FGD5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1lymph vessel development (GO:0001945)7.47657536
2endothelium development (GO:0003158)6.51162359
3vascular endothelial growth factor signaling pathway (GO:0038084)6.21405682
4lymphangiogenesis (GO:0001946)5.40797729
5cellular response to vascular endothelial growth factor stimulus (GO:0035924)5.26531968
6positive regulation of vasculogenesis (GO:2001214)5.16134116
7blood vessel maturation (GO:0001955)5.13423856
8retina vasculature morphogenesis in camera-type eye (GO:0061299)4.88650634
9surfactant homeostasis (GO:0043129)4.82034948
10ovulation from ovarian follicle (GO:0001542)4.75136964
11endothelial tube morphogenesis (GO:0061154)4.70613961
12morphogenesis of an endothelium (GO:0003159)4.70613961
13oxygen transport (GO:0015671)4.62192592
14regulation of endothelial cell differentiation (GO:0045601)4.56741439
15negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)4.52478340
16wound healing, spreading of epidermal cells (GO:0035313)4.45925612
17bundle of His cell to Purkinje myocyte communication (GO:0086069)4.42443388
18regulation of vasculogenesis (GO:2001212)4.37995099
19glomerular filtration (GO:0003094)4.36845434
20endothelial cell morphogenesis (GO:0001886)4.36490931
21venous blood vessel morphogenesis (GO:0048845)4.27569047
22renal filtration (GO:0097205)4.26162102
23heart trabecula formation (GO:0060347)4.10837424
24artery development (GO:0060840)4.04042765
25cardiac myofibril assembly (GO:0055003)4.01800228
26regulation of cell migration involved in sprouting angiogenesis (GO:0090049)4.00862416
27vascular endothelial growth factor receptor signaling pathway (GO:0048010)4.00526066
28embryonic heart tube development (GO:0035050)3.99657865
29blood vessel endothelial cell migration (GO:0043534)3.95082873
30patterning of blood vessels (GO:0001569)3.91035943
31endothelial cell differentiation (GO:0045446)3.88956466
32basement membrane organization (GO:0071711)3.88045774
33sprouting angiogenesis (GO:0002040)3.84188191
34cell migration involved in sprouting angiogenesis (GO:0002042)3.78840933
35vasculogenesis (GO:0001570)3.77764701
36Notch signaling involved in heart development (GO:0061314)3.72005049
37positive regulation of urine volume (GO:0035810)3.71765422
38chemical homeostasis within a tissue (GO:0048875)3.66304909
39coronary vasculature morphogenesis (GO:0060977)3.54487330
40gas transport (GO:0015669)3.49730314
41positive regulation of protein kinase C signaling (GO:0090037)3.48707468
42negative regulation of DNA biosynthetic process (GO:2000279)3.48453487
43regulation of establishment or maintenance of cell polarity (GO:0032878)3.43957140
44nephron epithelium development (GO:0072009)3.42475362
45neuron remodeling (GO:0016322)3.41937531
46positive regulation of glomerulus development (GO:0090193)3.41505567
47myofibril assembly (GO:0030239)3.37246599
48plasma membrane repair (GO:0001778)3.36360109
49negative regulation of endothelial cell migration (GO:0010596)3.35777990
50establishment of endothelial barrier (GO:0061028)3.35422380
51sarcomere organization (GO:0045214)3.34155959
52transcytosis (GO:0045056)3.33774116
53negative regulation of blood vessel endothelial cell migration (GO:0043537)3.32484426
54ventricular trabecula myocardium morphogenesis (GO:0003222)3.29828910
55axon extension involved in axon guidance (GO:0048846)3.29672786
56neuron projection extension involved in neuron projection guidance (GO:1902284)3.29672786
57fatty acid transmembrane transport (GO:1902001)3.27107831
58negative regulation of platelet activation (GO:0010544)3.25845622
59cell migration involved in heart development (GO:0060973)3.21231519
60negative regulation of vascular permeability (GO:0043116)3.19308685
61trabecula morphogenesis (GO:0061383)3.15764903
62regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030947)3.14690140
63carnitine shuttle (GO:0006853)3.12983618
64positive regulation of endothelial cell differentiation (GO:0045603)3.12625856
65negative regulation of focal adhesion assembly (GO:0051895)3.11560129
66negative regulation of cell junction assembly (GO:1901889)3.11560129
67negative regulation of adherens junction organization (GO:1903392)3.11560129
68peptidyl-tyrosine autophosphorylation (GO:0038083)3.08353515
69regulation of sarcomere organization (GO:0060297)3.06769184
70ventricular cardiac muscle tissue morphogenesis (GO:0055010)3.05645049
71heart trabecula morphogenesis (GO:0061384)3.05572880
72positive regulation of odontogenesis (GO:0042482)3.03996493
73positive regulation of pathway-restricted SMAD protein phosphorylation (GO:0010862)3.02684725
74negative regulation of endothelial cell apoptotic process (GO:2000352)3.01358136
75cAMP biosynthetic process (GO:0006171)3.00597151
76regulation of blood vessel endothelial cell migration (GO:0043535)2.99797941
77angiogenesis (GO:0001525)2.94412234
78regulation of vascular permeability (GO:0043114)2.92749752
79endothelial cell migration (GO:0043542)2.90675462
80regulation of urine volume (GO:0035809)2.88584580
81substrate-dependent cell migration (GO:0006929)2.88228960
82negative regulation of protein autophosphorylation (GO:0031953)2.87478561
83hemidesmosome assembly (GO:0031581)2.86575033
84negative regulation of actin filament bundle assembly (GO:0032232)2.86507107
85trabecula formation (GO:0060343)2.85928141
86glomerular visceral epithelial cell development (GO:0072015)2.85103159
87dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.84465421
88regulation of endothelial cell migration (GO:0010594)2.83270758
89regulation of actin filament-based movement (GO:1903115)2.83174614
90negative regulation of nitric-oxide synthase activity (GO:0051001)2.80500594
91definitive hemopoiesis (GO:0060216)2.79932145
92cardiac muscle tissue morphogenesis (GO:0055008)2.79140676
93regulation of p38MAPK cascade (GO:1900744)2.76884729
94cellular response to exogenous dsRNA (GO:0071360)2.74983509
95negative regulation of epithelial cell migration (GO:0010633)2.73607509
96negative regulation of macrophage derived foam cell differentiation (GO:0010745)2.73276250
97angiogenesis involved in wound healing (GO:0060055)2.72146584
98glomerular basement membrane development (GO:0032836)2.71874778
99plasma membrane fusion (GO:0045026)2.69123951
100arginine catabolic process (GO:0006527)2.69009079
101endothelial cell chemotaxis (GO:0035767)2.68772543
102cardiac muscle cell proliferation (GO:0060038)2.68666934
103ovulation (GO:0030728)2.68594114
104phagocytosis, recognition (GO:0006910)2.68568330
105negative regulation of angiogenesis (GO:0016525)2.68459369
106cyclic purine nucleotide metabolic process (GO:0052652)2.67224056
107blood vessel morphogenesis (GO:0048514)2.65848803
108blood vessel remodeling (GO:0001974)2.65050903
109thrombin receptor signaling pathway (GO:0070493)2.65031851
110adhesion of symbiont to host (GO:0044406)2.64450943
111negative regulation of blood vessel morphogenesis (GO:2000181)2.63818210
112positive regulation of cGMP biosynthetic process (GO:0030828)2.62835377
113negative regulation of endothelial cell proliferation (GO:0001937)2.61462093
114positive regulation of endothelial cell migration (GO:0010595)2.61314322
115positive regulation of endothelial cell proliferation (GO:0001938)2.61260233
116apoptotic cell clearance (GO:0043277)2.60276361
117ganglion development (GO:0061548)2.59936643
118negative regulation of Rho protein signal transduction (GO:0035024)2.57933197
119regulation of cardioblast differentiation (GO:0051890)2.56476951
120antigen processing and presentation of endogenous antigen (GO:0019883)2.55980309
121regulation of endothelial cell proliferation (GO:0001936)2.55766821
122muscle tissue morphogenesis (GO:0060415)2.55557696
123negative regulation of vasculature development (GO:1901343)2.54171804
124fibroblast migration (GO:0010761)2.53665335
125cyclic nucleotide biosynthetic process (GO:0009190)2.53428434
126cGMP biosynthetic process (GO:0006182)2.52468981
127regulation of relaxation of muscle (GO:1901077)2.51851173
128actomyosin structure organization (GO:0031032)2.51541959
129endothelial cell proliferation (GO:0001935)2.51084605
130regulation of cGMP biosynthetic process (GO:0030826)2.50008634
131negative regulation of nitric oxide biosynthetic process (GO:0045019)2.45314486
132keratan sulfate catabolic process (GO:0042340)2.43265325
133regulation of systemic arterial blood pressure by hormone (GO:0001990)2.42979875
134regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)2.42979875
135endocrine process (GO:0050886)2.42979875
136regulation of sequestering of triglyceride (GO:0010889)2.42416915
137wound healing, spreading of cells (GO:0044319)2.42049780
138positive regulation of cell junction assembly (GO:1901890)2.40685466
139positive regulation of focal adhesion assembly (GO:0051894)2.40685466
140mRNA transcription from RNA polymerase II promoter (GO:0042789)2.39295218
141regulation of focal adhesion assembly (GO:0051893)2.37818009
142regulation of cell-substrate junction assembly (GO:0090109)2.37818009
143atrial cardiac muscle cell action potential (GO:0086014)2.36994164

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.92202169
2TP63_17297297_ChIP-ChIP_HaCaT_Human3.81503999
3GATA2_21666600_ChIP-Seq_HMVEC_Human3.54267659
4TRIM28_21343339_ChIP-Seq_HEK293_Human3.30706357
5BP1_19119308_ChIP-ChIP_Hs578T_Human3.08336205
6CLOCK_20551151_ChIP-Seq_293T_Human2.90700141
7VDR_22108803_ChIP-Seq_LS180_Human2.85346368
8SMAD_19615063_ChIP-ChIP_OVARY_Human2.79811910
9EP300_21415370_ChIP-Seq_HL-1_Mouse2.58684796
10GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.52715372
11STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.27214929
12RARG_19884340_ChIP-ChIP_MEFs_Mouse2.18099457
13NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.17360565
14ESR1_21235772_ChIP-Seq_MCF-7_Human2.14656112
15TBX20_22080862_ChIP-Seq_HEART_Mouse2.09513085
16TBX20_22328084_ChIP-Seq_HEART_Mouse2.09513085
17EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.03381190
18ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.02107780
19ESR2_21235772_ChIP-Seq_MCF-7_Human1.96757339
20ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.96555649
21* ELK3_25401928_ChIP-Seq_HUVEC_Human1.96552519
22STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.88545754
23ZNF263_19887448_ChIP-Seq_K562_Human1.81296308
24EZH2_22144423_ChIP-Seq_EOC_Human1.78596052
25GATA1_22025678_ChIP-Seq_K562_Human1.76034703
26GBX2_23144817_ChIP-Seq_PC3_Human1.73394398
27KDM2B_26808549_Chip-Seq_SUP-B15_Human1.72760023
28GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.71805849
29ESR1_20079471_ChIP-ChIP_T-47D_Human1.68811289
30TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.68573052
31ZNF274_21170338_ChIP-Seq_K562_Hela1.66762411
32LXR_22158963_ChIP-Seq_LIVER_Mouse1.63857582
33TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.62258056
34SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.61850806
35SCL_19346495_ChIP-Seq_HPC-7_Human1.59572229
36CDX2_19796622_ChIP-Seq_MESCs_Mouse1.58362018
37THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.57843772
38GATA1_19941826_ChIP-Seq_K562_Human1.54755382
39RXR_22158963_ChIP-Seq_LIVER_Mouse1.49151431
40NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.48439868
41WT1_19549856_ChIP-ChIP_CCG9911_Human1.45555443
42TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.45442129
43ZNF217_24962896_ChIP-Seq_MCF-7_Human1.45121969
44ZFP57_27257070_Chip-Seq_ESCs_Mouse1.44723284
45HIF1A_21447827_ChIP-Seq_MCF-7_Human1.44332159
46PPAR_26484153_Chip-Seq_NCI-H1993_Human1.44242566
47BCAT_22108803_ChIP-Seq_LS180_Human1.39834111
48IRF8_22096565_ChIP-ChIP_GC-B_Human1.35684045
49* TCF4_18268006_ChIP-ChIP_LS174T_Human1.35556940
50FOXO3_23340844_ChIP-Seq_DLD1_Human1.34339669
51SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.32024164
52PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.31854297
53CJUN_26792858_Chip-Seq_BT549_Human1.30377851
54CDX2_20551321_ChIP-Seq_CACO-2_Human1.30135079
55SALL4_18804426_ChIP-ChIP_XEN_Mouse1.29585003
56MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.29128075
57BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.29078980
58RXR_22108803_ChIP-Seq_LS180_Human1.27074429
59P300_19829295_ChIP-Seq_ESCs_Human1.26901462
60* AHR_22903824_ChIP-Seq_MCF-7_Human1.25162018
61PPARA_22158963_ChIP-Seq_LIVER_Mouse1.24287638
62PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.21737991
63WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.21709987
64FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.20753373
65STAT6_21828071_ChIP-Seq_BEAS2B_Human1.19869746
66SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.19811981
67RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.18062624
68AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.17460564
69RNF2_18974828_ChIP-Seq_MESCs_Mouse1.16365274
70EZH2_18974828_ChIP-Seq_MESCs_Mouse1.16365274
71LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.16178758
72FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.15972650
73DROSHA_22980978_ChIP-Seq_HELA_Human1.15908211
74SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.13303453
75EED_16625203_ChIP-ChIP_MESCs_Mouse1.12799646
76KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.12553112
77KDM2B_26808549_Chip-Seq_K562_Human1.11462726
78SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.11349945
79CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.10637639
80ISL1_27105846_Chip-Seq_CPCs_Mouse1.09830112
81SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.09342174
82PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.09220252
83KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.09202407
84KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.09202407
85KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.09202407
86PIAS1_25552417_ChIP-Seq_VCAP_Human1.09187945
87PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.09163778
88NFIB_24661679_ChIP-Seq_LUNG_Mouse1.08206851
89SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.07503526
90SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.07503526
91IGF1R_20145208_ChIP-Seq_DFB_Human1.06646245
92SOX9_24532713_ChIP-Seq_HFSC_Mouse1.06583148
93IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.06493324
94SMAD3_21741376_ChIP-Seq_HESCs_Human1.06348905
95HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.05372636
96SMAD4_21799915_ChIP-Seq_A2780_Human1.05343900
97WT1_25993318_ChIP-Seq_PODOCYTE_Human1.04642530
98SMAD4_21741376_ChIP-Seq_HESCs_Human1.04539175
99* EZH2_27294783_Chip-Seq_ESCs_Mouse1.03861693
100BRD4_25478319_ChIP-Seq_HGPS_Human1.03298837
101RUNX_20019798_ChIP-Seq_JUKART_Human1.02834577
102* SOX2_20726797_ChIP-Seq_SW620_Human1.02379621
103UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.02039116
104PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.01279546
105* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.01151504
106RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.00599582
107SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.00531632
108GATA2_19941826_ChIP-Seq_K562_Human0.99423747
109KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.98564220
110SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.97750793
111ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.97497655
112TCF4_22108803_ChIP-Seq_LS180_Human0.96848699
113RNF2_27304074_Chip-Seq_ESCs_Mouse0.96800821
114* FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.96701918
115NRF2_20460467_ChIP-Seq_MEFs_Mouse0.96629000
116NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.96629000
117NR3C1_21868756_ChIP-Seq_MCF10A_Human0.96601166
118* TCF7_22412390_ChIP-Seq_EML_Mouse0.95936306
119VDR_24787735_ChIP-Seq_THP-1_Human0.95826611
120TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.95317250
121FOXA2_19822575_ChIP-Seq_HepG2_Human0.95210195
122SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.95096199
123GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.94564557
124KDM2B_26808549_Chip-Seq_DND41_Human0.94268421
125RUNX2_22187159_ChIP-Seq_PCA_Human0.93937594
126SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.93300274
