FGL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.43294861
2L-phenylalanine catabolic process (GO:0006559)7.43294861
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.13190471
4L-phenylalanine metabolic process (GO:0006558)7.13190471
5aromatic amino acid family catabolic process (GO:0009074)6.71744740
6exogenous drug catabolic process (GO:0042738)6.64865513
7epoxygenase P450 pathway (GO:0019373)6.55533886
8triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.49099870
9omega-hydroxylase P450 pathway (GO:0097267)6.30517141
10indole-containing compound catabolic process (GO:0042436)6.13222352
11indolalkylamine catabolic process (GO:0046218)6.13222352
12tryptophan catabolic process (GO:0006569)6.13222352
13kynurenine metabolic process (GO:0070189)5.93633906
14high-density lipoprotein particle remodeling (GO:0034375)5.91478645
15negative regulation of fibrinolysis (GO:0051918)5.89508476
16bile acid biosynthetic process (GO:0006699)5.77972723
17tryptophan metabolic process (GO:0006568)5.75514379
18regulation of fibrinolysis (GO:0051917)5.66177102
19urea cycle (GO:0000050)5.64838624
20urea metabolic process (GO:0019627)5.64838624
21regulation of plasminogen activation (GO:0010755)5.64064428
22glyoxylate metabolic process (GO:0046487)5.63702067
23regulation of protein activation cascade (GO:2000257)5.57863745
24complement activation, alternative pathway (GO:0006957)5.57708906
25peptidyl-glutamic acid carboxylation (GO:0017187)5.57332485
26protein carboxylation (GO:0018214)5.57332485
27regulation of humoral immune response (GO:0002920)5.52521047
28alpha-linolenic acid metabolic process (GO:0036109)5.35446663
29regulation of cholesterol esterification (GO:0010872)5.31776884
30intestinal cholesterol absorption (GO:0030299)5.30691347
31sulfur amino acid catabolic process (GO:0000098)5.20567522
32nitrogen cycle metabolic process (GO:0071941)5.18921195
33regulation of apoptotic cell clearance (GO:2000425)5.15408313
34cysteine metabolic process (GO:0006534)5.14093549
35regulation of complement activation (GO:0030449)5.13373939
36reverse cholesterol transport (GO:0043691)5.10628864
37serine family amino acid catabolic process (GO:0009071)5.05285848
38protein-lipid complex remodeling (GO:0034368)5.04757588
39macromolecular complex remodeling (GO:0034367)5.04757588
40plasma lipoprotein particle remodeling (GO:0034369)5.04757588
41bile acid metabolic process (GO:0008206)4.98814416
42regulation of triglyceride catabolic process (GO:0010896)4.97479552
43phospholipid efflux (GO:0033700)4.89771936
44aromatic amino acid family metabolic process (GO:0009072)4.87779059
45cytolysis (GO:0019835)4.87574087
46negative regulation of sterol transport (GO:0032372)4.80858542
47negative regulation of cholesterol transport (GO:0032375)4.80858542
48fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.77566898
49tyrosine metabolic process (GO:0006570)4.73571944
50negative regulation of hemostasis (GO:1900047)4.71999647
51negative regulation of blood coagulation (GO:0030195)4.71999647
52acylglycerol homeostasis (GO:0055090)4.62827717
53triglyceride homeostasis (GO:0070328)4.62827717
54homocysteine metabolic process (GO:0050667)4.61952677
55drug metabolic process (GO:0017144)4.58170469
56negative regulation of complement activation (GO:0045916)4.55156295
57alpha-amino acid catabolic process (GO:1901606)4.54194610
58plasma lipoprotein particle clearance (GO:0034381)4.51037041
59amino-acid betaine metabolic process (GO:0006577)4.48789017
60cholesterol efflux (GO:0033344)4.45159269
61lysine catabolic process (GO:0006554)4.37272738
62lysine metabolic process (GO:0006553)4.37272738
63killing of cells in other organism involved in symbiotic interaction (GO:0051883)4.35206277
64disruption of cells of other organism involved in symbiotic interaction (GO:0051818)4.35206277
65positive regulation of hemostasis (GO:1900048)4.34029457
66positive regulation of blood coagulation (GO:0030194)4.34029457
67indolalkylamine metabolic process (GO:0006586)4.33324721
68negative regulation of coagulation (GO:0050819)4.31917419
69cellular ketone body metabolic process (GO:0046950)4.27825563
70negative regulation of wound healing (GO:0061045)4.27692333
71bile acid and bile salt transport (GO:0015721)4.27506835
72amine catabolic process (GO:0009310)4.26893520
73cellular biogenic amine catabolic process (GO:0042402)4.26893520
74acute-phase response (GO:0006953)4.24035017
75glycine metabolic process (GO:0006544)4.23598244
76coenzyme catabolic process (GO:0009109)4.22190731
77plasma lipoprotein particle assembly (GO:0034377)4.20592333
78fibrinolysis (GO:0042730)4.20208824
79imidazole-containing compound metabolic process (GO:0052803)4.17190473
80ethanol metabolic process (GO:0006067)4.16664947
81oxidative demethylation (GO:0070989)4.16636787
82cellular amino acid catabolic process (GO:0009063)4.16376103
83benzene-containing compound metabolic process (GO:0042537)4.15334895
84low-density lipoprotein particle remodeling (GO:0034374)4.10388416
85cellular glucuronidation (GO:0052695)4.09130323
86acute inflammatory response (GO:0002526)4.09055096
87glutamate metabolic process (GO:0006536)4.07810116
88blood coagulation, intrinsic pathway (GO:0007597)4.04274046
89serine family amino acid metabolic process (GO:0009069)4.01210718
90negative regulation of lipase activity (GO:0060192)4.00791456
91arginine metabolic process (GO:0006525)4.00272827
92positive regulation of coagulation (GO:0050820)3.97028146
93heme transport (GO:0015886)3.96719776
94cellular modified amino acid catabolic process (GO:0042219)3.96071642
95very-low-density lipoprotein particle assembly (GO:0034379)3.94223309
96opsonization (GO:0008228)3.93800092
97protein activation cascade (GO:0072376)3.91251568
98complement activation, classical pathway (GO:0006958)3.90415851
99positive regulation of triglyceride lipase activity (GO:0061365)3.90414102
100positive regulation of lipoprotein lipase activity (GO:0051006)3.90414102
101positive regulation of fatty acid biosynthetic process (GO:0045723)3.88687314
102aldehyde catabolic process (GO:0046185)3.88352416
103drug catabolic process (GO:0042737)3.87659987
104complement activation (GO:0006956)3.87277755
105dicarboxylic acid biosynthetic process (GO:0043650)3.85943274
106serine family amino acid biosynthetic process (GO:0009070)3.85217775
107negative regulation of protein activation cascade (GO:2000258)3.83467317
108positive regulation of lipid catabolic process (GO:0050996)3.83419830
109plasma lipoprotein particle organization (GO:0071827)3.81913104
110cofactor catabolic process (GO:0051187)3.78687683
111regulation of acute inflammatory response (GO:0002673)3.78678873
112ethanol oxidation (GO:0006069)3.78379338
113protein-lipid complex assembly (GO:0065005)3.74320121
114cholesterol homeostasis (GO:0042632)3.71431199
115positive regulation of heterotypic cell-cell adhesion (GO:0034116)3.69806996
116ketone body metabolic process (GO:1902224)3.69572809
117phospholipid homeostasis (GO:0055091)3.67434884
118sterol homeostasis (GO:0055092)3.65224232
119regulation of bile acid biosynthetic process (GO:0070857)3.64628841
120carboxylic acid catabolic process (GO:0046395)3.64115769
121organic acid catabolic process (GO:0016054)3.64115769
122uronic acid metabolic process (GO:0006063)3.62714021
123glucuronate metabolic process (GO:0019585)3.62714021
124phenylpropanoid metabolic process (GO:0009698)3.60992206
125protein-lipid complex subunit organization (GO:0071825)3.57540802
126negative regulation of humoral immune response (GO:0002921)3.56802054
127flavonoid metabolic process (GO:0009812)3.49874260
128lipoprotein metabolic process (GO:0042157)3.43407168
129polyketide metabolic process (GO:0030638)3.43126133
130doxorubicin metabolic process (GO:0044598)3.43126133
131daunorubicin metabolic process (GO:0044597)3.43126133
132cholesterol transport (GO:0030301)3.32360958

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse8.28350790
2* EGR1_23403033_ChIP-Seq_LIVER_Mouse7.10959180
3* PPARA_22158963_ChIP-Seq_LIVER_Mouse7.08726091
4* LXR_22158963_ChIP-Seq_LIVER_Mouse6.41972486
5CEBPA_23403033_ChIP-Seq_LIVER_Mouse5.40346870
6FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.29858815
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.85796692
8CEBPB_23403033_ChIP-Seq_LIVER_Mouse4.24891679
9NR1I2_20693526_ChIP-Seq_LIVER_Mouse4.09990861
10TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.03994908
11* ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.9489419
12HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.97125473
13TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.89268292
14* FOXA2_19822575_ChIP-Seq_HepG2_Human1.59041401
15HTT_18923047_ChIP-ChIP_STHdh_Human1.53870256
16TRIM28_21343339_ChIP-Seq_HEK293_Human1.50032070
17CLOCK_20551151_ChIP-Seq_293T_Human1.45656779
18CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.43998006
19GATA1_22025678_ChIP-Seq_K562_Human1.40773287
20* HNF4A_19822575_ChIP-Seq_HepG2_Human1.39372738
21THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.31410603
22STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.29433257
23TCF4_18268006_ChIP-ChIP_LS174T_Human1.25838996
24RXRA_24833708_ChIP-Seq_LIVER_Mouse1.18842008
25STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.15183839
26TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.10799395
27IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.09713955
28IRF8_22096565_ChIP-ChIP_GC-B_Human1.09204874
29ESR1_15608294_ChIP-ChIP_MCF-7_Human1.08577370
30ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.02287470
31FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.98948234
32PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.97820747
33MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.97172324
34PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.96581349
35SOX2_27498859_Chip-Seq_STOMACH_Mouse0.91980712
36* CDX2_20551321_ChIP-Seq_CACO-2_Human0.89178921
37PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.85606841
38AUTS2_25519132_ChIP-Seq_293T-REX_Human0.83629556
39KAP1_22055183_ChIP-Seq_ESCs_Mouse0.83384939
40GATA4_25053715_ChIP-Seq_YYC3_Human0.80891483
41BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.79810812
42ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.79707526
43AR_21909140_ChIP-Seq_LNCAP_Human0.79458050
44RARG_19884340_ChIP-ChIP_MEFs_Mouse0.78020787
45Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.75215013
46NFE2_27457419_Chip-Seq_LIVER_Mouse0.74755237
47RARA_24833708_ChIP-Seq_LIVER_Mouse0.73115619
48TP63_17297297_ChIP-ChIP_HaCaT_Human0.72215456
49SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.71974239
50CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.71932615
51AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.71858373
52RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.68714669
53SALL4_18804426_ChIP-ChIP_XEN_Mouse0.68273855
54PCGF2_27294783_Chip-Seq_NPCs_Mouse0.67678419
55SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.66438732
56NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.66187952
57NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.65997915
58NRF2_20460467_ChIP-Seq_MEFs_Mouse0.65997915
59HIF1A_21447827_ChIP-Seq_MCF-7_Human0.65389985
60SMAD1_18555785_Chip-Seq_ESCs_Mouse0.64858168
61POU5F1_16518401_ChIP-PET_MESCs_Mouse0.64768332
62ESR2_21235772_ChIP-Seq_MCF-7_Human0.64078175
63ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.63270963
64E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.62429526
65BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.61686495
66RARB_24833708_ChIP-Seq_LIVER_Mouse0.60836574
67SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.58917608
68SUZ12_27294783_Chip-Seq_NPCs_Mouse0.57528920
69* RAD21_21589869_ChIP-Seq_MESCs_Mouse0.57490307
70GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.57274137
71AR_20517297_ChIP-Seq_VCAP_Human0.57192591
72NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.57173413
73ESRRB_18555785_Chip-Seq_ESCs_Mouse0.56861863
74FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.56593989
75ZNF263_19887448_ChIP-Seq_K562_Human0.56459625
76RUNX1_27457419_Chip-Seq_LIVER_Mouse0.55907804
77OCT4_18555785_Chip-Seq_ESCs_Mouse0.55143053
78SOX2_21211035_ChIP-Seq_LN229_Human0.55090090
79EZH2_27294783_Chip-Seq_NPCs_Mouse0.54976800
80NFIB_24661679_ChIP-Seq_LUNG_Mouse0.54234100
81FOXA1_25552417_ChIP-Seq_VCAP_Human0.53965841
82NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.53460509
83* CEBPB_22108803_ChIP-Seq_LS180_Human0.53181876
84FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.51846667
85CTNNB1_20460455_ChIP-Seq_HCT116_Human0.51804683
86HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.51774826
87NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.51368782
88PU1_27457419_Chip-Seq_LIVER_Mouse0.50768994
89CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.50683696
90* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.50621766
91RAC3_21632823_ChIP-Seq_H3396_Human0.49737943
92CDX2_19796622_ChIP-Seq_MESCs_Mouse0.49165407
93ESET_19884257_ChIP-Seq_ESCs_Mouse0.49152413
94ESR1_21235772_ChIP-Seq_MCF-7_Human0.48521075
95EGR1_19032775_ChIP-ChIP_M12_Human0.48275634
96CBP_21632823_ChIP-Seq_H3396_Human0.47976691
97ZFX_18555785_Chip-Seq_ESCs_Mouse0.47660797
98ERG_21242973_ChIP-ChIP_JURKAT_Human0.47643778
99STAT1_17558387_ChIP-Seq_HELA_Human0.47391941
100KLF4_18555785_Chip-Seq_ESCs_Mouse0.47135580
101MYC_19915707_ChIP-ChIP_AK7_Human0.46937488
102DNAJC2_21179169_ChIP-ChIP_NT2_Human0.46588172
103ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.46377690
104TP53_18474530_ChIP-ChIP_U2OS_Human0.46262121
105P53_21459846_ChIP-Seq_SAOS-2_Human0.46014212
106STAT3_1855785_ChIP-Seq_MESCs_Mouse0.45619229
107SOX11_22085726_ChIP-Seq_ESNs_Mouse0.45079748
108GATA3_24758297_ChIP-Seq_MCF-7_Human0.44792916
109NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.44678464
110* PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.44632923
111IRF1_19129219_ChIP-ChIP_H3396_Human0.44110434
112PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.44025582
113CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.43374624
114BCAT_22108803_ChIP-Seq_LS180_Human0.42800043
115ESR1_20079471_ChIP-ChIP_T-47D_Human0.42430095
116TAF15_26573619_Chip-Seq_HEK293_Human0.41256695
117LXR_22292898_ChIP-Seq_THP-1_Human0.41110031
118GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.40533428
119FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.40521030
120TAF2_19829295_ChIP-Seq_ESCs_Human0.39074445
121FOXH1_21741376_ChIP-Seq_EPCs_Human0.39029838
122SOX2_20726797_ChIP-Seq_SW620_Human0.38894140
123PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.38731195
124SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.38623417
125STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.38622226
126SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.38428085
127GATA6_25053715_ChIP-Seq_YYC3_Human0.38164597
128MYC_27129775_Chip-Seq_CORNEA_Mouse0.37580333
129EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.36969778
130GATA2_19941826_ChIP-Seq_K562_Human0.36656369
131FOXO3_23340844_ChIP-Seq_DLD1_Human0.36373394
132SPI1_26923725_Chip-Seq_HPCs_Mouse0.36337752
133GATA1_19941827_ChIP-Seq_MEL_Mouse0.35701096
134* CDX2_22108803_ChIP-Seq_LS180_Human0.35248282
135NCOR_22424771_ChIP-Seq_293T_Human0.35116136
136PPAR_26484153_Chip-Seq_NCI-H1993_Human0.34656864
137LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.34521834
138ERG_20517297_ChIP-Seq_VCAP_Human0.34229968
139GATA1_19941826_ChIP-Seq_K562_Human0.33930748

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.34199567
2MP0005360_urolithiasis7.42204440
3MP0005085_abnormal_gallbladder_physiolo6.37949975
4MP0005365_abnormal_bile_salt6.20123358
5MP0008875_abnormal_xenobiotic_pharmacok5.06864557
6MP0003806_abnormal_nucleotide_metabolis4.09500380
7MP0003252_abnormal_bile_duct3.80653462
8MP0010329_abnormal_lipoprotein_level3.59675803
9MP0009840_abnormal_foam_cell3.34427182
10MP0005083_abnormal_biliary_tract3.04516975
11MP0003195_calcinosis2.83446319
12MP0005332_abnormal_amino_acid2.76655030
13MP0003191_abnormal_cellular_cholesterol2.64667853
14MP0001666_abnormal_nutrient_absorption2.56957365
15MP0000609_abnormal_liver_physiology2.15743985
16MP0004019_abnormal_vitamin_homeostasis2.10349908
17MP0002118_abnormal_lipid_homeostasis2.07727270
18MP0002138_abnormal_hepatobiliary_system2.02525579
19MP0003868_abnormal_feces_composition1.87521966
20MP0005319_abnormal_enzyme/_coenzyme1.81511206
21MP0003122_maternal_imprinting1.78343261
22MP0001764_abnormal_homeostasis1.69983100
23MP0009697_abnormal_copulation1.66683137
24MP0005584_abnormal_enzyme/coenzyme_acti1.53598013
25MP0005451_abnormal_body_composition1.44153572
26MP0003011_delayed_dark_adaptation1.42228164
27MP0001915_intracranial_hemorrhage1.41516441
28MP0005647_abnormal_sex_gland1.29332150
29MP0003656_abnormal_erythrocyte_physiolo1.28038833
30MP0003186_abnormal_redox_activity1.27579795
31MP0009643_abnormal_urine_homeostasis1.27062052
32MP0009764_decreased_sensitivity_to1.24255993
33MP0000598_abnormal_liver_morphology1.15925345
34MP0000604_amyloidosis1.15700572
35MP0009763_increased_sensitivity_to1.08995083
36MP0003705_abnormal_hypodermis_morpholog1.05545307
37MP0005636_abnormal_mineral_homeostasis1.03140870
38MP0002089_abnormal_postnatal_growth/wei1.02478365
39MP0005058_abnormal_lysosome_morphology1.01752674
40MP0002254_reproductive_system_inflammat1.01466217
41MP0000566_synostosis1.00954378
42MP0010368_abnormal_lymphatic_system1.00273866
43MP0008469_abnormal_protein_level0.96184786
44MP0005670_abnormal_white_adipose0.90266663
45MP0009642_abnormal_blood_homeostasis0.90086345
46MP0009765_abnormal_xenobiotic_induced0.86303496
47MP0002876_abnormal_thyroid_physiology0.82649227
48MP0005408_hypopigmentation0.81802647
49MP0003123_paternal_imprinting0.79796825
50MP0005376_homeostasis/metabolism_phenot0.78937272
51MP0005220_abnormal_exocrine_pancreas0.78024534
52MP0005084_abnormal_gallbladder_morpholo0.77878093
53MP0002282_abnormal_trachea_morphology0.75498721
54MP0002078_abnormal_glucose_homeostasis0.74647062
55MP0006036_abnormal_mitochondrial_physio0.74177636
56MP0002971_abnormal_brown_adipose0.71835014
57MP0001661_extended_life_span0.70935318
58MP0003172_abnormal_lysosome_physiology0.70722107
59MP0003690_abnormal_glial_cell0.70617089
60MP0009053_abnormal_anal_canal0.70274710
61MP0005334_abnormal_fat_pad0.68952566
62MP0005464_abnormal_platelet_physiology0.67999227
63MP0001756_abnormal_urination0.63708900
64MP0004272_abnormal_basement_membrane0.63113608
65MP0003879_abnormal_hair_cell0.62938808
66MP0000639_abnormal_adrenal_gland0.62883142
67MP0005535_abnormal_body_temperature0.61667903
68MP0005167_abnormal_blood-brain_barrier0.58007295
69MP0004130_abnormal_muscle_cell0.57479229
70MP0005266_abnormal_metabolism0.56916383
71MP0005448_abnormal_energy_balance0.53476541
72MP0003329_amyloid_beta_deposits0.53422809
73MP0005395_other_phenotype0.52661812
74MP0005409_darkened_coat_color0.52500745
75MP0003436_decreased_susceptibility_to0.52053066
76MP0003724_increased_susceptibility_to0.51406926
77MP0002136_abnormal_kidney_physiology0.51047570
78MP0003638_abnormal_response/metabolism_0.49569934
79MP0006035_abnormal_mitochondrial_morpho0.49487724
80MP0005187_abnormal_penis_morphology0.48243820
81MP0003718_maternal_effect0.45621365
82MP0008873_increased_physiological_sensi0.45042643
83MP0000920_abnormal_myelination0.44819670
84MP0002249_abnormal_larynx_morphology0.44488165
85MP0008874_decreased_physiological_sensi0.44393167
86MP0005166_decreased_susceptibility_to0.43361170
87MP0002132_abnormal_respiratory_system0.43138035
88MP0002928_abnormal_bile_duct0.42580837
89MP0004782_abnormal_surfactant_physiolog0.42272208
90MP0003632_abnormal_nervous_system0.42005821
91MP0003075_altered_response_to0.41834575
92MP0005248_abnormal_Harderian_gland0.41730492
93MP0003953_abnormal_hormone_level0.39747303
94MP0006054_spinal_hemorrhage0.39125454
95MP0000579_abnormal_nail_morphology0.38361959
96MP0002822_catalepsy0.38314830
97MP0002933_joint_inflammation0.35975056
98MP0009780_abnormal_chondrocyte_physiolo0.35571374
99MP0004883_abnormal_blood_vessel0.35178918
100MP0003633_abnormal_nervous_system0.34995563
101MP0000249_abnormal_blood_vessel0.34826619
102MP0002128_abnormal_blood_circulation0.34727580
103MP0005666_abnormal_adipose_tissue0.34685438
104MP0001845_abnormal_inflammatory_respons0.34188918
105MP0001881_abnormal_mammary_gland0.33721860
106MP0008872_abnormal_physiological_respon0.33515162
107MP0006082_CNS_inflammation0.33483768
108MP0001324_abnormal_eye_pigmentation0.32879313
109MP0009115_abnormal_fat_cell0.32103224
110MP0002168_other_aberrant_phenotype0.31190201
111MP0009384_cardiac_valve_regurgitation0.30791637
112MP0004381_abnormal_hair_follicle0.30781175
113MP0003631_nervous_system_phenotype0.30709344
114MP0000230_abnormal_systemic_arterial0.30646729
115MP0005164_abnormal_response_to0.30496902
116MP0003566_abnormal_cell_adhesion0.30314249
117MP0001243_abnormal_dermal_layer0.30124179
118MP0001853_heart_inflammation0.29552986
119MP0009785_altered_susceptibility_to0.28955078
120MP0005257_abnormal_intraocular_pressure0.28474189
121MP0009672_abnormal_birth_weight0.28293884
122MP0003943_abnormal_hepatobiliary_system0.27937436
123MP0002909_abnormal_adrenal_gland0.27615081
124MP0003183_abnormal_peptide_metabolism0.27597059
125MP0002837_dystrophic_cardiac_calcinosis0.27512967
126MP0002135_abnormal_kidney_morphology0.27289718
127MP0002970_abnormal_white_adipose0.27162122
128MP0000858_altered_metastatic_potential0.26959538
129MP0005377_hearing/vestibular/ear_phenot0.26899275
130MP0003878_abnormal_ear_physiology0.26899275
131MP0002796_impaired_skin_barrier0.26525348
132MP0005023_abnormal_wound_healing0.25922596

Predicted human phenotypes

RankGene SetZ-score
1Deep venous thrombosis (HP:0002625)7.54028537
2Abnormality of aromatic amino acid family metabolism (HP:0004338)7.27092214
3Intrahepatic cholestasis (HP:0001406)7.18939366
4Prolonged partial thromboplastin time (HP:0003645)6.95041894
5Abnormality of monocarboxylic acid metabolism (HP:0010996)6.72040802
6Hypobetalipoproteinemia (HP:0003563)6.39456995
7Xanthomatosis (HP:0000991)6.17262966
8Hyperlipoproteinemia (HP:0010980)5.67214040
9Complement deficiency (HP:0004431)5.63464511
10Joint hemorrhage (HP:0005261)5.11837992
11Abnormality of the common coagulation pathway (HP:0010990)4.97727795
12Hypolipoproteinemia (HP:0010981)4.85863590
13Hyperammonemia (HP:0001987)4.54886583
14Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.45424501
15Epidermoid cyst (HP:0200040)4.38720524
16Abnormality of methionine metabolism (HP:0010901)4.32705541
17Hypoalphalipoproteinemia (HP:0003233)4.31871187
18Abnormality of sulfur amino acid metabolism (HP:0004339)4.28551896
19Hyperglycinemia (HP:0002154)4.28225919
20Ketosis (HP:0001946)4.16187166
21Abnormality of aspartate family amino acid metabolism (HP:0010899)4.14872114
22Abnormality of complement system (HP:0005339)4.11885005
23Fat malabsorption (HP:0002630)4.10797979
24Abnormality of glutamine family amino acid metabolism (HP:0010902)4.09255584
25Abnormality of the intrinsic pathway (HP:0010989)4.02352518
26Abnormality of pyrimidine metabolism (HP:0004353)3.95123876
27Hypoglycemic coma (HP:0001325)3.85423900
28Spontaneous abortion (HP:0005268)3.81079618
29Hyperglycinuria (HP:0003108)3.80943053
30Abnormality of glycine metabolism (HP:0010895)3.77533214
31Abnormality of serine family amino acid metabolism (HP:0010894)3.77533214
32Conjugated hyperbilirubinemia (HP:0002908)3.73825867
33Hypercholesterolemia (HP:0003124)3.62424335
34Hyperbilirubinemia (HP:0002904)3.28771173
35Abnormality of fatty-acid metabolism (HP:0004359)3.27414867
36Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.24907763
37Steatorrhea (HP:0002570)3.12831637
38Abnormality of nucleobase metabolism (HP:0010932)3.04265912
39Purpura (HP:0000979)3.01556999
40Abnormality of serum amino acid levels (HP:0003112)2.99856524
41Delayed CNS myelination (HP:0002188)2.95325810
42Ketoacidosis (HP:0001993)2.95220948
43Myocardial infarction (HP:0001658)2.94728730
44Hepatocellular carcinoma (HP:0001402)2.91704398
45Systemic lupus erythematosus (HP:0002725)2.88186969
46Glomerulonephritis (HP:0000099)2.87757312
47Hypochromic microcytic anemia (HP:0004840)2.87486966
48Amyloidosis (HP:0011034)2.72150690
49Gingival bleeding (HP:0000225)2.71787734
50Metabolic acidosis (HP:0001942)2.70212437
51Skin nodule (HP:0200036)2.66378151
52Vascular calcification (HP:0004934)2.64607510
53Abnormality of purine metabolism (HP:0004352)2.58836930
54Osteomalacia (HP:0002749)2.57684083
55Lethargy (HP:0001254)2.56934077
56Hypoglycemic seizures (HP:0002173)2.54948758
57Dicarboxylic aciduria (HP:0003215)2.45972802
58Abnormality of dicarboxylic acid metabolism (HP:0010995)2.45972802
59Recurrent gram-negative bacterial infections (HP:0005420)2.44840759
60Acanthocytosis (HP:0001927)2.43596181
61Mitral stenosis (HP:0001718)2.41042410
62Cerebral edema (HP:0002181)2.39762899
63Menorrhagia (HP:0000132)2.38214598
64Spastic diplegia (HP:0001264)2.37879482
65Thrombophlebitis (HP:0004418)2.35823609
66Abnormal gallbladder morphology (HP:0012437)2.33925115
67Cardiovascular calcification (HP:0011915)2.33824715
68Irritability (HP:0000737)2.28799972
69Cholelithiasis (HP:0001081)2.27913473
70Abnormal tarsal ossification (HP:0008369)2.27286187
71Neonatal onset (HP:0003623)2.26430616
72Gout (HP:0001997)2.22226494
73Pulmonary embolism (HP:0002204)2.21973558
74Arthropathy (HP:0003040)2.20225502
75Esophageal varix (HP:0002040)2.18831717
76Cholecystitis (HP:0001082)2.17738794
77Abnormal gallbladder physiology (HP:0012438)2.17738794
78Pancreatitis (HP:0001733)2.16804350
79Malnutrition (HP:0004395)2.15647109
80Late onset (HP:0003584)2.14797598
81Sensorimotor neuropathy (HP:0007141)2.13612841
82Abnormality of iron homeostasis (HP:0011031)2.12268680
83Increased serum pyruvate (HP:0003542)2.11591483
84Abnormality of transition element cation homeostasis (HP:0011030)2.09862484
85Enlarged kidneys (HP:0000105)2.09418369
86Brushfield spots (HP:0001088)2.07723915
87Abnormal delivery (HP:0001787)2.06207742
88Hyperinsulinemic hypoglycemia (HP:0000825)2.04328059
89Vomiting (HP:0002013)2.04098070
90Generalized aminoaciduria (HP:0002909)2.03408041
91Abnormality of carpal bone ossification (HP:0006257)2.02100307
92Nephritis (HP:0000123)2.01977306
93Opisthotonus (HP:0002179)2.01897997
94Hemorrhage of the eye (HP:0011885)1.97064398
95Poikilocytosis (HP:0004447)1.96478317
96Epistaxis (HP:0000421)1.96444682
97Rickets (HP:0002748)1.92538936
98Hypophosphatemic rickets (HP:0004912)1.91315374
99Abnormality of the Achilles tendon (HP:0005109)1.91224456
100Abnormality of the gallbladder (HP:0005264)1.90904467
101Renal cortical cysts (HP:0000803)1.89054199
102Potter facies (HP:0002009)1.88228214
103Facial shape deformation (HP:0011334)1.88228214
104Abnormality of glycolysis (HP:0004366)1.87689721
105Elevated hepatic transaminases (HP:0002910)1.81051711
106Abnormality of proline metabolism (HP:0010907)1.80913638
107Hydroxyprolinuria (HP:0003080)1.80913638
108Increased serum ferritin (HP:0003281)1.80674264
109Reduced antithrombin III activity (HP:0001976)1.80375308
110Status epilepticus (HP:0002133)1.78818490
111Abnormal enzyme/coenzyme activity (HP:0012379)1.76763281
112Alkalosis (HP:0001948)1.75373166
113Fair hair (HP:0002286)1.74185367
114Joint swelling (HP:0001386)1.73949550
115Hyperglycemia (HP:0003074)1.73812577
116Abnormal cartilage morphology (HP:0002763)1.73221347
117Gangrene (HP:0100758)1.69617478
118Elevated alkaline phosphatase (HP:0003155)1.68174649
119Pancreatic islet-cell hyperplasia (HP:0004510)1.60425413
120Hyperphosphaturia (HP:0003109)1.59700193
121Flat acetabular roof (HP:0003180)1.57923454
122Abnormality of alkaline phosphatase activity (HP:0004379)1.57076238
123Bifid scrotum (HP:0000048)1.54475308
124Small epiphyses (HP:0010585)1.53424083
125Neoplasm of the liver (HP:0002896)1.50806181
126Glycosuria (HP:0003076)1.48871922
127Abnormality of urine glucose concentration (HP:0011016)1.48871922
128Widely patent fontanelles and sutures (HP:0004492)1.46526211
129Abnormal hand bone ossification (HP:0010660)1.46071795
130Vaginal fistula (HP:0004320)1.43229967

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK7.10705145
2ERN15.07917111
3FGFR44.56895794
4SIK14.25189061
5TAOK33.60786151
6INSRR3.10688350
7ERBB42.86088560
8WNK42.55803175
9CDK122.37434409
10MAP2K42.17901321
11MST1R2.16385697
12PIK3CG2.02624132
13PDGFRA1.90712143
14LATS11.90531976
15DAPK21.84149843
16MAPK111.83559071
17TYK21.80651752
18FGFR11.75106258
19TYRO31.72896357
20PKN21.68257456
21FLT31.67695987
22FRK1.65940051
23PTK61.49960117
24NEK91.39803777
25TRIB31.35655754
26ABL21.34616201
27EIF2AK11.30841353
28JAK21.26704615
29EPHA31.22103766
30NTRK31.18816206
31MAP3K141.18377173
32MAP3K21.17780749
33KDR1.16817906
34PINK11.13413479
35FGFR21.12278339
36JAK11.11854726
37WNK11.09414958
38TBK11.08632941
39ERBB21.05284244
40EPHB11.02924535
41PRKAA21.01700368
42MAP3K71.01290081
43MAP2K30.96895358
44STK38L0.96375909
45AKT30.96283259
46SIK20.95102579
47EEF2K0.94944922
48MAPK40.91845519
49GRK60.89629679
50DDR20.88351598
51BRSK20.86590868
52CSNK1E0.86148833
53PRKCZ0.85739926
54MAPKAPK30.84807617
55MAP3K30.84163133
56IRAK30.81733775
57MET0.78524438
58TIE10.78121081
59MAPK120.77689921
60CAMK2G0.75314596
61MAPK150.75051076
62MAP3K110.73857187
63PRKACG0.73597458
64IKBKE0.70852592
65MAP2K60.66997674
66NEK10.66656141
67CSK0.65723378
68CDK70.65554174
69SGK10.65481876
70RPS6KB10.63056606
71MAPK70.62030195
72CDK60.61316255
73FGFR30.60889771
74SGK30.60621896
75LATS20.60615807
76CAMKK20.59797172
77DYRK1B0.58601461
78CDC42BPA0.58173149
79FER0.57876788
80GSK3A0.57827038
81PRKAA10.57314812
82GRK10.56974206
83PRKG10.56905643
84CSF1R0.55493670
85CAMK1D0.54630965
86SCYL20.54602779
87TGFBR20.54069336
88RIPK10.53405640
89BCR0.53274739
90SGK20.53248379
91PIK3CA0.52699425
92FGR0.51917735
93CSNK1D0.51792802
94BRSK10.50908150
95PRKCQ0.49677755
96STK390.48486944
97MAP3K100.47434567
98SRC0.46178701
99PDPK10.44988449
100PKN10.44840729
101IRAK10.44795954
102IGF1R0.43601960
103TAOK20.43133098
104PTK20.42895253
105RPS6KA30.42699078
106CSNK2A20.42523017
107KSR20.42172215
108CSNK2A10.40552895
109MAP2K10.40378781
110PRKCG0.40084723
111CSNK1G10.38825864
112MAP3K50.38200583
113PRKACA0.36852755
114EPHA40.35157340
115NUAK10.35153561
116ZAP700.35136493
117BRD40.33730328
118PRKCB0.33607492
119CAMK40.31989505
120MATK0.31791759
121EGFR0.31011101
122SGK4940.30867929
123SGK2230.30867929
124MTOR0.29125008
125MAP3K130.29012339
126EPHA20.27998250
127RET0.27345458
128PRKCA0.27159205
129PDK10.26348843
130CDK40.25835987
131ICK0.25792441
132MAP3K60.24573565
133JAK30.24462761
134IRAK20.23761122
135MAP3K10.23147914
136PBK0.23107950
137PRKACB0.20909035
138MAP2K20.20734610
139MAPK30.20104388
140NLK0.19736646

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.53117179
2Nitrogen metabolism_Homo sapiens_hsa009103.48892845
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.40326436
4Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.32527270
5Arginine biosynthesis_Homo sapiens_hsa002203.11715623
6Complement and coagulation cascades_Homo sapiens_hsa046103.03002993
7Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.66444563
8Tryptophan metabolism_Homo sapiens_hsa003802.65412585
9Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.56596228
10Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.54070689
11Fatty acid degradation_Homo sapiens_hsa000712.43180690
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.34570285
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.24831601
14Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.17749839
15Peroxisome_Homo sapiens_hsa041462.09342956
16Butanoate metabolism_Homo sapiens_hsa006502.07643196
17Chemical carcinogenesis_Homo sapiens_hsa052042.00996424
18Staphylococcus aureus infection_Homo sapiens_hsa051501.98537871
19Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.96012381
20Steroid hormone biosynthesis_Homo sapiens_hsa001401.90825032
21Propanoate metabolism_Homo sapiens_hsa006401.89249425
22Histidine metabolism_Homo sapiens_hsa003401.89153454
23PPAR signaling pathway_Homo sapiens_hsa033201.87429727
24Drug metabolism - other enzymes_Homo sapiens_hsa009831.77584602
25Fatty acid metabolism_Homo sapiens_hsa012121.75667956
26Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.73091909
27beta-Alanine metabolism_Homo sapiens_hsa004101.70281308
28Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.70174583
29Caffeine metabolism_Homo sapiens_hsa002321.66344949
30Retinol metabolism_Homo sapiens_hsa008301.65622509
31Selenocompound metabolism_Homo sapiens_hsa004501.58323912
32Phenylalanine metabolism_Homo sapiens_hsa003601.57687242
33Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.55896873
34Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.55578666
35Bile secretion_Homo sapiens_hsa049761.46610518
362-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.45755887
37Tyrosine metabolism_Homo sapiens_hsa003501.42178269
38Sulfur metabolism_Homo sapiens_hsa009201.39124024
39Cysteine and methionine metabolism_Homo sapiens_hsa002701.34860455
40Pyruvate metabolism_Homo sapiens_hsa006201.28889095
41Starch and sucrose metabolism_Homo sapiens_hsa005001.27642101
42Fatty acid elongation_Homo sapiens_hsa000621.26521810
43Folate biosynthesis_Homo sapiens_hsa007901.24917291
44ABC transporters_Homo sapiens_hsa020101.22605358
45Steroid biosynthesis_Homo sapiens_hsa001001.21092000
46Fat digestion and absorption_Homo sapiens_hsa049751.19908720
47Biosynthesis of amino acids_Homo sapiens_hsa012301.17976682
48Maturity onset diabetes of the young_Homo sapiens_hsa049501.07897874
49Carbon metabolism_Homo sapiens_hsa012001.07490123
50Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.04833044
51Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.01193697
52Arginine and proline metabolism_Homo sapiens_hsa003300.97621379
53Cyanoamino acid metabolism_Homo sapiens_hsa004600.96746626
54Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.96127612
55Sulfur relay system_Homo sapiens_hsa041220.95388091
56Vitamin digestion and absorption_Homo sapiens_hsa049770.90949672
57Vitamin B6 metabolism_Homo sapiens_hsa007500.86623757
58Lysine degradation_Homo sapiens_hsa003100.79202026
59Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.78505023
60One carbon pool by folate_Homo sapiens_hsa006700.75460411
61Glutathione metabolism_Homo sapiens_hsa004800.68088053
62Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.65260573
63Glycerolipid metabolism_Homo sapiens_hsa005610.63366922
64Pentose phosphate pathway_Homo sapiens_hsa000300.56876437
65Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.50219266
66Fatty acid biosynthesis_Homo sapiens_hsa000610.47221352
67Metabolic pathways_Homo sapiens_hsa011000.46410970
68Other glycan degradation_Homo sapiens_hsa005110.45655858
69Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.37092988
70Prion diseases_Homo sapiens_hsa050200.36268787
71Fructose and mannose metabolism_Homo sapiens_hsa000510.28126155
72alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.25644414
73Galactose metabolism_Homo sapiens_hsa000520.24954788
74Insulin resistance_Homo sapiens_hsa049310.21490111
75Linoleic acid metabolism_Homo sapiens_hsa005910.21321808
76Adipocytokine signaling pathway_Homo sapiens_hsa049200.20936699
77N-Glycan biosynthesis_Homo sapiens_hsa005100.15905855
78Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.15587753
79Glycerophospholipid metabolism_Homo sapiens_hsa005640.13918479
80Glucagon signaling pathway_Homo sapiens_hsa049220.07855179
81Mineral absorption_Homo sapiens_hsa049780.05691666
82AMPK signaling pathway_Homo sapiens_hsa041520.00544229
83Longevity regulating pathway - mammal_Homo sapiens_hsa04211-0.2536214
84RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622-0.2310397
85Amoebiasis_Homo sapiens_hsa05146-0.2282363
86Bladder cancer_Homo sapiens_hsa05219-0.2177048
87Pertussis_Homo sapiens_hsa05133-0.2112718
88Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.2012054
89Serotonergic synapse_Homo sapiens_hsa04726-0.1831046
90Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1768249
91Circadian rhythm_Homo sapiens_hsa04710-0.1751869
92Protein digestion and absorption_Homo sapiens_hsa04974-0.1585939
93Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1554397
94Renin-angiotensin system_Homo sapiens_hsa04614-0.1464817
95Arachidonic acid metabolism_Homo sapiens_hsa00590-0.1421436
96Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.1403636
97ECM-receptor interaction_Homo sapiens_hsa04512-0.1334012
98Hepatitis C_Homo sapiens_hsa05160-0.1313948
99Insulin signaling pathway_Homo sapiens_hsa04910-0.1306922
100Systemic lupus erythematosus_Homo sapiens_hsa05322-0.1294775
101Regulation of autophagy_Homo sapiens_hsa04140-0.1291481
102Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.1097620
103African trypanosomiasis_Homo sapiens_hsa05143-0.1091097
104Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.1021755
105Sphingolipid metabolism_Homo sapiens_hsa00600-0.0959992
106Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0918414
107Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932-0.0498538
108Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.0426812
109Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.0157854

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