FDPSP8

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of skeletal muscle contraction (GO:0014819)7.18943969
2DNA deamination (GO:0045006)6.62371702
3negative regulation of cell aging (GO:0090344)6.18579388
4DNA strand renaturation (GO:0000733)5.96280639
5regulation of synapse structural plasticity (GO:0051823)5.61175767
6cellular response to ATP (GO:0071318)5.60855208
7mitotic cell cycle arrest (GO:0071850)5.30512340
8GDP-mannose metabolic process (GO:0019673)5.27928097
9cytidine metabolic process (GO:0046087)5.12014752
10cytidine catabolic process (GO:0006216)5.12014752
11cytidine deamination (GO:0009972)5.12014752
12transepithelial transport (GO:0070633)5.08957509
13detection of light stimulus involved in sensory perception (GO:0050962)5.08099305
14detection of light stimulus involved in visual perception (GO:0050908)5.08099305
15regulation of cytokine production involved in inflammatory response (GO:1900015)4.90891615
16meiotic chromosome segregation (GO:0045132)4.89480514
17regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.84914981
18estrogen biosynthetic process (GO:0006703)4.74084327
19purine deoxyribonucleotide catabolic process (GO:0009155)4.70701578
20protein carboxylation (GO:0018214)4.44989142
21peptidyl-glutamic acid carboxylation (GO:0017187)4.44989142
22pyrimidine ribonucleoside catabolic process (GO:0046133)4.35902185
23rRNA modification (GO:0000154)4.11145877
24base-excision repair, AP site formation (GO:0006285)4.08462169
25positive regulation of heat generation (GO:0031652)3.99671885
26sequestering of actin monomers (GO:0042989)3.83685341
27purinergic nucleotide receptor signaling pathway (GO:0035590)3.77092497
28lens fiber cell differentiation (GO:0070306)3.71539233
29respiratory chain complex IV assembly (GO:0008535)3.70556393
30rRNA methylation (GO:0031167)3.68409640
31behavioral response to nicotine (GO:0035095)3.60132400
32negative regulation of calcium ion transport into cytosol (GO:0010523)3.58352940
33regulation of interleukin-8 secretion (GO:2000482)3.49324894
34G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)3.49256634
35regulation of heat generation (GO:0031650)3.44585396
36metallo-sulfur cluster assembly (GO:0031163)3.40366422
37iron-sulfur cluster assembly (GO:0016226)3.40366422
38piRNA metabolic process (GO:0034587)3.33184737
39positive regulation of calcium-mediated signaling (GO:0050850)3.30427776
40RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.29768848
41tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.29768848
42T cell migration (GO:0072678)3.29405797
43cytochrome complex assembly (GO:0017004)3.28358076
44terpenoid biosynthetic process (GO:0016114)3.26455979
45deoxyribonucleotide catabolic process (GO:0009264)3.20440987
46cytolysis (GO:0019835)3.20406417
47sulfur amino acid catabolic process (GO:0000098)3.19855408
48mismatch repair (GO:0006298)3.15802720
49platelet dense granule organization (GO:0060155)3.15150107
50negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)3.10750051
51water-soluble vitamin biosynthetic process (GO:0042364)3.08942106
52negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.01991843
53negative regulation of execution phase of apoptosis (GO:1900118)2.99243200
54mast cell activation involved in immune response (GO:0002279)2.96326378
55mast cell degranulation (GO:0043303)2.96326378
56positive regulation of TOR signaling (GO:0032008)2.96117282
57positive regulation of interleukin-8 secretion (GO:2000484)2.95378731
58positive regulation of defense response to virus by host (GO:0002230)2.94954585
59secondary metabolite biosynthetic process (GO:0044550)2.91587463
60phosphatidylglycerol biosynthetic process (GO:0006655)2.91509012
