FCF1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of gene silencing by RNA (GO:0060966)5.53791126
2regulation of posttranscriptional gene silencing (GO:0060147)5.53791126
3regulation of gene silencing by miRNA (GO:0060964)5.53791126
4ribosomal small subunit assembly (GO:0000028)5.39509196
5maturation of SSU-rRNA (GO:0030490)5.04006658
6proteasome assembly (GO:0043248)4.98360626
7DNA deamination (GO:0045006)4.83844405
8ribosomal small subunit biogenesis (GO:0042274)4.79415148
9regulation of hippo signaling (GO:0035330)4.50570030
10ribosomal large subunit biogenesis (GO:0042273)4.46552826
11viral transcription (GO:0019083)4.38722364
12transcription elongation from RNA polymerase III promoter (GO:0006385)4.31044123
13termination of RNA polymerase III transcription (GO:0006386)4.31044123
14translational termination (GO:0006415)4.30004310
15telomere maintenance via semi-conservative replication (GO:0032201)4.11778156
16ribonucleoprotein complex biogenesis (GO:0022613)4.07487156
17negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.97840032
18DNA strand elongation involved in DNA replication (GO:0006271)3.97541552
19formation of translation preinitiation complex (GO:0001731)3.95909358
20CENP-A containing nucleosome assembly (GO:0034080)3.95854716
21kynurenine metabolic process (GO:0070189)3.90205925
22SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.87185684
237-methylguanosine mRNA capping (GO:0006370)3.86871524
24purine nucleobase biosynthetic process (GO:0009113)3.84249478
25cotranslational protein targeting to membrane (GO:0006613)3.82319039
267-methylguanosine RNA capping (GO:0009452)3.82226594
27RNA capping (GO:0036260)3.82226594
28translational elongation (GO:0006414)3.80445852
29telomere maintenance via recombination (GO:0000722)3.80259042
30DNA strand elongation (GO:0022616)3.80207504
31histone-serine phosphorylation (GO:0035404)3.78908347
32positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.77611424
33chromatin remodeling at centromere (GO:0031055)3.77501566
34protein targeting to ER (GO:0045047)3.77229029
35rRNA modification (GO:0000154)3.76475352
36regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.75301193
37DNA replication initiation (GO:0006270)3.73338964
38translational initiation (GO:0006413)3.72760660
39behavioral response to nicotine (GO:0035095)3.71769164
40anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.71344526
41nucleobase biosynthetic process (GO:0046112)3.70822789
42ribosome biogenesis (GO:0042254)3.68750517
43regulation of nuclear cell cycle DNA replication (GO:0033262)3.68092558
44* rRNA processing (GO:0006364)3.67083443
45ribosome assembly (GO:0042255)3.66674934
46DNA replication checkpoint (GO:0000076)3.66006899
47negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.62551013
48negative regulation of ligase activity (GO:0051352)3.62551013
49protein localization to endoplasmic reticulum (GO:0070972)3.62097082
50pseudouridine synthesis (GO:0001522)3.59532711
51mitotic metaphase plate congression (GO:0007080)3.59090098
52termination of RNA polymerase I transcription (GO:0006363)3.57093420
53establishment of protein localization to endoplasmic reticulum (GO:0072599)3.56968471
54transcription elongation from RNA polymerase I promoter (GO:0006362)3.56576644
55DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.55567794
56* rRNA metabolic process (GO:0016072)3.52789552
57translation (GO:0006412)3.52250031
58transcription from RNA polymerase I promoter (GO:0006360)3.52080031
59signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.51902941
60signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.51902941
61signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.51902941
62signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.50475556
63intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.50475556
64transcription-coupled nucleotide-excision repair (GO:0006283)3.48230378
65mitotic recombination (GO:0006312)3.47883303
66spliceosomal snRNP assembly (GO:0000387)3.45868311
67replicative senescence (GO:0090399)3.45591068
68nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.44672478
69regulation of cellular amino acid metabolic process (GO:0006521)3.44383235
70tryptophan catabolic process (GO:0006569)3.42936917
71indole-containing compound catabolic process (GO:0042436)3.42936917
72indolalkylamine catabolic process (GO:0046218)3.42936917
73signal transduction involved in DNA damage checkpoint (GO:0072422)3.42587575
74signal transduction involved in DNA integrity checkpoint (GO:0072401)3.42587575
75kinetochore assembly (GO:0051382)3.40718868
76cellular component biogenesis (GO:0044085)3.40035597
77kinetochore organization (GO:0051383)3.39382706
78L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.38811658
79signal transduction involved in cell cycle checkpoint (GO:0072395)3.38764205
80viral life cycle (GO:0019058)3.37613072
81cellular protein complex disassembly (GO:0043624)3.37472960
82antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.37063683
83indolalkylamine metabolic process (GO:0006586)3.33269196
84folic acid-containing compound biosynthetic process (GO:0009396)3.31800236
85telomere maintenance via telomere lengthening (GO:0010833)3.28863336
86positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.27050624
87DNA replication-independent nucleosome assembly (GO:0006336)3.26929838
88DNA replication-independent nucleosome organization (GO:0034724)3.26929838
89exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.26680516
90deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.25260136
91nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.24907034
92rRNA catabolic process (GO:0016075)3.23198507
93L-fucose catabolic process (GO:0042355)3.22122053
94fucose catabolic process (GO:0019317)3.22122053
95L-fucose metabolic process (GO:0042354)3.22122053
