FERMT2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein heterotrimerization (GO:0070208)4.05679979
2endodermal cell differentiation (GO:0035987)3.85335566
3L-phenylalanine catabolic process (GO:0006559)3.73672578
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.73672578
5sequestering of extracellular ligand from receptor (GO:0035581)3.71131487
6negative regulation of fibrinolysis (GO:0051918)3.67461475
7notochord development (GO:0030903)3.55513863
8erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.55004118
9L-phenylalanine metabolic process (GO:0006558)3.55004118
10alpha-linolenic acid metabolic process (GO:0036109)3.44391445
11negative regulation of chondrocyte differentiation (GO:0032331)3.36011862
12kidney mesenchyme development (GO:0072074)3.32820294
13anterior/posterior axis specification, embryo (GO:0008595)3.31441615
14cell adhesion mediated by integrin (GO:0033627)3.25614421
15cell migration involved in heart development (GO:0060973)3.23892634
16regulation of fibrinolysis (GO:0051917)3.19462860
17mesenchymal-epithelial cell signaling (GO:0060638)3.18982968
18regulation of transforming growth factor beta2 production (GO:0032909)3.17741524
19metanephric mesenchyme development (GO:0072075)3.17123176
20lysine catabolic process (GO:0006554)3.10251118
21lysine metabolic process (GO:0006553)3.10251118
22gap junction assembly (GO:0016264)3.09473672
23positive regulation of fatty acid beta-oxidation (GO:0032000)3.07817415
24glyoxylate metabolic process (GO:0046487)3.06360900
25bone trabecula formation (GO:0060346)3.06137131
26extracellular matrix assembly (GO:0085029)3.03978190
27epoxygenase P450 pathway (GO:0019373)3.03671483
28extracellular fibril organization (GO:0043206)3.03088232
29planar cell polarity pathway involved in neural tube closure (GO:0090179)2.97466682
30skin morphogenesis (GO:0043589)2.93104851
31fatty acid transmembrane transport (GO:1902001)2.90581797
32aspartate family amino acid catabolic process (GO:0009068)2.90182122
33retina vasculature morphogenesis in camera-type eye (GO:0061299)2.89042782
34wound healing, spreading of epidermal cells (GO:0035313)2.88868279
35positive regulation of SMAD protein import into nucleus (GO:0060391)2.87743877
36carnitine shuttle (GO:0006853)2.87304655
37regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.85645776
38cardiac myofibril assembly (GO:0055003)2.85614008
39acetyl-CoA metabolic process (GO:0006084)2.83536588
40protein localization to cell surface (GO:0034394)2.81230103
41regulation of plasminogen activation (GO:0010755)2.80537980
42triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.78791570
43regulation of cardioblast differentiation (GO:0051890)2.78334915
44regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.78275579
45* substrate adhesion-dependent cell spreading (GO:0034446)2.78270032
46ventricular cardiac muscle cell development (GO:0055015)2.78264082
47positive regulation of fatty acid oxidation (GO:0046321)2.78198786
48aromatic amino acid family catabolic process (GO:0009074)2.75610800
49dermatan sulfate biosynthetic process (GO:0030208)2.74641630
50regulation of protein activation cascade (GO:2000257)2.74454002
51regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.74131511
52bile acid biosynthetic process (GO:0006699)2.72141952
53plasma membrane repair (GO:0001778)2.71849890
54heart trabecula formation (GO:0060347)2.70777348
55negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.70266494
56negative regulation of cartilage development (GO:0061037)2.69900190
57actin-myosin filament sliding (GO:0033275)2.69745805
58muscle filament sliding (GO:0030049)2.69745805
59glomerular visceral epithelial cell development (GO:0072015)2.67873084
60collagen metabolic process (GO:0032963)2.67701329
61peptidyl-glutamic acid carboxylation (GO:0017187)2.66958992
62protein carboxylation (GO:0018214)2.66958992
63cell migration involved in sprouting angiogenesis (GO:0002042)2.66814072
64endocardial cushion development (GO:0003197)2.66420488
65sarcomere organization (GO:0045214)2.65813730
66endothelial cell morphogenesis (GO:0001886)2.65771211
67regulation of complement activation (GO:0030449)2.64732625
68sulfur amino acid catabolic process (GO:0000098)2.64504638
69axon extension involved in axon guidance (GO:0048846)2.64065224
70neuron projection extension involved in neuron projection guidance (GO:1902284)2.64065224
71outer ear morphogenesis (GO:0042473)2.61159252
72vascular endothelial growth factor signaling pathway (GO:0038084)2.59351565
73negative regulation of BMP signaling pathway (GO:0030514)2.59343533
74cysteine metabolic process (GO:0006534)2.59328123
75chondrocyte development (GO:0002063)2.58092038
76branching involved in salivary gland morphogenesis (GO:0060445)2.56329552
77fatty acid beta-oxidation (GO:0006635)2.55874421
78positive regulation of endothelial cell apoptotic process (GO:2000353)2.55573604
79glomerular basement membrane development (GO:0032836)2.55437675
80positive regulation of cardiac muscle cell proliferation (GO:0060045)2.54465834
81glomerular filtration (GO:0003094)2.54430122
82negative regulation of embryonic development (GO:0045992)2.54347228
83basement membrane organization (GO:0071711)2.53547747
84creatine metabolic process (GO:0006600)2.52847682
85renal filtration (GO:0097205)2.51379813
86negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.51195870
87multicellular organismal macromolecule metabolic process (GO:0044259)2.50285379
