FCHO1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)5.55272650
2antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.48337312
3antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.87942344
4antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.87942344
5positive regulation by symbiont of host defense response (GO:0052509)4.67257135
6modulation by symbiont of host defense response (GO:0052031)4.67257135
7modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.67257135
8modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.67257135
9positive regulation by organism of defense response of other organism involved in symbiotic interact4.67257135
10modulation by symbiont of host immune response (GO:0052553)4.67257135
11negative regulation of cell killing (GO:0031342)4.52843930
12negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.52843930
13neutrophil activation involved in immune response (GO:0002283)4.51353899
14regulation of gamma-delta T cell differentiation (GO:0045586)4.49272537
15positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.37547234
16antigen processing and presentation of endogenous antigen (GO:0019883)4.36660770
17B cell receptor signaling pathway (GO:0050853)4.24186095
18detection of bacterium (GO:0016045)4.21952990
19detection of other organism (GO:0098543)4.18167392
20negative regulation of lymphocyte mediated immunity (GO:0002707)4.16018602
21negative T cell selection (GO:0043383)4.01005978
22regulation of gamma-delta T cell activation (GO:0046643)4.00457165
23negative thymic T cell selection (GO:0045060)3.91677390
24response to interleukin-15 (GO:0070672)3.90651949
25cellular extravasation (GO:0045123)3.90624135
26mast cell activation involved in immune response (GO:0002279)3.89570278
27mast cell degranulation (GO:0043303)3.89570278
28positive regulation of B cell differentiation (GO:0045579)3.84111443
29macrophage activation involved in immune response (GO:0002281)3.77386708
30negative regulation of leukocyte mediated immunity (GO:0002704)3.74649189
31immunoglobulin mediated immune response (GO:0016064)3.73938328
32neutrophil activation (GO:0042119)3.71543285
33mast cell activation (GO:0045576)3.65036156
34respiratory burst (GO:0045730)3.64456098
35T cell homeostasis (GO:0043029)3.56543177
36response to peptidoglycan (GO:0032494)3.53634159
37positive regulation of granulocyte differentiation (GO:0030854)3.53444289
38V(D)J recombination (GO:0033151)3.51161342
39regulation of B cell receptor signaling pathway (GO:0050855)3.48618725
40positive thymic T cell selection (GO:0045059)3.47768781
41T cell selection (GO:0045058)3.47760056
42leukocyte degranulation (GO:0043299)3.45341731
43cellular response to interleukin-15 (GO:0071350)3.43553468
44myeloid cell activation involved in immune response (GO:0002275)3.42537771
45regulation of mast cell degranulation (GO:0043304)3.42025308
46positive T cell selection (GO:0043368)3.40106405
47regulation of B cell differentiation (GO:0045577)3.37498137
48thymic T cell selection (GO:0045061)3.36331974
49leukocyte migration involved in inflammatory response (GO:0002523)3.36304694
50defense response to protozoan (GO:0042832)3.34592792
51DNA unwinding involved in DNA replication (GO:0006268)3.32825308
52antigen receptor-mediated signaling pathway (GO:0050851)3.30912609
53regulation of interferon-beta biosynthetic process (GO:0045357)3.29851367
54G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.29838985
55response to muramyl dipeptide (GO:0032495)3.29745888
56positive regulation of mast cell activation (GO:0033005)3.29263292
57granulocyte activation (GO:0036230)3.28167221
58negative regulation of interleukin-12 production (GO:0032695)3.27011238
59negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.26361405
60response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.23200150
61response to host immune response (GO:0052572)3.23200150
62Peyers patch development (GO:0048541)3.22307445
63mucosal-associated lymphoid tissue development (GO:0048537)3.22307445
64germinal center formation (GO:0002467)3.20131303
65T cell migration (GO:0072678)3.20116429
66regulation of mast cell activation involved in immune response (GO:0033006)3.18866496
67detection of external biotic stimulus (GO:0098581)3.18340742
68T cell receptor signaling pathway (GO:0050852)3.18054225
69regulation of regulatory T cell differentiation (GO:0045589)3.17451967
70negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.16402059
71regulation of myeloid leukocyte mediated immunity (GO:0002886)3.14609255
72regulation of mast cell activation (GO:0033003)3.13808918
73positive regulation of Rap GTPase activity (GO:0032854)3.13534531
74regulation of natural killer cell mediated immunity (GO:0002715)3.09723006
75regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.09723006
76ribosomal small subunit assembly (GO:0000028)3.08933683
77antigen processing and presentation via MHC class Ib (GO:0002475)3.08274562
78microglial cell activation (GO:0001774)3.07753614
79negative regulation of phagocytosis (GO:0050765)3.07355618
80neutrophil mediated immunity (GO:0002446)3.07252959