96viral mRNA export from host cell nucleus (GO:0046784)3.21862671
97antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.20433449
98positive regulation of ligase activity (GO:0051351)3.17643401
99DNA-dependent DNA replication (GO:0006261)3.15254414
100establishment of integrated proviral latency (GO:0075713)3.13168436
101UDP-N-acetylglucosamine metabolic process (GO:0006047)3.12570509
102maturation of 5.8S rRNA (GO:0000460)3.12296290
103G1/S transition of mitotic cell cycle (GO:0000082)3.10177036
104cell cycle G1/S phase transition (GO:0044843)3.10177036
105somatic hypermutation of immunoglobulin genes (GO:0016446)3.08333362
106somatic diversification of immune receptors via somatic mutation (GO:0002566)3.08333362
107tryptophan metabolic process (GO:0006568)3.07706829
108metaphase plate congression (GO:0051310)3.07324385
109transcription initiation from RNA polymerase I promoter (GO:0006361)3.07311044
110double-strand break repair via homologous recombination (GO:0000724)3.06826715
111histone exchange (GO:0043486)3.06544065
112epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.06350520
113recombinational repair (GO:0000725)3.05854752
114spliceosomal complex assembly (GO:0000245)3.05535202
115negative regulation by host of viral transcription (GO:0043922)3.04338676
116nucleotide-excision repair, DNA gap filling (GO:0006297)3.03508052
117lysine metabolic process (GO:0006553)3.01786658
118lysine catabolic process (GO:0006554)3.01786658
119translesion synthesis (GO:0019985)2.99659950
120regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.98646906
121tRNA modification (GO:0006400)2.98190047
122transcription elongation from RNA polymerase II promoter (GO:0006368)2.96804909
123DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.95486460
124kidney morphogenesis (GO:0060993)2.95247061
125establishment of protein localization to mitochondrial membrane (GO:0090151)2.94657229
126mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.92968793
127negative regulation of DNA repair (GO:0045738)2.92485983
128peptidyl-histidine modification (GO:0018202)2.90906371
129regulation of ubiquitin-protein transferase activity (GO:0051438)2.89680957
130negative regulation of translation, ncRNA-mediated (GO:0040033)2.89472803
131regulation of translation, ncRNA-mediated (GO:0045974)2.89472803
132negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.89472803
133protein complex disassembly (GO:0043241)2.89434402
134regulation of mitochondrial translation (GO:0070129)2.89172715
135rRNA methylation (GO:0031167)2.87295124
136nuclear-transcribed mRNA catabolic process (GO:0000956)2.86682944
137replication fork processing (GO:0031297)2.83808063
138regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.83453943
139regulation of mitotic spindle checkpoint (GO:1903504)2.83453943
140meiotic chromosome segregation (GO:0045132)2.82426626
141centriole replication (GO:0007099)2.81411085
142signal peptide processing (GO:0006465)2.81120491
143telomere maintenance via telomerase (GO:0007004)2.79858947
144negative regulation of telomere maintenance (GO:0032205)2.79540892
145tRNA processing (GO:0008033)2.75074134
146cilium or flagellum-dependent cell motility (GO:0001539)2.74278047
147regulation of centrosome cycle (GO:0046605)2.71244662
148ncRNA catabolic process (GO:0034661)2.71133954
149cellular ketone body metabolic process (GO:0046950)2.69911646
150DNA replication-dependent nucleosome organization (GO:0034723)2.68889581
151DNA replication-dependent nucleosome assembly (GO:0006335)2.68889581
152mitochondrial RNA metabolic process (GO:0000959)2.68508693
153snRNA transcription (GO:0009301)2.66763134
154regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.66685810
155regulation of centriole replication (GO:0046599)2.66512208
156negative regulation of DNA-dependent DNA replication (GO:2000104)2.66058827
157reciprocal meiotic recombination (GO:0007131)2.65955518
158reciprocal DNA recombination (GO:0035825)2.65955518
159DNA strand renaturation (GO:0000733)2.61908381
160regulation of translational termination (GO:0006449)2.58131690
161tRNA methylation (GO:0030488)2.57874813
162somatic diversification of immunoglobulins (GO:0016445)2.57044198
163regulation of mesoderm development (GO:2000380)2.56920958
164postreplication repair (GO:0006301)2.56900767
165protein K6-linked ubiquitination (GO:0085020)2.56752055
166nucleotide-excision repair, DNA damage removal (GO:0000718)2.56454170
167DNA excision (GO:0044349)2.56454170
168adult feeding behavior (GO:0008343)2.50330419
169gene silencing by RNA (GO:0031047)2.45877204
170positive regulation of G2/M transition of mitotic cell cycle (GO:0010971)2.45332419
171positive regulation of cell cycle G2/M phase transition (GO:1902751)2.45332419
172regulation of DNA endoreduplication (GO:0032875)2.42472893
173DNA replication (GO:0006260)2.42009651
174somatic recombination of immunoglobulin gene segments (GO:0016447)2.41648026
175regulation of centrosome duplication (GO:0010824)2.41510205
176protein localization to kinetochore (GO:0034501)2.41340187
177* ncRNA processing (GO:0034470)2.39053965
178tRNA metabolic process (GO:0006399)2.38705170

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.29529369
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.39671184
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.28549594
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.96204391
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.93854173
6* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.67219188
7ZNF274_21170338_ChIP-Seq_K562_Hela3.53205588
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.39265584
9* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.36321129
10SALL1_21062744_ChIP-ChIP_HESCs_Human3.23546255
11CREB1_15753290_ChIP-ChIP_HEK293T_Human3.20242847
12SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.19028764
