FBXO41

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the F-box protein family, which is characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one of the four subunits of the SCF ubiquitin protein ligase complex that plays a role in phosphorylation-dependent ubiquitination. F-box proteins are divided into three classes depending on the interaction substrate domain each contains in addition to the F-box motif: FBXW proteins contain WD-40 domains, FBXL proteins contain leucine-rich repeats, and FBXO proteins contain either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the FBXO class. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)6.49241814
2synaptic vesicle maturation (GO:0016188)6.34533315
3locomotory exploration behavior (GO:0035641)6.11408071
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)6.01210422
5vocalization behavior (GO:0071625)5.86543375
6positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.81018667
7regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.62252308
8synaptic vesicle exocytosis (GO:0016079)5.54230593
9glutamate secretion (GO:0014047)5.51091722
10regulation of glutamate receptor signaling pathway (GO:1900449)5.24878782
11synaptic vesicle docking involved in exocytosis (GO:0016081)5.19980817
12regulation of synaptic vesicle exocytosis (GO:2000300)5.14336293
13protein localization to synapse (GO:0035418)5.04767080
14L-amino acid import (GO:0043092)5.03304538
15cerebellar granule cell differentiation (GO:0021707)4.86711712
16exploration behavior (GO:0035640)4.85854366
17ionotropic glutamate receptor signaling pathway (GO:0035235)4.81855744
18layer formation in cerebral cortex (GO:0021819)4.76169195
19regulation of long-term neuronal synaptic plasticity (GO:0048169)4.74511079
20regulation of neuronal synaptic plasticity (GO:0048168)4.72609282
21neuron cell-cell adhesion (GO:0007158)4.64968033
22neurotransmitter secretion (GO:0007269)4.59440306
23regulation of synaptic vesicle transport (GO:1902803)4.57685965
24regulation of synapse structural plasticity (GO:0051823)4.57357555
25dendritic spine morphogenesis (GO:0060997)4.54787668
26amino acid import (GO:0043090)4.43342291
27neurotransmitter-gated ion channel clustering (GO:0072578)4.42175033
28neuronal action potential propagation (GO:0019227)4.39152731
29synaptic transmission, glutamatergic (GO:0035249)4.34345209
30glutamate receptor signaling pathway (GO:0007215)4.32957080
31regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.25381684
32long-term memory (GO:0007616)4.10373468
33neuron-neuron synaptic transmission (GO:0007270)4.04288326
34proline transport (GO:0015824)4.02584720
35gamma-aminobutyric acid transport (GO:0015812)4.00960522
36positive regulation of membrane potential (GO:0045838)3.99983591
37regulation of excitatory postsynaptic membrane potential (GO:0060079)3.97247020
38regulation of dendritic spine morphogenesis (GO:0061001)3.89240830
39positive regulation of synapse maturation (GO:0090129)3.88733036
40membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.82896646
41negative regulation of dendrite morphogenesis (GO:0050774)3.82523313
42regulation of postsynaptic membrane potential (GO:0060078)3.78670212
43cellular potassium ion homeostasis (GO:0030007)3.78439465
44potassium ion homeostasis (GO:0055075)3.77561724
45neuron recognition (GO:0008038)3.72779603
46regulation of synaptic plasticity (GO:0048167)3.70760918
47cytoskeletal anchoring at plasma membrane (GO:0007016)3.68888380
48neurotransmitter transport (GO:0006836)3.67626839
49activation of protein kinase A activity (GO:0034199)3.65576201
50neuromuscular process controlling balance (GO:0050885)3.64718619
51positive regulation of Rap GTPase activity (GO:0032854)3.60224592
52regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.57476503
53auditory behavior (GO:0031223)3.55466083
54potassium ion import (GO:0010107)3.55224958
55positive regulation of synaptic transmission, GABAergic (GO:0032230)3.54995388
56sodium ion export (GO:0071436)3.54488005
57regulation of neurotransmitter secretion (GO:0046928)3.54339108
58positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.53230542
59transmission of nerve impulse (GO:0019226)3.53192398
60synaptic vesicle endocytosis (GO:0048488)3.50903326
61positive regulation of neurotransmitter secretion (GO:0001956)3.47136001
62postsynaptic membrane organization (GO:0001941)3.46778557
63regulation of synaptic transmission, glutamatergic (GO:0051966)3.46404833
64axonal fasciculation (GO:0007413)3.43514916
65regulation of neurotransmitter levels (GO:0001505)3.42353475
66dendrite morphogenesis (GO:0048813)3.42300041
67G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.39234227
68regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.39157154
69positive regulation of neurotransmitter transport (GO:0051590)3.37371800
70long-term synaptic potentiation (GO:0060291)3.37179613
71regulation of vesicle fusion (GO:0031338)3.35326725
72response to auditory stimulus (GO:0010996)3.34847976
73positive regulation of dendritic spine development (GO:0060999)3.31025608
74cerebellar Purkinje cell differentiation (GO:0021702)3.30835672
75prepulse inhibition (GO:0060134)3.29707402
76G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.29317172
77cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.28911829
78dendritic spine organization (GO:0097061)3.28107491
79regulation of dendritic spine development (GO:0060998)3.28033140
80negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.28004659
81signal complex assembly (GO:0007172)3.27659524
82regulation of neurotransmitter transport (GO:0051588)3.26591298
83positive regulation of dendritic spine morphogenesis (GO:0061003)3.26576701
84regulation of voltage-gated calcium channel activity (GO:1901385)3.26513936
85gamma-aminobutyric acid signaling pathway (GO:0007214)3.26208209
86regulation of Rap GTPase activity (GO:0032317)3.22286815
87negative regulation of synaptic transmission, GABAergic (GO:0032229)3.22206335
88membrane depolarization (GO:0051899)3.22103775
89cell communication by electrical coupling (GO:0010644)3.19524291
90glycine transport (GO:0015816)3.16636252
91learning (GO:0007612)3.14717633
92membrane depolarization during action potential (GO:0086010)3.14143030
93neuromuscular process controlling posture (GO:0050884)3.14127934
94cellular sodium ion homeostasis (GO:0006883)3.13115216
95membrane hyperpolarization (GO:0060081)3.12740871
96innervation (GO:0060384)3.11813753
97axon ensheathment in central nervous system (GO:0032291)3.11633354
98central nervous system myelination (GO:0022010)3.11633354
99behavioral defense response (GO:0002209)3.10203343
100behavioral fear response (GO:0001662)3.10203343
101vesicle transport along microtubule (GO:0047496)3.10080882
102positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.08890021
103social behavior (GO:0035176)3.08142266
104intraspecies interaction between organisms (GO:0051703)3.08142266
105neuronal ion channel clustering (GO:0045161)3.07869068
106synapse assembly (GO:0007416)3.06751739
107regulation of synaptic transmission (GO:0050804)3.05838630
108regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.05221812
109regulation of ARF protein signal transduction (GO:0032012)3.04503039
110positive regulation of synaptic transmission (GO:0050806)3.03851137
111cell migration in hindbrain (GO:0021535)3.03774996
112neuromuscular process (GO:0050905)3.02417919
113positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.02088236
114regulation of exocytosis (GO:0017157)2.99894239
115regulation of synapse maturation (GO:0090128)2.99814735
116response to histamine (GO:0034776)2.98224123
117synaptic transmission (GO:0007268)2.97821894
118regulation of ARF GTPase activity (GO:0032312)2.93910219
119peptidyl-tyrosine autophosphorylation (GO:0038083)2.93888187
120cell differentiation in hindbrain (GO:0021533)2.92027384
121negative regulation of erythrocyte differentiation (GO:0045647)2.88441230
122vesicle docking involved in exocytosis (GO:0006904)2.85330016
123synaptic vesicle transport (GO:0048489)2.81388861
124establishment of synaptic vesicle localization (GO:0097480)2.81388861
125regulation of dendrite morphogenesis (GO:0048814)2.80801902
126mating behavior (GO:0007617)2.80024000
127dicarboxylic acid transport (GO:0006835)2.79154152
128positive regulation of protein dephosphorylation (GO:0035307)2.76421906
129acidic amino acid transport (GO:0015800)2.76196707
130positive regulation of dendrite development (GO:1900006)2.73554080

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.23628983
2THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse3.46229184
3GBX2_23144817_ChIP-Seq_PC3_Human3.30355060
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.16278391
5* JARID2_20064375_ChIP-Seq_MESCs_Mouse3.11548893
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.06184004
7MYC_22102868_ChIP-Seq_BL_Human2.91692576
8KDM2B_26808549_Chip-Seq_SUP-B15_Human2.91263867
9* REST_21632747_ChIP-Seq_MESCs_Mouse2.89330947
10RARB_27405468_Chip-Seq_BRAIN_Mouse2.84943048
11LXR_22292898_ChIP-Seq_THP-1_Human2.83454643
12EZH2_18974828_ChIP-Seq_MESCs_Mouse2.76646130
13RNF2_18974828_ChIP-Seq_MESCs_Mouse2.76646130
14JARID2_20075857_ChIP-Seq_MESCs_Mouse2.69938023
15DROSHA_22980978_ChIP-Seq_HELA_Human2.69817807
16SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.61980098
17VDR_21846776_ChIP-Seq_THP-1_Human2.61110287
18SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.59291592
19* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.56818305
20SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.51234339
21* EZH2_27304074_Chip-Seq_ESCs_Mouse2.49872151
22SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.45813584
23KDM2B_26808549_Chip-Seq_DND41_Human2.43282067
24* REST_18959480_ChIP-ChIP_MESCs_Mouse2.35681376
25SUZ12_27294783_Chip-Seq_ESCs_Mouse2.32182870
26* EZH2_27294783_Chip-Seq_ESCs_Mouse2.31613783
27KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.29441402
28* RNF2_27304074_Chip-Seq_ESCs_Mouse2.24245121
29TCF7_22412390_ChIP-Seq_EML_Mouse2.22098221
30IKZF1_21737484_ChIP-ChIP_HCT116_Human2.22009509
31EED_16625203_ChIP-ChIP_MESCs_Mouse2.19918210
32MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.18669765
33CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.16423840
34EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.14780266
35NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.12969213
36ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.02309621
37AR_21572438_ChIP-Seq_LNCaP_Human1.92789838
38P68_20966046_ChIP-Seq_HELA_Human1.82892782
39GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.80032521
40KDM2B_26808549_Chip-Seq_JURKAT_Human1.78638168
41SMC4_20622854_ChIP-Seq_HELA_Human1.75954440
42NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.73965557
43KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.73441452
44SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.71134574
45ERG_21242973_ChIP-ChIP_JURKAT_Human1.69966772
46CTBP2_25329375_ChIP-Seq_LNCAP_Human1.66792576
47E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.65977516
48SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.61603845
49SRY_22984422_ChIP-ChIP_TESTIS_Rat1.60705732
50ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.59789725
51CREB1_26743006_Chip-Seq_LNCaP_Human1.59333687
52RACK7_27058665_Chip-Seq_MCF-7_Human1.56226858
53CTBP1_25329375_ChIP-Seq_LNCAP_Human1.54937665
54SMAD4_21799915_ChIP-Seq_A2780_Human1.54932176
55CTCF_27219007_Chip-Seq_ERYTHROID_Human1.47566284
56TET1_21451524_ChIP-Seq_MESCs_Mouse1.45587554
57TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.43908520
58RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.42832338
59VDR_24763502_ChIP-Seq_THP-1_Human1.42546255
60ZNF274_21170338_ChIP-Seq_K562_Hela1.39746472
61TAF15_26573619_Chip-Seq_HEK293_Human1.38624577
62SA1_27219007_Chip-Seq_ERYTHROID_Human1.38598956
63RING1B_27294783_Chip-Seq_ESCs_Mouse1.37940610
64SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.31600523
65SOX2_21211035_ChIP-Seq_LN229_Gbm1.31541775
66CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.31395165
67MAF_26560356_Chip-Seq_TH2_Human1.31155788
68DNAJC2_21179169_ChIP-ChIP_NT2_Human1.30941613
69CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.30510606
70ELK3_25401928_ChIP-Seq_HUVEC_Human1.28993937
71PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.28946224
72SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.28753311
73DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.28689189
74NR3C1_23031785_ChIP-Seq_PC12_Mouse1.28328146
75OCT4_19829295_ChIP-Seq_ESCs_Human1.28030924
76UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.27960091
77MAF_26560356_Chip-Seq_TH1_Human1.27901560
78MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.25672879
79SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.25437355
80ESR2_21235772_ChIP-Seq_MCF-7_Human1.24116489
81PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.23992209
82AR_19668381_ChIP-Seq_PC3_Human1.23375307
83KDM2B_26808549_Chip-Seq_K562_Human1.22799254
84CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.22100775
85ZFP57_27257070_Chip-Seq_ESCs_Mouse1.20922374
86SMAD3_21741376_ChIP-Seq_EPCs_Human1.19955137
87RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.18923562
88WT1_25993318_ChIP-Seq_PODOCYTE_Human1.18902205
89P300_19829295_ChIP-Seq_ESCs_Human1.18506925
90RING1B_27294783_Chip-Seq_NPCs_Mouse1.18120158
91ZFP281_18757296_ChIP-ChIP_E14_Mouse1.17961879
92AR_25329375_ChIP-Seq_VCAP_Human1.17262357
93GATA1_19941827_ChIP-Seq_MEL_Mouse1.15998439
94WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.15932045
95EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.14970892
96* STAT3_23295773_ChIP-Seq_U87_Human1.14414305
97TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.13217430
98P53_22127205_ChIP-Seq_FIBROBLAST_Human1.12517652
99SMAD_19615063_ChIP-ChIP_OVARY_Human1.12366767
100STAT6_21828071_ChIP-Seq_BEAS2B_Human1.11767414
101TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.10917674
102ELF1_20517297_ChIP-Seq_JURKAT_Human1.10531232
103CBX2_27304074_Chip-Seq_ESCs_Mouse1.09944596
104BCOR_27268052_Chip-Seq_Bcells_Human1.09479624
105PU.1_20513432_ChIP-Seq_Bcells_Mouse1.08844387
106UTX_26944678_Chip-Seq_JUKART_Human1.08395085
107TOP2B_26459242_ChIP-Seq_MCF-7_Human1.08301110
108OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.07672913
109TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.06470814
110* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.06175136
111TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.05635689
112GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05568975
113RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.05428016
114NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.03539995
115TCF4_23295773_ChIP-Seq_U87_Human1.03009886
116OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.02859163
117* FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.02744310
118YAP1_20516196_ChIP-Seq_MESCs_Mouse1.01984622
119ZNF217_24962896_ChIP-Seq_MCF-7_Human1.01942616
120CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.01854162
121BMI1_23680149_ChIP-Seq_NPCS_Mouse1.01218935
122TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.01104504
123GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.00562604
124RNF2_27304074_Chip-Seq_NSC_Mouse1.00323321
125ETS1_21867929_ChIP-Seq_TH2_Mouse0.98331579
126SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.98294253
127MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98089770
128ARNT_22903824_ChIP-Seq_MCF-7_Human0.97590531
129SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.97468444
130IGF1R_20145208_ChIP-Seq_DFB_Human0.96335684
131PIAS1_25552417_ChIP-Seq_VCAP_Human0.96034692
132SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.95993562
133P300_27058665_Chip-Seq_ZR-75-30cells_Human0.95247750
134SMAD3_21741376_ChIP-Seq_ESCs_Human0.95124540
135JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.94728685
136AHR_22903824_ChIP-Seq_MCF-7_Human0.94556300
137SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93506889
138DPY_21335234_ChIP-Seq_ESCs_Mouse0.93440400
139CDX2_19796622_ChIP-Seq_MESCs_Mouse0.93267734
140SA1_27219007_Chip-Seq_Bcells_Human0.93229155
141PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.92680488
142SMAD4_21741376_ChIP-Seq_HESCs_Human0.92058390
143PRDM14_20953172_ChIP-Seq_ESCs_Human0.91887031
144TP53_16413492_ChIP-PET_HCT116_Human0.91194762
145TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.90742245
146SMAD3_21741376_ChIP-Seq_HESCs_Human0.90677248
147TET1_21490601_ChIP-Seq_MESCs_Mouse0.90545264
148AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.90131619
149RUNX2_22187159_ChIP-Seq_PCA_Human0.90015497
150NR3C1_21868756_ChIP-Seq_MCF10A_Human0.89949638
151CTCF_27219007_Chip-Seq_Bcells_Human0.89680766
152* ZFP281_27345836_Chip-Seq_ESCs_Mouse0.89637767
153VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.88230248
154POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.87653800
155TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87653800
156TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.83683480
157RXR_22108803_ChIP-Seq_LS180_Human0.79780534

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity7.13780192
2MP0003880_abnormal_central_pattern4.80378299
3MP0003635_abnormal_synaptic_transmissio4.36814505
4MP0004270_analgesia3.93063861
5MP0009745_abnormal_behavioral_response3.52483837
6MP0002063_abnormal_learning/memory/cond3.48846487
7MP0002064_seizures3.19024397
8MP0002822_catalepsy3.09873331
9MP0009046_muscle_twitch3.08744009
10MP0001968_abnormal_touch/_nociception3.02672527
11MP0005423_abnormal_somatic_nervous2.97593986
12MP0002572_abnormal_emotion/affect_behav2.85538875
13MP0002734_abnormal_mechanical_nocicepti2.74072954
14MP0001486_abnormal_startle_reflex2.57885089
15MP0002272_abnormal_nervous_system2.53838552
16MP0002735_abnormal_chemical_nociception2.27359298
17MP0001501_abnormal_sleep_pattern2.26434832
18MP0002736_abnormal_nociception_after2.24498086
19MP0001440_abnormal_grooming_behavior2.16570130
20MP0009780_abnormal_chondrocyte_physiolo2.08523356
21MP0002733_abnormal_thermal_nociception2.07305011
22MP0001970_abnormal_pain_threshold1.97912346
23MP0004858_abnormal_nervous_system1.93063536
24MP0008569_lethality_at_weaning1.92478176
25MP0002067_abnormal_sensory_capabilities1.90603304
26MP0003123_paternal_imprinting1.90395583
27MP0000778_abnormal_nervous_system1.89834750
28MP0004811_abnormal_neuron_physiology1.89135190
29MP0002184_abnormal_innervation1.85765786
30MP0003329_amyloid_beta_deposits1.84489010
31MP0002557_abnormal_social/conspecific_i1.79254876
32MP0004924_abnormal_behavior1.78229668
33MP0005386_behavior/neurological_phenoty1.78229668
34MP0002909_abnormal_adrenal_gland1.77518307
35MP0001986_abnormal_taste_sensitivity1.70768332
36MP0003879_abnormal_hair_cell1.65482501
37MP0000955_abnormal_spinal_cord1.61595195
38MP0001348_abnormal_lacrimal_gland1.57931217
39MP0005646_abnormal_pituitary_gland1.49088647
40MP0006276_abnormal_autonomic_nervous1.47804065
41MP0004885_abnormal_endolymph1.47684232
42MP0003787_abnormal_imprinting1.45729437
43MP0002066_abnormal_motor_capabilities/c1.43645467
44MP0002882_abnormal_neuron_morphology1.43070586
45MP0001984_abnormal_olfaction1.38553252
46MP0003633_abnormal_nervous_system1.34648532
47MP0001529_abnormal_vocalization1.30014987
48MP0001905_abnormal_dopamine_level1.26467244
49MP0005645_abnormal_hypothalamus_physiol1.26283816
50MP0001502_abnormal_circadian_rhythm1.17380812
51MP0000569_abnormal_digit_pigmentation1.16772439
52MP0003631_nervous_system_phenotype1.15734513
53MP0002152_abnormal_brain_morphology1.14883793
54MP0004142_abnormal_muscle_tone1.13417052
55MP0003303_peritoneal_inflammation1.08684119
56MP0001188_hyperpigmentation1.08109491
57MP0008872_abnormal_physiological_respon1.06067781
58MP0003122_maternal_imprinting0.98483862
59MP0000751_myopathy0.97998426
60MP0001346_abnormal_lacrimal_gland0.96595721
61MP0001177_atelectasis0.96291018
62MP0002069_abnormal_eating/drinking_beha0.95216367
63MP0008260_abnormal_autophagy0.91702409
64MP0002229_neurodegeneration0.91432680
65MP0003283_abnormal_digestive_organ0.91379197
66MP0008874_decreased_physiological_sensi0.91099672
67MP0003075_altered_response_to0.90773409
68MP0008961_abnormal_basal_metabolism0.90253924
69MP0004145_abnormal_muscle_electrophysio0.85735012
70MP0005076_abnormal_cell_differentiation0.85481485
71MP0003183_abnormal_peptide_metabolism0.84218382
72MP0003632_abnormal_nervous_system0.84127899
73MP0005535_abnormal_body_temperature0.83560646
74MP0004085_abnormal_heartbeat0.81434289
75MP0004742_abnormal_vestibular_system0.79919712
76MP0003634_abnormal_glial_cell0.79776936
77MP0003690_abnormal_glial_cell0.79688352
78MP0005551_abnormal_eye_electrophysiolog0.79565468
79MP0000604_amyloidosis0.79161832
80MP0005409_darkened_coat_color0.78643495
81MP0005394_taste/olfaction_phenotype0.77647041
82MP0005499_abnormal_olfactory_system0.77647041
83MP0000013_abnormal_adipose_tissue0.77525966
84MP0010386_abnormal_urinary_bladder0.77005389
85MP0002089_abnormal_postnatal_growth/wei0.74640908
86MP0000631_abnormal_neuroendocrine_gland0.74622588
87MP0009278_abnormal_bone_marrow0.74436951
88MP0001963_abnormal_hearing_physiology0.74412538
89MP0002090_abnormal_vision0.73319851
90MP0002752_abnormal_somatic_nervous0.71150758
91MP0000920_abnormal_myelination0.68860325
92MP0003763_abnormal_thymus_physiology0.68840884
93MP0004510_myositis0.68124869
94MP0002396_abnormal_hematopoietic_system0.65670090
95MP0005058_abnormal_lysosome_morphology0.65475411
96MP0005167_abnormal_blood-brain_barrier0.65265908
97MP0004381_abnormal_hair_follicle0.62712204
98MP0003861_abnormal_nervous_system0.61942177
99MP0003137_abnormal_impulse_conducting0.61726037
100MP0002083_premature_death0.61589849
101MP0004484_altered_response_of0.60773040
102MP0005310_abnormal_salivary_gland0.60713562
103MP0004130_abnormal_muscle_cell0.60255605
104MP0004233_abnormal_muscle_weight0.59781868
105MP0002873_normal_phenotype0.59217074
106MP0005623_abnormal_meninges_morphology0.59158942
107MP0004215_abnormal_myocardial_fiber0.58644330
108MP0001664_abnormal_digestion0.58026231
109MP0003436_decreased_susceptibility_to0.57983945
110MP0002169_no_abnormal_phenotype0.57947848
111MP0005187_abnormal_penis_morphology0.57330270
112MP0005166_decreased_susceptibility_to0.56802239
113MP0003956_abnormal_body_size0.56467161
114MP0001765_abnormal_ion_homeostasis0.55173220
115MP0001485_abnormal_pinna_reflex0.54656778
116MP0002837_dystrophic_cardiac_calcinosis0.54517739
117MP0001943_abnormal_respiration0.54329894
118MP0010769_abnormal_survival0.54190409
119MP0003172_abnormal_lysosome_physiology0.54007262
120MP0003705_abnormal_hypodermis_morpholog0.53012067
121MP0001731_abnormal_postnatal_growth0.52885700
122MP0005174_abnormal_tail_pigmentation0.52671477
123MP0010234_abnormal_vibrissa_follicle0.52460207
124MP0002082_postnatal_lethality0.51355318
125MP0010770_preweaning_lethality0.51355318
126MP0003045_fibrosis0.50912427
127MP0010768_mortality/aging0.50911375
128MP0009672_abnormal_birth_weight0.50763155
129MP0005000_abnormal_immune_tolerance0.49136394
130MP0002398_abnormal_bone_marrow0.48978351

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.46246812
2Myokymia (HP:0002411)7.40906606
3Focal seizures (HP:0007359)5.79339751
4Visual hallucinations (HP:0002367)5.55403074
5Epileptic encephalopathy (HP:0200134)4.80886282
6Progressive cerebellar ataxia (HP:0002073)4.38742504
7Atonic seizures (HP:0010819)4.23977632
8Febrile seizures (HP:0002373)4.22552238
9Action tremor (HP:0002345)4.01535705
10Absence seizures (HP:0002121)3.99613565
11Generalized tonic-clonic seizures (HP:0002069)3.86312894
12Supranuclear gaze palsy (HP:0000605)3.78582779
13Broad-based gait (HP:0002136)3.76256644
14Ankle clonus (HP:0011448)3.76052215
15Dialeptic seizures (HP:0011146)3.65450225
16Poor eye contact (HP:0000817)3.55848175
17Mutism (HP:0002300)3.49588321
18Impaired vibration sensation in the lower limbs (HP:0002166)3.47772100
19Gaze-evoked nystagmus (HP:0000640)3.41697063
20Depression (HP:0000716)3.33174200
21Urinary bladder sphincter dysfunction (HP:0002839)3.29316937
22Papilledema (HP:0001085)3.23747283
23Dysdiadochokinesis (HP:0002075)3.20040161
24Impaired social interactions (HP:0000735)3.18747662
25Abnormal social behavior (HP:0012433)3.18747662
26Abnormality of the lower motor neuron (HP:0002366)3.14318933
27Dysmetria (HP:0001310)3.06928311
28Anxiety (HP:0000739)3.06645904
29Amblyopia (HP:0000646)3.05014326
30Postural instability (HP:0002172)3.04018633
31Truncal ataxia (HP:0002078)3.03405615
32Hyperventilation (HP:0002883)2.97426060
33Abnormal eating behavior (HP:0100738)2.94298039
34Urinary urgency (HP:0000012)2.87406483
35Genetic anticipation (HP:0003743)2.85440464
36Tetraplegia (HP:0002445)2.85112564
37Torticollis (HP:0000473)2.84426880
38Impaired smooth pursuit (HP:0007772)2.80627731
39Cerebral hypomyelination (HP:0006808)2.79706205
40Excessive salivation (HP:0003781)2.78910633
41Drooling (HP:0002307)2.78910633
42Cerebral inclusion bodies (HP:0100314)2.70964968
43Peripheral hypomyelination (HP:0007182)2.70915551
44Spastic gait (HP:0002064)2.69514500
45Hemiparesis (HP:0001269)2.64201349
46Neurofibrillary tangles (HP:0002185)2.64186178
47Focal dystonia (HP:0004373)2.63981109
48Progressive inability to walk (HP:0002505)2.63457597
49Stereotypic behavior (HP:0000733)2.58881622
50Abnormality of binocular vision (HP:0011514)2.57766550
51Diplopia (HP:0000651)2.57766550
52Bradykinesia (HP:0002067)2.55845669
53Intention tremor (HP:0002080)2.54129899
54Slow saccadic eye movements (HP:0000514)2.51209517
55Diminished motivation (HP:0000745)2.50001611
56Megalencephaly (HP:0001355)2.48410333
57Limb dystonia (HP:0002451)2.47725052
58Epileptiform EEG discharges (HP:0011182)2.47459111
59Amyotrophic lateral sclerosis (HP:0007354)2.47079270
60Abnormality of ocular smooth pursuit (HP:0000617)2.46631724
61Abnormality of the corticospinal tract (HP:0002492)2.45812211
62Hemiplegia (HP:0002301)2.44787246
63Hyperacusis (HP:0010780)2.44192635
64Scanning speech (HP:0002168)2.41407040
65EEG with generalized epileptiform discharges (HP:0011198)2.39456151
66Turricephaly (HP:0000262)2.38793046
67Termporal pattern (HP:0011008)2.38301069
68Insidious onset (HP:0003587)2.38301069
69Insomnia (HP:0100785)2.37489692
70Craniofacial dystonia (HP:0012179)2.35320096
71Fetal akinesia sequence (HP:0001989)2.34753735
72Impaired vibratory sensation (HP:0002495)2.33975400
73Annular pancreas (HP:0001734)2.33236494
74Ventricular fibrillation (HP:0001663)2.32989920
75Hypsarrhythmia (HP:0002521)2.28832806
76Dysmetric saccades (HP:0000641)2.27311548
77Spinal canal stenosis (HP:0003416)2.26429879
78Absent speech (HP:0001344)2.26066717
79Pointed chin (HP:0000307)2.26042327
80Lower limb muscle weakness (HP:0007340)2.25638939
81Obstructive sleep apnea (HP:0002870)2.23702554
82Status epilepticus (HP:0002133)2.20091225
83Inability to walk (HP:0002540)2.13208385
84Polyphagia (HP:0002591)2.10798003
85Generalized myoclonic seizures (HP:0002123)2.10589804
86Sleep apnea (HP:0010535)2.10501531
87Agitation (HP:0000713)2.09181584
88Clonus (HP:0002169)2.06109902
89Inappropriate behavior (HP:0000719)2.05409528
90Pheochromocytoma (HP:0002666)2.05180118
91Ocular albinism (HP:0001107)2.04818603
92Lower limb amyotrophy (HP:0007210)2.01231895
93Choreoathetosis (HP:0001266)2.00803729
94Spastic tetraparesis (HP:0001285)1.98423843
95Memory impairment (HP:0002354)1.94341634
96Gait ataxia (HP:0002066)1.93914236
97Incomplete penetrance (HP:0003829)1.92518172
98Upper limb amyotrophy (HP:0009129)1.92506771
99Distal upper limb amyotrophy (HP:0007149)1.92506771
100Neuronal loss in central nervous system (HP:0002529)1.91568482
101Delusions (HP:0000746)1.90189772
102Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.89359269
103Apathy (HP:0000741)1.87735060
104Cellulitis (HP:0100658)1.87378005
105Lower limb asymmetry (HP:0100559)1.87150468
106Bundle branch block (HP:0011710)1.86299854
107Akinesia (HP:0002304)1.85812818
108Ankyloglossia (HP:0010296)1.84306406
109Deep palmar crease (HP:0006191)1.84241612
110Abnormality of salivation (HP:0100755)1.83182879
111Rigidity (HP:0002063)1.81787036
112Resting tremor (HP:0002322)1.80140503
113Abnormal EKG (HP:0003115)1.79500355
114Blue irides (HP:0000635)1.78409105
115Bowel incontinence (HP:0002607)1.78271863
116Abnormality of saccadic eye movements (HP:0000570)1.78214653
117Rapidly progressive (HP:0003678)1.77803865
118Limb ataxia (HP:0002070)1.76946660
119Thickened helices (HP:0000391)1.75092672
120Distal sensory impairment (HP:0002936)1.75065736
121Agammaglobulinemia (HP:0004432)1.74890471
122Iris hypopigmentation (HP:0007730)1.74816806
123Morphological abnormality of the pyramidal tract (HP:0002062)1.74631978
124Psychosis (HP:0000709)1.74529712
125Bronchomalacia (HP:0002780)1.74371766
126Hand muscle atrophy (HP:0009130)1.71109801
127Dementia (HP:0000726)1.70352525
128Hypercortisolism (HP:0001578)1.69742167
129Abnormality of the periventricular white matter (HP:0002518)1.64982789
130Athetosis (HP:0002305)1.64540402

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.50544941
2NTRK34.47519194
3MAP3K94.14577202
4MARK13.83119077
5MAP3K42.88761257
6DAPK22.84581506
7MINK12.79020968
8MAP2K72.35395140
9PAK62.32463811
10NTRK22.25587749
11PRKD32.16474441
12KSR22.15148153
13TRIB32.11434105
14CAMKK12.02994400
15NTRK11.87526028
16MAP2K41.79396388
17MAP3K121.73747890
18DAPK11.70421243
19RIPK41.67558575
20KSR11.64505428
21CDK51.60167215
22PRPF4B1.50077488
23SIK21.46170168
24MAPK131.43790834
25GRK51.41662496
26PLK21.39675928
27ICK1.39242932
28STK381.36649543
29CASK1.35938109
30EEF2K1.35552699
31CDK121.35345559
32TNIK1.35201131
33MAP4K11.34908258
34SMG11.29512258
35MAP3K21.25447391
36TYRO31.22511939
37PRKCG1.21032117
38TAOK11.20258514
39LATS21.19503648
40PNCK1.19058786
41ARAF1.18265571
42PHKG21.17370605
43PHKG11.17370605
44FES1.16946630
45CDK191.14900121
46SIK11.12824646
47UHMK11.07143780
48CAMKK21.05140066
49STK110.98626261
50MAP3K130.97359279
51CAMK10.93490348
52MAP3K100.92860726
53CDK180.92645931
54CDK150.92510673
55MAP3K110.91346688
56CAMK2A0.90730601
57CDK140.87655380
58RET0.85682797
59IRAK20.83988815
60ALK0.82106204
61RAF10.81050804
62CDK11A0.80679618
63PRKCH0.80236066
64SGK4940.77176015
65SGK2230.77176015
66PAK30.74815139
67ERN10.74038360
68CSNK1G20.73956415
69MARK20.73610489
70BRAF0.72819912
71CAMK2B0.71555254
72PINK10.70453283
73PTK2B0.70118635
74DYRK1A0.69612293
75SGK10.67266424
76LMTK20.64883391
77RIPK10.63604660
78TAOK20.61533358
79WNK10.61251417
80PDK10.61107341
81SGK20.61017984
82CAMK1D0.57856903
83FGFR40.57828122
84SGK30.56874759
85PDPK10.56707915
86SCYL20.56668791
87BMPR20.56479602
88PRKCZ0.56345426
89SYK0.55171199
90BLK0.53527537
91MAPK110.53052582
92OXSR10.52643022
93JAK10.51902823
94MAP3K10.49901468
95RPS6KA30.48792803
96BRSK10.48649181
97TNK20.47601218
98SIK30.47299340
99FYN0.47126661
100DAPK30.46612084
101MAP2K60.46232520
102CDC42BPA0.45801247
103HIPK20.44383421
104CAMK1G0.43654423
105PRKCE0.43264297
106CAMK40.42870987
107NME10.42724320
108NEK10.42385077
109MAPK80.41748945
110MAPK100.41718732
111PRKD20.40994683
112CCNB10.38822511
113NEK60.38102404
114MAP3K70.37759146
115PKN10.37274248
116MAP2K10.37271373
117MAP3K60.36846926
118FGR0.36680325
119CAMK2G0.36435477
120JAK20.35372253
121FGFR30.34762964
122DMPK0.34581024
123RPS6KA20.34511811
124CAMK2D0.34509864
125PKN20.34164413
126BMX0.34140878
127MAPK120.33740469
128MAP2K30.33085836
129ERBB30.31044771
130PRKCB0.30787841
131FER0.29745052

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.60540366
2Synaptic vesicle cycle_Homo sapiens_hsa047213.28767647
3Olfactory transduction_Homo sapiens_hsa047402.85090103
4Circadian entrainment_Homo sapiens_hsa047132.76846616
5Long-term potentiation_Homo sapiens_hsa047202.73811524
6GABAergic synapse_Homo sapiens_hsa047272.67537518
7Glutamatergic synapse_Homo sapiens_hsa047242.66462208
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.63843714
9Amphetamine addiction_Homo sapiens_hsa050312.49623161
10Morphine addiction_Homo sapiens_hsa050322.48718139
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.28299499
12Dopaminergic synapse_Homo sapiens_hsa047282.21672109
13Salivary secretion_Homo sapiens_hsa049702.20119860
14Insulin secretion_Homo sapiens_hsa049112.01015493
15Cholinergic synapse_Homo sapiens_hsa047251.99447584
16Gastric acid secretion_Homo sapiens_hsa049711.95340791
17Aldosterone synthesis and secretion_Homo sapiens_hsa049251.93174385
18Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.72161775
19Oxytocin signaling pathway_Homo sapiens_hsa049211.71863189
20Cocaine addiction_Homo sapiens_hsa050301.71337811
21Long-term depression_Homo sapiens_hsa047301.71295074
22Renin secretion_Homo sapiens_hsa049241.70713294
23Taste transduction_Homo sapiens_hsa047421.69587041
24Calcium signaling pathway_Homo sapiens_hsa040201.60533184
25Serotonergic synapse_Homo sapiens_hsa047261.58505806
26GnRH signaling pathway_Homo sapiens_hsa049121.52394630
27Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.45851640
28Gap junction_Homo sapiens_hsa045401.42770929
29B cell receptor signaling pathway_Homo sapiens_hsa046621.39227906
30Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.36477433
31Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.35031827
32cAMP signaling pathway_Homo sapiens_hsa040241.26976056
33Type II diabetes mellitus_Homo sapiens_hsa049301.24370459
34Estrogen signaling pathway_Homo sapiens_hsa049151.23111856
35Glioma_Homo sapiens_hsa052141.22956307
36Vitamin B6 metabolism_Homo sapiens_hsa007501.20775384
37Collecting duct acid secretion_Homo sapiens_hsa049661.20072832
38Axon guidance_Homo sapiens_hsa043601.18438981
39Phosphatidylinositol signaling system_Homo sapiens_hsa040701.17710850
40Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.11227826
41ErbB signaling pathway_Homo sapiens_hsa040121.10408216
42Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.09274601
43Melanogenesis_Homo sapiens_hsa049161.08224239
44cGMP-PKG signaling pathway_Homo sapiens_hsa040221.04694720
45Nitrogen metabolism_Homo sapiens_hsa009101.01990170
46Oocyte meiosis_Homo sapiens_hsa041140.94667580
47Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.94656362
48Vascular smooth muscle contraction_Homo sapiens_hsa042700.91970950
49Phospholipase D signaling pathway_Homo sapiens_hsa040720.91549664
50Cardiac muscle contraction_Homo sapiens_hsa042600.91421140
51Dorso-ventral axis formation_Homo sapiens_hsa043200.89241920
52Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.82166651
53Pancreatic secretion_Homo sapiens_hsa049720.81930162
54Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.80644648
55Chronic myeloid leukemia_Homo sapiens_hsa052200.79157949
56Acute myeloid leukemia_Homo sapiens_hsa052210.78015376
57Thyroid hormone synthesis_Homo sapiens_hsa049180.77781384
58Vibrio cholerae infection_Homo sapiens_hsa051100.75428574
59Choline metabolism in cancer_Homo sapiens_hsa052310.74117140
60Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.73479460
61T cell receptor signaling pathway_Homo sapiens_hsa046600.71819311
62MAPK signaling pathway_Homo sapiens_hsa040100.71466822
63Neurotrophin signaling pathway_Homo sapiens_hsa047220.70942449
64Phototransduction_Homo sapiens_hsa047440.70261239
65Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.69748295
66Dilated cardiomyopathy_Homo sapiens_hsa054140.69614987
67VEGF signaling pathway_Homo sapiens_hsa043700.69341945
68Carbohydrate digestion and absorption_Homo sapiens_hsa049730.63905789
69Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.61305804
70Central carbon metabolism in cancer_Homo sapiens_hsa052300.59762012
71Glucagon signaling pathway_Homo sapiens_hsa049220.59131067
72Rap1 signaling pathway_Homo sapiens_hsa040150.58131124
73Ras signaling pathway_Homo sapiens_hsa040140.58054057
74Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.57794162
75mTOR signaling pathway_Homo sapiens_hsa041500.56867392
76Thyroid hormone signaling pathway_Homo sapiens_hsa049190.56864617
77Sphingolipid signaling pathway_Homo sapiens_hsa040710.56814084
78Alcoholism_Homo sapiens_hsa050340.56386957
79Prolactin signaling pathway_Homo sapiens_hsa049170.55839695
80Endocytosis_Homo sapiens_hsa041440.53338818
81Endometrial cancer_Homo sapiens_hsa052130.53109539
82Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.53050476
83Bile secretion_Homo sapiens_hsa049760.51191309
84HIF-1 signaling pathway_Homo sapiens_hsa040660.49812627
85Non-small cell lung cancer_Homo sapiens_hsa052230.49733981
86Type I diabetes mellitus_Homo sapiens_hsa049400.49482977
87Osteoclast differentiation_Homo sapiens_hsa043800.48641784
88Inositol phosphate metabolism_Homo sapiens_hsa005620.48065283
89Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.47883528
90Tuberculosis_Homo sapiens_hsa051520.47344275
91Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.47134496
92Renal cell carcinoma_Homo sapiens_hsa052110.45182578
93Prion diseases_Homo sapiens_hsa050200.45082735
94Insulin signaling pathway_Homo sapiens_hsa049100.44405473
95Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.44394222
96Longevity regulating pathway - mammal_Homo sapiens_hsa042110.44085646
97Pancreatic cancer_Homo sapiens_hsa052120.43740706
98Toll-like receptor signaling pathway_Homo sapiens_hsa046200.42983157
99Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.42926015
100Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.42648482
101Wnt signaling pathway_Homo sapiens_hsa043100.40915744
102AMPK signaling pathway_Homo sapiens_hsa041520.40680854
103Notch signaling pathway_Homo sapiens_hsa043300.39960103
104Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.38522136
105Other glycan degradation_Homo sapiens_hsa005110.38465084
106Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.38281288
107Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.36764128
108Circadian rhythm_Homo sapiens_hsa047100.36425140
109Chemokine signaling pathway_Homo sapiens_hsa040620.35780104
110AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.34571099
111Ovarian steroidogenesis_Homo sapiens_hsa049130.33881189
112African trypanosomiasis_Homo sapiens_hsa051430.33605334
113Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.33085594
114Colorectal cancer_Homo sapiens_hsa052100.31196559
115Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.30930233
116Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.30861522
117Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.29814366
118SNARE interactions in vesicular transport_Homo sapiens_hsa041300.26898536
119Alzheimers disease_Homo sapiens_hsa050100.26225803
120Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.25398683

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