FCHO2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.58498914
2regulation of interferon-beta biosynthetic process (GO:0045357)4.18834603
3modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.11814672
4positive regulation by organism of defense response of other organism involved in symbiotic interact4.11814672
5modulation by symbiont of host immune response (GO:0052553)4.11814672
6positive regulation by symbiont of host defense response (GO:0052509)4.11814672
7modulation by symbiont of host defense response (GO:0052031)4.11814672
8modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.11814672
9oligosaccharide catabolic process (GO:0009313)4.01235140
10negative regulation of complement activation (GO:0045916)3.84473471
11glycosphingolipid catabolic process (GO:0046479)3.68445190
12negative regulation of protein activation cascade (GO:2000258)3.48691616
13growth hormone receptor signaling pathway (GO:0060396)3.39365444
14glycolipid catabolic process (GO:0019377)3.30716518
15macrophage activation involved in immune response (GO:0002281)3.27168857
16macroautophagy (GO:0016236)3.26593907
17neutrophil activation involved in immune response (GO:0002283)3.14565632
18positive regulation of receptor recycling (GO:0001921)3.13761455
19ceramide catabolic process (GO:0046514)3.10534994
20protein targeting to lysosome (GO:0006622)3.03607886
21establishment of protein localization to vacuole (GO:0072666)3.03607886
22protein targeting to vacuole (GO:0006623)3.03607886
23keratan sulfate catabolic process (GO:0042340)3.03215080
24positive regulation of interferon-alpha production (GO:0032727)2.99620138
25microglial cell activation (GO:0001774)2.94385696
26negative regulation of humoral immune response (GO:0002921)2.92063603
27cellular response to growth hormone stimulus (GO:0071378)2.89523315
28detection of external biotic stimulus (GO:0098581)2.88961321
29early endosome to late endosome transport (GO:0045022)2.81087744
30amino sugar catabolic process (GO:0046348)2.80557256
31regulation of interferon-alpha production (GO:0032647)2.80221334
32cellular response to ethanol (GO:0071361)2.76723869
33I-kappaB phosphorylation (GO:0007252)2.76398365
34positive regulation of p38MAPK cascade (GO:1900745)2.75161617
35response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.74615566
36response to host immune response (GO:0052572)2.74615566
37definitive hemopoiesis (GO:0060216)2.73177048
38regulation of macrophage chemotaxis (GO:0010758)2.71690879
39surfactant homeostasis (GO:0043129)2.67948069
40negative regulation of macrophage derived foam cell differentiation (GO:0010745)2.67464132
41response to lipoprotein particle (GO:0055094)2.61175356
42interleukin-6-mediated signaling pathway (GO:0070102)2.59878609
43response to muramyl dipeptide (GO:0032495)2.57355946
44response to host (GO:0075136)2.57090913
45response to host defenses (GO:0052200)2.57090913
46response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.57090913
47adhesion of symbiont to host (GO:0044406)2.54432982
48detection of other organism (GO:0098543)2.52129400
49positive regulation of cellular amide metabolic process (GO:0034250)2.52005523
50negative regulation of lipid storage (GO:0010888)2.51949224
51regulation of integrin-mediated signaling pathway (GO:2001044)2.51939811
52regulation of mononuclear cell migration (GO:0071675)2.51884383
53import into cell (GO:0098657)2.51580400
54regulation of cholesterol storage (GO:0010885)2.51004602
55negative regulation of interleukin-17 production (GO:0032700)2.50352747
56adhesion of symbiont to host cell (GO:0044650)2.49570956
57virion attachment to host cell (GO:0019062)2.49570956
58response to thyroid hormone (GO:0097066)2.45179426
59negative regulation of interleukin-12 production (GO:0032695)2.44968834
60neutrophil activation (GO:0042119)2.42967826
61positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.40938041
62macrophage activation (GO:0042116)2.40627784
63production of molecular mediator involved in inflammatory response (GO:0002532)2.38245728
64cellular extravasation (GO:0045123)2.37809818
65cellular response to thyroid hormone stimulus (GO:0097067)2.35178082
66N-acetylneuraminate metabolic process (GO:0006054)2.33652316
67neutrophil mediated immunity (GO:0002446)2.32418849
68lung lobe morphogenesis (GO:0060463)2.32396696
69response to laminar fluid shear stress (GO:0034616)2.32386289
70cell adhesion mediated by integrin (GO:0033627)2.32365749
71positive regulation of monocyte chemotaxis (GO:0090026)2.32312988
72angiotensin maturation (GO:0002003)2.32130999
73vascular endothelial growth factor signaling pathway (GO:0038084)2.31106018
74detection of biotic stimulus (GO:0009595)2.31089586
75cellular response to exogenous dsRNA (GO:0071360)2.31055665
76barbed-end actin filament capping (GO:0051016)2.31002051
77T-helper 1 type immune response (GO:0042088)2.30528686
78phospholipid efflux (GO:0033700)2.30371023
79granulocyte activation (GO:0036230)2.28670798
80phagocytosis, recognition (GO:0006910)2.28091876
81toxin transport (GO:1901998)2.27873388
82lipoprotein transport (GO:0042953)2.27098948
83positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.26937741
