FCGBP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1intestinal absorption (GO:0050892)8.88563722
2intestinal cholesterol absorption (GO:0030299)8.74824157
3hemidesmosome assembly (GO:0031581)7.83345988
4bundle of His cell to Purkinje myocyte communication (GO:0086069)7.76050274
5angiotensin maturation (GO:0002003)7.65421591
6virion attachment to host cell (GO:0019062)7.14100246
7adhesion of symbiont to host cell (GO:0044650)7.14100246
8regulation of bile acid biosynthetic process (GO:0070857)6.99575918
9antigen processing and presentation of endogenous antigen (GO:0019883)5.73443368
10adhesion of symbiont to host (GO:0044406)5.64870795
11maintenance of gastrointestinal epithelium (GO:0030277)5.49924796
12UDP-N-acetylglucosamine metabolic process (GO:0006047)5.40554368
13regulation of guanylate cyclase activity (GO:0031282)5.21826206
14actin filament depolymerization (GO:0030042)5.12149656
15positive regulation of respiratory burst (GO:0060267)5.04919820
16desmosome organization (GO:0002934)4.84707444
17intestinal epithelial cell development (GO:0060576)4.72854825
18regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)4.70699410
19digestive system process (GO:0022600)4.49494866
20glucocorticoid biosynthetic process (GO:0006704)4.39357402
21NADH metabolic process (GO:0006734)4.38228471
22glomerular filtration (GO:0003094)4.35219175
23epithelial structure maintenance (GO:0010669)4.34644769
24vitamin A metabolic process (GO:0006776)4.30217946
25antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.29814996
26antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.29814996
27regulation of systemic arterial blood pressure by hormone (GO:0001990)4.19553830
28regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)4.19553830
29endocrine process (GO:0050886)4.19553830
30bile acid and bile salt transport (GO:0015721)4.15002685
31renal filtration (GO:0097205)3.97663759
32regulation of vitamin metabolic process (GO:0030656)3.94444742
33fat-soluble vitamin biosynthetic process (GO:0042362)3.93595811
34antibacterial humoral response (GO:0019731)3.82122426
35O-glycan processing (GO:0016266)3.81847443
36antimicrobial humoral response (GO:0019730)3.76503904
37positive regulation of pseudopodium assembly (GO:0031274)3.73946069
38hepatocyte apoptotic process (GO:0097284)3.73081737
39cellular glucuronidation (GO:0052695)3.72587812
40cellular response to hepatocyte growth factor stimulus (GO:0035729)3.71262807
41response to hepatocyte growth factor (GO:0035728)3.71262807
42regulation of systemic arterial blood pressure (GO:0003073)3.70454638
43renal system process involved in regulation of blood volume (GO:0001977)3.70328096
44receptor guanylyl cyclase signaling pathway (GO:0007168)3.69688221
45positive regulation of guanylate cyclase activity (GO:0031284)3.68115573
46epoxygenase P450 pathway (GO:0019373)3.67538696
47glycosphingolipid catabolic process (GO:0046479)3.65623331
48glucuronate metabolic process (GO:0019585)3.63148043
49uronic acid metabolic process (GO:0006063)3.63148043
50sulfate transmembrane transport (GO:1902358)3.60639765
51regulation of respiratory burst (GO:0060263)3.54536535
52oligosaccharide biosynthetic process (GO:0009312)3.53244890
53glycolipid catabolic process (GO:0019377)3.51029348
54neurotransmitter catabolic process (GO:0042135)3.49392433
55ventricular cardiac muscle cell action potential (GO:0086005)3.47042189
56urea cycle (GO:0000050)3.46116687
57complement activation, classical pathway (GO:0006958)3.38222361
58drug catabolic process (GO:0042737)3.34375619
59branching involved in labyrinthine layer morphogenesis (GO:0060670)3.31951475
60regulation of pseudopodium assembly (GO:0031272)3.31371102
61purine ribonucleoside bisphosphate metabolic process (GO:0034035)3.31155415
623-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)3.31155415
63striated muscle atrophy (GO:0014891)3.29105706
64hormone catabolic process (GO:0042447)3.27018773
65filopodium assembly (GO:0046847)3.26179555
66regulation of cGMP biosynthetic process (GO:0030826)3.25918703
67modified amino acid transport (GO:0072337)3.20387389
68urea metabolic process (GO:0019627)3.20198528
69intermediate filament organization (GO:0045109)3.19036299
70regulation of cholesterol homeostasis (GO:2000188)3.16925967
71cGMP-mediated signaling (GO:0019934)3.16722170
72lipoprotein transport (GO:0042953)3.15362788
73ethanol oxidation (GO:0006069)3.12700645
74cell communication involved in cardiac conduction (GO:0086065)3.12251693
75flavonoid metabolic process (GO:0009812)3.08960821
76negative regulation of keratinocyte proliferation (GO:0010839)3.08365274
77lipoprotein metabolic process (GO:0042157)3.07972359
78regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.05359249
79fructose metabolic process (GO:0006000)3.04986180
80regulation of cellular extravasation (GO:0002691)3.04668104
81bicarbonate transport (GO:0015701)3.02756093
82thrombin receptor signaling pathway (GO:0070493)3.02742181
83positive regulation of p38MAPK cascade (GO:1900745)3.02726808
84negative regulation of myotube differentiation (GO:0010832)3.02284427
85cellular response to vitamin D (GO:0071305)3.02017618
86thyroid hormone metabolic process (GO:0042403)3.01440785
87NIK/NF-kappaB signaling (GO:0038061)2.98892496
88skeletal muscle adaptation (GO:0043501)2.98613129
