FGFR1OP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.52370230
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.52370230
3antigen processing and presentation of endogenous antigen (GO:0019883)5.80128368
4positive regulation of gamma-delta T cell activation (GO:0046645)5.66822354
5negative regulation of cell killing (GO:0031342)5.66239484
6negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.66239484
7antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.85908388
8positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.80377973
9regulation of gamma-delta T cell differentiation (GO:0045586)4.47844600
10antigen processing and presentation via MHC class Ib (GO:0002475)4.23921361
11regulation of B cell receptor signaling pathway (GO:0050855)4.14463732
12positive regulation of B cell differentiation (GO:0045579)4.09606787
13regulation of gamma-delta T cell activation (GO:0046643)3.96652774
14response to interleukin-15 (GO:0070672)3.95719539
15positive regulation of alpha-beta T cell proliferation (GO:0046641)3.94986331
16Arp2/3 complex-mediated actin nucleation (GO:0034314)3.89096289
17ribosomal small subunit assembly (GO:0000028)3.85036117
18positive regulation of granulocyte differentiation (GO:0030854)3.80142371
19B cell receptor signaling pathway (GO:0050853)3.78562018
20negative regulation of neurotransmitter transport (GO:0051589)3.67512775
21negative T cell selection (GO:0043383)3.67214530
22regulation of B cell differentiation (GO:0045577)3.65914334
23mast cell activation (GO:0045576)3.65480239
24interferon-gamma production (GO:0032609)3.62221479
25nerve growth factor signaling pathway (GO:0038180)3.60811753
26cellular response to interleukin-15 (GO:0071350)3.55526453
27definitive hemopoiesis (GO:0060216)3.50307841
28negative regulation of calcium ion-dependent exocytosis (GO:0045955)3.49788462
29cell wall macromolecule catabolic process (GO:0016998)3.48637687
30negative thymic T cell selection (GO:0045060)3.44385744
31negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.42776252
32negative regulation of T-helper cell differentiation (GO:0045623)3.42776252
33negative regulation of phagocytosis (GO:0050765)3.41725553
34positive regulation of vasculogenesis (GO:2001214)3.37325099
35defense response to protozoan (GO:0042832)3.34324176
36regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.34141712
37response to protozoan (GO:0001562)3.28050481
38regulation of platelet aggregation (GO:0090330)3.27227477
39negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.24950449
40negative regulation of neurotransmitter secretion (GO:0046929)3.23869072
41relaxation of smooth muscle (GO:0044557)3.20629190
42T cell homeostasis (GO:0043029)3.20434143
43mast cell activation involved in immune response (GO:0002279)3.19208822
44mast cell degranulation (GO:0043303)3.19208822
45megakaryocyte development (GO:0035855)3.18206910
46cell wall macromolecule metabolic process (GO:0044036)3.12120474
47positive regulation of lamellipodium assembly (GO:0010592)3.10569372
48regulation of T cell receptor signaling pathway (GO:0050856)3.10448657
49leukocyte aggregation (GO:0070486)3.09540525
50histamine secretion (GO:0001821)3.08507320
51regulation of T cell mediated cytotoxicity (GO:0001914)3.04829403
52neutrophil mediated immunity (GO:0002446)3.01835541
53actin nucleation (GO:0045010)3.01068211
54positive regulation of interleukin-17 production (GO:0032740)2.99457818
55response to pheromone (GO:0019236)2.98728531
56negative regulation of erythrocyte differentiation (GO:0045647)2.98710726
57hepatocyte apoptotic process (GO:0097284)2.97369248
58necroptotic process (GO:0070266)2.96597218
59positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)2.94130905
60Rap protein signal transduction (GO:0032486)2.93060313
61signal peptide processing (GO:0006465)2.92263931
62regulation of inositol phosphate biosynthetic process (GO:0010919)2.92130006
63myeloid cell development (GO:0061515)2.90599129
64neutrophil activation (GO:0042119)2.90359945
65positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.90203918
66regulation of response to interferon-gamma (GO:0060330)2.89843487
67antigen receptor-mediated signaling pathway (GO:0050851)2.89042318
68regulation of germinal center formation (GO:0002634)2.86675824
69regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.86641599
70regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.83426052
71regulation of regulatory T cell differentiation (GO:0045589)2.83108315
72regulation of T-helper 1 cell differentiation (GO:0045625)2.82581550
73regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)2.82188575
74negative regulation of T cell receptor signaling pathway (GO:0050860)2.81568529
75natural killer cell mediated immunity (GO:0002228)2.80657160
76natural killer cell mediated cytotoxicity (GO:0042267)2.80657160
77ncRNA 3-end processing (GO:0043628)2.80540529
78negative regulation of exocytosis (GO:0045920)2.77724564
79immunoglobulin mediated immune response (GO:0016064)2.77534805
80Peyers patch development (GO:0048541)2.76694141
81mucosal-associated lymphoid tissue development (GO:0048537)2.76694141
82negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.75820810
83regulation of necroptotic process (GO:0060544)2.75762659
84regulation of interleukin-17 production (GO:0032660)2.75664192
85myeloid leukocyte mediated immunity (GO:0002444)2.75579062
86G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.75560174
87negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.75332636
88leukocyte degranulation (GO:0043299)2.73608424
89positive regulation of mast cell activation (GO:0033005)2.73317256
90lymphocyte homeostasis (GO:0002260)2.73241951
91lymph node development (GO:0048535)2.71510781
92regulation of memory T cell differentiation (GO:0043380)2.71395910
93positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.70834558
94T cell selection (GO:0045058)2.69553659
95SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.68483345
96purine-containing compound salvage (GO:0043101)2.67371038
97positive regulation of macrophage differentiation (GO:0045651)2.65612166
98regulation of mast cell activation (GO:0033003)2.64827005
99phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.64642634
100positive T cell selection (GO:0043368)2.64003760
101interferon-gamma-mediated signaling pathway (GO:0060333)2.64002531
102microglial cell activation (GO:0001774)2.63686661
103thrombin receptor signaling pathway (GO:0070493)2.63658494
104T cell receptor signaling pathway (GO:0050852)2.63377349
105response to type I interferon (GO:0034340)2.63290373
106mitochondrial DNA replication (GO:0006264)2.63182258
107COPI coating of Golgi vesicle (GO:0048205)2.63082786
108Golgi transport vesicle coating (GO:0048200)2.63082786
109regulation of mast cell degranulation (GO:0043304)2.62961318
110viral transcription (GO:0019083)2.61188471
111B cell mediated immunity (GO:0019724)2.60467350
112negative regulation of adaptive immune response (GO:0002820)2.60066034
113regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)2.60030643
114cotranslational protein targeting to membrane (GO:0006613)2.59430916
115positive regulation of lamellipodium organization (GO:1902745)2.59328984
116positive regulation of alpha-beta T cell activation (GO:0046635)2.59201946
117protein targeting to ER (GO:0045047)2.59112203
118sleep (GO:0030431)2.58948487
119T cell migration (GO:0072678)2.58737424
120positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.58693395
121protein localization to endoplasmic reticulum (GO:0070972)2.58340028
122negative regulation of lymphocyte mediated immunity (GO:0002707)2.58300106
123regulation of mast cell activation involved in immune response (GO:0033006)2.58225225
124cellular response to type I interferon (GO:0071357)2.57504298
125type I interferon signaling pathway (GO:0060337)2.57504298
126regulation of alpha-beta T cell activation (GO:0046634)2.57103258
127positive thymic T cell selection (GO:0045059)2.57075194
128cellular response to zinc ion (GO:0071294)2.56378251
129granulocyte activation (GO:0036230)2.55797852
130DNA deamination (GO:0045006)2.55438855
131rRNA methylation (GO:0031167)2.55192956
132translational termination (GO:0006415)2.54251098
133positive regulation of natural killer cell differentiation (GO:0032825)2.53603384
134response to peptidoglycan (GO:0032494)2.53459820
135myeloid dendritic cell activation (GO:0001773)2.52574439
136leukocyte homeostasis (GO:0001776)2.52445261
137natural killer cell differentiation (GO:0001779)2.52354222
138negative regulation of B cell proliferation (GO:0030889)2.51195996
139ribonucleoprotein complex disassembly (GO:0032988)2.51117508
140T cell proliferation (GO:0042098)2.50870745
141regulation of interleukin-12 biosynthetic process (GO:0045075)2.50647646
142neutrophil activation involved in immune response (GO:0002283)2.50587291
143tolerance induction (GO:0002507)2.50373004
144negative regulation of T cell mediated immunity (GO:0002710)2.50050408
145angiogenesis involved in wound healing (GO:0060055)2.49193785
146establishment of protein localization to endoplasmic reticulum (GO:0072599)2.49182211
147regulation of erythrocyte differentiation (GO:0045646)2.48972338
148detection of other organism (GO:0098543)2.48659764
149positive regulation of DNA recombination (GO:0045911)2.48638202
150thymic T cell selection (GO:0045061)2.47659644
151regulation of granulocyte differentiation (GO:0030852)2.46785112
152positive regulation of Rap GTPase activity (GO:0032854)2.46277399
153hemoglobin metabolic process (GO:0020027)2.46193656
154cellular extravasation (GO:0045123)2.46192597
155regulation of T-helper cell differentiation (GO:0045622)2.46117065
156response to interferon-beta (GO:0035456)2.45669851
157regulation of alpha-beta T cell proliferation (GO:0046640)2.44987496
158alpha-beta T cell activation (GO:0046631)2.43604044
159tRNA methylation (GO:0030488)2.43379574
160purinergic nucleotide receptor signaling pathway (GO:0035590)2.43242369
161regulation of leukocyte mediated cytotoxicity (GO:0001910)2.43233820
162embryonic hemopoiesis (GO:0035162)2.42812870
163natural killer cell activation (GO:0030101)2.42435228
164mature B cell differentiation involved in immune response (GO:0002313)2.41931258
165mature B cell differentiation (GO:0002335)2.41918845

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.76206966
2IRF8_22096565_ChIP-ChIP_GC-B_Human3.77013229
3GATA1_22025678_ChIP-Seq_K562_Human3.46503675
4* STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.45878769
5MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.27352432
6* IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.17385138
7SCL_19346495_ChIP-Seq_HPC-7_Human3.05778929
8EGR1_19374776_ChIP-ChIP_THP-1_Human3.03786479
9FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.99904234
10SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.76202549
11* POU3F2_20337985_ChIP-ChIP_501MEL_Human2.65937060
12EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.62153477
13MYB_21317192_ChIP-Seq_ERMYB_Mouse2.61887270
14SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.59941937
15RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.56677848
16IRF8_21731497_ChIP-ChIP_J774_Mouse2.47900760
17MYB_26560356_Chip-Seq_TH2_Human2.44843620
18MYC_22102868_ChIP-Seq_BL_Human2.39898296
19* FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.27622899
20STAT4_19710469_ChIP-ChIP_TH1__Mouse2.26670657
21* TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.24977092
22ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.19885414
23CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.17147669
24ELF1_17652178_ChIP-ChIP_JURKAT_Human2.14300777
25IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.13522537
26RUNX_20019798_ChIP-Seq_JUKART_Human2.10617048
27SMAD_19615063_ChIP-ChIP_OVARY_Human2.08826632
28MAF_26560356_Chip-Seq_TH1_Human2.07355280
29VDR_21846776_ChIP-Seq_THP-1_Human2.06313885
30* SPI1_23547873_ChIP-Seq_NB4_Human2.05649199
31VDR_22108803_ChIP-Seq_LS180_Human2.03695765
32MYB_26560356_Chip-Seq_TH1_Human2.02231163
33STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.01747370
34FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.99668361
35FLI1_27457419_Chip-Seq_LIVER_Mouse1.98863256
36* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.93279976
37E2F4_17652178_ChIP-ChIP_JURKAT_Human1.92662777
38* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.89118806
39FUS_26573619_Chip-Seq_HEK293_Human1.87997472
40SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.87738160
41IGF1R_20145208_ChIP-Seq_DFB_Human1.87188813
42NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.86399315
43TAF15_26573619_Chip-Seq_HEK293_Human1.86074862
44IRF8_27001747_Chip-Seq_BMDM_Mouse1.83248030
45FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.77060093
46HOXB4_20404135_ChIP-ChIP_EML_Mouse1.76890384
47VDR_23849224_ChIP-Seq_CD4+_Human1.74826799
48LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.74162714
49VDR_24763502_ChIP-Seq_THP-1_Human1.74027446
50* RUNX1_22412390_ChIP-Seq_EML_Mouse1.73829902
51GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.69254672
52UTX_26944678_Chip-Seq_JUKART_Human1.68595901
53BRD4_27068464_Chip-Seq_AML-cells_Mouse1.68490597
54CIITA_25753668_ChIP-Seq_RAJI_Human1.67778679
55GATA3_27048872_Chip-Seq_THYMUS_Human1.67561166
56MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.66351907
57FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.64486659
58EWS_26573619_Chip-Seq_HEK293_Human1.63612628
59FOXM1_23109430_ChIP-Seq_U2OS_Human1.59907276
60RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.59765901
61PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.59485382
62GATA2_22383799_ChIP-Seq_G1ME_Mouse1.58886385
63TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.57656089
64E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.57225418
65Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.56138868
66GATA1_22383799_ChIP-Seq_G1ME_Mouse1.53819086
67LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.52754765
68GABP_17652178_ChIP-ChIP_JURKAT_Human1.49536630
69EZH2_27294783_Chip-Seq_NPCs_Mouse1.49356527
70ZFP57_27257070_Chip-Seq_ESCs_Mouse1.49289407
71NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.46671640
72* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.45530501
73ELK1_19687146_ChIP-ChIP_HELA_Human1.43870833
74SPI1_23127762_ChIP-Seq_K562_Human1.42533157
75FOXP3_21729870_ChIP-Seq_TREG_Human1.40296246
76TCF7_22412390_ChIP-Seq_EML_Mouse1.40253604
77NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.40012647
78NOTCH1_21737748_ChIP-Seq_TLL_Human1.38883011
79ER_23166858_ChIP-Seq_MCF-7_Human1.36697267
80PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.36600129
81CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.36503120
82FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.35862309
83GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.34766192
84PCGF2_27294783_Chip-Seq_ESCs_Mouse1.30369778
85E2F1_21310950_ChIP-Seq_MCF-7_Human1.28757207
86GATA3_26560356_Chip-Seq_TH2_Human1.28374797
87EST1_17652178_ChIP-ChIP_JURKAT_Human1.28108251
88CRX_20693478_ChIP-Seq_RETINA_Mouse1.27739699
89FLI1_21867929_ChIP-Seq_TH2_Mouse1.26393705
90SALL1_21062744_ChIP-ChIP_HESCs_Human1.26331460
91MAF_26560356_Chip-Seq_TH2_Human1.25065777
92AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.24634033
93SUZ12_27294783_Chip-Seq_NPCs_Mouse1.24419494
94OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.22898699
95CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.21208940
96PU_27001747_Chip-Seq_BMDM_Mouse1.19829102
97GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17656189
98P300_19829295_ChIP-Seq_ESCs_Human1.17380960
99* SALL4_22934838_ChIP-ChIP_CD34+_Human1.17126414
100SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.16751275
101ETS1_20019798_ChIP-Seq_JURKAT_Human1.16332200
102MYC_18555785_ChIP-Seq_MESCs_Mouse1.16089960
103MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.16082557
104NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.16065673
105OCT4_21477851_ChIP-Seq_ESCs_Mouse1.15978320
106VDR_24787735_ChIP-Seq_THP-1_Human1.15712939
107NANOG_18555785_Chip-Seq_ESCs_Mouse1.15620499
108NFE2_27457419_Chip-Seq_LIVER_Mouse1.15587606
109SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.15328570
110GBX2_23144817_ChIP-Seq_PC3_Human1.15238520
111FOXA1_21572438_ChIP-Seq_LNCaP_Human1.14308078
112GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.14216668
113ZNF274_21170338_ChIP-Seq_K562_Hela1.13559819
114GATA2_21666600_ChIP-Seq_HMVEC_Human1.13420528
115KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.12723363
116BP1_19119308_ChIP-ChIP_Hs578T_Human1.12546474
117TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.11255756
118GATA1_19941827_ChIP-Seq_MEL_Mouse1.09800500
119SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.09605464
120RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.08838328
121P53_22387025_ChIP-Seq_ESCs_Mouse1.06688730
122MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.06611305
123IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.05753465
124CBP_20019798_ChIP-Seq_JUKART_Human1.05753465
125SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.05556848
126EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.04765622
127HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.04423869
128TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.03501404
129PRDM14_20953172_ChIP-Seq_ESCs_Human1.03404233
130E2F1_18555785_Chip-Seq_ESCs_Mouse1.03222331
131GABP_19822575_ChIP-Seq_HepG2_Human1.03021847
132UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.02053961
133ETS1_22383799_ChIP-Seq_G1ME_Mouse1.01086440
134CMYC_18555785_Chip-Seq_ESCs_Mouse1.00089002
135SUZ12_18555785_Chip-Seq_ESCs_Mouse0.99898950
136NANOG_19829295_ChIP-Seq_ESCs_Human0.98766712
137SOX2_19829295_ChIP-Seq_ESCs_Human0.98766712
138GATA1_19941826_ChIP-Seq_K562_Human0.98558281
139CREB1_15753290_ChIP-ChIP_HEK293T_Human0.97987250
140EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.97690150
141KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.97511656
142KDM5A_27292631_Chip-Seq_BREAST_Human0.97127123
143MYC_18358816_ChIP-ChIP_MESCs_Mouse0.96162251
144TFEB_21752829_ChIP-Seq_HELA_Human0.96131066
145KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.96042991
146DCP1A_22483619_ChIP-Seq_HELA_Human0.95962391
147CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.95953803
148* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.94924166
149TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.94705022
150FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.94337573
151SRF_21415370_ChIP-Seq_HL-1_Mouse0.91950656
152PU.1_20513432_ChIP-Seq_Bcells_Mouse0.91269126
153TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.90708551
154JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.88364991
155* ZFX_18555785_ChIP-Seq_MESCs_Mouse0.88231927
156STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.86292867
157* KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.85513204
158PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.85496277
159XRN2_22483619_ChIP-Seq_HELA_Human0.84882470
160CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.84655972

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation3.43954694
2MP0002166_altered_tumor_susceptibility3.31416837
3MP0004510_myositis3.13564533
4MP0005671_abnormal_response_to3.09221138
5MP0003763_abnormal_thymus_physiology2.91548120
6MP0002396_abnormal_hematopoietic_system2.82384612
7MP0000685_abnormal_immune_system2.73286626
8MP0002006_tumorigenesis2.59060929
9MP0004808_abnormal_hematopoietic_stem2.58366488
10MP0008057_abnormal_DNA_replication2.51979520
11MP0001800_abnormal_humoral_immune2.49469072
12MP0002398_abnormal_bone_marrow2.37846983
13MP0006054_spinal_hemorrhage2.37650816
14MP0005397_hematopoietic_system_phenotyp2.29507009
15MP0001545_abnormal_hematopoietic_system2.29507009
16MP0009785_altered_susceptibility_to2.24725597
17MP0003656_abnormal_erythrocyte_physiolo2.22755324
18MP0002420_abnormal_adaptive_immunity2.22148070
19MP0005464_abnormal_platelet_physiology2.21585170
20MP0001819_abnormal_immune_cell2.18548025
21MP0003300_gastrointestinal_ulcer2.15325451
22MP0002452_abnormal_antigen_presenting2.14306036
23MP0005000_abnormal_immune_tolerance2.13583286
24MP0002723_abnormal_immune_serum2.11373362
25MP0001790_abnormal_immune_system2.07804055
26MP0005387_immune_system_phenotype2.07804055
27MP0003787_abnormal_imprinting2.07261435
28MP0003724_increased_susceptibility_to2.05907490
29MP0000569_abnormal_digit_pigmentation2.05752178
30MP0000716_abnormal_immune_system1.99538422
31MP0005025_abnormal_response_to1.98166985
32MP0005174_abnormal_tail_pigmentation1.94425563
33MP0000689_abnormal_spleen_morphology1.91424743
34MP0003436_decreased_susceptibility_to1.89244500
35MP0002722_abnormal_immune_system1.86599706
36MP0004147_increased_porphyrin_level1.82559743
37MP0000703_abnormal_thymus_morphology1.80067816
38MP0002429_abnormal_blood_cell1.78440126
39MP0005075_abnormal_melanosome_morpholog1.77235464
40MP0001873_stomach_inflammation1.76229507
41MP0002419_abnormal_innate_immunity1.75773455
42MP0002877_abnormal_melanocyte_morpholog1.70817571
43MP0010155_abnormal_intestine_physiology1.70532125
44MP0009333_abnormal_splenocyte_physiolog1.65575730
45MP0002148_abnormal_hypersensitivity_rea1.64566718
46MP0000465_gastrointestinal_hemorrhage1.60559093
47MP0002405_respiratory_system_inflammati1.59035446
48MP0001845_abnormal_inflammatory_respons1.56487934
49MP0001853_heart_inflammation1.52677195
50MP0003866_abnormal_defecation1.51810386
51MP0003828_pulmonary_edema1.50131550