88chondrocyte proliferation (GO:0035988)2.49505314
89actin-mediated cell contraction (GO:0070252)2.49236997
90convergent extension (GO:0060026)2.49191057
91regulation of skeletal muscle contraction (GO:0014819)2.49030860
92regulation of fatty acid beta-oxidation (GO:0031998)2.48928364
93short-chain fatty acid metabolic process (GO:0046459)2.48132920
94positive regulation of catenin import into nucleus (GO:0035413)2.47700949
95regulation of fatty acid oxidation (GO:0046320)2.46399385
96collagen catabolic process (GO:0030574)2.46091668
97collagen fibril organization (GO:0030199)2.46022919
98glutamate metabolic process (GO:0006536)2.45268166
99complement activation, alternative pathway (GO:0006957)2.44429132
100myofibril assembly (GO:0030239)2.44235500
101dermatan sulfate metabolic process (GO:0030205)2.43954841
102G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.42892455
103central nervous system myelination (GO:0022010)2.42711537
104axon ensheathment in central nervous system (GO:0032291)2.42711537
105fibrinolysis (GO:0042730)2.42465473
106midgut development (GO:0007494)2.41831731
107substrate-dependent cell migration (GO:0006929)2.41431516
108negative regulation of protein localization to cell surface (GO:2000009)2.41087692
109coenzyme catabolic process (GO:0009109)2.41071052
110type B pancreatic cell proliferation (GO:0044342)2.41042690
111regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.40449602
112cellular modified amino acid catabolic process (GO:0042219)2.40008871
113negative regulation of smooth muscle cell migration (GO:0014912)2.39586177
114ethanol oxidation (GO:0006069)2.38834477
115homocysteine metabolic process (GO:0050667)2.38820934
116multicellular organismal metabolic process (GO:0044236)2.38767134
117kynurenine metabolic process (GO:0070189)2.38583806
118positive regulation of cardiac muscle tissue development (GO:0055025)2.38317880
119negative regulation of potassium ion transmembrane transport (GO:1901380)2.38102213
120neural crest cell development (GO:0014032)2.38099241
121Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.38078717
122response to mercury ion (GO:0046689)2.37725332
123regulation of cell fate specification (GO:0042659)2.37003343
124alpha-amino acid catabolic process (GO:1901606)2.35939516
125regulation of SMAD protein import into nucleus (GO:0060390)2.35281010
126branched-chain amino acid catabolic process (GO:0009083)2.35188956
127positive regulation of osteoblast proliferation (GO:0033690)2.35166275
128peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.35036994
129regulation of cardiac muscle tissue development (GO:0055024)2.34856437
130lipid oxidation (GO:0034440)2.34799722
131extracellular matrix disassembly (GO:0022617)2.34670934
132regulation of gastrulation (GO:0010470)2.34654579
133peripheral nervous system axon ensheathment (GO:0032292)2.34422439
134myelination in peripheral nervous system (GO:0022011)2.34422439
135fatty acid oxidation (GO:0019395)2.34325065
136epithelial cell-cell adhesion (GO:0090136)2.34216904
137cochlea morphogenesis (GO:0090103)2.33654668
138regulation of integrin-mediated signaling pathway (GO:2001044)2.33640948
139negative regulation of cardiac muscle tissue development (GO:0055026)2.33510078
140plasma lipoprotein particle clearance (GO:0034381)2.32718055
141non-canonical Wnt signaling pathway (GO:0035567)2.32607067
142dicarboxylic acid biosynthetic process (GO:0043650)2.32534782
143thioester biosynthetic process (GO:0035384)2.32412608
144acyl-CoA biosynthetic process (GO:0071616)2.32412608
145* adherens junction assembly (GO:0034333)2.32093143
146lymphangiogenesis (GO:0001946)2.31879647
147fibril organization (GO:0097435)2.31293919
148cellular ketone body metabolic process (GO:0046950)2.31061295
149trabecula formation (GO:0060343)2.30971389
150paraxial mesoderm development (GO:0048339)2.30915251
151positive regulation of cardiac muscle tissue growth (GO:0055023)2.30435411
152extracellular matrix organization (GO:0030198)2.30143945
153negative regulation of axon extension involved in axon guidance (GO:0048843)2.29867960
154negative regulation of protein activation cascade (GO:2000258)2.29642740
155regulation of axon extension involved in axon guidance (GO:0048841)2.29364017
156regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.29361495
157extracellular structure organization (GO:0043062)2.29284628
158cellular amino acid catabolic process (GO:0009063)2.29025763
159regulation of establishment of planar polarity (GO:0090175)2.28979261
160serine family amino acid catabolic process (GO:0009071)2.28758632
161regulation of cholesterol homeostasis (GO:2000188)2.28190413
162fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.27442509
163amino-acid betaine metabolic process (GO:0006577)2.27384625
164fatty acid catabolic process (GO:0009062)2.27192101
165high-density lipoprotein particle remodeling (GO:0034375)2.26340017
166cell migration involved in gastrulation (GO:0042074)2.25988497
167muscle cell migration (GO:0014812)2.25149330
1682-oxoglutarate metabolic process (GO:0006103)2.25075786
169tyrosine metabolic process (GO:0006570)2.24864423
1704-hydroxyproline metabolic process (GO:0019471)2.24856130
171smooth muscle tissue development (GO:0048745)2.24673550
172hippo signaling (GO:0035329)2.24630575
173regulation of triglyceride catabolic process (GO:0010896)2.24177787
174glomerular epithelial cell development (GO:0072310)2.23740397
175* cell-substrate junction assembly (GO:0007044)2.22992419