61negative regulation by host of viral transcription (GO:0043922)2.90790046
62mannosylation (GO:0097502)2.90429409
63response to ATP (GO:0033198)2.88088869
64purine deoxyribonucleotide metabolic process (GO:0009151)2.87269845
65positive T cell selection (GO:0043368)2.87129667
66adenosine receptor signaling pathway (GO:0001973)2.85248566
67deoxyribose phosphate catabolic process (GO:0046386)2.84988017
68ATP synthesis coupled proton transport (GO:0015986)2.79658874
69energy coupled proton transport, down electrochemical gradient (GO:0015985)2.79658874
70Arp2/3 complex-mediated actin nucleation (GO:0034314)2.78364756
71positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.78361877
72regulation of cell aging (GO:0090342)2.77113351
73trivalent inorganic anion homeostasis (GO:0072506)2.76847042
74phosphate ion homeostasis (GO:0055062)2.76847042
75negative regulation of mast cell activation (GO:0033004)2.76350537
76regulation of phospholipid biosynthetic process (GO:0071071)2.75965329
77type B pancreatic cell proliferation (GO:0044342)2.74435095
78positive thymic T cell selection (GO:0045059)2.73870618
79cellular anion homeostasis (GO:0030002)2.72776359
80peptidyl-glutamic acid modification (GO:0018200)2.70946165
81transcription elongation from RNA polymerase III promoter (GO:0006385)2.68343888
82termination of RNA polymerase III transcription (GO:0006386)2.68343888
83positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)2.67557191
84glutathione derivative metabolic process (GO:1901685)2.67428074
85glutathione derivative biosynthetic process (GO:1901687)2.67428074
86phosphatidylethanolamine biosynthetic process (GO:0006646)2.65465170
87positive regulation of leukocyte mediated cytotoxicity (GO:0001912)2.64715998
88preassembly of GPI anchor in ER membrane (GO:0016254)2.64343977
89negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.63858999
90negative regulation of ligase activity (GO:0051352)2.63858999
91cardiolipin metabolic process (GO:0032048)2.63693400
92positive regulation of natural killer cell mediated immunity (GO:0002717)2.63001927
93positive regulation of protein kinase C signaling (GO:0090037)2.63001562
94axoneme assembly (GO:0035082)2.62074872
95DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.59251402
96adaptation of signaling pathway (GO:0023058)2.58628836
97melanin biosynthetic process (GO:0042438)2.57454892
98regulation of cellular amino acid metabolic process (GO:0006521)2.57345576
99ubiquinone biosynthetic process (GO:0006744)2.56828453
100response to pheromone (GO:0019236)2.56625094

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.25480942
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.03168236
3JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.82422081
4GABP_17652178_ChIP-ChIP_JURKAT_Human2.79320500
5CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.54740700
6NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.48331164
7E2F1_20622854_ChIP-Seq_HELA_Human2.46589096
8MAF_26560356_Chip-Seq_TH2_Human2.46271024
9XRN2_22483619_ChIP-Seq_HELA_Human2.44515669
10P68_20966046_ChIP-Seq_HELA_Human2.43540809
11CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.41495939
12BCL6_27268052_Chip-Seq_Bcells_Human2.34659261
13E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.16881288
14HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.13487305
15EST1_17652178_ChIP-ChIP_JURKAT_Human2.13146141
16BCOR_27268052_Chip-Seq_Bcells_Human2.08687614
17VDR_21846776_ChIP-Seq_THP-1_Human2.08138917
18BP1_19119308_ChIP-ChIP_Hs578T_Human2.07303167
19YY1_22570637_ChIP-Seq_MALME-3M_Human2.05673848
20DMRT1_21621532_ChIP-ChIP_FETAL_Ovary2.05190500