81viral transcription (GO:0019083)3.04924186
82natural killer cell differentiation (GO:0001779)3.03291026
83response to protozoan (GO:0001562)3.02776026
84regulation of T cell mediated cytotoxicity (GO:0001914)3.02277726
85B cell mediated immunity (GO:0019724)2.97900131
86regulation of leukocyte degranulation (GO:0043300)2.92809704
87positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.91365902
88synaptic vesicle maturation (GO:0016188)2.91343166
89lymphocyte homeostasis (GO:0002260)2.91143321
90positive regulation of T cell mediated cytotoxicity (GO:0001916)2.90708211
91regulation of T cell tolerance induction (GO:0002664)2.90280783
92leukocyte aggregation (GO:0070486)2.90189935
93response to host (GO:0075136)2.88840817
94response to host defenses (GO:0052200)2.88840817
95response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.88840817
96negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.88800805
97regulation of Rap GTPase activity (GO:0032317)2.88192549
98signal complex assembly (GO:0007172)2.87971676
99regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.87584623
100cellular response to type I interferon (GO:0071357)2.86985669
101type I interferon signaling pathway (GO:0060337)2.86985669
102response to type I interferon (GO:0034340)2.86517122
103positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.86357077
104tolerance induction (GO:0002507)2.84932280
105translational termination (GO:0006415)2.84774540
106locomotory exploration behavior (GO:0035641)2.83424716
107interferon-gamma production (GO:0032609)2.82748187
108negative regulation of innate immune response (GO:0045824)2.81831202
109regulation of regulated secretory pathway (GO:1903305)2.80565075
110DNA strand elongation involved in DNA replication (GO:0006271)2.78957961
111negative regulation of RNA splicing (GO:0033119)2.77623669
112T cell costimulation (GO:0031295)2.76716329
113positive regulation of gene expression, epigenetic (GO:0045815)2.76319537
114positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.75466759
115nucleosome disassembly (GO:0006337)2.75418080
116protein-DNA complex disassembly (GO:0032986)2.75418080
117lymphocyte costimulation (GO:0031294)2.72997243
118negative regulation of histone methylation (GO:0031061)2.70282899
119telomere maintenance via semi-conservative replication (GO:0032201)2.66418628
120DNA strand elongation (GO:0022616)2.64747257
121regulation of T cell receptor signaling pathway (GO:0050856)2.63300201
122positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.63267526
123megakaryocyte development (GO:0035855)2.61656266
124negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.60710158
125immune response-activating cell surface receptor signaling pathway (GO:0002429)2.60214247
126leukocyte homeostasis (GO:0001776)2.60046655
127negative regulation of erythrocyte differentiation (GO:0045647)2.59478025
128ncRNA 3-end processing (GO:0043628)2.57393780
129translational elongation (GO:0006414)2.54511448
130Arp2/3 complex-mediated actin nucleation (GO:0034314)2.50609799
131regulation of isotype switching to IgG isotypes (GO:0048302)2.49158577
132nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.46918893
133positive regulation of interleukin-2 production (GO:0032743)2.46554385
134regulation of ARF protein signal transduction (GO:0032012)2.45474672
135mature B cell differentiation (GO:0002335)2.43188215
136regulation of defense response to virus by virus (GO:0050690)2.42831360
137regulation of ARF GTPase activity (GO:0032312)2.41135880
138protein complex disassembly (GO:0043241)2.39377788
139adaptation of signaling pathway (GO:0023058)2.38864591
140regulation of histone H3-K9 methylation (GO:0051570)2.38610341
141cellular protein complex disassembly (GO:0043624)2.37745422
142regulation of granulocyte differentiation (GO:0030852)2.37429489
143regulation of short-term neuronal synaptic plasticity (GO:0048172)2.37285289
144activated T cell proliferation (GO:0050798)2.36070979
145positive regulation of lamellipodium assembly (GO:0010592)2.35121092
146regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.34867431
147synaptic vesicle exocytosis (GO:0016079)2.33480007
148protein localization to kinetochore (GO:0034501)2.33421462
149positive regulation of histone deacetylation (GO:0031065)2.32842743
150cellular response to interleukin-4 (GO:0071353)2.31490587
151regulation of histone H3-K4 methylation (GO:0051569)2.31234061
152regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.30814954
153negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.29203012
154ribosomal small subunit biogenesis (GO:0042274)2.25216562
155natural killer cell activation (GO:0030101)2.25043499
156negative regulation of T cell mediated immunity (GO:0002710)2.23363876
157regulation of erythrocyte differentiation (GO:0045646)2.22789351
158regulation of alpha-beta T cell proliferation (GO:0046640)2.22273060
159positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.21561516

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.19016952
2MYC_22102868_ChIP-Seq_BL_Human4.56958105