52MP0004947_skin_inflammation1.49553099
53MP0004484_altered_response_of1.46024245
54MP0002095_abnormal_skin_pigmentation1.41823623
55MP0003693_abnormal_embryo_hatching1.40335390
56MP0000490_abnormal_crypts_of1.39945175
57MP0003172_abnormal_lysosome_physiology1.35690211
58MP0000015_abnormal_ear_pigmentation1.35508875
59MP0000749_muscle_degeneration1.34154785
60MP0003303_peritoneal_inflammation1.33373720
61MP0002102_abnormal_ear_morphology1.32470329
62MP0005310_abnormal_salivary_gland1.22529921
63MP0005058_abnormal_lysosome_morphology1.21148777
64MP0003806_abnormal_nucleotide_metabolis1.20442407
65MP0005084_abnormal_gallbladder_morpholo1.18920832
66MP0000372_irregular_coat_pigmentation1.18897349
67MP0002933_joint_inflammation1.18265326
68MP0000858_altered_metastatic_potential1.17982672
69MP0002009_preneoplasia1.15844594
70MP0001851_eye_inflammation1.12556347
71MP0003279_aneurysm1.12522082
72MP0008469_abnormal_protein_level1.10883303
73MP0003183_abnormal_peptide_metabolism1.10366414
74MP0010094_abnormal_chromosome_stability1.09027019
75MP0006036_abnormal_mitochondrial_physio1.03075840
76MP0002019_abnormal_tumor_incidence1.02522518
77MP0009278_abnormal_bone_marrow1.02311920
78MP0001533_abnormal_skeleton_physiology0.99869425
79MP0002928_abnormal_bile_duct0.99278852
80MP0008877_abnormal_DNA_methylation0.97715018
81MP0009697_abnormal_copulation0.94480963
82MP0003123_paternal_imprinting0.93375111
83MP0008007_abnormal_cellular_replicative0.92535528
84MP0006082_CNS_inflammation0.89525636
85MP0008058_abnormal_DNA_repair0.87919702
86MP0000343_altered_response_to0.86650564
87MP0001501_abnormal_sleep_pattern0.86555746
88MP0000371_diluted_coat_color0.84911844
89MP0004957_abnormal_blastocyst_morpholog0.83166515
90MP0008872_abnormal_physiological_respon0.82590905
91MP0003786_premature_aging0.81391094
92MP0008260_abnormal_autophagy0.80799561
93MP0001986_abnormal_taste_sensitivity0.80335596
94MP0004215_abnormal_myocardial_fiber0.79997626
95MP0000013_abnormal_adipose_tissue0.78878011
96MP0003880_abnormal_central_pattern0.77738039
97MP0000230_abnormal_systemic_arterial0.77513717
98MP0010307_abnormal_tumor_latency0.77494586
99MP0005535_abnormal_body_temperature0.77158819
100MP0002693_abnormal_pancreas_physiology0.76855237
101MP0003943_abnormal_hepatobiliary_system0.75870714
102MP0005646_abnormal_pituitary_gland0.74998215
103MP0004381_abnormal_hair_follicle0.74747594
104MP0008995_early_reproductive_senescence0.74451086
105MP0001663_abnormal_digestive_system0.73058501
106MP0001919_abnormal_reproductive_system0.72760343
107MP0004130_abnormal_muscle_cell0.70923716
108MP0006035_abnormal_mitochondrial_morpho0.69252957
109MP0009764_decreased_sensitivity_to0.68548906
110MP0003186_abnormal_redox_activity0.66916119
111MP0005379_endocrine/exocrine_gland_phen0.65212643
112MP0009763_increased_sensitivity_to0.64281591
113MP0003950_abnormal_plasma_membrane0.63530315
114MP0002837_dystrophic_cardiac_calcinosis0.63190811
115MP0004883_abnormal_blood_vessel0.62412255
116MP0003191_abnormal_cellular_cholesterol0.61629174
117MP0009765_abnormal_xenobiotic_induced0.61443489
118MP0005166_decreased_susceptibility_to0.61011041
119MP0003448_altered_tumor_morphology0.60982398
120MP0003075_altered_response_to0.60801750
121MP0003077_abnormal_cell_cycle0.60052321
122MP0001765_abnormal_ion_homeostasis0.59364838
123MP0000681_abnormal_thyroid_gland0.59172222
124MP0000249_abnormal_blood_vessel0.59034188
125MP0003252_abnormal_bile_duct0.57998713
126MP0005220_abnormal_exocrine_pancreas0.57121059
127MP0006292_abnormal_olfactory_placode0.57098518
128MP0002138_abnormal_hepatobiliary_system0.53854013
129MP0000598_abnormal_liver_morphology0.53638436
130MP0005636_abnormal_mineral_homeostasis0.52917436
131MP0000313_abnormal_cell_death0.52832369
132MP0008873_increased_physiological_sensi0.51826011

Predicted human phenotypes

RankGene SetZ-score
1Chronic otitis media (HP:0000389)4.31917193
2Stomatitis (HP:0010280)4.31272178
3T lymphocytopenia (HP:0005403)4.21171752
4Abnormality of T cell number (HP:0011839)4.08498939
5Recurrent bronchitis (HP:0002837)3.99700363
6IgM deficiency (HP:0002850)3.90502724
7Recurrent abscess formation (HP:0002722)3.90484466
8Recurrent viral infections (HP:0004429)3.81847376
9Recurrent bacterial skin infections (HP:0005406)3.78838534
10Abnormality of T cells (HP:0002843)3.62481198
11Abnormal delayed hypersensitivity skin test (HP:0002963)3.62334054
12Nasal polyposis (HP:0100582)3.61289401
13Thrombocytosis (HP:0001894)3.47583793
14Abnormality of the nasal mucosa (HP:0000433)3.43218855
15Elevated erythrocyte sedimentation rate (HP:0003565)3.43213211
16Panhypogammaglobulinemia (HP:0003139)3.37674117
17Myositis (HP:0100614)3.33275968
18Thyroiditis (HP:0100646)3.27611914
19Abnormality of B cell number (HP:0010975)3.26629864
20B lymphocytopenia (HP:0010976)3.26629864
21Petechiae (HP:0000967)3.26386998
22Decreased central vision (HP:0007663)3.24982155
23Limb-girdle muscle atrophy (HP:0003797)3.23318695
24Recurrent fungal infections (HP:0002841)3.13825022
25Severe combined immunodeficiency (HP:0004430)3.13139082
26Abnormality of T cell physiology (HP:0011840)3.10062697
27Hypochromic microcytic anemia (HP:0004840)2.96523911
28Prolonged bleeding time (HP:0003010)2.95079199
29Aplastic anemia (HP:0001915)2.93503993
30Absent rod-and cone-mediated responses on ERG (HP:0007688)2.88271181
31Abnormality of the prostate (HP:0008775)2.86539956
32Meningitis (HP:0001287)2.85887652
33Metaphyseal dysplasia (HP:0100255)2.85228133
34Chronic sinusitis (HP:0011109)2.84955041
35Abnormality of the hip-girdle musculature (HP:0001445)2.84732578
36Abnormality of the musculature of the pelvis (HP:0001469)2.84732578
37Combined immunodeficiency (HP:0005387)2.77677737
38Bronchitis (HP:0012387)2.76364189
39Periodontitis (HP:0000704)2.74486320
40Hypoplasia of the thymus (HP:0000778)2.73717878
41Inflammation of the large intestine (HP:0002037)2.72889537
42Abnormal number of erythroid precursors (HP:0012131)2.72299316
43Focal motor seizures (HP:0011153)2.72159474
44Abnormality of the heme biosynthetic pathway (HP:0010472)2.71814098
45Gastrointestinal inflammation (HP:0004386)2.71759411
46Verrucae (HP:0200043)2.66965969
47Papilloma (HP:0012740)2.66965969
48Agammaglobulinemia (HP:0004432)2.66354549
49Cellulitis (HP:0100658)2.65066021
50Granulocytopenia (HP:0001913)2.61171097
51Renal cortical cysts (HP:0000803)2.60213751
52Eosinophilia (HP:0001880)2.59764467
53Encephalitis (HP:0002383)2.58354227
54Spontaneous hematomas (HP:0007420)2.57719250
55Epistaxis (HP:0000421)2.57526559
56Abnormality of cells of the erythroid lineage (HP:0012130)2.57203622
57Abnormality of eosinophils (HP:0001879)2.57042464
58Eczematoid dermatitis (HP:0000976)2.56630337
59IgG deficiency (HP:0004315)2.56534034
60Papilledema (HP:0001085)2.53952156
61Stomach cancer (HP:0012126)2.52987382
62Abnormality of the vasculature of the conjunctiva (HP:0008054)2.52722732
63Acute hepatic failure (HP:0006554)2.51827496
64Impaired platelet aggregation (HP:0003540)2.49798466
65Abnormal platelet function (HP:0011869)2.49798466
66Dyschromatopsia (HP:0007641)2.46494159
67Lymphopenia (HP:0001888)2.44861837
68Recurrent skin infections (HP:0001581)2.42885782
69Hematochezia (HP:0002573)2.39966811
70Acute myeloid leukemia (HP:0004808)2.38882552
71Chest pain (HP:0100749)2.38356173
72Gastrointestinal infarctions (HP:0005244)2.36090398
73Abnormality of cells of the lymphoid lineage (HP:0012140)2.35480793
74Abnormality of the fingertips (HP:0001211)2.34063346
75Leukocytosis (HP:0001974)2.30899702
76Visual hallucinations (HP:0002367)2.30838235
77Gingival bleeding (HP:0000225)2.30217140
78Abnormality of aspartate family amino acid metabolism (HP:0010899)2.29945472
79Keratoconjunctivitis (HP:0001096)2.28290037
80Pulmonary infiltrates (HP:0002113)2.26070463
81Febrile seizures (HP:0002373)2.25841656
82Microcytic anemia (HP:0001935)2.24496474
83Mediastinal lymphadenopathy (HP:0100721)2.22132441
84Vasculitis (HP:0002633)2.21935740
85Alveolar cell carcinoma (HP:0006519)2.21535835
86Abnormal rod and cone electroretinograms (HP:0008323)2.18272933
87Neoplasm of the tracheobronchial system (HP:0100552)2.18020593
88Lymphoma (HP:0002665)2.14701349
89Albinism (HP:0001022)2.13337731
90Abnormal platelet volume (HP:0011876)2.12844996
91Abnormality of the renal cortex (HP:0011035)2.12189422
92Gastrointestinal stroma tumor (HP:0100723)2.12101662
93Papillary thyroid carcinoma (HP:0002895)2.11426504
94Colitis (HP:0002583)2.08562777
95Cone-rod dystrophy (HP:0000548)2.05176827
96Vacuolated lymphocytes (HP:0001922)2.04393642
97IgA deficiency (HP:0002720)2.02905850
98Recurrent sinusitis (HP:0011108)2.02511036
99Pustule (HP:0200039)2.01982522
100Recurrent cutaneous fungal infections (HP:0011370)2.01925976
101Chronic mucocutaneous candidiasis (HP:0002728)2.01925976
102Autoimmune hemolytic anemia (HP:0001890)1.99920293
103Osteomyelitis (HP:0002754)1.99180965
104Neurodegeneration (HP:0002180)1.97638626
105Orchitis (HP:0100796)1.97411687
106Absent frontal sinuses (HP:0002688)1.96855463
107Thyroid carcinoma (HP:0002890)1.96524015
1083-Methylglutaconic aciduria (HP:0003535)1.95627446
109Increased IgE level (HP:0003212)1.94697358
110Decreased electroretinogram (ERG) amplitude (HP:0000654)1.94665514
111Volvulus (HP:0002580)1.93810201
112Myelodysplasia (HP:0002863)1.91196558
113Keratoconjunctivitis sicca (HP:0001097)1.89879258
114Acanthocytosis (HP:0001927)1.89420536
115Retrobulbar optic neuritis (HP:0100654)1.88164079
116Optic neuritis (HP:0100653)1.88164079
117Acute lymphatic leukemia (HP:0006721)1.87621527
118Pulmonary embolism (HP:0002204)1.85562289
119Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.85391773
120Atonic seizures (HP:0010819)1.84732951
121Joint swelling (HP:0001386)1.84551641
122Vertigo (HP:0002321)1.83768942
12311 pairs of ribs (HP:0000878)1.83172839
124Autoimmune thrombocytopenia (HP:0001973)1.82121936
125Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.82084701
126Abnormality of lateral ventricle (HP:0030047)1.81498518
127Constricted visual fields (HP:0001133)1.81106892
128Erythema (HP:0010783)1.80387259
129Abnormality of iron homeostasis (HP:0011031)1.79701071
130Abnormality of the left ventricular outflow tract (HP:0011103)1.78843729
131Subaortic stenosis (HP:0001682)1.78843729
132Poikilocytosis (HP:0004447)1.78540629
133Exertional dyspnea (HP:0002875)1.78441083
134Hemoptysis (HP:0002105)1.77315290
135Arterial thrombosis (HP:0004420)1.76165758
136Fatigue (HP:0012378)1.75709665
137Neutropenia (HP:0001875)1.75705402
138Chronic diarrhea (HP:0002028)1.75539423
139Skin ulcer (HP:0200042)1.74807431
140Hypochromic anemia (HP:0001931)1.72864089
141Obstructive lung disease (HP:0006536)1.70912223
142Chronic obstructive pulmonary disease (HP:0006510)1.70912223
143Bronchiectasis (HP:0002110)1.69647045

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K14.01656522
2TXK2.92152654