21VDR_23849224_ChIP-Seq_CD4+_Human2.04861681
22RBPJ_21746931_ChIP-Seq_IB4-LCL_Human2.03889373
23CIITA_25753668_ChIP-Seq_RAJI_Human1.99615418
24IRF8_21731497_ChIP-ChIP_J774_Mouse1.98508316
25EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.97355816
26ETS1_20019798_ChIP-Seq_JURKAT_Human1.96937999
27CTCF_20526341_ChIP-Seq_ESCs_Human1.96312815
28STAT6_21828071_ChIP-Seq_BEAS2B_Human1.95136124
29ELF1_17652178_ChIP-ChIP_JURKAT_Human1.95091587
30TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.87666597
31PHF8_20622854_ChIP-Seq_HELA_Human1.81483261
32NANOG_20526341_ChIP-Seq_ESCs_Human1.81094138
33MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.75384411
34IKZF1_21737484_ChIP-ChIP_HCT116_Human1.73621327
35SRF_21415370_ChIP-Seq_HL-1_Mouse1.73398585
36IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.72143059
37IRF8_22096565_ChIP-ChIP_GC-B_Human1.71934633
38MAF_26560356_Chip-Seq_TH1_Human1.71777270
39UTX_26944678_Chip-Seq_JUKART_Human1.71643199
40ERA_21632823_ChIP-Seq_H3396_Human1.69616024
41RARB_24833708_ChIP-Seq_LIVER_Mouse1.67853958
42CTCF_27219007_Chip-Seq_Bcells_Human1.58988352
43FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.57076187
44FOXP3_21729870_ChIP-Seq_TREG_Human1.56201851
45TAF2_19829295_ChIP-Seq_ESCs_Human1.54771845
46CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.53562115
47FOXP1_21924763_ChIP-Seq_HESCs_Human1.52725767
48ELF1_20517297_ChIP-Seq_JURKAT_Human1.52109697
49BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.50158773
50SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.47509652
51DCP1A_22483619_ChIP-Seq_HELA_Human1.46487627
52TP53_22573176_ChIP-Seq_HFKS_Human1.45446645
53PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.45154127
54CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.44434642
55YY1_21170310_ChIP-Seq_MESCs_Mouse1.44284325
56RXRA_24833708_ChIP-Seq_LIVER_Mouse1.43620842
57CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.42231594
58P53_21459846_ChIP-Seq_SAOS-2_Human1.40006671
59NOTCH1_21737748_ChIP-Seq_TLL_Human1.39138870
60GABP_19822575_ChIP-Seq_HepG2_Human1.38479167
61CTCF_27219007_Chip-Seq_ERYTHROID_Human1.36917215
62DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.36748562
63CTCF_21964334_Chip-Seq_Bcells_Human1.36412085
64SA1_27219007_Chip-Seq_Bcells_Human1.35442443
65OCT4_20526341_ChIP-Seq_ESCs_Human1.34413246
66SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.34193565
67MYC_19829295_ChIP-Seq_ESCs_Human1.32112320
68SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.31970861
69RARA_24833708_ChIP-Seq_LIVER_Mouse1.31803223
70P300_27268052_Chip-Seq_Bcells_Human1.31014502
71PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.30419923
72MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.29695032
73VDR_22108803_ChIP-Seq_LS180_Human1.24091135
74MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.23423760
75EGR1_23403033_ChIP-Seq_LIVER_Mouse1.23418491
76EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.23118351
77MYC_18358816_ChIP-ChIP_MESCs_Mouse1.22508383
78IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.21661734
79TET1_21451524_ChIP-Seq_MESCs_Mouse1.20006805
80CREB1_15753290_ChIP-ChIP_HEK293T_Human1.18097578
81LXR_22292898_ChIP-Seq_THP-1_Human1.17917258
82STAT4_19710469_ChIP-ChIP_TH1__Mouse1.17777272
83STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.16707199
84E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.16177317
85SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.16009755
86EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.15517372
87EWS_26573619_Chip-Seq_HEK293_Human1.15083392
88RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human1.13220864
89SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.11322731
90CTCF_21964334_ChIP-Seq_BJAB-B_Human1.11266570
91SRY_22984422_ChIP-ChIP_TESTIS_Rat1.10820088
92SOX2_21211035_ChIP-Seq_LN229_Human1.10545926
93FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.09708541
94E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.08721103
95CTCF_26484167_Chip-Seq_Bcells_Mouse1.06658145
96BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.03772637
97FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.02508746
98SA1_27219007_Chip-Seq_ERYTHROID_Human1.00690213
99ZNF274_21170338_ChIP-Seq_K562_Hela0.99796328
100RAC3_21632823_ChIP-Seq_H3396_Human0.99124828

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005171_absent_coat_pigmentation6.66833555
2MP0001986_abnormal_taste_sensitivity5.01776822
3MP0005174_abnormal_tail_pigmentation4.90575246
4MP0003136_yellow_coat_color4.06183828
5MP0008875_abnormal_xenobiotic_pharmacok3.58954007
6MP0005423_abnormal_somatic_nervous3.55474134
7MP0005671_abnormal_response_to2.77648241
8MP0005377_hearing/vestibular/ear_phenot2.57173831
9MP0003878_abnormal_ear_physiology2.57173831
10MP0001968_abnormal_touch/_nociception2.51633482
11MP0002638_abnormal_pupillary_reflex2.39304976
12MP0002736_abnormal_nociception_after2.35357941
13MP0003011_delayed_dark_adaptation2.28652318
14MP0001661_extended_life_span2.28148260
15MP0005257_abnormal_intraocular_pressure2.11409602
16MP0005551_abnormal_eye_electrophysiolog2.09248836
17MP0001502_abnormal_circadian_rhythm2.05997803
18MP0005083_abnormal_biliary_tract2.05884530
19MP0005330_cardiomyopathy1.98142657
20MP0002160_abnormal_reproductive_system1.88098273
21MP0001756_abnormal_urination1.85422991
22MP0000015_abnormal_ear_pigmentation1.79100535
23MP0002102_abnormal_ear_morphology1.77446250
24MP0001919_abnormal_reproductive_system1.68275605
25MP0005410_abnormal_fertilization1.67157785
26MP0003806_abnormal_nucleotide_metabolis1.64785689
27MP0008872_abnormal_physiological_respon1.63936153
28MP0001188_hyperpigmentation1.60944786
29MP0003137_abnormal_impulse_conducting1.56437045
30MP0000751_myopathy1.52442782
31MP0004381_abnormal_hair_follicle1.49408076
32MP0009785_altered_susceptibility_to1.47014236
33MP0001905_abnormal_dopamine_level1.46869706
34MP0005253_abnormal_eye_physiology1.45039707
35MP0005332_abnormal_amino_acid1.37971767
36MP0003183_abnormal_peptide_metabolism1.29768122
37MP0006054_spinal_hemorrhage1.29504570
38MP0004215_abnormal_myocardial_fiber1.29237184
39MP0006036_abnormal_mitochondrial_physio1.25407135
40MP0003448_altered_tumor_morphology1.23666723
41MP0000372_irregular_coat_pigmentation1.22899283
42MP0006035_abnormal_mitochondrial_morpho1.20564143
43MP0005389_reproductive_system_phenotype1.14423187
44MP0005365_abnormal_bile_salt1.13647822
45MP0003111_abnormal_nucleus_morphology1.13100316
46MP0002735_abnormal_chemical_nociception1.11806174
47MP0000538_abnormal_urinary_bladder1.08451222
48MP0009643_abnormal_urine_homeostasis1.05151684
49MP0002909_abnormal_adrenal_gland1.01902840
50MP0005670_abnormal_white_adipose0.99808807
51MP0000358_abnormal_cell_content/0.97149561
52MP0001765_abnormal_ion_homeostasis0.93024484
53MP0003045_fibrosis0.91304038
54MP0003195_calcinosis0.90662302
55MP0002095_abnormal_skin_pigmentation0.89968584
56MP0006082_CNS_inflammation0.87839845
57MP0002277_abnormal_respiratory_mucosa0.86439390
58MP0001324_abnormal_eye_pigmentation0.85568867
59MP0001835_abnormal_antigen_presentation0.83745637
60MP0003077_abnormal_cell_cycle0.82358034
61MP0002254_reproductive_system_inflammat0.82024914
62MP0001970_abnormal_pain_threshold0.78925471
63MP0006276_abnormal_autonomic_nervous0.75841959