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.66037736
4VDR_21846776_ChIP-Seq_THP-1_Human3.58638323
5BP1_19119308_ChIP-ChIP_Hs578T_Human3.29634302
6FOXM1_23109430_ChIP-Seq_U2OS_Human3.01632235
7MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.97857600
8SCL_19346495_ChIP-Seq_HPC-7_Human2.96435050
9FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.64371313
10EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.57130642
11EGR1_19374776_ChIP-ChIP_THP-1_Human2.54204978
12MAF_26560356_Chip-Seq_TH1_Human2.42547578
13* TCF7_22412390_ChIP-Seq_EML_Mouse2.41556007
14* UTX_26944678_Chip-Seq_JUKART_Human2.40489795
15SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.36247733
16IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.34426176
17* MYB_26560356_Chip-Seq_TH2_Human2.29317957
18RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.27706184
19CIITA_25753668_ChIP-Seq_RAJI_Human2.27235628
20FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.24992293
21VDR_24763502_ChIP-Seq_THP-1_Human2.21166576
22IRF8_22096565_ChIP-ChIP_GC-B_Human2.20832022
23KDM2B_26808549_Chip-Seq_DND41_Human2.20678170
24KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.18286644
25RUNX_20019798_ChIP-Seq_JUKART_Human2.18035980
26SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.12960771
27* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.12821374
28E2F4_17652178_ChIP-ChIP_JURKAT_Human2.09249881
29KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.03447119
30* MYB_26560356_Chip-Seq_TH1_Human2.01775594
31KDM2B_26808549_Chip-Seq_SUP-B15_Human2.01287810
32STAT4_19710469_ChIP-ChIP_TH1__Mouse1.89921019
33* RUNX1_22412390_ChIP-Seq_EML_Mouse1.84129610
34MAF_26560356_Chip-Seq_TH2_Human1.80744013
35TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.80561912
36MYB_21317192_ChIP-Seq_ERMYB_Mouse1.80090819
37SPI1_23127762_ChIP-Seq_K562_Human1.74576678
38VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.71366592
39* RARB_27405468_Chip-Seq_BRAIN_Mouse1.70232632
40STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.66133331
41FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.63269026
42* SPI1_23547873_ChIP-Seq_NB4_Human1.59427769
43IKZF1_21737484_ChIP-ChIP_HCT116_Human1.59066762
44ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.58428155
45TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.58093251
46EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.57137259
47GATA1_19941827_ChIP-Seq_MEL_Mouse1.48494335
48BCOR_27268052_Chip-Seq_Bcells_Human1.45794695
49KDM2B_26808549_Chip-Seq_JURKAT_Human1.44957428
50EZH2_22144423_ChIP-Seq_EOC_Human1.44882716
51MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.44169616
52NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.44142770
53THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.43393488
54SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.42689728
55GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.39315140
56MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.38308174
57BRD4_27068464_Chip-Seq_AML-cells_Mouse1.38259011
58SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.36409867
59ELF1_17652178_ChIP-ChIP_JURKAT_Human1.35692899
60CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.35118433
61* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.34583589
62LXR_22292898_ChIP-Seq_THP-1_Human1.31918883
63GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.30517887
64SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.29390379
65GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.29043942
66HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.28256468
67IRF8_21731497_ChIP-ChIP_J774_Mouse1.27883271
68GATA3_26560356_Chip-Seq_TH2_Human1.25763769
69TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.24790770
70ELK3_25401928_ChIP-Seq_HUVEC_Human1.23569258
71CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.23523920
72LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.23391309
73GATA3_27048872_Chip-Seq_THYMUS_Human1.23251810
74SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.21461120
75PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.21412396
76XRN2_22483619_ChIP-Seq_HELA_Human1.21391406
77PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.21288508
78NCOR1_26117541_ChIP-Seq_K562_Human1.20147020
79FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.20069854
80RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.17331084
81* DNAJC2_21179169_ChIP-ChIP_NT2_Human1.17291390
82CTCF_27219007_Chip-Seq_ERYTHROID_Human1.16532417
83MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.16321743
84CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.15246332
85MYC_19079543_ChIP-ChIP_MESCs_Mouse1.15025806
86GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.14985037
87EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.14782067
88NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.14774575
89CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.14685214
90SA1_27219007_Chip-Seq_ERYTHROID_Human1.14354227
91GATA1_19941826_ChIP-Seq_K562_Human1.13509094
92ELF1_20517297_ChIP-Seq_JURKAT_Human1.13065798
93ERG_20887958_ChIP-Seq_HPC-7_Mouse1.12248598
94E2F1_21310950_ChIP-Seq_MCF-7_Human1.11990290
95FOXP3_21729870_ChIP-Seq_TREG_Human1.11229016
96IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.10878146
97SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.10390877
98VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.09790115
99LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.09720284
100PU.1_20513432_ChIP-Seq_Bcells_Mouse1.08640160
101DROSHA_22980978_ChIP-Seq_HELA_Human1.08587009
102GATA2_22383799_ChIP-Seq_G1ME_Mouse1.08377920
103SPI1_20517297_ChIP-Seq_HL60_Human1.07729394
104IRF8_27001747_Chip-Seq_BMDM_Mouse1.06855424
105CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.06098684
106SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.05715962
107E2F1_20622854_ChIP-Seq_HELA_Human1.05157217
108CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.03148441
109P300_27268052_Chip-Seq_Bcells_Human1.02608251
110RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.01862261
111THAP11_20581084_ChIP-Seq_MESCs_Mouse1.00439383
112PHF8_20622854_ChIP-Seq_HELA_Human1.00346234
113FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.99434320
114SRY_22984422_ChIP-ChIP_TESTIS_Rat0.99026336
115RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.98905824
116MYC_18555785_ChIP-Seq_MESCs_Mouse0.98611933
117NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.97876193
118SMC4_20622854_ChIP-Seq_HELA_Human0.97607121
119* VDR_23849224_ChIP-Seq_CD4+_Human0.96741953
120CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.96360056
121CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.95810360
122NOTCH1_21737748_ChIP-Seq_TLL_Human0.95339987
123P68_20966046_ChIP-Seq_HELA_Human0.94126154
124* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.92696965
125NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.92383772
126BCL6_27268052_Chip-Seq_Bcells_Human0.91162954
127HOXB4_20404135_ChIP-ChIP_EML_Mouse0.90701601
128SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.90429232
129CTCF_21964334_ChIP-Seq_BJAB-B_Human0.90381729

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity3.56735568
2MP0003724_increased_susceptibility_to3.54338130
3MP0002396_abnormal_hematopoietic_system3.12782925
4MP0003763_abnormal_thymus_physiology3.08630030
5MP0000685_abnormal_immune_system2.80457317
6MP0005671_abnormal_response_to2.71756523
7MP0001800_abnormal_humoral_immune2.66778219
8MP0001835_abnormal_antigen_presentation2.64698938
9MP0002398_abnormal_bone_marrow2.61051356
10MP0002822_catalepsy2.26587538
11MP0002420_abnormal_adaptive_immunity2.22217624
12MP0003303_peritoneal_inflammation2.20752987
13MP0000703_abnormal_thymus_morphology2.19302177
14MP0001790_abnormal_immune_system2.18561180
15MP0005387_immune_system_phenotype2.18561180
16MP0001819_abnormal_immune_cell2.17743579
17MP0002723_abnormal_immune_serum2.11642583
18MP0003880_abnormal_central_pattern2.10377566
19MP0000716_abnormal_immune_system2.09837294
20MP0002452_abnormal_antigen_presenting2.09430940
21MP0004808_abnormal_hematopoietic_stem2.07203484
22MP0002722_abnormal_immune_system2.01790322
23MP0003635_abnormal_synaptic_transmissio2.01465377
24MP0000689_abnormal_spleen_morphology1.99612151
25MP0005000_abnormal_immune_tolerance1.96518338
26MP0001873_stomach_inflammation1.94614177
27MP0010094_abnormal_chromosome_stability1.86001452
28MP0008260_abnormal_autophagy1.83169876
29MP0003866_abnormal_defecation1.81864648
30MP0002429_abnormal_blood_cell1.79725665
31MP0005174_abnormal_tail_pigmentation1.76872278
32MP0005397_hematopoietic_system_phenotyp1.76784312
33MP0001545_abnormal_hematopoietic_system1.76784312
34MP0005423_abnormal_somatic_nervous1.69762161
35MP0002132_abnormal_respiratory_system1.67126792
36MP0005464_abnormal_platelet_physiology1.66685612
37MP0004381_abnormal_hair_follicle1.66167598
38MP0005025_abnormal_response_to1.64825186
39MP0009333_abnormal_splenocyte_physiolog1.63400839
40MP0009745_abnormal_behavioral_response1.60373663
41MP0009785_altered_susceptibility_to1.59421233
42MP0002166_altered_tumor_susceptibility1.58242678
43MP0009278_abnormal_bone_marrow1.56502709
44MP0003111_abnormal_nucleus_morphology1.53132115
45MP0002063_abnormal_learning/memory/cond1.51134007
46MP0001533_abnormal_skeleton_physiology1.49261513
47MP0001986_abnormal_taste_sensitivity1.48630387
48MP0008569_lethality_at_weaning1.48001368
49MP0003183_abnormal_peptide_metabolism1.47281922
50MP0002064_seizures1.46297587
51MP0003300_gastrointestinal_ulcer1.45084232
52MP0002405_respiratory_system_inflammati1.44151029
53MP0001968_abnormal_touch/_nociception1.42000621
54MP0003436_decreased_susceptibility_to1.37711743
55MP0000465_gastrointestinal_hemorrhage1.37644967
56MP0010155_abnormal_intestine_physiology1.37452028
57MP0008057_abnormal_DNA_replication1.37210114
58MP0002006_tumorigenesis1.34601777
59MP0003077_abnormal_cell_cycle1.29770418
60MP0008961_abnormal_basal_metabolism1.29544814
61MP0000490_abnormal_crypts_of1.25512202
62MP0002419_abnormal_innate_immunity1.24991849
63MP0004510_myositis1.20944380