89peptide catabolic process (GO:0043171)2.97999728
90digestion (GO:0007586)2.96057434
91sulfur compound transport (GO:0072348)2.94416080
92nitrogen cycle metabolic process (GO:0071941)2.94338231
93calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.93190472
94asymmetric protein localization (GO:0008105)2.92651825
95cytoskeletal anchoring at plasma membrane (GO:0007016)2.92274011
96cellular response to vitamin (GO:0071295)2.90432324
97cholesterol homeostasis (GO:0042632)2.89653612
98sterol homeostasis (GO:0055092)2.88427271
99protein-lipid complex assembly (GO:0065005)2.88295920
100ceramide catabolic process (GO:0046514)2.87381724
101peptide hormone processing (GO:0016486)2.87365974
102plasma lipoprotein particle assembly (GO:0034377)2.85894340
103fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.84151465
104vitamin transmembrane transport (GO:0035461)2.83986037
105positive regulation of fatty acid beta-oxidation (GO:0032000)2.82853790
106eosinophil chemotaxis (GO:0048245)2.82587064
107thyroid hormone generation (GO:0006590)2.81610117
108lung secretory cell differentiation (GO:0061140)2.81468111
109glycosylceramide metabolic process (GO:0006677)2.79290337
110regulation of heart rate by cardiac conduction (GO:0086091)2.78324424
111sulfate transport (GO:0008272)2.78203454
112actin filament capping (GO:0051693)2.78069748
113muscle atrophy (GO:0014889)2.75757593
114regulation of Golgi to plasma membrane protein transport (GO:0042996)2.75192871
115negative regulation of cholesterol transport (GO:0032375)2.73725123
116negative regulation of sterol transport (GO:0032372)2.73725123
117drug metabolic process (GO:0017144)2.73704047
118positive regulation of glycoprotein biosynthetic process (GO:0010560)2.73268345
119tight junction assembly (GO:0070830)2.72449347
120auditory receptor cell differentiation (GO:0042491)2.72107860
121cardiac conduction (GO:0061337)2.71416235
122complement activation (GO:0006956)2.70655810
123phospholipid efflux (GO:0033700)2.68605478
124detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580)2.67325506
125sphingolipid catabolic process (GO:0030149)2.67126256
126positive regulation of Cdc42 GTPase activity (GO:0043089)2.66048094
127renal absorption (GO:0070293)2.65205666
128regulation of actin nucleation (GO:0051125)2.64333877
129transcytosis (GO:0045056)2.64216827
130cell-substrate junction assembly (GO:0007044)2.64055685
131cholesterol efflux (GO:0033344)2.63500680
132sodium ion homeostasis (GO:0055078)2.62929579
133glucocorticoid metabolic process (GO:0008211)2.61746333
134protein localization to endosome (GO:0036010)2.61625443
135sulfation (GO:0051923)2.60609391
136regulation of RIG-I signaling pathway (GO:0039535)2.59415573
137cholesterol transport (GO:0030301)2.59401565
138sterol transport (GO:0015918)2.59401565
139regulation of cGMP metabolic process (GO:0030823)2.58576145
140very-low-density lipoprotein particle assembly (GO:0034379)2.58498928
141renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)2.58203280
142sodium ion export (GO:0071436)2.55267947
143negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)2.53738224
144antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.53257245
145transepithelial transport (GO:0070633)2.52684310
146glucose 6-phosphate metabolic process (GO:0051156)2.52544547
147multicellular organismal water homeostasis (GO:0050891)2.52247961
148keratinocyte proliferation (GO:0043616)2.51739506
149nucleoside diphosphate biosynthetic process (GO:0009133)2.51362460
150epithelial cell-cell adhesion (GO:0090136)2.51320574
151membrane lipid catabolic process (GO:0046466)2.51163437
152regulation of extracellular matrix disassembly (GO:0010715)2.51030313
153regulation of viral release from host cell (GO:1902186)2.50603272
154ethanol metabolic process (GO:0006067)2.50344587
155negative regulation of steroid biosynthetic process (GO:0010894)2.50014211
156positive regulation of glycoprotein metabolic process (GO:1903020)2.49032267
157sexual reproduction (GO:0019953)2.48973470
158drug transport (GO:0015893)2.48919253
159diol metabolic process (GO:0034311)2.48760280
160eosinophil migration (GO:0072677)2.48381085
161sphingomyelin metabolic process (GO:0006684)2.46048892
162substrate-independent telencephalic tangential migration (GO:0021826)2.45564703
163substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.45564703
164diacylglycerol metabolic process (GO:0046339)2.45473273
165phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.45164359
166positive regulation of actin filament depolymerization (GO:0030836)2.44393606

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human8.79466973
2CDX2_20551321_ChIP-Seq_CACO-2_Human3.98526157
3SOX2_27498859_Chip-Seq_STOMACH_Mouse2.85179256
4TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.78642560
5BP1_19119308_ChIP-ChIP_Hs578T_Human2.71537307
6SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.54301034
7TRIM28_21343339_ChIP-Seq_HEK293_Human2.46638959
8SOX2_20726797_ChIP-Seq_SW620_Human2.21957751
9GATA4_25053715_ChIP-Seq_YYC3_Human2.15463306
10* GATA6_25053715_ChIP-Seq_YYC3_Human2.14016094
11ESR2_21235772_ChIP-Seq_MCF-7_Human2.09579040
12FOXO3_23340844_ChIP-Seq_DLD1_Human2.00288744
13TCF4_18268006_ChIP-ChIP_LS174T_Human1.95044201
14* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.86219226
15STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.85833168
16RUNX1_27514584_Chip-Seq_MCF-7_Human1.84302016
17NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.83754073
18TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.80608858
19IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.80572850
20ESR1_21235772_ChIP-Seq_MCF-7_Human1.79829121
21PPAR_26484153_Chip-Seq_NCI-H1993_Human1.78187049
22CDX2_19796622_ChIP-Seq_MESCs_Mouse1.76777530
23VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.76244437
24STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.75089407
25FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.75079823
26KLF5_25053715_ChIP-Seq_YYC3_Human1.65886517
27LXR_22158963_ChIP-Seq_LIVER_Mouse1.64563378
28PPARA_22158963_ChIP-Seq_LIVER_Mouse1.64424426
29CLOCK_20551151_ChIP-Seq_293T_Human1.62369681
30ZNF217_24962896_ChIP-Seq_MCF-7_Human1.62262325
31KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.59870517
32* ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.59804534
33SMAD_19615063_ChIP-ChIP_OVARY_Human1.56575433
34FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.55963164
35SOX9_24532713_ChIP-Seq_HFSC_Mouse1.53823925
36RARG_19884340_ChIP-ChIP_MEFs_Mouse1.50649114
37NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.49759674
38RACK7_27058665_Chip-Seq_MCF-7_Human1.45429631
39ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.44830488
40PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.43927511
41IRF8_21731497_ChIP-ChIP_J774_Mouse1.41234171
42RXR_22158963_ChIP-Seq_LIVER_Mouse1.40905335
43ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.39740185
44IRF8_27001747_Chip-Seq_BMDM_Mouse1.38098178
45BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.35445854
46SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.34230350
47KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.32175958
48SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.27839675
49SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.27839675
50SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.27308610
51DROSHA_22980978_ChIP-Seq_HELA_Human1.27123442
52ZNF263_19887448_ChIP-Seq_K562_Human1.25421508
53HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.25362352
54P63_26484246_Chip-Seq_KERATINOCYTES_Human1.24621462
55STAT6_21828071_ChIP-Seq_BEAS2B_Human1.22063155
56IRF8_22096565_ChIP-ChIP_GC-B_Human1.21863573
57ESR1_20079471_ChIP-ChIP_T-47D_Human1.20600113
58GATA2_19941826_ChIP-Seq_K562_Human1.20151173
59NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.19944420
60VDR_24763502_ChIP-Seq_THP-1_Human1.18881352
61* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.15300370
62TP53_16413492_ChIP-PET_HCT116_Human1.14753498
63EGR1_23403033_ChIP-Seq_LIVER_Mouse1.13143355
64BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.13072929
65NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.11293264
66ATF3_27146783_Chip-Seq_COLON_Human1.10349693
67AHR_22903824_ChIP-Seq_MCF-7_Human1.08894724
68FOXA2_19822575_ChIP-Seq_HepG2_Human1.08280288
69CTNNB1_20460455_ChIP-Seq_HCT116_Human1.07359160
70SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.05839846
71NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.05109745
72SPI1_23127762_ChIP-Seq_K562_Human1.04920551
73BCL6_27268052_Chip-Seq_Bcells_Human1.04166872
74PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.03610157
75E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.02427585
76VDR_21846776_ChIP-Seq_THP-1_Human1.02042224
77PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.01842968
78BCAT_22108803_ChIP-Seq_LS180_Human1.00793206
79SMAD3_21741376_ChIP-Seq_HESCs_Human0.99745145
80TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.99259955
81SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.98130724
82JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.97889815
83BCOR_27268052_Chip-Seq_Bcells_Human0.97882985
84CJUN_26792858_Chip-Seq_BT549_Human0.97746240
85CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.97000830
86GATA1_19941827_ChIP-Seq_MEL_Mouse0.96790062
87TP63_23658742_ChIP-Seq_EP156T_Human0.96739346
88ELK3_25401928_ChIP-Seq_HUVEC_Human0.96051878
89STAT1_20625510_ChIP-Seq_HELA_Human0.94966391
90CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.94635776
91JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.93597028
92GATA2_21666600_ChIP-Seq_HMVEC_Human0.93214418
93THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.93115150
94CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.92529512
95LXR_22292898_ChIP-Seq_THP-1_Human0.91777109
96CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.91684797
97SA1_27219007_Chip-Seq_Bcells_Human0.91406574
98STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.90612935
99FOXM1_26456572_ChIP-Seq_MCF-7_Human0.90077682
100ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.89534398
101Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.89427818
102NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.89157122
103TCF7_22412390_ChIP-Seq_EML_Mouse0.88759302
104EGR1_19032775_ChIP-ChIP_M12_Human0.88489158
105CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.86950253
106TET1_21451524_ChIP-Seq_MESCs_Mouse0.86920522
107GATA1_22025678_ChIP-Seq_K562_Human0.86522771
108VDR_24787735_ChIP-Seq_THP-1_Human0.85356928
109CTCF_27219007_Chip-Seq_Bcells_Human0.84624074
110AR_21909140_ChIP-Seq_LNCAP_Human0.84578945
111SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.84316989
112MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.84051032
113ARNT_22903824_ChIP-Seq_MCF-7_Human0.83613509
114ERG_21242973_ChIP-ChIP_JURKAT_Human0.83515327
115CREB1_26743006_Chip-Seq_LNCaP_Human0.83506876
116EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.82345017
117AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.82237523
118RXR_22108803_ChIP-Seq_LS180_Human0.81960608
119EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.81929791
120ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.81771721
121ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.81708474
122STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.79288843
123HIF1A_21447827_ChIP-Seq_MCF-7_Human0.79219954
124FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.79082781
125UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.79010999
126KDM2B_26808549_Chip-Seq_K562_Human0.78403029
127GATA1_19941826_ChIP-Seq_K562_Human0.77924067
128* FOXA1_25552417_ChIP-Seq_VCAP_Human0.77841685
129PIAS1_25552417_ChIP-Seq_VCAP_Human0.77653370
130P300_27058665_Chip-Seq_ZR-75-30cells_Human0.77256971
131WT1_25993318_ChIP-Seq_PODOCYTE_Human0.77172519
132TP63_22573176_ChIP-Seq_HFKS_Human0.76881407
133HNF4A_19822575_ChIP-Seq_HepG2_Human0.75182361
134JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.73558030
135KDM2B_26808549_Chip-Seq_SUP-B15_Human0.73448256

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002254_reproductive_system_inflammat7.98897217
2MP0005360_urolithiasis5.75229957
3MP0010234_abnormal_vibrissa_follicle4.90834169
4MP0001666_abnormal_nutrient_absorption3.85714839
5MP0004264_abnormal_extraembryonic_tissu3.64285145
6MP0001873_stomach_inflammation3.36700043
7MP0001346_abnormal_lacrimal_gland3.36578011
8MP0004043_abnormal_pH_regulation2.84242019
9MP0009379_abnormal_foot_pigmentation2.84075919
10MP0002876_abnormal_thyroid_physiology2.75699270
11MP0003866_abnormal_defecation2.56948168
12MP0005310_abnormal_salivary_gland2.55167730
13MP0003183_abnormal_peptide_metabolism2.39913689
14MP0000462_abnormal_digestive_system2.39716002
15MP0005085_abnormal_gallbladder_physiolo2.39664614
16MP0001348_abnormal_lacrimal_gland2.26634588
17MP0008004_abnormal_stomach_pH2.24123160
18MP0010352_gastrointestinal_tract_polyps2.21604861
19MP0010155_abnormal_intestine_physiology2.21532440
20MP0010678_abnormal_skin_adnexa2.18766049
21MP0003300_gastrointestinal_ulcer2.14726814
22MP0000538_abnormal_urinary_bladder2.11994741
23MP0000465_gastrointestinal_hemorrhage2.05779492
24MP0001849_ear_inflammation1.94807234
25MP0003705_abnormal_hypodermis_morpholog1.94383732
26MP0001663_abnormal_digestive_system1.93512243
27MP0005409_darkened_coat_color1.92149920
28MP0003303_peritoneal_inflammation1.87775106
29MP0003453_abnormal_keratinocyte_physiol1.86173072
30MP0005381_digestive/alimentary_phenotyp1.83249715
31MP0002796_impaired_skin_barrier1.82945750
32MP0000537_abnormal_urethra_morphology1.80966769
33MP0000516_abnormal_urinary_system1.80956328
34MP0005367_renal/urinary_system_phenotyp1.80956328
35MP0003252_abnormal_bile_duct1.71313484
36MP0000383_abnormal_hair_follicle1.65958819
37MP0003724_increased_susceptibility_to1.65950840
38MP0005058_abnormal_lysosome_morphology1.61436985
39MP0000685_abnormal_immune_system1.50986453
40MP0000477_abnormal_intestine_morphology1.47267774
41MP0000467_abnormal_esophagus_morphology1.40751721
42MP0005365_abnormal_bile_salt1.38955129
43MP0000579_abnormal_nail_morphology1.38362896
44MP0003436_decreased_susceptibility_to1.37461649
45MP0002277_abnormal_respiratory_mucosa1.34946389
46MP0003878_abnormal_ear_physiology1.34224757
47MP0005377_hearing/vestibular/ear_phenot1.34224757
48MP0005636_abnormal_mineral_homeostasis1.30698224
49MP0009785_altered_susceptibility_to1.28603637
50MP0001664_abnormal_digestion1.26778885
51MP0000613_abnormal_salivary_gland1.26335362
52MP0005025_abnormal_response_to1.24537539
53MP0000681_abnormal_thyroid_gland1.23165836
54MP0002098_abnormal_vibrissa_morphology1.22597698
55MP0004947_skin_inflammation1.21068713
56MP0010329_abnormal_lipoprotein_level1.19511119
57MP0008875_abnormal_xenobiotic_pharmacok1.18341523
58MP0000470_abnormal_stomach_morphology1.18058825
59MP0005670_abnormal_white_adipose1.16447137
60MP0002139_abnormal_hepatobiliary_system1.16149679
61MP0001216_abnormal_epidermal_layer1.14161783
62MP0001533_abnormal_skeleton_physiology1.06984514
63MP0002896_abnormal_bone_mineralization1.06128279
64MP0003879_abnormal_hair_cell1.05378031
65MP0001485_abnormal_pinna_reflex1.04990710
66MP0002998_abnormal_bone_remodeling1.04135394
67MP0006082_CNS_inflammation1.03773386
68MP0005501_abnormal_skin_physiology1.02746876
69MP0002822_catalepsy1.02692055
70MP0002060_abnormal_skin_morphology1.01472410
71MP0005165_increased_susceptibility_to0.99441892
72MP0006054_spinal_hemorrhage0.99004398
73MP0002148_abnormal_hypersensitivity_rea0.98616682
74MP0009840_abnormal_foam_cell0.98361086
75MP0004147_increased_porphyrin_level0.98161073
76MP0005451_abnormal_body_composition0.97064060
77MP0001764_abnormal_homeostasis0.96902151
78MP0001756_abnormal_urination0.96522232
79MP0009384_cardiac_valve_regurgitation0.94915861
