FEZF2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.34388402
2cell proliferation in forebrain (GO:0021846)5.81214826
3somite development (GO:0061053)5.50033160
4synaptic vesicle maturation (GO:0016188)5.30926892
5synaptic vesicle exocytosis (GO:0016079)5.27543407
6vocalization behavior (GO:0071625)5.18929538
7proline transport (GO:0015824)5.13784871
8ionotropic glutamate receptor signaling pathway (GO:0035235)5.12661637
9glutamate secretion (GO:0014047)4.86742865
10regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.85092292
11regulation of short-term neuronal synaptic plasticity (GO:0048172)4.76941096
12positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.73387903
13protein localization to synapse (GO:0035418)4.72949222
14glutamate receptor signaling pathway (GO:0007215)4.65012337
15tongue development (GO:0043586)4.63973634
16locomotory exploration behavior (GO:0035641)4.63206734
17regulation of glutamate receptor signaling pathway (GO:1900449)4.56402356
18positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.45451342
19layer formation in cerebral cortex (GO:0021819)4.42391811
20synaptic transmission, glutamatergic (GO:0035249)4.38444376
21neuron fate determination (GO:0048664)4.30905021
22positive regulation of growth hormone secretion (GO:0060124)4.26166570
23maturation of SSU-rRNA (GO:0030490)4.25712864
24epithelial cilium movement (GO:0003351)4.25161862
25synaptic vesicle docking involved in exocytosis (GO:0016081)4.22641918
26ribosomal small subunit biogenesis (GO:0042274)4.19987119
27regulation of growth hormone secretion (GO:0060123)4.19584524
28behavioral response to nicotine (GO:0035095)4.16115657
29neuron cell-cell adhesion (GO:0007158)4.15361150
30negative regulation of astrocyte differentiation (GO:0048712)4.14585015
31ribosomal small subunit assembly (GO:0000028)4.12010971
32regulation of dendritic cell antigen processing and presentation (GO:0002604)4.10628024
33regulation of synaptic vesicle exocytosis (GO:2000300)4.08862078
34* neuron recognition (GO:0008038)4.06938824
35viral transcription (GO:0019083)4.04881201
36olfactory bulb development (GO:0021772)4.04078630
37neuronal action potential propagation (GO:0019227)4.03382276
38neurotransmitter-gated ion channel clustering (GO:0072578)3.98903814
39exploration behavior (GO:0035640)3.97986361
40pyrimidine nucleobase catabolic process (GO:0006208)3.89314668
41positive regulation of neuroblast proliferation (GO:0002052)3.87939527
42neuron-neuron synaptic transmission (GO:0007270)3.87829244
43thalamus development (GO:0021794)3.84432249
44neurotransmitter catabolic process (GO:0042135)3.82873078
45regulation of long-term neuronal synaptic plasticity (GO:0048169)3.82114520
46translational termination (GO:0006415)3.81702953
47neuronal stem cell maintenance (GO:0097150)3.79182205
48regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.78532133
49oxygen transport (GO:0015671)3.77150298
50growth hormone secretion (GO:0030252)3.70668880
51regulation of synaptic vesicle transport (GO:1902803)3.67527763
52regulation of excitatory postsynaptic membrane potential (GO:0060079)3.67504195
53regulation of neuronal synaptic plasticity (GO:0048168)3.65931106
54central nervous system myelination (GO:0022010)3.64712632
55axon ensheathment in central nervous system (GO:0032291)3.64712632
56cilium movement (GO:0003341)3.63446182
57regulation of neuroblast proliferation (GO:1902692)3.60642879
58synaptic vesicle endocytosis (GO:0048488)3.60462542
59positive regulation of synapse maturation (GO:0090129)3.59696253
60regulation of dendritic spine morphogenesis (GO:0061001)3.53906682
61long-term synaptic potentiation (GO:0060291)3.53480538
62axonemal dynein complex assembly (GO:0070286)3.52974821
63regulation of postsynaptic membrane potential (GO:0060078)3.50146917
64intraciliary transport (GO:0042073)3.50020281
65neurotransmitter secretion (GO:0007269)3.49317896
66response to histamine (GO:0034776)3.48322947
67appendage development (GO:0048736)3.46621381
68limb development (GO:0060173)3.46621381
69dendritic spine morphogenesis (GO:0060997)3.44713678
70* axonal fasciculation (GO:0007413)3.44266259
71telencephalon development (GO:0021537)3.43824097
72dorsal/ventral pattern formation (GO:0009953)3.40736417
73negative regulation of peptidyl-threonine phosphorylation (GO:0010801)3.40067816
74axon extension involved in axon guidance (GO:0048846)3.39002315
75neuron projection extension involved in neuron projection guidance (GO:1902284)3.39002315
76G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.36040314
77postsynaptic membrane organization (GO:0001941)3.35767613
78presynaptic membrane assembly (GO:0097105)3.34152718
79cerebellar granule cell differentiation (GO:0021707)3.31985594
80regulation of synaptic plasticity (GO:0048167)3.31754226
81regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.30978518
82auditory behavior (GO:0031223)3.29833217
83cellular potassium ion homeostasis (GO:0030007)3.28441087
84positive regulation of dendritic spine morphogenesis (GO:0061003)3.26795788
85gamma-aminobutyric acid signaling pathway (GO:0007214)3.25187300
86response to auditory stimulus (GO:0010996)3.24569273
87long-term memory (GO:0007616)3.23030289
88regulation of synapse structural plasticity (GO:0051823)3.20634049
89positive regulation of neurotransmitter secretion (GO:0001956)3.14980230
90sodium ion export (GO:0071436)3.14923931
91regulation of vesicle fusion (GO:0031338)3.14140133
92negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.12497394
93behavioral fear response (GO:0001662)3.10935574
94behavioral defense response (GO:0002209)3.10935574
95arginine catabolic process (GO:0006527)3.10932037
96positive regulation of filopodium assembly (GO:0051491)3.06855902
