

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation by symbiont of host defense response (GO:0052509) | 6.09351636 |
| 2 | modulation by symbiont of host defense response (GO:0052031) | 6.09351636 |
| 3 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 6.09351636 |
| 4 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 6.09351636 |
| 5 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 6.09351636 |
| 6 | modulation by symbiont of host immune response (GO:0052553) | 6.09351636 |
| 7 | neutrophil activation involved in immune response (GO:0002283) | 5.44178877 |
| 8 | macrophage activation involved in immune response (GO:0002281) | 5.43064687 |
| 9 | immunoglobulin mediated immune response (GO:0016064) | 5.39904126 |
| 10 | response to peptidoglycan (GO:0032494) | 5.25876508 |
| 11 | detection of molecule of bacterial origin (GO:0032490) | 5.15837880 |
| 12 | negative regulation of interleukin-12 production (GO:0032695) | 5.14679523 |
| 13 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.05275702 |
| 14 | detection of other organism (GO:0098543) | 4.95605462 |
| 15 | microglial cell activation (GO:0001774) | 4.92984305 |
| 16 | negative regulation of cell killing (GO:0031342) | 4.88936772 |
| 17 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.88936772 |
| 18 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.77194887 |
| 19 | detection of external biotic stimulus (GO:0098581) | 4.65377440 |
| 20 | detection of bacterium (GO:0016045) | 4.60663402 |
| 21 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 4.53953070 |
| 22 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 4.49196250 |
| 23 | regulation of hypersensitivity (GO:0002883) | 4.41605504 |
| 24 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.39653408 |
| 25 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.38411901 |
| 26 | B cell mediated immunity (GO:0019724) | 4.26953520 |
| 27 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.23736327 |
| 28 | cellular extravasation (GO:0045123) | 4.21057349 |
| 29 | response to host immune response (GO:0052572) | 4.16551570 |
| 30 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.16551570 |
| 31 | detection of biotic stimulus (GO:0009595) | 4.14742339 |
| 32 | macrophage activation (GO:0042116) | 4.10245921 |
| 33 | interferon-gamma-mediated signaling pathway (GO:0060333) | 4.08390646 |
| 34 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.08119291 |
| 35 | leukocyte aggregation (GO:0070486) | 4.05976055 |
| 36 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 4.04565464 |
| 37 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.97422155 |
| 38 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.94203475 |
| 39 | myeloid cell activation involved in immune response (GO:0002275) | 3.92187599 |
| 40 | respiratory burst (GO:0045730) | 3.80279617 |
| 41 | type I interferon signaling pathway (GO:0060337) | 3.77569162 |
| 42 | cellular response to type I interferon (GO:0071357) | 3.77569162 |
| 43 | response to host defenses (GO:0052200) | 3.74560516 |
| 44 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.74560516 |
| 45 | response to host (GO:0075136) | 3.74560516 |
| 46 | response to type I interferon (GO:0034340) | 3.72915478 |
| 47 | neutrophil activation (GO:0042119) | 3.69934915 |
| 48 | regulation of mast cell degranulation (GO:0043304) | 3.66288841 |
| 49 | granulocyte activation (GO:0036230) | 3.65608032 |
| 50 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.64974096 |
| 51 | myeloid leukocyte mediated immunity (GO:0002444) | 3.62587584 |
| 52 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.61379080 |
| 53 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.57377037 |
| 54 | regulation of gamma-delta T cell activation (GO:0046643) | 3.55807531 |
| 55 | positive regulation of interferon-alpha production (GO:0032727) | 3.53959790 |
| 56 | positive regulation of mast cell activation (GO:0033005) | 3.49991811 |
| 57 | positive regulation of type 2 immune response (GO:0002830) | 3.48520027 |
| 58 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.45250988 |
| 59 | positive regulation of mast cell degranulation (GO:0043306) | 3.45250988 |
| 60 | regulation of interferon-alpha production (GO:0032647) | 3.42134900 |
| 61 | regulation of T cell tolerance induction (GO:0002664) | 3.40384239 |
| 62 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.40113561 |
| 63 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.39412090 |
| 64 | regulation of tolerance induction (GO:0002643) | 3.38431611 |
| 65 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.37609179 |
| 66 | phagocytosis, engulfment (GO:0006911) | 3.34247498 |
| 67 | response to muramyl dipeptide (GO:0032495) | 3.33714179 |
| 68 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 3.32368787 |
| 69 | regulation of mast cell activation (GO:0033003) | 3.27062179 |
| 70 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.25411680 |
| 71 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 3.23896142 |
| 72 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.22189049 |
| 73 | regulation of leukocyte degranulation (GO:0043300) | 3.18901358 |
| 74 | cellular response to interferon-gamma (GO:0071346) | 3.16320790 |
| 75 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.14697932 |
| 76 | positive regulation of antigen processing and presentation (GO:0002579) | 3.13525531 |
| 77 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.12811107 |
| 78 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.12385291 |
| 79 | T-helper 1 type immune response (GO:0042088) | 3.10850793 |
| 80 | regulation of antigen processing and presentation (GO:0002577) | 3.09797139 |
| 81 | defense response to protozoan (GO:0042832) | 3.08002790 |
| 82 | phagocytosis, recognition (GO:0006910) | 3.07957788 |
| 83 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.07471365 |
| 84 | neutrophil mediated immunity (GO:0002446) | 3.05689895 |
| 85 | response to interferon-gamma (GO:0034341) | 3.04057673 |
| 86 | neutrophil chemotaxis (GO:0030593) | 3.03870678 |
| 87 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.03142099 |
| 88 | germinal center formation (GO:0002467) | 2.97973777 |
| 89 | regulation of acute inflammatory response to antigenic stimulus (GO:0002864) | 2.97328483 |
| 90 | myeloid leukocyte activation (GO:0002274) | 2.97264701 |
| 91 | neutrophil migration (GO:1990266) | 2.95956190 |
| 92 | response to interferon-beta (GO:0035456) | 2.95263697 |
| 93 | negative regulation of innate immune response (GO:0045824) | 2.94363168 |
| 94 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.94189837 |
| 95 | negative regulation of T cell mediated immunity (GO:0002710) | 2.92768139 |
| 96 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.89873964 |
| 97 | positive regulation of interferon-beta production (GO:0032728) | 2.89832999 |
| 98 | regulation of type 2 immune response (GO:0002828) | 2.89612446 |
| 99 | T cell migration (GO:0072678) | 2.88256993 |
| 100 | response to interferon-alpha (GO:0035455) | 2.85423346 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 6.66862416 |
| 2 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 5.23314857 |
| 3 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.17429746 |
| 4 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.95276957 |
| 5 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.94282737 |
| 6 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.62120545 |
| 7 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.61537173 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.32595972 |
| 9 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 3.17626570 |
| 10 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.13979902 |
| 11 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 3.09677113 |
| 12 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.06635215 |
| 13 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.93309564 |
| 14 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.75787111 |
| 15 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.73949511 |
| 16 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.69604826 |
| 17 | SPI1_23127762_ChIP-Seq_K562_Human | 2.62231149 |
| 18 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.57762092 |
| 19 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.46918790 |
| 20 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.46800270 |
| 21 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.36790887 |
| 22 | VDR_24787735_ChIP-Seq_THP-1_Human | 2.30240437 |
| 23 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.28229071 |
| 24 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.28222409 |
| 25 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.24072126 |
| 26 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.18888656 |
| 27 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 2.13206788 |
| 28 | MYB_26560356_Chip-Seq_TH2_Human | 1.96859732 |
| 29 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.96321208 |
| 30 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.88263319 |
| 31 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.88255137 |
| 32 | MAF_26560356_Chip-Seq_TH1_Human | 1.86177196 |
| 33 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.82829585 |
| 34 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.73852478 |
| 35 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.73123182 |
| 36 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.72762114 |
| 37 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.72147503 |
| 38 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.69526633 |
| 39 | GATA1_22025678_ChIP-Seq_K562_Human | 1.62210895 |
| 40 | MYB_26560356_Chip-Seq_TH1_Human | 1.61650328 |
| 41 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.59200192 |
| 42 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.55409547 |
| 43 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.53386015 |
| 44 | UTX_26944678_Chip-Seq_JUKART_Human | 1.51217659 |
| 45 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.49275861 |
| 46 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.48190139 |
| 47 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.48179205 |
| 48 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.45188255 |
| 49 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.44663151 |
| 50 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.44185162 |
| 51 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.41349453 |
| 52 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.36356242 |
| 53 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.35871141 |
| 54 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.35066347 |
| 55 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.34933410 |
| 56 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.27393662 |
| 57 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.26774689 |
| 58 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.26527890 |
| 59 | GATA3_26560356_Chip-Seq_TH2_Human | 1.26229992 |
| 60 | MAF_26560356_Chip-Seq_TH2_Human | 1.24405857 |
| 61 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.23893960 |
| 62 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.23449921 |
| 63 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.22790383 |
| 64 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.22448410 |
| 65 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.19979961 |
| 66 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.18559580 |
| 67 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.18221323 |
| 68 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.17140626 |
| 69 | MYC_22102868_ChIP-Seq_BL_Human | 1.15443406 |
| 70 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.10957233 |
| 71 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.10153398 |
| 72 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.08745233 |
| 73 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.08172271 |
| 74 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.07508822 |
| 75 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.04839138 |
| 76 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.04715470 |
| 77 | GATA1_19941826_ChIP-Seq_K562_Human | 1.02629737 |
| 78 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.01990210 |
| 79 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.00870224 |
| 80 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.97884597 |
| 81 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.95914389 |
| 82 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.95455647 |
| 83 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.95073928 |
| 84 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.90055718 |
| 85 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.89276884 |
| 86 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.88794214 |
| 87 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.88672739 |
| 88 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.88628744 |
| 89 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.84421980 |
| 90 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.84087156 |
| 91 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.81913963 |
| 92 | GATA2_19941826_ChIP-Seq_K562_Human | 0.81643028 |
| 93 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.79255299 |
| 94 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.78560650 |
| 95 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.75717388 |
| 96 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.73826448 |
| 97 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.72306909 |
| 98 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.70072119 |
| 99 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.68761510 |
| 100 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.65745358 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 4.77209154 |
| 2 | MP0001835_abnormal_antigen_presentation | 4.11845217 |
| 3 | MP0003436_decreased_susceptibility_to | 3.65256313 |
| 4 | MP0003303_peritoneal_inflammation | 3.52634010 |
| 5 | MP0006082_CNS_inflammation | 3.36857405 |
| 6 | MP0009785_altered_susceptibility_to | 3.32782697 |
| 7 | MP0002419_abnormal_innate_immunity | 3.29858611 |
| 8 | MP0005671_abnormal_response_to | 3.07405831 |
| 9 | MP0005025_abnormal_response_to | 2.99952517 |
| 10 | MP0002148_abnormal_hypersensitivity_rea | 2.95936725 |
| 11 | MP0001790_abnormal_immune_system | 2.93290815 |
| 12 | MP0005387_immune_system_phenotype | 2.93290815 |
| 13 | MP0005000_abnormal_immune_tolerance | 2.86357932 |
| 14 | MP0000685_abnormal_immune_system | 2.78829883 |
| 15 | MP0001800_abnormal_humoral_immune | 2.68387169 |
| 16 | MP0003191_abnormal_cellular_cholesterol | 2.59829263 |
| 17 | MP0002452_abnormal_antigen_presenting | 2.55392917 |
| 18 | MP0002723_abnormal_immune_serum | 2.54445119 |
| 19 | MP0003172_abnormal_lysosome_physiology | 2.36218789 |
| 20 | MP0002420_abnormal_adaptive_immunity | 2.30113375 |
| 21 | MP0001819_abnormal_immune_cell | 2.29350383 |
| 22 | MP0003300_gastrointestinal_ulcer | 2.27614836 |
| 23 | MP0005058_abnormal_lysosome_morphology | 2.27538157 |
| 24 | MP0001533_abnormal_skeleton_physiology | 2.12807779 |
| 25 | MP0008260_abnormal_autophagy | 2.09269034 |
| 26 | MP0005464_abnormal_platelet_physiology | 2.08595678 |
| 27 | MP0009840_abnormal_foam_cell | 1.99878731 |
| 28 | MP0009278_abnormal_bone_marrow | 1.98626698 |
| 29 | MP0001845_abnormal_inflammatory_respons | 1.89746340 |
| 30 | MP0009764_decreased_sensitivity_to | 1.80752457 |
| 31 | MP0002405_respiratory_system_inflammati | 1.78111826 |
| 32 | MP0000343_altered_response_to | 1.73334319 |
| 33 | MP0003075_altered_response_to | 1.67053869 |
| 34 | MP0000569_abnormal_digit_pigmentation | 1.66287760 |
| 35 | MP0000716_abnormal_immune_system | 1.65698555 |
| 36 | MP0008469_abnormal_protein_level | 1.63736247 |
| 37 | MP0003828_pulmonary_edema | 1.59836416 |
| 38 | MP0000604_amyloidosis | 1.59357398 |
| 39 | MP0003690_abnormal_glial_cell | 1.57905398 |
| 40 | MP0005310_abnormal_salivary_gland | 1.56568142 |
| 41 | MP0010155_abnormal_intestine_physiology | 1.55417755 |
| 42 | MP0002398_abnormal_bone_marrow | 1.51126123 |
| 43 | MP0005397_hematopoietic_system_phenotyp | 1.49364255 |
| 44 | MP0001545_abnormal_hematopoietic_system | 1.49364255 |
| 45 | MP0002277_abnormal_respiratory_mucosa | 1.49239545 |
| 46 | MP0004883_abnormal_blood_vessel | 1.46873993 |
| 47 | MP0004947_skin_inflammation | 1.46068615 |
| 48 | MP0002998_abnormal_bone_remodeling | 1.44588532 |
| 49 | MP0004510_myositis | 1.40051649 |
| 50 | MP0000465_gastrointestinal_hemorrhage | 1.36788352 |
| 51 | MP0003806_abnormal_nucleotide_metabolis | 1.32231115 |
| 52 | MP0000858_altered_metastatic_potential | 1.31449739 |
| 53 | MP0009333_abnormal_splenocyte_physiolog | 1.29563259 |
| 54 | MP0000689_abnormal_spleen_morphology | 1.28186254 |
| 55 | MP0002429_abnormal_blood_cell | 1.27751941 |
| 56 | MP0005164_abnormal_response_to | 1.27318542 |
| 57 | MP0002166_altered_tumor_susceptibility | 1.27124734 |
| 58 | MP0003763_abnormal_thymus_physiology | 1.20789746 |
| 59 | MP0002722_abnormal_immune_system | 1.20445142 |
| 60 | MP0005451_abnormal_body_composition | 1.18193561 |
| 61 | MP0003183_abnormal_peptide_metabolism | 1.17636335 |
