_27294783_Chip-Seq_ESCs_Mouse2.07819564
26EZH2_27294783_Chip-Seq_ESCs_Mouse2.05559734
27* CTBP2_25329375_ChIP-Seq_LNCAP_Human2.02124812
28TAF15_26573619_Chip-Seq_HEK293_Human2.01980318
29AR_21572438_ChIP-Seq_LNCaP_Human2.00093944
30* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.93162278
31CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.86562580
32REST_18959480_ChIP-ChIP_MESCs_Mouse1.84982385
33* CTBP1_25329375_ChIP-Seq_LNCAP_Human1.82908025
34* SMAD4_21799915_ChIP-Seq_A2780_Human1.76854230
35ZFP57_27257070_Chip-Seq_ESCs_Mouse1.74738055
36MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.73303261
37EWS_26573619_Chip-Seq_HEK293_Human1.72916889
38PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.71288275
39RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.69660818
40NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.67323603
41ZNF274_21170338_ChIP-Seq_K562_Hela1.66365014
42* P300_19829295_ChIP-Seq_ESCs_Human1.63919095
43POU5F1_16153702_ChIP-ChIP_HESCs_Human1.60419603
44PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.56539681
45EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.54232915
46IKZF1_21737484_ChIP-ChIP_HCT116_Human1.48488789
47* CBX2_27304074_Chip-Seq_ESCs_Mouse1.48389316
48* SMAD3_21741376_ChIP-Seq_EPCs_Human1.48212723
49* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.45056504
50MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.44721084
51CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.43282166
52PIAS1_25552417_ChIP-Seq_VCAP_Human1.41310975
53GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.39873112
54SOX2_21211035_ChIP-Seq_LN229_Gbm1.39578807
55ERG_21242973_ChIP-ChIP_JURKAT_Human1.39440505
56* STAT3_23295773_ChIP-Seq_U87_Human1.38675981
57IGF1R_20145208_ChIP-Seq_DFB_Human1.37879244
58OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.37674254
59POU3F2_20337985_ChIP-ChIP_501MEL_Human1.35776293
60TOP2B_26459242_ChIP-Seq_MCF-7_Human1.32924133
61VDR_22108803_ChIP-Seq_LS180_Human1.32862154
62ARNT_22903824_ChIP-Seq_MCF-7_Human1.32681895
63* AR_25329375_ChIP-Seq_VCAP_Human1.32347488
64AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.32278897
65RING1B_27294783_Chip-Seq_ESCs_Mouse1.31529086
66ZNF217_24962896_ChIP-Seq_MCF-7_Human1.30705589
67TP53_16413492_ChIP-PET_HCT116_Human1.30123821
68STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.29026727
69AHR_22903824_ChIP-Seq_MCF-7_Human1.28914738
70* NR3C1_23031785_ChIP-Seq_PC12_Mouse1.27933468
71AR_19668381_ChIP-Seq_PC3_Human1.27438972
72BMI1_23680149_ChIP-Seq_NPCS_Mouse1.26945824
73* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26768335
74* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.25814015
75TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.23348426
76CDX2_19796622_ChIP-Seq_MESCs_Mouse1.22976043
77CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.22935307
78* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.22916651
79SMAD_19615063_ChIP-ChIP_OVARY_Human1.22708715
80FUS_26573619_Chip-Seq_HEK293_Human1.21890670
81KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.21502626
82RNF2_27304074_Chip-Seq_NSC_Mouse1.20529868
83* TCF4_23295773_ChIP-Seq_U87_Human1.19685586
84* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.18528527
85RING1B_27294783_Chip-Seq_NPCs_Mouse1.17717594
86IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.16977491
87CBP_20019798_ChIP-Seq_JUKART_Human1.16977491
88KDM2B_26808549_Chip-Seq_REH_Human1.15093645
89TBX3_20139965_ChIP-Seq_MESCs_Mouse1.15022572
90TBX3_20139965_ChIP-Seq_ESCs_Mouse1.14348714
91BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.13337112
92FLI1_27457419_Chip-Seq_LIVER_Mouse1.11827315
93HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.10414606
94P53_22127205_ChIP-Seq_FIBROBLAST_Human1.09401332
95* NR3C1_21868756_ChIP-Seq_MCF10A_Human1.09358154
96TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.07893117
97EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.06796436
98TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06654810
99POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.06654810
100* RUNX2_22187159_ChIP-Seq_PCA_Human1.05868825
101UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.05761329
102TAL1_26923725_Chip-Seq_HPCs_Mouse1.04665508
103VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.04649122
104TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.04195751
105* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.02796302
106CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00952868
107RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.99418447
108NANOG_18555785_Chip-Seq_ESCs_Mouse0.98819426
109TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.98718691
110WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.98249825
111BCAT_22108803_ChIP-Seq_LS180_Human0.98047361
112* PRDM14_20953172_ChIP-Seq_ESCs_Human0.98005872
113* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97434217
114* SMAD3_21741376_ChIP-Seq_ESCs_Human0.97096743
115TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.96299193
116MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.96014812
117* TP53_18474530_ChIP-ChIP_U2OS_Human0.94378435
118ER_23166858_ChIP-Seq_MCF-7_Human0.93209333
119RXR_22108803_ChIP-Seq_LS180_Human0.92122958
120SMAD3_21741376_ChIP-Seq_HESCs_Human0.91492715
121SOX9_26525672_Chip-Seq_HEART_Mouse0.91325311

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.05513462
2MP0003880_abnormal_central_pattern4.90805100
3MP0003635_abnormal_synaptic_transmissio3.96796100
4MP0004270_analgesia3.65033423
5MP0002063_abnormal_learning/memory/cond3.30477634
6MP0009745_abnormal_behavioral_response3.21416084
7MP0009046_muscle_twitch3.00241492
8MP0002064_seizures2.96520752
9MP0005423_abnormal_somatic_nervous2.86530675
10MP0001968_abnormal_touch/_nociception2.82595369
11MP0002572_abnormal_emotion/affect_behav2.79692328
12MP0001486_abnormal_startle_reflex2.67318875
13MP0000566_synostosis2.65812847
14MP0002822_catalepsy2.54668117
15MP0002272_abnormal_nervous_system2.47210926
16MP0002734_abnormal_mechanical_nocicepti2.46797153
17MP0003136_yellow_coat_color2.38459150
18MP0000569_abnormal_digit_pigmentation2.26008221
19MP0000778_abnormal_nervous_system2.20208703
20MP0002735_abnormal_chemical_nociception2.14218091
21MP0002736_abnormal_nociception_after2.05858243
22MP0001501_abnormal_sleep_pattern2.01057443
23MP0002067_abnormal_sensory_capabilities1.99204813
24MP0002184_abnormal_innervation1.95960329
25MP0003890_abnormal_embryonic-extraembry1.91741378
26MP0002557_abnormal_social/conspecific_i1.88814155
27MP0001440_abnormal_grooming_behavior1.83610457
28MP0005646_abnormal_pituitary_gland1.80641969
29MP0005248_abnormal_Harderian_gland1.80346396
30MP0004924_abnormal_behavior1.76989913
31MP0005386_behavior/neurological_phenoty1.76989913
32MP0004811_abnormal_neuron_physiology1.75965075
33MP0002733_abnormal_thermal_nociception1.75420074
34MP0009780_abnormal_chondrocyte_physiolo1.73914222
35MP0004858_abnormal_nervous_system1.71524726
36MP0006276_abnormal_autonomic_nervous1.68707446
37MP0001970_abnormal_pain_threshold1.68564673
38MP0003122_maternal_imprinting1.66740279
39MP0000955_abnormal_spinal_cord1.66334640
40MP0003787_abnormal_imprinting1.64029006
41MP0000537_abnormal_urethra_morphology1.61430506
42MP0001529_abnormal_vocalization1.60483262
43MP0008569_lethality_at_weaning1.59699349
44MP0001346_abnormal_lacrimal_gland1.57966701
45MP0003937_abnormal_limbs/digits/tail_de1.56880088
46MP0003119_abnormal_digestive_system1.53801642
47MP0002882_abnormal_neuron_morphology1.53115608
48MP0002102_abnormal_ear_morphology1.51822456
49MP0001293_anophthalmia1.51013849
50MP0001984_abnormal_olfaction1.50765826
51MP0002234_abnormal_pharynx_morphology1.48529856
52MP0005645_abnormal_hypothalamus_physiol1.46363048
53MP0006292_abnormal_olfactory_placode1.44884829
54MP0002909_abnormal_adrenal_gland1.44556689
55MP0003879_abnormal_hair_cell1.40591175
56MP0002697_abnormal_eye_size1.40274480
57MP0001188_hyperpigmentation1.38936313
58MP0002066_abnormal_motor_capabilities/c1.36600579
59MP0005551_abnormal_eye_electrophysiolog1.31117876
60MP0004133_heterotaxia1.30382843
61MP0001502_abnormal_circadian_rhythm1.28244924
62MP0002152_abnormal_brain_morphology1.25440688
63MP0003633_abnormal_nervous_system1.24631756
64MP0001286_abnormal_eye_development1.23926920
65MP0003329_amyloid_beta_deposits1.21585300
66MP0002233_abnormal_nose_morphology1.20079390
67MP0004885_abnormal_endolymph1.19626174
68MP0002938_white_spotting1.18716948
69MP0001299_abnormal_eye_distance/1.16110904
70MP0002653_abnormal_ependyma_morphology1.15700499
71MP0000631_abnormal_neuroendocrine_gland1.15552832
72MP0010030_abnormal_orbit_morphology1.14782320
73MP0004742_abnormal_vestibular_system1.11403366
74MP0000428_abnormal_craniofacial_morphol1.10573697
75MP0005391_vision/eye_phenotype1.08805863
76MP0003631_nervous_system_phenotype1.06642570
77MP0000049_abnormal_middle_ear1.06611151
78MP0004142_abnormal_muscle_tone1.05142224
79MP0003283_abnormal_digestive_organ1.01544840
80MP0000462_abnormal_digestive_system0.98782340
81MP0002229_neurodegeneration0.96678013
82MP0001905_abnormal_dopamine_level0.96443107
83MP0001177_atelectasis0.95893647
84MP0003121_genomic_imprinting0.93268147
85MP0000383_abnormal_hair_follicle0.92400750
86MP0003385_abnormal_body_wall0.92132891
87MP0003755_abnormal_palate_morphology0.91687315
88MP0003935_abnormal_craniofacial_develop0.91472733
89MP0004145_abnormal_muscle_electrophysio0.91460817
90MP0002752_abnormal_somatic_nervous0.91256420
91MP0003634_abnormal_glial_cell0.90780093
92MP0009053_abnormal_anal_canal0.89207476
93MP0009250_abnormal_appendicular_skeleto0.89150548
94MP0002081_perinatal_lethality0.87704529
95MP0004085_abnormal_heartbeat0.87519361
96MP0000534_abnormal_ureter_morphology0.87053288
97MP0005171_absent_coat_pigmentation0.86966977
98MP0000751_myopathy0.86573217
99MP0000579_abnormal_nail_morphology0.85264306
100MP0005409_darkened_coat_color0.82887049
101MP0003861_abnormal_nervous_system0.82673274
102MP0002069_abnormal_eating/drinking_beha0.82219779
103MP0001963_abnormal_hearing_physiology0.82035910
104MP0005499_abnormal_olfactory_system0.81942246
105MP0005394_taste/olfaction_phenotype0.81942246
106MP0002092_abnormal_eye_morphology0.81154711
107MP0003137_abnormal_impulse_conducting0.81104566
108MP0002282_abnormal_trachea_morphology0.80730735
109MP0000647_abnormal_sebaceous_gland0.79784480
110MP0004233_abnormal_muscle_weight0.79214952
111MP0002249_abnormal_larynx_morphology0.78223237
112MP0003632_abnormal_nervous_system0.78136282
113MP0005253_abnormal_eye_physiology0.76139987
114MP0002090_abnormal_vision0.73189815
115MP0008961_abnormal_basal_metabolism0.73052106
116MP0006072_abnormal_retinal_apoptosis0.72779171
117MP0001943_abnormal_respiration0.71056255
118MP0008872_abnormal_physiological_respon0.70304933
119MP0008874_decreased_physiological_sensi0.69201772
120MP0003690_abnormal_glial_cell0.66948610
121MP0004215_abnormal_myocardial_fiber0.65609135
122MP0003942_abnormal_urinary_system0.65226225
123MP0001485_abnormal_pinna_reflex0.64345224
124MP0000026_abnormal_inner_ear0.63336100
125MP0005187_abnormal_penis_morphology0.61829143
126MP0010770_preweaning_lethality0.61415954
127MP0002082_postnatal_lethality0.61415954
128MP0010769_abnormal_survival0.59767559
129MP0010386_abnormal_urinary_bladder0.59682453
130MP0003938_abnormal_ear_development0.57913844
131MP0002638_abnormal_pupillary_reflex0.57395837
132MP0002751_abnormal_autonomic_nervous0.56791964
133MP0010768_mortality/aging0.55792676
134MP0000920_abnormal_myelination0.55554160
135MP0005195_abnormal_posterior_eye0.53705825
136MP0005623_abnormal_meninges_morphology0.53326033

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.20694263
2Myokymia (HP:0002411)5.81288617
3Focal seizures (HP:0007359)5.42009586
4Epileptic encephalopathy (HP:0200134)4.62249855
5Febrile seizures (HP:0002373)4.34595700
6Atonic seizures (HP:0010819)3.83596894
7Progressive cerebellar ataxia (HP:0002073)3.74798689
8Absence seizures (HP:0002121)3.69496061
9Hyperventilation (HP:0002883)3.64922773
10Visual hallucinations (HP:0002367)3.64841784
11Broad-based gait (HP:0002136)3.63215418
12Action tremor (HP:0002345)3.51411369
13Vitreoretinal degeneration (HP:0000655)3.41346422
14Dialeptic seizures (HP:0011146)3.37522599
15Generalized tonic-clonic seizures (HP:0002069)3.35636107
16Hepatoblastoma (HP:0002884)3.24911792
17Short 4th metacarpal (HP:0010044)3.13937863
18Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.13937863
19Impaired vibration sensation in the lower limbs (HP:0002166)3.05430550
20Gaze-evoked nystagmus (HP:0000640)3.02878591
21Truncal ataxia (HP:0002078)3.01458865
22Drooling (HP:0002307)2.97236236
23Excessive salivation (HP:0003781)2.97236236
24Urinary bladder sphincter dysfunction (HP:0002839)2.90933104
25Supranuclear gaze palsy (HP:0000605)2.88397896
26Dysdiadochokinesis (HP:0002075)2.86902063
27Poor eye contact (HP:0000817)2.86472963
28Aqueductal stenosis (HP:0002410)2.79971559
29Cutaneous syndactyly (HP:0012725)2.78826937
30Septo-optic dysplasia (HP:0100842)2.72928319
31Ankle clonus (HP:0011448)2.70759813
32Impaired smooth pursuit (HP:0007772)2.65763502
33Abnormal social behavior (HP:0012433)2.63721629
34Impaired social interactions (HP:0000735)2.63721629
35Epileptiform EEG discharges (HP:0011182)2.60876355
36Colon cancer (HP:0003003)2.59819524
37Amblyopia (HP:0000646)2.58948158
38Genetic anticipation (HP:0003743)2.55103817
39Depression (HP:0000716)2.52704659
40Dysmetria (HP:0001310)2.50171496
41Chorioretinal atrophy (HP:0000533)2.50153584
42Postural instability (HP:0002172)2.49389275
43Hemiparesis (HP:0001269)2.48446709
44Abnormality of the 4th metacarpal (HP:0010012)2.47443865
45Absent speech (HP:0001344)2.46341382
46Urinary urgency (HP:0000012)2.43369349
47EEG with generalized epileptiform discharges (HP:0011198)2.42546144
48Anophthalmia (HP:0000528)2.40640175
49Scanning speech (HP:0002168)2.37210099
50Papilledema (HP:0001085)2.37001053
51Papillary thyroid carcinoma (HP:0002895)2.34680362
52Termporal pattern (HP:0011008)2.34370862
53Insidious onset (HP:0003587)2.34370862
54Mutism (HP:0002300)2.34335370
55Abnormal eating behavior (HP:0100738)2.32289444
56Esophageal atresia (HP:0002032)2.32246991
57Aplasia/Hypoplasia of the sternum (HP:0006714)2.32073054
58Stereotypic behavior (HP:0000733)2.31572380
59Renal hypoplasia (HP:0000089)2.31131533
60Megalencephaly (HP:0001355)2.30809033
61Abnormality of ocular smooth pursuit (HP:0000617)2.29871800
62Hypsarrhythmia (HP:0002521)2.27045173
63Bilateral microphthalmos (HP:0007633)2.26381493
64Preaxial foot polydactyly (HP:0001841)2.26357480
65Chronic hepatic failure (HP:0100626)2.26078388
66Anxiety (HP:0000739)2.24467954
67Intestinal atresia (HP:0011100)2.22429960