64MP0003866_abnormal_defecation0.75840922
65MP0001800_abnormal_humoral_immune0.75383574
66MP0002148_abnormal_hypersensitivity_rea0.75260354
67MP0003172_abnormal_lysosome_physiology0.74308220
68MP0002723_abnormal_immune_serum0.72816707
69MP0002933_joint_inflammation0.72232851
70MP0004019_abnormal_vitamin_homeostasis0.71882118
71MP0009333_abnormal_splenocyte_physiolog0.71539078
72MP0002019_abnormal_tumor_incidence0.71479987
73MP0000750_abnormal_muscle_regeneration0.71192898
74MP0005584_abnormal_enzyme/coenzyme_acti0.71075743
75MP0005025_abnormal_response_to0.70733066
76MP0002420_abnormal_adaptive_immunity0.70602834
77MP0010155_abnormal_intestine_physiology0.70477452
78MP0005645_abnormal_hypothalamus_physiol0.69765242
79MP0004957_abnormal_blastocyst_morpholog0.68916309
80MP0010094_abnormal_chromosome_stability0.68061816
81MP0008770_decreased_survivor_rate0.66972952
82MP0001819_abnormal_immune_cell0.66917777
83MP0000367_abnormal_coat/_hair0.66704305
84MP0003786_premature_aging0.65121234
85MP0010386_abnormal_urinary_bladder0.64252790
86MP0002876_abnormal_thyroid_physiology0.64170372
87MP0001984_abnormal_olfaction0.63144478
88MP0002166_altered_tumor_susceptibility0.62548523
89MP0002136_abnormal_kidney_physiology0.61276592
90MP0001529_abnormal_vocalization0.59951255
91MP0001664_abnormal_digestion0.59796245
92MP0001873_stomach_inflammation0.59119419
93MP0005167_abnormal_blood-brain_barrier0.57592523
94MP0002452_abnormal_antigen_presenting0.57173117
95MP0002075_abnormal_coat/hair_pigmentati0.56884529
96MP0004130_abnormal_muscle_cell0.56049460
97MP0000716_abnormal_immune_system0.55830201
98MP0002398_abnormal_bone_marrow0.54980391
99MP0003763_abnormal_thymus_physiology0.54960105
100MP0001929_abnormal_gametogenesis0.54250986

Predicted human phenotypes

RankGene SetZ-score
1Testicular atrophy (HP:0000029)5.43886144
2Attenuation of retinal blood vessels (HP:0007843)5.43615995
3Mesangial abnormality (HP:0001966)5.25007530
4Increased hepatocellular lipid droplets (HP:0006565)5.15475278
5Congenital stationary night blindness (HP:0007642)5.13689929
6Renal Fanconi syndrome (HP:0001994)4.85563552
7Lipid accumulation in hepatocytes (HP:0006561)4.81789974
8Dyschromatopsia (HP:0007641)4.71131579
9Rib fusion (HP:0000902)4.63991316
10Increased intramyocellular lipid droplets (HP:0012240)4.32083651
11Decreased electroretinogram (ERG) amplitude (HP:0000654)4.20779293
12Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)4.12466655
13Prolonged partial thromboplastin time (HP:0003645)3.99026421
14Facial diplegia (HP:0001349)3.94598360
15Decreased central vision (HP:0007663)3.91162739
16Increased muscle lipid content (HP:0009058)3.81558579
17Abnormality of the intrinsic pathway (HP:0010989)3.68911634
18Hypoalbuminemia (HP:0003073)3.56129128
19Abnormal albumin level (HP:0012116)3.56129128
20Exertional dyspnea (HP:0002875)3.54568917
21Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.54481465
22Rectal fistula (HP:0100590)3.48387364
23Rectovaginal fistula (HP:0000143)3.48387364
24Aplasia/Hypoplasia involving the carpal bones (HP:0006502)3.45172029
25Joint hemorrhage (HP:0005261)3.41850629
26Amniotic constriction ring (HP:0009775)3.39596758
27Abnormality of placental membranes (HP:0011409)3.39596758
28Poikiloderma (HP:0001029)3.30701462
29Mitochondrial inheritance (HP:0001427)3.22599098
30Aplastic anemia (HP:0001915)3.17974041
31Choroideremia (HP:0001139)3.15662166
32Popliteal pterygium (HP:0009756)3.09511215
33Facial hemangioma (HP:0000329)3.09152292
34Chorioretinal atrophy (HP:0000533)2.95602440
35Vaginal fistula (HP:0004320)2.94734554
36Aplasia of the musculature (HP:0100854)2.94673646
37Intestinal fistula (HP:0100819)2.94102919
38Hemorrhage of the eye (HP:0011885)2.85378204
39Zonular cataract (HP:0010920)2.80395519
40Akinesia (HP:0002304)2.77362994
41Abnormality of renal resorption (HP:0011038)2.76676584
42Squamous cell carcinoma (HP:0002860)2.69646681
43Respiratory difficulties (HP:0002880)2.65577226
44Myotonia (HP:0002486)2.65348826
45Fetal akinesia sequence (HP:0001989)2.63867051
46Increased CSF lactate (HP:0002490)2.61773774
47Annular pancreas (HP:0001734)2.54485642
48Stomach cancer (HP:0012126)2.48402160
49Patellar aplasia (HP:0006443)2.46473458
50Bony spicule pigmentary retinopathy (HP:0007737)2.45697205
51Aplasia/Hypoplasia involving the musculature (HP:0001460)2.42281379
52Glycosuria (HP:0003076)2.38463066
53Abnormality of urine glucose concentration (HP:0011016)2.38463066
54Abnormality of midbrain morphology (HP:0002418)2.36825559
55Molar tooth sign on MRI (HP:0002419)2.36825559
56Absent thumb (HP:0009777)2.36501464
57Neonatal respiratory distress (HP:0002643)2.36376079
58Aplasia/Hypoplasia of the patella (HP:0006498)2.33314727
59Hypophosphatemic rickets (HP:0004912)2.32128746
60Premature graying of hair (HP:0002216)2.28678198
61Macular degeneration (HP:0000608)2.28348812
62Abnormality of the costochondral junction (HP:0000919)2.25618531
63Abnormal urine phosphate concentration (HP:0012599)2.25018152
64Increased IgM level (HP:0003496)2.24491626
65Hepatocellular necrosis (HP:0001404)2.23778393
66Optic disc pallor (HP:0000543)2.17834376
67Abnormal drinking behavior (HP:0030082)2.17144328
68Polydipsia (HP:0001959)2.17144328
69Type 2 muscle fiber atrophy (HP:0003554)2.16407521
70Delayed epiphyseal ossification (HP:0002663)2.13052125
71Short chin (HP:0000331)2.11601308
72Malignant hyperthermia (HP:0002047)2.10683787
73Abnormality of B cell number (HP:0010975)2.04692176
74Hyperphosphaturia (HP:0003109)2.03155322
75Epiphyseal stippling (HP:0010655)2.02989890
76Long clavicles (HP:0000890)2.02645718
77Anteriorly placed anus (HP:0001545)2.02358339
78Abnormality of T cell number (HP:0011839)1.99377369
79Acute necrotizing encephalopathy (HP:0006965)1.98624326
80Pendular nystagmus (HP:0012043)1.98047140
81Abnormal epiphyseal ossification (HP:0010656)1.96857060
82Hepatic necrosis (HP:0002605)1.94175485
83Ulnar bowing (HP:0003031)1.93938873
84Thin bony cortex (HP:0002753)1.93259182
85Abnormality of the common coagulation pathway (HP:0010990)1.92637497
86Neonatal onset (HP:0003623)1.92401008
87Atrioventricular block (HP:0001678)1.91269123
88Polyuria (HP:0000103)1.89969432
89Muscle fiber atrophy (HP:0100295)1.89231917
90Generalized aminoaciduria (HP:0002909)1.86894407
91IgG deficiency (HP:0004315)1.85592975
92Coronal craniosynostosis (HP:0004440)1.85533293
93Abnormal mitochondria in muscle tissue (HP:0008316)1.83997716
94Abnormality of eosinophils (HP:0001879)1.83482172
95Colon cancer (HP:0003003)1.82378269
96Increased serum lactate (HP:0002151)1.81651675
97Lactic acidosis (HP:0003128)1.80934560
98Elevated erythrocyte sedimentation rate (HP:0003565)1.80650442
99Turricephaly (HP:0000262)1.77639533
100Recurrent cutaneous fungal infections (HP:0011370)1.75231129

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK156.63040787
2KDR3.63055268
3TESK23.60696347
4WNK43.36243789
5MUSK3.29381557
6PINK12.87270642
7TRIM282.58826339
8VRK22.53869158
9TXK2.36711480
10ADRBK22.22634899
11ZAK2.05608437
12EIF2AK32.00873807
13BCKDK1.91409869
14TIE11.80584183
15NUAK11.77993244
16TLK11.71313097
17GRK11.65772676
18BLK1.63664845
19CAMKK21.46884125
20MST41.44215476
21MAP4K11.34572910
22ADRBK11.32735967
23GRK61.32706564
24TAF11.31092882
25ITK1.24747658
26EIF2AK11.20713608
27STK391.18516063
28MAP2K61.15223371
29PASK1.12554786
30FRK1.12112009
31TEC1.11625658
