Rank | Gene Set | Z-score |
---|---|---|
1 | fusion of sperm to egg plasma membrane (GO:0007342) | 5.08448901 |
2 | nuclear pore complex assembly (GO:0051292) | 4.87927028 |
3 | regulation of RNA export from nucleus (GO:0046831) | 4.77051248 |
4 | nuclear pore organization (GO:0006999) | 4.61133473 |
5 | multicellular organism reproduction (GO:0032504) | 4.53419942 |
6 | cilium or flagellum-dependent cell motility (GO:0001539) | 4.45480692 |
7 | sperm-egg recognition (GO:0035036) | 4.41605895 |
8 | piRNA metabolic process (GO:0034587) | 4.29431408 |
9 | binding of sperm to zona pellucida (GO:0007339) | 4.28052392 |
10 | pre-miRNA processing (GO:0031054) | 4.13623342 |
11 | cell wall macromolecule catabolic process (GO:0016998) | 4.08671805 |
12 | cell wall macromolecule metabolic process (GO:0044036) | 4.08671805 |
13 | regulation of DNA methylation (GO:0044030) | 3.98236272 |
14 | negative regulation of fibroblast apoptotic process (GO:2000270) | 3.93789687 |
15 | regulation of nucleobase-containing compound transport (GO:0032239) | 3.89036443 |
16 | pore complex assembly (GO:0046931) | 3.85745195 |
17 | protein localization to chromosome, centromeric region (GO:0071459) | 3.85594063 |
18 | negative regulation of histone methylation (GO:0031061) | 3.85360132 |
19 | cell-cell recognition (GO:0009988) | 3.84620681 |
20 | mitotic sister chromatid cohesion (GO:0007064) | 3.81936444 |
21 | cytoplasmic mRNA processing body assembly (GO:0033962) | 3.79550987 |
22 | reproduction (GO:0000003) | 3.70845900 |
23 | microtubule depolymerization (GO:0007019) | 3.69231107 |
24 | protein localization to kinetochore (GO:0034501) | 3.66671628 |
25 | plasma membrane fusion (GO:0045026) | 3.51716226 |
26 | acrosome assembly (GO:0001675) | 3.51195472 |
27 | mitotic metaphase plate congression (GO:0007080) | 3.39391873 |
28 | mitotic nuclear envelope disassembly (GO:0007077) | 3.38376300 |
29 | regulation of centriole replication (GO:0046599) | 3.37537256 |
30 | protoporphyrinogen IX metabolic process (GO:0046501) | 3.35214666 |
31 | axonemal dynein complex assembly (GO:0070286) | 3.34140166 |
32 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.32567240 |
33 | male meiosis (GO:0007140) | 3.31393426 |
34 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.30723876 |
35 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.30723876 |
36 | artery development (GO:0060840) | 3.30445253 |
37 | anterior/posterior axis specification, embryo (GO:0008595) | 3.28587691 |
38 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 3.24978531 |
39 | notochord development (GO:0030903) | 3.22759655 |
40 | motile cilium assembly (GO:0044458) | 3.22694932 |
41 | mitotic chromosome condensation (GO:0007076) | 3.21998021 |
42 | protoporphyrinogen IX biosynthetic process (GO:0006782) | 3.20067331 |
43 | cellular protein complex localization (GO:0034629) | 3.19181129 |
44 | sperm motility (GO:0030317) | 3.18733916 |
45 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.16518844 |
46 | membrane disassembly (GO:0030397) | 3.15322280 |
47 | nuclear envelope disassembly (GO:0051081) | 3.15322280 |
48 | kinetochore organization (GO:0051383) | 3.12756185 |
49 | erythrocyte development (GO:0048821) | 3.11293123 |
50 | metaphase plate congression (GO:0051310) | 3.10526263 |
51 | chromosome condensation (GO:0030261) | 3.10457297 |
52 | synaptonemal complex assembly (GO:0007130) | 3.09114201 |
53 | regulation of meiosis I (GO:0060631) | 3.07974826 |
54 | chondrocyte proliferation (GO:0035988) | 3.07058959 |
55 | sister chromatid segregation (GO:0000819) | 3.06641405 |
56 | paraxial mesoderm development (GO:0048339) | 3.04308322 |
57 | synaptonemal complex organization (GO:0070193) | 3.04014734 |
58 | regulation of chromatin binding (GO:0035561) | 3.03774898 |
59 | mitotic sister chromatid segregation (GO:0000070) | 3.01718872 |
60 | regulation of centrosome cycle (GO:0046605) | 3.00040336 |
61 | regulation of fibroblast apoptotic process (GO:2000269) | 2.97558754 |
62 | meiotic cell cycle (GO:0051321) | 2.97253016 |
63 | DNA packaging (GO:0006323) | 2.95982212 |
64 | outer ear morphogenesis (GO:0042473) | 2.95395430 |
65 | NLS-bearing protein import into nucleus (GO:0006607) | 2.94414585 |
66 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 2.93554282 |
67 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 2.93554282 |
68 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 2.93554282 |
69 | spermatid development (GO:0007286) | 2.91897511 |
70 | gene silencing by RNA (GO:0031047) | 2.90976129 |
71 | regulation of chromosome segregation (GO:0051983) | 2.90948209 |
72 | regulation of spindle organization (GO:0090224) | 2.90540953 |
73 | mRNA stabilization (GO:0048255) | 2.88108495 |
74 | RNA stabilization (GO:0043489) | 2.88108495 |
75 | regulation of cAMP-dependent protein kinase activity (GO:2000479) | 2.86778109 |
76 | meiotic chromosome segregation (GO:0045132) | 2.86486114 |
77 | nerve growth factor signaling pathway (GO:0038180) | 2.85549307 |
78 | establishment of chromosome localization (GO:0051303) | 2.84612202 |
79 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.84577842 |
80 | negative regulation of chromosome segregation (GO:0051985) | 2.80885130 |
81 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.80853932 |
82 | negative regulation of DNA repair (GO:0045738) | 2.80498019 |
83 | embryonic process involved in female pregnancy (GO:0060136) | 2.79859055 |
84 | spindle checkpoint (GO:0031577) | 2.79840802 |
85 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 2.79292974 |
86 | axon extension involved in axon guidance (GO:0048846) | 2.79292974 |
87 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.78999735 |
88 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.78999735 |
89 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.78999735 |
90 | negative regulation of sister chromatid segregation (GO:0033046) | 2.78999735 |
91 | regulation of histone H3-K9 methylation (GO:0051570) | 2.78591898 |
92 | regulation of NFAT protein import into nucleus (GO:0051532) | 2.78375810 |
93 | DNA methylation involved in gamete generation (GO:0043046) | 2.77658777 |
94 | cell migration involved in heart development (GO:0060973) | 2.77574769 |
95 | histone exchange (GO:0043486) | 2.76738243 |
96 | N-terminal protein amino acid acetylation (GO:0006474) | 2.76447549 |
97 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.74344620 |
98 | iron ion import (GO:0097286) | 2.71330610 |
99 | DNA replication checkpoint (GO:0000076) | 2.70542598 |
100 | protein complex localization (GO:0031503) | 2.69438665 |
