FHAD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cell wall macromolecule catabolic process (GO:0016998)9.90070600
2cell wall macromolecule metabolic process (GO:0044036)9.90070600
3motile cilium assembly (GO:0044458)9.56263612
4plasma membrane fusion (GO:0045026)9.28861716
5cell-cell recognition (GO:0009988)9.10845065
6binding of sperm to zona pellucida (GO:0007339)9.05398877
7epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.86395967
8regulation of cilium movement (GO:0003352)8.69187944
9spermatid development (GO:0007286)8.61969134
10reproduction (GO:0000003)8.40099067
11piRNA metabolic process (GO:0034587)7.36517292
12male meiosis (GO:0007140)7.10999307
13single fertilization (GO:0007338)7.00608032
14synaptonemal complex organization (GO:0070193)6.60237135
15ventricular system development (GO:0021591)6.59617887
16sperm capacitation (GO:0048240)6.57076958
17negative regulation of inclusion body assembly (GO:0090084)6.55101580
18axoneme assembly (GO:0035082)6.32573024
19synaptonemal complex assembly (GO:0007130)6.05079682
20fertilization (GO:0009566)6.04292006
21spermatogenesis (GO:0007283)5.80247919
22male gamete generation (GO:0048232)5.77747178
23organic cation transport (GO:0015695)5.67340872
24primary alcohol catabolic process (GO:0034310)5.64369449
25regulation of inclusion body assembly (GO:0090083)5.54021790
26regulation of microtubule-based movement (GO:0060632)5.41501063
27gamete generation (GO:0007276)5.31407441
28calcium ion-dependent exocytosis (GO:0017156)5.17882272
29vitamin transmembrane transport (GO:0035461)5.14060050
30microtubule severing (GO:0051013)5.13910352
31male meiosis I (GO:0007141)4.85649406
32ethanol metabolic process (GO:0006067)4.81112508
33cellular process involved in reproduction in multicellular organism (GO:0022412)4.80145676
34germ cell development (GO:0007281)4.79698261
35protein localization to cilium (GO:0061512)4.68613304
36microtubule polymerization or depolymerization (GO:0031109)4.68234963
37intraciliary transport (GO:0042073)4.66751193
38cell recognition (GO:0008037)4.66154111
39DNA methylation involved in gamete generation (GO:0043046)4.59038184
40diterpenoid biosynthetic process (GO:0016102)4.52781417
41left/right pattern formation (GO:0060972)4.50482202
42one-carbon compound transport (GO:0019755)4.48911769
43centriole replication (GO:0007099)4.29464451
44microtubule depolymerization (GO:0007019)4.27205234
45lung epithelium development (GO:0060428)4.23673002
46multicellular organismal reproductive process (GO:0048609)4.22405117
47glomerular epithelial cell development (GO:0072310)4.20587381
48cilium organization (GO:0044782)4.18902830
49nucleoside diphosphate phosphorylation (GO:0006165)4.16693890
50response to xenobiotic stimulus (GO:0009410)4.14977051
51establishment of apical/basal cell polarity (GO:0035089)4.11345682
52regulation of interleukin-5 production (GO:0032674)4.08112680
53protein polyglutamylation (GO:0018095)4.03007875
54cilium assembly (GO:0042384)4.00235325
55negative regulation of T cell differentiation in thymus (GO:0033085)3.96880192
56chromosome organization involved in meiosis (GO:0070192)3.96356985
57pyrimidine-containing compound transmembrane transport (GO:0072531)3.91415700
58GTP biosynthetic process (GO:0006183)3.88655334
59glycerol ether metabolic process (GO:0006662)3.87662204
60phosphatidylethanolamine biosynthetic process (GO:0006646)3.81985566
61cilium morphogenesis (GO:0060271)3.80030692
62meiotic nuclear division (GO:0007126)3.76268542
63seminiferous tubule development (GO:0072520)3.74576198
64establishment or maintenance of monopolar cell polarity (GO:0061339)3.73659830
65establishment of monopolar cell polarity (GO:0061162)3.73659830
66meiosis I (GO:0007127)3.71234732
67spermatid nucleus differentiation (GO:0007289)3.69210998
68cellular component assembly involved in morphogenesis (GO:0010927)3.67897902
69microtubule-based movement (GO:0007018)3.66306358
70ethanol oxidation (GO:0006069)3.63213980
71tolerance induction (GO:0002507)3.62827786
72left/right axis specification (GO:0070986)3.58623710
73phosphatidylethanolamine metabolic process (GO:0046337)3.58333534
74regulation of interleukin-13 production (GO:0032656)3.58123658
75ether metabolic process (GO:0018904)3.56552149
76lateral ventricle development (GO:0021670)3.54239969
77retinoic acid metabolic process (GO:0042573)3.46807373
78negative regulation of B cell mediated immunity (GO:0002713)3.42136049
79negative regulation of immunoglobulin mediated immune response (GO:0002890)3.42136049
80genitalia morphogenesis (GO:0035112)3.38459994
81establishment of tissue polarity (GO:0007164)3.37331648
82establishment of planar polarity (GO:0001736)3.37331648
83terpenoid biosynthetic process (GO:0016114)3.36479359
84UTP biosynthetic process (GO:0006228)3.33917094
85negative regulation of humoral immune response (GO:0002921)3.32828531
86meiotic cell cycle (GO:0051321)3.31030506
87lactate metabolic process (GO:0006089)3.29347929
88cytoplasmic microtubule organization (GO:0031122)3.28031242
89multicellular organismal development (GO:0007275)3.25923748
90microtubule bundle formation (GO:0001578)3.22385093
91protein refolding (GO:0042026)3.19941688
92nonmotile primary cilium assembly (GO:0035058)3.19231333
93chaperone-mediated protein complex assembly (GO:0051131)3.15537694