64MP0002572_abnormal_emotion/affect_behav1.18652512
65MP0005310_abnormal_salivary_gland1.15483549
66MP0001529_abnormal_vocalization1.15439403
67MP0005075_abnormal_melanosome_morpholog1.14055455
68MP0002019_abnormal_tumor_incidence1.13345797
69MP0004947_skin_inflammation1.12849701
70MP0008469_abnormal_protein_level1.12418976
71MP0003787_abnormal_imprinting1.11711582
72MP0003191_abnormal_cellular_cholesterol1.11041177
73MP0003693_abnormal_embryo_hatching1.09387059
74MP0003172_abnormal_lysosome_physiology1.08600014
75MP0004811_abnormal_neuron_physiology1.08593520
76MP0009046_muscle_twitch1.07885799
77MP0000015_abnormal_ear_pigmentation1.07791683
78MP0002095_abnormal_skin_pigmentation1.06936478
79MP0002736_abnormal_nociception_after1.05506028
80MP0002272_abnormal_nervous_system1.04713934
81MP0003656_abnormal_erythrocyte_physiolo1.04216549
82MP0005645_abnormal_hypothalamus_physiol1.03971005
83MP0002148_abnormal_hypersensitivity_rea1.03636126
84MP0005409_darkened_coat_color1.03370914
85MP0001851_eye_inflammation0.99800432
86MP0002138_abnormal_hepatobiliary_system0.99159982
87MP0008874_decreased_physiological_sensi0.98990458
88MP0005451_abnormal_body_composition0.96732433
89MP0001845_abnormal_inflammatory_respons0.96331649
90MP0001486_abnormal_startle_reflex0.93248214
91MP0009764_decreased_sensitivity_to0.92342988
92MP0002735_abnormal_chemical_nociception0.91533155
93MP0008877_abnormal_DNA_methylation0.91070485
94MP0000569_abnormal_digit_pigmentation0.90479342
95MP0001970_abnormal_pain_threshold0.90169252
96MP0003329_amyloid_beta_deposits0.89714692
97MP0004957_abnormal_blastocyst_morpholog0.86370356
98MP0004270_analgesia0.85624296
99MP0002277_abnormal_respiratory_mucosa0.85221535
100MP0001501_abnormal_sleep_pattern0.84605648
101MP0008872_abnormal_physiological_respon0.84353810
102MP0000858_altered_metastatic_potential0.83972674
103MP0002733_abnormal_thermal_nociception0.83549276
104MP0001905_abnormal_dopamine_level0.83443719
105MP0003690_abnormal_glial_cell0.81515914
106MP0004924_abnormal_behavior0.81020121
107MP0005386_behavior/neurological_phenoty0.81020121
108MP0003879_abnormal_hair_cell0.79982007
109MP0000313_abnormal_cell_death0.77947398
110MP0008058_abnormal_DNA_repair0.76878037
111MP0010307_abnormal_tumor_latency0.76279876
112MP0002933_joint_inflammation0.76049667
113MP0001663_abnormal_digestive_system0.75362227
114MP0001853_heart_inflammation0.74547867
115MP0002083_premature_death0.74301075
116MP0006082_CNS_inflammation0.74297931
117MP0002928_abnormal_bile_duct0.68689261
118MP0003075_altered_response_to0.65723200
119MP0003828_pulmonary_edema0.65409534
120MP0002693_abnormal_pancreas_physiology0.60965857
121MP0000604_amyloidosis0.60846660
122MP0004130_abnormal_muscle_cell0.60376916
123MP0002998_abnormal_bone_remodeling0.59615975
124MP0005083_abnormal_biliary_tract0.58769308
125MP0009763_increased_sensitivity_to0.58218243
126MP0009765_abnormal_xenobiotic_induced0.57469512
127MP0001348_abnormal_lacrimal_gland0.57321745
128MP0005535_abnormal_body_temperature0.55594495
129MP0005166_decreased_susceptibility_to0.54878599
130MP0002653_abnormal_ependyma_morphology0.53861712
131MP0002009_preneoplasia0.52984163
132MP0004883_abnormal_blood_vessel0.52735494
133MP0003045_fibrosis0.51382523
134MP0006035_abnormal_mitochondrial_morpho0.49769673
135MP0005058_abnormal_lysosome_morphology0.48730906
136MP0005377_hearing/vestibular/ear_phenot0.48461633

Predicted human phenotypes

RankGene SetZ-score
1Panhypogammaglobulinemia (HP:0003139)4.77351079
2Chronic otitis media (HP:0000389)4.60749566
3Agammaglobulinemia (HP:0004432)4.55471981
4Abnormality of macrophages (HP:0004311)4.35657700
5B lymphocytopenia (HP:0010976)4.07267658
6Abnormality of B cell number (HP:0010975)4.07267658
7Recurrent viral infections (HP:0004429)4.06759128
8Recurrent bronchitis (HP:0002837)4.04163858
9Orchitis (HP:0100796)4.03435816
10Optic neuritis (HP:0100653)3.92517586
11Retrobulbar optic neuritis (HP:0100654)3.92517586
12Cellulitis (HP:0100658)3.87819828
13Papilloma (HP:0012740)3.82503945
14Verrucae (HP:0200043)3.82503945
15IgM deficiency (HP:0002850)3.78270900
16T lymphocytopenia (HP:0005403)3.77899050
17Abnormal delayed hypersensitivity skin test (HP:0002963)3.76438998
18Recurrent gram-negative bacterial infections (HP:0005420)3.60786841
19Thyroiditis (HP:0100646)3.54461690
20Recurrent fungal infections (HP:0002841)3.50131993
21Abnormality of T cell number (HP:0011839)3.49237713
22Gastrointestinal infarctions (HP:0005244)3.42820148
23Meningitis (HP:0001287)3.42470303
24Abnormality of T cells (HP:0002843)3.23595455
25Papilledema (HP:0001085)3.17804290
26Gastrointestinal inflammation (HP:0004386)3.13532085
27Recurrent cutaneous fungal infections (HP:0011370)3.12371713
28Chronic mucocutaneous candidiasis (HP:0002728)3.12371713
29Spontaneous hematomas (HP:0007420)3.12134564
30Severe combined immunodeficiency (HP:0004430)3.09323055
31Chronic sinusitis (HP:0011109)3.03014208
32Hypochromic anemia (HP:0001931)3.02650830
33Urticaria (HP:0001025)3.02226895
34Inflammation of the large intestine (HP:0002037)3.01122828
35Hypochromic microcytic anemia (HP:0004840)3.00356747