127JARID2_20064375_ChIP-Seq_MESCs_Mouse0.93198241
128SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.92561596
129DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.92407169
130CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.92191931
131MEF2A_21415370_ChIP-Seq_HL-1_Mouse0.91977084
132EGR1_19374776_ChIP-ChIP_THP-1_Human0.91791611
133SMAD3_21741376_ChIP-Seq_EPCs_Human0.90615317
134LXR_22292898_ChIP-Seq_THP-1_Human0.89895524
135EZH2_27304074_Chip-Seq_ESCs_Mouse0.89629968
136* TCF4_23295773_ChIP-Seq_U87_Human0.89281091
137STAT3_23295773_ChIP-Seq_U87_Human0.88807096
138KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.88697772
139EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.88160703
140* ARNT_22903824_ChIP-Seq_MCF-7_Human0.88145335
141NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.87360692
142Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.86682422
143RUNX1_27514584_Chip-Seq_MCF-7_Human0.86565086
144AR_25329375_ChIP-Seq_VCAP_Human0.86375176
145NANOG_19829295_ChIP-Seq_ESCs_Human0.86326236
146SOX2_19829295_ChIP-Seq_ESCs_Human0.86326236
147JARID2_20075857_ChIP-Seq_MESCs_Mouse0.85090503
148SMAD4_21741376_ChIP-Seq_EPCs_Human0.84976112
149LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.84876758
150* TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.84859705
151RAD21_21589869_ChIP-Seq_MESCs_Mouse0.84849620
152NR3C1_23031785_ChIP-Seq_PC12_Mouse0.84170326
153* GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.83916338
154TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.83691774
155ELK4_26923725_Chip-Seq_MESODERM_Mouse0.83663459
156* SUZ12_27294783_Chip-Seq_ESCs_Mouse0.83199192

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010368_abnormal_lymphatic_system7.08989888
2MP0001879_abnormal_lymphatic_vessel5.35720525
3MP0002254_reproductive_system_inflammat4.26911318
4MP0005167_abnormal_blood-brain_barrier4.07501345
5MP0004272_abnormal_basement_membrane3.99749559
6MP0004084_abnormal_cardiac_muscle3.75278577
7MP0003828_pulmonary_edema3.15249175
8MP0000751_myopathy2.66819065
9MP0008775_abnormal_heart_ventricle2.52063011
10MP0000465_gastrointestinal_hemorrhage2.47004871
11MP0004036_abnormal_muscle_relaxation2.44956988
12MP0004215_abnormal_myocardial_fiber2.42728096
13MP0002837_dystrophic_cardiac_calcinosis2.39072804
14MP0006138_congestive_heart_failure2.34897585
15MP0002138_abnormal_hepatobiliary_system2.25464465
16MP0003724_increased_susceptibility_to2.23636602
17MP0006054_spinal_hemorrhage2.17575197
18MP0004510_myositis2.12312600
19MP0000767_abnormal_smooth_muscle2.04330922
20MP0005330_cardiomyopathy2.02354694
21MP0001544_abnormal_cardiovascular_syste1.97144191
22MP0005385_cardiovascular_system_phenoty1.97144191
23MP0003279_aneurysm1.95428291
24MP0002972_abnormal_cardiac_muscle1.80762025
25MP0002933_joint_inflammation1.79753942
26MP0010630_abnormal_cardiac_muscle1.77394937
27MP0003195_calcinosis1.77227264
28MP0004484_altered_response_of1.65236146
29MP0003705_abnormal_hypodermis_morpholog1.63659465
30MP0005623_abnormal_meninges_morphology1.61585451
31MP0003566_abnormal_cell_adhesion1.57918221
32MP0002127_abnormal_cardiovascular_syste1.55735632
33MP0004085_abnormal_heartbeat1.50053512
34MP0003303_peritoneal_inflammation1.49843238
35MP0005620_abnormal_muscle_contractility1.49505663
36MP0002128_abnormal_blood_circulation1.46317119
37MP0000749_muscle_degeneration1.42121750
38MP0002332_abnormal_exercise_endurance1.39525216
39MP0004087_abnormal_muscle_fiber1.38366353
40MP0009278_abnormal_bone_marrow1.38018037
41MP0003567_abnormal_fetal_cardiomyocyte1.32405533
42MP0000750_abnormal_muscle_regeneration1.30677539
43MP0002925_abnormal_cardiovascular_devel1.29812348
44MP0000343_altered_response_to1.28924677
45MP0004130_abnormal_muscle_cell1.28725823
46MP0005670_abnormal_white_adipose1.21483513
47MP0003646_muscle_fatigue1.20829913
48MP0005165_increased_susceptibility_to1.18021343
49MP0008004_abnormal_stomach_pH1.17950449
50MP0001348_abnormal_lacrimal_gland1.17648828
51MP0000249_abnormal_blood_vessel1.15222771
52MP0000266_abnormal_heart_morphology1.12940279
53MP0002106_abnormal_muscle_physiology1.11435542
54MP0001614_abnormal_blood_vessel1.11246570
55MP0003045_fibrosis1.10710567
56MP0001346_abnormal_lacrimal_gland1.08546104
57MP0009697_abnormal_copulation1.07852673
58MP0005595_abnormal_vascular_smooth1.05427673
59MP0000230_abnormal_systemic_arterial1.04987311
60MP0003950_abnormal_plasma_membrane1.04544695
61MP0003122_maternal_imprinting0.99467396
62MP0001958_emphysema0.98926732
63MP0004133_heterotaxia0.97177298
64MP0005187_abnormal_penis_morphology0.96395843
65MP0003943_abnormal_hepatobiliary_system0.92640061
66MP0005369_muscle_phenotype0.92551910
67MP0000003_abnormal_adipose_tissue0.90984823
68MP0004147_increased_porphyrin_level0.89304099
69MP0001851_eye_inflammation0.87767806
70MP0004808_abnormal_hematopoietic_stem0.87066483
71MP0005503_abnormal_tendon_morphology0.86316666
72MP0003091_abnormal_cell_migration0.86085825
73MP0003137_abnormal_impulse_conducting0.85858906
74MP0001784_abnormal_fluid_regulation0.81168421
75MP0003191_abnormal_cellular_cholesterol0.79813140
76MP0004782_abnormal_surfactant_physiolog0.79655873
77MP0002638_abnormal_pupillary_reflex0.79418502
78MP0005375_adipose_tissue_phenotype0.79346243
79MP0002876_abnormal_thyroid_physiology0.77721122
80MP0004883_abnormal_blood_vessel0.76663352
81MP0001873_stomach_inflammation0.76363512
82MP0000516_abnormal_urinary_system0.75062928
83MP0005367_renal/urinary_system_phenotyp0.75062928
84MP0009840_abnormal_foam_cell0.74880619
85MP0000013_abnormal_adipose_tissue0.74836791
86MP0002295_abnormal_pulmonary_circulatio0.73527536
87MP0000733_abnormal_muscle_development0.72453747
88MP0008438_abnormal_cutaneous_collagen0.71395969
89MP0005275_abnormal_skin_tensile0.71391178
90MP0001545_abnormal_hematopoietic_system0.69658239
91MP0005397_hematopoietic_system_phenotyp0.69658239
92MP0008961_abnormal_basal_metabolism0.68889854
93MP0005409_darkened_coat_color0.68872893
94MP0003221_abnormal_cardiomyocyte_apopto0.68557742
95MP0001915_intracranial_hemorrhage0.68134811
96MP0009764_decreased_sensitivity_to0.68107926
97MP0003868_abnormal_feces_composition0.67950443
98MP0000685_abnormal_immune_system0.67515094
99MP0003300_gastrointestinal_ulcer0.66634229
100MP0005647_abnormal_sex_gland0.65563197
101MP0002108_abnormal_muscle_morphology0.65018878
102MP0005164_abnormal_response_to0.64492039
103MP0000759_abnormal_skeletal_muscle0.64303155
104MP0002133_abnormal_respiratory_system0.64200672
105MP0005388_respiratory_system_phenotype0.64200672
106MP0003075_altered_response_to0.64082010
107MP0004145_abnormal_muscle_electrophysio0.63804784
108MP0005084_abnormal_gallbladder_morpholo0.63393421
109MP0005666_abnormal_adipose_tissue0.59125515
110MP0002998_abnormal_bone_remodeling0.58801949
111MP0009115_abnormal_fat_cell0.57981238
112MP0003252_abnormal_bile_duct0.57650252
113MP0002269_muscular_atrophy0.56532234
114MP0010030_abnormal_orbit_morphology0.56262255
115MP0000537_abnormal_urethra_morphology0.55365022
116MP0010234_abnormal_vibrissa_follicle0.55143242
117MP0006276_abnormal_autonomic_nervous0.54105952
118MP0002168_other_aberrant_phenotype0.53542032
119MP0002877_abnormal_melanocyte_morpholog0.53208349
120MP0002928_abnormal_bile_duct0.50020827
121MP0001533_abnormal_skeleton_physiology0.49568781
122MP0001501_abnormal_sleep_pattern0.49414140
123MP0002971_abnormal_brown_adipose0.48914005
124MP0003638_abnormal_response/metabolism_0.48070101
125MP0005410_abnormal_fertilization0.47145473
126MP0010329_abnormal_lipoprotein_level0.47076762
127MP0003119_abnormal_digestive_system0.46360905
128MP0005508_abnormal_skeleton_morphology0.44664306
129MP0003948_abnormal_gas_homeostasis0.43462304

Predicted human phenotypes

RankGene SetZ-score
1Polycythemia (HP:0001901)4.99792875
2Esophageal varix (HP:0002040)4.67335862
3Ventricular tachycardia (HP:0004756)4.63043904
4Hematochezia (HP:0002573)4.52051320
5Sudden death (HP:0001699)4.37401612
6Muscle fiber splitting (HP:0003555)4.27188692
7Spontaneous hematomas (HP:0007420)4.08627135
8Wrist flexion contracture (HP:0001239)4.07971133
9Increased connective tissue (HP:0009025)4.00098485
10Right ventricular cardiomyopathy (HP:0011663)3.91012932
11Atrial fibrillation (HP:0005110)3.85009062
12Lymphangioma (HP:0100764)3.80073310
13Broad metatarsal (HP:0001783)3.74094241
14Supraventricular arrhythmia (HP:0005115)3.62748625
15Primary atrial arrhythmia (HP:0001692)3.54396828
16Lipoatrophy (HP:0100578)3.47138953
17Abnormality of the nasal mucosa (HP:0000433)3.44229397
18Hyporeflexia of lower limbs (HP:0002600)3.38112360
19Supraventricular tachycardia (HP:0004755)3.37738460
20Cerebral aneurysm (HP:0004944)3.32204839
21Portal hypertension (HP:0001409)3.21869723
22Mesangial abnormality (HP:0001966)3.09590401
23Adactyly (HP:0009776)2.99889720
24Skull defect (HP:0001362)2.97750212
25Absent hand (HP:0004050)2.97611277
26Abnormality of the hepatic vasculature (HP:0006707)2.93734083
27Systemic lupus erythematosus (HP:0002725)2.89846408
28Difficulty running (HP:0009046)2.89026165
29Nonimmune hydrops fetalis (HP:0001790)2.86513886
30Exercise-induced myalgia (HP:0003738)2.86207892
31Cerebral hemorrhage (HP:0001342)2.83542100
32Dilated cardiomyopathy (HP:0001644)2.81489930
33Increased variability in muscle fiber diameter (HP:0003557)2.81408887
34Hemiplegia (HP:0002301)2.81148016
35Abnormality of skeletal muscle fiber size (HP:0012084)2.80136302
36Atrioventricular block (HP:0001678)2.75011560
37Visceral angiomatosis (HP:0100761)2.67158230
38Hemangiomatosis (HP:0007461)2.64228801
39Calf muscle hypertrophy (HP:0008981)2.63532616
40Pulmonary hypertension (HP:0002092)2.63198596
41Rectal prolapse (HP:0002035)2.60142602
42Deep venous thrombosis (HP:0002625)2.59506636
43Abnormality of the left ventricular outflow tract (HP:0011103)2.59305770
44Subaortic stenosis (HP:0001682)2.59305770
45Conjunctival telangiectasia (HP:0000524)2.58834093
46Porencephaly (HP:0002132)2.58158927
47High pitched voice (HP:0001620)2.55088865
48Bulbous nose (HP:0000414)2.54874963
49Palpitations (HP:0001962)2.52452573
50Aortic aneurysm (HP:0004942)2.50322144
51EMG: myopathic abnormalities (HP:0003458)2.48675243
52Exercise-induced muscle cramps (HP:0003710)2.48150659
53Aplasia cutis congenita (HP:0001057)2.46168372
54Complement deficiency (HP:0004431)2.44939946
55Congenital, generalized hypertrichosis (HP:0004540)2.44904376
56Abnormality of glycosphingolipid metabolism (HP:0004343)2.44105388
57Abnormality of glycolipid metabolism (HP:0010969)2.44105388
58Abnormality of liposaccharide metabolism (HP:0010968)2.44105388
59Myotonia (HP:0002486)2.43095089
60Aneurysm (HP:0002617)2.42419151
61Hip contracture (HP:0003273)2.42270324
62Increased neuronal autofluorescent lipopigment (HP:0002074)2.40783707
63Asymmetry of the thorax (HP:0001555)2.40587626
64Pulmonary artery stenosis (HP:0004415)2.38984090
65Protrusio acetabuli (HP:0003179)2.38573214
66Pigmentary retinal degeneration (HP:0001146)2.38304051
67Delayed CNS myelination (HP:0002188)2.36688986
68Scotoma (HP:0000575)2.36447182
69Aortic valve stenosis (HP:0001650)2.35806525
70Cavernous hemangioma (HP:0001048)2.32327408
71Abnormality of the calf musculature (HP:0001430)2.32076312
72Myocardial infarction (HP:0001658)2.31863753
73Prolonged QT interval (HP:0001657)2.31738842
74Heart block (HP:0012722)2.30268582
75Hemorrhage of the eye (HP:0011885)2.28996438
76Alveolar cell carcinoma (HP:0006519)2.27653335
77Muscle hypertrophy of the lower extremities (HP:0008968)2.26592023
78Spinal rigidity (HP:0003306)2.26094701
79Colitis (HP:0002583)2.24060635
80Venous insufficiency (HP:0005293)2.23044134
81Congenital hepatic fibrosis (HP:0002612)2.22747296
82Decreased circulating renin level (HP:0003351)2.22031788
83Myoglobinuria (HP:0002913)2.21717989
84Increased cerebral lipofuscin (HP:0011813)2.20367971
85Tetraparesis (HP:0002273)2.19686510
86Abnormal atrioventricular conduction (HP:0005150)2.19128743
87Asymmetric septal hypertrophy (HP:0001670)2.17379042
88Syncope (HP:0001279)2.16680321
89Bundle branch block (HP:0011710)2.13722569
90Stroke (HP:0001297)2.13325239
91Advanced eruption of teeth (HP:0006288)2.13131100
92Facial diplegia (HP:0001349)2.12647425
93Capillary hemangiomas (HP:0005306)2.12211220
94Difficulty climbing stairs (HP:0003551)2.11626407
95Abnormality of the vasculature of the conjunctiva (HP:0008054)2.07134513
96Increased corneal curvature (HP:0100692)2.06584069
97Keratoconus (HP:0000563)2.06584069
98Focal segmental glomerulosclerosis (HP:0000097)2.05922182
99Distal lower limb muscle weakness (HP:0009053)2.05548112
100Bone cyst (HP:0012062)2.05230824
101Oligomenorrhea (HP:0000876)2.02629440
102Milia (HP:0001056)2.01762033
103Hypoplastic ischia (HP:0003175)2.01348429
104Joint hemorrhage (HP:0005261)1.99751750
105Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.99198550
106Short 4th metacarpal (HP:0010044)1.99198550
107Mucosal telangiectasiae (HP:0100579)1.99154689
108Distal arthrogryposis (HP:0005684)1.98982826
109Glomerulonephritis (HP:0000099)1.96676016
110Ectopia lentis (HP:0001083)1.96535868
111Venous abnormality (HP:0002624)1.94614490
112Neonatal death (HP:0003811)1.94391707
113Weak cry (HP:0001612)1.93869881
114Generalized muscle weakness (HP:0003324)1.93020869
115Abnormality of the periventricular white matter (HP:0002518)1.92992893
116Ventricular arrhythmia (HP:0004308)1.92718488
117Abnormality of the ischium (HP:0003174)1.92411829
118Hemoptysis (HP:0002105)1.92284024
119Congenital stationary night blindness (HP:0007642)1.92139095
120Joint stiffness (HP:0001387)1.91696790
121Neoplasm of the tracheobronchial system (HP:0100552)1.90816395
122Lymphedema (HP:0001004)1.90644402
123Limited hip movement (HP:0008800)1.87467048
124Polygenic inheritance (HP:0010982)1.87207755
125Growth hormone excess (HP:0000845)1.87057819
126Type 1 muscle fiber predominance (HP:0003803)1.84462181
127Abnormality of the gastric mucosa (HP:0004295)1.84341620
128Vacuolated lymphocytes (HP:0001922)1.83846613
129Keratoconjunctivitis (HP:0001096)1.83749132
130Short hallux (HP:0010109)1.83608592
131Ulnar claw (HP:0001178)1.83164062
132Abnormality of the 4th metacarpal (HP:0010012)1.82979202
133Hypoglycemic coma (HP:0001325)1.81822500
134Clumsiness (HP:0002312)1.81326934
135Hemiparesis (HP:0001269)1.80679951
136Hyperventilation (HP:0002883)1.80478040
137Facial shape deformation (HP:0011334)1.78901650
138Potter facies (HP:0002009)1.78901650
139Atrophic scars (HP:0001075)1.78713346
140Exotropia (HP:0000577)1.78353409
141Autoimmune thrombocytopenia (HP:0001973)1.77927480
142Hypoplasia of the iris (HP:0007676)1.76770322
143Abolished electroretinogram (ERG) (HP:0000550)1.75965643
144Limb-girdle muscle atrophy (HP:0003797)1.75803546
145Aortic dissection (HP:0002647)1.75535662
146Mitral valve prolapse (HP:0001634)1.74648568
147Hypercortisolism (HP:0001578)1.73638306
148Natal tooth (HP:0000695)1.73388392
149Thrombophlebitis (HP:0004418)1.73355653
150Tubulointerstitial fibrosis (HP:0005576)1.73240733
151Aplasia/Hypoplasia of the spleen (HP:0010451)1.73197929
152Neoplasm of the heart (HP:0100544)1.71670389
153Absent toe (HP:0010760)1.70024220
154Nephritis (HP:0000123)1.69031618

Predicted kinase interactions (KEA)

RankGene SetZ-score
1KDR5.59600427
2TGFBR23.90951213
3TGFBR13.52271939
4RIPK12.45552518
5FES2.17727019
6MYLK2.01584965
7TIE110.0598381
8EPHB21.95840444
9TTN1.86575368
10PKN21.72526280
11FGFR41.65096241
12PDK21.53049561
13FRK1.51076898
14PTK61.48704053
15PTK2B1.47589074
16FER1.35561268
17FGFR31.35127165
18ACVR1B1.34138922
19BMPR1B1.30735672
20ERN11.27518473
21EPHB11.25032764
22TAOK31.24938185
23MAPKAPK31.21915381
24MAP3K131.21494845
25INSRR1.21049961
26BCKDK1.19760439
27MAP3K141.17253621
28PDGFRA1.14664704
29ADRBK21.11122362
30MAP2K31.10884135
31TRIB31.10779973
32DMPK1.06467247
33EPHA31.04139764
34MAPK121.02691386
35OBSCN1.00976826
36TAF10.99537124
37GRK10.99097856
38PRKG20.98971183
39PHKG20.98434699
40PHKG10.98434699
41PINK10.94009509
42MAP3K70.91684797
43PRKD10.86897032
44TRPM70.86540501
45LMTK20.85258316
46DAPK20.83269904
47PRKAA20.82583362
48STK38L0.81044651
49ITK0.80953861
50JAK30.77782830
51SIK10.77108331
52PAK40.69671725
53CAMK40.68788592
54BLK0.68560098
55LATS10.67557054
56FGFR20.67151239
57CAMK1D0.65672203
58CHUK0.65038186
59MAPK70.64649849
60LRRK20.62547193
61STK240.60248796
62MAPK150.59375212
63PTK20.56525507
64TBK10.55244942
65MAPKAPK50.54636215
66FLT30.53434860
67CAMK1G0.52336216
68PIK3CG0.51454969
69WNK40.51313355
70RET0.50977670
71MAP3K30.50612812
72ZAK0.49995400
73EEF2K0.49843365
74NLK0.49537391
75NUAK10.49319984
76RPS6KA20.48993178
77PIK3CA0.47881832
78DYRK30.46466883
79TLK10.46361232
80TEC0.45793668
81KIT0.44671548
82DYRK1B0.44033298
83ZAP700.43607319
84OXSR10.43429517
85WNK30.41703558
86PRKCH0.40344077
87ADRBK10.40108210
88IKBKE0.39714726
89TNIK0.38889832
90CAMKK20.38341261
91GSK3A0.37985361
92MAP4K10.37669682
93GRK50.37073128
94JAK20.37057369
95IGF1R0.36950443
96HCK0.35908776
97CSNK1G10.35577497
98CAMK10.35357073
99PDGFRB0.35110764
100MET0.34350726
101SGK20.34171948
102PAK20.34091563
103CDC42BPA0.33350587
104JAK10.33335272
105AKT30.33043689
106PDK40.32597133
107PDK30.32597133
108LATS20.32082095
109EGFR0.31828486
110PRKAA10.31368786
111SRC0.31139082
112NTRK10.30822778
113PRKG10.30714644
114MTOR0.30423534
115CDK80.29159860
116FGFR10.28897250
117MAP3K10.27974716
118CSK0.26433887
119STK100.26263780
120PRKCE0.25639101
121ROCK10.25418473
122MAP2K60.24508767
123AKT20.24104546
124MAPK130.24077945
125MAP3K60.24034422
126CDK30.23440336
127TYK20.23276517
128LCK0.23024466
129PDPK10.21787929
130BTK0.21447183
131PRKD20.20894362
132ABL20.20763333
133STK390.20749338
134SGK4940.20013656
135SGK2230.20013656
136MATK0.19944745
137MAP2K10.19807552
138MAP3K110.19571713
139CLK10.19321034
140NME10.19209145
141DDR20.19027576
142MARK20.18659268
143MAPK40.18497366
144EPHA20.17370290
145RPS6KA60.17242001

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycosaminoglycan degradation_Homo sapiens_hsa005313.05688809
2Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.78723244
3ECM-receptor interaction_Homo sapiens_hsa045122.74068168
4Dilated cardiomyopathy_Homo sapiens_hsa054142.71750108
5Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.55521084
6Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.50006276
7Linoleic acid metabolism_Homo sapiens_hsa005912.47863240
8Focal adhesion_Homo sapiens_hsa045102.24461445
9Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.21512147
10alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.20797707
11Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.16743090
12Arginine biosynthesis_Homo sapiens_hsa002202.11262456
13Adherens junction_Homo sapiens_hsa045202.05826042
14Staphylococcus aureus infection_Homo sapiens_hsa051502.00692983
15Fatty acid degradation_Homo sapiens_hsa000711.90437717
16AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.79114594
17Leukocyte transendothelial migration_Homo sapiens_hsa046701.72432624
18Propanoate metabolism_Homo sapiens_hsa006401.69419951
19Insulin resistance_Homo sapiens_hsa049311.68506483
20Intestinal immune network for IgA production_Homo sapiens_hsa046721.63371278
21Small cell lung cancer_Homo sapiens_hsa052221.62181447
222-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.62103476
23Viral myocarditis_Homo sapiens_hsa054161.60141419
24Ether lipid metabolism_Homo sapiens_hsa005651.57506098
25Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.53085028
26Rheumatoid arthritis_Homo sapiens_hsa053231.51540596
27PPAR signaling pathway_Homo sapiens_hsa033201.45632105
28Arachidonic acid metabolism_Homo sapiens_hsa005901.43562969
29Amoebiasis_Homo sapiens_hsa051461.40414772
30Tryptophan metabolism_Homo sapiens_hsa003801.39186854
31Complement and coagulation cascades_Homo sapiens_hsa046101.36400121
32Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.33740402
33Rap1 signaling pathway_Homo sapiens_hsa040151.32988198
34African trypanosomiasis_Homo sapiens_hsa051431.32455776
35Adipocytokine signaling pathway_Homo sapiens_hsa049201.31041925
36Lysosome_Homo sapiens_hsa041421.30765216
37Protein digestion and absorption_Homo sapiens_hsa049741.30595702
38Phototransduction_Homo sapiens_hsa047441.30001482
39Platelet activation_Homo sapiens_hsa046111.29492578
40Notch signaling pathway_Homo sapiens_hsa043301.27421100
41Histidine metabolism_Homo sapiens_hsa003401.23891299
42Dorso-ventral axis formation_Homo sapiens_hsa043201.22808487
43Fatty acid metabolism_Homo sapiens_hsa012121.20300241
44PI3K-Akt signaling pathway_Homo sapiens_hsa041511.20052130
45Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.19099097
46Toxoplasmosis_Homo sapiens_hsa051451.19000299
47Bile secretion_Homo sapiens_hsa049761.12841225
48Tight junction_Homo sapiens_hsa045301.09442875
49Vascular smooth muscle contraction_Homo sapiens_hsa042701.08029580
50Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.07740531
51Serotonergic synapse_Homo sapiens_hsa047261.05839461
52Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.05529237
53Nitrogen metabolism_Homo sapiens_hsa009101.02446714
54Pertussis_Homo sapiens_hsa051331.00497867
55Cardiac muscle contraction_Homo sapiens_hsa042600.99450850
56Proteoglycans in cancer_Homo sapiens_hsa052050.98341353
57Selenocompound metabolism_Homo sapiens_hsa004500.97663018
58Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.96536579
59cGMP-PKG signaling pathway_Homo sapiens_hsa040220.93945629
60Renin secretion_Homo sapiens_hsa049240.93104414
61Pathways in cancer_Homo sapiens_hsa052000.92673995