84positive regulation of sterol transport (GO:0032373)2.26689010
85positive regulation of smooth muscle cell migration (GO:0014911)2.24270399
86blood vessel maturation (GO:0001955)2.23516371
87hypotonic response (GO:0006971)2.22562835
88phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.22064597
89apoptotic cell clearance (GO:0043277)2.21781058
90platelet-derived growth factor receptor signaling pathway (GO:0048008)2.21423130
91regulation of monocyte chemotaxis (GO:0090025)2.21206175
92response to peptidoglycan (GO:0032494)2.21114316
93retina vasculature morphogenesis in camera-type eye (GO:0061299)2.20814050
94sphingolipid catabolic process (GO:0030149)2.20255492
95nerve growth factor signaling pathway (GO:0038180)2.20219515
96viral entry into host cell (GO:0046718)2.20063803
97membrane lipid catabolic process (GO:0046466)2.19663784
98superoxide anion generation (GO:0042554)2.19633152
99embryonic retina morphogenesis in camera-type eye (GO:0060059)2.19204166
100regulation of nitric-oxide synthase biosynthetic process (GO:0051769)2.18959120
101skin morphogenesis (GO:0043589)2.18590673
102positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.18090860
103lipid translocation (GO:0034204)2.17843715
104phospholipid translocation (GO:0045332)2.17843715
105positive regulation of interferon-beta production (GO:0032728)2.17797099
106negative regulation of granulocyte differentiation (GO:0030853)2.17678925
107positive regulation of vasculogenesis (GO:2001214)2.17086964
108regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.16618575
109response to fluid shear stress (GO:0034405)2.16270654
110regulation of interleukin-12 biosynthetic process (GO:0045075)2.14820163
111positive regulation of leukocyte degranulation (GO:0043302)2.14672873
112phospholipid homeostasis (GO:0055091)2.14316943
113positive regulation of toll-like receptor signaling pathway (GO:0034123)2.13463772
114positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.13237659
115protein targeting to Golgi (GO:0000042)2.12923569
116protein localization to endosome (GO:0036010)2.12074099
117positive regulation of coagulation (GO:0050820)2.11371589
118intracellular lipid transport (GO:0032365)2.11167807
119lymph vessel development (GO:0001945)2.11056813
120ovulation from ovarian follicle (GO:0001542)2.10711237
121lung vasculature development (GO:0060426)2.10687929
122establishment of protein localization to Golgi (GO:0072600)2.10414451
123endothelium development (GO:0003158)2.10370174
124negative regulation of protein localization to plasma membrane (GO:1903077)2.09925893
125retrograde transport, vesicle recycling within Golgi (GO:0000301)2.09803353
126positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.09794770
127prostate gland growth (GO:0060736)2.08945286
128regulation of macrophage cytokine production (GO:0010935)2.08464093
129antigen processing and presentation of endogenous antigen (GO:0019883)2.08383534
130positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.08238331
131positive regulation of T cell chemotaxis (GO:0010820)2.07947915
132regulation of T cell chemotaxis (GO:0010819)2.07947915
133cholesterol efflux (GO:0033344)2.07091404
134peptidyl-glutamic acid carboxylation (GO:0017187)2.06409228
135protein carboxylation (GO:0018214)2.06409228
136myeloid cell activation involved in immune response (GO:0002275)2.06042773
137establishment of endothelial barrier (GO:0061028)2.04951877
138positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.04801667
139peptide catabolic process (GO:0043171)2.03971607
140regulation of vasculogenesis (GO:2001212)2.03537911
141antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.03256232
142antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.03256232
143glomerular filtration (GO:0003094)2.02244646
144immunoglobulin mediated immune response (GO:0016064)2.02219640
145response to type I interferon (GO:0034340)2.00627981
146JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.00389072
147phagocytosis, engulfment (GO:0006911)1.99764374
148pathway-restricted SMAD protein phosphorylation (GO:0060389)1.99094075
149interleukin-1-mediated signaling pathway (GO:0070498)1.98254520
150positive regulation of cholesterol efflux (GO:0010875)1.98252582
151low-density lipoprotein particle clearance (GO:0034383)1.98177076
152regulation of macrophage derived foam cell differentiation (GO:0010743)1.98101460
153iron ion import (GO:0097286)1.98023373
154respiratory burst (GO:0045730)1.97951739
155detection of molecule of bacterial origin (GO:0032490)1.96661067
156Notch signaling involved in heart development (GO:0061314)1.96561755
157fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)1.95913728
158cellular response to type I interferon (GO:0071357)1.94472982
159type I interferon signaling pathway (GO:0060337)1.94472982
160leukocyte tethering or rolling (GO:0050901)1.94193687
161positive regulation of cholesterol transport (GO:0032376)1.93614935

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human3.88400007
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.36585476
3IRF8_22096565_ChIP-ChIP_GC-B_Human3.29763137
4SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.83219430
5IRF8_21731497_ChIP-ChIP_J774_Mouse2.79808378
6* IRF8_27001747_Chip-Seq_BMDM_Mouse2.71658691
7* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.69012846
8STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.43310245
9NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.43229691
10IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.37286899
11GATA2_21666600_ChIP-Seq_HMVEC_Human2.19404159
12GATA1_22025678_ChIP-Seq_K562_Human2.15934958
13SCL_19346495_ChIP-Seq_HPC-7_Human2.09693415
14NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.05459861
15TRIM28_21343339_ChIP-Seq_HEK293_Human2.05380836
16STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.04853573
17LXR_22158963_ChIP-Seq_LIVER_Mouse1.98421916
18ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.98040363
19POU3F2_20337985_ChIP-ChIP_501MEL_Human1.96370047
20STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.95467758
21RUNX_20019798_ChIP-Seq_JUKART_Human1.92241418
22CDX2_19796622_ChIP-Seq_MESCs_Mouse1.88688818
23MYB_21317192_ChIP-Seq_ERMYB_Mouse1.85932036
24CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.85546736
25MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.84054197
26RXR_22158963_ChIP-Seq_LIVER_Mouse1.78827364
27RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.78460209
28VDR_24787735_ChIP-Seq_THP-1_Human1.72641821
29SMAD_19615063_ChIP-ChIP_OVARY_Human1.71251203
30TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.70444577
31GBX2_23144817_ChIP-Seq_PC3_Human1.69671618
32STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.68426257
33CLOCK_20551151_ChIP-Seq_293T_Human1.67689137
34ESR1_21235772_ChIP-Seq_MCF-7_Human1.67373090
35FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.62248511
36TP63_17297297_ChIP-ChIP_HaCaT_Human1.61731165
37ZFP57_27257070_Chip-Seq_ESCs_Mouse1.59942232
38ZNF217_24962896_ChIP-Seq_MCF-7_Human1.58657775
39CJUN_26792858_Chip-Seq_BT549_Human1.56115152
40SALL4_18804426_ChIP-ChIP_XEN_Mouse1.55838178
41FOXO3_23340844_ChIP-Seq_DLD1_Human1.54676988
42CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.47652145
43PPARA_22158963_ChIP-Seq_LIVER_Mouse1.46047325
44ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.45851621
45PPAR_26484153_Chip-Seq_NCI-H1993_Human1.42724221
46GATA1_19941826_ChIP-Seq_K562_Human1.42433360
47NRF2_20460467_ChIP-Seq_MEFs_Mouse1.41871834
48NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.41871834
49EGR1_23403033_ChIP-Seq_LIVER_Mouse1.38581203
50PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.38210975
51* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.35529804
52SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.34889310
53* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.34631789
54IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.34160082
55OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.34002845
56EGR1_19374776_ChIP-ChIP_THP-1_Human1.33088953
57SALL1_21062744_ChIP-ChIP_HESCs_Human1.32454984
58SMAD4_21799915_ChIP-Seq_A2780_Human1.32161797
59NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.32120989
60* PU_27001747_Chip-Seq_BMDM_Mouse1.26366682
61WT1_19549856_ChIP-ChIP_CCG9911_Human1.26161634
62TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.25872320
63BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.25584892
64* SOX2_20726797_ChIP-Seq_SW620_Human1.25389910
65* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.25357969
66ESR1_20079471_ChIP-ChIP_T-47D_Human1.24419641
67EZH2_27294783_Chip-Seq_NPCs_Mouse1.23447658
68PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.23119169
69VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.22934193
70NR3C1_21868756_ChIP-Seq_MCF10A_Human1.21910173
71SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.21642991
72GATA2_19941826_ChIP-Seq_K562_Human1.21362538
73* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.20895621
74BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.20852715
75ESR2_21235772_ChIP-Seq_MCF-7_Human1.20610894
76TP53_16413492_ChIP-PET_HCT116_Human1.20193917
77ARNT_22903824_ChIP-Seq_MCF-7_Human1.18545627
78GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17863463
79NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.17095790
80CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.16660869
81THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.16368657
82P300_19829295_ChIP-Seq_ESCs_Human1.16222600
83SOX2_27498859_Chip-Seq_STOMACH_Mouse1.16069346
84MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.15740519
85CDX2_22108803_ChIP-Seq_LS180_Human1.15001018
86ER_23166858_ChIP-Seq_MCF-7_Human1.14875069
87STAT3_23295773_ChIP-Seq_U87_Human1.14189901
88NANOG_18555785_Chip-Seq_ESCs_Mouse1.12718523
89TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.12689098
90GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.10374049
91SUZ12_27294783_Chip-Seq_NPCs_Mouse1.09840256
92ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.09296650
93PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.08495480
94AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.07757227
95FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.07406765
96SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.06136180
97SMAD3_21741376_ChIP-Seq_EPCs_Human1.05130485
98* FOXA2_19822575_ChIP-Seq_HepG2_Human1.04757324
99* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.04733239
100EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.04726577
101E2F1_18555785_Chip-Seq_ESCs_Mouse1.04582892
102NFIB_24661679_ChIP-Seq_LUNG_Mouse1.03966016
103* TP53_18474530_ChIP-ChIP_U2OS_Human1.03814840
104AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.03597774
105SPI1_23127762_ChIP-Seq_K562_Human1.03469136
106* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.03324302
107SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.01980152
108AR_25329375_ChIP-Seq_VCAP_Human1.01973880
109BCAT_22108803_ChIP-Seq_LS180_Human1.01141033
110CMYC_18555785_Chip-Seq_ESCs_Mouse1.00349347
111UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.00111159
112NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.99306499
113* SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.98323759
114* SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.98323759
115CRX_20693478_ChIP-Seq_RETINA_Mouse0.97121627
116* TCF4_23295773_ChIP-Seq_U87_Human0.96795652
117SMAD3_21741376_ChIP-Seq_HESCs_Human0.96528212
118EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.95676673
119CTNNB1_20460455_ChIP-Seq_HCT116_Human0.95274416
120RXR_22108803_ChIP-Seq_LS180_Human0.94266240
121SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.94082663
122* TP63_23658742_ChIP-Seq_EP156T_Human0.93776333
123MYB_26560356_Chip-Seq_TH2_Human0.92811510
124CDX2_20551321_ChIP-Seq_CACO-2_Human0.92797880
125FOXM1_26456572_ChIP-Seq_MCF-7_Human0.92561307
126EP300_21415370_ChIP-Seq_HL-1_Mouse0.92151470
127GATA4_25053715_ChIP-Seq_YYC3_Human0.91501202
128PIAS1_25552417_ChIP-Seq_VCAP_Human0.90977770
129MYB_26560356_Chip-Seq_TH1_Human0.90204308
130VDR_24763502_ChIP-Seq_THP-1_Human0.88819153
131AHR_22903824_ChIP-Seq_MCF-7_Human0.88435210
132STAT4_19710469_ChIP-ChIP_TH1__Mouse0.87796491
133TCF7_22412390_ChIP-Seq_EML_Mouse0.87787908
134SOX9_24532713_ChIP-Seq_HFSC_Mouse0.85399574
135EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.85189959
136* FOXA1_25552417_ChIP-Seq_VCAP_Human0.84432260
137BRD4_25478319_ChIP-Seq_HGPS_Human0.84342152
138GATA1_19941827_ChIP-Seq_MEL_Mouse0.81814216
139GATA3_27048872_Chip-Seq_THYMUS_Human0.80952311
140TCF4_18268006_ChIP-ChIP_LS174T_Human0.80756068
141MAF_26560356_Chip-Seq_TH1_Human0.80232829
142KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.80135191

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003300_gastrointestinal_ulcer2.65860217
2MP0010368_abnormal_lymphatic_system2.53477472
3MP0003191_abnormal_cellular_cholesterol2.50418151
4MP0002138_abnormal_hepatobiliary_system2.48642845
5MP0001835_abnormal_antigen_presentation2.48378017
6MP0001879_abnormal_lymphatic_vessel2.38368889
7MP0005058_abnormal_lysosome_morphology2.35552395
8MP0003724_increased_susceptibility_to2.29909287
9MP0003436_decreased_susceptibility_to2.10932700
10MP0002419_abnormal_innate_immunity1.96636559
11MP0003252_abnormal_bile_duct1.96127246
12MP0005167_abnormal_blood-brain_barrier1.93431811
13MP0009278_abnormal_bone_marrow1.86641430
14MP0002139_abnormal_hepatobiliary_system1.85210187
15MP0002254_reproductive_system_inflammat1.84162778
16MP0005275_abnormal_skin_tensile1.83534203
17MP0005360_urolithiasis1.83082679
18MP0003690_abnormal_glial_cell1.82033705
19MP0003303_peritoneal_inflammation1.81535538
20MP0002166_altered_tumor_susceptibility1.80848074
21MP0002009_preneoplasia1.78237214
22MP0006082_CNS_inflammation1.77541517
23MP0003828_pulmonary_edema1.76619326
24MP0000604_amyloidosis1.73213359
25MP0000569_abnormal_digit_pigmentation1.70190291
26MP0003195_calcinosis1.68086291
27MP0001851_eye_inflammation1.65687449
28MP0005387_immune_system_phenotype1.64322287
29MP0001790_abnormal_immune_system1.64322287
30MP0004264_abnormal_extraembryonic_tissu1.56965673
31MP0005464_abnormal_platelet_physiology1.55202864
32MP0003183_abnormal_peptide_metabolism1.54835920
33MP0005025_abnormal_response_to1.53820793
34MP0005257_abnormal_intraocular_pressure1.52247502
35MP0001533_abnormal_skeleton_physiology1.50903559
36MP0000685_abnormal_immune_system1.50643876
37MP0005000_abnormal_immune_tolerance1.50102669
38MP0005085_abnormal_gallbladder_physiolo1.48047658
39MP0006054_spinal_hemorrhage1.47575755
40MP0009785_altered_susceptibility_to1.45845431
41MP0002928_abnormal_bile_duct1.43924029
42MP0002452_abnormal_antigen_presenting1.41370440
43MP0002148_abnormal_hypersensitivity_rea1.40648452
44MP0009840_abnormal_foam_cell1.39120548
45MP0005397_hematopoietic_system_phenotyp1.38071933
46MP0001545_abnormal_hematopoietic_system1.38071933
47MP0000767_abnormal_smooth_muscle1.35486242
48MP0004272_abnormal_basement_membrane1.33139128
49MP0003045_fibrosis1.32184444
50MP0003705_abnormal_hypodermis_morpholog1.29793139
51MP0004484_altered_response_of1.29656593
52MP0009764_decreased_sensitivity_to1.29631998
53MP0010678_abnormal_skin_adnexa1.29506550
54MP0001800_abnormal_humoral_immune1.29097396
55MP0003448_altered_tumor_morphology1.27993975
56MP0002006_tumorigenesis1.26153431
57MP0002723_abnormal_immune_serum1.25629556
58MP0008438_abnormal_cutaneous_collagen1.23561661
59MP0005671_abnormal_response_to1.22959022
60MP0000427_abnormal_hair_cycle1.22569222
61MP0000343_altered_response_to1.22441865
62MP0000383_abnormal_hair_follicle1.21163846
63MP0004947_skin_inflammation1.19021111
64MP0002998_abnormal_bone_remodeling1.19010931
65MP0002133_abnormal_respiratory_system1.17603579
66MP0005388_respiratory_system_phenotype1.17603579
67MP0001958_emphysema1.17517434
68MP0010155_abnormal_intestine_physiology1.16841803
69MP0010352_gastrointestinal_tract_polyps1.16627433
70MP0004147_increased_porphyrin_level1.16422294
71MP0008004_abnormal_stomach_pH1.16011503
72MP0001845_abnormal_inflammatory_respons1.14202715
73MP0005365_abnormal_bile_salt1.13264174
74MP0001819_abnormal_immune_cell1.12045963
75MP0003172_abnormal_lysosome_physiology1.11321688
76MP0008469_abnormal_protein_level1.10767778
77MP0003075_altered_response_to1.10459048
78MP0004782_abnormal_surfactant_physiolog1.10385178
79MP0002420_abnormal_adaptive_immunity1.10247327
80MP0004019_abnormal_vitamin_homeostasis1.09797606
81MP0002405_respiratory_system_inflammati1.08412282
82MP0000465_gastrointestinal_hemorrhage1.08064100
83MP0002896_abnormal_bone_mineralization1.07612211
84MP0001853_heart_inflammation1.07596048
85MP0003656_abnormal_erythrocyte_physiolo1.07581477
86MP0008875_abnormal_xenobiotic_pharmacok1.06615603
87MP0005310_abnormal_salivary_gland1.06009373
88MP0004510_myositis1.05431113
89MP0001873_stomach_inflammation1.05097694
90MP0005164_abnormal_response_to1.04639780
91MP0003566_abnormal_cell_adhesion1.04074747
92MP0008260_abnormal_autophagy1.02872954
93MP0003943_abnormal_hepatobiliary_system1.02677314
94MP0000249_abnormal_blood_vessel1.01563641
95MP0004808_abnormal_hematopoietic_stem1.01231001
96MP0004883_abnormal_blood_vessel1.00874959
97MP0005023_abnormal_wound_healing0.98603251
98MP0000920_abnormal_myelination0.94867959
99MP0002136_abnormal_kidney_physiology0.94643466
100MP0005595_abnormal_vascular_smooth0.94620216
101MP0003279_aneurysm0.92479761
102MP0000609_abnormal_liver_physiology0.92043979
103MP0009643_abnormal_urine_homeostasis0.91944409
104MP0002332_abnormal_exercise_endurance0.91572392
105MP0003950_abnormal_plasma_membrane0.90580605
106MP0010329_abnormal_lipoprotein_level0.90564287
107MP0002295_abnormal_pulmonary_circulatio0.89960499
108MP0000015_abnormal_ear_pigmentation0.88964108
109MP0002877_abnormal_melanocyte_morpholog0.87817537
110MP0002933_joint_inflammation0.87385187
111MP0004185_abnormal_adipocyte_glucose0.87332845
112MP0009763_increased_sensitivity_to0.86784384
113MP0000371_diluted_coat_color0.86305620
114MP0003453_abnormal_keratinocyte_physiol0.85967483
115MP0005166_decreased_susceptibility_to0.85103973
116MP0001915_intracranial_hemorrhage0.84619097
117MP0010234_abnormal_vibrissa_follicle0.83221608
118MP0004130_abnormal_muscle_cell0.83011115
119MP0000647_abnormal_sebaceous_gland0.82307084
120MP0000858_altered_metastatic_potential0.81478064
121MP0003091_abnormal_cell_migration0.81192609
122MP0005165_increased_susceptibility_to0.80841786
123MP0005409_darkened_coat_color0.80253951
124MP0005174_abnormal_tail_pigmentation0.80033859
125MP0005390_skeleton_phenotype0.79630066
126MP0000733_abnormal_muscle_development0.79509684
127MP0005451_abnormal_body_composition0.78439506
128MP0002971_abnormal_brown_adipose0.77831771
129MP0002168_other_aberrant_phenotype0.76608743
130MP0002128_abnormal_blood_circulation0.76418001
131MP0004043_abnormal_pH_regulation0.76217334

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of liposaccharide metabolism (HP:0010968)6.50115018
2Abnormality of glycosphingolipid metabolism (HP:0004343)6.50115018
3Abnormality of glycolipid metabolism (HP:0010969)6.50115018
4Hematochezia (HP:0002573)4.47112256
5Eczematoid dermatitis (HP:0000976)4.38161811
6Systemic lupus erythematosus (HP:0002725)4.15836045
7Recurrent abscess formation (HP:0002722)4.14418324
8Recurrent bacterial skin infections (HP:0005406)4.05830025
9Spontaneous hematomas (HP:0007420)3.75850559
10Recurrent gram-negative bacterial infections (HP:0005420)3.71069052
11Glomerulonephritis (HP:0000099)3.52700941
12Vacuolated lymphocytes (HP:0001922)3.47372496
13Abnormality of macrophages (HP:0004311)3.35485459
14Myocardial infarction (HP:0001658)3.32022083
15Autoimmune thrombocytopenia (HP:0001973)3.22515717
16Increased cerebral lipofuscin (HP:0011813)3.16819910
17Complement deficiency (HP:0004431)3.14042084
18Axonal loss (HP:0003447)3.08167854
19Increased neuronal autofluorescent lipopigment (HP:0002074)2.90559794
20Esophageal varix (HP:0002040)2.89001961
21Osteolytic defects of the phalanges of the hand (HP:0009771)2.75125688
22Osteolytic defects of the hand bones (HP:0009699)2.75125688
23Mitral stenosis (HP:0001718)2.73690407
24Aortic aneurysm (HP:0004942)2.71656035
25Polycythemia (HP:0001901)2.63730480
26Nephritis (HP:0000123)2.59643641
27Recurrent skin infections (HP:0001581)2.59481834
28Papillary thyroid carcinoma (HP:0002895)2.58314654
29Abnormality of the fingertips (HP:0001211)2.52451308
30Vascular tortuosity (HP:0004948)2.49859635
31Disinhibition (HP:0000734)2.49093313
32Gingival bleeding (HP:0000225)2.45873676
33Neurofibrillary tangles (HP:0002185)2.45239971
34Arterial tortuosity (HP:0005116)2.43960227
35Thick nail (HP:0001805)2.43452942
36Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.40326930
37Spondylolisthesis (HP:0003302)2.38294983
38Periodontitis (HP:0000704)2.33508002
39Gingivitis (HP:0000230)2.32081125
40Dysostosis multiplex (HP:0000943)2.31289117
41Joint hemorrhage (HP:0005261)2.31286677
42Abnormality of the vasculature of the conjunctiva (HP:0008054)2.29068158
43Recurrent fungal infections (HP:0002841)2.27377111
44Right ventricular cardiomyopathy (HP:0011663)2.26136131
45Portal hypertension (HP:0001409)2.25027292
46Abnormality of complement system (HP:0005339)2.24370143
47Cerebral inclusion bodies (HP:0100314)2.17653334
48Hypercholesterolemia (HP:0003124)2.16558035
49Colitis (HP:0002583)2.13433872
50Skin nodule (HP:0200036)2.08874239
51Epidermoid cyst (HP:0200040)2.08712244
52Retinal atrophy (HP:0001105)2.08540949
53Deep venous thrombosis (HP:0002625)2.08522074
54Tubulointerstitial fibrosis (HP:0005576)2.07902827
55Conjugated hyperbilirubinemia (HP:0002908)2.07734754
56Inappropriate behavior (HP:0000719)2.07264444
57Asymmetric septal hypertrophy (HP:0001670)2.05695217
58Abnormality of the hepatic vasculature (HP:0006707)2.05149404
59Conjunctival telangiectasia (HP:0000524)2.02048185
60Mucopolysacchariduria (HP:0008155)2.01252950
61Urinary glycosaminoglycan excretion (HP:0003541)2.01252950
62Retrobulbar optic neuritis (HP:0100654)2.01070560
63Optic neuritis (HP:0100653)2.01070560
64Arterial thrombosis (HP:0004420)1.99987757
65Metaphyseal dysplasia (HP:0100255)1.98870260
66Recurrent viral infections (HP:0004429)1.98366250
67Hyperventilation (HP:0002883)1.97391950
68Abnormality of the periventricular white matter (HP:0002518)1.97130600
69Prostate neoplasm (HP:0100787)1.95026362
70Fair hair (HP:0002286)1.92897270
71Aortic dissection (HP:0002647)1.91555330
72Hydroxyprolinuria (HP:0003080)1.91424040
73Abnormality of proline metabolism (HP:0010907)1.91424040
74Progressive visual loss (HP:0000529)1.91035359
75Abnormality of the lumbar spine (HP:0100712)1.90707083
76Abnormality of mucopolysaccharide metabolism (HP:0011020)1.90233167
77Abnormality of polysaccharide metabolism (HP:0011012)1.90233167
78Abnormality of glycosaminoglycan metabolism (HP:0004371)1.90233167
79Slow saccadic eye movements (HP:0000514)1.89357410
80Pulmonary embolism (HP:0002204)1.89134397
81Epistaxis (HP:0000421)1.88850480
82Orchitis (HP:0100796)1.88721854
83Keratoconjunctivitis (HP:0001096)1.88029536
84Hypochromic microcytic anemia (HP:0004840)1.87949503
85Cerebral aneurysm (HP:0004944)1.87714547
86Myositis (HP:0100614)1.87050486
87Xanthomatosis (HP:0000991)1.86169796
88Thyroid carcinoma (HP:0002890)1.85642314
89Generalized hypopigmentation of hair (HP:0011358)1.84319122
90Hemorrhage of the eye (HP:0011885)1.84317552
91Facial diplegia (HP:0001349)1.84174231
92Interstitial pulmonary disease (HP:0006530)1.83675587
93Abnormality of the common coagulation pathway (HP:0010990)1.83478021
94Protuberant abdomen (HP:0001538)1.82565776
95Keratoconjunctivitis sicca (HP:0001097)1.82258010
96Pulmonary artery stenosis (HP:0004415)1.81694729
97Prolonged bleeding time (HP:0003010)1.81582747
98Cellulitis (HP:0100658)1.81124100
99Abnormality of glutamine family amino acid metabolism (HP:0010902)1.81000433
100Cone-rod dystrophy (HP:0000548)1.80479211
101Macroorchidism (HP:0000053)1.79965129
102Widely spaced teeth (HP:0000687)1.77309054
103Disproportionate tall stature (HP:0001519)1.77120357
104Abnormality of purine metabolism (HP:0004352)1.74938632
105Curly hair (HP:0002212)1.74440277
106Abnormality of chloride homeostasis (HP:0011422)1.74405263
107Pustule (HP:0200039)1.72787320
108Broad metatarsal (HP:0001783)1.72747212
109Tetraparesis (HP:0002273)1.71770291
110Inflammation of the large intestine (HP:0002037)1.71591068
111Metaphyseal irregularity (HP:0003025)1.68060571
112Vascular calcification (HP:0004934)1.67505235
113Poikilocytosis (HP:0004447)1.66653438
114Amyloidosis (HP:0011034)1.66259317
115Decreased circulating renin level (HP:0003351)1.65963796
116Toxemia of pregnancy (HP:0100603)1.65895022
117Congenital sensorineural hearing impairment (HP:0008527)1.65726128
118Intrahepatic cholestasis (HP:0001406)1.65317267
119Thickened calvaria (HP:0002684)1.65081244
120Tubulointerstitial abnormality (HP:0001969)1.64897587
121Peripheral demyelination (HP:0011096)1.64656011
122Ovoid vertebral bodies (HP:0003300)1.64104145
123Cardiomegaly (HP:0001640)1.62560180
124Acute myeloid leukemia (HP:0004808)1.62517583
125Premature skin wrinkling (HP:0100678)1.62313619
126Increased CSF protein (HP:0002922)1.61957472
127Subacute progressive viral hepatitis (HP:0006572)1.61492784
128Syncope (HP:0001279)1.61477534
129Mediastinal lymphadenopathy (HP:0100721)1.61056446
130Osteomyelitis (HP:0002754)1.60289667
131Peritonitis (HP:0002586)1.60183469
132Frequent falls (HP:0002359)1.59664494
133Cardiovascular calcification (HP:0011915)1.59353709
134Hepatocellular carcinoma (HP:0001402)1.59105289
135Coarse hair (HP:0002208)1.58708527
136Mutism (HP:0002300)1.58031103
137Loss of speech (HP:0002371)1.57519615
138Spinal muscular atrophy (HP:0007269)1.57510001
139Urticaria (HP:0001025)1.57371774
140Depressed nasal tip (HP:0000437)1.56424711
141Mitral valve prolapse (HP:0001634)1.56127381
142Hypoalphalipoproteinemia (HP:0003233)1.55292686
143Cerebral hemorrhage (HP:0001342)1.54592649
144Thrombophlebitis (HP:0004418)1.53852768
145Absent frontal sinuses (HP:0002688)1.53455951

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TGFBR23.94062355
2ACVR1B3.64895849
3EPHB12.83318220
4MAP3K142.72495344
5TIE12.49202068
6TYK22.41490682
7TAOK32.37594270
8CAMKK22.02696421
9IRAK42.02195227
10IRAK31.97180339
11LATS11.94989101
12EPHA31.85057659
13ERN11.84681165
14MAP3K21.82965812
15IKBKE1.80365688
16NUAK11.79866992
17CAMK1D1.78271886
18KIT1.76865488
19AKT31.75641112
20JAK11.70948640
21TRPM71.64455318
22FER1.61297643
23PTK2B1.60082850
24PDK21.58054712
25YES11.57616497
26FRK1.55960917
27MAP2K31.52319842
28TBK11.51356052
29STK31.50687695
30FGFR31.49851722
31NEK91.49762685
32INSRR1.45606287
33IRAK11.45377721
34PTK61.43634018
35MAP3K31.42458877
36CDK61.39278925
37GRK71.32772882
38KDR1.32369201
39CAMK1G1.32366677
40CSK1.30873667
41JAK31.26127845
42ERBB31.24662649
43STK101.23592946
44IKBKB1.23045301
45CSF1R1.20049004
46ITK1.19046484
47MATK1.19014398
48CHUK1.18904088
49RIPK11.18251083
50FGFR41.17595265
51BMPR21.16009352
52TEC1.14732644
53MAPK151.14555682
54PDGFRB1.08811460
55FGFR21.08712224
56PINK11.06382244
57JAK21.04634674
58MST40.99268332
59CDK120.95206181
60STK390.94498464
61PRKAA20.91723804
62DDR20.91403518
63SGK30.90180073
64MET0.87030870
65STK40.86870469
66RIPK40.86336624
67SIK10.86045249
68KSR10.85738399
69STK38L0.85230964
70HCK0.82337499
71GSK3A0.82269839
72MAP4K10.81590277
73NLK0.81497888
74DMPK0.81257224
75CDK90.80666787
76WNK10.80643392
77BMPR1B0.80218983
78BTK0.78331191
79PIM10.78276084
80TTN0.78263066
81MYLK0.76655859
82CLK10.75923816
83MAP3K130.75327697
84STK110.74957270
85BLK0.74873806
86HIPK20.74445754
87OXSR10.73956869
88EGFR0.71252195
89WNK40.70853986
90PIK3CA0.70777202
91CCNB10.69633842
92PIK3CG0.69107852
93DAPK20.67506517
94PDGFRA0.66872446
95BRSK20.66778149
96SGK20.65597950
97MAPK70.64116735
98ABL10.63966681
99LCK0.63899509
100MAP3K120.63884233
101IGF1R0.62938275
102RET0.62536277
103MELK0.62184956
104IRAK20.61856551
105ZAP700.61722022
106NEK60.60799384
107CAMK40.59991897
108PDPK10.59168999
109MAP3K70.58809430
110FGR0.58709047
111MARK30.58022771
112MAP2K10.57576272
113DYRK1B0.56086781
114ADRBK20.56008180
115STK240.55572951
116PRKCH0.55234204
117MST1R0.54134518
118PRKCE0.53374793
119PAK30.53334376
120PTK20.53309556
121PLK20.52177691
122PBK0.52155496
123PRKG20.51775956
124PDK10.51331289
125BMX0.51031754
126PRKCQ0.50815065
127STK380.50583170
128LYN0.50246802
129MAPKAPK50.48325704
130MAP3K10.48263699
131MAPK120.47770794
132SGK2230.46881875
133SGK4940.46881875
134ADRBK10.46176182
135TGFBR10.45350886
136PRKD10.44761171
137MAP3K60.43971928
138TXK0.41840696
139MUSK0.40046717
140PAK20.39341560
141ERBB20.38300276

Predicted pathways (KEGG)

RankGene SetZ-score
1Staphylococcus aureus infection_Homo sapiens_hsa051502.88057500
2Complement and coagulation cascades_Homo sapiens_hsa046101.96552427
3Leishmaniasis_Homo sapiens_hsa051401.89786635
4Osteoclast differentiation_Homo sapiens_hsa043801.84066772
5Malaria_Homo sapiens_hsa051441.66276248
6Toll-like receptor signaling pathway_Homo sapiens_hsa046201.65831523
7Lysosome_Homo sapiens_hsa041421.62399230
8Caffeine metabolism_Homo sapiens_hsa002321.54809583
9Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.49113693
10Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.48555660
11ABC transporters_Homo sapiens_hsa020101.46103376
12NF-kappa B signaling pathway_Homo sapiens_hsa040641.45260259
13Leukocyte transendothelial migration_Homo sapiens_hsa046701.43522819
14Other glycan degradation_Homo sapiens_hsa005111.42274185
15Pertussis_Homo sapiens_hsa051331.38667551
16Pentose and glucuronate interconversions_Homo sapiens_hsa000401.36879310
17Nitrogen metabolism_Homo sapiens_hsa009101.36774901
18Glycosaminoglycan degradation_Homo sapiens_hsa005311.36352051
19Toxoplasmosis_Homo sapiens_hsa051451.36234643
20PPAR signaling pathway_Homo sapiens_hsa033201.19721498
21Primary bile acid biosynthesis_Homo sapiens_hsa001201.19066531
22NOD-like receptor signaling pathway_Homo sapiens_hsa046211.16205096
23B cell receptor signaling pathway_Homo sapiens_hsa046621.15515049
24TNF signaling pathway_Homo sapiens_hsa046681.14615438
25Measles_Homo sapiens_hsa051621.12090590
26Tuberculosis_Homo sapiens_hsa051521.11886337
27Vitamin digestion and absorption_Homo sapiens_hsa049771.11575780
28Hematopoietic cell lineage_Homo sapiens_hsa046401.09413055
29Histidine metabolism_Homo sapiens_hsa003401.08639705
30RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.04750838
31Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.04654726
32Jak-STAT signaling pathway_Homo sapiens_hsa046301.04481823
33Lysine degradation_Homo sapiens_hsa003101.03032835
34Platelet activation_Homo sapiens_hsa046111.02645894
35Influenza A_Homo sapiens_hsa051641.01814572
36Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.01701104
37Hepatitis C_Homo sapiens_hsa051601.00670774
38Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.99534807
39ECM-receptor interaction_Homo sapiens_hsa045120.99112420
40Fatty acid degradation_Homo sapiens_hsa000710.98873408
41Dorso-ventral axis formation_Homo sapiens_hsa043200.98712082
42Focal adhesion_Homo sapiens_hsa045100.98372488
43Adherens junction_Homo sapiens_hsa045200.98249803
44Chemokine signaling pathway_Homo sapiens_hsa040620.94240946
45AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.93698898
46Intestinal immune network for IgA production_Homo sapiens_hsa046720.91931092
47Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.91914140
48Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.90768328
49Tryptophan metabolism_Homo sapiens_hsa003800.87736581
50Transcriptional misregulation in cancer_Homo sapiens_hsa052020.87591805
51Amoebiasis_Homo sapiens_hsa051460.87361064
52Small cell lung cancer_Homo sapiens_hsa052220.85662055
53Pancreatic cancer_Homo sapiens_hsa052120.85123763
54Insulin resistance_Homo sapiens_hsa049310.84431360
55Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.84101309
56Renin-angiotensin system_Homo sapiens_hsa046140.82169588
57Chronic myeloid leukemia_Homo sapiens_hsa052200.81350312
58Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.81296554
59Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.79333077
60Herpes simplex infection_Homo sapiens_hsa051680.78310877
61Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.77785324
62Hepatitis B_Homo sapiens_hsa051610.75780581
63Adipocytokine signaling pathway_Homo sapiens_hsa049200.75158666
64Ovarian steroidogenesis_Homo sapiens_hsa049130.75131013
65Starch and sucrose metabolism_Homo sapiens_hsa005000.74378438
66Rheumatoid arthritis_Homo sapiens_hsa053230.74338985
67Fatty acid biosynthesis_Homo sapiens_hsa000610.74227361
68Sphingolipid metabolism_Homo sapiens_hsa006000.74024204
69Salmonella infection_Homo sapiens_hsa051320.73520907
70Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.72865662
71Viral myocarditis_Homo sapiens_hsa054160.72760832
72Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.72564098
73Renin secretion_Homo sapiens_hsa049240.72229144
74Bile secretion_Homo sapiens_hsa049760.72133643
75Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.71758453
76Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.71337792
77Prostate cancer_Homo sapiens_hsa052150.70936944
78Phagosome_Homo sapiens_hsa041450.70906301
79Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.70382668
80Sulfur metabolism_Homo sapiens_hsa009200.69685088
81Legionellosis_Homo sapiens_hsa051340.69525383
82African trypanosomiasis_Homo sapiens_hsa051430.69406236
83Carbohydrate digestion and absorption_Homo sapiens_hsa049730.68598149
84Notch signaling pathway_Homo sapiens_hsa043300.68424027
85Allograft rejection_Homo sapiens_hsa053300.68241920
86Proteoglycans in cancer_Homo sapiens_hsa052050.67820990
87Mineral absorption_Homo sapiens_hsa049780.67819164
88Collecting duct acid secretion_Homo sapiens_hsa049660.67682017
89Arginine biosynthesis_Homo sapiens_hsa002200.67250120
90Apoptosis_Homo sapiens_hsa042100.66265108
91Circadian rhythm_Homo sapiens_hsa047100.65970376
92Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.63961904
93Shigellosis_Homo sapiens_hsa051310.61878045
94Regulation of actin cytoskeleton_Homo sapiens_hsa048100.61875125
95Sphingolipid signaling pathway_Homo sapiens_hsa040710.61532879
96Steroid hormone biosynthesis_Homo sapiens_hsa001400.60971001
97mTOR signaling pathway_Homo sapiens_hsa041500.60353262
98Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.59929078
99Inositol phosphate metabolism_Homo sapiens_hsa005620.58537916
100FoxO signaling pathway_Homo sapiens_hsa040680.58338086
101Ether lipid metabolism_Homo sapiens_hsa005650.58183135
102Graft-versus-host disease_Homo sapiens_hsa053320.58014686
103Antigen processing and presentation_Homo sapiens_hsa046120.57895788
104Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.57462236
105Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.57051557
106Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.56438372
107Chemical carcinogenesis_Homo sapiens_hsa052040.56436807
108Fatty acid metabolism_Homo sapiens_hsa012120.55398483
109Endocytosis_Homo sapiens_hsa041440.55053257
110SNARE interactions in vesicular transport_Homo sapiens_hsa041300.55024788
111Peroxisome_Homo sapiens_hsa041460.54875860
112Steroid biosynthesis_Homo sapiens_hsa001000.54219944
113MicroRNAs in cancer_Homo sapiens_hsa052060.54214003
114Renal cell carcinoma_Homo sapiens_hsa052110.53340192
115Phosphatidylinositol signaling system_Homo sapiens_hsa040700.53262720
116HIF-1 signaling pathway_Homo sapiens_hsa040660.52897469
117Phospholipase D signaling pathway_Homo sapiens_hsa040720.52453429
118Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.52350891
119Protein digestion and absorption_Homo sapiens_hsa049740.52246175
120Choline metabolism in cancer_Homo sapiens_hsa052310.52181005
121Retinol metabolism_Homo sapiens_hsa008300.50894232
122Maturity onset diabetes of the young_Homo sapiens_hsa049500.50860296
123Drug metabolism - other enzymes_Homo sapiens_hsa009830.50779571
124Prolactin signaling pathway_Homo sapiens_hsa049170.49994879
125Fat digestion and absorption_Homo sapiens_hsa049750.49306523
126Asthma_Homo sapiens_hsa053100.48296983
127Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.48167337
128Type I diabetes mellitus_Homo sapiens_hsa049400.46914009

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