68Protruding tongue (HP:0010808)2.19789083
69Inappropriate behavior (HP:0000719)2.18620926
70Genital tract atresia (HP:0001827)2.14884241
71Gastrointestinal atresia (HP:0002589)2.14241150
72Optic nerve hypoplasia (HP:0000609)2.14209314
73Vaginal atresia (HP:0000148)2.12329755
74Cupped ear (HP:0000378)2.12025996
75Blue irides (HP:0000635)2.11848463
76Alacrima (HP:0000522)2.11641995
77Diplopia (HP:0000651)2.10553176
78Abnormality of binocular vision (HP:0011514)2.10553176
79Exotropia (HP:0000577)2.10081704
80Spastic gait (HP:0002064)2.09897891
81Hemiplegia (HP:0002301)2.08500348
82Impaired vibratory sensation (HP:0002495)2.08453499
83Lissencephaly (HP:0001339)2.08184982
84Fetal akinesia sequence (HP:0001989)2.07280123
85Torticollis (HP:0000473)2.07036422
86Pheochromocytoma (HP:0002666)2.06878850
87True hermaphroditism (HP:0010459)2.06653354
88Bifid tongue (HP:0010297)2.06389186
89Split foot (HP:0001839)2.04482901
90Medulloblastoma (HP:0002885)2.02917108
91Dysmetric saccades (HP:0000641)2.02512021
92Lower limb muscle weakness (HP:0007340)1.97657506
93Intention tremor (HP:0002080)1.97276587
94Decreased lacrimation (HP:0000633)1.97188562
95Abnormality of the corticospinal tract (HP:0002492)1.95813489
96Abnormality of salivation (HP:0100755)1.95203962
97Volvulus (HP:0002580)1.95071241
98Bradykinesia (HP:0002067)1.94815518
99Neoplasm of the oral cavity (HP:0100649)1.93767066
100Limb dystonia (HP:0002451)1.92340394
101Progressive inability to walk (HP:0002505)1.90968253
102Neurofibrillary tangles (HP:0002185)1.90955496
103Pointed chin (HP:0000307)1.90954569
104Specific learning disability (HP:0001328)1.89552077
105Polyphagia (HP:0002591)1.89543060
106Abnormality of the septum pellucidum (HP:0007375)1.89408642
107Aplasia involving bones of the extremities (HP:0009825)1.89024427
108Aplasia involving bones of the upper limbs (HP:0009823)1.89024427
109Aplasia of the phalanges of the hand (HP:0009802)1.89024427
110Abnormality of the pubic bones (HP:0003172)1.88733621
111Cerebral inclusion bodies (HP:0100314)1.88409593
112Abnormality of the astrocytes (HP:0100707)1.87209061
113Astrocytoma (HP:0009592)1.87209061
114Central scotoma (HP:0000603)1.86617690
115Inability to walk (HP:0002540)1.85996600
116Glioma (HP:0009733)1.85604596
117Abnormality of the ischium (HP:0003174)1.85293475
118Macroorchidism (HP:0000053)1.84423422
119Pancreatic fibrosis (HP:0100732)1.84194783
120Stomach cancer (HP:0012126)1.84050269
121Bronchomalacia (HP:0002780)1.82577924
122Absent septum pellucidum (HP:0001331)1.81814527
123Generalized hypopigmentation of hair (HP:0011358)1.81599847
124Abnormality of the lower motor neuron (HP:0002366)1.81584507
125Focal dystonia (HP:0004373)1.81210072
126Nephronophthisis (HP:0000090)1.80477772
127Gait imbalance (HP:0002141)1.79053329
128Agitation (HP:0000713)1.78924075
129Fair hair (HP:0002286)1.78560800
130Incomplete penetrance (HP:0003829)1.78537679
131Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.77971863
132Autism (HP:0000717)1.77295402
133Midline defect of the nose (HP:0004122)1.76456865
134Pancreatic cysts (HP:0001737)1.76369265
135Tracheomalacia (HP:0002779)1.76283147
136Status epilepticus (HP:0002133)1.76172937
137Gait ataxia (HP:0002066)1.74872681
138Postaxial hand polydactyly (HP:0001162)1.74142088
139High anterior hairline (HP:0009890)1.73338149
140Abnormality of the labia minora (HP:0012880)1.72960569
141Aplasia/Hypoplasia of the tibia (HP:0005772)1.72504633
142Widely spaced teeth (HP:0000687)1.72034772
143Morphological abnormality of the middle ear (HP:0008609)1.71704838
144Ankyloglossia (HP:0010296)1.71146102
145Labial hypoplasia (HP:0000066)1.69897732
146Coronal craniosynostosis (HP:0004440)1.68501299