32PDK21.11245931
33TESK11.07481092
34STK161.06965673
35INSRR1.06287476
36CSNK1G31.04881184
37ZAP701.04373702
38VRK11.01249760
39SRPK10.90890490
40CSNK1A1L0.90517236
41CCNB10.87249207
42GRK70.86458218
43GRK50.86423880
44OXSR10.84281949
45WNK30.82287973
46CSK0.79196108
47DAPK10.78282785
48CSNK1G10.74709542
49CSNK1G20.73720308
50BRSK20.73570512
51CAMKK10.69797500
52BMPR1B0.68804240
53LIMK10.65394420
54PRKCQ0.62046795
55SYK0.60491039
56CDK180.60473374
57ACVR1B0.60264190
58PAK10.60022783
59FES0.59614195
60CDK150.58577155
61DYRK20.57364303
62MAP3K120.57358205
63PLK20.56994141
64LYN0.56136235
65AURKA0.55839984
66CHEK20.54441177
67PLK10.53764818
68CDK11A0.53335026
69SIK30.53134713
70RPS6KA50.50113411
71MYLK0.48570645
72BMX0.48514502
73ATR0.45582164
74DAPK20.45562175
75CDK140.43480812
76PIK3CG0.43140643
77IKBKE0.42886865
78BUB10.40698484
79CSNK1D0.40341721
80PAK30.40306572
81LCK0.39218458
82MAP4K20.38696092
83PRKCA0.37831372
84IKBKB0.37515657
85SIK20.36600737
86CDK40.36213170
87PLK30.35672047
88PIK3CA0.34981257
89KIT0.34078411
90IGF1R0.32600125
91PRKCH0.32563699
92JAK30.32446520
93BTK0.32304664
94PRKCD0.31585515
95PTK2B0.30305928
96ROCK10.29954948
97BCR0.29735338
98TAOK30.28821680
99PRKD10.28565836
100NME10.27961374

Predicted pathways (KEGG)

RankGene SetZ-score
1Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001306.40112643
2Terpenoid backbone biosynthesis_Homo sapiens_hsa009004.04076447
3Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006043.83874989
4Primary immunodeficiency_Homo sapiens_hsa053403.78017235
5Proteasome_Homo sapiens_hsa030503.29654956
6Oxidative phosphorylation_Homo sapiens_hsa001902.30849632
7Sulfur relay system_Homo sapiens_hsa041222.17266564
8Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.97683494
9RNA polymerase_Homo sapiens_hsa030201.90663721
10Parkinsons disease_Homo sapiens_hsa050121.88799854
11Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.85536589
12Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.81205667
13Graft-versus-host disease_Homo sapiens_hsa053321.62987631
14Hematopoietic cell lineage_Homo sapiens_hsa046401.61329284
15Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.55986021
16Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.51031986
17Fanconi anemia pathway_Homo sapiens_hsa034601.50997534
18Antigen processing and presentation_Homo sapiens_hsa046121.48266928
19Phototransduction_Homo sapiens_hsa047441.46846895
20Nitrogen metabolism_Homo sapiens_hsa009101.42586055
21Glycosaminoglycan degradation_Homo sapiens_hsa005311.37131666
22Homologous recombination_Homo sapiens_hsa034401.32349643
23Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.27203775
24Steroid biosynthesis_Homo sapiens_hsa001001.24499195
25Huntingtons disease_Homo sapiens_hsa050161.23553594
26Caffeine metabolism_Homo sapiens_hsa002321.21373709
27Allograft rejection_Homo sapiens_hsa053301.20110369
28Autoimmune thyroid disease_Homo sapiens_hsa053201.19969422
29Base excision repair_Homo sapiens_hsa034101.18701504
30Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.15743296
31Alzheimers disease_Homo sapiens_hsa050101.10552798
32Basal transcription factors_Homo sapiens_hsa030221.08677251
33Sphingolipid metabolism_Homo sapiens_hsa006001.07699109
34Chemical carcinogenesis_Homo sapiens_hsa052041.06446445
35Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.06153073
36Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.05564445
37Type I diabetes mellitus_Homo sapiens_hsa049401.04863329
38Fructose and mannose metabolism_Homo sapiens_hsa000511.03530404
39Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.02356753
40Pyruvate metabolism_Homo sapiens_hsa006200.98350504
412-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.98032020
42Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.93488848
43Protein export_Homo sapiens_hsa030600.91501390
44Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.89541186
45Glutathione metabolism_Homo sapiens_hsa004800.86747750
46Circadian rhythm_Homo sapiens_hsa047100.86246153
47Tryptophan metabolism_Homo sapiens_hsa003800.85633270
48Steroid hormone biosynthesis_Homo sapiens_hsa001400.83104319
49Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.80428659
50T cell receptor signaling pathway_Homo sapiens_hsa046600.80374058
51Pyrimidine metabolism_Homo sapiens_hsa002400.79760234
52Rheumatoid arthritis_Homo sapiens_hsa053230.78095904
53Primary bile acid biosynthesis_Homo sapiens_hsa001200.76801079
54Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.75265603
55Taste transduction_Homo sapiens_hsa047420.73019820
56Cardiac muscle contraction_Homo sapiens_hsa042600.72722535
57Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.72393523
58Maturity onset diabetes of the young_Homo sapiens_hsa049500.72267968
59Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.71770445
60Sulfur metabolism_Homo sapiens_hsa009200.71509654
61Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.71149493
62Peroxisome_Homo sapiens_hsa041460.69534997
63Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.69494870
64Linoleic acid metabolism_Homo sapiens_hsa005910.65784771
65Intestinal immune network for IgA production_Homo sapiens_hsa046720.63389417
66Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.62637188
67Purine metabolism_Homo sapiens_hsa002300.61863813
68Metabolic pathways_Homo sapiens_hsa011000.59944774
69alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.58740180
70DNA replication_Homo sapiens_hsa030300.58633656
71Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.57679215
72Hedgehog signaling pathway_Homo sapiens_hsa043400.55736138
73Fatty acid degradation_Homo sapiens_hsa000710.52286862
74Retinol metabolism_Homo sapiens_hsa008300.51774392
75One carbon pool by folate_Homo sapiens_hsa006700.51665179
76RNA degradation_Homo sapiens_hsa030180.51394097
77Non-homologous end-joining_Homo sapiens_hsa034500.50855739
78Nicotine addiction_Homo sapiens_hsa050330.50620948
79Systemic lupus erythematosus_Homo sapiens_hsa053220.47924644
80Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.47137746
81Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.46761011
82Butanoate metabolism_Homo sapiens_hsa006500.44589903
83Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.42535582
84Salmonella infection_Homo sapiens_hsa051320.41104418
85Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.39390745
86NF-kappa B signaling pathway_Homo sapiens_hsa040640.39133869
87Ovarian steroidogenesis_Homo sapiens_hsa049130.32722624
88Mineral absorption_Homo sapiens_hsa049780.31921170
89Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.31880360
90N-Glycan biosynthesis_Homo sapiens_hsa005100.29251896
91Fat digestion and absorption_Homo sapiens_hsa049750.28915944
92NOD-like receptor signaling pathway_Homo sapiens_hsa046210.28801377
93Drug metabolism - other enzymes_Homo sapiens_hsa009830.28700520
94Vitamin digestion and absorption_Homo sapiens_hsa049770.28548586
95Calcium signaling pathway_Homo sapiens_hsa040200.27361884
96Nucleotide excision repair_Homo sapiens_hsa034200.27125861
97Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.26719936
98Biosynthesis of amino acids_Homo sapiens_hsa012300.25225277
99Measles_Homo sapiens_hsa051620.24860267
100Fatty acid metabolism_Homo sapiens_hsa012120.24603193

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »