FBXO40

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Members of the F-box protein family, such as FBXO40, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sarcomere organization (GO:0045214)8.93017319
2muscle filament sliding (GO:0030049)8.54467423
3actin-myosin filament sliding (GO:0033275)8.54467423
4regulation of skeletal muscle contraction (GO:0014819)7.84615523
5myofibril assembly (GO:0030239)7.54814829
6cardiac myofibril assembly (GO:0055003)7.54358332
7positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)7.47099006
8negative regulation of potassium ion transmembrane transporter activity (GO:1901017)7.19197520
9actin-mediated cell contraction (GO:0070252)7.06360005
10sarcoplasmic reticulum calcium ion transport (GO:0070296)6.87064049
11regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)6.80523953
12plasma membrane repair (GO:0001778)6.54348196
13negative regulation of potassium ion transmembrane transport (GO:1901380)6.32404044
14cardiac muscle contraction (GO:0060048)6.26972718
15tricarboxylic acid cycle (GO:0006099)6.22786726
16carnitine shuttle (GO:0006853)6.04356838
17regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO5.97832834
18regulation of relaxation of muscle (GO:1901077)5.86780853
19regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)5.82678621
20striated muscle contraction (GO:0006941)5.82265896
21regulation of actin filament-based movement (GO:1903115)5.71334792
22cardiac muscle cell development (GO:0055013)5.69972853
23actomyosin structure organization (GO:0031032)5.67235366
24regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)5.64215427
25skeletal muscle contraction (GO:0003009)5.55501099
26regulation of cell communication by electrical coupling (GO:0010649)5.49969511
27cardiac cell development (GO:0055006)5.34005921
28actin filament-based movement (GO:0030048)5.30667580
29regulation of acyl-CoA biosynthetic process (GO:0050812)5.29569868
30response to stimulus involved in regulation of muscle adaptation (GO:0014874)5.29112576
31regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)5.26007382
32fatty acid transmembrane transport (GO:1902001)5.25258801
33regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)5.10124608
34skeletal muscle adaptation (GO:0043501)5.01445203
35cardiac muscle hypertrophy (GO:0003300)5.01273382
36cardiac muscle tissue morphogenesis (GO:0055008)4.96074480
37creatine metabolic process (GO:0006600)4.96045436
38ventricular cardiac muscle cell action potential (GO:0086005)4.88780294
39striated muscle hypertrophy (GO:0014897)4.86373538
40regulation of coenzyme metabolic process (GO:0051196)4.80694491
41regulation of cofactor metabolic process (GO:0051193)4.80694491
42regulation of striated muscle contraction (GO:0006942)4.73438036
43heart process (GO:0003015)4.73177710
44heart contraction (GO:0060047)4.73177710
45adult heart development (GO:0007512)4.72315053
46regulation of sarcomere organization (GO:0060297)4.59329042
47muscle tissue morphogenesis (GO:0060415)4.59223752
48carnitine transmembrane transport (GO:1902603)4.55532754
49bundle of His cell to Purkinje myocyte communication (GO:0086069)4.55071133
50skeletal muscle fiber development (GO:0048741)4.54521585
51myotube cell development (GO:0014904)4.39134005
52regulation of calcineurin-NFAT signaling cascade (GO:0070884)4.37682616
53muscle hypertrophy (GO:0014896)4.30477998
54ventricular cardiac muscle tissue morphogenesis (GO:0055010)4.29999478
55amino-acid betaine transport (GO:0015838)4.27681347
56carnitine transport (GO:0015879)4.27681347
57regulation of membrane repolarization (GO:0060306)4.25448718
58heart trabecula formation (GO:0060347)4.21464841
59response to inactivity (GO:0014854)4.19209040
60muscle contraction (GO:0006936)4.17761714
612-oxoglutarate metabolic process (GO:0006103)4.14003146
62positive regulation of calcium ion transmembrane transporter activity (GO:1901021)4.04270104
63striated muscle adaptation (GO:0014888)3.98637923
64glycogen catabolic process (GO:0005980)3.96232670
65NADH metabolic process (GO:0006734)3.95518342
66skeletal muscle tissue development (GO:0007519)3.93575096
67membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.93149320
68regulation of sulfur metabolic process (GO:0042762)3.92948423
69cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.89128969
70cell communication involved in cardiac conduction (GO:0086065)3.87780158
71muscle system process (GO:0003012)3.85902894
72muscle cell cellular homeostasis (GO:0046716)3.81829203
73negative regulation of calcium ion transmembrane transport (GO:1903170)3.81828976
74negative regulation of calcium ion transmembrane transporter activity (GO:1901020)3.81828976
75striated muscle atrophy (GO:0014891)3.80982335
76striated muscle cell development (GO:0055002)3.77522895
77regulation of sequestering of triglyceride (GO:0010889)3.77206692
78relaxation of cardiac muscle (GO:0055119)3.76993829
79regulation of the force of heart contraction (GO:0002026)3.76339084
80response to muscle activity (GO:0014850)3.74436811
81mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.70974745
82glucan catabolic process (GO:0009251)3.69870846
83mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.65636351
84pyrimidine ribonucleoside catabolic process (GO:0046133)3.64309541
85negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.64053992
86response to caffeine (GO:0031000)3.60437272
87oxidative phosphorylation (GO:0006119)3.59711193
88cardiac muscle hypertrophy in response to stress (GO:0014898)3.58071977
89muscle hypertrophy in response to stress (GO:0003299)3.58071977
90cardiac muscle adaptation (GO:0014887)3.58071977
91respiratory electron transport chain (GO:0022904)3.57442248
92relaxation of muscle (GO:0090075)3.54872478
93cardiac muscle cell action potential (GO:0086001)3.54600604
94regulation of cardiac muscle contraction (GO:0055117)3.54330734
95positive regulation of cation channel activity (GO:2001259)3.54134177
96regulation of calcium ion transmembrane transporter activity (GO:1901019)3.53898489
97regulation of calcium ion transmembrane transport (GO:1903169)3.53898489
98cardiac muscle cell action potential involved in contraction (GO:0086002)3.51796525
99muscle adaptation (GO:0043500)3.51327864
100regulation of cardiac muscle cell contraction (GO:0086004)3.50700351
101regulation of muscle system process (GO:0090257)3.49251921
102aspartate family amino acid catabolic process (GO:0009068)3.48417091
103regulation of ATP catabolic process (GO:1903289)3.47690900
104regulation of ATPase activity (GO:0043462)3.47690900
105muscle fiber development (GO:0048747)3.47550959
106regulation of muscle contraction (GO:0006937)3.46448683
107electron transport chain (GO:0022900)3.45934173
108cellular polysaccharide catabolic process (GO:0044247)3.45703169
109negative regulation of potassium ion transport (GO:0043267)3.42347149
110lysine catabolic process (GO:0006554)3.39396323
111lysine metabolic process (GO:0006553)3.39396323
112regulation of heart rate (GO:0002027)3.38873671
113skeletal muscle tissue regeneration (GO:0043403)3.36816943
114glycogen biosynthetic process (GO:0005978)3.36116631
115glucan biosynthetic process (GO:0009250)3.36116631
116polysaccharide catabolic process (GO:0000272)3.34656188
117ATP synthesis coupled proton transport (GO:0015986)3.34168616
118muscle structure development (GO:0061061)3.29831575
119muscle cell development (GO:0055001)3.27697519
120muscle organ development (GO:0007517)3.27102344

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse6.50650624
2EP300_21415370_ChIP-Seq_HL-1_Mouse4.26097332
3ESRRB_18555785_ChIP-Seq_MESCs_Mouse4.20287795
4TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse4.13897574
5BP1_19119308_ChIP-ChIP_Hs578T_Human3.97712864
6TBX20_22328084_ChIP-Seq_HEART_Mouse3.92913147
7TBX20_22080862_ChIP-Seq_HEART_Mouse3.92913147
8TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.60802382
9ESR1_20079471_ChIP-ChIP_T-47D_Human3.34292723
10ZNF263_19887448_ChIP-Seq_K562_Human2.99227599
11MEF2A_21415370_ChIP-Seq_HL-1_Mouse2.96634112
12RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.87993367
13GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.81742780
14ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.66871970
15RARG_19884340_ChIP-ChIP_MEFs_Mouse2.63764621
16CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.45421768
17PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.30761488
18GATA4_21415370_ChIP-Seq_HL-1_Mouse2.24497814
19CDX2_19796622_ChIP-Seq_MESCs_Mouse2.23830806
20GBX2_23144817_ChIP-Seq_PC3_Human2.23786645
21NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.21045754
22VDR_22108803_ChIP-Seq_LS180_Human2.18298171
23THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.95830585
24PPARA_22158963_ChIP-Seq_LIVER_Mouse1.87389195
25EZH2_22144423_ChIP-Seq_EOC_Human1.77109677
26ESR2_21235772_ChIP-Seq_MCF-7_Human1.74750573
27LXR_22158963_ChIP-Seq_LIVER_Mouse1.67611992
28NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.66665464
29RXR_22158963_ChIP-Seq_LIVER_Mouse1.63024953
30GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.61847996
31EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.60791957
32PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.60098997
33IGF1R_20145208_ChIP-Seq_DFB_Human1.58366229
34CLOCK_20551151_ChIP-Seq_293T_Human1.58083006
35EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.55587587
36TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.53940152
37ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.52106805
38FLI1_27457419_Chip-Seq_LIVER_Mouse1.49207258
39BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.47244211
40PCGF2_27294783_Chip-Seq_ESCs_Mouse1.45615370
41FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.45201106
42CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.42527754
43SUZ12_27294783_Chip-Seq_NPCs_Mouse1.40044597
44ZFP57_27257070_Chip-Seq_ESCs_Mouse1.33068987
45* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.32065142
46EZH2_27294783_Chip-Seq_NPCs_Mouse1.30934638
47POU3F2_20337985_ChIP-ChIP_501MEL_Human1.30127703
48CTCF_27219007_Chip-Seq_Bcells_Human1.28698626
49CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.27097067
50SMAD4_21799915_ChIP-Seq_A2780_Human1.26231988
51PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.25227908
52GATA1_22025678_ChIP-Seq_K562_Human1.23418064
53NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.22403138
54PCGF2_27294783_Chip-Seq_NPCs_Mouse1.21983003
55CBX2_27304074_Chip-Seq_ESCs_Mouse1.21923814
56ER_23166858_ChIP-Seq_MCF-7_Human1.21728475
57PPAR_26484153_Chip-Seq_NCI-H1993_Human1.20856801
58KDM2B_26808549_Chip-Seq_SUP-B15_Human1.20328895
59CRX_20693478_ChIP-Seq_RETINA_Mouse1.19397191
60TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.17876548
61AR_21572438_ChIP-Seq_LNCaP_Human1.17223069
62PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.16411739
63ESR1_21235772_ChIP-Seq_MCF-7_Human1.14680496
64SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.11746026
65CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.11604307
66KDM2B_26808549_Chip-Seq_DND41_Human1.09544005
67ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.09026045
68NR3C1_21868756_ChIP-Seq_MCF10A_Human1.08916589
69DROSHA_22980978_ChIP-Seq_HELA_Human1.08754582
70OCT4_21477851_ChIP-Seq_ESCs_Mouse1.08591424
71TP63_22573176_ChIP-Seq_HFKS_Human1.07784043
72NRF2_20460467_ChIP-Seq_MEFs_Mouse1.06966425
73NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.06966425
74TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.06145363
75TCF4_23295773_ChIP-Seq_U87_Human1.05653146
76SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.02823830
77NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.02799203
78E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.02451296
79RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.01919134
80EZH2_27294783_Chip-Seq_ESCs_Mouse1.01729903
81SOX2_19829295_ChIP-Seq_ESCs_Human1.00818920
82NANOG_19829295_ChIP-Seq_ESCs_Human1.00818920
83OCT4_20526341_ChIP-Seq_ESCs_Human1.00694001
84CTCF_21964334_ChIP-Seq_BJAB-B_Human1.00060993
85FOXA2_19822575_ChIP-Seq_HepG2_Human0.99951167
86NFIB_24661679_ChIP-Seq_LUNG_Mouse0.99889749
87GATA1_19941826_ChIP-Seq_K562_Human0.99651703
88TAF15_26573619_Chip-Seq_HEK293_Human0.98754612
89SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.98575398
90ATF3_27146783_Chip-Seq_COLON_Human0.98456334
91NFE2_27457419_Chip-Seq_LIVER_Mouse0.98024436
92RACK7_27058665_Chip-Seq_MCF-7_Human0.97403542
93FOXH1_21741376_ChIP-Seq_ESCs_Human0.97178826
94GATA2_21666600_ChIP-Seq_HMVEC_Human0.96186237
95AUTS2_25519132_ChIP-Seq_293T-REX_Human0.96082981
96SMC3_22415368_ChIP-Seq_MEFs_Mouse0.95192563
97ZNF274_21170338_ChIP-Seq_K562_Hela0.94874243
98MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.94081850
99SPI1_20517297_ChIP-Seq_HL60_Human0.93852045
100HTT_18923047_ChIP-ChIP_STHdh_Human0.93536596
101P68_20966046_ChIP-Seq_HELA_Human0.93171764
102STAT3_1855785_ChIP-Seq_MESCs_Mouse0.93048673
103SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.91473520
104TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.91449022
105KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.91065350
106LXR_22292898_ChIP-Seq_THP-1_Human0.90977020
107TOP2B_26459242_ChIP-Seq_MCF-7_Human0.89881012
108RUNX1_27514584_Chip-Seq_MCF-7_Human0.89878410
109AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.89497630
110GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.89208872
111KLF5_20875108_ChIP-Seq_MESCs_Mouse0.88633604
112GATA2_19941826_ChIP-Seq_K562_Human0.87564224
113CTCF_21964334_Chip-Seq_Bcells_Human0.87274733
114NR3C1_23031785_ChIP-Seq_PC12_Mouse0.87000649
115CJUN_26792858_Chip-Seq_BT549_Human0.86605296
116STAT3_23295773_ChIP-Seq_U87_Human0.86358354
117UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.86275117
118GATA1_19941827_ChIP-Seq_MEL_Mouse0.86267846
119LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.85877547
120PIAS1_25552417_ChIP-Seq_VCAP_Human0.85620558
121TBL1_22424771_ChIP-Seq_293T_Human0.85226320
122ISL1_27105846_Chip-Seq_CPCs_Mouse0.84542291
123SOX9_24532713_ChIP-Seq_HFSC_Mouse0.83911828
124SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.83531488
125CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.83060647
126GATA1_19941827_ChIP-Seq_MEL86_Mouse0.82926418
127CTNNB1_20460455_ChIP-Seq_HCT116_Human0.82698185
128NFYB_21822215_ChIP-Seq_K562_Human0.82697373
129CBP_20019798_ChIP-Seq_JUKART_Human0.82691602
130IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.82691602
131SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.82293070
132TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.81992712
133PHF8_20622853_ChIP-Seq_HELA_Human0.81831707
134FLI1_21867929_ChIP-Seq_TH2_Mouse0.81819103
135E2F1_18555785_Chip-Seq_ESCs_Mouse0.80514978
136ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.80132349
137SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.79794581
138ELK3_25401928_ChIP-Seq_HUVEC_Human0.79541621
139SMC1_22415368_ChIP-Seq_MEFs_Mouse0.79287289
140OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.79067791
141SMAD3_21741376_ChIP-Seq_HESCs_Human0.78860779
142EZH2_27304074_Chip-Seq_ESCs_Mouse0.78769827
143PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.78666269
144SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.78651451
145RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.77286586
146P63_26484246_Chip-Seq_KERATINOCYTES_Human0.77262620
147SMAD3_21741376_ChIP-Seq_EPCs_Human0.76924112
148MTF2_20144788_ChIP-Seq_MESCs_Mouse0.76646402
149SOX2_21211035_ChIP-Seq_LN229_Gbm0.76048806
150SMAD4_21741376_ChIP-Seq_EPCs_Human0.75803254
151EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.75773881
152UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.74958838
153EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.74324871
154TDRD3_21172665_ChIP-Seq_MCF-7_Human0.74021354
155CREB1_26743006_Chip-Seq_LNCaP_Human0.73126433
156TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.73036934
157SA1_27219007_Chip-Seq_Bcells_Human0.72633769
158DNAJC2_21179169_ChIP-ChIP_NT2_Human0.72394912
159BCAT_22108803_ChIP-Seq_LS180_Human0.72233119
160SMAD4_21741376_ChIP-Seq_HESCs_Human0.72122720
161GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.72024728
162HIF1A_21447827_ChIP-Seq_MCF-7_Human0.71036518
163YY1_22570637_ChIP-Seq_MALME-3M_Human0.70760058
164ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.70635978
165BCL6_27268052_Chip-Seq_Bcells_Human0.70066479

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003646_muscle_fatigue6.42437367
2MP0002837_dystrophic_cardiac_calcinosis6.36322310
3MP0000751_myopathy5.45842795
4MP0004084_abnormal_cardiac_muscle4.82073951
5MP0000749_muscle_degeneration4.69470688
6MP0004036_abnormal_muscle_relaxation4.34346034
7MP0004215_abnormal_myocardial_fiber4.11215935
8MP0004145_abnormal_muscle_electrophysio3.97103690
9MP0005330_cardiomyopathy3.53927314
10MP0004087_abnormal_muscle_fiber3.32208072
11MP0002106_abnormal_muscle_physiology3.10082114
12MP0004130_abnormal_muscle_cell2.98525662
13MP0000750_abnormal_muscle_regeneration2.96961722
14MP0005620_abnormal_muscle_contractility2.92113348
15MP0002269_muscular_atrophy2.79920046
16MP0000747_muscle_weakness2.76470653
17MP0002972_abnormal_cardiac_muscle2.74567012
18MP0005369_muscle_phenotype2.53447415
19MP0000759_abnormal_skeletal_muscle2.53346985
20MP0008775_abnormal_heart_ventricle2.43897630
21MP0003137_abnormal_impulse_conducting2.40109684
22MP0010630_abnormal_cardiac_muscle2.33909422
23MP0004484_altered_response_of2.30803996
24MP0005385_cardiovascular_system_phenoty2.25435658
25MP0001544_abnormal_cardiovascular_syste2.25435658
26MP0004233_abnormal_muscle_weight2.01430454
27MP0003221_abnormal_cardiomyocyte_apopto1.95901588
28MP0006036_abnormal_mitochondrial_physio1.92510221
29MP0006138_congestive_heart_failure1.89090122
30MP0004510_myositis1.76922305
31MP0003828_pulmonary_edema1.70372102
32MP0002332_abnormal_exercise_endurance1.68012639
33MP0004085_abnormal_heartbeat1.66166906
34MP0005666_abnormal_adipose_tissue1.56238141
35MP0002127_abnormal_cardiovascular_syste1.41955417
36MP0003950_abnormal_plasma_membrane1.39417253
37MP0005670_abnormal_white_adipose1.28593362
38MP0004185_abnormal_adipocyte_glucose1.26214432
39MP0002108_abnormal_muscle_morphology1.21473065
40MP0001661_extended_life_span1.19573709
41MP0006035_abnormal_mitochondrial_morpho1.12588591
42MP0000733_abnormal_muscle_development1.10060881
43MP0000343_altered_response_to1.08246005
44MP0005375_adipose_tissue_phenotype1.06662904
45MP0004270_analgesia1.06423423
46MP0000266_abnormal_heart_morphology1.00756645
47MP0003806_abnormal_nucleotide_metabolis1.00070840
48MP0003567_abnormal_fetal_cardiomyocyte0.96752818
49MP0005266_abnormal_metabolism0.93393123
50MP0002234_abnormal_pharynx_morphology0.91324139
51MP0005165_increased_susceptibility_to0.87684555
52MP0004043_abnormal_pH_regulation0.84491601
53MP0002971_abnormal_brown_adipose0.83747042
54MP0010368_abnormal_lymphatic_system0.78751264
55MP0000372_irregular_coat_pigmentation0.77667830
56MP0000230_abnormal_systemic_arterial0.72068810
57MP0000013_abnormal_adipose_tissue0.71354883
58MP0003705_abnormal_hypodermis_morpholog0.70975320
59MP0003279_aneurysm0.67024246
60MP0002128_abnormal_blood_circulation0.65931636
61MP0004147_increased_porphyrin_level0.63696320
62MP0002638_abnormal_pupillary_reflex0.63532894
63MP0005451_abnormal_body_composition0.62109069
64MP0000003_abnormal_adipose_tissue0.60157714
65MP0002078_abnormal_glucose_homeostasis0.57332202
66MP0005319_abnormal_enzyme/_coenzyme0.56096195
67MP0005167_abnormal_blood-brain_barrier0.55621347
68MP0008961_abnormal_basal_metabolism0.54838042
69MP0003566_abnormal_cell_adhesion0.49896312
70MP0004142_abnormal_muscle_tone0.49082356
71MP0008569_lethality_at_weaning0.48661375
72MP0001879_abnormal_lymphatic_vessel0.45303588
73MP0003195_calcinosis0.45266966
74MP0002909_abnormal_adrenal_gland0.44169551
75MP0001984_abnormal_olfaction0.43766689
76MP0005334_abnormal_fat_pad0.42412967
77MP0000767_abnormal_smooth_muscle0.42073986
78MP0005187_abnormal_penis_morphology0.41984978
79MP0005623_abnormal_meninges_morphology0.38444024
80MP0005535_abnormal_body_temperature0.38217418
81MP0003045_fibrosis0.37942415
82MP0005584_abnormal_enzyme/coenzyme_acti0.37673631
83MP0005083_abnormal_biliary_tract0.37624958
84MP0005386_behavior/neurological_phenoty0.36747653
85MP0004924_abnormal_behavior0.36747653
86MP0004134_abnormal_chest_morphology0.35540630
87MP0003879_abnormal_hair_cell0.35095223
88MP0003656_abnormal_erythrocyte_physiolo0.34923688
89MP0002118_abnormal_lipid_homeostasis0.34642430
90MP0005275_abnormal_skin_tensile0.34076214
91MP0005332_abnormal_amino_acid0.33180207
92MP0009840_abnormal_foam_cell0.32211788
93MP0002925_abnormal_cardiovascular_devel0.31874693
94MP0005085_abnormal_gallbladder_physiolo0.29404835
95MP0009115_abnormal_fat_cell0.28882621
96MP0006276_abnormal_autonomic_nervous0.28184757
97MP0003948_abnormal_gas_homeostasis0.27968323
98MP0005423_abnormal_somatic_nervous0.26252958
99MP0001614_abnormal_blood_vessel0.26058436
100MP0008438_abnormal_cutaneous_collagen0.25319464
101MP0005452_abnormal_adipose_tissue0.24663712
102MP0001784_abnormal_fluid_regulation0.24194437
103MP0002066_abnormal_motor_capabilities/c0.22447886
104MP0001853_heart_inflammation0.22190046
105MP0003984_embryonic_growth_retardation0.22175295
106MP0002876_abnormal_thyroid_physiology0.21711425
107MP0005376_homeostasis/metabolism_phenot0.21470367
108MP0002088_abnormal_embryonic_growth/wei0.21115374
109MP0001765_abnormal_ion_homeostasis0.20990737
110MP0003136_yellow_coat_color0.20924524
111MP0002822_catalepsy0.19482660
112MP0001299_abnormal_eye_distance/0.18586017
113MP0002067_abnormal_sensory_capabilities0.18534964
114MP0001727_abnormal_embryo_implantation0.18529809
115MP0002272_abnormal_nervous_system0.18497348
116MP0002734_abnormal_mechanical_nocicepti0.18161381
117MP0009384_cardiac_valve_regurgitation0.18079501
118MP0001529_abnormal_vocalization0.17089155
119MP0002970_abnormal_white_adipose0.17024947
120MP0000579_abnormal_nail_morphology0.16919474
121MP0009780_abnormal_chondrocyte_physiolo0.16869335
122MP0009672_abnormal_birth_weight0.15808846
123MP0005166_decreased_susceptibility_to0.15291290
124MP0002114_abnormal_axial_skeleton0.15030981
125MP0001486_abnormal_startle_reflex0.14765363

Predicted human phenotypes

RankGene SetZ-score
1Exercise-induced myalgia (HP:0003738)7.35186939
2Exercise-induced muscle cramps (HP:0003710)7.09762308
3Calf muscle hypertrophy (HP:0008981)6.89946480
4Sudden death (HP:0001699)6.86185494
5Muscle hypertrophy of the lower extremities (HP:0008968)6.82096880
6Muscle fiber splitting (HP:0003555)6.17689641
7Ventricular tachycardia (HP:0004756)5.75177334
8Myoglobinuria (HP:0002913)5.54985522
9Hyporeflexia of lower limbs (HP:0002600)5.46124758
10Muscle fiber inclusion bodies (HP:0100299)5.41439322
11Abnormality of the calf musculature (HP:0001430)5.29650922
12Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)5.24568895
13Subaortic stenosis (HP:0001682)4.69864107
14Abnormality of the left ventricular outflow tract (HP:0011103)4.69864107
15Atrial fibrillation (HP:0005110)4.68638172
16EMG: myopathic abnormalities (HP:0003458)4.65537375
17Difficulty running (HP:0009046)4.55144179
18Nemaline bodies (HP:0003798)4.51024063
19Rhabdomyolysis (HP:0003201)4.42192140
20Lipoatrophy (HP:0100578)4.41311070
21Increased connective tissue (HP:0009025)4.40686303
22Primary atrial arrhythmia (HP:0001692)4.37223018
23Type 1 muscle fiber predominance (HP:0003803)4.29592097
24Supraventricular tachycardia (HP:0004755)4.21930860
25Supraventricular arrhythmia (HP:0005115)4.12571134
26Right ventricular cardiomyopathy (HP:0011663)4.06250814
27Myotonia (HP:0002486)3.91531823
28Asymmetric septal hypertrophy (HP:0001670)3.87970206
29Bundle branch block (HP:0011710)3.87007042
30Dilated cardiomyopathy (HP:0001644)3.79279806
31Syncope (HP:0001279)3.70167991
32Palpitations (HP:0001962)3.59725730
33Muscle stiffness (HP:0003552)3.57765481
34Prolonged QT interval (HP:0001657)3.32850193
35Difficulty climbing stairs (HP:0003551)3.32456687
36Ventricular arrhythmia (HP:0004308)3.26310564
37Distal arthrogryposis (HP:0005684)3.23290116
38Heart block (HP:0012722)3.20793707
39Myopathic facies (HP:0002058)3.15884377
40Round ear (HP:0100830)3.03250276
41Abnormal atrioventricular conduction (HP:0005150)3.02148307
42Areflexia of lower limbs (HP:0002522)3.00279342
43Abnormality of skeletal muscle fiber size (HP:0012084)2.98433362
44Increased variability in muscle fiber diameter (HP:0003557)2.98182068
45Atrioventricular block (HP:0001678)2.95835774
46Neck muscle weakness (HP:0000467)2.91820385
47Distal lower limb muscle weakness (HP:0009053)2.89631551
48Rimmed vacuoles (HP:0003805)2.81711770
49Ventricular fibrillation (HP:0001663)2.73483899
50Ulnar deviation of the wrist (HP:0003049)2.61683961
51Ketoacidosis (HP:0001993)2.61579741
52Abnormal finger flexion creases (HP:0006143)2.46122926
53Limb-girdle muscle atrophy (HP:0003797)2.45051299
54Left ventricular hypertrophy (HP:0001712)2.42492764
55Hepatic necrosis (HP:0002605)2.42134723
56Abnormal mitochondria in muscle tissue (HP:0008316)2.40786872
57Bulbar palsy (HP:0001283)2.40563197
58Abnormal EKG (HP:0003115)2.38566377
59Malignant hyperthermia (HP:0002047)2.36352062
60Hypoplastic ischia (HP:0003175)2.34615714
61Acute necrotizing encephalopathy (HP:0006965)2.33286366
62Muscular dystrophy (HP:0003560)2.31977640
63Ragged-red muscle fibers (HP:0003200)2.30410277
64EMG: neuropathic changes (HP:0003445)2.30117144
65Hypoglycemic coma (HP:0001325)2.23542919
66Generalized muscle weakness (HP:0003324)2.20038068
67Increased muscle lipid content (HP:0009058)2.15987658
68Palmoplantar keratoderma (HP:0000982)2.15426699
69Facial diplegia (HP:0001349)2.15153150
70Abnormality of fatty-acid metabolism (HP:0004359)2.14712739
71Testicular atrophy (HP:0000029)2.14361650
72Weak cry (HP:0001612)2.13819887
73Distal lower limb amyotrophy (HP:0008944)2.12637811
74Frequent falls (HP:0002359)2.12494995
75Acute encephalopathy (HP:0006846)2.10369686
76Gowers sign (HP:0003391)2.10007758
77Dicarboxylic aciduria (HP:0003215)2.09055206
78Abnormality of dicarboxylic acid metabolism (HP:0010995)2.09055206
79Hepatocellular necrosis (HP:0001404)2.07196095
80Mildly elevated creatine phosphokinase (HP:0008180)2.05679605
81Slender build (HP:0001533)2.05675628
82Ketosis (HP:0001946)2.04712221
83Abnormality of the ischium (HP:0003174)2.04480934
84Abnormality of the shoulder girdle musculature (HP:0001435)2.00575854
85Proximal amyotrophy (HP:0007126)2.00136884
86Calcaneovalgus deformity (HP:0001848)1.99122321
87Cerebral edema (HP:0002181)1.98340774
88Exercise intolerance (HP:0003546)1.97960533
89Waddling gait (HP:0002515)1.97253481
90Absent phalangeal crease (HP:0006109)1.95905840
91Abnormality of alanine metabolism (HP:0010916)1.95792910
92Hyperalaninemia (HP:0003348)1.95792910
93Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.95792910
94Fetal akinesia sequence (HP:0001989)1.95034231
95Scapular winging (HP:0003691)1.94918513
96Progressive muscle weakness (HP:0003323)1.94255753
97Progressive macrocephaly (HP:0004481)1.93877751
98Abnormality of the neuromuscular junction (HP:0003398)1.93035180
99Fatigable weakness (HP:0003473)1.93035180
100Conjunctival hamartoma (HP:0100780)1.92978137
101Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.91669208
102Abnormality of the foot musculature (HP:0001436)1.91472358
103Hip contracture (HP:0003273)1.91317154
104Foot dorsiflexor weakness (HP:0009027)1.89965372
105Spinal rigidity (HP:0003306)1.88328267
106Increased intramyocellular lipid droplets (HP:0012240)1.88052042
107Mitochondrial inheritance (HP:0001427)1.87897256
108Lower limb amyotrophy (HP:0007210)1.85970084
109Limb-girdle muscle weakness (HP:0003325)1.83837154
110Increased CSF lactate (HP:0002490)1.82906914
111Respiratory insufficiency due to muscle weakness (HP:0002747)1.81899545
112Deformed tarsal bones (HP:0008119)1.80533362
113Steppage gait (HP:0003376)1.79008129
114Hyperkalemia (HP:0002153)1.77978272
115Lactic acidosis (HP:0003128)1.77889412
116Centrally nucleated skeletal muscle fibers (HP:0003687)1.77576371
117Oligomenorrhea (HP:0000876)1.69975891
118Abnormality of the hip-girdle musculature (HP:0001445)1.63399711
119Abnormality of the musculature of the pelvis (HP:0001469)1.63399711
120Toxemia of pregnancy (HP:0100603)1.51062003
121Shoulder girdle muscle weakness (HP:0003547)1.49961800
122Pelvic girdle muscle weakness (HP:0003749)1.49716809
123Insulin-resistant diabetes mellitus (HP:0000831)1.46810123
124Abnormality of the calcaneus (HP:0008364)1.45925616

Predicted kinase interactions (KEA)

RankGene SetZ-score
1OBSCN6.37729290
2TTN6.31606258
3PHKG24.79778870
4PHKG14.79778870
5PDK43.27750131
6PDK33.27750131
7DMPK2.81378772
8LMTK22.73248592
9BCKDK2.52643603
10TRIB32.44271295
11NEK12.42865794
12MYLK2.36992658
13MUSK2.33329501
14PKN22.30080425
15PINK12.27032841
16PIK3CA2.12612263
17PDK22.01472340
18NME11.71104610
19MAP2K31.61328884
20STK241.54771424
21TIE11.53758643
22MAP3K71.53416029
23MARK11.37177861
24PIK3CG1.30515286
25MAPK121.25614063
26LIMK11.19357897
27GRK71.14221799
28ZAK1.01635813
29PRKAA21.00415296
30PRKAA10.99349605
31CAMK2D0.99107887
32PRKD10.99027888
33MAPKAPK30.94182911
34PAK30.92220148
35ILK0.87961645
36INSRR0.87384598
37TRPM70.83335217
38STK38L0.83067701
39WNK40.81286372
40MAP3K30.78389509
41CCNB10.77865400
42ERBB30.76242985
43ROCK10.75695780
44MAP3K50.73978472
45NEK90.73578264
46RIPK10.72791511
47PKN10.68892347
48MAP2K40.68514227
49FLT30.60430520
50EPHB10.60369988
51STK40.57961166
52CDC42BPA0.53716610
53STK380.52298570
54MAPK40.51951981
55CAMK2B0.51773767
56CAMK40.51374558
57MAP2K60.51077452
58FRK0.49610348
59WNK10.48821636
60AKT20.48572623
61MAP2K10.47240901
62PDGFRA0.46935995
63MOS0.46021532
64PRKACB0.44278441
65CAMK2G0.42304872
66TGFBR20.41330154
67LATS10.39719344
68CAMK2A0.39673261
69SIK10.38764643
70ROCK20.37906429
71SGK20.36320766
72EPHA30.36096325
73PRKACA0.34985622
74MAPK110.34674486
75DYRK1B0.34397663
76DAPK30.34231701
77PDPK10.33969722
78PTK60.33551986
79KDR0.33143769
80PRKACG0.31952200
81TAOK10.31193357
82RPS6KC10.30998470
83RPS6KL10.30998470
84MAPK130.30614257
85PDK10.28324588
86CAMK10.28286487
87PTK2B0.27838715
88LATS20.26309007
89STK110.26008474
90ICK0.25801957
91SGK10.25767115
92RPS6KA60.25063179
93SGK30.24182296
94DAPK20.23020993
95RPS6KA10.22528610
96MARK30.22462522
97KSR20.21741919
98PRKG10.21560776
99NLK0.21403503
100STK390.20774061
101MAP3K130.20767863
102RPS6KA30.18776085
103MAPK100.18770691
104MAP3K60.18500319
105MAP3K110.18108684
106PRKCH0.18006559
107MTOR0.17362783
108TNIK0.17322589
109JAK10.17165439
110PRKCE0.16631793
111RET0.15778877
112MAP3K40.15379083
113MAP3K10.15122457
114FGFR40.15085340
115ZAP700.15078013
116RPS6KB10.14734443
117MAPK70.14046819
118EEF2K0.13630106
119LRRK20.13254048
120SGK2230.12727344
121SGK4940.12727344
122TAOK20.10969548
123BLK0.10614776
124TBK10.10210941
125JAK20.10072538
126PRKD30.09893507
127CAMK1G0.09300153
128PAK60.09078977
129MARK20.05939664
130ADRBK10.04952171
131FGFR30.04839950
132PRKCA0.04616692
133MAPK90.04537705
134PRKCQ0.02549214

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000205.67359504
22-Oxocarboxylic acid metabolism_Homo sapiens_hsa012104.26739380
3Cardiac muscle contraction_Homo sapiens_hsa042603.96054721
4Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054103.73484224
5Dilated cardiomyopathy_Homo sapiens_hsa054143.59670328
6Propanoate metabolism_Homo sapiens_hsa006403.40852725
7Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.40633061
8Fatty acid degradation_Homo sapiens_hsa000712.88467309
9Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.68450856
10Parkinsons disease_Homo sapiens_hsa050122.67664283
11Oxidative phosphorylation_Homo sapiens_hsa001902.56567844
12Carbon metabolism_Homo sapiens_hsa012002.52140533
13Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.47553441
14Fatty acid metabolism_Homo sapiens_hsa012122.16813060
15Alzheimers disease_Homo sapiens_hsa050102.03827717
16Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.96237222
17Pyruvate metabolism_Homo sapiens_hsa006201.94286489
18Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.66186439
19Viral myocarditis_Homo sapiens_hsa054161.63886778
20Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.60292532
21Starch and sucrose metabolism_Homo sapiens_hsa005001.60134599
22Butanoate metabolism_Homo sapiens_hsa006501.56680016
23Huntingtons disease_Homo sapiens_hsa050161.55106001
24Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.45834224
25Insulin resistance_Homo sapiens_hsa049311.34598408
26Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.31293725
27Glucagon signaling pathway_Homo sapiens_hsa049221.28849849
28Biosynthesis of amino acids_Homo sapiens_hsa012301.24960957
29Adipocytokine signaling pathway_Homo sapiens_hsa049201.21075671
30Insulin signaling pathway_Homo sapiens_hsa049101.19263603
31PPAR signaling pathway_Homo sapiens_hsa033201.15305655
32Fatty acid elongation_Homo sapiens_hsa000621.14484215
33Arginine biosynthesis_Homo sapiens_hsa002200.99817041
34Tryptophan metabolism_Homo sapiens_hsa003800.97280508
35cGMP-PKG signaling pathway_Homo sapiens_hsa040220.95365551
36Nitrogen metabolism_Homo sapiens_hsa009100.94169551
37Arginine and proline metabolism_Homo sapiens_hsa003300.94059476
38AMPK signaling pathway_Homo sapiens_hsa041520.93451135
39beta-Alanine metabolism_Homo sapiens_hsa004100.90986793
40Oxytocin signaling pathway_Homo sapiens_hsa049210.87005778
41Calcium signaling pathway_Homo sapiens_hsa040200.85731345
42Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.84573268
43Galactose metabolism_Homo sapiens_hsa000520.81764508
44Lysine degradation_Homo sapiens_hsa003100.81046267
45Circadian rhythm_Homo sapiens_hsa047100.79498619
46Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.71328897
47Fructose and mannose metabolism_Homo sapiens_hsa000510.69477652
48Peroxisome_Homo sapiens_hsa041460.68732769
49Focal adhesion_Homo sapiens_hsa045100.66052679
50HIF-1 signaling pathway_Homo sapiens_hsa040660.64583807
51Type II diabetes mellitus_Homo sapiens_hsa049300.61380977
52Vascular smooth muscle contraction_Homo sapiens_hsa042700.59607251
53Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.59042839
54Tight junction_Homo sapiens_hsa045300.54725878
55Salivary secretion_Homo sapiens_hsa049700.53917808
56Fatty acid biosynthesis_Homo sapiens_hsa000610.53686010
57Phenylalanine metabolism_Homo sapiens_hsa003600.52805296
58Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.52786613
59Central carbon metabolism in cancer_Homo sapiens_hsa052300.51342931
60Longevity regulating pathway - mammal_Homo sapiens_hsa042110.50746229
61Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.50651865
62Regulation of autophagy_Homo sapiens_hsa041400.48504319
63Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.43821253
64Gastric acid secretion_Homo sapiens_hsa049710.41617424
65Long-term potentiation_Homo sapiens_hsa047200.40350905
66Thyroid hormone signaling pathway_Homo sapiens_hsa049190.37128361
67Renin secretion_Homo sapiens_hsa049240.37034133
68Linoleic acid metabolism_Homo sapiens_hsa005910.35952822
69Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.34530184
70Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.33726030
71Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.31906300
72Olfactory transduction_Homo sapiens_hsa047400.31301314
73Amphetamine addiction_Homo sapiens_hsa050310.30374784
74Insulin secretion_Homo sapiens_hsa049110.29617757
75Adherens junction_Homo sapiens_hsa045200.29167112
76GABAergic synapse_Homo sapiens_hsa047270.28604425
77Cysteine and methionine metabolism_Homo sapiens_hsa002700.27908952
78cAMP signaling pathway_Homo sapiens_hsa040240.27198527
79Pentose phosphate pathway_Homo sapiens_hsa000300.25683175
80Amoebiasis_Homo sapiens_hsa051460.25470821
81mTOR signaling pathway_Homo sapiens_hsa041500.25360254
82Metabolic pathways_Homo sapiens_hsa011000.25127201
83FoxO signaling pathway_Homo sapiens_hsa040680.24602241
84ECM-receptor interaction_Homo sapiens_hsa045120.24261892
85Long-term depression_Homo sapiens_hsa047300.22828269
86GnRH signaling pathway_Homo sapiens_hsa049120.22309183
87Purine metabolism_Homo sapiens_hsa002300.20864789
88Regulation of actin cytoskeleton_Homo sapiens_hsa048100.19865083
89Phototransduction_Homo sapiens_hsa047440.19033225
90Morphine addiction_Homo sapiens_hsa050320.18770688
91VEGF signaling pathway_Homo sapiens_hsa043700.18711063
92Tyrosine metabolism_Homo sapiens_hsa003500.17572293
93Bile secretion_Homo sapiens_hsa049760.17423253
94Platelet activation_Homo sapiens_hsa046110.16132844
95Leukocyte transendothelial migration_Homo sapiens_hsa046700.15776867
96Renal cell carcinoma_Homo sapiens_hsa052110.15064054
97Aldosterone synthesis and secretion_Homo sapiens_hsa049250.14870070
98Dopaminergic synapse_Homo sapiens_hsa047280.14462056
99Fat digestion and absorption_Homo sapiens_hsa049750.14259114
100Histidine metabolism_Homo sapiens_hsa003400.13872296
101Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.12253289
102Glycerolipid metabolism_Homo sapiens_hsa005610.11592380
103Dorso-ventral axis formation_Homo sapiens_hsa043200.11345001
104Glycerophospholipid metabolism_Homo sapiens_hsa005640.11305841
105Serotonergic synapse_Homo sapiens_hsa047260.11193971
106Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.10696149
107Ovarian steroidogenesis_Homo sapiens_hsa049130.10606459
108Proteoglycans in cancer_Homo sapiens_hsa052050.10151554
109ABC transporters_Homo sapiens_hsa020100.08109993
110MAPK signaling pathway_Homo sapiens_hsa040100.07608267
111Circadian entrainment_Homo sapiens_hsa047130.04883789
112Pancreatic secretion_Homo sapiens_hsa049720.02598811
113alpha-Linolenic acid metabolism_Homo sapiens_hsa00592-0.0483513
114Gap junction_Homo sapiens_hsa04540-0.0375074
115Glycine, serine and threonine metabolism_Homo sapiens_hsa00260-0.0363614
116Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961-0.0193186
117Toxoplasmosis_Homo sapiens_hsa05145-0.0081397
118AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933-0.0077385
119Cholinergic synapse_Homo sapiens_hsa04725-0.0076263

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