147Obsessive-compulsive behavior (HP:0000722)1.67948108
148Oligodactyly (hands) (HP:0001180)1.67512021
149Thickened helices (HP:0000391)1.67312998
150Neuroendocrine neoplasm (HP:0100634)1.66978390
151Cutaneous finger syndactyly (HP:0010554)1.66762959
152Clumsiness (HP:0002312)1.66740343
153Oligodactyly (HP:0012165)1.66460209
154Abnormal EKG (HP:0003115)1.66232270
155Abnormality of midbrain morphology (HP:0002418)1.66204177
156Molar tooth sign on MRI (HP:0002419)1.66204177
157Abnormality of the diencephalon (HP:0010662)1.65535305
158Lower limb amyotrophy (HP:0007210)1.64964600
159Cortical dysplasia (HP:0002539)1.63751093
160Hypoplastic labia majora (HP:0000059)1.63516329
161Gastroesophageal reflux (HP:0002020)1.63476141
162Preaxial hand polydactyly (HP:0001177)1.63262917
163Partial duplication of thumb phalanx (HP:0009944)1.62750699
164Pachygyria (HP:0001302)1.60924499

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.63545656
2NTRK34.34742743
3MARK13.86038845
4MAP3K93.27759187
5NTRK23.05003363
6MAP3K42.91140607
7CASK2.69412654
8MINK12.66157008
9KSR12.39538133
10NTRK12.33042546
11MAP2K72.30318731
12DAPK22.20351873
13FRK1.95146905
14PAK61.83164454
15MKNK21.80093533
16TNIK1.73993618
17RIPK41.71653191
18CAMKK11.63733309
19MAPK131.63101368
20SIK21.61348885
21MAP2K41.59231424
22SIK31.55344561
23PRKD31.51279861
24DAPK11.49342675
25CDK51.48452393
26KSR21.47258478
27DYRK21.43066166
28EPHA31.40152493
29MAPK151.31373487
30BMPR1B1.25393616
31PLK21.25164000
32SGK21.24047725
33LATS11.24029384
34MAP3K121.22554677
35SGK2231.19203361
36SGK4941.19203361
37CAMKK21.16976001
38PRPF4B1.12879859
39MKNK11.12686929
40PRKCG1.12160231
41PINK11.12127516
42WEE11.10043929
43PNCK1.09741333
44CSNK1G11.08974113
45CAMK1G1.02770670
46BCR1.02367812
47STK381.00011380
48PHKG20.99855331
49PHKG10.99855331
50CAMK2A0.99412979
51CDK180.95487133
52UHMK10.93951836
53ZAK0.93706985
54SGK30.93600388
55FES0.92589396
56TYRO30.91601972
57NUAK10.89849388
58BRD40.89200179
59TAOK10.88957122
60CDK190.88879679
61CDK150.86651942
62CSNK1A1L0.86428679
63SGK10.84244324
64CSNK1G30.83548711
65GRK50.82282096
66INSRR0.81057524
67CDK140.80986864
68MAP4K20.80849572
69CAMK2B0.79151348
70TSSK60.78687638
71STK110.78158189
72CCNB10.76919525
73FGFR20.76295303
74MAP3K20.74565127
75WNK30.73684628
76CAMK10.72887678
77MAP3K100.72801392
78STK38L0.72643459
79CDK11A0.72607949
80CSNK1G20.72341220
81LATS20.72237074
82STK390.71227057
83VRK10.70752449
84AKT30.70050371
85MAP3K60.68781056
86CDC70.67761316
87DYRK1A0.66994203
88RET0.65993090
89PAK30.65160618
90GRK70.64517988
91ACVR1B0.64163580
92CDK30.63303287
93LMTK20.63067047
94MARK20.61291142
95FGFR10.59215194
96RPS6KA30.59040437
97PRKCZ0.57731755
98ERBB30.57459281
99EPHB20.55951480
100PRKCH0.55340502
101PLK40.53873753
102CAMK40.52759749
103MAPK100.51627930
104FYN0.49770683
105TGFBR10.49544728
106BMPR20.49212356
107PTK2B0.48739298
108MAP3K130.48659888
109DYRK30.47816358
110CDC42BPA0.47170904
111CSNK1D0.47122091
112OXSR10.47091272
113TAF10.45518951
114CAMK1D0.45044827
115PRKCE0.44608550
116RAF10.44055864
117ADRBK10.42686342
118ERBB20.42447128
119DMPK0.40877400
120PKN10.40192293
121WNK10.40118362
122PRKACB0.39122481
123FGR0.39092226
124PDK10.38696931
125PRKCB0.38450377
126CSNK1E0.38228722
127PLK30.38074337
128NEK60.37442337
129ATM0.36466996
130FER0.36412995
131PRKDC0.36286624
132ROCK10.35934715
133RPS6KA20.35329831
134ADRBK20.34849075
135PDPK10.34589377
136CAMK2D0.33853873
137WNK40.33499312
138ICK0.33373962
139PRKG10.32936895
140NEK10.32927625
141GSK3B0.32266560
142MAPK80.31719446
143GRK10.31179343

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.85975096
2Synaptic vesicle cycle_Homo sapiens_hsa047212.77998981