62Glycerolipid metabolism_Homo sapiens_hsa005610.90420616
63Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.89523263
64Allograft rejection_Homo sapiens_hsa053300.89495660
65Ovarian steroidogenesis_Homo sapiens_hsa049130.89191391
66Glycerophospholipid metabolism_Homo sapiens_hsa005640.88269794
67HIF-1 signaling pathway_Homo sapiens_hsa040660.86365517
68Mineral absorption_Homo sapiens_hsa049780.86075193
69Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.85211639
70Lysine degradation_Homo sapiens_hsa003100.84145943
71Autoimmune thyroid disease_Homo sapiens_hsa053200.83656139
72Hematopoietic cell lineage_Homo sapiens_hsa046400.83257744
73Primary bile acid biosynthesis_Homo sapiens_hsa001200.81917371
74Glucagon signaling pathway_Homo sapiens_hsa049220.80784437
75Taste transduction_Homo sapiens_hsa047420.80627130
76Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.79603325
77Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.78437340
78Retinol metabolism_Homo sapiens_hsa008300.76275572
79TNF signaling pathway_Homo sapiens_hsa046680.75739591
80Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.75722848
81Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.75702088
82Malaria_Homo sapiens_hsa051440.75061787
83Graft-versus-host disease_Homo sapiens_hsa053320.74960131
84Sulfur metabolism_Homo sapiens_hsa009200.74307336
85Gap junction_Homo sapiens_hsa045400.73125335
86VEGF signaling pathway_Homo sapiens_hsa043700.73056837
87Chemical carcinogenesis_Homo sapiens_hsa052040.73034929
88Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.72418845
89Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.71946551
90TGF-beta signaling pathway_Homo sapiens_hsa043500.71598303
91Basal cell carcinoma_Homo sapiens_hsa052170.71503923
92Thyroid hormone signaling pathway_Homo sapiens_hsa049190.70016887
93Ras signaling pathway_Homo sapiens_hsa040140.69286718
94Other glycan degradation_Homo sapiens_hsa005110.69240444
95Aldosterone synthesis and secretion_Homo sapiens_hsa049250.69112052
96Caffeine metabolism_Homo sapiens_hsa002320.68110820
97Axon guidance_Homo sapiens_hsa043600.67545931
98Asthma_Homo sapiens_hsa053100.67465684
99Salivary secretion_Homo sapiens_hsa049700.66205599
100Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.66125643
101Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.65647768
102Phagosome_Homo sapiens_hsa041450.63161349
103Phenylalanine metabolism_Homo sapiens_hsa003600.61667153
104ABC transporters_Homo sapiens_hsa020100.61657909
105Renin-angiotensin system_Homo sapiens_hsa046140.61602451
106Type I diabetes mellitus_Homo sapiens_hsa049400.59806491
107Leishmaniasis_Homo sapiens_hsa051400.59433425
108Osteoclast differentiation_Homo sapiens_hsa043800.59261117
109Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.57888157
110Morphine addiction_Homo sapiens_hsa050320.57846896
111Insulin secretion_Homo sapiens_hsa049110.56481244
112MicroRNAs in cancer_Homo sapiens_hsa052060.56476356
113NF-kappa B signaling pathway_Homo sapiens_hsa040640.56437408
114AMPK signaling pathway_Homo sapiens_hsa041520.56429538
115Melanogenesis_Homo sapiens_hsa049160.56213831
116Long-term depression_Homo sapiens_hsa047300.55972794
117Gastric acid secretion_Homo sapiens_hsa049710.55510543
118Jak-STAT signaling pathway_Homo sapiens_hsa046300.55400233
119Pyruvate metabolism_Homo sapiens_hsa006200.55205865
120Maturity onset diabetes of the young_Homo sapiens_hsa049500.55187913
121Vitamin digestion and absorption_Homo sapiens_hsa049770.55153229
122Regulation of actin cytoskeleton_Homo sapiens_hsa048100.54917568
123Longevity regulating pathway - mammal_Homo sapiens_hsa042110.54756504
124Circadian entrainment_Homo sapiens_hsa047130.53743936
125Steroid hormone biosynthesis_Homo sapiens_hsa001400.53541399
126Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.53439940
127Glutamatergic synapse_Homo sapiens_hsa047240.53291940
128Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.53046088
129Hippo signaling pathway_Homo sapiens_hsa043900.53021197
130Olfactory transduction_Homo sapiens_hsa047400.52931199
131Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.52774651
132Butanoate metabolism_Homo sapiens_hsa006500.52533937
133cAMP signaling pathway_Homo sapiens_hsa040240.52240799
134Calcium signaling pathway_Homo sapiens_hsa040200.51772055
135Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.51268620
136Transcriptional misregulation in cancer_Homo sapiens_hsa052020.51113259
137Oxytocin signaling pathway_Homo sapiens_hsa049210.48894988
138Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.48697784
139Fat digestion and absorption_Homo sapiens_hsa049750.48106032
140Starch and sucrose metabolism_Homo sapiens_hsa005000.46411751
141RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.46390082
142HTLV-I infection_Homo sapiens_hsa051660.43831905
143Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.43421328
144Insulin signaling pathway_Homo sapiens_hsa049100.43292579
145Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.42392285
146Estrogen signaling pathway_Homo sapiens_hsa049150.41780747
147Hepatitis C_Homo sapiens_hsa051600.41609402
148Circadian rhythm_Homo sapiens_hsa047100.40760930
149Phospholipase D signaling pathway_Homo sapiens_hsa040720.39868960
150Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.37933331

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