101 | endocardial cushion morphogenesis (GO:0003203) | 2.68254478 |
102 | meiotic nuclear division (GO:0007126) | 2.67718181 |
103 | spindle assembly checkpoint (GO:0071173) | 2.66786645 |
104 | regulation of mitotic sister chromatid separation (GO:0010965) | 2.66584685 |
105 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.66584685 |
106 | regulation of sister chromatid segregation (GO:0033045) | 2.66584685 |
107 | Notch signaling involved in heart development (GO:0061314) | 2.63673385 |
108 | acrosome reaction (GO:0007340) | 2.62044762 |
109 | oxygen transport (GO:0015671) | 2.61575990 |
110 | regulation of chromatin silencing (GO:0031935) | 2.61570552 |
111 | cell migration involved in sprouting angiogenesis (GO:0002042) | 2.60595993 |
112 | regulation of centrosome duplication (GO:0010824) | 2.60471183 |
113 | mitotic spindle assembly checkpoint (GO:0007094) | 2.60328393 |
114 | kinetochore assembly (GO:0051382) | 2.59078045 |
115 | mitotic spindle checkpoint (GO:0071174) | 2.58936417 |
116 | epithelial cilium movement (GO:0003351) | 2.58798727 |
117 | regulation of mitotic spindle organization (GO:0060236) | 2.58703556 |
118 | protein K6-linked ubiquitination (GO:0085020) | 2.58629363 |
119 | facial nerve structural organization (GO:0021612) | 2.58357577 |
120 | chromosome organization involved in meiosis (GO:0070192) | 2.58059268 |
121 | nodal signaling pathway (GO:0038092) | 2.57384432 |
122 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.56809901 |
123 | single fertilization (GO:0007338) | 2.56411289 |
124 | positive regulation of chromosome segregation (GO:0051984) | 2.55475968 |
125 | DNA replication initiation (GO:0006270) | 2.54362039 |
126 | glycine transport (GO:0015816) | 2.53329494 |
127 | protein localization to chromosome (GO:0034502) | 2.52256623 |
128 | musculoskeletal movement (GO:0050881) | 2.52112153 |
129 | multicellular organismal movement (GO:0050879) | 2.52112153 |
130 | mitotic G2/M transition checkpoint (GO:0044818) | 2.51567151 |
131 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 2.50935387 |
132 | chromatin remodeling at centromere (GO:0031055) | 2.50581062 |
133 | heart valve formation (GO:0003188) | 2.49215549 |
134 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.47679504 |
135 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.47679504 |
136 | regulation of sister chromatid cohesion (GO:0007063) | 2.47553567 |
137 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 2.46391959 |
138 | DNA unwinding involved in DNA replication (GO:0006268) | 2.44060120 |
139 | porphyrin-containing compound biosynthetic process (GO:0006779) | 2.43375681 |
140 | negative regulation of meiosis (GO:0045835) | 2.43284572 |
141 | histone H2B ubiquitination (GO:0033523) | 2.42167817 |
142 | histone monoubiquitination (GO:0010390) | 2.41686965 |
143 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787) | 2.41457930 |
144 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 2.39959082 |
145 | interkinetic nuclear migration (GO:0022027) | 2.39476741 |
146 | cytoskeleton-dependent cytokinesis (GO:0061640) | 2.36375167 |
147 | histone ubiquitination (GO:0016574) | 2.36162341 |
148 | morphogenesis of an epithelial sheet (GO:0002011) | 2.34975861 |
149 | heparan sulfate proteoglycan biosynthetic process (GO:0015012) | 2.34066583 |
150 | regulation of DNA damage checkpoint (GO:2000001) | 2.32896199 |
151 | hemoglobin metabolic process (GO:0020027) | 2.32585508 |
152 | negative regulation of neurotransmitter secretion (GO:0046929) | 2.32458559 |
153 | dorsal/ventral axis specification (GO:0009950) | 2.32022624 |
154 | peptidyl-threonine phosphorylation (GO:0018107) | 2.31855320 |
155 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 2.30605216 |
156 | anatomical structure arrangement (GO:0048532) | 2.29438039 |
157 | spermatid nucleus differentiation (GO:0007289) | 2.28986124 |
158 | embryonic camera-type eye morphogenesis (GO:0048596) | 2.28754501 |
159 | hippo signaling (GO:0035329) | 2.28496176 |
160 | peptidyl-threonine modification (GO:0018210) | 2.28394117 |
161 | mitotic cytokinesis (GO:0000281) | 2.27074509 |
162 | gas transport (GO:0015669) | 2.26150733 |
163 | erythrocyte maturation (GO:0043249) | 2.26135743 |
164 | snRNA transcription (GO:0009301) | 2.26021600 |
165 | regulation of gene silencing by miRNA (GO:0060964) | 2.25465786 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 9.17221892 |
2 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 6.34589124 |
3 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 6.08311906 |
4 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.76995540 |
5 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.69438415 |
6 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.96921109 |
7 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.96762686 |
8 | GATA1_22025678_ChIP-Seq_K562_Human | 2.95533681 |
9 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.91574901 |
10 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 2.79623836 |
11 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.50909970 |
12 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.50850273 |
13 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.22009931 |
14 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.13426375 |
15 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.12769237 |
16 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.09852452 |
17 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 2.07811405 |
18 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.96167173 |
19 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.83749193 |
20 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.83060638 |
21 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.82272772 |
22 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.80664607 |
23 | * NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.78518309 |
24 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.74973032 |
25 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.74074536 |
26 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.69218604 |
27 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.58904699 |
28 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.58764393 |
29 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.56586381 |
30 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.56511770 |
31 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.55501141 |
32 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.55251859 |
33 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.55185932 |