97spinal cord association neuron differentiation (GO:0021527)3.06694564
98regulation of T-helper 1 cell differentiation (GO:0045625)3.05766573
99positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.04812698
100nucleobase catabolic process (GO:0046113)3.04449513
101mechanosensory behavior (GO:0007638)3.03914747
102dendrite morphogenesis (GO:0048813)3.03142521
103camera-type eye morphogenesis (GO:0048593)3.02049605
104G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.01997625
105regulation of dendritic spine development (GO:0060998)3.01085789
106segment specification (GO:0007379)3.00817084
107positive regulation of oligodendrocyte differentiation (GO:0048714)3.00654138
108presynaptic membrane organization (GO:0097090)3.00501702
109central nervous system projection neuron axonogenesis (GO:0021952)3.00364818
110regulation of non-canonical Wnt signaling pathway (GO:2000050)2.99585417
111cellular protein complex disassembly (GO:0043624)2.99451393
112innervation (GO:0060384)2.99159943
113positive regulation of membrane potential (GO:0045838)2.98738244
114neurotransmitter transport (GO:0006836)2.98489575
115translational elongation (GO:0006414)2.96894514
116positive regulation of neural precursor cell proliferation (GO:2000179)2.96322485
117dendritic spine organization (GO:0097061)2.96177840
118auditory receptor cell differentiation (GO:0042491)2.95337719
119left/right pattern formation (GO:0060972)2.95185428
120retinal ganglion cell axon guidance (GO:0031290)2.94409336
121positive regulation of dendritic spine development (GO:0060999)2.93232829
122regulation of synaptic transmission, glutamatergic (GO:0051966)2.92866111
123spinal cord development (GO:0021510)2.91484811
124transmission of nerve impulse (GO:0019226)2.90919972
125gamma-aminobutyric acid transport (GO:0015812)2.89739914
126regulation of neurotransmitter levels (GO:0001505)2.87823799
127smoothened signaling pathway (GO:0007224)2.87596477
128nonmotile primary cilium assembly (GO:0035058)2.87316704
129positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.87137741
130fear response (GO:0042596)2.86558806
131cell communication by electrical coupling (GO:0010644)2.86520260
132learning (GO:0007612)2.86269766
133negative regulation of oligodendrocyte differentiation (GO:0048715)2.84968946
134positive regulation of neurological system process (GO:0031646)2.84337100
135negative regulation of synaptic transmission, GABAergic (GO:0032229)2.83895340
136forebrain morphogenesis (GO:0048853)2.82944127
137radial glial cell differentiation (GO:0060019)2.82845279
138forebrain neuron differentiation (GO:0021879)2.82677366
139cell migration in hindbrain (GO:0021535)2.82670267
140positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568)2.82586238
141chemosensory behavior (GO:0007635)2.81811229
142SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.81712234
143positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.81582864
144cotranslational protein targeting to membrane (GO:0006613)2.80773470
145activation of protein kinase A activity (GO:0034199)2.80644880
146determination of left/right symmetry (GO:0007368)2.79614594
147asymmetric protein localization (GO:0008105)2.79493264
148regulation of neurotransmitter secretion (GO:0046928)2.78940596
149synapse assembly (GO:0007416)2.78637607
150membrane depolarization (GO:0051899)2.78520121
151neuromuscular process controlling balance (GO:0050885)2.78006583
152positive regulation of granulocyte chemotaxis (GO:0071624)2.77986279
153regulation of cAMP-dependent protein kinase activity (GO:2000479)2.77704325
154membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.77473532
155dorsal/ventral neural tube patterning (GO:0021904)2.77055046
156protein targeting to ER (GO:0045047)2.76612189
157short-term memory (GO:0007614)2.76026903
158viral life cycle (GO:0019058)2.75523823
159negative regulation of glial cell differentiation (GO:0045686)2.75190340
160regulation of cilium movement (GO:0003352)2.74668306
161protein complex disassembly (GO:0043241)2.73990418
162cerebral cortex radially oriented cell migration (GO:0021799)2.73017064
163cerebral cortex neuron differentiation (GO:0021895)2.72648902
164neuron fate commitment (GO:0048663)2.70948291
165regulation of timing of cell differentiation (GO:0048505)2.70012176
166cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.69550732
167long term synaptic depression (GO:0060292)2.69414808
168adult walking behavior (GO:0007628)2.68284949
169regulation of synapse maturation (GO:0090128)2.67641058
170protein polyglutamylation (GO:0018095)2.67376203
171positive regulation of synaptic transmission (GO:0050806)2.66758582
172cell communication involved in cardiac conduction (GO:0086065)2.66151156
173establishment of protein localization to endoplasmic reticulum (GO:0072599)2.63764725
174ganglion development (GO:0061548)2.61542117
175protein localization to endoplasmic reticulum (GO:0070972)2.60635303
176nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.59447888
177determination of bilateral symmetry (GO:0009855)2.59117234
178regulation of astrocyte differentiation (GO:0048710)2.56338263
179positive regulation of sodium ion transmembrane transport (GO:1902307)2.55623320
180cardiovascular system development (GO:0072358)2.55590306
181activation of MAPKKK activity (GO:0000185)2.55174185
182cAMP-mediated signaling (GO:0019933)2.54988889
183macromolecular complex disassembly (GO:0032984)2.54365474
184specification of symmetry (GO:0009799)2.53165706

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.45394839
2GBX2_23144817_ChIP-Seq_PC3_Human3.45511802
3* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.14216358
4* JARID2_20064375_ChIP-Seq_MESCs_Mouse3.07974901
5* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.85477058
6* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.75369095
7SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.70830153
8* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.66647658
9* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.64217379
10* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.64217379
11* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.56719913
12* EZH2_27304074_Chip-Seq_ESCs_Mouse2.49907565
13RBPJ_22232070_ChIP-Seq_NCS_Mouse2.47097006
14* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.45672780
15* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.44205553
16EED_16625203_ChIP-ChIP_MESCs_Mouse2.43659836
17DROSHA_22980978_ChIP-Seq_HELA_Human2.39690648
18HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.37605761
19REST_21632747_ChIP-Seq_MESCs_Mouse2.30900650
20* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.23607330
21* RNF2_27304074_Chip-Seq_ESCs_Mouse2.19083844
22AR_21572438_ChIP-Seq_LNCaP_Human2.14507680
23* EZH2_27294783_Chip-Seq_ESCs_Mouse2.08085283
24IKZF1_21737484_ChIP-ChIP_HCT116_Human2.01106380
25CTBP2_25329375_ChIP-Seq_LNCAP_Human1.93690398
26CTBP1_25329375_ChIP-Seq_LNCAP_Human1.81748152
27RARB_27405468_Chip-Seq_BRAIN_Mouse1.80888274
28TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.73990925
29NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.73923354
30REST_18959480_ChIP-ChIP_MESCs_Mouse1.71612150
31IRF1_19129219_ChIP-ChIP_H3396_Human1.68782182
32SMAD4_21799915_ChIP-Seq_A2780_Human1.61931359
33POU5F1_16153702_ChIP-ChIP_HESCs_Human1.61528611
34ERG_21242973_ChIP-ChIP_JURKAT_Human1.59108677
35HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.59055795
36GATA1_26923725_Chip-Seq_HPCs_Mouse1.58294486
37SMAD_19615063_ChIP-ChIP_OVARY_Human1.58180481
38TAF15_26573619_Chip-Seq_HEK293_Human1.56356024
39RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.53846099
40VDR_22108803_ChIP-Seq_LS180_Human1.53757123
41PIAS1_25552417_ChIP-Seq_VCAP_Human1.53242869
42ZFP57_27257070_Chip-Seq_ESCs_Mouse1.53204369
43* P300_19829295_ChIP-Seq_ESCs_Human1.52192587
44OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.51653106
45MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.51038549
46TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.49554660
47KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.49512290
48PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.49387947
49PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.47881464
50TP63_19390658_ChIP-ChIP_HaCaT_Human1.45481959
51FUS_26573619_Chip-Seq_HEK293_Human1.44774523
52SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.44213532
53RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.43204520
54ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.39301941
55AR_25329375_ChIP-Seq_VCAP_Human1.38412799
56* CBX2_27304074_Chip-Seq_ESCs_Mouse1.38093985
57SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.36508177
58NR3C1_23031785_ChIP-Seq_PC12_Mouse1.33126487
59IGF1R_20145208_ChIP-Seq_DFB_Human1.32209998
60GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.32133243
61TOP2B_26459242_ChIP-Seq_MCF-7_Human1.31591605
62SMAD3_21741376_ChIP-Seq_EPCs_Human1.30972629
63ZNF274_21170338_ChIP-Seq_K562_Hela1.30755335
64* RING1B_27294783_Chip-Seq_ESCs_Mouse1.30394264
65ARNT_22903824_ChIP-Seq_MCF-7_Human1.28595295
66* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.27324852
67SOX2_21211035_ChIP-Seq_LN229_Gbm1.25250868
68GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.25100949
69TP53_18474530_ChIP-ChIP_U2OS_Human1.24027377
70TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.23499453
71POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.23499453
72TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.22293092
73CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.21585768
74BCAT_22108803_ChIP-Seq_LS180_Human1.21524802
75* RING1B_27294783_Chip-Seq_NPCs_Mouse1.21282093
76CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.20840120
77SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.20515468
78ZNF217_24962896_ChIP-Seq_MCF-7_Human1.19834889
79TP53_16413492_ChIP-PET_HCT116_Human1.19535168
80CDX2_19796622_ChIP-Seq_MESCs_Mouse1.18975830
81AHR_22903824_ChIP-Seq_MCF-7_Human1.16984238
82EWS_26573619_Chip-Seq_HEK293_Human1.16523862
83* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.14852121
84STAT3_23295773_ChIP-Seq_U87_Human1.14824437
85SOX2_18555785_ChIP-Seq_MESCs_Mouse1.14463948
86PRDM14_20953172_ChIP-Seq_ESCs_Human1.14165815
87OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.13605577
88MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.11958124
89CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.11627325
90WT1_25993318_ChIP-Seq_PODOCYTE_Human1.09005924
91* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.08881069
92AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.08662757
93* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.08593740
94TCF4_23295773_ChIP-Seq_U87_Human1.05883616
95AR_19668381_ChIP-Seq_PC3_Human1.05794101
96POU3F2_20337985_ChIP-ChIP_501MEL_Human1.05792748
97P53_22127205_ChIP-Seq_FIBROBLAST_Human1.05244304
98VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.04573526
99* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.03590544
100ISL1_27105846_Chip-Seq_CPCs_Mouse1.03475724
101SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.03356345
102RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.03233080
103YAP1_20516196_ChIP-Seq_MESCs_Mouse1.03179896
104UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.02848684
105NR3C1_21868756_ChIP-Seq_MCF10A_Human1.01956967
106RXR_22108803_ChIP-Seq_LS180_Human1.01221952
107MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.00226082
108TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.99476531