3STK162.81667543
4CAMKK22.75248568
5BRSK22.64929570
6BMPR22.40484007
7TEC2.37720886
8MAP4K22.32424950
9ZAP702.31513730
10RIPK42.21532461
11BTK2.16859382
12NUAK11.95176023
13MAP3K121.93703437
14SYK1.88369623
15SCYL21.87180734
16FLT31.84502400
17KIT1.84189876
18TAOK31.82547573
19MST41.81465071
20NME21.79096928
21JAK31.74620112
22ITK1.65798418
23GRK61.64299334
24MAP3K131.63254652
25EEF2K1.54318822
26TBK11.53365690
27JAK11.50016722
28TYK21.47748509
29CCNB11.46181767
30BUB11.44788351
31IKBKE1.44656587
32STK101.42383382
33LRRK21.38451862
34ACVR1B1.37917689
35ERN11.37294738
36BRSK11.35283190
37PLK21.34191322
38RPS6KA41.27483290
39TRIB31.22630752
40PKN21.18882136
41CDC71.15848416
42CSF1R1.15274755
43IRAK41.15135888
44MAP2K31.13120659
45ERBB31.11113091
46FES1.10959180
47TNK21.10536255
48CDK41.10414075
49MKNK11.10060317
50EIF2AK11.05755585
51PDK10.99893763
52BLK0.99793264
53PBK0.99474456
54TAF10.99152025
55BCKDK0.98313772
56DAPK10.95115324
57LCK0.94495828
58MAP2K60.92950112
59CAMKK10.90387418
60TGFBR20.89002418
61LYN0.87493436
62HCK0.87412411
63MATK0.87373424
64RAF10.87194284
65IKBKB0.86547333
66EIF2AK30.86243177
67MAP3K140.85821670
68GRK50.83777007
69PIM10.83587113
70NLK0.83555078
71PIM20.81325129
72MAPKAPK30.81188551
73CLK10.80980049
74DAPK20.80479830
75PINK10.79673471
76STK40.79254599
77BMPR1B0.77549941
78CSK0.77159975
79JAK20.76294129
80NEK20.75257863
81MAPK110.75164550
82FGFR30.74967743
83EIF2AK20.74910901
84OXSR10.73345804
85KDR0.72638943
86NEK90.71777047
87IRAK10.68944572
88MAP3K100.68737482
89MUSK0.67947656
90MAP3K80.67652877
91VRK10.67644550
92CDK60.67605880
93PTK2B0.67547191
94AKT30.66511163
95MARK30.64524777
96MAPK40.63840273
97HIPK20.62552220
98PLK30.62380064
99CDK90.61418308
100MAP3K60.60272420
101MKNK20.59919570
102PRKCQ0.59741575
103MAPK70.58254864
104STK240.57357835
105FRK0.57239459
106ZAK0.55959302
107PRKG20.55100577
108ATR0.54677655
109PDPK10.54665834
110TAOK20.54559470
111SGK20.53821496
112MYLK0.50478111
113PDK30.50208180
114PDK40.50208180
115TRPM70.49229849
116TGFBR10.46803097
117FGR0.46734901
118ADRBK20.45298327
119BRD40.45241018
120STK30.44296450
121MAP3K40.43637639
122MAP3K30.43230166
123DYRK1A0.42706831
124MAP3K110.42091770
125RPS6KB20.42035610
126CDK190.41256916
127MAP3K10.40690625
128FGFR20.40398804
129MAP3K50.40385466
130ABL10.40257639
131PIK3CG0.39315007
132CDK70.39186650
133MINK10.38875904
134MAPKAPK50.37878844
135TNIK0.37515042
136RPS6KB10.37355204
137YES10.36728248
138FER0.35555563
139PASK0.35222520
140PRKCH0.34647822
141MAP2K40.34588754
142STK390.34305464
143MAP3K70.33488308

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053404.16217037
2DNA replication_Homo sapiens_hsa030302.85808219
3Asthma_Homo sapiens_hsa053102.74246527
4Autoimmune thyroid disease_Homo sapiens_hsa053202.67588978
5Antigen processing and presentation_Homo sapiens_hsa046122.46035828
6B cell receptor signaling pathway_Homo sapiens_hsa046622.39509150
7Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.18654987
8Hematopoietic cell lineage_Homo sapiens_hsa046402.15409393
9Protein export_Homo sapiens_hsa030602.03545108
10Ribosome_Homo sapiens_hsa030101.99225282
11T cell receptor signaling pathway_Homo sapiens_hsa046601.90342999
12Measles_Homo sapiens_hsa051621.87657171
13Leishmaniasis_Homo sapiens_hsa051401.84686531
14Osteoclast differentiation_Homo sapiens_hsa043801.77243455
15NF-kappa B signaling pathway_Homo sapiens_hsa040641.63204035
16RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.61376313
17Intestinal immune network for IgA production_Homo sapiens_hsa046721.60539510
18SNARE interactions in vesicular transport_Homo sapiens_hsa041301.59172781
19Staphylococcus aureus infection_Homo sapiens_hsa051501.53626942
20Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.52654411
21Mismatch repair_Homo sapiens_hsa034301.51080264
22Caffeine metabolism_Homo sapiens_hsa002321.50604510
23Shigellosis_Homo sapiens_hsa051311.47607093
24Platelet activation_Homo sapiens_hsa046111.46750543
25Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.45604021
26Herpes simplex infection_Homo sapiens_hsa051681.45125054
27Jak-STAT signaling pathway_Homo sapiens_hsa046301.42857297
28Rheumatoid arthritis_Homo sapiens_hsa053231.42497631
29Regulation of autophagy_Homo sapiens_hsa041401.42144613
30Acute myeloid leukemia_Homo sapiens_hsa052211.40155459
31Base excision repair_Homo sapiens_hsa034101.39852616
32Non-homologous end-joining_Homo sapiens_hsa034501.36084700
33Viral myocarditis_Homo sapiens_hsa054161.31993758
34Hepatitis B_Homo sapiens_hsa051611.28468843
35Legionellosis_Homo sapiens_hsa051341.27320149
36Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.24213963
37Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.21531867
38Toll-like receptor signaling pathway_Homo sapiens_hsa046201.21040628
39NOD-like receptor signaling pathway_Homo sapiens_hsa046211.20902745
40Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.19725591
41Renin secretion_Homo sapiens_hsa049241.18818566
42Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.18036561
43Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.17639607
44Influenza A_Homo sapiens_hsa051641.12945827
45N-Glycan biosynthesis_Homo sapiens_hsa005101.12729988
46Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.11791617
47Toxoplasmosis_Homo sapiens_hsa051451.10891417
48Dorso-ventral axis formation_Homo sapiens_hsa043201.09077818
49Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.08908078
50Viral carcinogenesis_Homo sapiens_hsa052031.08859958
51Phototransduction_Homo sapiens_hsa047441.08592176
52Homologous recombination_Homo sapiens_hsa034401.03915841
53Cell cycle_Homo sapiens_hsa041101.03671482
54Thyroid cancer_Homo sapiens_hsa052161.03366604
55Tuberculosis_Homo sapiens_hsa051521.03256971
56African trypanosomiasis_Homo sapiens_hsa051431.01375903
57Chemokine signaling pathway_Homo sapiens_hsa040621.00683716
58Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.99208095
59Systemic lupus erythematosus_Homo sapiens_hsa053220.98206341
60Other glycan degradation_Homo sapiens_hsa005110.96548270
61Long-term potentiation_Homo sapiens_hsa047200.96022521
62Olfactory transduction_Homo sapiens_hsa047400.95470331
63Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.93656021
64Leukocyte transendothelial migration_Homo sapiens_hsa046700.92821170
65Apoptosis_Homo sapiens_hsa042100.92078919
66Allograft rejection_Homo sapiens_hsa053300.89506558
67Pertussis_Homo sapiens_hsa051330.88843930
68Salivary secretion_Homo sapiens_hsa049700.88818920
69Non-small cell lung cancer_Homo sapiens_hsa052230.88688672
70RNA degradation_Homo sapiens_hsa030180.88372001
71Neurotrophin signaling pathway_Homo sapiens_hsa047220.87637263
72Chronic myeloid leukemia_Homo sapiens_hsa052200.87022576
73Pentose phosphate pathway_Homo sapiens_hsa000300.79681517
74Long-term depression_Homo sapiens_hsa047300.78628934
75Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.76274694
76Epstein-Barr virus infection_Homo sapiens_hsa051690.76272126
77Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.76243774
78Transcriptional misregulation in cancer_Homo sapiens_hsa052020.75513409
79Pancreatic secretion_Homo sapiens_hsa049720.74735072
80Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.72505624
81TNF signaling pathway_Homo sapiens_hsa046680.72197635
82Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.71193668
83Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.70347867
84Taste transduction_Homo sapiens_hsa047420.69635781
85Spliceosome_Homo sapiens_hsa030400.68430779
86Pancreatic cancer_Homo sapiens_hsa052120.67819929
87Nucleotide excision repair_Homo sapiens_hsa034200.66761129
88HTLV-I infection_Homo sapiens_hsa051660.66704425
89Carbohydrate digestion and absorption_Homo sapiens_hsa049730.65816291
90Collecting duct acid secretion_Homo sapiens_hsa049660.65483544
91Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.64479118
92Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.63407497
93p53 signaling pathway_Homo sapiens_hsa041150.63119870
94Amphetamine addiction_Homo sapiens_hsa050310.62456551
95Oxytocin signaling pathway_Homo sapiens_hsa049210.61492828
96Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.60982499
97Serotonergic synapse_Homo sapiens_hsa047260.59987584
98Adipocytokine signaling pathway_Homo sapiens_hsa049200.59250602
99Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.58438454
100Circadian entrainment_Homo sapiens_hsa047130.57674018
101Pyrimidine metabolism_Homo sapiens_hsa002400.55572886
102Proteasome_Homo sapiens_hsa030500.55566325
103Propanoate metabolism_Homo sapiens_hsa006400.54646191
104Nitrogen metabolism_Homo sapiens_hsa009100.54389003
105VEGF signaling pathway_Homo sapiens_hsa043700.54265527
106Insulin resistance_Homo sapiens_hsa049310.53338795
107Basal transcription factors_Homo sapiens_hsa030220.53021950
108Vascular smooth muscle contraction_Homo sapiens_hsa042700.51924022
109Type I diabetes mellitus_Homo sapiens_hsa049400.51902744
110Sphingolipid signaling pathway_Homo sapiens_hsa040710.51880250
111Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.50954252
112cGMP-PKG signaling pathway_Homo sapiens_hsa040220.50525299
113Graft-versus-host disease_Homo sapiens_hsa053320.49975299
114Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.49838090
115Hepatitis C_Homo sapiens_hsa051600.49471576
116Salmonella infection_Homo sapiens_hsa051320.47929135
117AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.46059601
118mTOR signaling pathway_Homo sapiens_hsa041500.45040938
119Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.44476518
120Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.44090245
121Ether lipid metabolism_Homo sapiens_hsa005650.44060018
122FoxO signaling pathway_Homo sapiens_hsa040680.43343886
123Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.43103860
124Arachidonic acid metabolism_Homo sapiens_hsa005900.42936127
125RNA transport_Homo sapiens_hsa030130.42825957
126Circadian rhythm_Homo sapiens_hsa047100.42653514
127Fanconi anemia pathway_Homo sapiens_hsa034600.41732142
128alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.41006511
129Prolactin signaling pathway_Homo sapiens_hsa049170.40177011
130Glucagon signaling pathway_Homo sapiens_hsa049220.39546013
131Small cell lung cancer_Homo sapiens_hsa052220.38861497
132Malaria_Homo sapiens_hsa051440.38787416
133Phosphatidylinositol signaling system_Homo sapiens_hsa040700.38621110
134Glycosaminoglycan degradation_Homo sapiens_hsa005310.38542328
135Inositol phosphate metabolism_Homo sapiens_hsa005620.38443196
136Phagosome_Homo sapiens_hsa041450.37845421
137Morphine addiction_Homo sapiens_hsa050320.37733080
138Oocyte meiosis_Homo sapiens_hsa041140.37445809
139Renin-angiotensin system_Homo sapiens_hsa046140.36103540
140Purine metabolism_Homo sapiens_hsa002300.35274608

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