80MP0005332_abnormal_amino_acid0.94602589
81MP0000678_abnormal_parathyroid_gland0.94574726
82MP0003045_fibrosis0.92200457
83MP0005023_abnormal_wound_healing0.91554864
84MP0001501_abnormal_sleep_pattern0.90504392
85MP0009643_abnormal_urine_homeostasis0.90394062
86MP0003868_abnormal_feces_composition0.90362519
87MP0000230_abnormal_systemic_arterial0.90218051
88MP0005448_abnormal_energy_balance0.87949084
89MP0005671_abnormal_response_to0.87622636
90MP0001835_abnormal_antigen_presentation0.87323939
91MP0001800_abnormal_humoral_immune0.86575600
92MP0004019_abnormal_vitamin_homeostasis0.86182318
93MP0002118_abnormal_lipid_homeostasis0.85130258
94MP0000490_abnormal_crypts_of0.84757285
95MP0002971_abnormal_brown_adipose0.84279701
96MP0008469_abnormal_protein_level0.83054266
97MP0001881_abnormal_mammary_gland0.82953250
98MP0002419_abnormal_innate_immunity0.82875573
99MP0009333_abnormal_splenocyte_physiolog0.81900602
100MP0000427_abnormal_hair_cycle0.79204013
101MP0000377_abnormal_hair_follicle0.78860854
102MP0005584_abnormal_enzyme/coenzyme_acti0.77520478
103MP0005076_abnormal_cell_differentiation0.77257567
104MP0000249_abnormal_blood_vessel0.76918980
105MP0002452_abnormal_antigen_presenting0.74778723
106MP0003091_abnormal_cell_migration0.73413574
107MP0005319_abnormal_enzyme/_coenzyme0.71912021
108MP0004858_abnormal_nervous_system0.71857798
109MP0005166_decreased_susceptibility_to0.70985417
110MP0005666_abnormal_adipose_tissue0.70515547
111MP0010771_integument_phenotype0.70050011
112MP0005000_abnormal_immune_tolerance0.68122928
113MP0001790_abnormal_immune_system0.66170061
114MP0005387_immune_system_phenotype0.66170061
115MP0000762_abnormal_tongue_morphology0.64580823
116MP0003566_abnormal_cell_adhesion0.64288793
117MP0001845_abnormal_inflammatory_respons0.64281731
118MP0000627_abnormal_mammary_gland0.64102876
119MP0000609_abnormal_liver_physiology0.63391154
120MP0000566_synostosis0.61939237
121MP0009053_abnormal_anal_canal0.60128513
122MP0001765_abnormal_ion_homeostasis0.60023793
123MP0003075_altered_response_to0.59704339
124MP0001851_eye_inflammation0.57745513
125MP0008872_abnormal_physiological_respon0.57091049
126MP0002166_altered_tumor_susceptibility0.56346914
127MP0002009_preneoplasia0.53584256
128MP0004782_abnormal_surfactant_physiolog0.52012537
129MP0002877_abnormal_melanocyte_morpholog0.51895611
130MP0002136_abnormal_kidney_physiology0.51380326
131MP0002138_abnormal_hepatobiliary_system0.51083736
132MP0001191_abnormal_skin_condition0.50794592
133MP0005275_abnormal_skin_tensile0.50468336
134MP0005084_abnormal_gallbladder_morpholo0.50304361
135MP0002089_abnormal_postnatal_growth/wei0.50095493
136MP0003329_amyloid_beta_deposits0.49536042
137MP0000604_amyloidosis0.48969668
138MP0004510_myositis0.48761610
139MP0003191_abnormal_cellular_cholesterol0.48639193

Predicted human phenotypes

RankGene SetZ-score
1Right ventricular cardiomyopathy (HP:0011663)7.82485358
2Ileus (HP:0002595)6.33194526
3Milia (HP:0001056)6.29698749
4Systemic lupus erythematosus (HP:0002725)5.90452419
5Decreased circulating renin level (HP:0003351)5.69749458
6Abnormality of glutamine family amino acid metabolism (HP:0010902)5.55871207
7Abnormality of proline metabolism (HP:0010907)5.11702062
8Hydroxyprolinuria (HP:0003080)5.11702062
9Onycholysis (HP:0001806)5.01240273
10Abnormality of renin-angiotensin system (HP:0000847)4.79268920
11Plantar hyperkeratosis (HP:0007556)4.74391875
12Atrophic scars (HP:0001075)4.70797382
13Metabolic alkalosis (HP:0200114)4.67399816
14Glomerulonephritis (HP:0000099)4.53195583
15Fragile nails (HP:0001808)4.43547025
16Abnormality of the gastric mucosa (HP:0004295)4.32806716
17Complement deficiency (HP:0004431)4.00230080
18Pili torti (HP:0003777)3.99468616
19Malnutrition (HP:0004395)3.94917769
20Congenital sensorineural hearing impairment (HP:0008527)3.92628659
21Acanthocytosis (HP:0001927)3.80012446
22Hypoplasia of dental enamel (HP:0006297)3.72167647
23Alkalosis (HP:0001948)3.65693428
24Chronic diarrhea (HP:0002028)3.60653411
25Abnormality of complement system (HP:0005339)3.58354868
26Woolly hair (HP:0002224)3.57455480
27Recurrent cutaneous fungal infections (HP:0011370)3.56020970
28Chronic mucocutaneous candidiasis (HP:0002728)3.56020970
29Thin bony cortex (HP:0002753)3.53774349
30Hyperaldosteronism (HP:0000859)3.51603815
31Hemorrhage of the eye (HP:0011885)3.43972922
32Increased IgE level (HP:0003212)3.30780201
33Conjugated hyperbilirubinemia (HP:0002908)3.26899016
34Abdominal distention (HP:0003270)3.26461732
35Fatigable weakness (HP:0003473)3.25031413
36Abnormality of the neuromuscular junction (HP:0003398)3.25031413
37Abnormality of small intestinal villus morphology (HP:0011472)3.23390515
38Villous atrophy (HP:0011473)3.23390515
39Hypobetalipoproteinemia (HP:0003563)3.23283359
40Fragile skin (HP:0001030)3.16467162
41Nephritis (HP:0000123)3.10649706
42Palmoplantar hyperkeratosis (HP:0000972)3.08697400
43Fat malabsorption (HP:0002630)2.99861868
44Mildly elevated creatine phosphokinase (HP:0008180)2.99731911
45Pustule (HP:0200039)2.99600847
46Palmar hyperkeratosis (HP:0010765)2.84993771
47Flat acetabular roof (HP:0003180)2.82805665
48Ureteral stenosis (HP:0000071)2.82450796
49Nail dystrophy (HP:0008404)2.80585146
50Lip pit (HP:0100267)2.76704908
51Keratoconjunctivitis (HP:0001096)2.76144829