| 62 | MP0003448_altered_tumor_morphology | 1.16459940 |
| 63 | MP0005166_decreased_susceptibility_to | 1.16054732 |
| 64 | MP0003866_abnormal_defecation | 1.10078589 |
| 65 | MP0001853_heart_inflammation | 1.09232335 |
| 66 | MP0002132_abnormal_respiratory_system | 1.04475306 |
| 67 | MP0009763_increased_sensitivity_to | 0.99544077 |
| 68 | MP0005167_abnormal_blood-brain_barrier | 0.99182214 |
| 69 | MP0003195_calcinosis | 0.98578863 |
| 70 | MP0001851_eye_inflammation | 0.91585724 |
| 71 | MP0000920_abnormal_myelination | 0.91432049 |
| 72 | MP0000015_abnormal_ear_pigmentation | 0.89532368 |
| 73 | MP0003656_abnormal_erythrocyte_physiolo | 0.86754039 |
| 74 | MP0002006_tumorigenesis | 0.85295751 |
| 75 | MP0002396_abnormal_hematopoietic_system | 0.83601606 |
| 76 | MP0005390_skeleton_phenotype | 0.81969394 |
| 77 | MP0000703_abnormal_thymus_morphology | 0.79831843 |
| 78 | MP0008004_abnormal_stomach_pH | 0.77975166 |
| 79 | MP0003329_amyloid_beta_deposits | 0.76371636 |
| 80 | MP0000249_abnormal_blood_vessel | 0.75051664 |
| 81 | MP0001663_abnormal_digestive_system | 0.72297893 |
| 82 | MP0004808_abnormal_hematopoietic_stem | 0.69811997 |
| 83 | MP0003795_abnormal_bone_structure | 0.68760855 |
| 84 | MP0004381_abnormal_hair_follicle | 0.67230299 |
| 85 | MP0008874_decreased_physiological_sensi | 0.65980431 |
| 86 | MP0005174_abnormal_tail_pigmentation | 0.62113132 |
| 87 | MP0009765_abnormal_xenobiotic_induced | 0.61732115 |
| 88 | MP0000371_diluted_coat_color | 0.60827227 |
| 89 | MP0002933_joint_inflammation | 0.59557057 |
| 90 | MP0005319_abnormal_enzyme/_coenzyme | 0.57232350 |
| 91 | MP0003221_abnormal_cardiomyocyte_apopto | 0.55369087 |
| 92 | MP0002332_abnormal_exercise_endurance | 0.53524794 |
| 93 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.52694859 |
| 94 | MP0004484_altered_response_of | 0.52043534 |
| 95 | MP0002009_preneoplasia | 0.51784263 |
| 96 | MP0003091_abnormal_cell_migration | 0.50746556 |
| 97 | MP0001542_abnormal_bone_strength | 0.48240766 |
| 98 | MP0000609_abnormal_liver_physiology | 0.46726063 |
| 99 | MP0005165_increased_susceptibility_to | 0.46671130 |
| 100 | MP0001986_abnormal_taste_sensitivity | 0.45799637 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Recurrent bacterial skin infections (HP:0005406) | 6.54405916 |
| 2 | Recurrent abscess formation (HP:0002722) | 6.38187388 |
| 3 | Eczematoid dermatitis (HP:0000976) | 6.09662529 |
| 4 | Abnormality of macrophages (HP:0004311) | 5.72188102 |
| 5 | Myositis (HP:0100614) | 5.28737692 |
| 6 | Orchitis (HP:0100796) | 5.13309190 |
| 7 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.96256229 |
| 8 | Optic neuritis (HP:0100653) | 4.94260350 |
| 9 | Retrobulbar optic neuritis (HP:0100654) | 4.94260350 |
| 10 | Systemic lupus erythematosus (HP:0002725) | 4.89594376 |
| 11 | Mediastinal lymphadenopathy (HP:0100721) | 4.33766488 |
| 12 | Recurrent skin infections (HP:0001581) | 4.20643820 |
| 13 | Stomatitis (HP:0010280) | 4.12578935 |
| 14 | Abnormality of liposaccharide metabolism (HP:0010968) | 4.10857409 |
| 15 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 4.10857409 |
| 16 | Abnormality of glycolipid metabolism (HP:0010969) | 4.10857409 |
| 17 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.06744319 |
| 18 | Obstructive lung disease (HP:0006536) | 3.84475658 |
| 19 | Chronic obstructive pulmonary disease (HP:0006510) | 3.84475658 |
| 20 | Recurrent fungal infections (HP:0002841) | 3.79543819 |
| 21 | Spontaneous hematomas (HP:0007420) | 3.77928100 |
| 22 | Gingivitis (HP:0000230) | 3.68424918 |
| 23 | Gastrointestinal infarctions (HP:0005244) | 3.67685037 |
| 24 | Recurrent cutaneous fungal infections (HP:0011370) | 3.64339914 |
| 25 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.64339914 |
| 26 | Meningitis (HP:0001287) | 3.61662160 |
| 27 | Keratoconjunctivitis sicca (HP:0001097) | 3.46882184 |
| 28 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.36615045 |
| 29 | Glomerulonephritis (HP:0000099) | 3.35006352 |
| 30 | Amyloidosis (HP:0011034) | 3.26202268 |
| 31 | Hemoptysis (HP:0002105) | 3.21430002 |
| 32 | Keratoconjunctivitis (HP:0001096) | 3.19695455 |
| 33 | Encephalitis (HP:0002383) | 3.18425356 |
| 34 | Urticaria (HP:0001025) | 3.18126216 |
| 35 | Increased cerebral lipofuscin (HP:0011813) | 3.10940438 |
| 36 | Vasculitis (HP:0002633) | 3.08905780 |
