Rank | Gene Set | Z-score |
---|---|---|
1 | endocardial cushion morphogenesis (GO:0003203) | 6.83177238 |
2 | regulation of somitogenesis (GO:0014807) | 6.25186756 |
3 | heart valve formation (GO:0003188) | 6.12716937 |
4 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 5.88756871 |
5 | Notch signaling involved in heart development (GO:0061314) | 5.49379599 |
6 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 5.37033136 |
7 | desmosome organization (GO:0002934) | 5.36357950 |
8 | axon extension involved in axon guidance (GO:0048846) | 5.22691840 |
9 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 5.22691840 |
10 | midgut development (GO:0007494) | 5.12214101 |
11 | collecting duct development (GO:0072044) | 5.12213311 |
12 | neuronal stem cell maintenance (GO:0097150) | 4.92101539 |
13 | mesenchyme morphogenesis (GO:0072132) | 4.89247681 |
14 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 4.86220043 |
15 | somite development (GO:0061053) | 4.79671676 |
16 | establishment of skin barrier (GO:0061436) | 4.74862497 |
17 | mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337) | 4.67263616 |
18 | atrioventricular valve morphogenesis (GO:0003181) | 4.66340489 |
19 | cellular response to cholesterol (GO:0071397) | 4.65024447 |
20 | positive regulation of astrocyte differentiation (GO:0048711) | 4.65000380 |
21 | regulation of extracellular matrix organization (GO:1903053) | 4.59227500 |
22 | coronary vasculature morphogenesis (GO:0060977) | 4.46589569 |
23 | cell migration involved in heart development (GO:0060973) | 4.32609946 |
24 | venous blood vessel morphogenesis (GO:0048845) | 4.32126777 |
25 | ventricular trabecula myocardium morphogenesis (GO:0003222) | 4.27551071 |
26 | * lung epithelium development (GO:0060428) | 4.27513446 |
27 | regulation of water loss via skin (GO:0033561) | 4.26528454 |
28 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 4.25552059 |
29 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 4.25263027 |
30 | cellular response to follicle-stimulating hormone stimulus (GO:0071372) | 4.18285085 |
31 | regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768) | 4.16773783 |
32 | heart trabecula morphogenesis (GO:0061384) | 4.09105574 |
33 | nephron tubule development (GO:0072080) | 4.09103734 |
34 | regulation of endothelial cell chemotaxis (GO:2001026) | 4.07240084 |
35 | regulation of cholesterol homeostasis (GO:2000188) | 4.07191732 |
36 | exocrine pancreas development (GO:0031017) | 4.02434877 |
37 | cardiac left ventricle morphogenesis (GO:0003214) | 3.97086916 |
38 | * lens fiber cell development (GO:0070307) | 3.94768941 |
39 | cellular response to sterol (GO:0036315) | 3.91986021 |
40 | very-low-density lipoprotein particle assembly (GO:0034379) | 3.86361074 |
41 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 3.84768225 |
42 | plasma lipoprotein particle assembly (GO:0034377) | 3.82672037 |
43 | regulation of cholesterol biosynthetic process (GO:0045540) | 3.80481072 |
44 | proline metabolic process (GO:0006560) | 3.77166175 |
45 | multicellular organismal water homeostasis (GO:0050891) | 3.76759802 |
46 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.75913433 |
47 | renal system development (GO:0072001) | 3.75816969 |
48 | positive regulation of synapse maturation (GO:0090129) | 3.73451376 |
49 | * regulation of astrocyte differentiation (GO:0048710) | 3.69571309 |
50 | negative regulation of fibrinolysis (GO:0051918) | 3.65316508 |
51 | protein carboxylation (GO:0018214) | 3.64800153 |
52 | peptidyl-glutamic acid carboxylation (GO:0017187) | 3.64800153 |
53 | positive regulation of extracellular matrix organization (GO:1903055) | 3.58308506 |
54 | renal tubule development (GO:0061326) | 3.55499293 |
55 | regulation of cholesterol esterification (GO:0010872) | 3.50975334 |
56 | keratinization (GO:0031424) | 3.49589924 |
57 | protein-lipid complex assembly (GO:0065005) | 3.48296230 |
58 | * negative regulation of astrocyte differentiation (GO:0048712) | 3.45408598 |
59 | negative regulation of glial cell proliferation (GO:0060253) | 3.45230589 |
60 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.41400439 |
61 | * negative regulation of glial cell differentiation (GO:0045686) | 3.41078236 |
62 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 3.37661094 |
63 | somatic stem cell division (GO:0048103) | 3.36827171 |
64 | * epithelial cell fate commitment (GO:0072148) | 3.36651741 |
65 | thalamus development (GO:0021794) | 3.35980319 |
66 | embryonic camera-type eye development (GO:0031076) | 3.35569568 |
67 | notochord development (GO:0030903) | 3.30473702 |
68 | positive regulation of neuroblast proliferation (GO:0002052) | 3.25192789 |
69 | dorsal/ventral neural tube patterning (GO:0021904) | 3.24643855 |
70 | cardiac muscle cell proliferation (GO:0060038) | 3.22667020 |
71 | embryonic viscerocranium morphogenesis (GO:0048703) | 3.22539035 |
72 | intestinal cholesterol absorption (GO:0030299) | 3.22004319 |
73 | regulation of synapse maturation (GO:0090128) | 3.21972060 |
74 | glutamate secretion (GO:0014047) | 3.21898341 |
75 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.21825979 |
76 | plasma lipoprotein particle remodeling (GO:0034369) | 3.21728857 |
77 | protein-lipid complex remodeling (GO:0034368) | 3.21728857 |
78 | macromolecular complex remodeling (GO:0034367) | 3.21728857 |
79 | cell-cell junction maintenance (GO:0045217) | 3.21603765 |
80 | type B pancreatic cell development (GO:0003323) | 3.21268395 |
81 | negative regulation of sterol transport (GO:0032372) | 3.20761311 |
82 | negative regulation of cholesterol transport (GO:0032375) | 3.20761311 |
83 | high-density lipoprotein particle remodeling (GO:0034375) | 3.19993641 |
84 | alanine transport (GO:0032328) | 3.19778162 |
85 | nephron epithelium development (GO:0072009) | 3.18970049 |
86 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.18624693 |
87 | trabecula morphogenesis (GO:0061383) | 3.18291919 |
88 | myoblast migration (GO:0051451) | 3.17539555 |
89 | negative regulation of osteoblast proliferation (GO:0033689) | 3.17363691 |
90 | lateral sprouting from an epithelium (GO:0060601) | 3.16675350 |
91 | regulation of bile acid biosynthetic process (GO:0070857) | 3.16613226 |
92 | low-density lipoprotein particle remodeling (GO:0034374) | 3.13869977 |
93 | negative regulation of chondrocyte differentiation (GO:0032331) | 3.11793665 |
94 | regulation of fibrinolysis (GO:0051917) | 3.11325496 |
95 | glutamate metabolic process (GO:0006536) | 3.11022873 |
96 | regulation of branching involved in prostate gland morphogenesis (GO:0060687) | 3.09463625 |
97 | proline biosynthetic process (GO:0006561) | 3.08438423 |
98 | regulation of apoptotic cell clearance (GO:2000425) | 3.05552900 |
99 | left/right axis specification (GO:0070986) | 3.05288880 |
100 | water homeostasis (GO:0030104) | 3.05127191 |
101 | cerebellar granule cell differentiation (GO:0021707) | 3.05048156 |
102 | cell surface receptor signaling pathway involved in heart development (GO:0061311) | 3.04729864 |
103 | layer formation in cerebral cortex (GO:0021819) | 3.03769791 |
104 | reverse cholesterol transport (GO:0043691) | 2.99759033 |
105 | locomotory exploration behavior (GO:0035641) | 2.99538612 |
106 | embryonic retina morphogenesis in camera-type eye (GO:0060059) | 2.99429304 |
107 | heart valve morphogenesis (GO:0003179) | 2.99422265 |
108 | alpha-linolenic acid metabolic process (GO:0036109) | 2.98860668 |
109 | sodium ion homeostasis (GO:0055078) | 2.98273566 |
110 | L-amino acid import (GO:0043092) | 2.97369718 |
111 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.96931926 |
112 | cardiac epithelial to mesenchymal transition (GO:0060317) | 2.95840510 |
113 | regulation of protein activation cascade (GO:2000257) | 2.94777263 |
114 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 2.92752296 |
115 | plasma lipoprotein particle organization (GO:0071827) | 2.92002351 |
116 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 2.91870095 |
117 | cholesterol efflux (GO:0033344) | 2.91840047 |
118 | negative regulation of myoblast differentiation (GO:0045662) | 2.90687595 |
119 | * axon ensheathment in central nervous system (GO:0032291) | 2.90516075 |
120 | * central nervous system myelination (GO:0022010) | 2.90516075 |
121 | keratinocyte proliferation (GO:0043616) | 2.90448913 |
122 | limb bud formation (GO:0060174) | 2.88614137 |
123 | phospholipid efflux (GO:0033700) | 2.88140149 |
124 | regulation of complement activation (GO:0030449) | 2.86996186 |
125 | lung-associated mesenchyme development (GO:0060484) | 2.86411134 |
126 | barbed-end actin filament capping (GO:0051016) | 2.84288761 |
127 | positive regulation of branching involved in ureteric bud morphogenesis (GO:0090190) | 2.83537543 |
128 | striated muscle cell proliferation (GO:0014855) | 2.83400325 |
129 | mammary gland epithelial cell differentiation (GO:0060644) | 2.82171752 |
130 | protein-lipid complex subunit organization (GO:0071825) | 2.78747044 |
131 | potassium ion homeostasis (GO:0055075) | 2.78240459 |
132 | Notch receptor processing (GO:0007220) | 2.77446785 |
133 | response to follicle-stimulating hormone (GO:0032354) | 2.74737468 |
134 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 2.74482450 |
135 | sodium ion export (GO:0071436) | 2.73465901 |
136 | negative regulation of catenin import into nucleus (GO:0035414) | 2.72790522 |
137 | regulation of cholesterol metabolic process (GO:0090181) | 2.72304121 |
138 | respiratory tube development (GO:0030323) | 2.72194274 |
139 | negative regulation of myotube differentiation (GO:0010832) | 2.71922532 |
140 | * negative regulation of smoothened signaling pathway (GO:0045879) | 2.71731841 |
141 | regulation of transcription from RNA polymerase II promoter involved in heart development (GO:190121 | 2.69815748 |
142 | renal system process involved in regulation of systemic arterial blood pressure (GO:0003071) | 2.69209808 |
143 | gamma-aminobutyric acid transport (GO:0015812) | 2.67927963 |
144 | response to muramyl dipeptide (GO:0032495) | 2.67819294 |
145 | amino acid import (GO:0043090) | 2.67512776 |
146 | neuroblast proliferation (GO:0007405) | 2.67428818 |
147 | muscle cell fate commitment (GO:0042693) | 2.66276888 |
148 | positive regulation of steroid metabolic process (GO:0045940) | 2.65668886 |
149 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 2.65142258 |
150 | endothelial cell differentiation (GO:0045446) | 2.62811245 |
151 | response to cholesterol (GO:0070723) | 2.62680333 |
152 | cochlea morphogenesis (GO:0090103) | 2.61787211 |
153 | glutamine family amino acid biosynthetic process (GO:0009084) | 2.60904839 |
154 | astrocyte differentiation (GO:0048708) | 2.60799669 |
155 | cell junction maintenance (GO:0034331) | 2.60726897 |
156 | cellular potassium ion homeostasis (GO:0030007) | 2.60641122 |
157 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 2.60363489 |
158 | ventricular septum morphogenesis (GO:0060412) | 2.59488923 |
159 | establishment of planar polarity (GO:0001736) | 2.59303353 |
160 | establishment of tissue polarity (GO:0007164) | 2.59303353 |
161 | regulation of oligodendrocyte differentiation (GO:0048713) | 2.59231870 |
162 | nephron tubule morphogenesis (GO:0072078) | 2.58673917 |
163 | nephron epithelium morphogenesis (GO:0072088) | 2.58673917 |
164 | negative regulation of lipase activity (GO:0060192) | 2.58640002 |
165 | hair follicle morphogenesis (GO:0031069) | 2.57509740 |
166 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 2.56528167 |
167 | cellular sodium ion homeostasis (GO:0006883) | 2.56523149 |
168 | C4-dicarboxylate transport (GO:0015740) | 2.55926190 |
169 | muscle cell proliferation (GO:0033002) | 2.55748666 |
170 | regulation of neuronal synaptic plasticity (GO:0048168) | 2.54040801 |
171 | dicarboxylic acid biosynthetic process (GO:0043650) | 2.52670317 |
172 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 2.51629734 |
173 | L-phenylalanine catabolic process (GO:0006559) | 2.51629734 |
174 | positive regulation of dendritic spine development (GO:0060999) | 2.50900240 |
175 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 2.50433530 |
176 | G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:0007199 | 2.48987577 |
177 | regulation of establishment of planar polarity (GO:0090175) | 2.48950486 |
178 | one-carbon compound transport (GO:0019755) | 2.48350131 |
179 | apical protein localization (GO:0045176) | 2.47038672 |
180 | regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081) | 2.46706230 |
181 | synaptic vesicle maturation (GO:0016188) | 2.45342346 |
182 | vocalization behavior (GO:0071625) | 2.44484492 |
183 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 2.43375790 |
184 | L-phenylalanine metabolic process (GO:0006558) | 2.43375790 |
185 | neurotransmitter secretion (GO:0007269) | 2.43126590 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 5.02014029 |
2 | * EZH2_18974828_ChIP-Seq_MESCs_Mouse | 3.05055821 |
3 | * RNF2_18974828_ChIP-Seq_MESCs_Mouse | 3.05055821 |
4 | * SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 3.01372914 |
5 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.89887019 |
6 | * EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.75330116 |
7 | * SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.72298320 |
8 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.69591960 |
9 | * SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.61017915 |
10 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.60092985 |
11 | * JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.58647253 |
12 | * JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.55088197 |
13 | * SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.54118533 |
14 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.51902254 |
15 | * SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.45375015 |
16 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.30155229 |
17 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.28901191 |
18 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.25001072 |
19 | * RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.24234020 |
20 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.19855267 |
21 | * EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.16470175 |
22 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.15906518 |
23 | * SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.13568173 |
24 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 2.11587390 |
25 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.02062619 |
26 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.00422229 |
27 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.92359339 |
28 | * PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.92160599 |
29 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.83871330 |
30 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.82361120 |
31 | * RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.81408830 |
32 | * CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.73195905 |
33 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.72812160 |
34 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.71367220 |
35 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.70899670 |
36 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.69167442 |
37 | * EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.68930986 |
38 | * TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.59824358 |
39 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.58943321 |
40 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.58890305 |
41 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.51488527 |
42 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.48987285 |
43 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.46487949 |
44 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.44955764 |
45 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.43184566 |
46 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.43121465 |
47 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.41677163 |
48 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.38398502 |
49 | * WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.35436705 |
50 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.35002921 |
51 | * CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.34855971 |
52 | * RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.33007820 |
53 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.31670948 |
54 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.30844798 |
55 | P68_20966046_ChIP-Seq_HELA_Human | 1.28704432 |
56 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.28524734 |
57 | * SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.27961153 |
58 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.26738650 |
59 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.25834477 |
60 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.25257302 |
61 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.25134618 |
62 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.24514773 |
63 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.24012253 |
64 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.22851831 |
65 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.22279791 |
66 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.22186513 |
67 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.21386806 |
68 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.19987363 |
69 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.19387262 |
70 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 1.17450357 |
71 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.15894746 |
72 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.15407935 |
73 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.15107741 |
74 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.13594897 |
75 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.13570926 |
76 | * TP63_22573176_ChIP-Seq_HFKS_Human | 1.11910719 |
77 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.10607900 |
78 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.09558436 |
79 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.09521866 |
80 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.09463328 |
81 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.09044437 |
82 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.08360996 |
83 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.07818405 |
84 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.07327602 |
85 | * KDM2B_26808549_Chip-Seq_K562_Human | 1.06967467 |
86 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.06480722 |
87 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.04490076 |
88 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.04437999 |
89 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.04407112 |
90 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.04242627 |
91 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.04036157 |
92 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.03248581 |
93 | * KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.03213693 |
94 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.02252746 |
95 | * PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.02232144 |
96 | RXR_22108803_ChIP-Seq_LS180_Human | 0.99707669 |
97 | GATA3_20176728_ChIP-ChIP_TSCs_Mouse | 0.97767784 |
98 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.97628042 |
99 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.96674793 |
100 | * DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.96171133 |
101 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.95642864 |
102 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 0.95273221 |
103 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.94826329 |
104 | * HNF4A_19822575_ChIP-Seq_HepG2_Human | 0.94655268 |
105 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.94319412 |
106 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.94016103 |
107 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.93952823 |
108 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.93737125 |
109 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.93249365 |
110 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.92837507 |
111 | TP53_16413492_ChIP-PET_HCT116_Human | 0.92830530 |
112 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 0.92255395 |
113 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.92016929 |
114 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.91843988 |
115 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.91784767 |
116 | AR_25329375_ChIP-Seq_VCAP_Human | 0.91699006 |
117 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.91288582 |
118 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.91250264 |
119 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.90976395 |
120 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.89532641 |
121 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.89429324 |
122 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.89094839 |
123 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.88344066 |
124 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.85336610 |
125 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.84471170 |
126 | AR_19668381_ChIP-Seq_PC3_Human | 0.82604506 |
127 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.82220072 |
128 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.81655190 |
129 | * OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.81282274 |
130 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.79694441 |
131 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.78940065 |
132 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.77106438 |
133 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.75747328 |
134 | * EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.74591922 |
135 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.72789771 |
136 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.71860487 |
137 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.71533545 |
138 | P300_19829295_ChIP-Seq_ESCs_Human | 0.71340929 |
139 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.70808326 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003880_abnormal_central_pattern | 7.33022822 |
2 | MP0005423_abnormal_somatic_nervous | 7.01693513 |
3 | MP0010030_abnormal_orbit_morphology | 5.71091503 |
4 | MP0002249_abnormal_larynx_morphology | 3.15790358 |
5 | MP0003122_maternal_imprinting | 2.88331369 |
6 | MP0004381_abnormal_hair_follicle | 2.64126673 |
7 | * MP0000566_synostosis | 2.56119740 |
8 | MP0002102_abnormal_ear_morphology | 2.49075139 |
9 | MP0003283_abnormal_digestive_organ | 2.44444505 |
10 | MP0003941_abnormal_skin_development | 2.43544368 |
11 | MP0005257_abnormal_intraocular_pressure | 2.36112837 |
12 | MP0004859_abnormal_synaptic_plasticity | 2.32375736 |
13 | MP0009379_abnormal_foot_pigmentation | 2.23331559 |
14 | MP0005409_darkened_coat_color | 2.14241916 |
15 | MP0003136_yellow_coat_color | 2.05236763 |
16 | MP0006276_abnormal_autonomic_nervous | 2.03427921 |
17 | MP0003183_abnormal_peptide_metabolism | 1.93821911 |
18 | MP0004264_abnormal_extraembryonic_tissu | 1.93023022 |
19 | MP0000762_abnormal_tongue_morphology | 1.92265029 |
20 | MP0000647_abnormal_sebaceous_gland | 1.90926934 |
21 | MP0000579_abnormal_nail_morphology | 1.88569964 |
22 | MP0002139_abnormal_hepatobiliary_system | 1.88096800 |
23 | MP0005501_abnormal_skin_physiology | 1.82540829 |
24 | MP0003705_abnormal_hypodermis_morpholog | 1.82046668 |
25 | MP0002098_abnormal_vibrissa_morphology | 1.81936882 |
26 | MP0001666_abnormal_nutrient_absorption | 1.80716360 |
27 | MP0000778_abnormal_nervous_system | 1.74821295 |
28 | MP0005646_abnormal_pituitary_gland | 1.70985009 |
29 | MP0000537_abnormal_urethra_morphology | 1.66336410 |
30 | MP0003938_abnormal_ear_development | 1.65843514 |
31 | MP0004885_abnormal_endolymph | 1.58799523 |
32 | MP0003123_paternal_imprinting | 1.58783442 |
33 | MP0004858_abnormal_nervous_system | 1.54170537 |
34 | MP0001486_abnormal_startle_reflex | 1.53320566 |
35 | MP0005360_urolithiasis | 1.52245561 |
36 | MP0003878_abnormal_ear_physiology | 1.50667505 |
37 | MP0005377_hearing/vestibular/ear_phenot | 1.50667505 |
38 | MP0003635_abnormal_synaptic_transmissio | 1.48783357 |
39 | MP0001346_abnormal_lacrimal_gland | 1.47214598 |
40 | MP0003329_amyloid_beta_deposits | 1.47086288 |
41 | MP0002282_abnormal_trachea_morphology | 1.44794881 |
42 | * MP0000049_abnormal_middle_ear | 1.40160990 |
43 | MP0009250_abnormal_appendicular_skeleto | 1.38545966 |
44 | MP0009384_cardiac_valve_regurgitation | 1.34058011 |
45 | MP0002254_reproductive_system_inflammat | 1.32531551 |
46 | * MP0000026_abnormal_inner_ear | 1.31055660 |
47 | MP0003690_abnormal_glial_cell | 1.26622651 |
48 | MP0000462_abnormal_digestive_system | 1.24478150 |
49 | MP0005248_abnormal_Harderian_gland | 1.23952125 |
50 | MP0000467_abnormal_esophagus_morphology | 1.23325920 |
51 | MP0000955_abnormal_spinal_cord | 1.22316113 |
52 | MP0005365_abnormal_bile_salt | 1.21326093 |
53 | MP0005076_abnormal_cell_differentiation | 1.19935251 |
54 | * MP0009780_abnormal_chondrocyte_physiolo | 1.19063317 |
55 | MP0009672_abnormal_birth_weight | 1.16823902 |
56 | MP0001188_hyperpigmentation | 1.16124061 |
57 | * MP0000163_abnormal_cartilage_morphology | 1.15928696 |
58 | MP0001216_abnormal_epidermal_layer | 1.14976848 |
59 | MP0002234_abnormal_pharynx_morphology | 1.13169545 |
60 | MP0005275_abnormal_skin_tensile | 1.12199993 |
61 | MP0002063_abnormal_learning/memory/cond | 1.09385523 |
62 | MP0001485_abnormal_pinna_reflex | 1.09052860 |
63 | MP0002064_seizures | 1.07632630 |
64 | MP0000383_abnormal_hair_follicle | 1.05725908 |
65 | MP0005085_abnormal_gallbladder_physiolo | 1.03387772 |
66 | * MP0002089_abnormal_postnatal_growth/wei | 1.02591757 |
67 | MP0002751_abnormal_autonomic_nervous | 1.02102384 |
68 | MP0003634_abnormal_glial_cell | 1.01870507 |
69 | MP0002233_abnormal_nose_morphology | 1.01322781 |
70 | MP0010771_integument_phenotype | 1.00485857 |
71 | MP0001984_abnormal_olfaction | 0.98828523 |
72 | MP0000534_abnormal_ureter_morphology | 0.98279962 |
73 | MP0001293_anophthalmia | 0.98246297 |
74 | MP0009745_abnormal_behavioral_response | 0.98072552 |
75 | MP0010678_abnormal_skin_adnexa | 0.97994738 |
76 | MP0002734_abnormal_mechanical_nocicepti | 0.97794618 |
77 | MP0005332_abnormal_amino_acid | 0.97636956 |
78 | MP0004270_analgesia | 0.95580691 |
79 | MP0009053_abnormal_anal_canal | 0.92521714 |
80 | MP0003632_abnormal_nervous_system | 0.92098028 |
81 | MP0003119_abnormal_digestive_system | 0.91933926 |
82 | MP0003861_abnormal_nervous_system | 0.91901285 |
83 | MP0004043_abnormal_pH_regulation | 0.91759937 |
84 | * MP0000428_abnormal_craniofacial_morphol | 0.91533744 |
85 | MP0003942_abnormal_urinary_system | 0.91165793 |
86 | MP0002092_abnormal_eye_morphology | 0.87830112 |
87 | MP0008961_abnormal_basal_metabolism | 0.87729863 |
88 | MP0002697_abnormal_eye_size | 0.85693710 |
89 | MP0003937_abnormal_limbs/digits/tail_de | 0.84181821 |
90 | MP0000678_abnormal_parathyroid_gland | 0.82424074 |
91 | MP0002572_abnormal_emotion/affect_behav | 0.82230817 |
92 | MP0002796_impaired_skin_barrier | 0.81761682 |
93 | MP0008875_abnormal_xenobiotic_pharmacok | 0.79848506 |
94 | MP0003879_abnormal_hair_cell | 0.79339785 |
95 | MP0005220_abnormal_exocrine_pancreas | 0.78809158 |
96 | MP0000920_abnormal_myelination | 0.77559463 |
97 | * MP0003755_abnormal_palate_morphology | 0.77448188 |
98 | MP0004782_abnormal_surfactant_physiolog | 0.77175444 |
99 | * MP0002882_abnormal_neuron_morphology | 0.76708693 |
100 | MP0001440_abnormal_grooming_behavior | 0.76472178 |
101 | MP0004133_heterotaxia | 0.75007632 |
102 | * MP0001963_abnormal_hearing_physiology | 0.74989226 |
103 | MP0003315_abnormal_perineum_morphology | 0.74957621 |
104 | MP0010329_abnormal_lipoprotein_level | 0.74294029 |
105 | MP0003385_abnormal_body_wall | 0.74011638 |
106 | MP0001340_abnormal_eyelid_morphology | 0.72767811 |
107 | MP0004233_abnormal_muscle_weight | 0.72691477 |
108 | MP0004742_abnormal_vestibular_system | 0.72689936 |
109 | * MP0001299_abnormal_eye_distance/ | 0.72409460 |
110 | MP0001849_ear_inflammation | 0.72251495 |
111 | * MP0002111_abnormal_tail_morphology | 0.71789176 |
112 | MP0001286_abnormal_eye_development | 0.70822407 |
113 | * MP0002115_abnormal_skeleton_extremities | 0.70722122 |
114 | MP0009046_muscle_twitch | 0.70714418 |
115 | MP0000377_abnormal_hair_follicle | 0.69786607 |
116 | * MP0003115_abnormal_respiratory_system | 0.68525683 |
117 | MP0003453_abnormal_keratinocyte_physiol | 0.67976322 |
118 | MP0004019_abnormal_vitamin_homeostasis | 0.67694933 |
119 | MP0003631_nervous_system_phenotype | 0.67619358 |
120 | MP0000639_abnormal_adrenal_gland | 0.67388349 |
121 | MP0005623_abnormal_meninges_morphology | 0.67103026 |
122 | MP0004185_abnormal_adipocyte_glucose | 0.66738145 |
123 | MP0002152_abnormal_brain_morphology | 0.66731454 |
124 | MP0001270_distended_abdomen | 0.66142704 |
125 | MP0003890_abnormal_embryonic-extraembry | 0.66087974 |
126 | MP0002557_abnormal_social/conspecific_i | 0.65141027 |
127 | MP0002653_abnormal_ependyma_morphology | 0.63994809 |
128 | MP0003075_altered_response_to | 0.63506741 |
129 | MP0001177_atelectasis | 0.62851832 |
130 | MP0003137_abnormal_impulse_conducting | 0.62126382 |
131 | MP0001502_abnormal_circadian_rhythm | 0.62060018 |
132 | MP0000604_amyloidosis | 0.60845962 |
133 | MP0002067_abnormal_sensory_capabilities | 0.60806747 |
134 | MP0003252_abnormal_bile_duct | 0.60773411 |
135 | MP0002932_abnormal_joint_morphology | 0.58953000 |
136 | MP0003633_abnormal_nervous_system | 0.58157751 |
137 | MP0004883_abnormal_blood_vessel | 0.57325494 |
138 | * MP0002116_abnormal_craniofacial_bone | 0.57127425 |
139 | MP0010234_abnormal_vibrissa_follicle | 0.56833692 |
140 | MP0002822_catalepsy | 0.55125529 |
141 | MP0002272_abnormal_nervous_system | 0.54486670 |
142 | * MP0008569_lethality_at_weaning | 0.54277993 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Adactyly (HP:0009776) | 5.77323191 |
2 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 4.86563335 |
3 | Aplasia cutis congenita (HP:0001057) | 4.47213579 |
4 | Epiphyseal dysplasia (HP:0002656) | 4.12543260 |
5 | Synostosis involving the elbow (HP:0003938) | 4.09677778 |
6 | Humeroradial synostosis (HP:0003041) | 4.09677778 |
7 | * Aplasia involving bones of the extremities (HP:0009825) | 3.90383923 |
8 | * Aplasia involving bones of the upper limbs (HP:0009823) | 3.90383923 |
9 | * Aplasia of the phalanges of the hand (HP:0009802) | 3.90383923 |
10 | Abnormality of the right ventricle (HP:0001707) | 3.79156547 |
11 | Arterial tortuosity (HP:0005116) | 3.63982297 |
12 | * Neonatal short-limb short stature (HP:0008921) | 3.62723094 |
13 | Skull defect (HP:0001362) | 3.39199580 |
14 | * Mixed hearing impairment (HP:0000410) | 3.21068990 |
15 | Neurofibrillary tangles (HP:0002185) | 3.18672080 |
16 | Split foot (HP:0001839) | 3.13294812 |
17 | Vascular tortuosity (HP:0004948) | 3.12730605 |
18 | Esophageal varix (HP:0002040) | 3.12477869 |
19 | Bronchomalacia (HP:0002780) | 3.06515159 |
20 | Hypoplastic ischia (HP:0003175) | 2.95592597 |
21 | Prolonged partial thromboplastin time (HP:0003645) | 2.95129101 |
22 | Absent toe (HP:0010760) | 2.90815696 |
23 | Abnormality of the pubic bones (HP:0003172) | 2.83931569 |
24 | * Osteoarthritis (HP:0002758) | 2.83275197 |
25 | Abnormal vertebral ossification (HP:0100569) | 2.78771668 |
26 | Hypotrichosis (HP:0001006) | 2.77619322 |
27 | Joint hemorrhage (HP:0005261) | 2.71960354 |
28 | * Megalencephaly (HP:0001355) | 2.69808834 |
29 | Abnormality of the ischium (HP:0003174) | 2.63182133 |
30 | Absent hand (HP:0004050) | 2.62932795 |
31 | Exostoses (HP:0100777) | 2.62821394 |
32 | Broad alveolar ridges (HP:0000187) | 2.61672084 |
33 | Complement deficiency (HP:0004431) | 2.57907895 |
34 | Vitreoretinal degeneration (HP:0000655) | 2.57593754 |
35 | Ulnar bowing (HP:0003031) | 2.56014355 |
36 | Choanal stenosis (HP:0000452) | 2.53202606 |
37 | Hypercholesterolemia (HP:0003124) | 2.48788387 |
38 | Hypobetalipoproteinemia (HP:0003563) | 2.46850234 |
39 | * Bifid scrotum (HP:0000048) | 2.45382915 |
40 | Delayed CNS myelination (HP:0002188) | 2.45033307 |
41 | Cerebral inclusion bodies (HP:0100314) | 2.41960211 |
42 | Palmoplantar hyperkeratosis (HP:0000972) | 2.40913265 |
43 | Hemorrhage of the eye (HP:0011885) | 2.39758321 |
44 | Alopecia of scalp (HP:0002293) | 2.39194243 |
45 | * Abnormality of the salivary glands (HP:0010286) | 2.37996864 |
46 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 2.36168152 |
47 | Oligodactyly (HP:0012165) | 2.35492279 |
48 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.34648652 |
49 | Obstructive sleep apnea (HP:0002870) | 2.31913426 |
50 | Right ventricular cardiomyopathy (HP:0011663) | 2.31425826 |
51 | Supernumerary ribs (HP:0005815) | 2.28365623 |
52 | * Alacrima (HP:0000522) | 2.27306172 |
53 | Palmar hyperkeratosis (HP:0010765) | 2.25332351 |
54 | Irregular epiphyses (HP:0010582) | 2.23733673 |
55 | Absent eyelashes (HP:0000561) | 2.22815208 |
56 | * Abnormality of the middle phalanges of the toes (HP:0010183) | 2.21468945 |
57 | Cutaneous finger syndactyly (HP:0010554) | 2.21009341 |
58 | Focal motor seizures (HP:0011153) | 2.20688387 |
59 | Hemiplegia (HP:0002301) | 2.20187557 |
60 | Overriding aorta (HP:0002623) | 2.19583129 |
61 | Turricephaly (HP:0000262) | 2.18288068 |
62 | Myokymia (HP:0002411) | 2.15389948 |
63 | Shallow orbits (HP:0000586) | 2.14634898 |
64 | * Abnormality of the lacrimal duct (HP:0011481) | 2.12587011 |
65 | Bile duct proliferation (HP:0001408) | 2.12325760 |
66 | Abnormal biliary tract physiology (HP:0012439) | 2.12325760 |
67 | Cutaneous syndactyly (HP:0012725) | 2.12084551 |
68 | Spondylolisthesis (HP:0003302) | 2.11780345 |
69 | Woolly hair (HP:0002224) | 2.11683928 |
70 | Protrusio acetabuli (HP:0003179) | 2.10923212 |
71 | Hepatoblastoma (HP:0002884) | 2.10819653 |
72 | Plantar hyperkeratosis (HP:0007556) | 2.08986777 |
73 | Abnormal ossification of hand bones (HP:0005921) | 2.08979512 |
74 | Abnormality of the intervertebral disk (HP:0005108) | 2.08833823 |
75 | Advanced eruption of teeth (HP:0006288) | 2.08299753 |
76 | Oligodactyly (hands) (HP:0001180) | 2.05754566 |
77 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 2.02109296 |
78 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.01783500 |
79 | Abnormality of glycine metabolism (HP:0010895) | 2.01783500 |
80 | Hypoplastic labia majora (HP:0000059) | 2.00451286 |
81 | Flat acetabular roof (HP:0003180) | 2.00219945 |
82 | Abnormality of secondary sexual hair (HP:0009888) | 1.99821331 |
83 | Abnormality of the axillary hair (HP:0100134) | 1.99821331 |
84 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 1.99614491 |
85 | Tracheomalacia (HP:0002779) | 1.99323953 |
86 | * Coronal craniosynostosis (HP:0004440) | 1.98702760 |
87 | Bilateral microphthalmos (HP:0007633) | 1.98662503 |
88 | * Abnormality of permanent molar morphology (HP:0011071) | 1.98003991 |
89 | * Abnormality of the dental root (HP:0006486) | 1.98003991 |
90 | * Taurodontia (HP:0000679) | 1.98003991 |
91 | Broad face (HP:0000283) | 1.97832383 |
92 | Increased number of teeth (HP:0011069) | 1.97436390 |
93 | Abnormal hair laboratory examination (HP:0003328) | 1.96059116 |
94 | Broad palm (HP:0001169) | 1.95622652 |
95 | Pili torti (HP:0003777) | 1.95313255 |
96 | Esophageal atresia (HP:0002032) | 1.94093130 |
97 | Small epiphyses (HP:0010585) | 1.93963341 |
98 | Hypoplastic nipples (HP:0002557) | 1.93803288 |
99 | Spastic diplegia (HP:0001264) | 1.92319823 |
100 | Onycholysis (HP:0001806) | 1.91918634 |
101 | * Nasolacrimal duct obstruction (HP:0000579) | 1.91245997 |
102 | Abnormality of the nasal septum (HP:0000419) | 1.91166696 |
103 | * Partial duplication of thumb phalanx (HP:0009944) | 1.89716352 |
104 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.89691323 |
105 | Ankle clonus (HP:0011448) | 1.89670586 |
106 | Aplasia/Hypoplasia of the fibula (HP:0006492) | 1.89645464 |
107 | Concave nail (HP:0001598) | 1.88201433 |
108 | Fragile nails (HP:0001808) | 1.87932369 |
109 | Septate vagina (HP:0001153) | 1.87157987 |
110 | Broad distal phalanx of finger (HP:0009836) | 1.86865290 |
111 | Hyperlipoproteinemia (HP:0010980) | 1.86630668 |
112 | Skin pits (HP:0100276) | 1.86240944 |
113 | Trigonocephaly (HP:0000243) | 1.85863641 |
114 | Deep venous thrombosis (HP:0002625) | 1.85614210 |
115 | Abnormality of complement system (HP:0005339) | 1.85042629 |
116 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.84486002 |
117 | Hypoplastic pelvis (HP:0008839) | 1.83706938 |
118 | Cavernous hemangioma (HP:0001048) | 1.82822295 |
119 | Genetic anticipation (HP:0003743) | 1.82777135 |
120 | Renal duplication (HP:0000075) | 1.82770962 |
121 | Abnormality of carpal bone ossification (HP:0006257) | 1.82415335 |
122 | Abnormality of the parietal bone (HP:0002696) | 1.81961800 |
123 | Hyperacusis (HP:0010780) | 1.81060729 |
124 | Acanthocytosis (HP:0001927) | 1.80181734 |
125 | Abnormal hand bone ossification (HP:0010660) | 1.79772728 |
126 | Abnormality of nail color (HP:0100643) | 1.79252668 |
127 | Protuberant abdomen (HP:0001538) | 1.79231803 |
128 | Scanning speech (HP:0002168) | 1.78770182 |
129 | Long nose (HP:0003189) | 1.78634645 |
130 | Porencephaly (HP:0002132) | 1.78589750 |
131 | Progressive cerebellar ataxia (HP:0002073) | 1.78492092 |
132 | Pseudobulbar signs (HP:0002200) | 1.77818461 |
133 | Erythroderma (HP:0001019) | 1.77696098 |
134 | Bowel incontinence (HP:0002607) | 1.77454637 |
135 | Delayed epiphyseal ossification (HP:0002663) | 1.76587009 |
136 | * Abnormality of the dental pulp (HP:0006479) | 1.75737924 |
137 | Asymmetry of the thorax (HP:0001555) | 1.75606991 |
138 | Aortic aneurysm (HP:0004942) | 1.75531425 |
139 | * Abnormality of molar morphology (HP:0011070) | 1.74884684 |
140 | * Abnormality of molar (HP:0011077) | 1.74884684 |
141 | 11 pairs of ribs (HP:0000878) | 1.74844362 |
142 | Neoplasm of the heart (HP:0100544) | 1.74757323 |
143 | Anophthalmia (HP:0000528) | 1.74657095 |
144 | Xanthomatosis (HP:0000991) | 1.74474681 |
145 | * Corneal erosion (HP:0200020) | 1.74176044 |
146 | Laryngomalacia (HP:0001601) | 1.74123311 |
147 | Insomnia (HP:0100785) | 1.73769201 |
148 | Abnormality of the labia majora (HP:0012881) | 1.73485079 |
149 | Oligodontia (HP:0000677) | 1.72525953 |
150 | Midline defect of the nose (HP:0004122) | 1.72494432 |
151 | Dysdiadochokinesis (HP:0002075) | 1.71309176 |
152 | Short hallux (HP:0010109) | 1.70118166 |
153 | Glomerulonephritis (HP:0000099) | 1.69990933 |
154 | Congenital ichthyosiform erythroderma (HP:0007431) | 1.69923137 |
155 | Action tremor (HP:0002345) | 1.69354558 |
156 | Epileptic encephalopathy (HP:0200134) | 1.69349879 |
157 | Ankyloglossia (HP:0010296) | 1.68359062 |
158 | Down-sloping shoulders (HP:0200021) | 1.68121555 |
159 | Bicuspid aortic valve (HP:0001647) | 1.68102551 |
160 | Potter facies (HP:0002009) | 1.67359542 |
161 | Facial shape deformation (HP:0011334) | 1.67359542 |
162 | Hemiparesis (HP:0001269) | 1.65523189 |
163 | Hypoplastic toenails (HP:0001800) | 1.65478593 |
164 | Coxa vara (HP:0002812) | 1.65274187 |
165 | Hypoalphalipoproteinemia (HP:0003233) | 1.65126701 |
166 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 1.64885426 |
167 | Fibular aplasia (HP:0002990) | 1.64671693 |
168 | Flat capital femoral epiphysis (HP:0003370) | 1.64631960 |
169 | Aplasia/Hypoplasia of the clavicles (HP:0006710) | 1.63803346 |
170 | Anomalous pulmonary venous return (HP:0010772) | 1.63363746 |
171 | Striae distensae (HP:0001065) | 1.63067022 |
172 | * Aplasia/Hypoplasia involving the pelvis (HP:0009103) | 1.62507512 |
173 | Status epilepticus (HP:0002133) | 1.61497724 |
174 | Portal hypertension (HP:0001409) | 1.60410316 |
175 | * Abnormality of the antihelix (HP:0009738) | 1.60287542 |
176 | Fibular hypoplasia (HP:0003038) | 1.60063735 |
177 | Hyperglycinuria (HP:0003108) | 1.59365407 |
178 | Back pain (HP:0003418) | 1.58944860 |
179 | Hydroxyprolinuria (HP:0003080) | 1.58769067 |
180 | Abnormality of proline metabolism (HP:0010907) | 1.58769067 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 8.40495049 |
2 | DDR2 | 3.38508503 |
3 | EPHA4 | 3.37351656 |
4 | EEF2K | 2.97806334 |
5 | CDK8 | 2.84099723 |
6 | ICK | 2.61881893 |
7 | EPHA2 | 2.61378526 |
8 | SIK1 | 2.31550747 |
9 | MAP3K7 | 2.16710612 |
10 | NTRK2 | 2.14071916 |
11 | LMTK2 | 2.11679702 |
12 | EPHB2 | 2.09163517 |
13 | NTRK3 | 1.95986014 |
14 | MAPK15 | 1.93745277 |
15 | TNIK | 1.89854991 |
16 | CDK12 | 1.88187318 |
17 | PHKG2 | 1.84620146 |
18 | PHKG1 | 1.84620146 |
19 | TRIB3 | 1.77438813 |
20 | PRKD3 | 1.67820174 |
21 | UHMK1 | 1.58773884 |
22 | SMG1 | 1.58773870 |
23 | PRKCZ | 1.52316573 |
24 | MUSK | 1.49566894 |
25 | PNCK | 1.47994171 |
26 | RIPK1 | 1.47438617 |
27 | MST1R | 1.45022246 |
28 | ROCK2 | 1.44726837 |
29 | BCKDK | 1.42208188 |
30 | WNK4 | 1.41724210 |
31 | FGFR2 | 1.41213192 |
32 | PAK6 | 1.40638540 |
33 | ROCK1 | 1.39280539 |
34 | MARK2 | 1.32704331 |
35 | DAPK2 | 1.31177671 |
36 | MAPKAPK3 | 1.30567808 |
37 | KSR1 | 1.28404473 |
38 | MAP3K4 | 1.24373134 |
39 | LATS1 | 1.21600243 |
40 | MINK1 | 1.17561702 |
41 | SGK494 | 1.17335101 |
42 | SGK223 | 1.17335101 |
43 | CAMKK1 | 1.16092622 |
44 | CDK9 | 1.09898432 |
45 | MELK | 1.07589582 |
46 | NTRK1 | 1.04262951 |
47 | WNK1 | 1.04010085 |
48 | MARK1 | 1.01757320 |
49 | MAP3K9 | 1.01033014 |
50 | NEK6 | 0.98007741 |
51 | ERBB2 | 0.96136119 |
52 | PRPF4B | 0.92237628 |
53 | * FGFR3 | 0.89876575 |
54 | MET | 0.88606621 |
55 | MAP2K4 | 0.88427678 |
56 | STK38 | 0.87841429 |
57 | BMX | 0.87045892 |
58 | MAP3K6 | 0.85923023 |
59 | DYRK1B | 0.85443243 |
60 | CDK5 | 0.82642359 |
61 | MTOR | 0.82361346 |
62 | RET | 0.81698312 |
63 | TYRO3 | 0.78447122 |
64 | KSR2 | 0.75205143 |
65 | DMPK | 0.75025558 |
66 | MAP2K7 | 0.73232648 |
67 | SGK1 | 0.72226485 |
68 | MAPK10 | 0.71353306 |
69 | RPS6KB1 | 0.71156490 |
70 | SIK2 | 0.70214003 |
71 | CASK | 0.70151453 |
72 | MAPK13 | 0.69913197 |
73 | MAPK12 | 0.68491762 |
74 | BRSK1 | 0.67775969 |
75 | LATS2 | 0.67767829 |
76 | PKN2 | 0.67750215 |
77 | RPS6KB2 | 0.67238967 |
78 | AKT2 | 0.65656641 |
79 | SGK2 | 0.64817842 |
80 | PAK3 | 0.64687287 |
81 | PRKCG | 0.63653382 |
82 | DYRK1A | 0.63563269 |
83 | PTK2 | 0.63410852 |
84 | PTK2B | 0.62138551 |
85 | PDPK1 | 0.60724091 |
86 | MAPK9 | 0.59901774 |
87 | PTK6 | 0.58309916 |
88 | PRKG2 | 0.58306655 |
89 | STK39 | 0.57623462 |
90 | MAPKAPK5 | 0.55986705 |
91 | CSNK1E | 0.55877898 |
92 | PRKAA2 | 0.54668986 |
93 | MAP2K6 | 0.53558838 |
94 | OXSR1 | 0.53452371 |
95 | CAMK1D | 0.53194489 |
96 | PDGFRA | 0.52850467 |
97 | SGK3 | 0.52328056 |
98 | CDK15 | 0.52058130 |
99 | CDK18 | 0.51782339 |
100 | NEK2 | 0.51771429 |
101 | BCR | 0.51487054 |
102 | PAK4 | 0.51289162 |
103 | CDK3 | 0.51024011 |
104 | TAOK1 | 0.50583762 |
105 | RPS6KA2 | 0.49458050 |
106 | CDK19 | 0.48574938 |
107 | RPS6KA3 | 0.47419489 |
108 | CAMK1G | 0.45586588 |
109 | AKT3 | 0.44925508 |
110 | CDC42BPA | 0.44365649 |
111 | STK24 | 0.44104984 |
112 | WEE1 | 0.43744231 |
113 | ERBB4 | 0.43572236 |
114 | IRAK3 | 0.41060924 |
115 | CDK7 | 0.40470772 |
116 | GSK3B | 0.39701496 |
117 | PRKACG | 0.39472105 |
118 | NME1 | 0.39438553 |
119 | CDK11A | 0.39403333 |
120 | MAP2K2 | 0.39266399 |
121 | * FGFR1 | 0.38415866 |
122 | BRD4 | 0.38371093 |
123 | INSRR | 0.38271651 |
124 | PRKCA | 0.38106977 |
125 | CDK14 | 0.38007848 |
126 | PRKCH | 0.37787741 |
127 | MAP3K13 | 0.37073518 |
128 | CAMK2B | 0.36717965 |
129 | TLK1 | 0.36697025 |
130 | SRC | 0.36564118 |
131 | MAP3K2 | 0.35220550 |
132 | MAP3K10 | 0.33085291 |
133 | FER | 0.32962609 |
134 | FYN | 0.32903835 |
135 | ERN1 | 0.32632029 |
136 | PRKCB | 0.31085642 |
137 | CAMK2A | 0.30941959 |
138 | FGFR4 | 0.30582637 |
139 | STK11 | 0.30103683 |
140 | STK38L | 0.30042146 |
141 | TTK | 0.29593884 |
142 | PINK1 | 0.25848516 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nitrogen metabolism_Homo sapiens_hsa00910 | 5.46258435 |
2 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 2.88908116 |
3 | Basal cell carcinoma_Homo sapiens_hsa05217 | 2.69442033 |
4 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 2.58346659 |
5 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 2.45807404 |
6 | Notch signaling pathway_Homo sapiens_hsa04330 | 2.45228474 |
7 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 2.30916818 |
8 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 2.22226950 |
9 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 2.17300608 |
10 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.05271477 |
11 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.87162820 |
12 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.77724439 |
13 | Bile secretion_Homo sapiens_hsa04976 | 1.69435848 |
14 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.65592496 |
15 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.61117946 |
16 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.59474997 |
17 | Nicotine addiction_Homo sapiens_hsa05033 | 1.49718572 |
18 | Prion diseases_Homo sapiens_hsa05020 | 1.46369250 |
19 | Salivary secretion_Homo sapiens_hsa04970 | 1.40019285 |
20 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.35003280 |
21 | GABAergic synapse_Homo sapiens_hsa04727 | 1.33327978 |
22 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.30223052 |
23 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.28092986 |
24 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.26164110 |
25 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.25551561 |
26 | Olfactory transduction_Homo sapiens_hsa04740 | 1.23871654 |
27 | Circadian entrainment_Homo sapiens_hsa04713 | 1.22967475 |
28 | Melanogenesis_Homo sapiens_hsa04916 | 1.22503389 |
29 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.22034242 |
30 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.20617320 |
31 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.17779215 |
32 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.14446090 |
33 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.13462175 |
34 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.10944392 |
35 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.07156318 |
36 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.06569076 |
37 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.01529193 |
38 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.00616455 |
39 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.97815037 |
40 | Insulin secretion_Homo sapiens_hsa04911 | 0.94670298 |
41 | Axon guidance_Homo sapiens_hsa04360 | 0.94480473 |
42 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.92801421 |
43 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.92312327 |
44 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.90900427 |
45 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.90502773 |
46 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.90344149 |
47 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.89444913 |
48 | Glioma_Homo sapiens_hsa05214 | 0.87805053 |
49 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.87324024 |
50 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.87279610 |
51 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.86752654 |
52 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.86697218 |
53 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.83999717 |
54 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.83885533 |
55 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.83377817 |
56 | Gap junction_Homo sapiens_hsa04540 | 0.83105190 |
57 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.83061190 |
58 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.82261827 |
59 | Cocaine addiction_Homo sapiens_hsa05030 | 0.81839437 |
60 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.81589118 |
61 | * Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.78529266 |
62 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.78163423 |
63 | Renin secretion_Homo sapiens_hsa04924 | 0.77546030 |
64 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.76657756 |
65 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.76351393 |
66 | Peroxisome_Homo sapiens_hsa04146 | 0.76237625 |
67 | Morphine addiction_Homo sapiens_hsa05032 | 0.75823871 |
68 | Tight junction_Homo sapiens_hsa04530 | 0.75268692 |
69 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.74833593 |
70 | Lysine degradation_Homo sapiens_hsa00310 | 0.74685850 |
71 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.73522351 |
72 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.71541279 |
73 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.70475734 |
74 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.70266699 |
75 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.70052793 |
76 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.69740089 |
77 | Adherens junction_Homo sapiens_hsa04520 | 0.68636968 |
78 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.68438892 |
79 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.68098300 |
80 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.66820430 |
81 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.66477307 |
82 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.66135435 |
83 | Long-term potentiation_Homo sapiens_hsa04720 | 0.66110639 |
84 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.63802085 |
85 | Long-term depression_Homo sapiens_hsa04730 | 0.63316478 |
86 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.62640850 |
87 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.61868408 |
88 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.60680907 |
89 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.59323733 |
90 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.57714920 |
91 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.57210286 |
92 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.56557614 |
93 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.55116274 |
94 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.54119033 |
95 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.54020123 |
96 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.53797125 |
97 | Retinol metabolism_Homo sapiens_hsa00830 | 0.53547238 |
98 | Histidine metabolism_Homo sapiens_hsa00340 | 0.53298996 |
99 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.52947591 |
100 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.52733382 |
101 | Endometrial cancer_Homo sapiens_hsa05213 | 0.51491841 |
102 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.51034584 |
103 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.49554978 |
104 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.48300379 |
105 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.48153681 |
106 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.47307063 |
107 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.46519366 |
108 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.46237451 |
109 | * Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.46193244 |
110 | Taste transduction_Homo sapiens_hsa04742 | 0.46147201 |
111 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.45937319 |
112 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.43935319 |
113 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.43008525 |
114 | ABC transporters_Homo sapiens_hsa02010 | 0.42995347 |
115 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.42766154 |
116 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.42399320 |
117 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.42218246 |
118 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.41000510 |
119 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.40693794 |
120 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.40576862 |
121 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.39827077 |
122 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.37821959 |
123 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.37687243 |
124 | Mineral absorption_Homo sapiens_hsa04978 | 0.37052874 |
125 | Focal adhesion_Homo sapiens_hsa04510 | 0.36138939 |
126 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.36031674 |