36Acute lymphatic leukemia (HP:0006721)2.99539188
37Increased IgM level (HP:0003496)2.97029653
38Abnormality of the fingertips (HP:0001211)2.89769270
39Combined immunodeficiency (HP:0005387)2.84405986
40Elevated erythrocyte sedimentation rate (HP:0003565)2.84320672
41Nasal polyposis (HP:0100582)2.83815606
42Keratoconjunctivitis sicca (HP:0001097)2.79371795
43Epistaxis (HP:0000421)2.77404314
44Colitis (HP:0002583)2.75007650
45IgG deficiency (HP:0004315)2.72795885
46Episodic fever (HP:0001954)2.72064613
47Myokymia (HP:0002411)2.70484204
48Abnormal number of erythroid precursors (HP:0012131)2.66988312
49Keratoconjunctivitis (HP:0001096)2.66413311
50Abnormality of cells of the erythroid lineage (HP:0012130)2.66262005
51Hyperacusis (HP:0010780)2.65838607
52Thrombocytosis (HP:0001894)2.65733237
53Basal cell carcinoma (HP:0002671)2.62542763
54Abnormality of T cell physiology (HP:0011840)2.59059883
55Gingivitis (HP:0000230)2.58433351
56Lymphopenia (HP:0001888)2.55736300
57Hemoptysis (HP:0002105)2.54812203
58Abnormality of cells of the lymphoid lineage (HP:0012140)2.51536198
59Pulmonary infiltrates (HP:0002113)2.48839178
60Increased IgE level (HP:0003212)2.46145380
61Prolonged bleeding time (HP:0003010)2.41610008
62Visual hallucinations (HP:0002367)2.34747057
63Gastrointestinal stroma tumor (HP:0100723)2.31564898
64Hypoplasia of the thymus (HP:0000778)2.29058197
65Pulmonary embolism (HP:0002204)2.27503738
66Autoimmune hemolytic anemia (HP:0001890)2.27277552
67Recurrent sinusitis (HP:0011108)2.27200664
68Abnormality of the nasal mucosa (HP:0000433)2.26124482
69Focal motor seizures (HP:0011153)2.25348105
70Gingival bleeding (HP:0000225)2.24802516
71Hypergammaglobulinemia (HP:0010702)2.24223380
72Myositis (HP:0100614)2.22620821
73Insomnia (HP:0100785)2.21570851
74Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.21165593
75Poikiloderma (HP:0001029)2.20616786
76Lymphoma (HP:0002665)2.19950558
77Recurrent abscess formation (HP:0002722)2.18802561
78Arterial thrombosis (HP:0004420)2.16474564
79Sepsis (HP:0100806)2.15274864
80Anorexia (HP:0002039)2.15074739
81Slow saccadic eye movements (HP:0000514)2.14231640
82Viral hepatitis (HP:0006562)2.13025829
83Abnormality of the heme biosynthetic pathway (HP:0010472)2.10811102
84Supranuclear gaze palsy (HP:0000605)2.10053270
85Eosinophilia (HP:0001880)2.09680995
86Pointed chin (HP:0000307)2.09451034
87Aplasia/Hypoplasia of the thymus (HP:0010515)2.09292218
88Bronchitis (HP:0012387)2.09035228
89Microcytic anemia (HP:0001935)2.08611556
90Abnormality of eosinophils (HP:0001879)2.05793235
91Mediastinal lymphadenopathy (HP:0100721)2.04456185
92Focal seizures (HP:0007359)2.03518204
93Recurrent skin infections (HP:0001581)2.03500033
94Chronic obstructive pulmonary disease (HP:0006510)2.03477322
95Obstructive lung disease (HP:0006536)2.03477322
96Eczematoid dermatitis (HP:0000976)1.99891432
97Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.98988839
98Stomatitis (HP:0010280)1.98769697
99Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.97661086
100Abnormality of the pleura (HP:0002103)1.97174888
101Skin rash (HP:0000988)1.95133228
102Osteomyelitis (HP:0002754)1.95047717
103Vasculitis (HP:0002633)1.95019710
104Acute hepatic failure (HP:0006554)1.93579816
105Chest pain (HP:0100749)1.93223776
106Urinary urgency (HP:0000012)1.92552346
107Granulocytopenia (HP:0001913)1.91888550
108Abnormality of oral frenula (HP:0000190)1.90535585
109Reticulocytopenia (HP:0001896)1.88480546
110Recurrent bacterial skin infections (HP:0005406)1.88464802
111Abnormality of binocular vision (HP:0011514)1.87915432
112Diplopia (HP:0000651)1.87915432
113Absent rod-and cone-mediated responses on ERG (HP:0007688)1.85530601
114Increased cerebral lipofuscin (HP:0011813)1.85333837
115Annular pancreas (HP:0001734)1.85320094
116Impaired smooth pursuit (HP:0007772)1.84735077
117Truncal ataxia (HP:0002078)1.82730625
118Emphysema (HP:0002097)1.82645777
119Purpura (HP:0000979)1.81359277
120Petechiae (HP:0000967)1.81301713
121Recurrent otitis media (HP:0000403)1.80953925
122Increased neuronal autofluorescent lipopigment (HP:0002074)1.80840720
123Hypertensive crisis (HP:0100735)1.80268976
124Amyotrophic lateral sclerosis (HP:0007354)1.79237514
125Amaurosis fugax (HP:0100576)1.78446892
126Poor eye contact (HP:0000817)1.78005602
127Skin ulcer (HP:0200042)1.77659751
128Encephalitis (HP:0002383)1.77538456
129IgA deficiency (HP:0002720)1.76936893
130Prominent nose (HP:0000448)1.72518425
131Vertebral arch anomaly (HP:0008438)1.71921236
132Stereotypic behavior (HP:0000733)1.71906984
133Spastic gait (HP:0002064)1.70233195
134Abnormality of DNA repair (HP:0003254)1.69473702
135Leukocytosis (HP:0001974)1.69445401
136Hemiplegia (HP:0002301)1.68403121
137Ankle clonus (HP:0011448)1.67194593
138Large eyes (HP:0001090)1.64627319
139Cutaneous melanoma (HP:0012056)1.64483377
140Myelodysplasia (HP:0002863)1.64280564
141Pustule (HP:0200039)1.63638936

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K14.76719636
2EEF2K4.15816833
3MAP3K103.65868062
4SIK22.75913757
5PRPF4B2.67329086
6GRK62.64756280
7FES2.50662775