94determination of left/right symmetry (GO:0007368)3.13048885
95exogenous drug catabolic process (GO:0042738)3.12876863
96response to pheromone (GO:0019236)3.10003156
97UTP metabolic process (GO:0046051)3.05628528
98determination of bilateral symmetry (GO:0009855)2.98233450
99regulation of germinal center formation (GO:0002634)2.92470036
100positive regulation of smoothened signaling pathway (GO:0045880)2.91831992
101oxygen transport (GO:0015671)2.91074582
102specification of symmetry (GO:0009799)2.90643489
103retinal rod cell development (GO:0046548)2.88429678
104negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.86612265
105single strand break repair (GO:0000012)2.84777437
106amino-acid betaine transport (GO:0015838)2.83115592
107carnitine transport (GO:0015879)2.83115592
108organelle assembly (GO:0070925)2.81408845
109glutathione derivative metabolic process (GO:1901685)2.80078533
110glutathione derivative biosynthetic process (GO:1901687)2.80078533
111photoreceptor cell maintenance (GO:0045494)2.78876150
112regulation of cilium assembly (GO:1902017)2.78030669
113microtubule-based process (GO:0007017)2.77387496
114carnitine transmembrane transport (GO:1902603)2.76805954
115calcium ion import (GO:0070509)2.73773631
116protein K11-linked deubiquitination (GO:0035871)2.72584032
117cellular ketone body metabolic process (GO:0046950)2.71258840
118positive regulation of tolerance induction (GO:0002645)2.70190341
119phosphatidylcholine biosynthetic process (GO:0006656)2.69187480
120retinol metabolic process (GO:0042572)2.68628977
121peptidyl-glutamic acid modification (GO:0018200)2.67590746
122guanosine-containing compound biosynthetic process (GO:1901070)2.66811532
123drug catabolic process (GO:0042737)2.64808287
124O-glycan processing (GO:0016266)2.63275452
125establishment of protein localization to Golgi (GO:0072600)2.63173346
126polyol catabolic process (GO:0046174)2.62149939
127primary alcohol metabolic process (GO:0034308)2.61891590
128aldehyde catabolic process (GO:0046185)2.61791326
129excretion (GO:0007588)2.61309643
130negative regulation of organelle assembly (GO:1902116)2.60236002
131chromosome condensation (GO:0030261)2.59708512
132cell projection assembly (GO:0030031)2.59318346
133DNA packaging (GO:0006323)2.57484725
134glycolytic process (GO:0006096)2.57084081
135sexual reproduction (GO:0019953)2.56089446
136monoubiquitinated protein deubiquitination (GO:0035520)2.45366374
137centriole assembly (GO:0098534)2.44501152
138alditol metabolic process (GO:0019400)2.41064817
139CTP metabolic process (GO:0046036)2.39724580
140CTP biosynthetic process (GO:0006241)2.39724580
141cell redox homeostasis (GO:0045454)2.37406901
142synapsis (GO:0007129)2.36170382
143smoothened signaling pathway (GO:0007224)2.35841872
144membrane depolarization during action potential (GO:0086010)2.34664112
145regulation of acrosome reaction (GO:0060046)2.30847745
146regulation of meiosis I (GO:0060631)2.29184258
147cilium or flagellum-dependent cell motility (GO:0001539)13.0102349
148fusion of sperm to egg plasma membrane (GO:0007342)12.2006560
149sperm motility (GO:0030317)11.9682064
150axonemal dynein complex assembly (GO:0070286)11.5017052
151epithelial cilium movement (GO:0003351)10.9770565
152cilium movement (GO:0003341)10.4980565
153acrosome reaction (GO:0007340)10.3067554
154sperm-egg recognition (GO:0035036)10.1048720
155multicellular organism reproduction (GO:0032504)10.0695895
156acrosome assembly (GO:0001675)10.0630337

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse6.31022378
2EZH2_22144423_ChIP-Seq_EOC_Human4.90990045
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.51908637
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.34021740
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.21915255
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.50845058
7PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.46502744
8* FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.11652227
9VDR_22108803_ChIP-Seq_LS180_Human2.10701110
10FLI1_27457419_Chip-Seq_LIVER_Mouse2.01997709
11GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.99362903
12STAT6_21828071_ChIP-Seq_BEAS2B_Human1.95278802
13EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.94952403
14CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.94909405
15FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.89005532
16PCGF2_27294783_Chip-Seq_ESCs_Mouse1.88782825
17ZNF274_21170338_ChIP-Seq_K562_Hela1.80565187
18GATA1_26923725_Chip-Seq_HPCs_Mouse1.77639075
19ARNT_22903824_ChIP-Seq_MCF-7_Human1.73853583
20ELK4_26923725_Chip-Seq_MESODERM_Mouse1.68136716
21PIAS1_25552417_ChIP-Seq_VCAP_Human1.67900931
22NR3C1_21868756_ChIP-Seq_MCF10A_Human1.65425791
23AHR_22903824_ChIP-Seq_MCF-7_Human1.64673060
24CTBP2_25329375_ChIP-Seq_LNCAP_Human1.59692163
25REST_21632747_ChIP-Seq_MESCs_Mouse1.59443251
26MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.58675396
27TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.57171823
28IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.53979489
29CBP_20019798_ChIP-Seq_JUKART_Human1.53979489
30AR_21572438_ChIP-Seq_LNCaP_Human1.52505499
31PCGF2_27294783_Chip-Seq_NPCs_Mouse1.52477989
32ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.52439965
33STAT1_17558387_ChIP-Seq_HELA_Human1.51748772
34CBX2_27304074_Chip-Seq_ESCs_Mouse1.51291227
35* ETV1_20927104_ChIP-Seq_GIST48_Human1.50966949
36TP53_18474530_ChIP-ChIP_U2OS_Human1.49590190
37KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.47567980
38TDRD3_21172665_ChIP-Seq_MCF-7_Human1.46507624
39TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.45060343
40TOP2B_26459242_ChIP-Seq_MCF-7_Human1.45056163
41STAT1_20625510_ChIP-Seq_HELA_Human1.43994757
42* HNFA_21074721_ChIP-Seq_CACO-2_Human1.43965091
43* PHF8_20622853_ChIP-Seq_HELA_Human1.43602220
44SUZ12_27294783_Chip-Seq_NPCs_Mouse1.43434121
45NFE2_27457419_Chip-Seq_LIVER_Mouse1.43144242
46* CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.41912624
47TAL1_26923725_Chip-Seq_HPCs_Mouse1.41777206
48TP63_23658742_ChIP-Seq_EP156T_Human1.40531312
49WDR5_24793694_ChIP-Seq_LNCAP_Human1.39844842
50* RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.38734692
51KDM2B_26808549_Chip-Seq_REH_Human1.38629618
52TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.38235444
53VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.38013153
54STAT3_23295773_ChIP-Seq_U87_Human1.37293289
55* RBPJ_21746931_ChIP-Seq_IB4_Human1.36309578
56SMRT_27268052_Chip-Seq_Bcells_Human1.35244213
57* SMC4_20622854_ChIP-Seq_HELA_Human1.33054785
58ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.32722159
59NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.32412842
60POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.32165686
61TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.32165686
62NANOG_18555785_Chip-Seq_ESCs_Mouse1.32087337
63ZFP57_27257070_Chip-Seq_ESCs_Mouse1.31565521
64ESR1_20079471_ChIP-ChIP_T-47D_Human1.31502843
65* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.31385092
66FUS_26573619_Chip-Seq_HEK293_Human1.30194978
67* PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.30008506
68MYC_19829295_ChIP-Seq_ESCs_Human1.28766901
69* TP63_22573176_ChIP-Seq_HFKS_Human1.28297146
70* CBX2_22325352_ChIP-Seq_293T-Rex_Human1.27717582
71FLI1_21867929_ChIP-Seq_TH2_Mouse1.27663480
72GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.27376377
73* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.27210869
74TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.27092695
75TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.26363202
76* NFYA_21822215_ChIP-Seq_K562_Human1.25511519
77OCT4_20526341_ChIP-Seq_ESCs_Human1.25043114
78* SMAD3_21741376_ChIP-Seq_EPCs_Human1.24803299
79CTCF_20526341_ChIP-Seq_ESCs_Human1.24547178
80EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.24172305
81* TBL1_22424771_ChIP-Seq_293T_Human1.23570724
82RNF2_27304074_Chip-Seq_NSC_Mouse1.23269157
83KAP1_22055183_ChIP-Seq_ESCs_Mouse1.22928642
84KLF5_25053715_ChIP-Seq_YYC3_Human1.21190143
85ZNF217_24962896_ChIP-Seq_MCF-7_Human1.21052279
86* GATA6_21074721_ChIP-Seq_CACO-2_Human1.20762794
87ELF1_20517297_ChIP-Seq_JURKAT_Human1.20671327
88CTCF_27219007_Chip-Seq_Bcells_Human1.20260506
89P53_22387025_ChIP-Seq_ESCs_Mouse1.19847402
90SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.19834623
91NANOG_20526341_ChIP-Seq_ESCs_Human1.19782450
92AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.19173180
93SOX2_22085726_ChIP-Seq_NPCs_Mouse1.18111007
94ERA_21632823_ChIP-Seq_H3396_Human1.18034323
95TAF15_26573619_Chip-Seq_HEK293_Human1.17967891
96RUNX2_22187159_ChIP-Seq_PCA_Human1.17937219
97GF1_26923725_Chip-Seq_HPCs_Mouse1.17805931
98PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.17101422
99CEBPB_22108803_ChIP-Seq_LS180_Human1.17084887
100EZH2_27294783_Chip-Seq_ESCs_Mouse1.16876190
101RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.16705762
102AR_25329375_ChIP-Seq_VCAP_Human1.16559781
103SMAD4_21799915_ChIP-Seq_A2780_Human1.16213370
104DROSHA_22980978_ChIP-Seq_HELA_Human1.16180251
105FOXA1_25329375_ChIP-Seq_VCAP_Human1.15667477
106FOXA1_27270436_Chip-Seq_PROSTATE_Human1.15667477
107* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.15445158
108* SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.15089007
109CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.15056569
110* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.14995099
111CRX_20693478_ChIP-Seq_RETINA_Mouse1.14895010
112YY1_22570637_ChIP-Seq_MALME-3M_Human1.14767895
113GATA3_21878914_ChIP-Seq_MCF-7_Human1.13442053
114PHF8_20622854_ChIP-Seq_HELA_Human1.13278900
115MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.13225887
116* GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.13122083
117GATA3_21867929_ChIP-Seq_CD8_Mouse1.12881539
118* FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.12729074
119FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.12397703
120P300_18555785_Chip-Seq_ESCs_Mouse1.11164437
121EZH2_27294783_Chip-Seq_NPCs_Mouse1.10999895
122SUZ12_27294783_Chip-Seq_ESCs_Mouse1.09389436
123CMYC_18555785_Chip-Seq_ESCs_Mouse1.09348582
124* OCT4_18555785_Chip-Seq_ESCs_Mouse1.08901554
125LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.07999860
126MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.07480406
127RBPJ_22232070_ChIP-Seq_NCS_Mouse1.07404240
128TCF4_22108803_ChIP-Seq_LS180_Human1.07310484
129EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.06321377
130* RUNX1_27514584_Chip-Seq_MCF-7_Human1.05791108
131NCOR_22424771_ChIP-Seq_293T_Human1.05707349
132PRDM14_20953172_ChIP-Seq_ESCs_Human1.05392852
133STAT3_18555785_Chip-Seq_ESCs_Mouse1.05363028
134OCT4_21477851_ChIP-Seq_ESCs_Mouse1.05352902
135SUZ12_18555785_Chip-Seq_ESCs_Mouse1.04391649
136KLF4_18555785_Chip-Seq_ESCs_Mouse1.04227900
137GATA3_21867929_ChIP-Seq_TH1_Mouse1.04207075
138CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.03667629
139E2F1_20622854_ChIP-Seq_HELA_Human1.03660454
140ESRRB_18555785_Chip-Seq_ESCs_Mouse1.03427987
141* TCF4_23295773_ChIP-Seq_U87_Human1.02971371
142TAF2_19829295_ChIP-Seq_ESCs_Human1.02810372
143ERG_20517297_ChIP-Seq_VCAP_Human1.02537387
144SMAD4_21741376_ChIP-Seq_HESCs_Human1.02326497
145SOX2_18555785_Chip-Seq_ESCs_Mouse1.02322644
146SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.01941833
147* CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01913193
148RAD21_21589869_ChIP-Seq_MESCs_Mouse1.01841892
149SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.01591704
150* P53_21459846_ChIP-Seq_SAOS-2_Human1.01223754
151P300_27268052_Chip-Seq_Bcells_Human1.00801555
152PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.99506547
153P68_20966046_ChIP-Seq_HELA_Human0.99425740
154KLF5_20875108_ChIP-Seq_MESCs_Mouse0.99400230
155BCAT_22108803_ChIP-Seq_LS180_Human0.98888829
156RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.98432844
157* SMAD4_21741376_ChIP-Seq_EPCs_Human0.98243652
158ER_23166858_ChIP-Seq_MCF-7_Human0.97607779
159CTBP1_25329375_ChIP-Seq_LNCAP_Human0.97450750
160PU1_27457419_Chip-Seq_LIVER_Mouse0.97072563
161AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.96793507
162EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.96065946
163E2F1_18555785_Chip-Seq_ESCs_Mouse0.95201821
164PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.94743878
165CTCF_18555785_Chip-Seq_ESCs_Mouse0.94478230
166ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.94172028
167EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.94018279
168* NFYB_21822215_ChIP-Seq_K562_Human0.93748258
169GF1B_26923725_Chip-Seq_HPCs_Mouse0.93694042
170ZFX_18555785_Chip-Seq_ESCs_Mouse0.93586727
171* RUNX1_26923725_Chip-Seq_HPCs_Mouse0.93570736

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.31636459
2MP0001929_abnormal_gametogenesis4.73047252
3MP0002132_abnormal_respiratory_system4.16094272
4MP0008877_abnormal_DNA_methylation3.48963825
5MP0002653_abnormal_ependyma_morphology3.34891072
6MP0002210_abnormal_sex_determination2.91402706
7MP0002254_reproductive_system_inflammat2.86023530
8MP0002161_abnormal_fertility/fecundity2.83823974
9MP0008789_abnormal_olfactory_epithelium2.77005468
10MP0000566_synostosis2.44897462
11MP0001145_abnormal_male_reproductive2.40375652
12MP0002277_abnormal_respiratory_mucosa2.39825487
13MP0005645_abnormal_hypothalamus_physiol2.36872455
14MP0001984_abnormal_olfaction2.32038393
15MP0005670_abnormal_white_adipose2.20709413
16MP0000653_abnormal_sex_gland2.11457121
17MP0002160_abnormal_reproductive_system2.09354325
18MP0000383_abnormal_hair_follicle2.00746572
19MP0005410_abnormal_fertilization14.0891178
20MP0005623_abnormal_meninges_morphology1.98621257
21MP0002876_abnormal_thyroid_physiology1.86548439
22MP0005499_abnormal_olfactory_system1.85793695
23MP0005394_taste/olfaction_phenotype1.85793695
24MP0002168_other_aberrant_phenotype1.84041534
25MP0000678_abnormal_parathyroid_gland1.81168696
26MP0002282_abnormal_trachea_morphology1.60276341
27MP0004019_abnormal_vitamin_homeostasis1.55003603
28MP0009046_muscle_twitch1.53635973
29MP0010678_abnormal_skin_adnexa1.53295951
30MP0002249_abnormal_larynx_morphology1.49710682
31MP0005395_other_phenotype1.48581853
32MP0001765_abnormal_ion_homeostasis1.41808027
33MP0003879_abnormal_hair_cell1.40365560
34MP0005647_abnormal_sex_gland1.38513822
35MP0005083_abnormal_biliary_tract1.37956855
36MP0003183_abnormal_peptide_metabolism1.31402045
37MP0001348_abnormal_lacrimal_gland1.31158901
38MP0002909_abnormal_adrenal_gland1.24405158
39MP0000026_abnormal_inner_ear1.19236382
40MP0002928_abnormal_bile_duct1.16595184
41MP0003718_maternal_effect1.12432678
42MP0005377_hearing/vestibular/ear_phenot1.11607501
43MP0003878_abnormal_ear_physiology1.11607501
44MP0005389_reproductive_system_phenotype1.10516576
45MP0005646_abnormal_pituitary_gland1.07457434
46MP0000681_abnormal_thyroid_gland1.02188639
47MP0003656_abnormal_erythrocyte_physiolo1.00298091
48MP0001346_abnormal_lacrimal_gland0.99182579
49MP0008995_early_reproductive_senescence0.98125541
50MP0002693_abnormal_pancreas_physiology0.97388540
51MP0001501_abnormal_sleep_pattern0.96392302
52MP0005248_abnormal_Harderian_gland0.94521839
53MP0003646_muscle_fatigue0.91005512
54MP0001293_anophthalmia0.90490019
55MP0000049_abnormal_middle_ear0.90297339
56MP0001486_abnormal_startle_reflex0.86427907
57MP0003950_abnormal_plasma_membrane0.86034827
58MP0001440_abnormal_grooming_behavior0.84867237
59MP0001970_abnormal_pain_threshold0.82655547
60MP0002233_abnormal_nose_morphology0.82307835
61MP0005195_abnormal_posterior_eye0.79975618
62MP0001764_abnormal_homeostasis0.79586734
63MP0003136_yellow_coat_color0.79074030
64MP0000013_abnormal_adipose_tissue0.78035840
65MP0001944_abnormal_pancreas_morphology0.75973244
66MP0001502_abnormal_circadian_rhythm0.75964783
67MP0005085_abnormal_gallbladder_physiolo0.73650730
68MP0001324_abnormal_eye_pigmentation0.71610778
69MP0000955_abnormal_spinal_cord0.70583287
70MP0003329_amyloid_beta_deposits0.70065984
71MP0005310_abnormal_salivary_gland0.68739280
72MP0001905_abnormal_dopamine_level0.68696397
73MP0002638_abnormal_pupillary_reflex0.68219409
74MP0003937_abnormal_limbs/digits/tail_de0.68060201
75MP0005636_abnormal_mineral_homeostasis0.66882218
76MP0005551_abnormal_eye_electrophysiolog0.65539474
77MP0001299_abnormal_eye_distance/0.64835959
78MP0010030_abnormal_orbit_morphology0.64793267
79MP0010386_abnormal_urinary_bladder0.64779473
80MP0008872_abnormal_physiological_respon0.64577965
81MP0002572_abnormal_emotion/affect_behav0.64196066
82MP0005253_abnormal_eye_physiology0.63482446
83MP0004233_abnormal_muscle_weight0.63200476
84MP0005379_endocrine/exocrine_gland_phen0.63073080
85MP0002557_abnormal_social/conspecific_i0.62497703
86MP0002734_abnormal_mechanical_nocicepti0.61333397
87MP0005365_abnormal_bile_salt0.60638370
88MP0006072_abnormal_retinal_apoptosis0.60497138
89MP0003045_fibrosis0.59870305
90MP0002136_abnormal_kidney_physiology0.59489969
91MP0001664_abnormal_digestion0.59430007
92MP0006276_abnormal_autonomic_nervous0.58890558
93MP0002822_catalepsy0.58494455
94MP0002735_abnormal_chemical_nociception0.57866806
95MP0003959_abnormal_lean_body0.56852672
96MP0009643_abnormal_urine_homeostasis0.56614249
97MP0001270_distended_abdomen0.56572922
98MP0004043_abnormal_pH_regulation0.55895320
99MP0000003_abnormal_adipose_tissue0.54864618
100MP0005535_abnormal_body_temperature0.53796048
101MP0008961_abnormal_basal_metabolism0.53770340
102MP0002971_abnormal_brown_adipose0.53649337
103MP0002102_abnormal_ear_morphology0.52585606
104MP0002067_abnormal_sensory_capabilities0.52005098
105MP0001873_stomach_inflammation0.51919082
106MP0004742_abnormal_vestibular_system0.51763189
107MP0002736_abnormal_nociception_after0.50883350
108MP0004085_abnormal_heartbeat0.50807634
109MP0002234_abnormal_pharynx_morphology0.50675330
110MP0002877_abnormal_melanocyte_morpholog0.50060634
111MP0002116_abnormal_craniofacial_bone0.49759159
112MP0002752_abnormal_somatic_nervous0.49377171
113MP0002272_abnormal_nervous_system0.48663694
114MP0005164_abnormal_response_to0.48612280
115MP0004270_analgesia0.48585117
116MP0000534_abnormal_ureter_morphology0.48479978
117MP0009115_abnormal_fat_cell0.47565582
118MP0001851_eye_inflammation0.47490485
119MP0004858_abnormal_nervous_system0.47362764
120MP0003635_abnormal_synaptic_transmissio0.46734216
121MP0001968_abnormal_touch/_nociception0.46288353
122MP0008875_abnormal_xenobiotic_pharmacok0.44625641
123MP0008004_abnormal_stomach_pH0.44407380
124MP0003283_abnormal_digestive_organ0.44305782
125MP0002063_abnormal_learning/memory/cond0.44095669
126MP0003953_abnormal_hormone_level0.43373897
127MP0001485_abnormal_pinna_reflex0.42362345
128MP0002064_seizures0.41541571
129MP0002078_abnormal_glucose_homeostasis0.41374546
130MP0004134_abnormal_chest_morphology0.39667230
131MP0002139_abnormal_hepatobiliary_system0.38487378
132MP0003195_calcinosis0.38459341
133MP0001963_abnormal_hearing_physiology0.38243170
134MP0000685_abnormal_immune_system0.37920629
135MP0003633_abnormal_nervous_system0.37713204
136MP0006082_CNS_inflammation0.37688933
137MP0002295_abnormal_pulmonary_circulatio0.35989705
138MP0004133_heterotaxia0.35656974
139MP0009745_abnormal_behavioral_response0.35391768
140MP0000631_abnormal_neuroendocrine_gland0.35062226
141MP0003699_abnormal_female_reproductive0.34403990
142MP0002837_dystrophic_cardiac_calcinosis0.33080069
143MP0000604_amyloidosis0.33002336
144MP0002229_neurodegeneration0.32702186
145MP0009780_abnormal_chondrocyte_physiolo0.32648712
146MP0005391_vision/eye_phenotype0.32380009

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.96291913
2Abnormal respiratory epithelium morphology (HP:0012253)8.95310725
3Abnormal respiratory motile cilium morphology (HP:0005938)8.95310725
4Abnormal ciliary motility (HP:0012262)8.66952698
5Rhinitis (HP:0012384)8.28062466
6Chronic bronchitis (HP:0004469)7.56682574
7Nasal polyposis (HP:0100582)5.91931153
8Infertility (HP:0000789)5.52302559
9Bronchiectasis (HP:0002110)4.99856529
10Abnormality of the nasal mucosa (HP:0000433)4.86561303
11Nephronophthisis (HP:0000090)4.48544527
12Bronchitis (HP:0012387)4.44623310
13Abnormality of the renal medulla (HP:0100957)3.41780903
14Male infertility (HP:0003251)3.28389558
15Recurrent sinusitis (HP:0011108)3.24014328
16Abnormality of midbrain morphology (HP:0002418)3.19568137
17Molar tooth sign on MRI (HP:0002419)3.19568137
18Tubulointerstitial nephritis (HP:0001970)3.13958861
19Recurrent otitis media (HP:0000403)3.04222398
20Medial flaring of the eyebrow (HP:0010747)3.04182032
21Tubular atrophy (HP:0000092)2.72188327
22Atelectasis (HP:0100750)2.69960800
23Pancreatic fibrosis (HP:0100732)2.54899070
24Chronic otitis media (HP:0000389)2.53103057
25Tubulointerstitial abnormality (HP:0001969)2.51986331
26Hyperactive renin-angiotensin system (HP:0000841)2.50937267
27Anencephaly (HP:0002323)2.42162215
28Abnormal spermatogenesis (HP:0008669)2.37901166
29Recurrent bronchitis (HP:0002837)2.36583800
30True hermaphroditism (HP:0010459)2.36560541
31Fibular hypoplasia (HP:0003038)2.36343185
32Congenital hepatic fibrosis (HP:0002612)2.30276385
33Chronic sinusitis (HP:0011109)2.27758705
34Postaxial foot polydactyly (HP:0001830)2.24776222
35Cystic liver disease (HP:0006706)2.18163449
36Sclerocornea (HP:0000647)2.14972416
37Male pseudohermaphroditism (HP:0000037)2.13170755
38Median cleft lip (HP:0000161)2.11049701
39Gait imbalance (HP:0002141)2.10949301
40Congenital primary aphakia (HP:0007707)2.10857118
41Polydipsia (HP:0001959)2.05146079
42Abnormal drinking behavior (HP:0030082)2.05146079
43Tubulointerstitial fibrosis (HP:0005576)2.04285276
44Stage 5 chronic kidney disease (HP:0003774)2.00259217
45Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.0110703
46Dynein arm defect of respiratory motile cilia (HP:0012255)11.6229212
47Absent/shortened dynein arms (HP:0200106)11.6229212
48Decreased circulating renin level (HP:0003351)1.98535512
49Abnormality of dentin (HP:0010299)1.90099363
50Abnormality of the renal cortex (HP:0011035)1.85241827
51Bile duct proliferation (HP:0001408)1.82312007
52Abnormal biliary tract physiology (HP:0012439)1.82312007
53Furrowed tongue (HP:0000221)1.82258438
54Postaxial hand polydactyly (HP:0001162)1.82188396
55Chronic hepatic failure (HP:0100626)1.81485797
56Nephrogenic diabetes insipidus (HP:0009806)1.80313611
57Aplasia/Hypoplasia of the lens (HP:0008063)1.79463096
58Oculomotor apraxia (HP:0000657)1.77136051
59Taurodontia (HP:0000679)1.75215887
60Abnormality of permanent molar morphology (HP:0011071)1.75215887
61Abnormality of the dental root (HP:0006486)1.75215887
62Aplasia/Hypoplasia of the spleen (HP:0010451)1.74895204
63Bell-shaped thorax (HP:0001591)1.73413750
64Abnormal rod and cone electroretinograms (HP:0008323)1.72707400
65Aplasia/Hypoplasia of the tongue (HP:0010295)1.71912417
66Azoospermia (HP:0000027)1.70927249
67Pancreatic cysts (HP:0001737)1.69767381
68Occipital encephalocele (HP:0002085)1.69515989
69Gonadotropin excess (HP:0000837)1.68347727
70Asplenia (HP:0001746)1.67217906
71Facial cleft (HP:0002006)1.65919169
72Renal salt wasting (HP:0000127)1.65615966
73Genital tract atresia (HP:0001827)1.64699287
74Abnormality of the dental pulp (HP:0006479)1.64411896
75Neurofibrillary tangles (HP:0002185)1.62951655
76Abnormality of renal excretion (HP:0011036)1.62573497
77Abnormality of molar morphology (HP:0011070)1.60405687
78Abnormality of molar (HP:0011077)1.60405687
79Cone-rod dystrophy (HP:0000548)1.59443142
80Hypoplasia of the capital femoral epiphysis (HP:0003090)1.59364394
81Decreased central vision (HP:0007663)1.59224478
82Absent rod-and cone-mediated responses on ERG (HP:0007688)1.58845371
83Abnormal gallbladder physiology (HP:0012438)1.58341475
84Cholecystitis (HP:0001082)1.58341475
85Impulsivity (HP:0100710)1.57046511
86Abnormality of macular pigmentation (HP:0008002)1.56960807
87Hyperkalemia (HP:0002153)1.56859093
88Nephropathy (HP:0000112)1.56494514
89Preaxial hand polydactyly (HP:0001177)1.56470736
90Vaginal atresia (HP:0000148)1.56156619
91Short ribs (HP:0000773)1.51008666
92Poor coordination (HP:0002370)1.50645299
93Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.50578261
94Absent epiphyses (HP:0010577)1.50578261
95Severe visual impairment (HP:0001141)1.50134321
96Bony spicule pigmentary retinopathy (HP:0007737)1.49599824
97Aplasia/Hypoplasia of the fibula (HP:0006492)1.47566760
98Hyperaldosteronism (HP:0000859)1.45719022
99Abnormality of chloride homeostasis (HP:0011422)1.45155462
100Short thorax (HP:0010306)1.44735600
101Short nail (HP:0001799)1.41974339
102Hypoplasia of dental enamel (HP:0006297)1.40679121
103Abnormal urine output (HP:0012590)1.38741363
104Renal dysplasia (HP:0000110)1.38303061
105J-shaped sella turcica (HP:0002680)1.38130480
106Abnormality of renin-angiotensin system (HP:0000847)1.37934107
107Hemiparesis (HP:0001269)1.33543207
108Abnormality of the lower motor neuron (HP:0002366)1.30901999
109Supernumerary spleens (HP:0009799)1.30524677
110Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.29313534
111Congenital malformation of the right heart (HP:0011723)1.27918490
112Double outlet right ventricle (HP:0001719)1.27918490
11311 pairs of ribs (HP:0000878)1.26797600
114Absent frontal sinuses (HP:0002688)1.26284665
115Dyschromatopsia (HP:0007641)1.26180202
116Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.23758166
117Polyuria (HP:0000103)1.23669253
118Abnormality of calcium-phosphate metabolism (HP:0100530)1.23641629
119Microglossia (HP:0000171)1.23206441
120Cerebral inclusion bodies (HP:0100314)1.20792441
121Retinal atrophy (HP:0001105)1.20762870
122Broad distal phalanx of finger (HP:0009836)1.19570062
123Hypokalemic alkalosis (HP:0001949)1.18583844
124Retinitis pigmentosa (HP:0000510)1.18414452
125Portal hypertension (HP:0001409)1.12631146
126Hyponatremia (HP:0002902)1.12576372
127Attenuation of retinal blood vessels (HP:0007843)1.10670417
128Prominent nasal bridge (HP:0000426)1.09878001
129Multicystic kidney dysplasia (HP:0000003)1.09562423
130Narrow forehead (HP:0000341)1.08801782
131Aganglionic megacolon (HP:0002251)1.08622066
132Intellectual disability, moderate (HP:0002342)1.05905376
133Short femoral neck (HP:0100864)1.04731740
134Holoprosencephaly (HP:0001360)1.04687804

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK47.11653436
2PDK37.11653436
3TESK15.39135272
4PRKD35.30763849
5PDK24.54201968
6ICK4.02659662
7MAPK153.92099813
8PNCK3.54920432
9WNK42.56364634
10PTK2B2.45760956
11PLK42.39172766
12MAPKAPK32.04224863
13STK391.93174033
14TLK11.83504475
15MAP4K21.82457319
16DYRK1B1.76855268
17IRAK11.53827351
18STK381.45129713
19MST1R1.43852418
20DYRK31.17036148
21STK161.10865838
22DDR21.09322666
23BCR1.07636856
24NTRK21.03687939
25EEF2K0.98732864
26WNK10.97288984
27STK240.90700389
28MAP3K70.88212738
29PDK10.84514885
30TTK0.84139461
31PASK0.81956823
32CAMK1G0.79827417
33INSRR0.77945320
34TYRO30.76898319
35PRKCI0.68253736
36TRPM70.66162131
37CSK0.65342333
38BCKDK0.63998236
39IRAK20.62207611
40STK38L0.61305620
41STK30.60192727
42NEK20.59017890
43PRKCG0.57836392
44BMPR1B0.56921193
45OXSR10.54711518
46LMTK20.54496239
47AKT30.54243158
48MET0.51357995
49MAP3K20.50119898
50NME10.49632158
51CDK30.49310095
52PDPK10.47783790
53MAPK130.45733035
54CAMKK20.45312438
55NLK0.45283082
56MAP2K60.44471088
57MAP2K20.44183723
58MAP3K30.40728221
59BRD40.40348205
60ADRBK10.39858193
61FRK0.39197495
62ERBB20.38969820
63ROCK10.37277458
64NEK60.37134249
65TIE10.36328506
66ACVR1B0.35870572
67CAMKK10.35756436
68PINK10.35182968
69PRKCE0.34537155
70CDC42BPA0.33917609
71MAPKAPK50.32302269
72PAK20.32224901
73DYRK1A0.31700893
74ZAK0.31500488
75MAP3K40.31147682
76IRAK30.31074221
77MARK20.30738391
78STK100.30687794
79SGK10.30171107
80PIK3CG0.29482760
81TAOK20.28925642
82WNK30.27904955
83AURKA0.27770296
84PRKG20.27662957
85GRK10.26657655
86MST40.26635948
87DAPK20.25807793
88SIK20.24918656
89EPHA40.24400717
90PLK10.24209549
91GRK50.24145434
92BRAF0.23988213
93MAP2K70.23757579
94PRKCZ0.23626930
95RIPK40.23507736
96RPS6KB10.23101808
97TNIK0.22608088
98CAMK2A0.22088140
99PRKCD0.22083337
100PRKAA10.21710281
101MAP3K10.21671909
102LATS10.21492880
103PKN10.21424748
104SMG10.21343021
105RPS6KA20.21250030
106STK110.21122409
107ADRBK20.20647155
108GSK3A0.20625318
109ATM0.19894649
110BRSK20.19726622
111MTOR0.19453174
112PRKG10.18831375
113CAMK2G0.18654087
114PRKCQ0.18353248
115ERBB30.18220060
116CHEK20.17231714
117BMPR20.16355943
118CHUK0.16238375
119CAMK10.15797279
120PAK10.15651621
121ABL10.15542412
122LRRK20.15524795
123TBK10.14922055
124MAP2K10.14764256
125TAOK30.14436385
126PRKACG0.14161281
127TGFBR10.14070927
128FER0.13551768
129CHEK10.13106678
130EPHB10.12598562
131PRKCA0.12330788
132PRKAA20.12157176
133PRKACA0.11580217
134PRKDC0.11319569
135MUSK0.11170878
136NTRK30.10864043
137GSK3B0.10462062
138ARAF0.09795318
139EPHA30.09688681
140PTK60.09635452
141PLK20.09337293
142EPHA20.09312543
143EGFR0.08108329
144SGK20.07512117
145MARK10.07254085

Predicted pathways (KEGG)

RankGene SetZ-score
1Phenylalanine metabolism_Homo sapiens_hsa003604.03686788
2Tyrosine metabolism_Homo sapiens_hsa003503.18959473
3Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.02252082
4Fatty acid biosynthesis_Homo sapiens_hsa000613.00690490
5Pyruvate metabolism_Homo sapiens_hsa006202.78632658
6Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.70828872
7beta-Alanine metabolism_Homo sapiens_hsa004102.69193438
8Vitamin B6 metabolism_Homo sapiens_hsa007502.49496330
9Glucagon signaling pathway_Homo sapiens_hsa049222.38372687
10alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.35597073
11Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.33105453
12Linoleic acid metabolism_Homo sapiens_hsa005912.32067447
13Amphetamine addiction_Homo sapiens_hsa050312.29949885
14Maturity onset diabetes of the young_Homo sapiens_hsa049502.23209595
15Retinol metabolism_Homo sapiens_hsa008302.13466448
16Dorso-ventral axis formation_Homo sapiens_hsa043202.09672623
17Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.98541634
18Insulin secretion_Homo sapiens_hsa049111.95474320
19Caffeine metabolism_Homo sapiens_hsa002321.93648724
20Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.90960181
21Olfactory transduction_Homo sapiens_hsa047401.90180735
22Glycosaminoglycan degradation_Homo sapiens_hsa005311.87590219
23Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.84542067
24Carbohydrate digestion and absorption_Homo sapiens_hsa049731.84499916
25Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.79366569
26Propanoate metabolism_Homo sapiens_hsa006401.77943831
27Huntingtons disease_Homo sapiens_hsa050161.65847257
28Steroid hormone biosynthesis_Homo sapiens_hsa001401.63656968
29Phototransduction_Homo sapiens_hsa047441.61876913
30Butanoate metabolism_Homo sapiens_hsa006501.57620842
31Taste transduction_Homo sapiens_hsa047421.54907497
32Selenocompound metabolism_Homo sapiens_hsa004501.52577506
33PPAR signaling pathway_Homo sapiens_hsa033201.52165408
34Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.49452808
35Collecting duct acid secretion_Homo sapiens_hsa049661.45662768
36Glycerophospholipid metabolism_Homo sapiens_hsa005641.42996056
37Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.42898232
38Antigen processing and presentation_Homo sapiens_hsa046121.37936288
39Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.37240203
40Ether lipid metabolism_Homo sapiens_hsa005651.36910684
41Renin secretion_Homo sapiens_hsa049241.35801596
42Glycerolipid metabolism_Homo sapiens_hsa005611.30669177
43Basal transcription factors_Homo sapiens_hsa030221.25311505
44Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.23785475
45Mineral absorption_Homo sapiens_hsa049781.23707953
46Circadian entrainment_Homo sapiens_hsa047131.22472044
47Peroxisome_Homo sapiens_hsa041461.20953633
48Fructose and mannose metabolism_Homo sapiens_hsa000511.19991750
49Primary bile acid biosynthesis_Homo sapiens_hsa001201.19579616
50Synaptic vesicle cycle_Homo sapiens_hsa047211.17672045
51Histidine metabolism_Homo sapiens_hsa003401.16193980
52Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.15290024
53Cardiac muscle contraction_Homo sapiens_hsa042601.15257666
54Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.14326058
55Sulfur metabolism_Homo sapiens_hsa009201.13749057
56Thyroid hormone synthesis_Homo sapiens_hsa049181.13367815
57Tight junction_Homo sapiens_hsa045301.10561532
58Protein export_Homo sapiens_hsa030601.08204475
59Cocaine addiction_Homo sapiens_hsa050301.06493084
60Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.04307613
61Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.03252425
62Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.02431417
63Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.00819156
64ABC transporters_Homo sapiens_hsa020100.98227695
65Long-term potentiation_Homo sapiens_hsa047200.98162875
66Pentose phosphate pathway_Homo sapiens_hsa000300.95354954
67Nicotine addiction_Homo sapiens_hsa050330.93700005
68Calcium signaling pathway_Homo sapiens_hsa040200.91048292
69Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.89637474
70Estrogen signaling pathway_Homo sapiens_hsa049150.89211138
71Oocyte meiosis_Homo sapiens_hsa041140.88888219
72Gastric acid secretion_Homo sapiens_hsa049710.88305429
73Salivary secretion_Homo sapiens_hsa049700.88035376
74Vibrio cholerae infection_Homo sapiens_hsa051100.85398717
75Nitrogen metabolism_Homo sapiens_hsa009100.85198542
76Arachidonic acid metabolism_Homo sapiens_hsa005900.84238351
77Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.83955638
78Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.81837497
79Glutamatergic synapse_Homo sapiens_hsa047240.76797649
80cGMP-PKG signaling pathway_Homo sapiens_hsa040220.76389539
81Starch and sucrose metabolism_Homo sapiens_hsa005000.73188111
82Fat digestion and absorption_Homo sapiens_hsa049750.72534727
83Sphingolipid metabolism_Homo sapiens_hsa006000.69996009
84Chemical carcinogenesis_Homo sapiens_hsa052040.69235982
85cAMP signaling pathway_Homo sapiens_hsa040240.69117014
86Fatty acid degradation_Homo sapiens_hsa000710.68609568
87Phosphatidylinositol signaling system_Homo sapiens_hsa040700.67664595
88Bile secretion_Homo sapiens_hsa049760.67137346
89Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.66747261
90Fatty acid metabolism_Homo sapiens_hsa012120.66127890
91Hedgehog signaling pathway_Homo sapiens_hsa043400.65867371
92Morphine addiction_Homo sapiens_hsa050320.65269916
93Type II diabetes mellitus_Homo sapiens_hsa049300.64015497
94Pentose and glucuronate interconversions_Homo sapiens_hsa000400.63375337
95Dopaminergic synapse_Homo sapiens_hsa047280.61814656
96Pancreatic secretion_Homo sapiens_hsa049720.59774230
97Vascular smooth muscle contraction_Homo sapiens_hsa042700.57137580
98Adipocytokine signaling pathway_Homo sapiens_hsa049200.56590964
99Protein digestion and absorption_Homo sapiens_hsa049740.54272960
100Inositol phosphate metabolism_Homo sapiens_hsa005620.53434631
101Arginine and proline metabolism_Homo sapiens_hsa003300.52681380
102Aldosterone synthesis and secretion_Homo sapiens_hsa049250.51059637
103Cysteine and methionine metabolism_Homo sapiens_hsa002700.50106765
104GABAergic synapse_Homo sapiens_hsa047270.48458723
105Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.47151613
106Basal cell carcinoma_Homo sapiens_hsa052170.45706484
107Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.45309555
108Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.42712521
109Drug metabolism - other enzymes_Homo sapiens_hsa009830.42605607
110Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.40194767
111Renin-angiotensin system_Homo sapiens_hsa046140.39835043
112Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.39068729
113Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.38567115
114Type I diabetes mellitus_Homo sapiens_hsa049400.38328989
115Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.37916155
116Circadian rhythm_Homo sapiens_hsa047100.37447816
117Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.37080744
118Glutathione metabolism_Homo sapiens_hsa004800.36661439
119Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.35755380
120Purine metabolism_Homo sapiens_hsa002300.34815724
121Carbon metabolism_Homo sapiens_hsa012000.33579901
122Choline metabolism in cancer_Homo sapiens_hsa052310.33360666
123N-Glycan biosynthesis_Homo sapiens_hsa005100.31399910
124Serotonergic synapse_Homo sapiens_hsa047260.31120108
125AMPK signaling pathway_Homo sapiens_hsa041520.30804062
126Phagosome_Homo sapiens_hsa041450.30572528
127Notch signaling pathway_Homo sapiens_hsa043300.30282620
128Metabolic pathways_Homo sapiens_hsa011000.29493743
129Ovarian steroidogenesis_Homo sapiens_hsa049130.28027802
130Tryptophan metabolism_Homo sapiens_hsa003800.27717494
131Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.22356071
132Transcriptional misregulation in cancer_Homo sapiens_hsa052020.21540818
133Hippo signaling pathway_Homo sapiens_hsa043900.19632182
134Intestinal immune network for IgA production_Homo sapiens_hsa046720.19088970
135Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.19001296
136Arginine biosynthesis_Homo sapiens_hsa002200.18614330
137Graft-versus-host disease_Homo sapiens_hsa053320.18344901
138Autoimmune thyroid disease_Homo sapiens_hsa053200.17853407
139Adherens junction_Homo sapiens_hsa045200.17241878
140Allograft rejection_Homo sapiens_hsa053300.14939254

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