34 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.54198015 |
35 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.51849793 |
36 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.50687852 |
37 | EWS_26573619_Chip-Seq_HEK293_Human | 1.50072346 |
38 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.48171230 |
39 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.47881140 |
40 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.47444968 |
41 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.46011955 |
42 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.44097715 |
43 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.43605467 |
44 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.42904625 |
45 | TP53_16413492_ChIP-PET_HCT116_Human | 1.42319177 |
46 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.42196426 |
47 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.40296251 |
48 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.39832320 |
49 | P300_19829295_ChIP-Seq_ESCs_Human | 1.39328029 |
50 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.38862908 |
51 | FUS_26573619_Chip-Seq_HEK293_Human | 1.36027416 |
52 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.34877756 |
53 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 1.33755971 |
54 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.31885609 |
55 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.29853228 |
56 | GATA1_19941826_ChIP-Seq_K562_Human | 1.25762373 |
57 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.25259771 |
58 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.23949151 |
59 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.23855844 |
60 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.23855844 |
61 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.21968897 |
62 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.21356414 |
63 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.20643990 |
64 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.20448442 |
65 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.19266897 |
66 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.17928858 |
67 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.17297908 |
68 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.14252266 |
69 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.14151230 |
70 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.14088101 |
71 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.13613094 |
72 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 1.12867478 |
73 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.12167196 |
74 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 1.11695959 |
75 | * EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.11077792 |
76 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.10853698 |
77 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.10618828 |
78 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.10604883 |
79 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.10258397 |
80 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.09842931 |
81 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.09398140 |
82 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.09180861 |
83 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.08469953 |
84 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.07938755 |
85 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.07654472 |
86 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.07634304 |
87 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.07483514 |
88 | GF1B_26923725_Chip-Seq_HPCs_Mouse | 1.06628769 |
89 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.06378802 |
90 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.04961904 |
91 | * TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.04403355 |
92 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.03543217 |
93 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.03344837 |
94 | * ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.03113492 |
95 | STAT3_23295773_ChIP-Seq_U87_Human | 1.02477825 |
96 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.01698290 |
97 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.01182142 |
98 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.00565155 |
99 | * SOX9_26525672_Chip-Seq_HEART_Mouse | 0.98702376 |
100 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.98686531 |
101 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.98023015 |
102 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.98023015 |
103 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.98023015 |
104 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.96687168 |
105 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 0.96567417 |
106 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.95895777 |
107 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.94886862 |
108 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 0.94837759 |
109 | POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 0.94409097 |
110 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.94110822 |
111 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.93589310 |
112 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.93572593 |
113 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.92825527 |
114 | CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.91742239 |
115 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.91718900 |
116 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.91523293 |
117 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.91394361 |
118 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 0.91092827 |
119 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.90924053 |
120 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.89433657 |
121 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.88255610 |
122 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.88255610 |
123 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.87551134 |
124 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.87465733 |
125 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.87441225 |
126 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.87256326 |
127 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 0.86415504 |
128 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.85127990 |
129 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.84451369 |
130 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.83549835 |
131 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.83073948 |