8ERN12.44004123
9SYK2.06834366
10RIPK41.96398186
11TAOK31.95134853
12PKN21.85204107
13MAP3K131.74390047
14BTK1.72840033
15CDK191.70852052
16TXK1.70224317
17KIT1.62746123
18TNK21.61810031
19CLK11.58010233
20ZAP701.48519406
21JAK31.46263556
22EPHA41.46076681
23MAP3K91.45891634
24CDC71.41769454
25NEK21.37497591
26TAOK11.34635054
27CSF1R1.32456578
28DAPK11.32111350
29HCK1.31885665
30TRIB31.30467712
31SCYL21.27595272
32STK101.27390728
33MAP3K141.22801267
34NTRK21.21507949
35TYK21.21260865
36ITK1.20937636
37MARK21.20044281
38TESK21.19251385
39ALK1.17145149
40FGR1.13624469
41PRKCH1.13493149
42MAP3K71.11643680
43LCK1.11221302
44BLK1.10862365
45MARK31.10388790
46LRRK21.06215313
47IKBKE1.05506164
48NTRK31.03717689
49BMPR21.01056334
50MAP3K10.96209380
51UHMK10.95806958
52RAF10.94521572
53CAMKK10.94015476
54CDK40.93986362
55TNIK0.92541469
56SMG10.91063471
57MINK10.90752113
58MAP3K120.89972221
59DAPK20.89295153
60TEC0.87542218
61RPS6KB20.87191866
62IKBKB0.84649708
63KSR20.82965773
64PRKD20.80326284
65LYN0.79846888
66HIPK20.79557166
67MAP3K40.76180675
68CAMKK20.74087632
69TBK10.70887108
70BRSK10.70633565
71CDK50.69740437
72PDK10.68722122
73JAK10.68290542
74PDPK10.66864235
75TAOK20.66123888
76CDK120.65016833
77MAPK130.64129909
78MAPK40.63865595
79MARK10.63512786
80PIM10.60722277
81MAP3K30.60418817
82FLT30.59942573
83CAMK10.58583496
84STK110.57263902
85CDK11A0.56655533
86CCNB10.56403527
87MAPK110.55862124
88CDK150.54793839
89TYRO30.54156024
90YES10.54055346
91PRKCQ0.52693007
92CDK180.52205802
93ATR0.51688597
94MAPK120.51502601
95SIK10.51259270
96PAK60.51250644
97JAK20.51099829
98MAPK70.50835676
99MAP2K40.50692123
100SIK30.50324345
101PTK60.49060732
102PTK2B0.48946825
103MAP3K110.47932281
104FYN0.46237812
105RET0.44835958
106MAP3K60.44160692
107CSK0.42949928
108IRAK20.40392612
109DYRK1B0.40197681
110IRAK10.40055845
111MATK0.39625906
112CAMK40.39575279
113CDK140.39522795
114PASK0.38695691
115PRKCZ0.38400393
116CDC42BPA0.37958658
117RPS6KL10.37703922
118RPS6KC10.37703922
119STK40.37011743
120CDK20.34330456
121CHEK10.34268587
122MAP3K80.34003724
123MAP2K60.33926690
124RPS6KA60.33750953
125FGFR30.32381238
126EPHB10.32039340
127IRAK40.31864912
128BRD40.31838723
129MAP2K20.31505649
130MAP2K30.29634125
131ICK0.29564104
132NLK0.29256925
133KSR10.29159896
134RPS6KA20.28517393
135SGK30.28406611
136FGFR40.27368814

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053403.87278173
2Graft-versus-host disease_Homo sapiens_hsa053322.62480648
3Autoimmune thyroid disease_Homo sapiens_hsa053202.53324847
4B cell receptor signaling pathway_Homo sapiens_hsa046622.50461844
5DNA replication_Homo sapiens_hsa030302.44286257
6Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.01828128
7T cell receptor signaling pathway_Homo sapiens_hsa046601.99762745
8Staphylococcus aureus infection_Homo sapiens_hsa051501.91924485
9Olfactory transduction_Homo sapiens_hsa047401.84617853
10Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.80607287
11Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.77266453
12Mismatch repair_Homo sapiens_hsa034301.69842456
13Base excision repair_Homo sapiens_hsa034101.55767964
14Asthma_Homo sapiens_hsa053101.55749629
15Viral myocarditis_Homo sapiens_hsa054161.49964504
16Long-term potentiation_Homo sapiens_hsa047201.48615370
17Morphine addiction_Homo sapiens_hsa050321.45465900
18Non-small cell lung cancer_Homo sapiens_hsa052231.42128401
19Non-homologous end-joining_Homo sapiens_hsa034501.40781577
20Ribosome_Homo sapiens_hsa030101.32493462
21Nicotine addiction_Homo sapiens_hsa050331.28347434
22Osteoclast differentiation_Homo sapiens_hsa043801.25909173
23Chemokine signaling pathway_Homo sapiens_hsa040621.25255707
24Acute myeloid leukemia_Homo sapiens_hsa052211.25240116
25Hematopoietic cell lineage_Homo sapiens_hsa046401.24956081
26Measles_Homo sapiens_hsa051621.22754502
27Toxoplasmosis_Homo sapiens_hsa051451.21863273
28Chronic myeloid leukemia_Homo sapiens_hsa052201.20282661
29Neurotrophin signaling pathway_Homo sapiens_hsa047221.18307426
30Intestinal immune network for IgA production_Homo sapiens_hsa046721.17816345
31Glutamatergic synapse_Homo sapiens_hsa047241.17765094
32Spliceosome_Homo sapiens_hsa030401.16645584
33VEGF signaling pathway_Homo sapiens_hsa043701.16016987
34Circadian entrainment_Homo sapiens_hsa047131.13383895
35Synaptic vesicle cycle_Homo sapiens_hsa047211.10577869
36Dopaminergic synapse_Homo sapiens_hsa047281.10556684
37NF-kappa B signaling pathway_Homo sapiens_hsa040641.10326642
38Phosphatidylinositol signaling system_Homo sapiens_hsa040701.07297652
39Antigen processing and presentation_Homo sapiens_hsa046121.07188306
40Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.05338994
41Leishmaniasis_Homo sapiens_hsa051401.05329125
42Glioma_Homo sapiens_hsa052141.05293600
43Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.04103185
44Platelet activation_Homo sapiens_hsa046111.02188837
45Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.00612915
46Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.00524586
47Colorectal cancer_Homo sapiens_hsa052100.99210571
48Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.99075889
49Cholinergic synapse_Homo sapiens_hsa047250.98863012
50Amphetamine addiction_Homo sapiens_hsa050310.97345882
51Malaria_Homo sapiens_hsa051440.97234936
52Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.96659506
53Phagosome_Homo sapiens_hsa041450.95755344
54GABAergic synapse_Homo sapiens_hsa047270.94701569
55Aldosterone synthesis and secretion_Homo sapiens_hsa049250.94027089
56Homologous recombination_Homo sapiens_hsa034400.92193388
57Hepatitis B_Homo sapiens_hsa051610.91857173
58Oxytocin signaling pathway_Homo sapiens_hsa049210.91507294
59Herpes simplex infection_Homo sapiens_hsa051680.90522024
60Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.89565905
61African trypanosomiasis_Homo sapiens_hsa051430.89154527
62Shigellosis_Homo sapiens_hsa051310.88912390
63Salivary secretion_Homo sapiens_hsa049700.88651562
64Jak-STAT signaling pathway_Homo sapiens_hsa046300.88516421
65Gastric acid secretion_Homo sapiens_hsa049710.87636396
66SNARE interactions in vesicular transport_Homo sapiens_hsa041300.86374305
67Pancreatic cancer_Homo sapiens_hsa052120.86066475
68TNF signaling pathway_Homo sapiens_hsa046680.85466605
69Cell cycle_Homo sapiens_hsa041100.85271762
70Legionellosis_Homo sapiens_hsa051340.85185349
71Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.84977221
72Alcoholism_Homo sapiens_hsa050340.84933397
73Oocyte meiosis_Homo sapiens_hsa041140.84759780
74Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.83968736
75mRNA surveillance pathway_Homo sapiens_hsa030150.83964556
76Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.82644967
77ErbB signaling pathway_Homo sapiens_hsa040120.81249272
78Phospholipase D signaling pathway_Homo sapiens_hsa040720.79215606
79Hepatitis C_Homo sapiens_hsa051600.79171098
80Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.79113652
81Nucleotide excision repair_Homo sapiens_hsa034200.79104552
82Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.78991456
83Rheumatoid arthritis_Homo sapiens_hsa053230.76405143
84HTLV-I infection_Homo sapiens_hsa051660.75673294
85mTOR signaling pathway_Homo sapiens_hsa041500.75626877
86RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.74688345
87Regulation of autophagy_Homo sapiens_hsa041400.74353704
88MAPK signaling pathway_Homo sapiens_hsa040100.73974258
89Notch signaling pathway_Homo sapiens_hsa043300.72585702
90Epstein-Barr virus infection_Homo sapiens_hsa051690.71836189
91Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.71082743
92Long-term depression_Homo sapiens_hsa047300.70992068
93GnRH signaling pathway_Homo sapiens_hsa049120.70610427
94Transcriptional misregulation in cancer_Homo sapiens_hsa052020.68481899
95Viral carcinogenesis_Homo sapiens_hsa052030.68355716
96Choline metabolism in cancer_Homo sapiens_hsa052310.67992119
97Renin secretion_Homo sapiens_hsa049240.67687956
98Cocaine addiction_Homo sapiens_hsa050300.66967178
99Endocytosis_Homo sapiens_hsa041440.66457559
100Calcium signaling pathway_Homo sapiens_hsa040200.66060768
101Glycerophospholipid metabolism_Homo sapiens_hsa005640.65931066
102Thyroid hormone signaling pathway_Homo sapiens_hsa049190.65773867
103Estrogen signaling pathway_Homo sapiens_hsa049150.64373607
104Tuberculosis_Homo sapiens_hsa051520.63119886
105Endometrial cancer_Homo sapiens_hsa052130.62922558
106Carbohydrate digestion and absorption_Homo sapiens_hsa049730.62243363
107Apoptosis_Homo sapiens_hsa042100.62075955
108Sphingolipid signaling pathway_Homo sapiens_hsa040710.61740722
109Renal cell carcinoma_Homo sapiens_hsa052110.61639197
110Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.60923733
111Inositol phosphate metabolism_Homo sapiens_hsa005620.60794940
112Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.60634788
113NOD-like receptor signaling pathway_Homo sapiens_hsa046210.60374379
114Influenza A_Homo sapiens_hsa051640.59351746
115Allograft rejection_Homo sapiens_hsa053300.58447801
116Gap junction_Homo sapiens_hsa045400.57011359
117Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.56604388
118Leukocyte transendothelial migration_Homo sapiens_hsa046700.56478757
119Toll-like receptor signaling pathway_Homo sapiens_hsa046200.56269600
120Prolactin signaling pathway_Homo sapiens_hsa049170.56217494
121Salmonella infection_Homo sapiens_hsa051320.55551418
122Type II diabetes mellitus_Homo sapiens_hsa049300.55206960
123Other glycan degradation_Homo sapiens_hsa005110.54800039
124Type I diabetes mellitus_Homo sapiens_hsa049400.54502828
125Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.48339450
126FoxO signaling pathway_Homo sapiens_hsa040680.46388955
127Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.45445275
128HIF-1 signaling pathway_Homo sapiens_hsa040660.41835539
129Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.40314027
130Pertussis_Homo sapiens_hsa051330.39984518
131Ras signaling pathway_Homo sapiens_hsa040140.39337185
132Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.39112208
133Rap1 signaling pathway_Homo sapiens_hsa040150.38424032

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