13E2F4_17652178_ChIP-ChIP_JURKAT_Human3.18143727
14E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.03982328
15MYC_18358816_ChIP-ChIP_MESCs_Mouse2.98910386
16NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.92033988
17MYC_19079543_ChIP-ChIP_MESCs_Mouse2.89164846
18MYC_19030024_ChIP-ChIP_MESCs_Mouse2.86259003
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.84251597
20FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.80314626
21ELF1_17652178_ChIP-ChIP_JURKAT_Human2.79996194
22VDR_23849224_ChIP-Seq_CD4+_Human2.70827881
23HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.66512250
24* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.65283318
25FOXM1_23109430_ChIP-Seq_U2OS_Human2.59916072
26VDR_22108803_ChIP-Seq_LS180_Human2.49059448
27CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.46201983
28EWS_26573619_Chip-Seq_HEK293_Human2.43885854
29XRN2_22483619_ChIP-Seq_HELA_Human2.28389293
30NELFA_20434984_ChIP-Seq_ESCs_Mouse2.25863241
31DCP1A_22483619_ChIP-Seq_HELA_Human2.25306536
32E2F1_18555785_ChIP-Seq_MESCs_Mouse2.23662956
33ELK1_19687146_ChIP-ChIP_HELA_Human2.21868998
34FOXP3_21729870_ChIP-Seq_TREG_Human2.18893592
35* SRF_21415370_ChIP-Seq_HL-1_Mouse2.11730765
36SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.99748639
37GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.96008925
38FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.95757836
39MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.93794130
40TTF2_22483619_ChIP-Seq_HELA_Human1.90811471
41THAP11_20581084_ChIP-Seq_MESCs_Mouse1.89176697
42GABP_19822575_ChIP-Seq_HepG2_Human1.88928425
43YY1_21170310_ChIP-Seq_MESCs_Mouse1.86529225
44FUS_26573619_Chip-Seq_HEK293_Human1.79792819
45MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.78265449
46HOXB4_20404135_ChIP-ChIP_EML_Mouse1.78003162
47PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.76191743
48MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.74241963
49ER_23166858_ChIP-Seq_MCF-7_Human1.71120939
50AR_21909140_ChIP-Seq_LNCAP_Human1.70918492
51FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.69407718
52FLI1_27457419_Chip-Seq_LIVER_Mouse1.68351124
53EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.66851529
54POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.66189437
55NANOG_18555785_ChIP-Seq_MESCs_Mouse1.65480553
56MYCN_18555785_ChIP-Seq_MESCs_Mouse1.64956304
57PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.64677892
58* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.59403737
59ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.56277396
60YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.54680672
61TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.53384936
62RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.50564299
63E2F1_21310950_ChIP-Seq_MCF-7_Human1.48261748
64IGF1R_20145208_ChIP-Seq_DFB_Human1.45328285
65SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.44033265
66PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.41003229
67* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.40903176
68GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.38762055
69NOTCH1_21737748_ChIP-Seq_TLL_Human1.33862093
70POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.32375813
71HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.31037652
72* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.30326188
73PADI4_21655091_ChIP-ChIP_MCF-7_Human1.29977734
74SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.29845058
75IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.29440770
76* ELK1_22589737_ChIP-Seq_MCF10A_Human1.28760608
77PCGF2_27294783_Chip-Seq_ESCs_Mouse1.26519697
78CTBP1_25329375_ChIP-Seq_LNCAP_Human1.23400040
79TP53_22573176_ChIP-Seq_HFKS_Human1.23355138
80CTBP2_25329375_ChIP-Seq_LNCAP_Human1.22694672
81POU3F2_20337985_ChIP-ChIP_501MEL_Human1.21760754
82KDM5A_27292631_Chip-Seq_BREAST_Human1.20134620
83ZFX_18555785_ChIP-Seq_MESCs_Mouse1.19484800
84HOXB7_26014856_ChIP-Seq_BT474_Human1.18603349
85CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.17883542
86SPI1_23547873_ChIP-Seq_NB4_Human1.15346011
87MYC_18940864_ChIP-ChIP_HL60_Human1.12886970
88TDRD3_21172665_ChIP-Seq_MCF-7_Human1.11944115
89ZFP57_27257070_Chip-Seq_ESCs_Mouse1.11090315
90CIITA_25753668_ChIP-Seq_RAJI_Human1.10376152
91* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.06220443
92ELF5_23300383_ChIP-Seq_T47D_Human1.06135806
93IRF1_19129219_ChIP-ChIP_H3396_Human1.04695422
94IRF8_21731497_ChIP-ChIP_J774_Mouse1.03286842
95* FOXA1_27270436_Chip-Seq_PROSTATE_Human1.03193093
96* FOXA1_25329375_ChIP-Seq_VCAP_Human1.03193093
97BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.01362345
98MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.00556635
99AR_20517297_ChIP-Seq_VCAP_Human0.99352246
100P300_19829295_ChIP-Seq_ESCs_Human0.98892828
101KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.98696924
102GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.95824700
103STAT3_23295773_ChIP-Seq_U87_Human0.95442707
104E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.95214956
105SOX2_18555785_ChIP-Seq_MESCs_Mouse0.93870381
106CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.91735932
107ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.91174509
108CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.90631354
109TFEB_21752829_ChIP-Seq_HELA_Human0.89753124
110NANOG_16153702_ChIP-ChIP_HESCs_Human0.88877625
111STAT3_1855785_ChIP-Seq_MESCs_Mouse0.88025992
112TP63_19390658_ChIP-ChIP_HaCaT_Human0.86684030
113GBX2_23144817_ChIP-Seq_PC3_Human0.86085794
114PCGF2_27294783_Chip-Seq_NPCs_Mouse0.85872310
115SOX17_20123909_ChIP-Seq_XEN_Mouse0.85263647
116CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.85173032
117GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.85042138
118TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.84618778
119POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.83646538
120CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.83367696
121BP1_19119308_ChIP-ChIP_Hs578T_Human0.82589871
122* TCF4_23295773_ChIP-Seq_U87_Human0.81188391
123FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.79958209
124TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.79666758
125POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.79666758
126NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.79367288
127SOX2_16153702_ChIP-ChIP_HESCs_Human0.79098513
128CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.78223276
129FOXM1_26456572_ChIP-Seq_MCF-7_Human0.77937481
130KLF4_18555785_ChIP-Seq_MESCs_Mouse0.77531331
131SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.75662336
132SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.75041332
133STAT4_19710469_ChIP-ChIP_TH1__Mouse0.75004685
134SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.74424355
135LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.73809612
136SOX2_18692474_ChIP-Seq_MEFs_Mouse0.72933402
137NCOR_22424771_ChIP-Seq_293T_Human0.72682364
138TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.72597127
139IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.71591112
140CBP_20019798_ChIP-Seq_JUKART_Human0.71591112
141GATA3_26560356_Chip-Seq_TH2_Human0.71372311
142HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.71196041
143AHR_22903824_ChIP-Seq_MCF-7_Human0.70763392
144HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.70745739
145IRF8_22096565_ChIP-ChIP_GC-B_Human0.70519503
146KAP1_22055183_ChIP-Seq_ESCs_Mouse0.69794783
147OCT4_18692474_ChIP-Seq_MEFs_Mouse0.67850460

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.41831816
2MP0010094_abnormal_chromosome_stability4.02181325
3MP0004957_abnormal_blastocyst_morpholog3.99447453
4MP0008057_abnormal_DNA_replication3.87094364
5MP0003111_abnormal_nucleus_morphology3.72057157
6MP0008058_abnormal_DNA_repair3.55400221
7MP0003077_abnormal_cell_cycle3.46357289
8MP0000569_abnormal_digit_pigmentation2.89191274
9MP0003718_maternal_effect2.72035375
10MP0009379_abnormal_foot_pigmentation2.71235278
11MP0008932_abnormal_embryonic_tissue2.53445544
12MP0008007_abnormal_cellular_replicative2.52776358
13MP0003786_premature_aging2.48654771
14MP0002396_abnormal_hematopoietic_system2.44275900
15MP0003890_abnormal_embryonic-extraembry2.41381785
16MP0000383_abnormal_hair_follicle2.30022266
17MP0009053_abnormal_anal_canal2.20573299
18MP0002254_reproductive_system_inflammat2.19267895
19MP0004043_abnormal_pH_regulation2.17877460
20MP0003937_abnormal_limbs/digits/tail_de2.11521998
21MP0003186_abnormal_redox_activity2.10949578
22MP0000427_abnormal_hair_cycle2.03004436
23MP0008961_abnormal_basal_metabolism2.02707071
24MP0002653_abnormal_ependyma_morphology1.92033670
25MP0009333_abnormal_splenocyte_physiolog1.91364670
26MP0008877_abnormal_DNA_methylation1.86909131
27MP0003806_abnormal_nucleotide_metabolis1.78808064
28MP0001835_abnormal_antigen_presentation1.76579956
29MP0008875_abnormal_xenobiotic_pharmacok1.73953108
30MP0003136_yellow_coat_color1.71868350
31MP0003950_abnormal_plasma_membrane1.69376483
32MP0000490_abnormal_crypts_of1.65284846
33MP0003283_abnormal_digestive_organ1.64742358
34MP0010030_abnormal_orbit_morphology1.56297981
35MP0003195_calcinosis1.54635174
36MP0006292_abnormal_olfactory_placode1.54379725
37MP0005671_abnormal_response_to1.54373040
38MP0002132_abnormal_respiratory_system1.52464933
39MP0002148_abnormal_hypersensitivity_rea1.51457731
40MP0004147_increased_porphyrin_level1.50188624
41MP0001545_abnormal_hematopoietic_system1.49292575
42MP0005397_hematopoietic_system_phenotyp1.49292575
43MP0003646_muscle_fatigue1.48923479
44MP0001730_embryonic_growth_arrest1.47591400
45MP0006072_abnormal_retinal_apoptosis1.46824949
46MP0010678_abnormal_skin_adnexa1.46364278
47MP0009785_altered_susceptibility_to1.46080311
48MP0000350_abnormal_cell_proliferation1.45422790
49MP0003123_paternal_imprinting1.37809453
50MP0008260_abnormal_autophagy1.37512928
51MP0002084_abnormal_developmental_patter1.37401521
52MP0001348_abnormal_lacrimal_gland1.37339001
53MP0003763_abnormal_thymus_physiology1.34973362
54MP0001873_stomach_inflammation1.33146881
55MP0001286_abnormal_eye_development1.31307870
56MP0005408_hypopigmentation1.30917445
57MP0002234_abnormal_pharynx_morphology1.30343729
58MP0002111_abnormal_tail_morphology1.28979976
59MP0000313_abnormal_cell_death1.28565515
60MP0000428_abnormal_craniofacial_morphol1.27607651
61MP0000372_irregular_coat_pigmentation1.27464674
62MP0005075_abnormal_melanosome_morpholog1.27007471
63MP0001853_heart_inflammation1.26482237
64MP0002085_abnormal_embryonic_tissue1.21852835
65MP0002398_abnormal_bone_marrow1.20477642
66MP0004197_abnormal_fetal_growth/weight/1.18239361
67MP0002019_abnormal_tumor_incidence1.17170824
68MP0008872_abnormal_physiological_respon1.15446219
69MP0000689_abnormal_spleen_morphology1.14523996
70MP0005551_abnormal_eye_electrophysiolog1.14078650
71MP0003941_abnormal_skin_development1.13260483
72MP0002722_abnormal_immune_system1.12722649
73MP0002210_abnormal_sex_determination1.12199986
74MP0002697_abnormal_eye_size1.11849286
75MP0002938_white_spotting1.11491787
76MP0002102_abnormal_ear_morphology1.11300989
77MP0003011_delayed_dark_adaptation1.11023190
78MP0003119_abnormal_digestive_system1.10678078
79MP0003315_abnormal_perineum_morphology1.10527700
80MP0005025_abnormal_response_to1.08694520
81MP0002095_abnormal_skin_pigmentation1.07907925
82MP0005000_abnormal_immune_tolerance1.07324438
83MP0002452_abnormal_antigen_presenting1.05733291
84MP0002009_preneoplasia1.05409935
85MP0002723_abnormal_immune_serum1.05353470
86MP0001800_abnormal_humoral_immune1.05027560
87MP0002160_abnormal_reproductive_system1.03529250
88MP0002429_abnormal_blood_cell1.02899791
89MP0005389_reproductive_system_phenotype1.02490422
90MP0002420_abnormal_adaptive_immunity1.02372702
91MP0000716_abnormal_immune_system1.02019946
92MP0001819_abnormal_immune_cell1.01999227
93MP0002277_abnormal_respiratory_mucosa1.01259408
94MP0005084_abnormal_gallbladder_morpholo0.99617942
95MP0002163_abnormal_gland_morphology0.98652059
96MP0006036_abnormal_mitochondrial_physio0.98456435
97MP0000631_abnormal_neuroendocrine_gland0.98110118
98MP0003724_increased_susceptibility_to0.97524190
99MP0002877_abnormal_melanocyte_morpholog0.95903705
100MP0000566_synostosis0.94805169
101MP0004808_abnormal_hematopoietic_stem0.93735225
102MP0001697_abnormal_embryo_size0.93328367
103MP0001672_abnormal_embryogenesis/_devel0.93143366
104MP0005380_embryogenesis_phenotype0.93143366
105MP0002098_abnormal_vibrissa_morphology0.91880603
106MP0009697_abnormal_copulation0.91654484
107MP0008995_early_reproductive_senescence0.91640143
108MP0001188_hyperpigmentation0.91541163
109MP0005195_abnormal_posterior_eye0.90852445
110MP0002080_prenatal_lethality0.90304712
111MP0001145_abnormal_male_reproductive0.90299278
112MP0002751_abnormal_autonomic_nervous0.90180467
113MP0001542_abnormal_bone_strength0.89668785
114MP0001881_abnormal_mammary_gland0.89263431
115MP0002419_abnormal_innate_immunity0.88670122
116MP0000703_abnormal_thymus_morphology0.88489375
117MP0001119_abnormal_female_reproductive0.87721279
118MP0001764_abnormal_homeostasis0.87702437
119MP0005174_abnormal_tail_pigmentation0.87444003
120MP0001986_abnormal_taste_sensitivity0.86798279
121MP0004381_abnormal_hair_follicle0.85965158
122MP0000432_abnormal_head_morphology0.85756807
123MP0000049_abnormal_middle_ear0.85125758
124MP0002405_respiratory_system_inflammati0.83490058
125MP0000015_abnormal_ear_pigmentation0.83352094
126MP0000358_abnormal_cell_content/0.83015123
127MP0003436_decreased_susceptibility_to0.83006665
128MP0003936_abnormal_reproductive_system0.82715816
129MP0000653_abnormal_sex_gland0.82479695
130MP0001929_abnormal_gametogenesis0.82305030
131MP0000470_abnormal_stomach_morphology0.82215402
132MP0010307_abnormal_tumor_latency0.82014045
133MP0000685_abnormal_immune_system0.81196449
134MP0000858_altered_metastatic_potential0.79641245
135MP0005253_abnormal_eye_physiology0.79295342
136MP0001529_abnormal_vocalization0.78961719
137MP0000627_abnormal_mammary_gland0.78303264
138MP0003755_abnormal_palate_morphology0.78108193
139MP0000647_abnormal_sebaceous_gland0.77324078
140MP0003984_embryonic_growth_retardation0.77216170
141MP0001919_abnormal_reproductive_system0.77083101
142MP0006035_abnormal_mitochondrial_morpho0.76637326
143MP0003567_abnormal_fetal_cardiomyocyte0.76635518
144MP0001293_anophthalmia0.75141599
145MP0002928_abnormal_bile_duct0.75135921
146MP0005391_vision/eye_phenotype0.73324088
147MP0005395_other_phenotype0.73270845
148MP0002088_abnormal_embryonic_growth/wei0.72895021
149MP0000537_abnormal_urethra_morphology0.72781881
150MP0002837_dystrophic_cardiac_calcinosis0.72599109
151MP0002006_tumorigenesis0.71537978
152MP0002876_abnormal_thyroid_physiology0.71015340
153MP0000467_abnormal_esophagus_morphology0.70421243
154MP0000579_abnormal_nail_morphology0.69394836
155MP0004130_abnormal_muscle_cell0.69350222
156MP0005083_abnormal_biliary_tract0.69208037
157MP0003656_abnormal_erythrocyte_physiolo0.67764335
158MP0004133_heterotaxia0.65981625

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)4.75432049
2Abnormal number of erythroid precursors (HP:0012131)4.57420652
3Reticulocytopenia (HP:0001896)4.52479712
4Birth length less than 3rd percentile (HP:0003561)4.43877314
5Pancreatic fibrosis (HP:0100732)4.07129630
6Abnormality of midbrain morphology (HP:0002418)4.00167865
7Molar tooth sign on MRI (HP:0002419)4.00167865
8Breast hypoplasia (HP:0003187)3.79408585
93-Methylglutaconic aciduria (HP:0003535)3.51033272
10Aplastic anemia (HP:0001915)3.47022744
11Increased hepatocellular lipid droplets (HP:0006565)3.42071920
12Congenital stationary night blindness (HP:0007642)3.40721136
13Chromsome breakage (HP:0040012)3.38625898
14Macrocytic anemia (HP:0001972)3.38548580
15Hypoplasia of the pons (HP:0012110)3.34826725
16Type II lissencephaly (HP:0007260)3.29480674
17Absent/shortened dynein arms (HP:0200106)3.27350931
18Dynein arm defect of respiratory motile cilia (HP:0012255)3.27350931
19Abnormality of the pons (HP:0007361)3.24799977
20True hermaphroditism (HP:0010459)3.22713000
21Chromosomal breakage induced by crosslinking agents (HP:0003221)3.20844784
22Rough bone trabeculation (HP:0100670)3.19453830
23Cerebral hypomyelination (HP:0006808)3.12786894
24Mitochondrial inheritance (HP:0001427)3.10709163
25Nephronophthisis (HP:0000090)3.09916673
26Oral leukoplakia (HP:0002745)3.09161934
27Pallor (HP:0000980)3.05199009
28Bilateral microphthalmos (HP:0007633)3.02096572
29Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.99476071
30Type I transferrin isoform profile (HP:0003642)2.93419054
31Exertional dyspnea (HP:0002875)2.92248528
32Lipid accumulation in hepatocytes (HP:0006561)2.91617510
33Carpal bone hypoplasia (HP:0001498)2.90666949
34Acute necrotizing encephalopathy (HP:0006965)2.89486985
35Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.85649213
36Increased CSF lactate (HP:0002490)2.85104631
37Protruding tongue (HP:0010808)2.85081940
38Hepatocellular necrosis (HP:0001404)2.82060975
39Abnormality of the renal cortex (HP:0011035)2.76746501
40Abnormality of the preputium (HP:0100587)2.71373855
41Sclerocornea (HP:0000647)2.71061814
42Renal Fanconi syndrome (HP:0001994)2.68608728
43Increased serum lactate (HP:0002151)2.66230037
44Concave nail (HP:0001598)2.65333758
45Tubular atrophy (HP:0000092)2.64727441
46Clumsiness (HP:0002312)2.64583361
47Abnormality of the renal medulla (HP:0100957)2.64520700
48Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.61104715
49Decreased activity of mitochondrial respiratory chain (HP:0008972)2.61104715
50Hepatic necrosis (HP:0002605)2.57285024
51Patellar aplasia (HP:0006443)2.57027273
52Meckel diverticulum (HP:0002245)2.52753683
53Premature graying of hair (HP:0002216)2.52448358
54Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.50206821
55Abnormality of alanine metabolism (HP:0010916)2.50206821
56Hyperalaninemia (HP:0003348)2.50206821
57Abnormal respiratory epithelium morphology (HP:0012253)2.49822266
58Abnormal respiratory motile cilium morphology (HP:0005938)2.49822266
59Cystic liver disease (HP:0006706)2.47721640
60Abnormal trabecular bone morphology (HP:0100671)2.46419528
61Chronic hepatic failure (HP:0100626)2.46291433
62Abnormal mitochondria in muscle tissue (HP:0008316)2.45213270
63Furrowed tongue (HP:0000221)2.44626819
64Aplasia/Hypoplasia of the patella (HP:0006498)2.43862069
65Abnormality of the ileum (HP:0001549)2.43273569
66Progressive inability to walk (HP:0002505)2.42666400
67Aplasia/Hypoplasia of the sacrum (HP:0008517)2.41489745
68Inability to walk (HP:0002540)2.40623084
69Cerebellar dysplasia (HP:0007033)2.40573258
70Abnormality of chromosome stability (HP:0003220)2.40159847
71Increased neuronal autofluorescent lipopigment (HP:0002074)2.39935655
72Lissencephaly (HP:0001339)2.39117678
73Pendular nystagmus (HP:0012043)2.37798941
74Degeneration of anterior horn cells (HP:0002398)2.35685345
75Abnormality of the anterior horn cell (HP:0006802)2.35685345
76Respiratory difficulties (HP:0002880)2.34982644
77Abnormality of the heme biosynthetic pathway (HP:0010472)2.34333933
78Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.31010414
79Type 2 muscle fiber atrophy (HP:0003554)2.30863107
80Pancytopenia (HP:0001876)2.30819997
81Bone marrow hypocellularity (HP:0005528)2.30238811
82Abnormality of glycolysis (HP:0004366)2.29197785
83Increased serum pyruvate (HP:0003542)2.29197785
84Absent radius (HP:0003974)2.26981949
85Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.23786012
86Absent thumb (HP:0009777)2.22908143
87Secondary amenorrhea (HP:0000869)2.21602200
88Abnormal ciliary motility (HP:0012262)2.21571995
89Microvesicular hepatic steatosis (HP:0001414)2.20868927
90Genetic anticipation (HP:0003743)2.19227063
91Sparse eyelashes (HP:0000653)2.19119751
92Cleft eyelid (HP:0000625)2.18917269
93Duplicated collecting system (HP:0000081)2.18521439
94Aplasia/Hypoplasia of the tongue (HP:0010295)2.18405041
95Partial agenesis of the corpus callosum (HP:0001338)2.17807790
96Myelodysplasia (HP:0002863)2.17768773
97Progressive macrocephaly (HP:0004481)2.17512113
98Abnormality of the carotid arteries (HP:0005344)2.16659137
99Microretrognathia (HP:0000308)2.14399407
100Acute encephalopathy (HP:0006846)2.14169777
101Muscle fiber atrophy (HP:0100295)2.13556539
102Congenital, generalized hypertrichosis (HP:0004540)2.12893967
103Chorioretinal atrophy (HP:0000533)2.12744588
104Poor head control (HP:0002421)2.11877100
105Small hand (HP:0200055)2.11479586
106Horseshoe kidney (HP:0000085)2.10106926
107Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.10048054
108Absent forearm bone (HP:0003953)2.09782468
109Aplasia involving forearm bones (HP:0009822)2.09782468
110Colon cancer (HP:0003003)2.07808735
111Cellular immunodeficiency (HP:0005374)2.07706609
112Anencephaly (HP:0002323)2.06864983
113Reduced antithrombin III activity (HP:0001976)2.06557720
114IgM deficiency (HP:0002850)2.04615575
115Trismus (HP:0000211)2.04545614
116IgG deficiency (HP:0004315)2.03906802
11711 pairs of ribs (HP:0000878)2.03430182
118Impulsivity (HP:0100710)2.03201862
119Triphalangeal thumb (HP:0001199)2.02657958
120Petechiae (HP:0000967)2.01877427
121Aplasia/Hypoplasia of the uvula (HP:0010293)2.00792276
122Medial flaring of the eyebrow (HP:0010747)1.98518853
123Increased intramyocellular lipid droplets (HP:0012240)1.97952049
124Thrombocytosis (HP:0001894)1.96729469
125CNS hypomyelination (HP:0003429)1.96721980
126Esophageal atresia (HP:0002032)1.96706407
127Small intestinal stenosis (HP:0012848)1.96401327
128Duodenal stenosis (HP:0100867)1.96401327
129Parakeratosis (HP:0001036)1.96017604
130Lymphoma (HP:0002665)1.95664829
131Abnormality of the renal collecting system (HP:0004742)1.95563324
132Stenosis of the external auditory canal (HP:0000402)1.95430674
133Abolished electroretinogram (ERG) (HP:0000550)1.94322131
134Attenuation of retinal blood vessels (HP:0007843)1.94289385
135Abnormal lung lobation (HP:0002101)1.94052131
136Abnormal protein N-linked glycosylation (HP:0012347)1.93014603
137Abnormal protein glycosylation (HP:0012346)1.93014603
138Abnormal glycosylation (HP:0012345)1.93014603
139Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.93014603
140Exercise intolerance (HP:0003546)1.92753852
141Multiple enchondromatosis (HP:0005701)1.92381256
142Abnormal spermatogenesis (HP:0008669)1.92282052
143Fair hair (HP:0002286)1.92026518
144Aplasia/Hypoplasia involving the musculature (HP:0001460)1.90925831
145Granulocytopenia (HP:0001913)1.90393886
146Large for gestational age (HP:0001520)1.88094359
147Pancreatic cysts (HP:0001737)1.86402708
148Premature ovarian failure (HP:0008209)1.85879538
149Sloping forehead (HP:0000340)1.84764962
150Homocystinuria (HP:0002156)1.82794914
151Abnormality of homocysteine metabolism (HP:0010919)1.82794914
152Keratoconus (HP:0000563)1.82565111
153Increased corneal curvature (HP:0100692)1.82565111
154Abnormal respiratory motile cilium physiology (HP:0012261)1.81990932
155Septo-optic dysplasia (HP:0100842)1.81875053
156Abnormal number of incisors (HP:0011064)1.80917343
157Ectopic kidney (HP:0000086)1.80304152
158Dandy-Walker malformation (HP:0001305)1.77228492
159Abnormal albumin level (HP:0012116)1.77219402
160Hypoalbuminemia (HP:0003073)1.77219402
161Hyperventilation (HP:0002883)1.75991501
162Anophthalmia (HP:0000528)1.70442634
163Bile duct proliferation (HP:0001408)1.69889729
164Abnormal biliary tract physiology (HP:0012439)1.69889729
165Aplasia/Hypoplasia of the tibia (HP:0005772)1.69873223
166Central scotoma (HP:0000603)1.66228876
167Preaxial hand polydactyly (HP:0001177)1.66203862
168Rib fusion (HP:0000902)1.65363786
169Congenital hepatic fibrosis (HP:0002612)1.64913687
170Postaxial foot polydactyly (HP:0001830)1.64757034
171Gastrointestinal atresia (HP:0002589)1.62372122
172Increased cerebral lipofuscin (HP:0011813)1.62002590
173Renal cortical cysts (HP:0000803)1.61925017
174Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.60543882

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.76183302
2BUB14.73947784
3VRK23.78312857
4WEE13.74278624
5EIF2AK13.65115038
6NME23.34887815
7STK163.28882733
8SRPK12.87965938
9PLK42.85146817
10TAF12.79343192
11EIF2AK32.76757564
12PBK2.40585578
13VRK12.38493163
14STK38L2.12162645
15CDC72.07771295
16MKNK12.05569514
17BRSK22.00079381
18MST42.00014103
19TSSK61.84917985
20ACVR1B1.82027832
21PIM21.75265605
22LATS11.71179107
23ZAK1.67940456
24TTK1.58276612
25PLK11.57945081
26STK31.54770879
27PLK31.48483828
28MKNK21.47099930
29NEK21.46041128
30EIF2AK21.41196474
31IRAK31.35563352
32CDK121.33038952
33AURKB1.31758762
34IRAK41.28821107
35TLK11.26229604
36TESK21.23845751
37DYRK31.19303641
38ATR1.15287405
39TXK1.13151189
40CDK71.12431001
41EEF2K1.12362898
42KDR1.05318104
43EPHA21.05313709
44NME11.05060601
45CCNB11.04433458
46CHEK21.04132671
47AURKA1.04019692
48BRSK11.03900074
49RPS6KB21.01741665
50RPS6KA41.01692899
51ADRBK10.99816029
52TAOK30.99294374
53STK40.97868896
54WNK40.97117696
55TEC0.93733366
56CHUK0.92801443
57IKBKB0.88643685
58MELK0.85531329
59PIM10.85241675
60AKT30.82151806
61INSRR0.82139626
62MAP2K60.82072976
63CDK190.80396553
64CSNK2A10.77797779
65NUAK10.75939866
66MUSK0.75900391
67LATS20.75328284
68RPS6KA50.74956092
69BRAF0.74315507
70MAP3K140.73101148
71DYRK20.72260051
72PINK10.72190766
73MAP4K20.71567696
74MAP4K10.70186494
75CSNK2A20.69828508
76ERBB40.68528536
77BLK0.68102516
78ABL20.66752537
79TGFBR10.66375660
80MAP2K20.65734315
81CDK80.65724984
82NEK60.64158172
83CHEK10.63853586
84MAP3K80.62959636
85BMPR1B0.62916885
86PASK0.61357228
87BRD40.61121213
88FLT30.60919328
89TRIB30.60872744
90SMG10.60794181
91SIK20.60752482
92YES10.59833175
93MAPK150.58928826
94MAPKAPK50.56253086
95ARAF0.52950324
96BCR0.51952549
97BMPR20.51887293
98KIT0.51796874
99NEK90.50960758
100STK100.50834670
101BTK0.49629626
102ATM0.48715337
103ALK0.48509229
104PNCK0.47588936
105LYN0.47560067
106PAK10.45793049
107CSNK1G30.45478981
108CLK10.44818929
109TNIK0.44682829
110CDK40.44325110
111CDK30.43998925
112TYK20.42867299
113PIK3CA0.42364792
114PRKAA20.42100965
115RPS6KA60.41600126
116ADRBK20.41408026
117NEK10.40564719
118GRK10.38827314
119OXSR10.37558645
120CDK20.37202409
121IRAK10.36761477
122STK240.36504364
123IKBKE0.35705826
124PRKCI0.33232086
125MET0.32185369
126LRRK20.31965974
127MAPKAPK30.31898773
128CSNK1E0.31675908
129CDK10.31641622
130GRK70.31400565
131CASK0.30936022
132JAK30.30416092
133MAP3K90.30002621
134CSNK1D0.29292278
135CSNK1A10.29217967
136SYK0.28116648
137MAP3K100.27483325
138TRPM70.26526042
139MAP2K10.26072008
140MAP3K110.25838134

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.51281463
2Proteasome_Homo sapiens_hsa030504.45947442
3RNA polymerase_Homo sapiens_hsa030204.14265458
4DNA replication_Homo sapiens_hsa030303.94992672
5Mismatch repair_Homo sapiens_hsa034303.32673564
6* Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.28700144
7Homologous recombination_Homo sapiens_hsa034402.91034736
8Spliceosome_Homo sapiens_hsa030402.84088256
9Pyrimidine metabolism_Homo sapiens_hsa002402.79092672
10Nucleotide excision repair_Homo sapiens_hsa034202.52028113
11RNA transport_Homo sapiens_hsa030132.39496498
12Base excision repair_Homo sapiens_hsa034102.36738860
13Basal transcription factors_Homo sapiens_hsa030222.13430211
14Non-homologous end-joining_Homo sapiens_hsa034502.13421265
15Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.12702523
16Caffeine metabolism_Homo sapiens_hsa002322.11925212
17Fanconi anemia pathway_Homo sapiens_hsa034601.99120711
18Oxidative phosphorylation_Homo sapiens_hsa001901.88830860
19Protein export_Homo sapiens_hsa030601.88624978
20Cell cycle_Homo sapiens_hsa041101.84310502
21RNA degradation_Homo sapiens_hsa030181.72627314
22Parkinsons disease_Homo sapiens_hsa050121.70277900
23Nitrogen metabolism_Homo sapiens_hsa009101.68328098
24Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.65813004
25Tryptophan metabolism_Homo sapiens_hsa003801.58524309
26Purine metabolism_Homo sapiens_hsa002301.57640302
27Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.56625278
28One carbon pool by folate_Homo sapiens_hsa006701.55498860
29Phototransduction_Homo sapiens_hsa047441.49378707
30Huntingtons disease_Homo sapiens_hsa050161.48563175
31Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.47903286
32Vitamin B6 metabolism_Homo sapiens_hsa007501.46107089
33p53 signaling pathway_Homo sapiens_hsa041151.26158320
34Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.21301020
35Folate biosynthesis_Homo sapiens_hsa007901.19306365
36Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.16410743
37Epstein-Barr virus infection_Homo sapiens_hsa051691.10751394
38Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.08096682
39Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.07978271
40Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.07486250
41Butanoate metabolism_Homo sapiens_hsa006501.07218048
42Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.06851927
43Histidine metabolism_Homo sapiens_hsa003400.99966272
44Basal cell carcinoma_Homo sapiens_hsa052170.98984289
45Maturity onset diabetes of the young_Homo sapiens_hsa049500.98516575
46Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.98336962
47Alzheimers disease_Homo sapiens_hsa050100.96525153
48Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.95597250
49Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.91791509
50Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.89678704
51Graft-versus-host disease_Homo sapiens_hsa053320.86198257
52Hippo signaling pathway_Homo sapiens_hsa043900.84751999
53mRNA surveillance pathway_Homo sapiens_hsa030150.84349497
54Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.83278751
55Primary immunodeficiency_Homo sapiens_hsa053400.82545202
56Glutathione metabolism_Homo sapiens_hsa004800.82402156
57Hedgehog signaling pathway_Homo sapiens_hsa043400.82000611
58Allograft rejection_Homo sapiens_hsa053300.81623454
59Herpes simplex infection_Homo sapiens_hsa051680.79048212
60Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.78503873
61Arachidonic acid metabolism_Homo sapiens_hsa005900.77692309
62Lysine degradation_Homo sapiens_hsa003100.77582817
63TGF-beta signaling pathway_Homo sapiens_hsa043500.77326290
64Antigen processing and presentation_Homo sapiens_hsa046120.72979716
65Pentose phosphate pathway_Homo sapiens_hsa000300.69687125
66Intestinal immune network for IgA production_Homo sapiens_hsa046720.68674314
67Systemic lupus erythematosus_Homo sapiens_hsa053220.66710964
68Cysteine and methionine metabolism_Homo sapiens_hsa002700.66223542
69Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.66141425
70SNARE interactions in vesicular transport_Homo sapiens_hsa041300.64817273
71Drug metabolism - other enzymes_Homo sapiens_hsa009830.64706751
72Melanoma_Homo sapiens_hsa052180.64647637
73Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.63348742
74ABC transporters_Homo sapiens_hsa020100.60659816
75Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.60620585
76Chemical carcinogenesis_Homo sapiens_hsa052040.60312669
77Sulfur relay system_Homo sapiens_hsa041220.60217571
78Regulation of autophagy_Homo sapiens_hsa041400.59738117
79Legionellosis_Homo sapiens_hsa051340.57869690
80Steroid hormone biosynthesis_Homo sapiens_hsa001400.56595486
81Autoimmune thyroid disease_Homo sapiens_hsa053200.56576913
82Asthma_Homo sapiens_hsa053100.55456777
83NF-kappa B signaling pathway_Homo sapiens_hsa040640.55415016
84Metabolic pathways_Homo sapiens_hsa011000.54499355
85Bladder cancer_Homo sapiens_hsa052190.53955795
86beta-Alanine metabolism_Homo sapiens_hsa004100.52801526
87Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.52173704
88Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.50818415
89Hematopoietic cell lineage_Homo sapiens_hsa046400.50566614
90Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.49458250
91NOD-like receptor signaling pathway_Homo sapiens_hsa046210.48709526
92Measles_Homo sapiens_hsa051620.45391239
93Linoleic acid metabolism_Homo sapiens_hsa005910.44329481
94RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.40625252
95Viral carcinogenesis_Homo sapiens_hsa052030.40373931
96Fatty acid elongation_Homo sapiens_hsa000620.39335370
97MicroRNAs in cancer_Homo sapiens_hsa052060.38208685
98Cyanoamino acid metabolism_Homo sapiens_hsa004600.37228617
99Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.36521938
100Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.36514224
101Sphingolipid metabolism_Homo sapiens_hsa006000.35649686
102Taste transduction_Homo sapiens_hsa047420.35283258
103Oocyte meiosis_Homo sapiens_hsa041140.35260252
104Sulfur metabolism_Homo sapiens_hsa009200.34033776
105Retinol metabolism_Homo sapiens_hsa008300.33943145
106Steroid biosynthesis_Homo sapiens_hsa001000.33418579
107Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.33055237
108Pentose and glucuronate interconversions_Homo sapiens_hsa000400.32028881
109Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.31968810
110Small cell lung cancer_Homo sapiens_hsa052220.31231476
111Apoptosis_Homo sapiens_hsa042100.30697161
112Fatty acid biosynthesis_Homo sapiens_hsa000610.30651164
113Ether lipid metabolism_Homo sapiens_hsa005650.30017440
114Propanoate metabolism_Homo sapiens_hsa006400.29765853
115Rheumatoid arthritis_Homo sapiens_hsa053230.28704252
116Olfactory transduction_Homo sapiens_hsa047400.28196941
117Other glycan degradation_Homo sapiens_hsa005110.27658989
118Pathways in cancer_Homo sapiens_hsa052000.27207517
119Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.27163838
120HTLV-I infection_Homo sapiens_hsa051660.25929281
121Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.25238756
122Vitamin digestion and absorption_Homo sapiens_hsa049770.25007563
123Shigellosis_Homo sapiens_hsa051310.24550895
124alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.24167690
125Arginine and proline metabolism_Homo sapiens_hsa003300.22346152
126Fructose and mannose metabolism_Homo sapiens_hsa000510.21817839
127Influenza A_Homo sapiens_hsa051640.21814147
128Type I diabetes mellitus_Homo sapiens_hsa049400.21588586
129Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.20554793
130Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.19968740
131Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.19880315
132Glycerolipid metabolism_Homo sapiens_hsa005610.19666712
133Selenocompound metabolism_Homo sapiens_hsa004500.18066021
134Malaria_Homo sapiens_hsa051440.17469786
135N-Glycan biosynthesis_Homo sapiens_hsa005100.16579698
136Transcriptional misregulation in cancer_Homo sapiens_hsa052020.15282424
137Leishmaniasis_Homo sapiens_hsa051400.14279707
138Biosynthesis of amino acids_Homo sapiens_hsa012300.11637990
139Cardiac muscle contraction_Homo sapiens_hsa042600.10346007
140Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.09878272
141Pertussis_Homo sapiens_hsa051330.09454004
142Phagosome_Homo sapiens_hsa041450.06513141
143Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.06500996
144Renin-angiotensin system_Homo sapiens_hsa046140.06269129

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