132 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.82888480 |
133 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.82154384 |
134 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 0.82004049 |
135 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 0.80703623 |
136 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 0.79364702 |
137 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.78334208 |
138 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.78201295 |
139 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.78063963 |
140 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.77662662 |
141 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.77104137 |
142 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.76798680 |
143 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.75101511 |
144 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.75003360 |
145 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.74276458 |
146 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 0.73920858 |
147 | * RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 0.73731030 |
148 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.73300639 |
149 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.73161123 |
150 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.72205463 |
151 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.70701227 |
152 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.70040015 |
153 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.69544468 |
154 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 0.67655252 |
155 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.67178968 |
156 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.67019478 |
157 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 0.66873892 |
158 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.66820933 |
159 | CJUN_26792858_Chip-Seq_BT549_Human | 0.65873777 |
160 | * BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.65575107 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005451_abnormal_body_composition | 3.14593812 |
2 | MP0005410_abnormal_fertilization | 3.07797357 |
3 | MP0000566_synostosis | 2.95201353 |
4 | MP0010094_abnormal_chromosome_stability | 2.83021187 |
5 | MP0008057_abnormal_DNA_replication | 2.81937694 |
6 | MP0003111_abnormal_nucleus_morphology | 2.77154961 |
7 | MP0004147_increased_porphyrin_level | 2.74128413 |
8 | MP0010030_abnormal_orbit_morphology | 2.71446242 |
9 | MP0003693_abnormal_embryo_hatching | 2.65836873 |
10 | MP0003077_abnormal_cell_cycle | 2.45153802 |
11 | MP0008438_abnormal_cutaneous_collagen | 2.31768480 |
12 | MP0003221_abnormal_cardiomyocyte_apopto | 2.26330947 |
13 | MP0008877_abnormal_DNA_methylation | 2.12158473 |
14 | MP0005257_abnormal_intraocular_pressure | 2.07009403 |
15 | MP0002877_abnormal_melanocyte_morpholog | 2.05970115 |
16 | MP0003705_abnormal_hypodermis_morpholog | 2.03568376 |
17 | MP0010352_gastrointestinal_tract_polyps | 2.01868977 |
18 | MP0008007_abnormal_cellular_replicative | 1.97501903 |
19 | MP0008058_abnormal_DNA_repair | 1.91322853 |
20 | MP0004957_abnormal_blastocyst_morpholog | 1.83175509 |
21 | MP0010307_abnormal_tumor_latency | 1.81565560 |
22 | MP0001929_abnormal_gametogenesis | 1.80310746 |
23 | MP0009053_abnormal_anal_canal | 1.69179506 |
24 | MP0003950_abnormal_plasma_membrane | 1.65441708 |
25 | MP0005076_abnormal_cell_differentiation | 1.65024391 |
26 | MP0002282_abnormal_trachea_morphology | 1.64874776 |
27 | MP0003123_paternal_imprinting | 1.58891481 |
28 | MP0002210_abnormal_sex_determination | 1.58367807 |
29 | MP0008932_abnormal_embryonic_tissue | 1.58111162 |
30 | MP0009697_abnormal_copulation | 1.56655780 |
31 | MP0003941_abnormal_skin_development | 1.56138298 |
32 | MP0001299_abnormal_eye_distance/ | 1.53289924 |
33 | MP0005187_abnormal_penis_morphology | 1.51871175 |
34 | MP0005503_abnormal_tendon_morphology | 1.51255336 |
35 | MP0003566_abnormal_cell_adhesion | 1.49369647 |
36 | MP0001672_abnormal_embryogenesis/_devel | 1.47754026 |
37 | MP0005380_embryogenesis_phenotype | 1.47754026 |
38 | MP0001730_embryonic_growth_arrest | 1.46549595 |
39 | MP0000350_abnormal_cell_proliferation | 1.44252307 |
40 | MP0003984_embryonic_growth_retardation | 1.43135319 |
41 | MP0001293_anophthalmia | 1.41242160 |
42 | MP0002088_abnormal_embryonic_growth/wei | 1.40663473 |
43 | MP0002697_abnormal_eye_size | 1.38851596 |
44 | MP0004233_abnormal_muscle_weight | 1.37069641 |
45 | MP0005083_abnormal_biliary_tract | 1.34476714 |
46 | MP0003698_abnormal_male_reproductive | 1.32314547 |
47 | MP0010368_abnormal_lymphatic_system | 1.30185653 |
48 | MP0009703_decreased_birth_body | 1.29911824 |
49 | MP0003091_abnormal_cell_migration | 1.29091998 |
50 | MP0005023_abnormal_wound_healing | 1.27110292 |
51 | MP0001697_abnormal_embryo_size | 1.25911419 |
52 | MP0005275_abnormal_skin_tensile | 1.25896673 |
53 | MP0003937_abnormal_limbs/digits/tail_de | 1.25078928 |
54 | MP0001145_abnormal_male_reproductive | 1.24605940 |
55 | MP0004185_abnormal_adipocyte_glucose | 1.24089012 |
56 | MP0000569_abnormal_digit_pigmentation | 1.22570355 |
57 | MP0002086_abnormal_extraembryonic_tissu | 1.21679025 |
58 | MP0003890_abnormal_embryonic-extraembry | 1.19283387 |
59 | MP0002084_abnormal_developmental_patter | 1.18688821 |
60 | MP0009672_abnormal_birth_weight | 1.18056928 |
61 | MP0004197_abnormal_fetal_growth/weight/ | 1.17260774 |
62 | MP0005508_abnormal_skeleton_morphology | 1.17130868 |
63 | MP0002085_abnormal_embryonic_tissue | 1.16624850 |
64 | MP0003115_abnormal_respiratory_system | 1.15444653 |
65 | MP0000653_abnormal_sex_gland | 1.15210406 |
66 | MP0004145_abnormal_muscle_electrophysio | 1.13333587 |
67 | MP0000749_muscle_degeneration | 1.11929630 |
68 | MP0001119_abnormal_female_reproductive | 1.08277072 |
69 | MP0003656_abnormal_erythrocyte_physiolo | 1.07533587 |
70 | MP0000733_abnormal_muscle_development | 1.07413551 |
71 | MP0006054_spinal_hemorrhage | 1.06687899 |
72 | MP0000751_myopathy | 1.06366981 |
73 | MP0003121_genomic_imprinting | 1.04334058 |
74 | MP0004808_abnormal_hematopoietic_stem | 1.03267804 |
75 | MP0000049_abnormal_middle_ear | 1.02814675 |
76 | MP0010630_abnormal_cardiac_muscle | 1.01871645 |
77 | MP0000432_abnormal_head_morphology | 0.99765267 |
78 | MP0004084_abnormal_cardiac_muscle | 0.99597026 |
79 | MP0004087_abnormal_muscle_fiber | 0.99358181 |
80 | MP0003279_aneurysm | 0.99337134 |
81 | MP0003755_abnormal_palate_morphology | 0.98756363 |
82 | MP0002177_abnormal_outer_ear | 0.97725963 |
83 | MP0003385_abnormal_body_wall | 0.97476072 |
84 | MP0002092_abnormal_eye_morphology | 0.97368764 |
85 | MP0002249_abnormal_larynx_morphology | 0.97342222 |
86 | MP0002233_abnormal_nose_morphology | 0.96700744 |
87 | MP0000490_abnormal_crypts_of | 0.96575849 |
88 | MP0000747_muscle_weakness | 0.94823900 |
89 | MP0010234_abnormal_vibrissa_follicle | 0.94795234 |
90 | MP0003718_maternal_effect | 0.94623213 |
91 | MP0003828_pulmonary_edema | 0.94521115 |
92 | MP0004272_abnormal_basement_membrane | 0.93882800 |
93 | MP0000428_abnormal_craniofacial_morphol | 0.92389785 |
94 | MP0008789_abnormal_olfactory_epithelium | 0.92244892 |
95 | MP0002161_abnormal_fertility/fecundity | 0.92060199 |
96 | MP0004215_abnormal_myocardial_fiber | 0.89688664 |
97 | MP0002080_prenatal_lethality | 0.89374650 |
98 | MP0002269_muscular_atrophy | 0.89189366 |
99 | MP0003861_abnormal_nervous_system | 0.88183944 |
100 | MP0002108_abnormal_muscle_morphology | 0.87667745 |
101 | MP0009250_abnormal_appendicular_skeleto | 0.86438317 |
102 | MP0000767_abnormal_smooth_muscle | 0.86384984 |
103 | MP0000537_abnormal_urethra_morphology | 0.86015760 |
104 | MP0003935_abnormal_craniofacial_develop | 0.85864166 |
105 | MP0005621_abnormal_cell_physiology | 0.85585207 |
106 | MP0005248_abnormal_Harderian_gland | 0.85364029 |
107 | MP0005620_abnormal_muscle_contractility | 0.85348241 |
108 | MP0002925_abnormal_cardiovascular_devel | 0.84916853 |
109 | MP0002932_abnormal_joint_morphology | 0.84746558 |
110 | MP0001958_emphysema | 0.83339247 |
111 | MP0001529_abnormal_vocalization | 0.82721350 |
112 | MP0002102_abnormal_ear_morphology | 0.81823459 |
113 | MP0000313_abnormal_cell_death | 0.80846261 |
114 | MP0005623_abnormal_meninges_morphology | 0.80651137 |
115 | MP0003448_altered_tumor_morphology | 0.80400414 |
116 | MP0004130_abnormal_muscle_cell | 0.80210425 |
117 | MP0003119_abnormal_digestive_system | 0.79011605 |
118 | MP0000266_abnormal_heart_morphology | 0.78776653 |
119 | MP0002972_abnormal_cardiac_muscle | 0.78678555 |
120 | MP0000759_abnormal_skeletal_muscle | 0.78368608 |
121 | MP0002653_abnormal_ependyma_morphology | 0.77843838 |
122 | MP0003453_abnormal_keratinocyte_physiol | 0.77587161 |
123 | MP0002089_abnormal_postnatal_growth/wei | 0.76180831 |
124 | MP0001286_abnormal_eye_development | 0.76079539 |
125 | MP0005389_reproductive_system_phenotype | 0.75567015 |
126 | MP0003567_abnormal_fetal_cardiomyocyte | 0.75543608 |
127 | MP0001175_abnormal_lung_morphology | 0.75420349 |
128 | MP0001915_intracranial_hemorrhage | 0.74261562 |
129 | MP0002109_abnormal_limb_morphology | 0.74168303 |
130 | MP0009384_cardiac_valve_regurgitation | 0.74003740 |
131 | MP0002009_preneoplasia | 0.73889423 |
132 | MP0002081_perinatal_lethality | 0.73375998 |
133 | MP0008770_decreased_survivor_rate | 0.73307254 |
134 | MP0005390_skeleton_phenotype | 0.72138699 |
135 | MP0002111_abnormal_tail_morphology | 0.71863006 |
136 | MP0000163_abnormal_cartilage_morphology | 0.71572892 |
137 | MP0002113_abnormal_skeleton_development | 0.71145690 |
138 | MP0002115_abnormal_skeleton_extremities | 0.69574627 |
139 | MP0004134_abnormal_chest_morphology | 0.69132157 |
140 | MP0000762_abnormal_tongue_morphology | 0.68966055 |
141 | MP0003942_abnormal_urinary_system | 0.68929272 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 4.39837184 |
2 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.30651642 |
3 | Absent/shortened dynein arms (HP:0200106) | 3.30651642 |
4 | Thyroid carcinoma (HP:0002890) | 3.08925461 |
5 | Neonatal short-limb short stature (HP:0008921) | 3.07908824 |
6 | Dysmetric saccades (HP:0000641) | 3.02366001 |
7 | Missing ribs (HP:0000921) | 2.96295144 |
8 | Osteomalacia (HP:0002749) | 2.93059844 |
9 | Chromsome breakage (HP:0040012) | 2.88247155 |
10 | Protrusio acetabuli (HP:0003179) | 2.82066592 |
11 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.79542330 |
12 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.71399560 |
13 | Short 4th metacarpal (HP:0010044) | 2.71399560 |
14 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.69325559 |
15 | Medulloblastoma (HP:0002885) | 2.62527293 |
16 | Neoplasm of the small intestine (HP:0100833) | 2.62443635 |
17 | Nemaline bodies (HP:0003798) | 2.61174954 |
18 | Impulsivity (HP:0100710) | 2.56687734 |
19 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 2.52852140 |
20 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 2.48757828 |
21 | Biliary tract neoplasm (HP:0100574) | 2.46788933 |
22 | Selective tooth agenesis (HP:0001592) | 2.42745745 |
23 | Rhinitis (HP:0012384) | 2.38814416 |
24 | Muscle fiber inclusion bodies (HP:0100299) | 2.38738930 |
25 | Chronic bronchitis (HP:0004469) | 2.33034790 |
26 | Premature rupture of membranes (HP:0001788) | 2.31057376 |
27 | Mesomelia (HP:0003027) | 2.28190832 |
28 | Heterotopia (HP:0002282) | 2.26072556 |
29 | Short middle phalanx of the 5th finger (HP:0004220) | 2.26070006 |
30 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.25342829 |
31 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.25342829 |
32 | Acute myeloid leukemia (HP:0004808) | 2.24777706 |
33 | Termporal pattern (HP:0011008) | 2.19982229 |
34 | Insidious onset (HP:0003587) | 2.19982229 |
35 | Bladder carcinoma (HP:0002862) | 2.18334823 |
36 | Bladder neoplasm (HP:0009725) | 2.18334823 |
37 | Ectopic kidney (HP:0000086) | 2.17490396 |
38 | Short nail (HP:0001799) | 2.17315033 |
39 | Hypochromic microcytic anemia (HP:0004840) | 2.14971350 |
40 | Curly hair (HP:0002212) | 2.12686042 |
41 | Skull defect (HP:0001362) | 2.12507000 |
42 | Meckel diverticulum (HP:0002245) | 2.12420232 |
43 | Subacute progressive viral hepatitis (HP:0006572) | 2.12415057 |
44 | Subaortic stenosis (HP:0001682) | 2.10656659 |
45 | Abnormality of the left ventricular outflow tract (HP:0011103) | 2.10656659 |
46 | Vertebral arch anomaly (HP:0008438) | 2.10319230 |
47 | Abnormal spermatogenesis (HP:0008669) | 2.09787500 |
48 | Abnormality of chromosome stability (HP:0003220) | 2.08776071 |
49 | Cubitus valgus (HP:0002967) | 2.08535743 |
50 | Cystic hygroma (HP:0000476) | 2.08485364 |
51 | Aortic aneurysm (HP:0004942) | 2.07637345 |
52 | Hepatoblastoma (HP:0002884) | 2.06720810 |
53 | Ankle contracture (HP:0006466) | 2.04918036 |
54 | Infertility (HP:0000789) | 2.04354428 |
55 | Rhizomelia (HP:0008905) | 2.03216824 |
56 | Limited elbow extension (HP:0001377) | 2.03088729 |
57 | Abnormality of the ileum (HP:0001549) | 2.02981917 |
58 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.02953322 |
59 | Adactyly (HP:0009776) | 2.01017402 |
60 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.00899543 |
61 | Papillary thyroid carcinoma (HP:0002895) | 1.98700328 |
62 | Supernumerary spleens (HP:0009799) | 1.94463071 |
63 | Neoplasm of the rectum (HP:0100743) | 1.94131793 |
64 | Overgrowth (HP:0001548) | 1.94097864 |
65 | Pheochromocytoma (HP:0002666) | 1.91472560 |
66 | Broad palm (HP:0001169) | 1.90693223 |
67 | Shoulder girdle muscle weakness (HP:0003547) | 1.90059521 |
68 | Fibular hypoplasia (HP:0003038) | 1.89723193 |
69 | Birth length less than 3rd percentile (HP:0003561) | 1.88823708 |
70 | Complete atrioventricular canal defect (HP:0001674) | 1.88487379 |
71 | Abnormality of the anterior horn cell (HP:0006802) | 1.88181104 |
72 | Degeneration of anterior horn cells (HP:0002398) | 1.88181104 |
73 | 11 pairs of ribs (HP:0000878) | 1.87837673 |
74 | Neoplasm of the oral cavity (HP:0100649) | 1.87402739 |
75 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.87331568 |
76 | Coronal craniosynostosis (HP:0004440) | 1.87071239 |
77 | Abnormal ciliary motility (HP:0012262) | 1.86830116 |
78 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.86346330 |
79 | Syringomyelia (HP:0003396) | 1.85931693 |
80 | Spinal cord lesions (HP:0100561) | 1.85931693 |
81 | Uterine leiomyosarcoma (HP:0002891) | 1.85646766 |
82 | Leiomyosarcoma (HP:0100243) | 1.85646766 |
83 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.85249219 |
84 | Absent epiphyses (HP:0010577) | 1.85249219 |
85 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.84413927 |
86 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.84413927 |
87 | Abnormality of the right ventricle (HP:0001707) | 1.84387945 |
88 | Acanthocytosis (HP:0001927) | 1.84125201 |
89 | Ankyloglossia (HP:0010296) | 1.84026229 |
90 | Pelvic girdle muscle weakness (HP:0003749) | 1.82978401 |
91 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.82885844 |
92 | Gastrointestinal carcinoma (HP:0002672) | 1.82885844 |
93 | Abnormality of the 4th metacarpal (HP:0010012) | 1.82447030 |
94 | Type 1 muscle fiber predominance (HP:0003803) | 1.82320852 |
95 | Increased nuchal translucency (HP:0010880) | 1.81863214 |
96 | Absent radius (HP:0003974) | 1.81861076 |
97 | Uterine neoplasm (HP:0010784) | 1.81355938 |
98 | Rimmed vacuoles (HP:0003805) | 1.81327337 |
99 | Neoplasm of the thyroid gland (HP:0100031) | 1.81315647 |
100 | Embryonal renal neoplasm (HP:0011794) | 1.80132650 |
101 | Duodenal stenosis (HP:0100867) | 1.79698501 |
102 | Small intestinal stenosis (HP:0012848) | 1.79698501 |
103 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.79401901 |
104 | Fair hair (HP:0002286) | 1.79325985 |
105 | Cupped ribs (HP:0000887) | 1.79092770 |
106 | High pitched voice (HP:0001620) | 1.78054742 |
107 | Aplasia/Hypoplasia of the scapulae (HP:0006713) | 1.76263548 |
108 | Hypoplastic scapulae (HP:0000882) | 1.76263548 |
109 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.74751959 |
110 | Male infertility (HP:0003251) | 1.73278980 |
111 | Insomnia (HP:0100785) | 1.71595777 |
112 | Abnormality of the septum pellucidum (HP:0007375) | 1.70960922 |
113 | Broad alveolar ridges (HP:0000187) | 1.70797020 |
114 | Wrist flexion contracture (HP:0001239) | 1.70564668 |
115 | Broad distal phalanx of finger (HP:0009836) | 1.70421445 |
116 | Aortic dissection (HP:0002647) | 1.70221870 |
117 | Poikilocytosis (HP:0004447) | 1.69602094 |
118 | Dislocated radial head (HP:0003083) | 1.69274808 |
119 | Microglossia (HP:0000171) | 1.69221640 |
120 | Spastic diplegia (HP:0001264) | 1.69195048 |
121 | Short ribs (HP:0000773) | 1.68538122 |
122 | Short humerus (HP:0005792) | 1.66693466 |
123 | Rhabdomyosarcoma (HP:0002859) | 1.65846749 |
124 | Abnormality of incisor morphology (HP:0011063) | 1.65563957 |
125 | Absent forearm bone (HP:0003953) | 1.65522019 |
126 | Aplasia involving forearm bones (HP:0009822) | 1.65522019 |
127 | Soft skin (HP:0000977) | 1.65162995 |
128 | Short middle phalanx of finger (HP:0005819) | 1.64761668 |
129 | Hypoplastic labia majora (HP:0000059) | 1.64693516 |
130 | Cervical subluxation (HP:0003308) | 1.64484141 |
131 | Obsessive-compulsive behavior (HP:0000722) | 1.63950816 |
132 | Long eyelashes (HP:0000527) | 1.63276470 |
133 | Sloping forehead (HP:0000340) | 1.62997046 |
134 | Synostosis of carpal bones (HP:0005048) | 1.62768870 |
135 | Deviation of the thumb (HP:0009603) | 1.62619919 |
136 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 1.62359960 |
137 | Transitional cell carcinoma of the bladder (HP:0006740) | 1.62256732 |
138 | Aplasia/hypoplasia of the humerus (HP:0006507) | 1.62012263 |
139 | Long clavicles (HP:0000890) | 1.61575248 |
140 | Broad toe (HP:0001837) | 1.61259380 |
141 | Osteolytic defects of the hand bones (HP:0009699) | 1.60577844 |
142 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.60577844 |
143 | Abnormality of the ischium (HP:0003174) | 1.60053681 |
144 | Short femoral neck (HP:0100864) | 1.58759261 |
145 | Abnormality of chromosome segregation (HP:0002916) | 1.58392219 |
146 | Bicuspid aortic valve (HP:0001647) | 1.58184026 |
147 | Cortical dysplasia (HP:0002539) | 1.58155971 |
148 | Convex nasal ridge (HP:0000444) | 1.58106354 |
149 | Abnormality of the labia majora (HP:0012881) | 1.57747803 |
150 | Metaphyseal cupping (HP:0003021) | 1.57376358 |
151 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.57369049 |
152 | Drooling (HP:0002307) | 1.57108973 |
153 | Atrioventricular canal defect (HP:0006695) | 1.57036746 |
154 | Azoospermia (HP:0000027) | 1.56646380 |
155 | Metatarsus adductus (HP:0001840) | 1.56520194 |
156 | Deep philtrum (HP:0002002) | 1.56160700 |
157 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 1.55982032 |
158 | Decreased number of peripheral myelinated nerve fibers (HP:0003380) | 1.55770822 |
159 | Exercise-induced muscle cramps (HP:0003710) | 1.55662488 |
160 | Difficulty running (HP:0009046) | 1.54474401 |
161 | Broad metatarsal (HP:0001783) | 1.54437799 |
162 | Hammertoe (HP:0001765) | 1.54383438 |
163 | Abdominal situs inversus (HP:0003363) | 1.53747618 |
164 | Abnormality of abdominal situs (HP:0011620) | 1.53747618 |
165 | Protruding tongue (HP:0010808) | 1.52668850 |
166 | Mitral regurgitation (HP:0001653) | 1.52628179 |
167 | Freckling (HP:0001480) | 1.50944523 |
168 | Pulmonic stenosis (HP:0001642) | 1.50346492 |
169 | Glioma (HP:0009733) | 1.49640350 |
170 | Colon cancer (HP:0003003) | 1.49611634 |
171 | Abnormality of the astrocytes (HP:0100707) | 1.48424939 |
172 | Astrocytoma (HP:0009592) | 1.48424939 |
173 | Abnormal hair whorl (HP:0010721) | 1.48351572 |
174 | Neoplasm of striated muscle (HP:0009728) | 1.48168287 |
175 | Melanocytic nevus (HP:0000995) | 1.47919792 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 3.37100647 |
2 | CDK12 | 3.22808625 |
3 | EIF2AK1 | 3.14868700 |
4 | PDK3 | 2.92146654 |
5 | PDK4 | 2.92146654 |
6 | CDC7 | 2.78155981 |
7 | NEK2 | 2.56861032 |
8 | KSR2 | 2.48677842 |
9 | TTK | 2.45709262 |
10 | ZAK | 2.43264484 |
11 | KSR1 | 2.41777555 |
12 | PDK2 | 2.25403613 |
13 | WEE1 | 2.18153872 |
14 | MKNK2 | 2.14451938 |
15 | STK10 | 2.05709366 |
16 | TESK1 | 2.00055857 |
17 | WNK1 | 1.99795256 |
18 | STK3 | 1.92807378 |
19 | PLK4 | 1.90850486 |
20 | MELK | 1.90729203 |
21 | TNIK | 1.81093467 |
22 | DYRK3 | 1.72620723 |
23 | RAF1 | 1.72619587 |
24 | CAMK1G | 1.70293001 |
25 | LATS1 | 1.69690635 |
26 | CHEK2 | 1.66658763 |
27 | OBSCN | 1.62387208 |
28 | PNCK | 1.61233662 |
29 | PLK1 | 1.59258032 |
30 | SGK2 | 1.51486505 |
31 | CDK8 | 1.49232945 |
32 | FGFR3 | 1.49070924 |
33 | TSSK6 | 1.47459870 |
34 | TLK1 | 1.42613182 |
35 | STK38L | 1.41399721 |
36 | CASK | 1.36927759 |
37 | TGFBR2 | 1.36486760 |
38 | CAMK1D | 1.36420950 |
39 | RPS6KA4 | 1.35218790 |
40 | AURKB | 1.34536627 |
41 | ATR | 1.31703545 |
42 | BRD4 | 1.30349194 |
43 | MAP3K4 | 1.25000173 |
44 | MAP3K2 | 1.24642910 |
45 | ACVR1B | 1.21536554 |
46 | SGK3 | 1.20784853 |
47 | PLK3 | 1.18406492 |
48 | CDK7 | 1.17609296 |
49 | TGFBR1 | 1.14286333 |
50 | BRSK2 | 1.12979834 |
51 | EIF2AK2 | 1.11643356 |
52 | PIM1 | 1.09473491 |
53 | EPHA2 | 1.09254577 |
54 | CDK4 | 1.09169023 |
55 | MST4 | 1.08009619 |
56 | STK4 | 1.05153860 |
57 | SRPK1 | 1.05029401 |
58 | TTN | 1.04200481 |
59 | CDK9 | 1.00769561 |
60 | MAP3K9 | 0.99853159 |
61 | NUAK1 | 0.98813217 |
62 | NEK9 | 0.98516528 |
63 | CHEK1 | 0.98228570 |
64 | TRPM7 | 0.97382949 |
65 | ERBB3 | 0.96461738 |
66 | PRPF4B | 0.94584445 |
67 | FGFR1 | 0.94274956 |
68 | CHUK | 0.93582155 |
69 | EEF2K | 0.93411733 |
70 | ATM | 0.93255800 |
71 | PDGFRB | 0.93065333 |
72 | MAP3K10 | 0.92621015 |
73 | MTOR | 0.89283405 |
74 | BMX | 0.86535782 |
75 | CLK1 | 0.86397734 |
76 | CDK6 | 0.84723908 |
77 | MOS | 0.84592725 |
78 | MAP3K8 | 0.82957558 |
79 | TAF1 | 0.81416321 |
80 | AURKA | 0.80782508 |
81 | DDR2 | 0.80487316 |
82 | PRKD3 | 0.79357535 |
83 | SGK223 | 0.79237334 |
84 | SGK494 | 0.79237334 |
85 | TAOK1 | 0.78714598 |
86 | PDGFRA | 0.78297592 |
87 | PBK | 0.77984648 |
88 | MKNK1 | 0.74231164 |
89 | YES1 | 0.74095485 |
90 | BMPR1B | 0.72143592 |
91 | IRAK3 | 0.70086061 |
92 | PASK | 0.69084249 |
93 | MAP3K5 | 0.69056331 |
94 | NEK1 | 0.68824736 |
95 | ERBB4 | 0.66632704 |
96 | MARK1 | 0.65546522 |
97 | NLK | 0.65525642 |
98 | RPS6KB2 | 0.64889154 |
99 | TRIM28 | 0.64106879 |
100 | MAP2K3 | 0.62590931 |
101 | PAK4 | 0.61745780 |
102 | MAP3K3 | 0.61167849 |
103 | MAP3K14 | 0.61018144 |
104 | NTRK1 | 0.60658520 |
105 | DMPK | 0.59233446 |
106 | VRK1 | 0.58567089 |
107 | BRAF | 0.58030937 |
108 | ICK | 0.56121408 |
109 | EPHA3 | 0.54819702 |
110 | EIF2AK3 | 0.54220536 |
111 | TAOK2 | 0.53780137 |
112 | BRSK1 | 0.51987347 |
113 | MAP2K1 | 0.51011029 |
114 | CDK2 | 0.50696007 |
115 | FGFR2 | 0.50271578 |
116 | PAK2 | 0.49132512 |
117 | CDK1 | 0.48822778 |
118 | CSNK1G2 | 0.48001323 |
119 | SGK1 | 0.46724640 |
120 | STK24 | 0.46592872 |
121 | MAPKAPK3 | 0.45490935 |
122 | ERN1 | 0.45386570 |
123 | CSNK1G1 | 0.44106898 |
124 | PTK2B | 0.43169715 |
125 | RET | 0.42909208 |
126 | LATS2 | 0.42558609 |
127 | AKT2 | 0.42239250 |
128 | DYRK1B | 0.40164024 |
129 | MAP3K1 | 0.39772809 |
130 | MAPK10 | 0.39271933 |
131 | CAMK4 | 0.39050179 |
132 | JAK3 | 0.38718699 |
133 | MAP2K4 | 0.38533970 |
134 | MAP3K6 | 0.36909752 |
135 | FLT3 | 0.36436408 |
136 | EPHB2 | 0.35920965 |
137 | AKT3 | 0.34490438 |
138 | MAPKAPK2 | 0.33955960 |
139 | PIM2 | 0.33716745 |
140 | BCR | 0.32646524 |
141 | MET | 0.32106351 |
142 | AKT1 | 0.31208121 |
143 | MARK3 | 0.30732452 |
144 | FGFR4 | 0.30338562 |
145 | RPS6KA5 | 0.29312881 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Cell cycle_Homo sapiens_hsa04110 | 3.13952429 |
2 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.55534272 |
3 | DNA replication_Homo sapiens_hsa03030 | 2.55028437 |
4 | RNA transport_Homo sapiens_hsa03013 | 2.51161781 |
5 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.33065661 |
6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.17575416 |
7 | p53 signaling pathway_Homo sapiens_hsa04115 | 2.08829258 |
8 | Homologous recombination_Homo sapiens_hsa03440 | 2.00073087 |
9 | Basal transcription factors_Homo sapiens_hsa03022 | 1.99447288 |
10 | Base excision repair_Homo sapiens_hsa03410 | 1.99162903 |
11 | Mismatch repair_Homo sapiens_hsa03430 | 1.95357409 |
12 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.90671406 |
13 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.90275584 |
14 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.80130362 |
15 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.78663145 |
16 | Endometrial cancer_Homo sapiens_hsa05213 | 1.77131000 |
17 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.67068188 |
18 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.65843678 |
19 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.65332437 |
20 | Spliceosome_Homo sapiens_hsa03040 | 1.65265336 |
21 | Circadian rhythm_Homo sapiens_hsa04710 | 1.64809705 |
22 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.63464098 |
23 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.57283840 |
24 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.56381685 |
25 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.52975622 |
26 | Legionellosis_Homo sapiens_hsa05134 | 1.51118540 |
27 | RNA degradation_Homo sapiens_hsa03018 | 1.50810045 |
28 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.49487425 |
29 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.44671853 |
30 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.44222915 |
31 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.38443310 |
32 | Melanoma_Homo sapiens_hsa05218 | 1.35260438 |
33 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.32867047 |
34 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.31142298 |
35 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.30130238 |
36 | Adherens junction_Homo sapiens_hsa04520 | 1.27073272 |
37 | Malaria_Homo sapiens_hsa05144 | 1.25598905 |
38 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.25197266 |
39 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.21721006 |
40 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.21666037 |
41 | HTLV-I infection_Homo sapiens_hsa05166 | 1.13884465 |
42 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.13130688 |
43 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 1.12938504 |
44 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.12507562 |
45 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.11860427 |
46 | Glioma_Homo sapiens_hsa05214 | 1.10684236 |
47 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.10258594 |
48 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.09584798 |
49 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.08085714 |
50 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.06580549 |
51 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.06319260 |
52 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.04853883 |
53 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.04141122 |
54 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 1.03927384 |
55 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.03886954 |
56 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.03140292 |
57 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.99988814 |
58 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.99714645 |
59 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.98672643 |
60 | Apoptosis_Homo sapiens_hsa04210 | 0.97961748 |
61 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.93624317 |
62 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.93488861 |
63 | Bladder cancer_Homo sapiens_hsa05219 | 0.92329548 |
64 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.91247496 |
65 | Tight junction_Homo sapiens_hsa04530 | 0.91084829 |
66 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.90076646 |
67 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.88200436 |
68 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.87706282 |
69 | Gap junction_Homo sapiens_hsa04540 | 0.83977862 |
70 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.82139788 |
71 | Long-term potentiation_Homo sapiens_hsa04720 | 0.81787452 |
72 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.81395478 |
73 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.81170830 |
74 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.80489838 |
75 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.80115545 |
76 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.80096391 |
77 | Measles_Homo sapiens_hsa05162 | 0.79565526 |
78 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.79442210 |
79 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.77638947 |
80 | Influenza A_Homo sapiens_hsa05164 | 0.77618892 |
81 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.76735787 |
82 | RNA polymerase_Homo sapiens_hsa03020 | 0.76477197 |
83 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.75378322 |
84 | Focal adhesion_Homo sapiens_hsa04510 | 0.74933469 |
85 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.74028016 |
86 | Hepatitis B_Homo sapiens_hsa05161 | 0.73817503 |
87 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.73415277 |
88 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.71773566 |
89 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.70640367 |
90 | Leishmaniasis_Homo sapiens_hsa05140 | 0.70476970 |
91 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.70267324 |
92 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.69093925 |
93 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.69079645 |
94 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.68972468 |
95 | Proteasome_Homo sapiens_hsa03050 | 0.68851131 |
96 | Long-term depression_Homo sapiens_hsa04730 | 0.68737107 |
97 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.68719454 |
98 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.68021206 |
99 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.67472018 |
100 | Lysine degradation_Homo sapiens_hsa00310 | 0.67346981 |
101 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.66609740 |
102 | Prostate cancer_Homo sapiens_hsa05215 | 0.65814700 |
103 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.64095211 |
104 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.63062966 |
105 | Pathways in cancer_Homo sapiens_hsa05200 | 0.63031602 |
106 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.62969102 |
107 | Purine metabolism_Homo sapiens_hsa00230 | 0.62856647 |
108 | Viral myocarditis_Homo sapiens_hsa05416 | 0.62637301 |
109 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.61142638 |
110 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.57963211 |
111 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.57546101 |
112 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.57191483 |
113 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.56873807 |
114 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.55938339 |
115 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.55881285 |
116 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.54517292 |
117 | Amoebiasis_Homo sapiens_hsa05146 | 0.54283740 |
118 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.52831342 |
119 | Melanogenesis_Homo sapiens_hsa04916 | 0.50482404 |
120 | Axon guidance_Homo sapiens_hsa04360 | 0.49849862 |
121 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.49660693 |
122 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.48755188 |
123 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.48580123 |
124 | Alcoholism_Homo sapiens_hsa05034 | 0.48297898 |
125 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.48174611 |
126 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.47366038 |
127 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.47339004 |
128 | Colorectal cancer_Homo sapiens_hsa05210 | 0.45871078 |
129 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.45173799 |
130 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.44899918 |
131 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.43784142 |
132 | Shigellosis_Homo sapiens_hsa05131 | 0.43625775 |
133 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.43097673 |
134 | Thyroid cancer_Homo sapiens_hsa05216 | 0.42987052 |
135 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.42465771 |
136 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.41022946 |
137 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.38821352 |
138 | Salmonella infection_Homo sapiens_hsa05132 | 0.38536514 |
139 | Phagosome_Homo sapiens_hsa04145 | 0.38434486 |
140 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.37768858 |
141 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.37085309 |
142 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.36775158 |
143 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.36250170 |
144 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.35550930 |
145 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.34527917 |