| 37 | Pulmonary infiltrates (HP:0002113) | 3.06812440 |
| 38 | Disinhibition (HP:0000734) | 2.99841894 |
| 39 | Loss of speech (HP:0002371) | 2.80974366 |
| 40 | Chest pain (HP:0100749) | 2.78156327 |
| 41 | Peritonitis (HP:0002586) | 2.73101234 |
| 42 | Cellulitis (HP:0100658) | 2.73055034 |
| 43 | Arterial thrombosis (HP:0004420) | 2.67684398 |
| 44 | Episodic fever (HP:0001954) | 2.64185338 |
| 45 | Recurrent viral infections (HP:0004429) | 2.62530574 |
| 46 | Premature loss of primary teeth (HP:0006323) | 2.61841420 |
| 47 | Osteomyelitis (HP:0002754) | 2.58713592 |
| 48 | Leukocytosis (HP:0001974) | 2.53913074 |
| 49 | Gingival bleeding (HP:0000225) | 2.53748081 |
| 50 | Vacuolated lymphocytes (HP:0001922) | 2.53516098 |
| 51 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.53100625 |
| 52 | Anorexia (HP:0002039) | 2.51853464 |
| 53 | T lymphocytopenia (HP:0005403) | 2.50147154 |
| 54 | Increased IgE level (HP:0003212) | 2.49266402 |
| 55 | Abnormality of T cell number (HP:0011839) | 2.48585263 |
| 56 | Pulmonary embolism (HP:0002204) | 2.46444180 |
| 57 | Mutism (HP:0002300) | 2.46040262 |
| 58 | Dysostosis multiplex (HP:0000943) | 2.45550777 |
| 59 | Chronic otitis media (HP:0000389) | 2.45494640 |
| 60 | Pustule (HP:0200039) | 2.43975154 |
| 61 | Epistaxis (HP:0000421) | 2.41072098 |
| 62 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.37952770 |
| 63 | Prolonged bleeding time (HP:0003010) | 2.35905362 |
| 64 | Petechiae (HP:0000967) | 2.33199478 |
| 65 | Autoimmune thrombocytopenia (HP:0001973) | 2.32607588 |
| 66 | Abnormality of the peritoneum (HP:0002585) | 2.31499185 |
| 67 | Increased serum ferritin (HP:0003281) | 2.30659765 |
| 68 | Increased IgM level (HP:0003496) | 2.30579956 |
| 69 | Purpura (HP:0000979) | 2.28892893 |
| 70 | Complement deficiency (HP:0004431) | 2.27713178 |
| 71 | Gangrene (HP:0100758) | 2.23088505 |
| 72 | Abnormality of the pleura (HP:0002103) | 2.20407091 |
| 73 | Inflammation of the large intestine (HP:0002037) | 2.17623393 |
| 74 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.15386631 |
| 75 | Abnormality of iron homeostasis (HP:0011031) | 2.13501484 |
| 76 | Abnormality of the endocardium (HP:0004306) | 2.10749792 |
| 77 | Hypergammaglobulinemia (HP:0010702) | 2.10642050 |
| 78 | Panhypogammaglobulinemia (HP:0003139) | 2.09912237 |
| 79 | Vertigo (HP:0002321) | 2.08663394 |
| 80 | Cheilitis (HP:0100825) | 2.07604741 |
| 81 | Gastrointestinal inflammation (HP:0004386) | 2.06383800 |
| 82 | Malnutrition (HP:0004395) | 2.04107409 |
| 83 | Abnormality of T cells (HP:0002843) | 2.02876148 |
| 84 | Agnosia (HP:0010524) | 2.02015985 |
| 85 | Glomerulopathy (HP:0100820) | 2.01550444 |
| 86 | Hepatosplenomegaly (HP:0001433) | 2.00830925 |
| 87 | Sepsis (HP:0100806) | 2.00400276 |
| 88 | Hypochromic anemia (HP:0001931) | 1.99984259 |
| 89 | Abnormality of complement system (HP:0005339) | 1.99910227 |
| 90 | Axonal loss (HP:0003447) | 1.98049427 |
| 91 | Pathologic fracture (HP:0002756) | 1.97881919 |
| 92 | Polyneuropathy (HP:0001271) | 1.96117070 |
| 93 | Granulocytopenia (HP:0001913) | 1.95095664 |
| 94 | Colitis (HP:0002583) | 1.93567434 |
| 95 | Upper motor neuron abnormality (HP:0002127) | 1.93040524 |
| 96 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.90776260 |
| 97 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.90776260 |
| 98 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.90776260 |
| 99 | Skin ulcer (HP:0200042) | 1.86951559 |
| 100 | Slow saccadic eye movements (HP:0000514) | 1.85378894 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 4.66996303 |
| 2 | BLK | 4.49422343 |
| 3 | TYK2 | 3.38519848 |
| 4 | IRAK4 | 2.98247944 |
| 5 | MAP4K1 | 2.90921010 |
| 6 | MAP2K3 | 2.87870638 |
| 7 | CSK | 2.73760730 |
| 8 | ERN1 | 2.48648192 |
| 9 | JAK3 | 2.33839233 |
| 10 | FES | 2.25045770 |
| 11 | FGR | 2.17321813 |
| 12 | ZAP70 | 2.13269816 |
| 13 | MAP3K14 | 2.06152902 |
| 14 | TNK2 | 2.05270544 |
| 15 | TXK | 1.91756949 |
| 16 | IKBKE | 1.91595794 |
| 17 | SYK | 1.80825333 |
| 18 | TBK1 | 1.80339878 |
| 19 | JAK1 | 1.74703757 |
| 20 | CSF1R | 1.73099910 |
| 21 | KIT | 1.69236355 |
| 22 | BTK | 1.68061599 |
| 23 | TGFBR2 | 1.64906287 |
| 24 | LYN | 1.60641936 |
| 25 | GRK6 | 1.58975410 |
| 26 | MATK | 1.57400060 |
| 27 | JAK2 | 1.56718913 |
| 28 | HCK | 1.56172414 |
| 29 | MAP3K3 | 1.51461358 |
| 30 | MAP3K11 | 1.50875144 |
| 31 | MAP3K13 | 1.48282087 |
| 32 | TAOK1 | 1.48132583 |
| 33 | GRK7 | 1.41863164 |
| 34 | EPHB1 | 1.38358792 |
| 35 | IRAK3 | 1.31694815 |
| 36 | BMPR2 | 1.26284489 |
| 37 | PRPF4B | 1.22913884 |
| 38 | IKBKB | 1.22720488 |
| 39 | MAP3K6 | 1.22402777 |
| 40 | TAOK3 | 1.22302655 |
| 41 | LCK | 1.16954188 |
| 42 | MAP3K1 | 1.10251766 |
| 43 | CAMK1D | 1.09530091 |
| 44 | ITK | 1.04904358 |
| 45 | YES1 | 1.03996079 |
| 46 | TEC | 1.01998778 |
| 47 | IRAK1 | 0.97236124 |
| 48 | CDC42BPA | 0.92455794 |
| 49 | TAOK2 | 0.89574936 |
| 50 | MARK3 | 0.84007745 |
| 51 | PDK1 | 0.81645269 |
| 52 | MAP3K5 | 0.81451288 |
| 53 | IRAK2 | 0.79005795 |
| 54 | MARK2 | 0.78612825 |
| 55 | PDPK1 | 0.75560200 |
| 56 | KSR2 | 0.72834945 |
| 57 | STK10 | 0.69797001 |
| 58 | FGFR4 | 0.67117532 |
| 59 | FYN | 0.65433471 |
| 60 | PIK3CG | 0.64683010 |
| 61 | SIK3 | 0.62694966 |
| 62 | FGFR3 | 0.59217250 |
| 63 | MAP2K4 | 0.58999144 |
| 64 | MAPK12 | 0.58167973 |
| 65 | MAP2K6 | 0.58100148 |
| 66 | TESK2 | 0.58045885 |
| 67 | MOS | 0.57329698 |
| 68 | CDK6 | 0.55237994 |
| 69 | CAMK1G | 0.54855753 |
| 70 | EPHA3 | 0.53876357 |
| 71 | MAPK7 | 0.52825927 |
| 72 | PRKD2 | 0.51716938 |
| 73 | LRRK2 | 0.49160651 |
| 74 | CAMKK2 | 0.48475791 |
| 75 | RPS6KC1 | 0.47076888 |
| 76 | RPS6KL1 | 0.47076888 |
| 77 | CDK19 | 0.46826320 |
| 78 | PIM1 | 0.46347733 |
| 79 | PTK6 | 0.45374814 |
| 80 | ABL1 | 0.44697915 |
| 81 | MAPKAPK2 | 0.40427318 |
| 82 | PTK2B | 0.38975210 |
| 83 | RPS6KA6 | 0.38459377 |
| 84 | HIPK2 | 0.37826939 |
| 85 | RET | 0.37157495 |
| 86 | DMPK | 0.35719921 |
| 87 | PRKCD | 0.35715110 |
| 88 | CHUK | 0.35332464 |
| 89 | DAPK2 | 0.34554989 |
| 90 | SGK3 | 0.34455252 |
| 91 | CAMK4 | 0.34360397 |
| 92 | KSR1 | 0.34241171 |
| 93 | MAP3K7 | 0.33058696 |
| 94 | MAP3K2 | 0.33048523 |
| 95 | RIPK1 | 0.33006644 |
| 96 | SIK2 | 0.31123282 |
| 97 | PRKCQ | 0.30621511 |
| 98 | STK11 | 0.29530101 |
| 99 | EGFR | 0.28381265 |
| 100 | PRKG2 | 0.28095827 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 4.16558854 |
| 2 | Leishmaniasis_Homo sapiens_hsa05140 | 3.42032099 |
| 3 | Osteoclast differentiation_Homo sapiens_hsa04380 | 3.06896499 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 2.78340780 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.64929114 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.53406877 |
| 7 | Tuberculosis_Homo sapiens_hsa05152 | 2.46646476 |
| 8 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.45017082 |
| 9 | Asthma_Homo sapiens_hsa05310 | 2.22952868 |
| 10 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.14649852 |
| 11 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.11803858 |
| 12 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.10048555 |
| 13 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.08178437 |
| 14 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.99749906 |
| 15 | Phagosome_Homo sapiens_hsa04145 | 1.94094626 |
| 16 | Other glycan degradation_Homo sapiens_hsa00511 | 1.93056358 |
| 17 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.92250984 |
| 18 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.90952970 |
| 19 | Legionellosis_Homo sapiens_hsa05134 | 1.89713101 |
| 20 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.84222350 |
| 21 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.78907643 |
| 22 | Malaria_Homo sapiens_hsa05144 | 1.78902790 |
| 23 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.70738526 |
| 24 | Influenza A_Homo sapiens_hsa05164 | 1.66857281 |
| 25 | Viral myocarditis_Homo sapiens_hsa05416 | 1.65566517 |
| 26 | Lysosome_Homo sapiens_hsa04142 | 1.65429577 |
| 27 | Pertussis_Homo sapiens_hsa05133 | 1.63622038 |
| 28 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.62678320 |
| 29 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.61798139 |
| 30 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.60091415 |
| 31 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.59519524 |
| 32 | Measles_Homo sapiens_hsa05162 | 1.52950315 |
| 33 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.38261040 |
| 34 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.34070704 |
| 35 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.32870426 |
| 36 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.29697457 |