109NANOG_18555785_Chip-Seq_ESCs_Mouse0.99227484
110IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.98175367
111CBP_20019798_ChIP-Seq_JUKART_Human0.98175367
112WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.98123435
113TCF4_18268006_ChIP-ChIP_LS174T_Human0.97993934
114* ER_23166858_ChIP-Seq_MCF-7_Human0.96968979
115SMAD3_21741376_ChIP-Seq_ESCs_Human0.96916910
116SMAD3_21741376_ChIP-Seq_HESCs_Human0.95826681
117SOX2_16153702_ChIP-ChIP_HESCs_Human0.95267324
118TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.95180114
119TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.95003205
120* CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94777795
121WDR5_24793694_ChIP-Seq_LNCAP_Human0.94290183
122CTCF_27219007_Chip-Seq_Bcells_Human0.94234836
123SALL1_21062744_ChIP-ChIP_HESCs_Human0.93982491
124RUNX2_22187159_ChIP-Seq_PCA_Human0.93854809
125TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93385608
126* TP53_20018659_ChIP-ChIP_R1E_Mouse0.93200755
127* RNF2_27304074_Chip-Seq_NSC_Mouse0.91356659
128JUN_21703547_ChIP-Seq_K562_Human0.91118288
129SOX9_26525672_Chip-Seq_HEART_Mouse0.91032873
130* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.90820034
131ETV2_25802403_ChIP-Seq_MESCs_Mouse0.90249624
132* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.90014923
133CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.89349840

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002254_reproductive_system_inflammat7.33448599
2MP0004859_abnormal_synaptic_plasticity5.51639779
3MP0003880_abnormal_central_pattern3.97066455
4MP0001348_abnormal_lacrimal_gland3.66978215
5MP0002876_abnormal_thyroid_physiology3.55646614
6MP0004270_analgesia3.52994231
7MP0009379_abnormal_foot_pigmentation3.45623454
8MP0003635_abnormal_synaptic_transmissio3.32311587
9MP0010030_abnormal_orbit_morphology3.29222116
10MP0000566_synostosis3.14562276
11MP0001346_abnormal_lacrimal_gland3.11174022
12MP0002653_abnormal_ependyma_morphology3.08133436
13MP0003122_maternal_imprinting3.01737424
14MP0005645_abnormal_hypothalamus_physiol2.85546447
15MP0002063_abnormal_learning/memory/cond2.84882752
16MP0009745_abnormal_behavioral_response2.63803091
17MP0002735_abnormal_chemical_nociception2.58983650
18MP0002734_abnormal_mechanical_nocicepti2.56385794
19MP0003879_abnormal_hair_cell2.54370048
20MP0001501_abnormal_sleep_pattern2.53037525
21MP0003123_paternal_imprinting2.42935733
22MP0002064_seizures2.39966323
23MP0001968_abnormal_touch/_nociception2.38836408
24MP0002572_abnormal_emotion/affect_behav2.27656222
25MP0002736_abnormal_nociception_after2.22110661
26MP0001440_abnormal_grooming_behavior2.11539345
27MP0005423_abnormal_somatic_nervous2.08216876
28MP0002733_abnormal_thermal_nociception2.07159674
29MP0005310_abnormal_salivary_gland2.03673620
30MP0003646_muscle_fatigue2.02770636
31MP0004510_myositis2.02540922
32MP0003329_amyloid_beta_deposits2.01387072
33MP0001293_anophthalmia2.00999664
34MP0004858_abnormal_nervous_system1.95030795
35MP0009046_muscle_twitch1.93879944
36MP0001486_abnormal_startle_reflex1.93659366
37* MP0000778_abnormal_nervous_system1.89677069
38MP0002163_abnormal_gland_morphology1.86025733
39MP0002272_abnormal_nervous_system1.85966989
40MP0003121_genomic_imprinting1.85945681
41MP0009053_abnormal_anal_canal1.85328376
42MP0002233_abnormal_nose_morphology1.80184434
43MP0004133_heterotaxia1.77594124
44MP0001970_abnormal_pain_threshold1.72148670
45MP0000685_abnormal_immune_system1.66955117
46MP0001873_stomach_inflammation1.58775555
47MP0008569_lethality_at_weaning1.56480606
48MP0002557_abnormal_social/conspecific_i1.51388118
49MP0003937_abnormal_limbs/digits/tail_de1.45579784
50MP0002067_abnormal_sensory_capabilities1.44967552
51MP0001502_abnormal_circadian_rhythm1.41582784
52MP0009780_abnormal_chondrocyte_physiolo1.41508451
53MP0008877_abnormal_DNA_methylation1.37990310
54MP0002184_abnormal_innervation1.37384718
55MP0003938_abnormal_ear_development1.35763052
56MP0002249_abnormal_larynx_morphology1.34440081
57MP0002909_abnormal_adrenal_gland1.33437178
58MP0005248_abnormal_Harderian_gland1.31435053
59MP0004043_abnormal_pH_regulation1.28219084
60MP0003755_abnormal_palate_morphology1.28013795
61MP0003942_abnormal_urinary_system1.27328600
62MP0000428_abnormal_craniofacial_morphol1.26598498
63MP0003136_yellow_coat_color1.25439594
64MP0002938_white_spotting1.24715876
65MP0001286_abnormal_eye_development1.23565036
66MP0002116_abnormal_craniofacial_bone1.21273574
67MP0001485_abnormal_pinna_reflex1.21000802
68MP0006276_abnormal_autonomic_nervous1.20102957
69MP0004811_abnormal_neuron_physiology1.20087115
70MP0004924_abnormal_behavior1.17705740
71MP0005386_behavior/neurological_phenoty1.17705740
72MP0004885_abnormal_endolymph1.15290422
73* MP0002882_abnormal_neuron_morphology1.13776015
74MP0010234_abnormal_vibrissa_follicle1.12865580
75MP0002102_abnormal_ear_morphology1.12763428
76* MP0002066_abnormal_motor_capabilities/c1.09480448
77MP0005195_abnormal_posterior_eye1.07810496
78MP0000604_amyloidosis1.06824398
79MP0000955_abnormal_spinal_cord1.05075473
80MP0005647_abnormal_sex_gland1.04685177
81MP0001984_abnormal_olfaction1.04378231
82MP0005377_hearing/vestibular/ear_phenot1.02818018
83MP0003878_abnormal_ear_physiology1.02818018
84MP0003075_altered_response_to0.96939514
85MP0000534_abnormal_ureter_morphology0.95305006
86MP0003890_abnormal_embryonic-extraembry0.90922703
87MP0008872_abnormal_physiological_respon0.90428226
88MP0005499_abnormal_olfactory_system0.88278935
89MP0005394_taste/olfaction_phenotype0.88278935
90MP0002638_abnormal_pupillary_reflex0.87515998
91* MP0002152_abnormal_brain_morphology0.86964604
92MP0002837_dystrophic_cardiac_calcinosis0.85348729
93MP0002160_abnormal_reproductive_system0.84457205
94MP0005379_endocrine/exocrine_gland_phen0.83994268
95MP0002138_abnormal_hepatobiliary_system0.81845213
96MP0002092_abnormal_eye_morphology0.81199956
97MP0001529_abnormal_vocalization0.80283200
98MP0005391_vision/eye_phenotype0.80281812
99MP0005646_abnormal_pituitary_gland0.80175766
100MP0003119_abnormal_digestive_system0.79431593
101MP0006072_abnormal_retinal_apoptosis0.79215250
102* MP0002069_abnormal_eating/drinking_beha0.78952262
103MP0003633_abnormal_nervous_system0.78726946
104MP0005535_abnormal_body_temperature0.78525989
105MP0003787_abnormal_imprinting0.77270279
106MP0001963_abnormal_hearing_physiology0.75403924
107MP0002095_abnormal_skin_pigmentation0.75375473
108MP0002697_abnormal_eye_size0.74562400
109MP0008789_abnormal_olfactory_epithelium0.74222783
110MP0003183_abnormal_peptide_metabolism0.72890108
111MP0005623_abnormal_meninges_morphology0.72485471
112MP0006082_CNS_inflammation0.71925775
113MP0002081_perinatal_lethality0.70894724
114MP0008874_decreased_physiological_sensi0.69606144
115MP0003283_abnormal_digestive_organ0.68877222
116MP0002234_abnormal_pharynx_morphology0.68698152
117MP0006292_abnormal_olfactory_placode0.68484530
118MP0002111_abnormal_tail_morphology0.67348441
119MP0003631_nervous_system_phenotype0.67276900
120MP0002109_abnormal_limb_morphology0.66544772
121MP0000026_abnormal_inner_ear0.66083870
122MP0005167_abnormal_blood-brain_barrier0.64632758
123MP0000751_myopathy0.64002362
124MP0000537_abnormal_urethra_morphology0.63643396
125MP0002752_abnormal_somatic_nervous0.63353695
126MP0000631_abnormal_neuroendocrine_gland0.63071957
127MP0001905_abnormal_dopamine_level0.62112393
128MP0004142_abnormal_muscle_tone0.61173612
129MP0004484_altered_response_of0.60595089
130MP0004215_abnormal_myocardial_fiber0.59996800
131MP0000613_abnormal_salivary_gland0.58818065
132MP0000579_abnormal_nail_morphology0.57169891
133MP0003634_abnormal_glial_cell0.56687613
134MP0010678_abnormal_skin_adnexa0.56068881
135MP0003638_abnormal_response/metabolism_0.54786678
136MP0004742_abnormal_vestibular_system0.53532934
137MP0005551_abnormal_eye_electrophysiolog0.52482884
138MP0003045_fibrosis0.52360826
139MP0002229_neurodegeneration0.51752300
140MP0003137_abnormal_impulse_conducting0.46332596
141MP0001177_atelectasis0.45970031
142MP0001664_abnormal_digestion0.44745276
143* MP0003861_abnormal_nervous_system0.44629215
144MP0005187_abnormal_penis_morphology0.44252966
145MP0004085_abnormal_heartbeat0.43812103
146MP0000049_abnormal_middle_ear0.43267859
147MP0000678_abnormal_parathyroid_gland0.42447887

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.86536685
2Myokymia (HP:0002411)5.47058587
3Epileptic encephalopathy (HP:0200134)5.27120867
4Focal seizures (HP:0007359)5.13554302
5Cerebral inclusion bodies (HP:0100314)4.41981812
6Neurofibrillary tangles (HP:0002185)4.33007942
7Chronic mucocutaneous candidiasis (HP:0002728)4.27172353
8Recurrent cutaneous fungal infections (HP:0011370)4.27172353
9Visual hallucinations (HP:0002367)4.20271731
10Supranuclear gaze palsy (HP:0000605)4.04026955
11Hyperventilation (HP:0002883)4.02667883
12Reticulocytopenia (HP:0001896)3.96104401
13Keratoconjunctivitis (HP:0001096)3.94191068
14Atonic seizures (HP:0010819)3.92625971
15Febrile seizures (HP:0002373)3.82582615
16Progressive cerebellar ataxia (HP:0002073)3.70903842
17Abnormality of midbrain morphology (HP:0002418)3.70256829
18Molar tooth sign on MRI (HP:0002419)3.70256829
19Absence seizures (HP:0002121)3.60817914
20Pancreatic fibrosis (HP:0100732)3.59090470
21Aplasia/Hypoplasia of the spleen (HP:0010451)3.51986399
22Septo-optic dysplasia (HP:0100842)3.49805876
23Hepatoblastoma (HP:0002884)3.49622971
24Rib fusion (HP:0000902)3.48780612
25Hypercortisolism (HP:0001578)3.37906842
26Abnormality of calcium-phosphate metabolism (HP:0100530)3.32914929
27Excessive salivation (HP:0003781)3.26094703
28Drooling (HP:0002307)3.26094703
29Diplopia (HP:0000651)3.24336415
30Abnormality of binocular vision (HP:0011514)3.24336415
31Generalized tonic-clonic seizures (HP:0002069)3.22893449
32Dialeptic seizures (HP:0011146)3.22505723
33Broad-based gait (HP:0002136)3.21035736
34Pancreatic cysts (HP:0001737)3.18496038
35Asplenia (HP:0001746)3.14599473
36Megalencephaly (HP:0001355)3.12662910
37Type I diabetes mellitus (HP:0100651)3.03168959
38Nephronophthisis (HP:0000090)2.95983358
39Poor eye contact (HP:0000817)2.91344686
40Adrenal hypoplasia (HP:0000835)2.88315593
41Oligodactyly (HP:0012165)2.87656296
42Impaired vibration sensation in the lower limbs (HP:0002166)2.86605861
43Hemiparesis (HP:0001269)2.86575845
44Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.84706459
45Amblyopia (HP:0000646)2.84678882
46Epileptiform EEG discharges (HP:0011182)2.82400098
47Facial hemangioma (HP:0000329)2.81959269
48Oligodactyly (hands) (HP:0001180)2.80030233
49Medial flaring of the eyebrow (HP:0010747)2.74405932
50Genetic anticipation (HP:0003743)2.73466182
51Abnormality of cells of the erythroid lineage (HP:0012130)2.72162103
52Abnormal social behavior (HP:0012433)2.71695732
53Impaired social interactions (HP:0000735)2.71695732
54Neoplasm of the adrenal cortex (HP:0100641)2.67467794
55Renal dysplasia (HP:0000110)2.65948239
56Abnormality of the 4th metacarpal (HP:0010012)2.62511745
57EEG with generalized epileptiform discharges (HP:0011198)2.62205274
58Abnormal respiratory epithelium morphology (HP:0012253)2.61325161
59Abnormal respiratory motile cilium morphology (HP:0005938)2.61325161
60True hermaphroditism (HP:0010459)2.60327489
61Abnormality of salivation (HP:0100755)2.59609512
62Median cleft lip (HP:0000161)2.58839933
63Absent speech (HP:0001344)2.58662415
64Anophthalmia (HP:0000528)2.57247972
65Postaxial foot polydactyly (HP:0001830)2.56436689
66Supernumerary spleens (HP:0009799)2.53789100
67Abnormal number of incisors (HP:0011064)2.52695099