52Rectal prolapse (HP:0002035)2.72547940
53Hyperparathyroidism (HP:0000843)2.65300822
54Ureteral obstruction (HP:0006000)2.62684445
55Esophageal atresia (HP:0002032)2.62531496
56Alopecia of scalp (HP:0002293)2.60349087
57Neonatal short-limb short stature (HP:0008921)2.56628067
58Abnormality of vitamin B metabolism (HP:0004340)2.56386313
59Palpitations (HP:0001962)2.55513887
60Abnormal hair laboratory examination (HP:0003328)2.53797857
61Amelogenesis imperfecta (HP:0000705)2.53336075
62Hypercortisolism (HP:0001578)2.52515047
63Dehydration (HP:0001944)2.52031552
64Autoimmune thrombocytopenia (HP:0001973)2.51275770
65Delayed epiphyseal ossification (HP:0002663)2.49419165
66Abnormality of potassium homeostasis (HP:0011042)2.48670131
67Hypokalemia (HP:0002900)2.47998094
68Abnormal blistering of the skin (HP:0008066)2.47741538
69Abnormality of calcium-phosphate metabolism (HP:0100530)2.46300817
70Thick nail (HP:0001805)2.46231589
71Flattened epiphyses (HP:0003071)2.44662270
72Hyperkalemia (HP:0002153)2.44333554
73Hyponatremia (HP:0002902)2.43380069
74Ventricular tachycardia (HP:0004756)2.40297288
75Aplasia cutis congenita (HP:0001057)2.35704036
76Recurrent fungal infections (HP:0002841)2.33922763
77Hyperactive renin-angiotensin system (HP:0000841)2.32957255
78Gastrointestinal dysmotility (HP:0002579)2.31388692
79Axonal loss (HP:0003447)2.30566892
80Curly hair (HP:0002212)2.30485340
81Poikilocytosis (HP:0004447)2.28001285
82Gingivitis (HP:0000230)2.27719238
83Autoimmune hemolytic anemia (HP:0001890)2.24224096
84Abnormality of vitamin metabolism (HP:0100508)2.23757855
85Enlarged epiphyses (HP:0010580)2.23621740
86Pterygium (HP:0001059)2.23199332
87Wide cranial sutures (HP:0010537)2.23058608
88Chronic otitis media (HP:0000389)2.22409346
89Micronodular cirrhosis (HP:0001413)2.20724690
90Intrahepatic cholestasis (HP:0001406)2.18293860
91Myopathic facies (HP:0002058)2.17544474
92Colitis (HP:0002583)2.16284318
93Abnormality of the nasal mucosa (HP:0000433)2.13694418
94Hypotension (HP:0002615)2.12822669
95Aplasia/Hypoplasia of the spleen (HP:0010451)2.11168162
96Eczematoid dermatitis (HP:0000976)2.11004276
97Confusion (HP:0001289)2.09376224
98Xanthomatosis (HP:0000991)2.08302869
99Pigmentary retinal degeneration (HP:0001146)2.07993163
100Adrenal overactivity (HP:0002717)2.07508610
101Visceral angiomatosis (HP:0100761)2.06869767
102Focal segmental glomerulosclerosis (HP:0000097)2.03600163
103Syncope (HP:0001279)2.03496276
104Bone pain (HP:0002653)2.03344882
105Hypophosphatemia (HP:0002148)2.02426584
106Abnormality of monocarboxylic acid metabolism (HP:0010996)2.01958103
107Cholelithiasis (HP:0001081)1.98849182
108Progressive sensorineural hearing impairment (HP:0000408)1.98809496
109Abnormality of the costochondral junction (HP:0000919)1.96856703
110Abnormal tarsal ossification (HP:0008369)1.96583465
111Premature loss of primary teeth (HP:0006323)1.96415003
112Segmental peripheral demyelination/remyelination (HP:0003481)1.94181358
113Abnormal biliary tract morphology (HP:0012440)1.92724101
114Ridged nail (HP:0001807)1.90228599
115Cerebral aneurysm (HP:0004944)1.89789222
116Nasal polyposis (HP:0100582)1.89112695
117Hoarse voice (HP:0001609)1.88638691
118Microretrognathia (HP:0000308)1.88072797
119Protuberant abdomen (HP:0001538)1.88055199
120Tongue fasciculations (HP:0001308)1.87507580
121Abnormality of the distal phalanx of the thumb (HP:0009617)1.87399047
122Ventricular fibrillation (HP:0001663)1.87254886
123Hepatitis (HP:0012115)1.84477857
124Inflammation of the large intestine (HP:0002037)1.83893563
125Hypolipoproteinemia (HP:0010981)1.83481577
126Asplenia (HP:0001746)1.83277227
127Abnormality of sodium homeostasis (HP:0010931)1.82700487
128Cupped ribs (HP:0000887)1.81250511
129Type I diabetes mellitus (HP:0100651)1.80908753
130Epidermoid cyst (HP:0200040)1.80523968
131Hyperphosphatemia (HP:0002905)1.80380793
132Abnormal gallbladder morphology (HP:0012437)1.80344397
133Increased mean platelet volume (HP:0011877)1.78375538
134Hemangiomatosis (HP:0007461)1.78301788
135Abnormality of carpal bone ossification (HP:0006257)1.77176942
136Abnormality of chloride homeostasis (HP:0011422)1.77119684
137Widely patent fontanelles and sutures (HP:0004492)1.75740300
138Esophageal varix (HP:0002040)1.75576267
139Nephrolithiasis (HP:0000787)1.74323342
140Vacuolated lymphocytes (HP:0001922)1.73332615
141Ventricular arrhythmia (HP:0004308)1.72951418
142Progressive hearing impairment (HP:0001730)1.71926420
143Biliary tract neoplasm (HP:0100574)1.71231294
144Abnormality of the vitamin B12 metabolism (HP:0004341)1.70680473
145Flat capital femoral epiphysis (HP:0003370)1.68738118
146Abnormal glucose tolerance (HP:0001952)1.68540037
147Goiter (HP:0000853)1.68530059
148Nausea (HP:0002018)1.68000847
149Spinal cord compression (HP:0002176)1.66550124
150Amyloidosis (HP:0011034)1.65847912
151Petechiae (HP:0000967)1.64130245
152Renal tubular acidosis (HP:0001947)1.64029051
153Bilateral sensorineural hearing impairment (HP:0008619)1.61441802
154Abnormality of macrophages (HP:0004311)1.61440919
155Dysostosis multiplex (HP:0000943)1.59764952
156Metaphyseal irregularity (HP:0003025)1.59539327
157Spontaneous hematomas (HP:0007420)1.58944781
158Glomerulosclerosis (HP:0000096)1.58534261
159Hyperammonemia (HP:0001987)1.57448211
160Abnormality of glycolipid metabolism (HP:0010969)1.56987439
161Abnormality of liposaccharide metabolism (HP:0010968)1.56987439
162Abnormality of glycosphingolipid metabolism (HP:0004343)1.56987439

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.18173367
2ACVR1B5.00536187
3MST44.80818361
4NME14.29376250
5LMTK23.94235061
6MST1R2.98660232
7EPHB12.77145835
8PTK62.53977682
9EPHA22.40469794
10EPHA32.30225838
11MAP3K142.27434674
12PRKG22.23648232
13AKT32.20930470
14RIPK12.20917742
15MAPK152.17661473
16MAP2K22.07095936
17STK391.96980783
18FGFR41.96382567
19MAP3K101.85493917
20ERN11.82502900
21FER1.82277891
22MAP3K21.78734580
23GRK61.75422049
24EPHB21.68316003
25PTK21.62781789
26TRIB31.56483931
27LATS11.54048971
28OXSR11.48126232
29TESK11.46979879
30PDK21.38339876
31TGFBR21.37188444
32BLK1.36386755
33MAP3K71.36228720
34TYK21.35862383
35DDR21.33555729
36PRPF4B1.32352896
37WNK41.27318910
38PIK3CA1.25083925
39STK101.22526200
40MAP4K11.21090043
41MATK1.15828798
42FGFR31.13214238
43ERBB21.10876898
44CSF1R1.07221890
45STK241.04919078
46NUAK11.04200906
47PDPK11.03002909
48SMG11.01353247
49TESK20.96656632
50TBK10.96012271
51CDC42BPA0.95144285
52MET0.95047962
53IKBKE0.89491212
54NLK0.88169759
55SCYL20.86723492
56TAOK10.85830960
57RPS6KB20.84793234
58CHUK0.84061622
59PDK10.83970303
60KSR20.83567913
61LRRK20.82760233
62MYLK0.81303617
63MAP2K10.80788675
64ITK0.79533192
65ZAP700.76153378
66JAK10.74652293
67PAK40.71336520
68PRKCI0.70448689
69MAPKAPK30.70105920
70MAP3K130.70082089
71JAK30.69178613
72PRKAA20.67333759
73DMPK0.66804749
74RIPK40.66240503
75IRAK30.64545957
76MAP3K10.64396867
77MAP3K110.63870438
78PAK20.61687064
79JAK20.61445385
80MAP3K80.60244774
81BMPR1B0.59904294
82IRAK10.58777762
83SIK10.58082537
84MAP3K30.57197237
85DYRK1B0.56650336
86BMX0.53717423
87TSSK60.52906630
88RPS6KA20.52066102
89ICK0.51387965
90DYRK30.50429178
91MAPK110.48495659
92MAPK70.46585236
93MAPKAPK20.46570751
94PAK30.45402037
95ABL20.45126160
96KIT0.44386806
97SRC0.44169189
98RET0.42531260
99MAP2K60.41489452
100PRKACG0.41393201
101NEK60.40695319
102PDGFRA0.38716538
103LYN0.38504358
104CDK90.38475732
105TGFBR10.37680603
106PDGFRB0.36834954
107MELK0.36439371
108CSK0.34702277
109LIMK10.34532393
110BTK0.34302211
111FGR0.34269743
112RPS6KC10.34086968
113RPS6KL10.34086968
114SYK0.33755935
115TNIK0.32967785
116DAPK20.32842064
117EEF2K0.32759559
118BCR0.31827353
119PRKD20.31729977
120LCK0.31497920
121PRKCA0.31423922
122CAMK2G0.30609302
123GRK70.30292994
124CDK60.30033604
125STK30.30028756
126FGFR20.28543116
127YES10.28209985
128GSK3A0.27867080
129INSRR0.27689680
130IGF1R0.27602425
131RPS6KA10.27539142
132ROCK10.27456854
133MAP3K90.27119542
134STK110.26538004
135ROCK20.25450555
136TTN0.24529260
137TYRO30.23266068
138CAMK2D0.22981513
139PRKAA10.20837911
140FYN0.20808156
141PKN20.19076896

Predicted pathways (KEGG)

RankGene SetZ-score
1Fat digestion and absorption_Homo sapiens_hsa049754.45896463
2Mineral absorption_Homo sapiens_hsa049783.74144387
3Renin-angiotensin system_Homo sapiens_hsa046143.62231540
4Butirosin and neomycin biosynthesis_Homo sapiens_hsa005243.38229275
5Caffeine metabolism_Homo sapiens_hsa002322.96102468
6Sulfur metabolism_Homo sapiens_hsa009202.89027658
7Vitamin digestion and absorption_Homo sapiens_hsa049772.78927537
8Histidine metabolism_Homo sapiens_hsa003402.38784888
9Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.34107109
10Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.32638266
11Bile secretion_Homo sapiens_hsa049762.27425514
12Protein digestion and absorption_Homo sapiens_hsa049742.21211440
13Carbohydrate digestion and absorption_Homo sapiens_hsa049732.11802779
14Staphylococcus aureus infection_Homo sapiens_hsa051501.95557818
15Galactose metabolism_Homo sapiens_hsa000521.94846813
16Cyanoamino acid metabolism_Homo sapiens_hsa004601.82655349
17Maturity onset diabetes of the young_Homo sapiens_hsa049501.76236385
18Other glycan degradation_Homo sapiens_hsa005111.67284416
19Autoimmune thyroid disease_Homo sapiens_hsa053201.61313148
20Starch and sucrose metabolism_Homo sapiens_hsa005001.60645933
21Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.58002756
22Retinol metabolism_Homo sapiens_hsa008301.38810451
23Drug metabolism - other enzymes_Homo sapiens_hsa009831.38712190
24Chemical carcinogenesis_Homo sapiens_hsa052041.33831506
25Allograft rejection_Homo sapiens_hsa053301.31168913
26Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.30429208
27Steroid hormone biosynthesis_Homo sapiens_hsa001401.28133867
28Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.25725879
29Tryptophan metabolism_Homo sapiens_hsa003801.24476880
30Graft-versus-host disease_Homo sapiens_hsa053321.15799592
31Fructose and mannose metabolism_Homo sapiens_hsa000511.15401874
32Tight junction_Homo sapiens_hsa045301.13107927
33Toxoplasmosis_Homo sapiens_hsa051451.05142355
34Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.04939449
35Arginine biosynthesis_Homo sapiens_hsa002201.02029786
36Adherens junction_Homo sapiens_hsa045200.98719858
37PPAR signaling pathway_Homo sapiens_hsa033200.97143964
38alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.96817032
39Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.94638877
40Antigen processing and presentation_Homo sapiens_hsa046120.94540490
41ABC transporters_Homo sapiens_hsa020100.94434194
42Folate biosynthesis_Homo sapiens_hsa007900.93881977
43Sphingolipid metabolism_Homo sapiens_hsa006000.93829532
44Intestinal immune network for IgA production_Homo sapiens_hsa046720.93739360
45Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.92631038
46Pancreatic secretion_Homo sapiens_hsa049720.91878748
47African trypanosomiasis_Homo sapiens_hsa051430.90117207
48Leukocyte transendothelial migration_Homo sapiens_hsa046700.88864698
49Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.86953505
50Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.86485524
51Type I diabetes mellitus_Homo sapiens_hsa049400.86185040
52Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.85333471
53Glutathione metabolism_Homo sapiens_hsa004800.82394279
54Amoebiasis_Homo sapiens_hsa051460.82034645
55Leishmaniasis_Homo sapiens_hsa051400.79604962
56Glycerolipid metabolism_Homo sapiens_hsa005610.79253072
57Linoleic acid metabolism_Homo sapiens_hsa005910.78422563
58Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.78116059
59Thyroid hormone synthesis_Homo sapiens_hsa049180.77381214
60Small cell lung cancer_Homo sapiens_hsa052220.75940720
61Primary immunodeficiency_Homo sapiens_hsa053400.75458284
62Hepatitis C_Homo sapiens_hsa051600.74599054
63Gastric acid secretion_Homo sapiens_hsa049710.72871407
64Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.72584873
65Arginine and proline metabolism_Homo sapiens_hsa003300.70928371
66Salmonella infection_Homo sapiens_hsa051320.70364074
67Nitrogen metabolism_Homo sapiens_hsa009100.66491443
68Bladder cancer_Homo sapiens_hsa052190.63653110
69Influenza A_Homo sapiens_hsa051640.63589279
70TNF signaling pathway_Homo sapiens_hsa046680.61657573
71Pentose and glucuronate interconversions_Homo sapiens_hsa000400.61656988
72NOD-like receptor signaling pathway_Homo sapiens_hsa046210.59045487
73Type II diabetes mellitus_Homo sapiens_hsa049300.58428441
74ECM-receptor interaction_Homo sapiens_hsa045120.57888212
75Legionellosis_Homo sapiens_hsa051340.57239056
762-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.56271128
77Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.56028027
78Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.53435393
79Glycerophospholipid metabolism_Homo sapiens_hsa005640.52822335
80Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.52691171
81Pertussis_Homo sapiens_hsa051330.52192919
82Salivary secretion_Homo sapiens_hsa049700.51484064
83Fatty acid degradation_Homo sapiens_hsa000710.51153367
84Phosphatidylinositol signaling system_Homo sapiens_hsa040700.50321973
85Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.49970223
86Osteoclast differentiation_Homo sapiens_hsa043800.49479095
87Arachidonic acid metabolism_Homo sapiens_hsa005900.48464677
88Viral myocarditis_Homo sapiens_hsa054160.47966738
89Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.47761367
90Complement and coagulation cascades_Homo sapiens_hsa046100.47237158
91Insulin resistance_Homo sapiens_hsa049310.46612732
92Prion diseases_Homo sapiens_hsa050200.45820125
93Lysosome_Homo sapiens_hsa041420.44295014
94RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.42127534
95Vibrio cholerae infection_Homo sapiens_hsa051100.41083113
96GnRH signaling pathway_Homo sapiens_hsa049120.40810580
97Tyrosine metabolism_Homo sapiens_hsa003500.40396988
98NF-kappa B signaling pathway_Homo sapiens_hsa040640.39696820
99Adipocytokine signaling pathway_Homo sapiens_hsa049200.38296962
100Ether lipid metabolism_Homo sapiens_hsa005650.37815276
101Prolactin signaling pathway_Homo sapiens_hsa049170.36092863
102Hematopoietic cell lineage_Homo sapiens_hsa046400.35383825
103Apoptosis_Homo sapiens_hsa042100.34891690
104Thyroid cancer_Homo sapiens_hsa052160.34568424
105Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.34493470
106Focal adhesion_Homo sapiens_hsa045100.33918286
107Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.32993595
108Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.32936528
109Tuberculosis_Homo sapiens_hsa051520.32559085
110Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.31096630
111Asthma_Homo sapiens_hsa053100.30132757
112VEGF signaling pathway_Homo sapiens_hsa043700.30028540
113Rheumatoid arthritis_Homo sapiens_hsa053230.29833376
114Renin secretion_Homo sapiens_hsa049240.29208364
115Proteoglycans in cancer_Homo sapiens_hsa052050.29136015
116Inositol phosphate metabolism_Homo sapiens_hsa005620.25871189
117Pyruvate metabolism_Homo sapiens_hsa006200.25723222
118Phagosome_Homo sapiens_hsa041450.25180928
119Aldosterone synthesis and secretion_Homo sapiens_hsa049250.23871166
120Hippo signaling pathway_Homo sapiens_hsa043900.22988805
121Phenylalanine metabolism_Homo sapiens_hsa003600.22484398
122Toll-like receptor signaling pathway_Homo sapiens_hsa046200.22475269
123AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.22379481
124Fatty acid metabolism_Homo sapiens_hsa012120.21865786
125Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.21816814
126Chemokine signaling pathway_Homo sapiens_hsa040620.21415839
127Dorso-ventral axis formation_Homo sapiens_hsa043200.20970738
128Choline metabolism in cancer_Homo sapiens_hsa052310.20301272
129Jak-STAT signaling pathway_Homo sapiens_hsa046300.19348985

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