| 37 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.29284263 |
| 38 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.21707675 |
| 39 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.15711202 |
| 40 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.14788931 |
| 41 | Salmonella infection_Homo sapiens_hsa05132 | 1.13777191 |
| 42 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.08721657 |
| 43 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.07278875 |
| 44 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.05199530 |
| 45 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.04263066 |
| 46 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.99941551 |
| 47 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.97348572 |
| 48 | Hepatitis C_Homo sapiens_hsa05160 | 0.93408277 |
| 49 | Hepatitis B_Homo sapiens_hsa05161 | 0.90722187 |
| 50 | Platelet activation_Homo sapiens_hsa04611 | 0.88101282 |
| 51 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.87370801 |
| 52 | Shigellosis_Homo sapiens_hsa05131 | 0.85728119 |
| 53 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.82279939 |
| 54 | Apoptosis_Homo sapiens_hsa04210 | 0.80206321 |
| 55 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.78528095 |
| 56 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.76914504 |
| 57 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.75259492 |
| 58 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.65712963 |
| 59 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.65467700 |
| 60 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.62608874 |
| 61 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.62431239 |
| 62 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.61191674 |
| 63 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.60496360 |
| 64 | Amoebiasis_Homo sapiens_hsa05146 | 0.59907788 |
| 65 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.58610074 |
| 66 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.58398796 |
| 67 | Prion diseases_Homo sapiens_hsa05020 | 0.57469201 |
| 68 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.56974527 |
| 69 | Endocytosis_Homo sapiens_hsa04144 | 0.53551311 |
| 70 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.53174520 |
| 71 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.52246667 |
| 72 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.52156290 |
| 73 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.50816551 |
| 74 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.49821100 |
| 75 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.46792721 |
| 76 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.46392902 |
| 77 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.44632013 |
| 78 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.44523912 |
| 79 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.43452624 |
| 80 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.43433667 |
| 81 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.42581257 |
| 82 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.39684070 |
| 83 | HTLV-I infection_Homo sapiens_hsa05166 | 0.39178763 |
| 84 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.39010871 |
| 85 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.36973771 |
| 86 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.36188415 |
| 87 | Galactose metabolism_Homo sapiens_hsa00052 | 0.35704818 |
| 88 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.30601297 |
| 89 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.30559303 |
| 90 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.29882520 |
| 91 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.24168816 |
| 92 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.23618309 |
| 93 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.23211744 |
| 94 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.21311970 |
| 95 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.19257504 |
| 96 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.19098813 |
| 97 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.18786354 |
| 98 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.17304729 |
| 99 | Insulin resistance_Homo sapiens_hsa04931 | 0.16204641 |
| 100 | Bladder cancer_Homo sapiens_hsa05219 | 0.16012499 |