3Circadian entrainment_Homo sapiens_hsa047132.69529066
4Olfactory transduction_Homo sapiens_hsa047402.64378539
5GABAergic synapse_Homo sapiens_hsa047272.59096110
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.57080389
7Morphine addiction_Homo sapiens_hsa050322.55399191
8Glutamatergic synapse_Homo sapiens_hsa047242.53918998
9Long-term potentiation_Homo sapiens_hsa047202.50227802
10Amphetamine addiction_Homo sapiens_hsa050312.38643327
11Salivary secretion_Homo sapiens_hsa049702.16249901
12Dopaminergic synapse_Homo sapiens_hsa047282.14933479
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.96333339
14Cholinergic synapse_Homo sapiens_hsa047251.95185343
15Insulin secretion_Homo sapiens_hsa049111.95011037
16Renin secretion_Homo sapiens_hsa049241.84226799
17Cocaine addiction_Homo sapiens_hsa050301.84059032
18Aldosterone synthesis and secretion_Homo sapiens_hsa049251.75955567
19Taste transduction_Homo sapiens_hsa047421.71357900
20Gastric acid secretion_Homo sapiens_hsa049711.70762216
21Serotonergic synapse_Homo sapiens_hsa047261.66682169
22Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.65818655
23Oxytocin signaling pathway_Homo sapiens_hsa049211.63478661
24Calcium signaling pathway_Homo sapiens_hsa040201.60477441
25Long-term depression_Homo sapiens_hsa047301.58280010
26Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.53523068
27Axon guidance_Homo sapiens_hsa043601.47063445
28Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.43805627
29Gap junction_Homo sapiens_hsa045401.43016562
30Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.39459978
31Phototransduction_Homo sapiens_hsa047441.37451497
32cAMP signaling pathway_Homo sapiens_hsa040241.32541287
33GnRH signaling pathway_Homo sapiens_hsa049121.30509328
34Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.28059673
35Glioma_Homo sapiens_hsa052141.26094653
36Type II diabetes mellitus_Homo sapiens_hsa049301.22819993
37Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.22584664
38Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.21209804
39Estrogen signaling pathway_Homo sapiens_hsa049151.19999475
40ErbB signaling pathway_Homo sapiens_hsa040121.15141707
41Melanogenesis_Homo sapiens_hsa049161.13506817
42Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.12329787
43cGMP-PKG signaling pathway_Homo sapiens_hsa040221.11580968
44Phosphatidylinositol signaling system_Homo sapiens_hsa040701.08030043
45TGF-beta signaling pathway_Homo sapiens_hsa043500.95966283
46Tight junction_Homo sapiens_hsa045300.94089034
47Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.93206146
48Dilated cardiomyopathy_Homo sapiens_hsa054140.92580290
49Collecting duct acid secretion_Homo sapiens_hsa049660.92414644
50Fanconi anemia pathway_Homo sapiens_hsa034600.92234897
51Butanoate metabolism_Homo sapiens_hsa006500.91381336
52Vascular smooth muscle contraction_Homo sapiens_hsa042700.90948229
53Oocyte meiosis_Homo sapiens_hsa041140.90532414
54Alcoholism_Homo sapiens_hsa050340.89758550
55Phospholipase D signaling pathway_Homo sapiens_hsa040720.87659856
56Dorso-ventral axis formation_Homo sapiens_hsa043200.87264285
57Pancreatic secretion_Homo sapiens_hsa049720.82342676
58Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.80789272
59Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.78611261
60Thyroid hormone synthesis_Homo sapiens_hsa049180.77459584
61Steroid biosynthesis_Homo sapiens_hsa001000.77001509
62Non-homologous end-joining_Homo sapiens_hsa034500.76159004
63MAPK signaling pathway_Homo sapiens_hsa040100.75948497
64Lysine degradation_Homo sapiens_hsa003100.75746563
65Choline metabolism in cancer_Homo sapiens_hsa052310.74856220
66Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.73115286
67Cardiac muscle contraction_Homo sapiens_hsa042600.73021592
68Thyroid hormone signaling pathway_Homo sapiens_hsa049190.71938661
69Neurotrophin signaling pathway_Homo sapiens_hsa047220.71476784
70Endometrial cancer_Homo sapiens_hsa052130.69410064
71Adherens junction_Homo sapiens_hsa045200.68879963
72Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.68750022
73Rap1 signaling pathway_Homo sapiens_hsa040150.67642472
74MicroRNAs in cancer_Homo sapiens_hsa052060.67360983
75mTOR signaling pathway_Homo sapiens_hsa041500.66280418
76Ras signaling pathway_Homo sapiens_hsa040140.64869675
77Wnt signaling pathway_Homo sapiens_hsa043100.64656221
78Systemic lupus erythematosus_Homo sapiens_hsa053220.64061977
79Nitrogen metabolism_Homo sapiens_hsa009100.62141400
80Circadian rhythm_Homo sapiens_hsa047100.61206339
81Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.60855604
82Carbohydrate digestion and absorption_Homo sapiens_hsa049730.60626544
83Vibrio cholerae infection_Homo sapiens_hsa051100.59840256
84Non-small cell lung cancer_Homo sapiens_hsa052230.59811221
85Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.59707800
86Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.59537919
87Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.59534759
88Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.58868540
89Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.58656669
90Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.55670451
91Basal transcription factors_Homo sapiens_hsa030220.55513948
92Colorectal cancer_Homo sapiens_hsa052100.55295426
93Glucagon signaling pathway_Homo sapiens_hsa049220.54977987
94Longevity regulating pathway - mammal_Homo sapiens_hsa042110.54937515
95Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.54443265
96Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.53253801
97Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.52506448
98Renal cell carcinoma_Homo sapiens_hsa052110.52467313
99Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.51464866
100Fatty acid biosynthesis_Homo sapiens_hsa000610.50663209
101Hedgehog signaling pathway_Homo sapiens_hsa043400.50403977
102VEGF signaling pathway_Homo sapiens_hsa043700.50400065
103Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.49503837
104Inositol phosphate metabolism_Homo sapiens_hsa005620.48787674
105Sphingolipid signaling pathway_Homo sapiens_hsa040710.48009981
106Pathways in cancer_Homo sapiens_hsa052000.47000543
107Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.46345837
108Propanoate metabolism_Homo sapiens_hsa006400.46021018
109Prolactin signaling pathway_Homo sapiens_hsa049170.45192484
110Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.45009151
111Maturity onset diabetes of the young_Homo sapiens_hsa049500.44249019
112Insulin signaling pathway_Homo sapiens_hsa049100.43940022
113Endocytosis_Homo sapiens_hsa041440.40421372
114Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.40067700
115Bile secretion_Homo sapiens_hsa049760.37870670
116Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.37256972
117Ovarian steroidogenesis_Homo sapiens_hsa049130.36311836
118Chemokine signaling pathway_Homo sapiens_hsa040620.35938478
119Hippo signaling pathway_Homo sapiens_hsa043900.35240460
120Basal cell carcinoma_Homo sapiens_hsa052170.34376871
121Prion diseases_Homo sapiens_hsa050200.34271191
122Melanoma_Homo sapiens_hsa052180.32673065
123African trypanosomiasis_Homo sapiens_hsa051430.30484091
124Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.29462047
125Type I diabetes mellitus_Homo sapiens_hsa049400.26618323

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