68Depression (HP:0000716)2.51463413
69Diastasis recti (HP:0001540)2.50112448
70Cystic liver disease (HP:0006706)2.48964734
71Ectopic kidney (HP:0000086)2.48535311
72Hypsarrhythmia (HP:0002521)2.46544659
73Short 4th metacarpal (HP:0010044)2.45196888
74Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.45196888
75Abnormality of the renal medulla (HP:0100957)2.45185806
76Aplasia/Hypoplasia of the sacrum (HP:0008517)2.44215411
77Anxiety (HP:0000739)2.43571943
78Tubular atrophy (HP:0000092)2.42680995
79Dysmetria (HP:0001310)2.38152507
80Action tremor (HP:0002345)2.37995385
81Optic nerve hypoplasia (HP:0000609)2.36486107
82Abnormality of the gastric mucosa (HP:0004295)2.35327095
83Truncus arteriosus (HP:0001660)2.34748408
84Pendular nystagmus (HP:0012043)2.33066873
85Absent thumb (HP:0009777)2.32985447
86Absent/shortened dynein arms (HP:0200106)2.31210813
87Dynein arm defect of respiratory motile cilia (HP:0012255)2.31210813
88Congenital primary aphakia (HP:0007707)2.30664778
89Gait imbalance (HP:0002141)2.30138840
90Insidious onset (HP:0003587)2.29731633
91Termporal pattern (HP:0011008)2.29731633
92Confusion (HP:0001289)2.29416816
93Fibular hypoplasia (HP:0003038)2.27808748
94Gaze-evoked nystagmus (HP:0000640)2.27490007
9511 pairs of ribs (HP:0000878)2.27123036
96Anencephaly (HP:0002323)2.24820747
97Truncal ataxia (HP:0002078)2.23885328
98Postaxial hand polydactyly (HP:0001162)2.23334315
99Colon cancer (HP:0003003)2.23104519
100Maternal diabetes (HP:0009800)2.22309826
101Broad thumb (HP:0011304)2.20751385
102Abnormality of the aortic arch (HP:0012303)2.20397619
103Obstructive sleep apnea (HP:0002870)2.20381037
104Mutism (HP:0002300)2.19668334
105Ankyloglossia (HP:0010296)2.18893906
106Sclerocornea (HP:0000647)2.18380214
107Annular pancreas (HP:0001734)2.17271622
108Holoprosencephaly (HP:0001360)2.16062310
109Hypoparathyroidism (HP:0000829)2.15035519
110Polydipsia (HP:0001959)2.13063690
111Abnormal drinking behavior (HP:0030082)2.13063690
112Stereotypic behavior (HP:0000733)2.11921714
113Abnormal respiratory motile cilium physiology (HP:0012261)2.11449494
114Delusions (HP:0000746)2.10212533
115Postural instability (HP:0002172)2.10200700
116Deep palmar crease (HP:0006191)2.09661529
117Congenital hepatic fibrosis (HP:0002612)2.09525294
118Inappropriate behavior (HP:0000719)2.09060213
119Dysdiadochokinesis (HP:0002075)2.08908105
120Absent septum pellucidum (HP:0001331)2.08764970
121Nephrogenic diabetes insipidus (HP:0009806)2.08323339
122Partial duplication of thumb phalanx (HP:0009944)2.07718456
123Onycholysis (HP:0001806)2.07716376
124Poor coordination (HP:0002370)2.07496136
125Urinary bladder sphincter dysfunction (HP:0002839)2.06861956
126High anterior hairline (HP:0009890)2.06842677
127Papilledema (HP:0001085)2.06504218
128Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.05782075
129Abnormal eating behavior (HP:0100738)2.05703447
130Cerebellar dysplasia (HP:0007033)2.05295444
131Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.04300887
132Bifid tongue (HP:0010297)2.04034107
133Preaxial hand polydactyly (HP:0001177)2.03476036
134Impaired smooth pursuit (HP:0007772)2.01982097
135Broad phalanges of the hand (HP:0009768)2.01158568
136Synostosis of carpal bones (HP:0005048)2.01062627
137Abnormal number of erythroid precursors (HP:0012131)1.99043241
138Type II lissencephaly (HP:0007260)1.98617958
139Abnormality of the metopic suture (HP:0005556)1.97681699
140Hypoplasia of dental enamel (HP:0006297)1.96934141
141Hypoplasia of the ulna (HP:0003022)1.96582999
142Vitreoretinal degeneration (HP:0000655)1.96515975
143Abnormality of the corticospinal tract (HP:0002492)1.95345861
144Right ventricular cardiomyopathy (HP:0011663)1.95311420
145Abnormality of the diencephalon (HP:0010662)1.95198834
146Growth hormone deficiency (HP:0000824)1.94904780
147Enlarged kidneys (HP:0000105)1.94363996
148Aplasia/Hypoplasia of the tongue (HP:0010295)1.93978887
149Ankle clonus (HP:0011448)1.93035035
150Abnormal ciliary motility (HP:0012262)1.92756805
151Protruding tongue (HP:0010808)1.92533134
152Broad finger (HP:0001500)1.92387848
153Abnormality of cochlea (HP:0000375)1.91556260
154Abnormality of the nasal septum (HP:0000419)1.90643208
155Polyphagia (HP:0002591)1.90316645
156Upper limb muscle weakness (HP:0003484)1.90143964
157Submucous cleft hard palate (HP:0000176)1.88686977
158Status epilepticus (HP:0002133)1.88120540
159Plantar hyperkeratosis (HP:0007556)1.87124834
160Urinary urgency (HP:0000012)1.85927863
161Narrow forehead (HP:0000341)1.85085007
162Impaired vibratory sensation (HP:0002495)1.84730816
163Bradykinesia (HP:0002067)1.84023929
164Broad phalanx (HP:0006009)1.83709694
165Dandy-Walker malformation (HP:0001305)1.83220459
166Chronic hepatic failure (HP:0100626)1.82855093
167Esophageal atresia (HP:0002032)1.82589155
168Micropenis (HP:0000054)1.82482931
169Capillary hemangiomas (HP:0005306)1.81529421
170Cholelithiasis (HP:0001081)1.80616510
171Anosmia (HP:0000458)1.80211489
172Lower limb muscle weakness (HP:0007340)1.79545826
173Abnormality of the labia minora (HP:0012880)1.79298334
174Abnormality of DNA repair (HP:0003254)1.78567314
175Lower limb amyotrophy (HP:0007210)1.78210841
176Abnormality of the renal cortex (HP:0011035)1.78105050
177Vaginal atresia (HP:0000148)1.77874049
178Bronchomalacia (HP:0002780)1.76568850
179Inability to walk (HP:0002540)1.74296068
180Aplasia involving bones of the extremities (HP:0009825)1.74049904
181Aplasia involving bones of the upper limbs (HP:0009823)1.74049904
182Aplasia of the phalanges of the hand (HP:0009802)1.74049904
183Fragile nails (HP:0001808)1.73553459
184Double outlet right ventricle (HP:0001719)1.73515405
185Congenital malformation of the right heart (HP:0011723)1.73515405
186Progressive inability to walk (HP:0002505)1.73466131