176wound healing, spreading of cells (GO:0044319)2.22835303
177cellular response to vitamin (GO:0071295)2.22630315
178regulation of sequestering of triglyceride (GO:0010889)2.22467400
179regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.22403688
180biotin metabolic process (GO:0006768)2.22022426
181acylglycerol homeostasis (GO:0055090)2.21882008
182triglyceride homeostasis (GO:0070328)2.21882008
183multicellular organismal catabolic process (GO:0044243)2.20731083
184embryonic foregut morphogenesis (GO:0048617)2.20650878

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.73446960
2TRIM28_21343339_ChIP-Seq_HEK293_Human3.83632582
3PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.82213993
4* RXR_22158963_ChIP-Seq_LIVER_Mouse3.21039711
5* LXR_22158963_ChIP-Seq_LIVER_Mouse2.88492402
6CLOCK_20551151_ChIP-Seq_293T_Human2.87501706
7PPARA_22158963_ChIP-Seq_LIVER_Mouse2.67693941
8RARG_19884340_ChIP-ChIP_MEFs_Mouse2.53518075
9PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.45116081
10EP300_21415370_ChIP-Seq_HL-1_Mouse2.39693544
11SALL1_21062744_ChIP-ChIP_HESCs_Human2.32593113
12NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.28967412
13AR_21909140_ChIP-Seq_LNCAP_Human2.07682388
14FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.07123158
15RBPJ_22232070_ChIP-Seq_NCS_Mouse2.04616111
16TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.02986593
17HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.97744165
18ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.96804730
19ESR2_21235772_ChIP-Seq_MCF-7_Human1.94170874
20NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.90772160
21SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.86823859
22SMAD_19615063_ChIP-ChIP_OVARY_Human1.85388773
23TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.79617330
24CDX2_19796622_ChIP-Seq_MESCs_Mouse1.77093026
25SALL4_18804426_ChIP-ChIP_XEN_Mouse1.70772463
26WT1_19549856_ChIP-ChIP_CCG9911_Human1.65207714
27KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.64371764
28KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.64371764
29KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.64371764
30ESR1_20079471_ChIP-ChIP_T-47D_Human1.64363708
31EGR1_23403033_ChIP-Seq_LIVER_Mouse1.60711864
32NRF2_20460467_ChIP-Seq_MEFs_Mouse1.56994145
33NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.56994145
34EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.56807565
35SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.53668610
36EED_16625203_ChIP-ChIP_MESCs_Mouse1.51405484
37TBX3_20139965_ChIP-Seq_ESCs_Mouse1.50407409
38TBX3_20139965_ChIP-Seq_MESCs_Mouse1.50011079
39CJUN_26792858_Chip-Seq_BT549_Human1.49713058
40RNF2_18974828_ChIP-Seq_MESCs_Mouse1.49554945
41EZH2_18974828_ChIP-Seq_MESCs_Mouse1.49554945
42ESR1_21235772_ChIP-Seq_MCF-7_Human1.48410924
43GBX2_23144817_ChIP-Seq_PC3_Human1.47550443
44TBX20_22328084_ChIP-Seq_HEART_Mouse1.44979883
45TBX20_22080862_ChIP-Seq_HEART_Mouse1.44979883
46TP63_17297297_ChIP-ChIP_HaCaT_Human1.43648794
47PPAR_26484153_Chip-Seq_NCI-H1993_Human1.41560018
48SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.41528603
49ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.39346624
50TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.37075066
51ZNF217_24962896_ChIP-Seq_MCF-7_Human1.31278359
52* FOXA2_19822575_ChIP-Seq_HepG2_Human1.30118813
53WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.29375966
54SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.26023004
55FOXO3_23340844_ChIP-Seq_DLD1_Human1.24798030
56HIF1A_21447827_ChIP-Seq_MCF-7_Human1.21397897
57CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.21364242
58SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.20719012
59POU5F1_16153702_ChIP-ChIP_HESCs_Human1.20058631
60PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.19962117
61MTF2_20144788_ChIP-Seq_MESCs_Mouse1.16656981
62RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.16619594
63SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.16428294
64FOXM1_23109430_ChIP-Seq_U2OS_Human1.16373405
65ESR1_15608294_ChIP-ChIP_MCF-7_Human1.16145650
66ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.16061703
67BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.15914383
68GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.15859544
69ISL1_27105846_Chip-Seq_CPCs_Mouse1.15323702
70E2F7_22180533_ChIP-Seq_HELA_Human1.14695326
71STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.14693496
72* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.14139233
73TCF3_18692474_ChIP-Seq_MESCs_Mouse1.14095201
74* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12903577
75CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.11837089
76ZNF263_19887448_ChIP-Seq_K562_Human1.11657809
77* PIAS1_25552417_ChIP-Seq_VCAP_Human1.10340783
78SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.10015450
79EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.10006770
80TP53_16413492_ChIP-PET_HCT116_Human1.09388534
81YAP1_20516196_ChIP-Seq_MESCs_Mouse1.09262333
82TP53_20018659_ChIP-ChIP_R1E_Mouse1.08529763
83AR_21572438_ChIP-Seq_LNCaP_Human1.07470479
84NANOG_16153702_ChIP-ChIP_HESCs_Human1.06690576
85ERG_21242973_ChIP-ChIP_JURKAT_Human1.06199373
86SMAD3_21741376_ChIP-Seq_HESCs_Human1.06070846
87CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.06048446
88TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.05857498
89MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.05109569
90PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.04939216
91ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.04927108
92EZH2_27304074_Chip-Seq_ESCs_Mouse1.04706432
93TCF3_18692474_ChIP-Seq_MEFs_Mouse1.04623337
94JARID2_20075857_ChIP-Seq_MESCs_Mouse1.04176587
95TP53_18474530_ChIP-ChIP_U2OS_Human1.03574931
96SOX9_26525672_Chip-Seq_HEART_Mouse1.03139441
97NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.02416293
98ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.01531652
99ZFP57_27257070_Chip-Seq_ESCs_Mouse1.01214240
100SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.01033183
101SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.01033183
102SOX17_20123909_ChIP-Seq_XEN_Mouse1.00828309
103NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.00514037
104SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.00108735
105ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.98443920
106* WT1_25993318_ChIP-Seq_PODOCYTE_Human0.98353110
107RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.98243136
108SA1_22415368_ChIP-Seq_MEFs_Mouse0.98168930
109CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.98166659
110SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.96738590
111PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.96367495
112SMAD3_21741376_ChIP-Seq_EPCs_Human0.95790506
113NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.94788351
114PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.94398803
115SMAD4_21799915_ChIP-Seq_A2780_Human0.94213824
116SOX2_20726797_ChIP-Seq_SW620_Human0.90276839
117SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.89721583
118AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.89568360
119JARID2_20064375_ChIP-Seq_MESCs_Mouse0.88864293
120POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.88486225
121PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.88296429
122* TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.88199453
123P300_27058665_Chip-Seq_ZR-75-30cells_Human0.87694144
124TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.86952346
125RNF2_27304074_Chip-Seq_ESCs_Mouse0.86951038
126SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.86332093
127* BRD4_25478319_ChIP-Seq_HGPS_Human0.86230154
128ZFP281_18757296_ChIP-ChIP_E14_Mouse0.85829273
129* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.85757781
130SOX9_24532713_ChIP-Seq_HFSC_Mouse0.85409846
131AHR_22903824_ChIP-Seq_MCF-7_Human0.83837574
132* BCAT_22108803_ChIP-Seq_LS180_Human0.83395974
133NFIB_24661679_ChIP-Seq_LUNG_Mouse0.82582382
134OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.81872919
135SMAD4_21741376_ChIP-Seq_HESCs_Human0.81635104
136NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.81360592
137EZH2_27294783_Chip-Seq_ESCs_Mouse0.80827451

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen3.88766402
2MP0002139_abnormal_hepatobiliary_system2.95320060
3MP0004272_abnormal_basement_membrane2.89431772
4MP0005360_urolithiasis2.78312808
5MP0003705_abnormal_hypodermis_morpholog2.69624244
6MP0003806_abnormal_nucleotide_metabolis2.60846472
7MP0004084_abnormal_cardiac_muscle2.50137529
8MP0003941_abnormal_skin_development2.45432694
9MP0010368_abnormal_lymphatic_system2.43716006
10MP0003279_aneurysm2.27377151
11MP0009384_cardiac_valve_regurgitation2.20845147
12MP0005275_abnormal_skin_tensile2.20689969
13MP0005257_abnormal_intraocular_pressure2.20089142
14MP0005085_abnormal_gallbladder_physiolo2.18028839
15MP0005623_abnormal_meninges_morphology2.17554744
16MP0000751_myopathy2.12389778
17MP0005503_abnormal_tendon_morphology2.12129752
18MP0004036_abnormal_muscle_relaxation2.09087996
19MP0006054_spinal_hemorrhage1.99361263
20MP0002837_dystrophic_cardiac_calcinosis1.94448584
21MP0005365_abnormal_bile_salt1.91195071
22MP0000749_muscle_degeneration1.90657504
23MP0003950_abnormal_plasma_membrane1.80448007
24MP0005330_cardiomyopathy1.78698955
25MP0006138_congestive_heart_failure1.70332753
26MP0004087_abnormal_muscle_fiber1.62448608
27MP0010352_gastrointestinal_tract_polyps1.61991727
28MP0005620_abnormal_muscle_contractility1.61012835
29MP0004215_abnormal_myocardial_fiber1.57141151
30MP0001958_emphysema1.55909369
31MP0008775_abnormal_heart_ventricle1.54601503
32MP0004145_abnormal_muscle_electrophysio1.50447588
33MP0002972_abnormal_cardiac_muscle1.50400662
34MP0003252_abnormal_bile_duct1.47651352
35MP0000750_abnormal_muscle_regeneration1.45712899
36MP0005670_abnormal_white_adipose1.45527883
37MP0002108_abnormal_muscle_morphology1.41341105
38MP0004130_abnormal_muscle_cell1.41075084
39MP0002295_abnormal_pulmonary_circulatio1.40923748
40MP0000747_muscle_weakness1.39468568
41MP0008875_abnormal_xenobiotic_pharmacok1.39401850
42MP0001879_abnormal_lymphatic_vessel1.36677431
43MP0005332_abnormal_amino_acid1.35132308
44MP0009053_abnormal_anal_canal1.34589805
45MP0000013_abnormal_adipose_tissue1.33169807
46MP0010030_abnormal_orbit_morphology1.32884085
47MP0002060_abnormal_skin_morphology1.31404632
48MP0000428_abnormal_craniofacial_morphol1.31173959
49MP0009250_abnormal_appendicular_skeleto1.30862811
50MP0001542_abnormal_bone_strength1.29614601
51MP0002269_muscular_atrophy1.27794218
52MP0005666_abnormal_adipose_tissue1.26416008
53MP0010630_abnormal_cardiac_muscle1.25981893
54MP0010329_abnormal_lipoprotein_level1.22925453
55MP0005385_cardiovascular_system_phenoty1.21575202
56MP0001544_abnormal_cardiovascular_syste1.21575202
57MP0000049_abnormal_middle_ear1.20272860
58MP0002697_abnormal_eye_size1.19561640
59MP0004233_abnormal_muscle_weight1.13671163
60MP0000759_abnormal_skeletal_muscle1.12525338
61MP0003137_abnormal_impulse_conducting1.12138472
62MP0000534_abnormal_ureter_morphology1.10245975
63MP0005369_muscle_phenotype1.09300807
64MP0000733_abnormal_muscle_development1.08760298
65MP0003385_abnormal_body_wall1.08438887
66MP0000767_abnormal_smooth_muscle1.07971599
67MP0003890_abnormal_embryonic-extraembry1.06811787
68MP0009840_abnormal_foam_cell1.06738664
69MP0002106_abnormal_muscle_physiology1.06366224
70MP0005083_abnormal_biliary_tract1.06185728
71MP0005595_abnormal_vascular_smooth1.06097054
72MP0003283_abnormal_digestive_organ1.05657819
73MP0005375_adipose_tissue_phenotype1.04768001
74MP0001299_abnormal_eye_distance/1.03975963
75* MP0003566_abnormal_cell_adhesion1.03455175
76MP0000537_abnormal_urethra_morphology1.01324609
77MP0003646_muscle_fatigue1.01304844
78MP0003935_abnormal_craniofacial_develop1.00570314
79MP0000003_abnormal_adipose_tissue1.00486058
80MP0004185_abnormal_adipocyte_glucose1.00346224
81MP0003942_abnormal_urinary_system0.99149717
82MP0003195_calcinosis0.99099212
83MP0002254_reproductive_system_inflammat0.98812079
84MP0003329_amyloid_beta_deposits0.98538406
85MP0009780_abnormal_chondrocyte_physiolo0.97728165
86MP0000432_abnormal_head_morphology0.96935910
87MP0005508_abnormal_skeleton_morphology0.96926075
88MP0002128_abnormal_blood_circulation0.96073415
89MP0003091_abnormal_cell_migration0.95420654
90MP0002233_abnormal_nose_morphology0.93962766
91MP0002127_abnormal_cardiovascular_syste0.93819822
92MP0001661_extended_life_span0.92969790
93MP0001915_intracranial_hemorrhage0.92882339
94MP0004085_abnormal_heartbeat0.92182541
95MP0003937_abnormal_limbs/digits/tail_de0.91607919
96MP0002118_abnormal_lipid_homeostasis0.91343473
97MP0004484_altered_response_of0.90923197
98MP0001243_abnormal_dermal_layer0.90281097
99MP0005171_absent_coat_pigmentation0.88995069
100MP0005197_abnormal_uvea_morphology0.88954619
101MP0002249_abnormal_larynx_morphology0.88730664
102MP0003115_abnormal_respiratory_system0.88668900
103MP0004858_abnormal_nervous_system0.85653875
104MP0000762_abnormal_tongue_morphology0.85342493
105MP0002896_abnormal_bone_mineralization0.85169789
106MP0003119_abnormal_digestive_system0.83873452
107MP0002925_abnormal_cardiovascular_devel0.83518178
108MP0005248_abnormal_Harderian_gland0.83494093
109MP0002282_abnormal_trachea_morphology0.82933877
110MP0001177_atelectasis0.81981346
111* MP0002084_abnormal_developmental_patter0.81943817
112* MP0002085_abnormal_embryonic_tissue0.79732692
113MP0002092_abnormal_eye_morphology0.79705426
114MP0008932_abnormal_embryonic_tissue0.79401197
115MP0001286_abnormal_eye_development0.78672161
116MP0002932_abnormal_joint_morphology0.78365967
117MP0005165_increased_susceptibility_to0.77753732
118MP0003690_abnormal_glial_cell0.76527189
119MP0005023_abnormal_wound_healing0.76196133
120MP0002116_abnormal_craniofacial_bone0.75201074
121MP0001614_abnormal_blood_vessel0.74509039
122MP0001293_anophthalmia0.74161359
123MP0000163_abnormal_cartilage_morphology0.73937999
124MP0002877_abnormal_melanocyte_morpholog0.73602752
125MP0002111_abnormal_tail_morphology0.72281716
126MP0001849_ear_inflammation0.72073410
127MP0000462_abnormal_digestive_system0.71386918
128MP0002114_abnormal_axial_skeleton0.70902054
129MP0002115_abnormal_skeleton_extremities0.70207958
130MP0000266_abnormal_heart_morphology0.70107623
131MP0002971_abnormal_brown_adipose0.70019635
132MP0003755_abnormal_palate_morphology0.69370421
133MP0003567_abnormal_fetal_cardiomyocyte0.69288693
134MP0000230_abnormal_systemic_arterial0.68592580
135MP0005167_abnormal_blood-brain_barrier0.68472425
136MP0004885_abnormal_endolymph0.68458540
137MP0005388_respiratory_system_phenotype0.67527722
138MP0002133_abnormal_respiratory_system0.67527722

Predicted human phenotypes

RankGene SetZ-score
1Premature rupture of membranes (HP:0001788)4.30445328
2Protrusio acetabuli (HP:0003179)4.05979235
3Vascular tortuosity (HP:0004948)3.70263293
4Deep venous thrombosis (HP:0002625)3.67560923
5Muscle fiber splitting (HP:0003555)3.64330580
6Arterial tortuosity (HP:0005116)3.42617699
7Hyporeflexia of lower limbs (HP:0002600)3.30187316
8Broad metatarsal (HP:0001783)3.24361239
9Intrahepatic cholestasis (HP:0001406)3.16537563
10Type 1 muscle fiber predominance (HP:0003803)3.02223613
11Xanthomatosis (HP:0000991)2.99829725
12Exercise-induced muscle cramps (HP:0003710)2.94607529
13Shallow orbits (HP:0000586)2.83155862
14Increased connective tissue (HP:0009025)2.82528101
15Fragile skin (HP:0001030)2.82317680
16Right ventricular cardiomyopathy (HP:0011663)2.81168338
17Hypoalphalipoproteinemia (HP:0003233)2.80342069
18Aortic dissection (HP:0002647)2.67798512
19Bowel diverticulosis (HP:0005222)2.67551811
20Genu recurvatum (HP:0002816)2.65914596
21Exercise-induced myalgia (HP:0003738)2.65829352
22Sudden death (HP:0001699)2.61429101
23Round ear (HP:0100830)2.54940966
24Dilatation of the ascending aorta (HP:0005111)2.48298977
25Difficulty running (HP:0009046)2.47133878
26Abnormality of aromatic amino acid family metabolism (HP:0004338)2.46766240
27Spinal rigidity (HP:0003306)2.45204741
28Abnormality of glycine metabolism (HP:0010895)2.43577242
29Abnormality of serine family amino acid metabolism (HP:0010894)2.43577242
30Short hallux (HP:0010109)2.42128863
31Abnormality of the calf musculature (HP:0001430)2.40545782
32Myoglobinuria (HP:0002913)2.39250448
33Hyperlipoproteinemia (HP:0010980)2.36280230
34Ankle contracture (HP:0006466)2.32743758
35Hyperglycinuria (HP:0003108)2.32205113
36Hypolipoproteinemia (HP:0010981)2.31247668
37Increased variability in muscle fiber diameter (HP:0003557)2.29953894
38Aortic aneurysm (HP:0004942)2.29562936
39Aplasia involving bones of the extremities (HP:0009825)2.29097845
40Aplasia involving bones of the upper limbs (HP:0009823)2.29097845
41Aplasia of the phalanges of the hand (HP:0009802)2.29097845
42Hypoglycemic coma (HP:0001325)2.28641074
43Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.28598516
44Coronal craniosynostosis (HP:0004440)2.28308981
45Back pain (HP:0003418)2.25576878
46Muscle fiber inclusion bodies (HP:0100299)2.25273239
47Aplasia/Hypoplasia of the hallux (HP:0008362)2.24599738
48Cervical subluxation (HP:0003308)2.23929725
49Ectopia lentis (HP:0001083)2.23402773
50Renal duplication (HP:0000075)2.22714396
51Ventricular tachycardia (HP:0004756)2.22447173
52EMG: myopathic abnormalities (HP:0003458)2.21778179
53Hyperglycinemia (HP:0002154)2.21736890
54Cerebral aneurysm (HP:0004944)2.20426414
55Aortic regurgitation (HP:0001659)2.19178367
56Hypoplastic ischia (HP:0003175)2.17959121
57Hyperammonemia (HP:0001987)2.17740186
58Ulnar bowing (HP:0003031)2.17123243
59Joint laxity (HP:0001388)2.15471270
60Mitral regurgitation (HP:0001653)2.14269954
61Mesomelia (HP:0003027)2.13521594
62Scapular winging (HP:0003691)2.10715980
63Wrist flexion contracture (HP:0001239)2.09438083
64Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.09060992
65Abnormality of the ischium (HP:0003174)2.08676662
66Osteolytic defects of the hand bones (HP:0009699)2.08142835
67Osteolytic defects of the phalanges of the hand (HP:0009771)2.08142835
68Slender build (HP:0001533)2.07606279
69Lipoatrophy (HP:0100578)2.06414978
70Muscle hypertrophy of the lower extremities (HP:0008968)2.05092515
71Biconcave vertebral bodies (HP:0004586)2.03934014
72Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.03890726
73Calf muscle hypertrophy (HP:0008981)2.02986318
74Infantile muscular hypotonia (HP:0008947)2.01249815
75Breech presentation (HP:0001623)2.00172813
76Ketosis (HP:0001946)2.00146439
77Soft skin (HP:0000977)1.97309969
78Complement deficiency (HP:0004431)1.96682083
79Epidermoid cyst (HP:0200040)1.96296768
80Atrial fibrillation (HP:0005110)1.94944952
81Peritonitis (HP:0002586)1.94943059
82Camptodactyly of toe (HP:0001836)1.93915426
83Limited hip movement (HP:0008800)1.93606935
84Broad long bones (HP:0005622)1.93453982
85Abnormality of skeletal muscle fiber size (HP:0012084)1.92735810
86Abnormality of monocarboxylic acid metabolism (HP:0010996)1.92149311
87Bladder diverticulum (HP:0000015)1.92108783
88Nemaline bodies (HP:0003798)1.91486690
89Spondylolisthesis (HP:0003302)1.89264851
90Hypoplasia of the iris (HP:0007676)1.88695729
91Hypobetalipoproteinemia (HP:0003563)1.88633911
92Mitral valve prolapse (HP:0001634)1.88485414
93Abnormality of dentin (HP:0010299)1.88466959
94Turricephaly (HP:0000262)1.88011304
95Wide anterior fontanel (HP:0000260)1.87087246
96Calcaneovalgus deformity (HP:0001848)1.87009975
97Overgrowth (HP:0001548)1.86865022
98Skin nodule (HP:0200036)1.84880319
99Aortic valve stenosis (HP:0001650)1.84790205
100Mitral stenosis (HP:0001718)1.84133043
101Pulmonic stenosis (HP:0001642)1.83073914
102Ketoacidosis (HP:0001993)1.82303445
103Elbow flexion contracture (HP:0002987)1.80037424
104Rhabdomyolysis (HP:0003201)1.77636730
105Atrioventricular block (HP:0001678)1.76480990
106Abnormality of the acetabulum (HP:0003170)1.76427574
107Deformed tarsal bones (HP:0008119)1.75828125
108Blue sclerae (HP:0000592)1.75750797
109Atrophic scars (HP:0001075)1.75625607
110Spinal cord lesions (HP:0100561)1.75417792
111Syringomyelia (HP:0003396)1.75417792
112Bronchomalacia (HP:0002780)1.75256569
113Abnormality of fatty-acid metabolism (HP:0004359)1.74988782
114Tarsal synostosis (HP:0008368)1.74816344
115Aneurysm (HP:0002617)1.74809376
116Abnormal delivery (HP:0001787)1.74781979
117Vertebral compression fractures (HP:0002953)1.74711151
118Primary atrial arrhythmia (HP:0001692)1.73737635
119Lymphangioma (HP:0100764)1.73494386
120Disproportionate tall stature (HP:0001519)1.73406707
121Difficulty climbing stairs (HP:0003551)1.73197936
122Mildly elevated creatine phosphokinase (HP:0008180)1.72741452
123Arnold-Chiari malformation (HP:0002308)1.72442500
124Preaxial foot polydactyly (HP:0001841)1.71252420
125Cardiovascular calcification (HP:0011915)1.71119333
126Dilated cardiomyopathy (HP:0001644)1.70863127
127Abnormality of the Achilles tendon (HP:0005109)1.69717018
128Neurofibrillary tangles (HP:0002185)1.69643753
129Deviation of the hallux (HP:0010051)1.68342488
130Inguinal hernia (HP:0000023)1.68135326
131Limb-girdle muscle weakness (HP:0003325)1.67865181
132Supraventricular arrhythmia (HP:0005115)1.67028489
133Muscle stiffness (HP:0003552)1.66549396
134Knee flexion contracture (HP:0006380)1.66531939
135Pulmonary artery stenosis (HP:0004415)1.65987181
136Broad ribs (HP:0000885)1.64944365
137Protruding ear (HP:0000411)1.64646167
138Wormian bones (HP:0002645)1.64309803
139Myotonia (HP:0002486)1.64109418
140Delayed cranial suture closure (HP:0000270)1.63993544
141Follicular hyperkeratosis (HP:0007502)1.63760919
142Short nail (HP:0001799)1.63005626
143Focal segmental glomerulosclerosis (HP:0000097)1.62551112
144Neonatal short-limb short stature (HP:0008921)1.62112284
145Broad phalanx (HP:0006009)1.61127753
146Mesangial abnormality (HP:0001966)1.60683402
147Hyperextensible skin (HP:0000974)1.60655190
148Hypoventilation (HP:0002791)1.59556150
149Absent frontal sinuses (HP:0002688)1.59086974
150Hip contracture (HP:0003273)1.58880636
151Flat cornea (HP:0007720)1.58479197
152Bell-shaped thorax (HP:0001591)1.57841069
153Abnormality of the calcaneus (HP:0008364)1.57736484
154Rhizomelia (HP:0008905)1.56064447
155Delayed gross motor development (HP:0002194)1.56056334
156Abnormality of the umbilical cord (HP:0010881)1.54356372
157Hallux valgus (HP:0001822)1.53049547
158Vertebral arch anomaly (HP:0008438)1.52563643

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN3.32653980
2LATS12.86503744
3TRIB32.74713643
4LATS22.47871084
5TIE12.47574907
6STK392.25999254
7OBSCN2.22221204
8MET2.15389225
9LIMK12.13455837
10PDGFRA2.12335340
11BCKDK2.10860279
12DDR22.05538971
13SIK12.00174725
14PHKG11.97523247
15PHKG21.97523247
16DMPK1.95838927
17STK38L1.88822314
18PKN21.72023060
19PIK3CA1.70150493
20MYLK1.69902934
21PAK31.65643825
22EPHB21.63765850
23PBK1.59084360
24PDK41.54906112
25PDK31.54906112
26FER1.54418656
27LMTK21.51115145
28WNK41.50916353
29ERBB41.49966618
30EPHB11.43078056
31PTK2B1.41665043
32FGFR21.41092822
33PDK21.33918970
34TTK1.27326994
35TSSK61.27237046
36PAK21.24953564
37PTK21.23892395
38KDR1.21177028
39AKT31.20299912
40PRKD31.17527756
41NTRK11.16055883
42ROCK11.15653636
43BRSK21.13866900
44BMX1.13290461
45FGFR11.12525666
46RIPK11.08880715
47PTK61.05930519
48PIK3CG1.03538075
49FLT31.00884516
50MKNK20.97990159
51PRKD10.96705598
52PLK30.96628034
53WNK10.95897387
54ROCK20.93621715
55EPHA20.93333434
56CAMK1D0.92910741
57ERN10.89697273
58WEE10.89496912
59CAMK1G0.88742895
60MKNK10.88264109
61EIF2AK30.84689133
62PAK60.84004352
63ILK0.83841633
64NEK10.82278494
65TYRO30.80720574
66TRPM70.79424761
67PKN10.77748357
68PLK20.77621170
69MAP2K10.76241796
70MELK0.75526633
71TAF10.74110629
72MTOR0.73599861
73CAMK2G0.73378729
74NEK90.73372326
75OXSR10.73127957
76PDGFRB0.73119955
77PLK40.72881952
78CDC42BPA0.71255388
79RET0.69798290
80FGFR40.69729539
81CAMK2D0.69437351
82STK30.68381277
83PRKAA20.68377322
84TESK10.68340331
85BCR0.68229096
86DAPK30.65460035
87KSR20.65137106
88TGFBR20.62070893
89GSK3A0.60700632
90EEF2K0.60170879
91MAPK120.59667808
92TGFBR10.59115305
93ERBB20.57575774
94CASK0.57247471
95NEK20.56770966
96MAP3K100.55969001
97CDC70.55497238
98STK380.55389908
99BRSK10.54295776
100EPHA30.54042709
101INSRR0.52903747
102MOS0.52701919
103LRRK20.52131406
104ICK0.51667828
105ERBB30.51132740
106SGK2230.50315191
107SGK4940.50315191
108MAP3K70.50194474
109PRKCE0.48631699
110STK240.48078760
111PRKAA10.47725564
112CAMK2A0.47417725
113PLK10.47079872
114MAP3K120.46544071
115BUB10.43539258
116PRKG20.41345115
117AKT20.41054682
118MAP3K130.40887020
119ABL20.40672015
120PRKACB0.39931591
121PNCK0.39413877
122AURKB0.39404032
123INSR0.39171839
124PDPK10.38135327
125CDK80.37941443
126TESK20.37760088
127PINK10.37215338
128MARK10.36426201
129PRKCH0.35990418
130MAPK70.35805200
131CDK60.35524412
132CSNK1G10.35399400
133CAMK2B0.34046095
134PAK40.33690015
135NEK60.33593974
136EIF2AK20.32516174
137ADRBK10.31307794
138PAK10.31146059
139MUSK0.30952348

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009104.19488811
2Primary bile acid biosynthesis_Homo sapiens_hsa001202.63757370
3Fatty acid degradation_Homo sapiens_hsa000712.56384559
4Propanoate metabolism_Homo sapiens_hsa006402.56307238
5Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.49534445
6Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.48382218
7Fatty acid metabolism_Homo sapiens_hsa012122.30674425
8Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.29777147
9Arginine biosynthesis_Homo sapiens_hsa002202.21397651
10Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.19244412
112-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.19155285
12Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.04573501
13Butanoate metabolism_Homo sapiens_hsa006502.01294507
14Tryptophan metabolism_Homo sapiens_hsa003801.97673928
15PPAR signaling pathway_Homo sapiens_hsa033201.91283785
16Fatty acid elongation_Homo sapiens_hsa000621.89248248
17Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.83998015
18Complement and coagulation cascades_Homo sapiens_hsa046101.74713679
19Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.73814453
20Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.71522725
21Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.61248845
22Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.58195089
23ECM-receptor interaction_Homo sapiens_hsa045121.53226305
24Dilated cardiomyopathy_Homo sapiens_hsa054141.47296094
25Pyruvate metabolism_Homo sapiens_hsa006201.46126184
26Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.45677651
27Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.43103752
28Carbon metabolism_Homo sapiens_hsa012001.43039444
29Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.42083177
30Bile secretion_Homo sapiens_hsa049761.38118769
31Fatty acid biosynthesis_Homo sapiens_hsa000611.35865668
32Peroxisome_Homo sapiens_hsa041461.35503990
33Arginine and proline metabolism_Homo sapiens_hsa003301.35214255
34Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.34116408
35Small cell lung cancer_Homo sapiens_hsa052221.32780761
36Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.29317811
37Steroid biosynthesis_Homo sapiens_hsa001001.26849680
38Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.23653333
39beta-Alanine metabolism_Homo sapiens_hsa004101.23199716
40Sulfur metabolism_Homo sapiens_hsa009201.22455141
41Wnt signaling pathway_Homo sapiens_hsa043101.21959343
42Biosynthesis of amino acids_Homo sapiens_hsa012301.16109049
43Histidine metabolism_Homo sapiens_hsa003401.15799870
44Tyrosine metabolism_Homo sapiens_hsa003501.12222449
45Melanoma_Homo sapiens_hsa052181.11374190
46Focal adhesion_Homo sapiens_hsa045101.10792708
47Chemical carcinogenesis_Homo sapiens_hsa052041.10552001
48Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.10242345
49Phenylalanine metabolism_Homo sapiens_hsa003601.06563657
50AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.04713847
51Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.02446408
52Starch and sucrose metabolism_Homo sapiens_hsa005001.00285274
53Steroid hormone biosynthesis_Homo sapiens_hsa001401.00216984
54Pathways in cancer_Homo sapiens_hsa052000.98631676
55Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.96977994
56Pentose and glucuronate interconversions_Homo sapiens_hsa000400.90735106
57Tight junction_Homo sapiens_hsa045300.89923099
58Adherens junction_Homo sapiens_hsa045200.87497587
59Cell cycle_Homo sapiens_hsa041100.87116091
60Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.84162923
61Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.82874170
62Retinol metabolism_Homo sapiens_hsa008300.82552189
63Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.81022460
64Cardiac muscle contraction_Homo sapiens_hsa042600.80851844
65Hippo signaling pathway_Homo sapiens_hsa043900.78441264
66Vitamin B6 metabolism_Homo sapiens_hsa007500.77464787
67p53 signaling pathway_Homo sapiens_hsa041150.74995810
68Lysine degradation_Homo sapiens_hsa003100.73108125
69Thyroid cancer_Homo sapiens_hsa052160.73084352
70Caffeine metabolism_Homo sapiens_hsa002320.72510653
71Selenocompound metabolism_Homo sapiens_hsa004500.72323460
72Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.71098317
73TGF-beta signaling pathway_Homo sapiens_hsa043500.70266918
74Protein digestion and absorption_Homo sapiens_hsa049740.70207767
75Cysteine and methionine metabolism_Homo sapiens_hsa002700.69846011
76Prostate cancer_Homo sapiens_hsa052150.69162385
77Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.66493895
78Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.66430460
79Basal cell carcinoma_Homo sapiens_hsa052170.64501466
80Circadian rhythm_Homo sapiens_hsa047100.64183312
81Proteoglycans in cancer_Homo sapiens_hsa052050.63736543
82Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.61895128
83One carbon pool by folate_Homo sapiens_hsa006700.61230287
84Fat digestion and absorption_Homo sapiens_hsa049750.61127567
85Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.58935188
86Hedgehog signaling pathway_Homo sapiens_hsa043400.58204446
87Thyroid hormone signaling pathway_Homo sapiens_hsa049190.58082869
88Glycerolipid metabolism_Homo sapiens_hsa005610.57917838
89Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.57737947
90Thyroid hormone synthesis_Homo sapiens_hsa049180.57532148
91Amoebiasis_Homo sapiens_hsa051460.56857213
92Prion diseases_Homo sapiens_hsa050200.54937976
93Glutathione metabolism_Homo sapiens_hsa004800.52999204
94Insulin resistance_Homo sapiens_hsa049310.49675074
95Adipocytokine signaling pathway_Homo sapiens_hsa049200.49603238
96AMPK signaling pathway_Homo sapiens_hsa041520.49581712
97Ovarian steroidogenesis_Homo sapiens_hsa049130.49335843
98Bladder cancer_Homo sapiens_hsa052190.48286890
99Glucagon signaling pathway_Homo sapiens_hsa049220.47480838
100Axon guidance_Homo sapiens_hsa043600.47041766
101Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.46119726
102Glioma_Homo sapiens_hsa052140.45851786
103Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.45130329
104Longevity regulating pathway - mammal_Homo sapiens_hsa042110.44817390
105Dorso-ventral axis formation_Homo sapiens_hsa043200.44718035
106Vascular smooth muscle contraction_Homo sapiens_hsa042700.43938469
107Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.43453834
108Chronic myeloid leukemia_Homo sapiens_hsa052200.42390417
109Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.41922974
110Vitamin digestion and absorption_Homo sapiens_hsa049770.41676738
111Non-homologous end-joining_Homo sapiens_hsa034500.41268894
112Oocyte meiosis_Homo sapiens_hsa041140.41131621
113Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.40681189
114PI3K-Akt signaling pathway_Homo sapiens_hsa041510.40460989
115RNA transport_Homo sapiens_hsa030130.39513858
116Ras signaling pathway_Homo sapiens_hsa040140.38712338
117Phospholipase D signaling pathway_Homo sapiens_hsa040720.38466467
118Leukocyte transendothelial migration_Homo sapiens_hsa046700.37870069
119Central carbon metabolism in cancer_Homo sapiens_hsa052300.36568115
120Renal cell carcinoma_Homo sapiens_hsa052110.34527698
121Regulation of actin cytoskeleton_Homo sapiens_hsa048100.33596368
122Folate biosynthesis_Homo sapiens_hsa007900.33126496
123ABC transporters_Homo sapiens_hsa020100.30061816
124cGMP-PKG signaling pathway_Homo sapiens_hsa040220.28814186
125Drug metabolism - other enzymes_Homo sapiens_hsa009830.27152729
126Melanogenesis_Homo sapiens_hsa049160.25987600
127Rap1 signaling pathway_Homo sapiens_hsa040150.25601884
128Insulin signaling pathway_Homo sapiens_hsa049100.25598384
129MicroRNAs in cancer_Homo sapiens_hsa052060.25539480
130Gap junction_Homo sapiens_hsa045400.24753974
131alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.24301383
132Metabolic pathways_Homo sapiens_hsa011000.23811324

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »