

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | protein neddylation (GO:0045116) | 6.82188978 |
| 2 | DNA deamination (GO:0045006) | 6.42048706 |
| 3 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.49917451 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 5.43189914 |
| 5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.43189914 |
| 6 | water-soluble vitamin biosynthetic process (GO:0042364) | 5.30945623 |
| 7 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.16757430 |
| 8 | terpenoid biosynthetic process (GO:0016114) | 5.05505722 |
| 9 | chaperone-mediated protein transport (GO:0072321) | 4.90260286 |
| 10 | cytidine metabolic process (GO:0046087) | 4.70386150 |
| 11 | cytidine catabolic process (GO:0006216) | 4.70386150 |
| 12 | cytidine deamination (GO:0009972) | 4.70386150 |
| 13 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.44542892 |
| 14 | protein complex biogenesis (GO:0070271) | 4.32339626 |
| 15 | proteasome assembly (GO:0043248) | 4.20154023 |
| 16 | respiratory electron transport chain (GO:0022904) | 4.17224378 |
| 17 | electron transport chain (GO:0022900) | 4.12985502 |
| 18 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.04689625 |
| 19 | behavioral response to nicotine (GO:0035095) | 3.85792881 |
| 20 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.78484106 |
| 21 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.74150403 |
| 22 | NADH dehydrogenase complex assembly (GO:0010257) | 3.74150403 |
| 23 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.74150403 |
| 24 | GTP biosynthetic process (GO:0006183) | 3.71996898 |
| 25 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.57749092 |
| 26 | cytochrome complex assembly (GO:0017004) | 3.55834690 |
| 27 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.53221685 |
| 28 | ribosomal small subunit assembly (GO:0000028) | 3.51364769 |
| 29 | hydrogen ion transmembrane transport (GO:1902600) | 3.50892890 |
| 30 | regulation of regulatory T cell differentiation (GO:0045589) | 3.45561390 |
| 31 | regulation of chronic inflammatory response (GO:0002676) | 3.40762777 |
| 32 | sequestering of actin monomers (GO:0042989) | 3.38890549 |
| 33 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.37736560 |
| 34 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.37736560 |
| 35 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.34146794 |
| 36 | negative regulation of systemic arterial blood pressure (GO:0003085) | 3.32413226 |
| 37 | protein peptidyl-prolyl isomerization (GO:0000413) | 3.30913398 |
| 38 | respiratory chain complex IV assembly (GO:0008535) | 3.29868680 |
| 39 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.25294284 |
| 40 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.25294284 |
| 41 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.25294284 |
| 42 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.24775251 |
| 43 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.22866991 |
| 44 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.22866991 |
| 45 | proton transport (GO:0015992) | 3.22316195 |
| 46 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 3.19857516 |
| 47 | UTP biosynthetic process (GO:0006228) | 3.18306742 |
| 48 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.18172947 |
| 49 | hydrogen transport (GO:0006818) | 3.16852155 |
| 50 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.16656213 |
| 51 | regulation of mitochondrial translation (GO:0070129) | 3.14432029 |
| 52 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.13185041 |
| 53 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.10944159 |
| 54 | energy homeostasis (GO:0097009) | 3.08202872 |
| 55 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.06950820 |
| 56 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.06950820 |
| 57 | protein-cofactor linkage (GO:0018065) | 3.06069153 |
| 58 | maturation of SSU-rRNA (GO:0030490) | 3.04473302 |
| 59 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.04370576 |
| 60 | cellular response to interleukin-15 (GO:0071350) | 3.03919633 |
| 61 | negative regulation of mast cell activation (GO:0033004) | 3.02312302 |
| 62 | angiogenesis involved in wound healing (GO:0060055) | 3.00500701 |
| 63 | ATP biosynthetic process (GO:0006754) | 2.99180207 |
| 64 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.98963534 |
| 65 | platelet dense granule organization (GO:0060155) | 2.95862729 |
| 66 | replication fork processing (GO:0031297) | 2.94831043 |
| 67 | signal peptide processing (GO:0006465) | 2.88950641 |
| 68 | negative regulation of ligase activity (GO:0051352) | 2.88852291 |
| 69 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.88852291 |
| 70 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.88203292 |
| 71 | termination of RNA polymerase III transcription (GO:0006386) | 2.86099466 |
| 72 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.86099466 |
| 73 | adaptation of signaling pathway (GO:0023058) | 2.84529560 |
| 74 | isoprenoid biosynthetic process (GO:0008299) | 2.82533886 |
| 75 | positive regulation of cell fate commitment (GO:0010455) | 2.82313855 |
| 76 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.81355813 |
| 77 | intracellular protein transmembrane import (GO:0044743) | 2.80361917 |
| 78 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.76238341 |
| 79 | UTP metabolic process (GO:0046051) | 2.75460437 |
| 80 | base-excision repair, AP site formation (GO:0006285) | 2.74457075 |
| 81 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.66996525 |
| 82 | response to redox state (GO:0051775) | 2.66185480 |
| 83 | positive regulation of cell cycle arrest (GO:0071158) | 2.63408484 |
| 84 | mast cell activation (GO:0045576) | 2.61451718 |
| 85 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.61220473 |
| 86 | DNA strand renaturation (GO:0000733) | 2.61200285 |
| 87 | positive regulation of defense response to virus by host (GO:0002230) | 2.60424574 |
| 88 | ubiquinone biosynthetic process (GO:0006744) | 2.60334217 |
| 89 | indole-containing compound catabolic process (GO:0042436) | 2.58449052 |
| 90 | indolalkylamine catabolic process (GO:0046218) | 2.58449052 |
| 91 | tryptophan catabolic process (GO:0006569) | 2.58449052 |
| 92 | positive regulation of tolerance induction (GO:0002645) | 2.58235516 |
| 93 | kynurenine metabolic process (GO:0070189) | 2.56493031 |
| 94 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.55567125 |
| 95 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.54728322 |
| 96 | dopamine transport (GO:0015872) | 2.54496985 |
| 97 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.54196997 |
| 98 | head development (GO:0060322) | 2.53865351 |
| 99 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.53606520 |
| 100 | resolution of meiotic recombination intermediates (GO:0000712) | 2.52907236 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.58731630 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.99603237 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.82263316 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.69629301 |
| 5 | VDR_22108803_ChIP-Seq_LS180_Human | 3.34870673 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.02504073 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.93716817 |
| 8 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.85063411 |
| 9 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.81959594 |
| 10 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.80466259 |
| 11 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.78628929 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.68685289 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.67717451 |
| 14 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.55939543 |
| 15 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.45514591 |
| 16 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.44373923 |
| 17 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.11426524 |
| 18 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.05098403 |
| 19 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.03999309 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.99801365 |
| 21 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.88574177 |
| 22 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.83087436 |
| 23 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.74552971 |
| 24 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.70414590 |
| 25 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.64632189 |
| 26 | EWS_26573619_Chip-Seq_HEK293_Human | 1.62735516 |
| 27 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.60112025 |
| 28 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.58190729 |
| 29 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.55581614 |
| 30 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.52110810 |
| 31 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.51691687 |
| 32 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.41463036 |
| 33 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.39643103 |
| 34 | NCOR_22424771_ChIP-Seq_293T_Human | 1.38353380 |
| 35 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.37637821 |
| 36 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.33188109 |
| 37 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.33130727 |
| 38 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.32868896 |
| 39 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.31627460 |
| 40 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.28948925 |
| 41 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.28846594 |
| 42 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.28114031 |
| 43 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.28013035 |
| 44 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.28013035 |
| 45 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.26983830 |
| 46 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.26295868 |
| 47 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.22943800 |
| 48 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.20619444 |
| 49 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.18788807 |
| 50 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.17504756 |
| 51 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.15288747 |
| 52 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.14967051 |
| 53 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.14852779 |
| 54 | AR_20517297_ChIP-Seq_VCAP_Human | 1.14387512 |
| 55 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.13981488 |
| 56 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.11842901 |
| 57 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.11758058 |
| 58 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.11102304 |
| 59 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.10624381 |
| 60 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.10624381 |
| 61 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.10010326 |
| 62 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.09106534 |
| 63 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.08545827 |
| 64 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.08519524 |
| 65 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.08184450 |
| 66 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.07853060 |
| 67 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.02461556 |
| 68 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.01919135 |
| 69 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.01492968 |
| 70 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.01371321 |
| 71 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.00798941 |
| 72 | P300_19829295_ChIP-Seq_ESCs_Human | 1.00587176 |
| 73 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.99634005 |
| 74 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.99539795 |
| 75 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.99262052 |
| 76 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.99097280 |
| 77 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.98377267 |
| 78 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.98193406 |
| 79 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.97987762 |
| 80 | FUS_26573619_Chip-Seq_HEK293_Human | 0.97109741 |
| 81 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.96285444 |
| 82 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.91776310 |
| 83 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.91050471 |
| 84 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.90578889 |
| 85 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.90348278 |
| 86 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.90348278 |
| 87 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.90007548 |
| 88 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.89401914 |
| 89 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.87540132 |
| 90 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.87359900 |
| 91 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 0.87333560 |
| 92 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.86978566 |
| 93 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.86261386 |
| 94 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.86191439 |
| 95 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.85565596 |
| 96 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.85071584 |
| 97 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.84960459 |
| 98 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.84478247 |
| 99 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.84172066 |
| 100 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.83990017 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002277_abnormal_respiratory_mucosa | 3.22252348 |
| 2 | MP0004147_increased_porphyrin_level | 3.11903948 |
| 3 | MP0008872_abnormal_physiological_respon | 2.93707627 |
| 4 | MP0002102_abnormal_ear_morphology | 2.91748975 |
| 5 | MP0003011_delayed_dark_adaptation | 2.75054004 |
| 6 | MP0003183_abnormal_peptide_metabolism | 2.61652252 |
| 7 | MP0006054_spinal_hemorrhage | 2.48581007 |
| 8 | MP0001873_stomach_inflammation | 2.43842827 |
| 9 | MP0004742_abnormal_vestibular_system | 2.34614399 |
| 10 | MP0001485_abnormal_pinna_reflex | 2.27069490 |
| 11 | MP0005671_abnormal_response_to | 2.26985427 |
| 12 | MP0008875_abnormal_xenobiotic_pharmacok | 2.03156336 |
| 13 | MP0002876_abnormal_thyroid_physiology | 1.96287278 |
| 14 | MP0003878_abnormal_ear_physiology | 1.94393068 |
| 15 | MP0005377_hearing/vestibular/ear_phenot | 1.94393068 |
| 16 | MP0002638_abnormal_pupillary_reflex | 1.89385742 |
| 17 | MP0004885_abnormal_endolymph | 1.84849937 |
| 18 | MP0009785_altered_susceptibility_to | 1.83116429 |
| 19 | MP0003195_calcinosis | 1.77011168 |
| 20 | MP0003283_abnormal_digestive_organ | 1.75753929 |
| 21 | MP0000685_abnormal_immune_system | 1.75545721 |
| 22 | MP0005167_abnormal_blood-brain_barrier | 1.72429906 |
| 23 | MP0004145_abnormal_muscle_electrophysio | 1.66244205 |
| 24 | MP0005257_abnormal_intraocular_pressure | 1.65541841 |
| 25 | MP0008877_abnormal_DNA_methylation | 1.60168145 |
| 26 | MP0006292_abnormal_olfactory_placode | 1.58222132 |
| 27 | MP0001905_abnormal_dopamine_level | 1.54315706 |
| 28 | MP0003866_abnormal_defecation | 1.52777760 |
| 29 | MP0001835_abnormal_antigen_presentation | 1.51140373 |
| 30 | MP0002138_abnormal_hepatobiliary_system | 1.50645805 |
| 31 | MP0001968_abnormal_touch/_nociception | 1.48516080 |
| 32 | MP0002736_abnormal_nociception_after | 1.48058551 |
| 33 | MP0001293_anophthalmia | 1.46706757 |
| 34 | MP0005551_abnormal_eye_electrophysiolog | 1.46366753 |
| 35 | MP0003718_maternal_effect | 1.46327741 |
| 36 | MP0009745_abnormal_behavioral_response | 1.41749785 |
| 37 | MP0004142_abnormal_muscle_tone | 1.41513321 |
| 38 | MP0001800_abnormal_humoral_immune | 1.41049602 |
| 39 | MP0002735_abnormal_chemical_nociception | 1.40030748 |
| 40 | MP0005645_abnormal_hypothalamus_physiol | 1.36094679 |
| 41 | MP0001529_abnormal_vocalization | 1.34249790 |
| 42 | MP0005387_immune_system_phenotype | 1.32974363 |
| 43 | MP0001790_abnormal_immune_system | 1.32974363 |
| 44 | MP0003786_premature_aging | 1.27011581 |
| 45 | MP0002163_abnormal_gland_morphology | 1.26995071 |
| 46 | MP0000569_abnormal_digit_pigmentation | 1.26935529 |
| 47 | MP0001486_abnormal_startle_reflex | 1.25292813 |
| 48 | MP0005646_abnormal_pituitary_gland | 1.23881252 |
| 49 | MP0006036_abnormal_mitochondrial_physio | 1.21960335 |
| 50 | MP0004215_abnormal_myocardial_fiber | 1.19680395 |
| 51 | MP0001502_abnormal_circadian_rhythm | 1.19215657 |
| 52 | MP0001919_abnormal_reproductive_system | 1.11219166 |
| 53 | MP0001970_abnormal_pain_threshold | 1.10416507 |
| 54 | MP0002148_abnormal_hypersensitivity_rea | 1.10025462 |
| 55 | MP0003567_abnormal_fetal_cardiomyocyte | 1.07187141 |
| 56 | MP0002693_abnormal_pancreas_physiology | 1.05891954 |
| 57 | MP0002160_abnormal_reproductive_system | 1.05758173 |
| 58 | MP0005389_reproductive_system_phenotype | 1.02358619 |
| 59 | MP0003693_abnormal_embryo_hatching | 1.02076856 |
| 60 | MP0001440_abnormal_grooming_behavior | 1.00897402 |
| 61 | MP0003186_abnormal_redox_activity | 0.99354210 |
| 62 | MP0002272_abnormal_nervous_system | 0.99028422 |
| 63 | MP0001986_abnormal_taste_sensitivity | 0.98032413 |
| 64 | MP0003787_abnormal_imprinting | 0.96454609 |
| 65 | MP0002733_abnormal_thermal_nociception | 0.95921098 |
| 66 | MP0003122_maternal_imprinting | 0.95890180 |
| 67 | MP0006276_abnormal_autonomic_nervous | 0.92857064 |
| 68 | MP0002234_abnormal_pharynx_morphology | 0.92673001 |
| 69 | MP0005448_abnormal_energy_balance | 0.92310387 |
| 70 | MP0003880_abnormal_central_pattern | 0.91276593 |
| 71 | MP0005636_abnormal_mineral_homeostasis | 0.91074615 |
| 72 | MP0003638_abnormal_response/metabolism_ | 0.89096281 |
| 73 | MP0005085_abnormal_gallbladder_physiolo | 0.87392593 |
| 74 | MP0004043_abnormal_pH_regulation | 0.86784450 |
| 75 | MP0001984_abnormal_olfaction | 0.83835122 |
| 76 | MP0005000_abnormal_immune_tolerance | 0.82746463 |
| 77 | MP0010155_abnormal_intestine_physiology | 0.81975068 |
| 78 | MP0005084_abnormal_gallbladder_morpholo | 0.81636620 |
| 79 | MP0008775_abnormal_heart_ventricle | 0.81174410 |
| 80 | MP0002723_abnormal_immune_serum | 0.81050716 |
| 81 | MP0006035_abnormal_mitochondrial_morpho | 0.79022235 |
| 82 | MP0001663_abnormal_digestive_system | 0.78773729 |
| 83 | MP0001501_abnormal_sleep_pattern | 0.75229496 |
| 84 | MP0001765_abnormal_ion_homeostasis | 0.74197356 |
| 85 | MP0002420_abnormal_adaptive_immunity | 0.73465731 |
| 86 | MP0003315_abnormal_perineum_morphology | 0.72958498 |
| 87 | MP0002064_seizures | 0.72127761 |
| 88 | MP0001819_abnormal_immune_cell | 0.71764059 |
| 89 | MP0005310_abnormal_salivary_gland | 0.70566925 |
| 90 | MP0005025_abnormal_response_to | 0.70539563 |
| 91 | MP0000613_abnormal_salivary_gland | 0.70395928 |
| 92 | MP0005670_abnormal_white_adipose | 0.68759249 |
| 93 | MP0001666_abnormal_nutrient_absorption | 0.67415606 |
| 94 | MP0001845_abnormal_inflammatory_respons | 0.66669376 |
| 95 | MP0003938_abnormal_ear_development | 0.66652294 |
| 96 | MP0000026_abnormal_inner_ear | 0.64610686 |
| 97 | MP0002063_abnormal_learning/memory/cond | 0.64588472 |
| 98 | MP0002837_dystrophic_cardiac_calcinosis | 0.64131998 |
| 99 | MP0008789_abnormal_olfactory_epithelium | 0.63919178 |
| 100 | MP0000372_irregular_coat_pigmentation | 0.62680440 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.57398285 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.30469434 |
| 3 | Increased CSF lactate (HP:0002490) | 4.06051061 |
| 4 | Methylmalonic aciduria (HP:0012120) | 4.05793910 |
| 5 | Congenital stationary night blindness (HP:0007642) | 3.95858553 |
| 6 | Acute encephalopathy (HP:0006846) | 3.86985967 |
| 7 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.81376060 |
| 8 | Progressive macrocephaly (HP:0004481) | 3.75249529 |
| 9 | Hepatocellular necrosis (HP:0001404) | 3.74970622 |
| 10 | 3-Methylglutaconic aciduria (HP:0003535) | 3.46731945 |
| 11 | Methylmalonic acidemia (HP:0002912) | 3.45531825 |
| 12 | Increased hepatocellular lipid droplets (HP:0006565) | 3.40476220 |
| 13 | Hepatic necrosis (HP:0002605) | 3.23772045 |
| 14 | IgG deficiency (HP:0004315) | 3.17298359 |
| 15 | Agitation (HP:0000713) | 3.16598293 |
| 16 | Cerebral hypomyelination (HP:0006808) | 3.10467747 |
| 17 | Abnormality of the renal cortex (HP:0011035) | 3.09830011 |
| 18 | Lipid accumulation in hepatocytes (HP:0006561) | 3.05678859 |
| 19 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 3.03960418 |
| 20 | Abnormality of B cell number (HP:0010975) | 2.94888767 |
| 21 | Optic disc pallor (HP:0000543) | 2.86790623 |
| 22 | Molar tooth sign on MRI (HP:0002419) | 2.85513133 |
| 23 | Abnormality of midbrain morphology (HP:0002418) | 2.85513133 |
| 24 | Pancreatic cysts (HP:0001737) | 2.80135696 |
| 25 | Delayed CNS myelination (HP:0002188) | 2.79175691 |
| 26 | Increased IgM level (HP:0003496) | 2.75007534 |
| 27 | Pendular nystagmus (HP:0012043) | 2.71183981 |
| 28 | Stomach cancer (HP:0012126) | 2.70097995 |
| 29 | Renal Fanconi syndrome (HP:0001994) | 2.66867497 |
| 30 | Cerebral edema (HP:0002181) | 2.55319666 |
| 31 | Oligodactyly (hands) (HP:0001180) | 2.55083324 |
| 32 | Autoimmune hemolytic anemia (HP:0001890) | 2.52478453 |
| 33 | Increased serum lactate (HP:0002151) | 2.51750030 |
| 34 | Congenital, generalized hypertrichosis (HP:0004540) | 2.49118089 |
| 35 | Colon cancer (HP:0003003) | 2.48159150 |
| 36 | Abolished electroretinogram (ERG) (HP:0000550) | 2.48001532 |
| 37 | Leukodystrophy (HP:0002415) | 2.43233455 |
| 38 | Renal cortical cysts (HP:0000803) | 2.42677389 |
| 39 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.41636415 |
| 40 | Papilledema (HP:0001085) | 2.40063280 |
| 41 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.39769850 |
| 42 | Respiratory failure (HP:0002878) | 2.39087443 |
| 43 | CNS hypomyelination (HP:0003429) | 2.34637502 |
| 44 | Pancreatic fibrosis (HP:0100732) | 2.33663415 |
| 45 | Lactic acidosis (HP:0003128) | 2.32766960 |
| 46 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.31820501 |
| 47 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.31820501 |
| 48 | Exertional dyspnea (HP:0002875) | 2.29605344 |
| 49 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.22754355 |
| 50 | Abnormality of the renal medulla (HP:0100957) | 2.20999273 |
| 51 | Oral leukoplakia (HP:0002745) | 2.20168561 |
| 52 | True hermaphroditism (HP:0010459) | 2.17854186 |
| 53 | Nephronophthisis (HP:0000090) | 2.16514297 |
| 54 | Abnormality of the pons (HP:0007361) | 2.14909507 |
| 55 | Sclerocornea (HP:0000647) | 2.10204385 |
| 56 | Abnormality of T cell number (HP:0011839) | 2.09316737 |
| 57 | Hypoproteinemia (HP:0003075) | 2.07516007 |
| 58 | Aplastic anemia (HP:0001915) | 2.06892047 |
| 59 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.05748916 |
| 60 | Broad alveolar ridges (HP:0000187) | 2.04818598 |
| 61 | Lethargy (HP:0001254) | 2.04333756 |
| 62 | Hypoalbuminemia (HP:0003073) | 2.02203091 |
| 63 | Abnormal albumin level (HP:0012116) | 2.02203091 |
| 64 | Pancytopenia (HP:0001876) | 2.00810313 |
| 65 | Increased intramyocellular lipid droplets (HP:0012240) | 2.00297174 |
| 66 | Abnormality of T cells (HP:0002843) | 1.99944624 |
| 67 | Volvulus (HP:0002580) | 1.99795362 |
| 68 | Cellular immunodeficiency (HP:0005374) | 1.98310765 |
| 69 | Progressive inability to walk (HP:0002505) | 1.96558632 |
| 70 | Stomatitis (HP:0010280) | 1.92606753 |
| 71 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.91019350 |
| 72 | Adactyly (HP:0009776) | 1.90920546 |
| 73 | Stenosis of the external auditory canal (HP:0000402) | 1.90653481 |
| 74 | Increased serum pyruvate (HP:0003542) | 1.89752910 |
| 75 | Medial flaring of the eyebrow (HP:0010747) | 1.88677360 |
| 76 | Abnormality of T cell physiology (HP:0011840) | 1.87653631 |
| 77 | Abnormality of the alveolar ridges (HP:0006477) | 1.87419870 |
| 78 | Hypoplasia of the pons (HP:0012110) | 1.87085086 |
| 79 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.86239031 |
| 80 | Type II lissencephaly (HP:0007260) | 1.86032267 |
| 81 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.85929708 |
| 82 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.85929708 |
| 83 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.85306687 |
| 84 | Absent/shortened dynein arms (HP:0200106) | 1.85306687 |
| 85 | Inability to walk (HP:0002540) | 1.83734739 |
| 86 | Abnormality of renal resorption (HP:0011038) | 1.82970318 |
| 87 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.81989192 |
| 88 | Reticulocytopenia (HP:0001896) | 1.81982990 |
| 89 | Asplenia (HP:0001746) | 1.81829817 |
| 90 | Abnormality of placental membranes (HP:0011409) | 1.81760509 |
| 91 | Amniotic constriction ring (HP:0009775) | 1.81760509 |
| 92 | Dicarboxylic aciduria (HP:0003215) | 1.80743858 |
| 93 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.80743858 |
| 94 | Parakeratosis (HP:0001036) | 1.80263603 |
| 95 | Autoimmune thrombocytopenia (HP:0001973) | 1.78012017 |
| 96 | CNS demyelination (HP:0007305) | 1.77550231 |
| 97 | X-linked dominant inheritance (HP:0001423) | 1.77511001 |
| 98 | Constricted visual fields (HP:0001133) | 1.76008796 |
| 99 | Hyperglycinemia (HP:0002154) | 1.73946333 |
| 100 | Exercise intolerance (HP:0003546) | 1.70018133 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 5.09134668 |
| 2 | VRK2 | 3.86162123 |
| 3 | TIE1 | 3.68872564 |
| 4 | PINK1 | 3.40453514 |
| 5 | TLK1 | 2.84364235 |
| 6 | GRK1 | 2.34549916 |
| 7 | NME1 | 2.19595223 |
| 8 | WNK4 | 2.18769113 |
| 9 | TAF1 | 2.18286569 |
| 10 | NUAK1 | 2.16966487 |
| 11 | ZAK | 2.11839968 |
| 12 | SIK2 | 2.00558736 |
| 13 | TRIM28 | 1.99477448 |
| 14 | TSSK6 | 1.99294407 |
| 15 | WNK3 | 1.94701986 |
| 16 | PASK | 1.89054913 |
| 17 | PDK2 | 1.76776106 |
| 18 | VRK1 | 1.70040735 |
| 19 | EIF2AK3 | 1.69321731 |
| 20 | BCR | 1.57597546 |
| 21 | MST4 | 1.52347655 |
| 22 | TEC | 1.52048256 |
| 23 | ADRBK2 | 1.47481814 |
| 24 | MAPKAPK3 | 1.42413173 |
| 25 | BUB1 | 1.40130774 |
| 26 | DYRK2 | 1.37726484 |
| 27 | MAP2K6 | 1.35915589 |
| 28 | BCKDK | 1.30699202 |
| 29 | PLK2 | 1.17464509 |
| 30 | FRK | 1.17430991 |
| 31 | MAP4K1 | 1.17155213 |
| 32 | CAMKK2 | 1.13832201 |
| 33 | TNIK | 1.13134680 |
| 34 | OXSR1 | 1.12228962 |
| 35 | KDR | 1.09380240 |
| 36 | MAP3K12 | 1.04673166 |
| 37 | STK39 | 1.01798659 |
| 38 | DAPK1 | 1.01542693 |
| 39 | FES | 1.01057169 |
| 40 | EIF2AK2 | 0.99414938 |
| 41 | PHKG2 | 0.99316522 |
| 42 | PHKG1 | 0.99316522 |
| 43 | ITK | 0.95073028 |
| 44 | PLK3 | 0.94278443 |
| 45 | STK16 | 0.89800084 |
| 46 | KIT | 0.89466334 |
| 47 | PBK | 0.86301813 |
| 48 | DAPK2 | 0.84047981 |
| 49 | CSNK1G3 | 0.83580745 |
| 50 | GRK5 | 0.82899802 |
| 51 | CDK19 | 0.81829151 |
| 52 | MAP4K2 | 0.81197712 |
| 53 | PRKCG | 0.79728243 |
| 54 | NEK1 | 0.78898764 |
| 55 | MAP2K7 | 0.77598907 |
| 56 | SYK | 0.77313731 |
| 57 | CSNK1A1L | 0.76515568 |
| 58 | SIK3 | 0.75716111 |
| 59 | NME2 | 0.75422438 |
| 60 | CAMKK1 | 0.72106447 |
| 61 | INSRR | 0.69336642 |
| 62 | CSNK1G2 | 0.68375367 |
| 63 | CASK | 0.65862392 |
| 64 | EIF2AK1 | 0.65616196 |
| 65 | CSNK1G1 | 0.65012074 |
| 66 | CDK8 | 0.64243224 |
| 67 | PIK3CG | 0.62978823 |
| 68 | SRPK1 | 0.60468465 |
| 69 | BMPR1B | 0.57047972 |
| 70 | PRKCQ | 0.56967370 |
| 71 | AURKA | 0.53349834 |
| 72 | PRKCH | 0.48493648 |
| 73 | IGF1R | 0.47468068 |
| 74 | EPHB2 | 0.44869461 |
| 75 | ADRBK1 | 0.43209238 |
| 76 | MINK1 | 0.42574715 |
| 77 | IRAK4 | 0.41831187 |
| 78 | LIMK1 | 0.39872728 |
| 79 | DAPK3 | 0.39191532 |
| 80 | LCK | 0.37795845 |
| 81 | MYLK | 0.37641593 |
| 82 | ALK | 0.37095186 |
| 83 | PRKCE | 0.36564499 |
| 84 | MAP3K11 | 0.36476816 |
| 85 | PRKCD | 0.35889149 |
| 86 | PRKCA | 0.34659364 |
| 87 | CAMK1 | 0.32505737 |
| 88 | GRK7 | 0.32112162 |
| 89 | PRKACA | 0.31365381 |
| 90 | CSNK2A1 | 0.31232943 |
| 91 | IKBKB | 0.31013692 |
| 92 | NEK2 | 0.30007843 |
| 93 | EPHA4 | 0.29630858 |
| 94 | CAMK2A | 0.29424356 |
| 95 | ZAP70 | 0.29235241 |
| 96 | OBSCN | 0.28668626 |
| 97 | TAOK1 | 0.28293860 |
| 98 | MAP3K4 | 0.28201777 |
| 99 | PIK3CA | 0.28085382 |
| 100 | CSNK2A2 | 0.26334902 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.66740404 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.87972682 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.29117354 |
| 4 | Protein export_Homo sapiens_hsa03060 | 2.44580430 |
| 5 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.38713719 |
| 6 | Alzheimers disease_Homo sapiens_hsa05010 | 2.35135182 |
| 7 | Ribosome_Homo sapiens_hsa03010 | 2.26222179 |
| 8 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.25219851 |
| 9 | Huntingtons disease_Homo sapiens_hsa05016 | 2.16160616 |
| 10 | RNA polymerase_Homo sapiens_hsa03020 | 2.11715965 |
| 11 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.04665833 |
| 12 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.03182933 |
| 13 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.91316498 |
| 14 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.85351477 |
| 15 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.76731307 |
| 16 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.68302515 |
| 17 | Basal transcription factors_Homo sapiens_hsa03022 | 1.63960579 |
| 18 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.62500541 |
| 19 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.61084889 |
| 20 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.54543645 |
| 21 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.53970966 |
| 22 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.47878237 |
| 23 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.47691513 |
| 24 | Homologous recombination_Homo sapiens_hsa03440 | 1.41458081 |
| 25 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.40090871 |
| 26 | Asthma_Homo sapiens_hsa05310 | 1.32669997 |
| 27 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.30964415 |
| 28 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.29676357 |
| 29 | Allograft rejection_Homo sapiens_hsa05330 | 1.28032762 |
| 30 | Phototransduction_Homo sapiens_hsa04744 | 1.26559130 |
| 31 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.26342968 |
| 32 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.25778604 |
| 33 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.20708643 |
| 34 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.20693820 |
| 35 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.15634190 |
| 36 | Peroxisome_Homo sapiens_hsa04146 | 1.13442092 |
| 37 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.10979981 |
| 38 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.10788816 |
| 39 | RNA degradation_Homo sapiens_hsa03018 | 1.10486726 |
| 40 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.09915321 |
| 41 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.09453230 |
| 42 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.01720230 |
| 43 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.01417862 |
| 44 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.00003936 |
| 45 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.97182459 |
| 46 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.96244718 |
| 47 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.95704102 |
| 48 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.94579124 |
| 49 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.94012887 |
| 50 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.93958628 |
| 51 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.92741883 |
| 52 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.86548076 |
| 53 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.86361089 |
| 54 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.85373684 |
| 55 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.83666309 |
| 56 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.83102785 |
| 57 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.81404516 |
| 58 | DNA replication_Homo sapiens_hsa03030 | 0.80777028 |
| 59 | Mismatch repair_Homo sapiens_hsa03430 | 0.80309283 |
| 60 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.78554625 |
| 61 | Purine metabolism_Homo sapiens_hsa00230 | 0.78500386 |
| 62 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.78297152 |
| 63 | Base excision repair_Homo sapiens_hsa03410 | 0.75763507 |
| 64 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.72713296 |
| 65 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.71627574 |
| 66 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.71256774 |
| 67 | RNA transport_Homo sapiens_hsa03013 | 0.70776395 |
| 68 | Metabolic pathways_Homo sapiens_hsa01100 | 0.69774662 |
| 69 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.69064489 |
| 70 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.66249345 |
| 71 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.65593667 |
| 72 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.64716611 |
| 73 | Spliceosome_Homo sapiens_hsa03040 | 0.61900325 |
| 74 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.59722981 |
| 75 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.59113106 |
| 76 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.55413772 |
| 77 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.55156781 |
| 78 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.54946350 |
| 79 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.53939904 |
| 80 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.53176219 |
| 81 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.50887738 |
| 82 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.50802412 |
| 83 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.47475029 |
| 84 | Retinol metabolism_Homo sapiens_hsa00830 | 0.47261148 |
| 85 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.47157201 |
| 86 | Salivary secretion_Homo sapiens_hsa04970 | 0.46760332 |
| 87 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.46476326 |
| 88 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.45067982 |
| 89 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.43136533 |
| 90 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.42831279 |
| 91 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.38741187 |
| 92 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.38118956 |
| 93 | Morphine addiction_Homo sapiens_hsa05032 | 0.37639129 |
| 94 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.37068212 |
| 95 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.36925346 |
| 96 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.35672645 |
| 97 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.35379516 |
| 98 | GABAergic synapse_Homo sapiens_hsa04727 | 0.32899582 |
| 99 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.31990942 |
| 100 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.31834819 |