187Spastic gait (HP:0002064)1.73328743
188Scanning speech (HP:0002168)1.72497711
189Generalized myoclonic seizures (HP:0002123)1.72374354
190Amelogenesis imperfecta (HP:0000705)1.71459611

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.71708732
2NTRK33.89535332
3MARK13.48054618
4MAP3K93.19180004
5NME12.73592539
6CASK2.70318634
7RIPK42.68924112
8DAPK22.66885801
9WNK42.65412348
10MAP3K42.54226326
11PINK12.35765301
12MAP2K72.23364549
13WNK32.19927014
14MINK12.14331920
15PAK62.05049668
16NTRK22.03771565
17PLK21.97519484
18MAP3K131.95019135
19KSR11.94291314
20MARK21.93110242
21STK391.86953950
22GRK51.85324427
23STK241.85239435
24BMPR21.82433593
25NTRK11.80409019
26PNCK1.80340752
27KSR21.78012004
28CAMK1G1.77786159
29MAP3K141.69656860
30MAP3K121.69372643
31CDK191.64370792
32CAMK1D1.63179408
33CDC71.61679556
34TNIK1.48347158
35MAPK131.47300026
36CAMKK21.37499274
37PIK3CA1.36064382
38PRKD31.36024447
39CDK51.35593368
40DAPK11.34311031
41DYRK1A1.34273437
42MAP2K41.34205569
43CAMK41.33770146
44AKT31.31915540
45BRAF1.31245512
46MKNK21.27919381
47SIK21.17913966
48ZAK1.17580894
49PRKCG1.14467217
50SGK21.14156399
51PHKG21.10945983
52PHKG11.10945983
53FRK1.10804701
54PTK2B1.10004966
55MAP4K21.09095662
56TIE11.06738127
57EPHA31.05737769
58WNK11.04402463
59STK161.04379223
60BRSK11.03415868
61NUAK11.03076947
62ERBB31.02082383
63CAMK2A1.01381309
64LATS20.99946706
65RPS6KA60.99767064
66RAF10.94757865
67MAP3K70.93362776
68FGR0.93174623
69CAMKK10.93023211
70TYRO30.92059556
71MAP3K110.91789393
72ARAF0.89462334
73STK110.89349097
74RPS6KC10.88682391
75RPS6KL10.88682391
76FER0.88384448
77GRK10.87184636
78AURKA0.86639435
79BCKDK0.86099960
80PRPF4B0.85228194
81SGK30.85034963
82CAMK2B0.84929253
83PLK40.83978165
84CDK180.81283408
85BRSK20.79697674
86LRRK20.78789494
87CDK150.77978722
88PAK30.75700820
89CDK140.73840240
90CDC42BPA0.73020629
91LMTK20.71808291
92UHMK10.70261054
93PRKCH0.68898699
94OXSR10.68502357
95SGK10.67139314
96BMPR1B0.66897393
97TRIM280.66838362
98FGFR20.66455024
99PRKCE0.66011211
100CDK11A0.65609159
101BCR0.64415145
102MAP3K20.61683016
103CDK30.61443805
104FES0.60977517
105RET0.60230261
106CHEK20.59921045
107DYRK20.59538714
108CAMK10.59135958
109DYRK30.58041040
110NEK20.57432910
111WEE10.55645964
112TLK10.55600346
113PRKCZ0.55559319
114ROCK20.55164150
115MAPK150.54809565
116PLK10.53866063
117GRK60.53705334
118MAP3K60.53635236
119ADRBK20.53508826
120MAP2K10.49352898
121TAOK10.47954020
122PRKACA0.47159499
123AURKB0.46455700
124EPHB20.46176678
125SCYL20.44314543
126DMPK0.44217364
127ROCK10.43122822
128PKN10.43071688
129AKT10.40237415
130CAMK2G0.39678842
131RPS6KA20.39558539
132DAPK30.37356591
133CSNK1E0.37352686
134ERBB20.36999926
135PRKCQ0.36450812
136DDR20.35432182
137MAP3K10.35114350
138SYK0.35093178
139SGK2230.34732728
140SGK4940.34732728
141PTK20.34585549
142DYRK1B0.34224552
143STK380.34030026
144MAPKAPK50.33649774
145RPS6KA30.32883932
146PRKCI0.32639105
147CSNK1G20.32582568
148FYN0.32572796
149CCNB10.32315982
150MAPK120.32238661
151PDK10.31366829
152SRC0.31159194

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.93538076
2Ribosome_Homo sapiens_hsa030103.74800695
3Basal cell carcinoma_Homo sapiens_hsa052172.97097376
4Synaptic vesicle cycle_Homo sapiens_hsa047212.76668088
5Hedgehog signaling pathway_Homo sapiens_hsa043402.75459036
6Long-term potentiation_Homo sapiens_hsa047202.71173028
7Glutamatergic synapse_Homo sapiens_hsa047242.65793017
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.65362060
9Circadian entrainment_Homo sapiens_hsa047132.64281617
10Amphetamine addiction_Homo sapiens_hsa050312.61579979
11Olfactory transduction_Homo sapiens_hsa047402.39980895
12Salivary secretion_Homo sapiens_hsa049702.35753609
13Morphine addiction_Homo sapiens_hsa050322.32865914
14GABAergic synapse_Homo sapiens_hsa047272.29717748
15Notch signaling pathway_Homo sapiens_hsa043302.10647060
16Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.02168223
17alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.00773240
18Gastric acid secretion_Homo sapiens_hsa049711.95262915
19Linoleic acid metabolism_Homo sapiens_hsa005911.94389101
20Dopaminergic synapse_Homo sapiens_hsa047281.85234579
21Taste transduction_Homo sapiens_hsa047421.79361388
22Serotonergic synapse_Homo sapiens_hsa047261.79149304
23Hippo signaling pathway_Homo sapiens_hsa043901.77739742
24Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.74358066
25Fanconi anemia pathway_Homo sapiens_hsa034601.71313832
26Calcium signaling pathway_Homo sapiens_hsa040201.69512280
27Insulin secretion_Homo sapiens_hsa049111.66261801
28Long-term depression_Homo sapiens_hsa047301.64498763
29Cholinergic synapse_Homo sapiens_hsa047251.63977118
30Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.59133530
31Renin secretion_Homo sapiens_hsa049241.51395732
32Oxytocin signaling pathway_Homo sapiens_hsa049211.45504605
33Aldosterone synthesis and secretion_Homo sapiens_hsa049251.43914950
34Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.43128698
35Collecting duct acid secretion_Homo sapiens_hsa049661.41419457
36GnRH signaling pathway_Homo sapiens_hsa049121.36299361
37Cocaine addiction_Homo sapiens_hsa050301.33840905
38Sulfur relay system_Homo sapiens_hsa041221.31290826
39Axon guidance_Homo sapiens_hsa043601.30398761
40Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.29799196
41Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.29127905
42Gap junction_Homo sapiens_hsa045401.26105142
43Huntingtons disease_Homo sapiens_hsa050161.23078310
44Melanogenesis_Homo sapiens_hsa049161.20898208
45Oxidative phosphorylation_Homo sapiens_hsa001901.19554992
46African trypanosomiasis_Homo sapiens_hsa051431.18427176
47cAMP signaling pathway_Homo sapiens_hsa040241.17595890
48Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.14876169
49Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.10665754
50Estrogen signaling pathway_Homo sapiens_hsa049151.10229732
51Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.09692039
52Steroid biosynthesis_Homo sapiens_hsa001001.07414675
53Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.06642350
54Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.05555881
55Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.02804429
56Alcoholism_Homo sapiens_hsa050341.02564503
57Phosphatidylinositol signaling system_Homo sapiens_hsa040701.01026787
58ErbB signaling pathway_Homo sapiens_hsa040121.00547657
59Glioma_Homo sapiens_hsa052141.00538422
60Parkinsons disease_Homo sapiens_hsa050121.00115092
61Homologous recombination_Homo sapiens_hsa034400.95252167
62Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.93995853
63Dorso-ventral axis formation_Homo sapiens_hsa043200.91029892
64Ovarian steroidogenesis_Homo sapiens_hsa049130.90269423
65Type II diabetes mellitus_Homo sapiens_hsa049300.89122620
66Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.87788391
67Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.86483235
68Phototransduction_Homo sapiens_hsa047440.86162111
69cGMP-PKG signaling pathway_Homo sapiens_hsa040220.86008094
70Arachidonic acid metabolism_Homo sapiens_hsa005900.84767882
71VEGF signaling pathway_Homo sapiens_hsa043700.81452245
72Vibrio cholerae infection_Homo sapiens_hsa051100.80119351
73Phospholipase D signaling pathway_Homo sapiens_hsa040720.80055018
74Pancreatic secretion_Homo sapiens_hsa049720.79783406
75Vascular smooth muscle contraction_Homo sapiens_hsa042700.77936724
76Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.76973688
77Ether lipid metabolism_Homo sapiens_hsa005650.76114725
78Choline metabolism in cancer_Homo sapiens_hsa052310.75639568
79Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.75389140
80Basal transcription factors_Homo sapiens_hsa030220.74797655
81Lysine degradation_Homo sapiens_hsa003100.73699367
82Thyroid hormone synthesis_Homo sapiens_hsa049180.73149464
83Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.72943050
84Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.71536507
85Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.71066561
86Arginine and proline metabolism_Homo sapiens_hsa003300.70639737
87Ras signaling pathway_Homo sapiens_hsa040140.68574021
88FoxO signaling pathway_Homo sapiens_hsa040680.68289424
89MAPK signaling pathway_Homo sapiens_hsa040100.68152087
90Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.66644804
91Glycerolipid metabolism_Homo sapiens_hsa005610.64710339
92Caffeine metabolism_Homo sapiens_hsa002320.64061505
93Sphingolipid signaling pathway_Homo sapiens_hsa040710.61371476
94Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.60856314
95RNA degradation_Homo sapiens_hsa030180.59422142
96Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.59380689
97Chemokine signaling pathway_Homo sapiens_hsa040620.57800874
98Cardiac muscle contraction_Homo sapiens_hsa042600.57716794
99p53 signaling pathway_Homo sapiens_hsa041150.56694097
100Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.54921653
101Wnt signaling pathway_Homo sapiens_hsa043100.54899212
102Thyroid hormone signaling pathway_Homo sapiens_hsa049190.54630550
103Fat digestion and absorption_Homo sapiens_hsa049750.54268508
104RNA polymerase_Homo sapiens_hsa030200.54268149
105Melanoma_Homo sapiens_hsa052180.53333032
106Rap1 signaling pathway_Homo sapiens_hsa040150.52561012
107Glucagon signaling pathway_Homo sapiens_hsa049220.52339204
108Nucleotide excision repair_Homo sapiens_hsa034200.51633487
109Dilated cardiomyopathy_Homo sapiens_hsa054140.50267928
110Cyanoamino acid metabolism_Homo sapiens_hsa004600.49994358
111Oocyte meiosis_Homo sapiens_hsa041140.49923814
112Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.48963470
113Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.48464173
114Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.48112700
115Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.47943692
116Nitrogen metabolism_Homo sapiens_hsa009100.46456812
117AMPK signaling pathway_Homo sapiens_hsa041520.46355746
118Carbohydrate digestion and absorption_Homo sapiens_hsa049730.45964014
119Rheumatoid arthritis_Homo sapiens_hsa053230.45800704
120Peroxisome_Homo sapiens_hsa041460.45420711
121Fatty acid biosynthesis_Homo sapiens_hsa000610.45205501
122Neurotrophin signaling pathway_Homo sapiens_hsa047220.44804829
123Glycerophospholipid metabolism_Homo sapiens_hsa005640.44610007
124Tight junction_Homo sapiens_hsa045300.43854782
125Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.42737835
126Alzheimers disease_Homo sapiens_hsa050100.40235238
127Butanoate metabolism_Homo sapiens_hsa006500.40180086
128Prion diseases_Homo sapiens_hsa050200.39826862
129Type I diabetes mellitus_Homo sapiens_hsa049400.34951905
130Circadian rhythm_Homo sapiens_hsa047100.34757107
131Tuberculosis_Homo sapiens_hsa051520.32198320
132Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.31222646
133Inositol phosphate metabolism_Homo sapiens_hsa005620.30821528
134Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.30545162
135Prolactin signaling pathway_Homo sapiens_hsa049170.30523064
136Bile secretion_Homo sapiens_hsa049760.28314715
137Renal cell carcinoma_Homo sapiens_hsa052110.27845923
138Osteoclast differentiation_Homo sapiens_hsa043800.27665147
139Arginine biosynthesis_Homo sapiens_hsa002200.27054938
140Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.26470850
141Endometrial cancer_Homo sapiens_hsa052130.26056610
142Regulation of actin cytoskeleton_Homo sapiens_hsa048100.25987853
143Primary immunodeficiency_Homo sapiens_hsa053400.25755611

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »