Rank | Gene Set | Z-score |
---|---|---|
1 | negative regulation of B cell apoptotic process (GO:0002903) | 4.95713511 |
2 | apoptotic cell clearance (GO:0043277) | 4.58306873 |
3 | response to peptidoglycan (GO:0032494) | 4.30473228 |
4 | immunoglobulin mediated immune response (GO:0016064) | 4.18829686 |
5 | T cell apoptotic process (GO:0070231) | 4.14664344 |
6 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 4.10766799 |
7 | negative regulation of T-helper cell differentiation (GO:0045623) | 4.01580786 |
8 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 4.01580786 |
9 | regulation of B cell apoptotic process (GO:0002902) | 3.63907250 |
10 | B cell mediated immunity (GO:0019724) | 3.62988584 |
11 | NLS-bearing protein import into nucleus (GO:0006607) | 3.50726659 |
12 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.46801877 |
13 | lymphocyte apoptotic process (GO:0070227) | 3.45767473 |
14 | regulation of mitotic spindle organization (GO:0060236) | 3.43733549 |
15 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.41007649 |
16 | regulation of cholesterol storage (GO:0010885) | 3.40115280 |
17 | germinal center formation (GO:0002467) | 3.27412247 |
18 | positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:0061081 | 3.27409328 |
19 | endothelial tube morphogenesis (GO:0061154) | 3.20163386 |
20 | morphogenesis of an endothelium (GO:0003159) | 3.20163386 |
21 | response to muramyl dipeptide (GO:0032495) | 3.19676276 |
22 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 3.19408052 |
23 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.13175749 |
24 | muscle filament sliding (GO:0030049) | 3.12632503 |
25 | actin-myosin filament sliding (GO:0033275) | 3.12632503 |
26 | barbed-end actin filament capping (GO:0051016) | 3.12237843 |
27 | protein localization to endosome (GO:0036010) | 3.10146984 |
28 | positive regulation of triglyceride biosynthetic process (GO:0010867) | 3.07176710 |
29 | neutrophil activation involved in immune response (GO:0002283) | 3.05848003 |
30 | stress fiber assembly (GO:0043149) | 3.05775851 |
31 | skeletal muscle contraction (GO:0003009) | 3.04547093 |
32 | negative regulation of stress fiber assembly (GO:0051497) | 3.00475721 |
33 | positive regulation of cholesterol efflux (GO:0010875) | 2.99958940 |
34 | negative regulation of cell size (GO:0045792) | 2.95562591 |
35 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.94348866 |
36 | regulation of cholesterol homeostasis (GO:2000188) | 2.93070404 |
37 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.93018053 |
38 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 2.92112262 |
39 | regulation of gamma-delta T cell activation (GO:0046643) | 2.90525617 |
40 | cellular extravasation (GO:0045123) | 2.88612772 |
41 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.86936211 |
42 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 2.85554298 |
43 | respiratory tube development (GO:0030323) | 2.84738739 |
44 | focal adhesion assembly (GO:0048041) | 2.84069790 |
45 | cell-substrate adherens junction assembly (GO:0007045) | 2.84069790 |
46 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.81680345 |
47 | negative regulation of cell killing (GO:0031342) | 2.81680345 |
48 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 2.81392403 |
49 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 2.79997006 |
50 | cellular response to thyroid hormone stimulus (GO:0097067) | 2.79925901 |
51 | NIK/NF-kappaB signaling (GO:0038061) | 2.78860674 |
52 | regulation of mast cell degranulation (GO:0043304) | 2.78249148 |
53 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.77903218 |
54 | negative regulation of granulocyte differentiation (GO:0030853) | 2.77498689 |
55 | lung vasculature development (GO:0060426) | 2.77449783 |
56 | macrophage activation involved in immune response (GO:0002281) | 2.76695471 |
57 | regulation of leukocyte degranulation (GO:0043300) | 2.74320655 |
58 | modulation by symbiont of host cellular process (GO:0044068) | 2.69838024 |
59 | pentose-phosphate shunt (GO:0006098) | 2.66039063 |
60 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 2.65706858 |
61 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.65599720 |
62 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.65599720 |
63 | modulation by symbiont of host immune response (GO:0052553) | 2.65599720 |
64 | positive regulation by symbiont of host defense response (GO:0052509) | 2.65599720 |
65 | modulation by symbiont of host defense response (GO:0052031) | 2.65599720 |
66 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.65599720 |
67 | positive regulation of histone deacetylation (GO:0031065) | 2.64807675 |
68 | positive regulation of cholesterol transport (GO:0032376) | 2.64676302 |
69 | positive regulation of sterol transport (GO:0032373) | 2.64676302 |
70 | regulation of early endosome to late endosome transport (GO:2000641) | 2.64472566 |
71 | regulation of skeletal muscle contraction (GO:0014819) | 2.61936966 |
72 | regulation of histone H3-K27 methylation (GO:0061085) | 2.60476520 |
73 | leukocyte apoptotic process (GO:0071887) | 2.59510092 |
74 | negative regulation of type 2 immune response (GO:0002829) | 2.58580058 |
75 | positive regulation of myotube differentiation (GO:0010831) | 2.58524819 |
76 | response to laminar fluid shear stress (GO:0034616) | 2.57525213 |
77 | substrate-dependent cell migration (GO:0006929) | 2.56735223 |
78 | negative regulation of necroptotic process (GO:0060546) | 2.56495222 |
79 | regulation of necroptotic process (GO:0060544) | 2.56259249 |
80 | negative regulation of phagocytosis (GO:0050765) | 2.55111154 |
81 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.53859715 |
82 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.53859715 |
83 | negative regulation of interleukin-12 production (GO:0032695) | 2.53617955 |
84 | basement membrane organization (GO:0071711) | 2.53553241 |
85 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.53134623 |
86 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.52784969 |
87 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 2.52365798 |
88 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 2.52025833 |
89 | cell adhesion mediated by integrin (GO:0033627) | 2.51907414 |
90 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.51721552 |
91 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.51077503 |
92 | glycosphingolipid catabolic process (GO:0046479) | 2.50307937 |
93 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 2.49695537 |
94 | negative regulation of innate immune response (GO:0045824) | 2.49175942 |
95 | regulation of integrin activation (GO:0033623) | 2.47202864 |
96 | positive regulation of B cell differentiation (GO:0045579) | 2.46543140 |
97 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.45533361 |
98 | detection of other organism (GO:0098543) | 2.45086137 |
99 | response to thyroid hormone (GO:0097066) | 2.44637355 |
100 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.44532316 |
101 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.44043698 |
102 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 2.43954105 |
103 | positive thymic T cell selection (GO:0045059) | 2.43234667 |
104 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.42780574 |
105 | regulation of tight junction assembly (GO:2000810) | 2.42649158 |
106 | modulation by virus of host process (GO:0019054) | 2.42065955 |
107 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 2.41907112 |
108 | regulation of response to interferon-gamma (GO:0060330) | 2.41745680 |
109 | detection of molecule of bacterial origin (GO:0032490) | 2.41431410 |
110 | cell-substrate junction assembly (GO:0007044) | 2.41275771 |
111 | positive regulation of protein dephosphorylation (GO:0035307) | 2.40276626 |
112 | natural killer cell differentiation (GO:0001779) | 2.39529021 |
113 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.38941536 |
114 | detection of bacterium (GO:0016045) | 2.38888039 |
115 | regulation of interferon-gamma-mediated signaling pathway (GO:0060334) | 2.38551588 |
116 | wound healing, spreading of epidermal cells (GO:0035313) | 2.37999021 |
117 | negative regulation of Rho protein signal transduction (GO:0035024) | 2.37530104 |
118 | actin-mediated cell contraction (GO:0070252) | 2.36988613 |
119 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.36936301 |
120 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.36605667 |
121 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.36576855 |
122 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 2.35673511 |
123 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 2.34216583 |
124 | regulation of macrophage cytokine production (GO:0010935) | 2.33480709 |
125 | apoptotic process involved in morphogenesis (GO:0060561) | 2.33361057 |
126 | negative regulation of lipid storage (GO:0010888) | 2.32860129 |
127 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.31263999 |
128 | detection of external biotic stimulus (GO:0098581) | 2.30850723 |
129 | regulation of spindle organization (GO:0090224) | 2.30794103 |
130 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.30760288 |
131 | negative regulation of B cell mediated immunity (GO:0002713) | 2.29861602 |
132 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 2.29861602 |
133 | endodermal cell differentiation (GO:0035987) | 2.29822335 |
134 | pinocytosis (GO:0006907) | 2.29666153 |
135 | regulation of G0 to G1 transition (GO:0070316) | 2.29116007 |
136 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.27861920 |
137 | positive regulation of receptor recycling (GO:0001921) | 2.27105955 |
138 | hypotonic response (GO:0006971) | 2.26988618 |
139 | adenosine receptor signaling pathway (GO:0001973) | 2.26876869 |
140 | positive regulation of triglyceride lipase activity (GO:0061365) | 2.26766607 |
141 | positive regulation of lipoprotein lipase activity (GO:0051006) | 2.26766607 |
142 | Golgi transport vesicle coating (GO:0048200) | 2.26554471 |
143 | COPI coating of Golgi vesicle (GO:0048205) | 2.26554471 |
144 | response to fluid shear stress (GO:0034405) | 2.26139025 |
145 | positive regulation of interferon-alpha production (GO:0032727) | 2.25934684 |
146 | regulation of toll-like receptor 4 signaling pathway (GO:0034143) | 2.24895568 |
147 | regulation of cholesterol efflux (GO:0010874) | 2.24156091 |
148 | definitive hemopoiesis (GO:0060216) | 2.23465031 |
149 | mannose metabolic process (GO:0006013) | 2.22936120 |
150 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 2.22590701 |
151 | adherens junction assembly (GO:0034333) | 2.22242209 |
152 | thymic T cell selection (GO:0045061) | 2.21342277 |
153 | NADPH regeneration (GO:0006740) | 2.21224784 |
154 | creatine metabolic process (GO:0006600) | 2.20877420 |
155 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.20116659 |
156 | actin filament-based movement (GO:0030048) | 2.19749521 |
157 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.19346055 |
158 | regulation of necrotic cell death (GO:0010939) | 2.18636854 |
159 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 2.18423861 |
160 | positive regulation of natural killer cell differentiation (GO:0032825) | 2.18227452 |
161 | lung lobe morphogenesis (GO:0060463) | 2.18061935 |
162 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli | 2.18051611 |
163 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.17858743 |
164 | response to host (GO:0075136) | 2.17858743 |
165 | response to host defenses (GO:0052200) | 2.17858743 |
166 | negative regulation of alpha-beta T cell activation (GO:0046636) | 2.17851760 |
167 | B cell receptor signaling pathway (GO:0050853) | 2.17534007 |
168 | hyaluronan catabolic process (GO:0030214) | 2.17497667 |
169 | mRNA stabilization (GO:0048255) | 2.16959953 |
170 | RNA stabilization (GO:0043489) | 2.16959953 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.97167192 |
2 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.66922676 |
3 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.50121192 |
4 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.04064038 |
5 | MYC_22102868_ChIP-Seq_BL_Human | 3.00851643 |
6 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.69415041 |
7 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.56453356 |
8 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.48661744 |
9 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.47965139 |
10 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.32872918 |
11 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.26485874 |
12 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.21891731 |
13 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.14352600 |
14 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.14162376 |
15 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.13489762 |
16 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.12983223 |
17 | * MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.02997262 |
18 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.02825979 |
19 | * MAF_26560356_Chip-Seq_TH1_Human | 2.01715694 |
20 | * NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.01553678 |
21 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.00275496 |
22 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.98171764 |
23 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.98100518 |
24 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.94914590 |
25 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.91169514 |
26 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.86174489 |
27 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.82923463 |
28 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.81293246 |
29 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.79028604 |
30 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.76439737 |
31 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.74112172 |
32 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.71029479 |
33 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.70356787 |
34 | UTX_26944678_Chip-Seq_JUKART_Human | 1.70092928 |
35 | * RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.59256816 |
36 | * KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.58036346 |
37 | SPI1_23127762_ChIP-Seq_K562_Human | 1.56734817 |
38 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.55205280 |
39 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.54719381 |
40 | MYB_26560356_Chip-Seq_TH1_Human | 1.53080777 |
41 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.52337222 |
42 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.52139848 |
43 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.51249534 |
44 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.51169513 |
45 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.48577896 |
46 | MYB_26560356_Chip-Seq_TH2_Human | 1.47531002 |
47 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.46091598 |
48 | * CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.44153989 |
49 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.43945868 |
50 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.43723313 |
51 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.39664117 |
52 | * NCOR1_26117541_ChIP-Seq_K562_Human | 1.39524113 |
53 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.38074500 |
54 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.33086398 |
55 | * CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.32513460 |
56 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.32437166 |
57 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.31927677 |
58 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.30747558 |
59 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.29736612 |
60 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.29603321 |
61 | P68_20966046_ChIP-Seq_HELA_Human | 1.29017072 |
62 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.28480433 |
63 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.28125516 |
64 | * KDM2B_26808549_Chip-Seq_K562_Human | 1.27857740 |
65 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.25598269 |
66 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.24990336 |
67 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.24332668 |
68 | GATA1_22025678_ChIP-Seq_K562_Human | 1.24086146 |
69 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.22878297 |
70 | * MAF_26560356_Chip-Seq_TH2_Human | 1.21485655 |
71 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.20967033 |
72 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.18115698 |
73 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.17401902 |
74 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.16772678 |
75 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.16756505 |
76 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.16635225 |
77 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.15621941 |
78 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.14400849 |
79 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.13973883 |
80 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.13240526 |
81 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.12006961 |
82 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.11848802 |
83 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.11064388 |
84 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.10604186 |
85 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.10376833 |
86 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.09681002 |
87 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.09542496 |
88 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.09488607 |
89 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.09449741 |
90 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.08694743 |
91 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.08679914 |
92 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.08669314 |
93 | ATF3_27146783_Chip-Seq_COLON_Human | 1.08187557 |
94 | GATA1_19941826_ChIP-Seq_K562_Human | 1.06933381 |
95 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06685199 |
96 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.06333451 |
97 | * SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.06298543 |
98 | * SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.06298543 |
99 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.06095262 |
100 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.06007364 |
101 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.05491503 |
102 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.05200489 |
103 | * CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.05108253 |
104 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.04397816 |
105 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.04108292 |
106 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.03943601 |
107 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.03679383 |
108 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.03496157 |
109 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.02888728 |
110 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.02829657 |
111 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.02317778 |
112 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.01854719 |
113 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.01699364 |
114 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.01679526 |
115 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.01213528 |
116 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.01143766 |
117 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.00621980 |
118 | * ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.99845902 |
119 | * EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.99648244 |
120 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.99397553 |
121 | AR_21909140_ChIP-Seq_LNCAP_Human | 0.99285091 |
122 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.99179114 |
123 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.98716540 |
124 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.98288139 |
125 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.98288139 |
126 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.97013400 |
127 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.95429839 |
128 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.95237775 |
129 | BRD4_25478319_ChIP-Seq_HGPS_Human | 0.94523551 |
130 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.94471880 |
131 | GATA6_25053715_ChIP-Seq_YYC3_Human | 0.93738890 |
132 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.93001110 |
133 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.92601817 |
134 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.91895305 |
135 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.91165312 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003191_abnormal_cellular_cholesterol | 3.30859263 |
2 | MP0005451_abnormal_body_composition | 3.29038299 |
3 | MP0003705_abnormal_hypodermis_morpholog | 3.20869968 |
4 | MP0003566_abnormal_cell_adhesion | 2.56121887 |
5 | MP0000685_abnormal_immune_system | 2.33352766 |
6 | MP0010352_gastrointestinal_tract_polyps | 2.16202114 |
7 | MP0002139_abnormal_hepatobiliary_system | 2.14777677 |
8 | MP0008438_abnormal_cutaneous_collagen | 2.12593671 |
9 | MP0009278_abnormal_bone_marrow | 2.02413357 |
10 | MP0008260_abnormal_autophagy | 2.00618454 |
11 | MP0002877_abnormal_melanocyte_morpholog | 1.96165406 |
12 | MP0002396_abnormal_hematopoietic_system | 1.95761471 |
13 | MP0004233_abnormal_muscle_weight | 1.95665658 |
14 | MP0005076_abnormal_cell_differentiation | 1.92559267 |
15 | MP0003279_aneurysm | 1.89737575 |
16 | MP0010368_abnormal_lymphatic_system | 1.89471657 |
17 | MP0004808_abnormal_hematopoietic_stem | 1.87118580 |
18 | MP0004272_abnormal_basement_membrane | 1.86154435 |
19 | MP0009840_abnormal_foam_cell | 1.85395332 |
20 | MP0001849_ear_inflammation | 1.72962294 |
21 | MP0001835_abnormal_antigen_presentation | 1.72270905 |
22 | MP0001853_heart_inflammation | 1.68381716 |
23 | MP0000747_muscle_weakness | 1.67659314 |
24 | MP0004510_myositis | 1.66027758 |
25 | MP0001958_emphysema | 1.65748489 |
26 | MP0000759_abnormal_skeletal_muscle | 1.64764696 |
27 | MP0003303_peritoneal_inflammation | 1.62481096 |
28 | MP0003436_decreased_susceptibility_to | 1.60665653 |
29 | MP0001879_abnormal_lymphatic_vessel | 1.60578033 |
30 | MP0003300_gastrointestinal_ulcer | 1.58417200 |
31 | MP0004036_abnormal_muscle_relaxation | 1.58345455 |
32 | MP0005023_abnormal_wound_healing | 1.52863525 |
33 | MP0001790_abnormal_immune_system | 1.51740095 |
34 | MP0005387_immune_system_phenotype | 1.51740095 |
35 | MP0002166_altered_tumor_susceptibility | 1.48876040 |
36 | MP0003646_muscle_fatigue | 1.46605038 |
37 | MP0001800_abnormal_humoral_immune | 1.46600994 |
38 | MP0000733_abnormal_muscle_development | 1.43126770 |
39 | MP0002452_abnormal_antigen_presenting | 1.41165664 |
40 | MP0000465_gastrointestinal_hemorrhage | 1.39933931 |
41 | MP0003091_abnormal_cell_migration | 1.35359331 |
42 | MP0006054_spinal_hemorrhage | 1.34010865 |
43 | MP0005397_hematopoietic_system_phenotyp | 1.32427406 |
44 | MP0001545_abnormal_hematopoietic_system | 1.32427406 |
45 | MP0000767_abnormal_smooth_muscle | 1.30876824 |
46 | MP0005666_abnormal_adipose_tissue | 1.26516954 |
47 | MP0003453_abnormal_keratinocyte_physiol | 1.26031365 |
48 | MP0005330_cardiomyopathy | 1.25884244 |
49 | MP0002405_respiratory_system_inflammati | 1.24635144 |
50 | MP0010630_abnormal_cardiac_muscle | 1.24070974 |
51 | MP0002398_abnormal_bone_marrow | 1.22196645 |
52 | MP0005464_abnormal_platelet_physiology | 1.21372123 |
53 | MP0002106_abnormal_muscle_physiology | 1.20183677 |
54 | MP0002332_abnormal_exercise_endurance | 1.19894077 |
55 | MP0003828_pulmonary_edema | 1.19685602 |
56 | MP0002420_abnormal_adaptive_immunity | 1.18754628 |
57 | MP0001819_abnormal_immune_cell | 1.18547962 |
58 | MP0009333_abnormal_splenocyte_physiolog | 1.18036793 |
59 | MP0005058_abnormal_lysosome_morphology | 1.17878043 |
60 | MP0005375_adipose_tissue_phenotype | 1.17869309 |
61 | MP0002419_abnormal_innate_immunity | 1.16909850 |
62 | MP0005025_abnormal_response_to | 1.16714142 |
63 | MP0005167_abnormal_blood-brain_barrier | 1.16282968 |
64 | MP0006082_CNS_inflammation | 1.15703289 |
65 | MP0002723_abnormal_immune_serum | 1.13884018 |
66 | MP0002269_muscular_atrophy | 1.13673434 |
67 | MP0000569_abnormal_digit_pigmentation | 1.12076054 |
68 | MP0000689_abnormal_spleen_morphology | 1.11079565 |
69 | MP0004185_abnormal_adipocyte_glucose | 1.09877517 |
70 | MP0005275_abnormal_skin_tensile | 1.08901573 |
71 | MP0005623_abnormal_meninges_morphology | 1.08419139 |
72 | MP0001915_intracranial_hemorrhage | 1.07395069 |
73 | MP0004087_abnormal_muscle_fiber | 1.06590185 |
74 | MP0000003_abnormal_adipose_tissue | 1.05860494 |
75 | MP0000749_muscle_degeneration | 1.05668575 |
76 | MP0003724_increased_susceptibility_to | 1.04736342 |
77 | MP0000751_myopathy | 1.03778544 |
78 | MP0003656_abnormal_erythrocyte_physiolo | 1.02997780 |
79 | MP0002128_abnormal_blood_circulation | 1.02920163 |
80 | MP0002925_abnormal_cardiovascular_devel | 1.02479145 |
81 | MP0010030_abnormal_orbit_morphology | 1.02442683 |
82 | MP0000343_altered_response_to | 1.02089263 |
83 | MP0003075_altered_response_to | 1.01958160 |
84 | MP0005000_abnormal_immune_tolerance | 1.01596539 |
85 | MP0004084_abnormal_cardiac_muscle | 1.01206109 |
86 | MP0002722_abnormal_immune_system | 1.00529154 |
87 | MP0000490_abnormal_crypts_of | 1.00432649 |
88 | MP0010307_abnormal_tumor_latency | 1.00261381 |
89 | MP0003448_altered_tumor_morphology | 0.99760361 |
90 | MP0000750_abnormal_muscle_regeneration | 0.98491474 |
91 | MP0005671_abnormal_response_to | 0.98170905 |
92 | MP0000249_abnormal_blood_vessel | 0.98141227 |
93 | MP0000716_abnormal_immune_system | 0.97893683 |
94 | MP0006138_congestive_heart_failure | 0.97569701 |
95 | MP0004947_skin_inflammation | 0.97356095 |
96 | MP0002006_tumorigenesis | 0.96755640 |
97 | MP0002086_abnormal_extraembryonic_tissu | 0.96140217 |
98 | MP0010155_abnormal_intestine_physiology | 0.95768677 |
99 | MP0001533_abnormal_skeleton_physiology | 0.95277452 |
100 | MP0002429_abnormal_blood_cell | 0.92723781 |
101 | MP0001873_stomach_inflammation | 0.92607015 |
102 | MP0002088_abnormal_embryonic_growth/wei | 0.91217231 |
103 | MP0003984_embryonic_growth_retardation | 0.91102904 |
104 | MP0001614_abnormal_blood_vessel | 0.90729093 |
105 | MP0004197_abnormal_fetal_growth/weight/ | 0.90680958 |
106 | MP0005369_muscle_phenotype | 0.90391290 |
107 | MP0000703_abnormal_thymus_morphology | 0.90162731 |
108 | MP0003045_fibrosis | 0.89697857 |
109 | MP0000858_altered_metastatic_potential | 0.89156547 |
110 | MP0009785_altered_susceptibility_to | 0.88159100 |
111 | MP0000266_abnormal_heart_morphology | 0.85740160 |
112 | MP0001845_abnormal_inflammatory_respons | 0.85709752 |
113 | MP0008469_abnormal_protein_level | 0.85229793 |
114 | MP0003221_abnormal_cardiomyocyte_apopto | 0.84514391 |
115 | MP0003172_abnormal_lysosome_physiology | 0.84253053 |
116 | MP0004145_abnormal_muscle_electrophysio | 0.82917170 |
117 | MP0005670_abnormal_white_adipose | 0.82607769 |
118 | MP0003115_abnormal_respiratory_system | 0.82544411 |
119 | MP0003806_abnormal_nucleotide_metabolis | 0.81272700 |
120 | MP0003567_abnormal_fetal_cardiomyocyte | 0.81082183 |
121 | MP0004858_abnormal_nervous_system | 0.80814883 |
122 | MP0004130_abnormal_muscle_cell | 0.80651439 |
123 | MP0003763_abnormal_thymus_physiology | 0.79974989 |
124 | MP0002998_abnormal_bone_remodeling | 0.78913797 |
125 | MP0005409_darkened_coat_color | 0.78243922 |
126 | MP0002933_joint_inflammation | 0.77731706 |
127 | MP0001661_extended_life_span | 0.77184008 |
128 | MP0005380_embryogenesis_phenotype | 0.77038603 |
129 | MP0001672_abnormal_embryogenesis/_devel | 0.77038603 |
130 | MP0002148_abnormal_hypersensitivity_rea | 0.76545385 |
131 | MP0000678_abnormal_parathyroid_gland | 0.76504876 |
132 | MP0002254_reproductive_system_inflammat | 0.75266480 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nemaline bodies (HP:0003798) | 4.74212158 |
2 | Muscle fiber inclusion bodies (HP:0100299) | 4.72998715 |
3 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 4.60854278 |
4 | Exercise-induced myalgia (HP:0003738) | 4.58254609 |
5 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 3.90335632 |
6 | Cerebral aneurysm (HP:0004944) | 3.88607979 |
7 | Aortic aneurysm (HP:0004942) | 3.61798218 |
8 | Distal lower limb muscle weakness (HP:0009053) | 3.58708875 |
9 | Protrusio acetabuli (HP:0003179) | 3.57180980 |
10 | Myopathic facies (HP:0002058) | 3.55471771 |
11 | Distal lower limb amyotrophy (HP:0008944) | 3.48422232 |
12 | Increased connective tissue (HP:0009025) | 3.27088196 |
13 | Abnormality of the peritoneum (HP:0002585) | 3.11857715 |
14 | Autoimmune thrombocytopenia (HP:0001973) | 3.08373757 |
15 | Hematochezia (HP:0002573) | 2.99265287 |
16 | Aortic dissection (HP:0002647) | 2.86971264 |
17 | Abnormality of macrophages (HP:0004311) | 2.78939318 |
18 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.75352118 |
19 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.75352118 |
20 | Abnormality of glycolipid metabolism (HP:0010969) | 2.75352118 |
21 | Round ear (HP:0100830) | 2.73483092 |
22 | Ankle contracture (HP:0006466) | 2.72132676 |
23 | Spontaneous hematomas (HP:0007420) | 2.69597683 |
24 | Rhabdomyolysis (HP:0003201) | 2.67120060 |
25 | EMG: myopathic abnormalities (HP:0003458) | 2.65586401 |
26 | Type 1 muscle fiber predominance (HP:0003803) | 2.64783645 |
27 | Shallow orbits (HP:0000586) | 2.63600760 |
28 | Dysostosis multiplex (HP:0000943) | 2.58562904 |
29 | Mediastinal lymphadenopathy (HP:0100721) | 2.54700354 |
30 | Recurrent abscess formation (HP:0002722) | 2.53874189 |
31 | Polycythemia (HP:0001901) | 2.50859673 |
32 | Ulnar bowing (HP:0003031) | 2.48310117 |
33 | Abnormality of the fingertips (HP:0001211) | 2.44222955 |
34 | Increased cerebral lipofuscin (HP:0011813) | 2.42825498 |
35 | Increased density of long bones (HP:0006392) | 2.41682347 |
36 | Broad metatarsal (HP:0001783) | 2.40382787 |
37 | Achilles tendon contracture (HP:0001771) | 2.39643882 |
38 | Hyperacusis (HP:0010780) | 2.37482150 |
39 | Mitral valve prolapse (HP:0001634) | 2.37343350 |
40 | Eczematoid dermatitis (HP:0000976) | 2.36122002 |
41 | Progressive muscle weakness (HP:0003323) | 2.34698812 |
42 | Camptodactyly of toe (HP:0001836) | 2.34549724 |
43 | Long toe (HP:0010511) | 2.33876080 |
44 | Aneurysm (HP:0002617) | 2.33047585 |
45 | Muscle stiffness (HP:0003552) | 2.31913608 |
46 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.31383255 |
47 | Osteolytic defects of the hand bones (HP:0009699) | 2.31383255 |
48 | Bulbar palsy (HP:0001283) | 2.31301192 |
49 | Cellulitis (HP:0100658) | 2.29267253 |
50 | Lower limb amyotrophy (HP:0007210) | 2.27991000 |
51 | Distal arthrogryposis (HP:0005684) | 2.27976197 |
52 | Abnormality of the nasal mucosa (HP:0000433) | 2.27160532 |
53 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.23774136 |
54 | Broad face (HP:0000283) | 2.22997280 |
55 | Vacuolated lymphocytes (HP:0001922) | 2.22933008 |
56 | Axonal loss (HP:0003447) | 2.21877422 |
57 | Frequent falls (HP:0002359) | 2.20320067 |
58 | Premature rupture of membranes (HP:0001788) | 2.20078949 |
59 | Neck muscle weakness (HP:0000467) | 2.17390971 |
60 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.17231912 |
61 | Spinal cord lesions (HP:0100561) | 2.15789368 |
62 | Syringomyelia (HP:0003396) | 2.15789368 |
63 | Dilatation of the ascending aorta (HP:0005111) | 2.15363020 |
64 | Interstitial pulmonary disease (HP:0006530) | 2.12340612 |
65 | Myoglobinuria (HP:0002913) | 2.10986867 |
66 | Bicuspid aortic valve (HP:0001647) | 2.10667151 |
67 | Increased variability in muscle fiber diameter (HP:0003557) | 2.09229974 |
68 | Ragged-red muscle fibers (HP:0003200) | 2.07201439 |
69 | Cervical subluxation (HP:0003308) | 2.07103386 |
70 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.06333502 |
71 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.06333502 |
72 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.06333502 |
73 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.05444491 |
74 | Abnormality of the Achilles tendon (HP:0005109) | 2.04440566 |
75 | Disproportionate tall stature (HP:0001519) | 2.04260096 |
76 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.02359915 |
77 | Short 4th metacarpal (HP:0010044) | 2.02359915 |
78 | Spinal rigidity (HP:0003306) | 2.02000750 |
79 | Recurrent bacterial skin infections (HP:0005406) | 2.01853340 |
80 | Colitis (HP:0002583) | 2.01719962 |
81 | Nuclear cataract (HP:0100018) | 2.01514282 |
82 | Mucopolysacchariduria (HP:0008155) | 2.00442948 |
83 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.00442948 |
84 | Vertebral compression fractures (HP:0002953) | 1.99026041 |
85 | Esophageal varix (HP:0002040) | 1.98331290 |
86 | Hemiplegia (HP:0002301) | 1.97737764 |
87 | Increased serum ferritin (HP:0003281) | 1.97333207 |
88 | Generalized amyotrophy (HP:0003700) | 1.96743670 |
89 | Loss of speech (HP:0002371) | 1.94789331 |
90 | Upper motor neuron abnormality (HP:0002127) | 1.93370104 |
91 | Slender build (HP:0001533) | 1.92986712 |
92 | Exercise-induced muscle cramps (HP:0003710) | 1.91766709 |
93 | Systemic lupus erythematosus (HP:0002725) | 1.91662312 |
94 | Obstructive lung disease (HP:0006536) | 1.91457099 |
95 | Chronic obstructive pulmonary disease (HP:0006510) | 1.91457099 |
96 | Easy fatigability (HP:0003388) | 1.90572106 |
97 | Lymphangioma (HP:0100764) | 1.90528779 |
98 | Recurrent viral infections (HP:0004429) | 1.90243029 |
99 | Stridor (HP:0010307) | 1.89991634 |
100 | Ulnar deviation of the wrist (HP:0003049) | 1.89704308 |
101 | Flexion contracture of toe (HP:0005830) | 1.88545330 |
102 | Joint contractures involving the joints of the feet (HP:0100492) | 1.88545330 |
103 | Abnormal platelet volume (HP:0011876) | 1.87971851 |
104 | Elbow flexion contracture (HP:0002987) | 1.87470157 |
105 | Peritonitis (HP:0002586) | 1.85939984 |
106 | Calcaneovalgus deformity (HP:0001848) | 1.85168317 |
107 | Blue sclerae (HP:0000592) | 1.83853184 |
108 | Nephritis (HP:0000123) | 1.81718397 |
109 | Increased mean platelet volume (HP:0011877) | 1.80291375 |
110 | Urethral obstruction (HP:0000796) | 1.78096518 |
111 | Joint stiffness (HP:0001387) | 1.77427812 |
112 | J-shaped sella turcica (HP:0002680) | 1.77231189 |
113 | Bladder diverticulum (HP:0000015) | 1.77075849 |
114 | Genu recurvatum (HP:0002816) | 1.76150811 |
115 | Long eyelashes (HP:0000527) | 1.75951827 |
116 | Abnormality of the calcaneus (HP:0008364) | 1.75538028 |
117 | Recurrent fungal infections (HP:0002841) | 1.75495939 |
118 | Scapular winging (HP:0003691) | 1.74303829 |
119 | Hypertensive crisis (HP:0100735) | 1.74009015 |
120 | Bowing of the arm (HP:0006488) | 1.73618691 |
121 | Bowed forearm bones (HP:0003956) | 1.73618691 |
122 | Spondylolisthesis (HP:0003302) | 1.73510947 |
123 | Thrombocytosis (HP:0001894) | 1.73494418 |
124 | Hyporeflexia of lower limbs (HP:0002600) | 1.73324047 |
125 | Difficulty running (HP:0009046) | 1.73253813 |
126 | Persistence of primary teeth (HP:0006335) | 1.72744156 |
127 | Periodontitis (HP:0000704) | 1.72650518 |
128 | Selective tooth agenesis (HP:0001592) | 1.72280240 |
129 | Progressive external ophthalmoplegia (HP:0000590) | 1.71993633 |
130 | Glomerulonephritis (HP:0000099) | 1.71733957 |
131 | Hemorrhage of the eye (HP:0011885) | 1.70505060 |
132 | Emphysema (HP:0002097) | 1.70311582 |
133 | Knee flexion contracture (HP:0006380) | 1.70309465 |
134 | Hepatosplenomegaly (HP:0001433) | 1.69663699 |
135 | Gastrointestinal inflammation (HP:0004386) | 1.68561567 |
136 | Myocardial infarction (HP:0001658) | 1.68482313 |
137 | Muscle hypertrophy of the lower extremities (HP:0008968) | 1.68386574 |
138 | Chest pain (HP:0100749) | 1.68306854 |
139 | Fatigue (HP:0012378) | 1.67461180 |
140 | Osteomyelitis (HP:0002754) | 1.65931500 |
141 | Radial bowing (HP:0002986) | 1.65911959 |
142 | Muscle fiber splitting (HP:0003555) | 1.65735051 |
143 | Mesomelia (HP:0003027) | 1.63505512 |
144 | Gingivitis (HP:0000230) | 1.63098418 |
145 | Thoracic kyphosis (HP:0002942) | 1.62726068 |
146 | High pitched voice (HP:0001620) | 1.62391837 |
147 | Thin bony cortex (HP:0002753) | 1.62163498 |
148 | Abnormal platelet function (HP:0011869) | 1.61862960 |
149 | Impaired platelet aggregation (HP:0003540) | 1.61862960 |
150 | Dislocated radial head (HP:0003083) | 1.61801386 |
151 | Rectal prolapse (HP:0002035) | 1.61753732 |
152 | Difficulty climbing stairs (HP:0003551) | 1.61212896 |
153 | Recurrent gram-negative bacterial infections (HP:0005420) | 1.61132369 |
154 | Prolonged bleeding time (HP:0003010) | 1.60266530 |
155 | Atrophic scars (HP:0001075) | 1.59111600 |
156 | Renal duplication (HP:0000075) | 1.58854759 |
157 | Abnormality of the thoracic spine (HP:0100711) | 1.58420675 |
158 | Subaortic stenosis (HP:0001682) | 1.58026815 |
159 | Abnormality of the left ventricular outflow tract (HP:0011103) | 1.58026815 |
160 | Asymmetric septal hypertrophy (HP:0001670) | 1.57712083 |
161 | Arterial thrombosis (HP:0004420) | 1.57228093 |
162 | Broad ribs (HP:0000885) | 1.56518897 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIB3 | 3.78747263 |
2 | TTN | 3.55089352 |
3 | PKN2 | 3.21490181 |
4 | TGFBR2 | 2.77375576 |
5 | ERN1 | 2.76783147 |
6 | PRPF4B | 2.73764202 |
7 | MAP4K1 | 2.67722179 |
8 | MAP3K10 | 2.43114986 |
9 | CDK12 | 2.42790332 |
10 | SMG1 | 2.39340043 |
11 | MAP2K3 | 2.25306842 |
12 | PTK6 | 2.15999827 |
13 | RIPK4 | 2.06130750 |
14 | EEF2K | 2.03112977 |
15 | OBSCN | 1.98838939 |
16 | STK10 | 1.98588054 |
17 | RIPK1 | 1.86079022 |
18 | MUSK | 1.81196110 |
19 | PAK4 | 1.68117454 |
20 | LRRK2 | 1.63944775 |
21 | JAK3 | 1.63811721 |
22 | DMPK | 1.63489539 |
23 | TIE1 | 1.62939862 |
24 | TYK2 | 1.55356556 |
25 | ZAP70 | 1.49025707 |
26 | NEK2 | 1.45210098 |
27 | SIK1 | 1.44831500 |
28 | TAOK2 | 1.41475750 |
29 | CSF1R | 1.38489614 |
30 | IKBKB | 1.37016086 |
31 | CDC42BPA | 1.25195283 |
32 | PDGFRA | 1.24728643 |
33 | CAMK1D | 1.23186430 |
34 | TGFBR1 | 1.21782196 |
35 | KDR | 1.14931162 |
36 | PAK2 | 1.13436320 |
37 | RPS6KA4 | 1.07092040 |
38 | KSR2 | 1.06570200 |
39 | SIK2 | 1.05141980 |
40 | MAP3K1 | 1.04894182 |
41 | CSK | 1.04672517 |
42 | MYLK | 1.03431052 |
43 | TBK1 | 1.02880673 |
44 | FLT3 | 1.02063575 |
45 | NEK9 | 1.01267488 |
46 | CDK6 | 1.00902399 |
47 | MOS | 1.00481914 |
48 | KIT | 0.96116284 |
49 | BTK | 0.94731552 |
50 | MAP3K7 | 0.90427556 |
51 | PDPK1 | 0.89298185 |
52 | MAP3K6 | 0.88479480 |
53 | HCK | 0.88239371 |
54 | DDR2 | 0.87810406 |
55 | TAOK1 | 0.87688118 |
56 | JAK1 | 0.87567624 |
57 | TESK2 | 0.85243532 |
58 | PIK3CG | 0.85151020 |
59 | PTK2B | 0.84823487 |
60 | MAP3K14 | 0.84604192 |
61 | EPHB2 | 0.84435549 |
62 | MAP3K3 | 0.83908283 |
63 | STK3 | 0.83526885 |
64 | PDGFRB | 0.82719137 |
65 | ARAF | 0.82572826 |
66 | PRKG2 | 0.82482944 |
67 | MTOR | 0.82209894 |
68 | CAMK1G | 0.80869644 |
69 | MARK2 | 0.80249136 |
70 | MAP3K8 | 0.79941741 |
71 | PTK2 | 0.79773066 |
72 | EPHB1 | 0.78749669 |
73 | TRPM7 | 0.76665261 |
74 | CDK4 | 0.76432760 |
75 | PIM1 | 0.75943804 |
76 | MAPK11 | 0.74137366 |
77 | MAP3K11 | 0.73710671 |
78 | MAP2K6 | 0.73178504 |
79 | CHUK | 0.72749747 |
80 | RPS6KB2 | 0.72560114 |
81 | GRK6 | 0.72162418 |
82 | PHKG2 | 0.72158711 |
83 | PHKG1 | 0.72158711 |
84 | SIK3 | 0.71962060 |
85 | BMX | 0.70581758 |
86 | TNK2 | 0.70364285 |
87 | FES | 0.66926661 |
88 | CLK1 | 0.66324837 |
89 | MAPKAPK3 | 0.66285258 |
90 | MARK3 | 0.63674457 |
91 | EPHA2 | 0.63251808 |
92 | LCK | 0.62416436 |
93 | MAPK7 | 0.60902345 |
94 | ILK | 0.59008363 |
95 | BRD4 | 0.58476225 |
96 | CDC7 | 0.58397398 |
97 | ITK | 0.57636827 |
98 | FGR | 0.56687675 |
99 | ICK | 0.56116840 |
100 | FGFR4 | 0.56009547 |
101 | RPS6KA6 | 0.55533261 |
102 | MAPKAPK2 | 0.54667662 |
103 | RPS6KL1 | 0.54353716 |
104 | RPS6KC1 | 0.54353716 |
105 | MATK | 0.52969415 |
106 | IRAK2 | 0.52134760 |
107 | PDK1 | 0.51823465 |
108 | STK4 | 0.51795416 |
109 | NME2 | 0.50337348 |
110 | IRAK4 | 0.50101467 |
111 | IRAK3 | 0.49232832 |
112 | BRAF | 0.48903140 |
113 | JAK2 | 0.47052171 |
114 | MAP3K13 | 0.45205729 |
115 | CDK7 | 0.44887673 |
116 | TESK1 | 0.44012353 |
117 | EGFR | 0.43768846 |
118 | TEC | 0.43310675 |
119 | SYK | 0.43026504 |
120 | PRKD1 | 0.42387244 |
121 | LATS1 | 0.41793466 |
122 | BLK | 0.41428291 |
123 | MST4 | 0.40996065 |
124 | MST1R | 0.40474150 |
125 | LATS2 | 0.37948379 |
126 | AKT2 | 0.37781212 |
127 | MAP2K2 | 0.36639722 |
128 | MAPK4 | 0.35298206 |
129 | ALK | 0.34730348 |
130 | RPS6KA2 | 0.34600529 |
131 | MAPK12 | 0.33812058 |
132 | STK24 | 0.33615708 |
133 | PRKD2 | 0.33571924 |
134 | FGFR3 | 0.32941378 |
135 | INSR | 0.32734560 |
Rank | Gene Set | Z-score |
---|---|---|
1 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.31194312 |
2 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.16870633 |
3 | Leishmaniasis_Homo sapiens_hsa05140 | 2.02892410 |
4 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.87557607 |
5 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.81924205 |
6 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.81201740 |
7 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.77623459 |
8 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.71045699 |
9 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.70419808 |
10 | Focal adhesion_Homo sapiens_hsa04510 | 1.70142252 |
11 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.63710850 |
12 | Adherens junction_Homo sapiens_hsa04520 | 1.63135190 |
13 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.62671765 |
14 | Viral myocarditis_Homo sapiens_hsa05416 | 1.61094276 |
15 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.58272917 |
16 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.57446885 |
17 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.57074967 |
18 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.55981860 |
19 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.46186315 |
20 | Apoptosis_Homo sapiens_hsa04210 | 1.44846371 |
21 | Platelet activation_Homo sapiens_hsa04611 | 1.43949778 |
22 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.41664538 |
23 | Measles_Homo sapiens_hsa05162 | 1.39780836 |
24 | Base excision repair_Homo sapiens_hsa03410 | 1.37635148 |
25 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.35112734 |
26 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.35110131 |
27 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.34154182 |
28 | Influenza A_Homo sapiens_hsa05164 | 1.29622455 |
29 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.27474350 |
30 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.27175839 |
31 | Insulin resistance_Homo sapiens_hsa04931 | 1.26631654 |
32 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.23942427 |
33 | Amoebiasis_Homo sapiens_hsa05146 | 1.22988815 |
34 | Galactose metabolism_Homo sapiens_hsa00052 | 1.21862833 |
35 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.20738755 |
36 | Malaria_Homo sapiens_hsa05144 | 1.19908601 |
37 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.17144356 |
38 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.16530421 |
39 | HTLV-I infection_Homo sapiens_hsa05166 | 1.16099800 |
40 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.15458538 |
41 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.15372138 |
42 | Lysine degradation_Homo sapiens_hsa00310 | 1.14451592 |
43 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.14363027 |
44 | Shigellosis_Homo sapiens_hsa05131 | 1.13891284 |
45 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.11422981 |
46 | Tuberculosis_Homo sapiens_hsa05152 | 1.11363136 |
47 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.10705603 |
48 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.10666690 |
49 | Legionellosis_Homo sapiens_hsa05134 | 1.10272212 |
50 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 1.10067020 |
51 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.09361824 |
52 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.06687113 |
53 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.06684603 |
54 | Pertussis_Homo sapiens_hsa05133 | 1.04748620 |
55 | Hepatitis B_Homo sapiens_hsa05161 | 1.00603738 |
56 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.00271389 |
57 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.00112956 |
58 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.98481414 |
59 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.98287180 |
60 | Other glycan degradation_Homo sapiens_hsa00511 | 0.96856032 |
61 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.95602605 |
62 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.95302155 |
63 | DNA replication_Homo sapiens_hsa03030 | 0.95255784 |
64 | Thyroid cancer_Homo sapiens_hsa05216 | 0.95053604 |
65 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.94715682 |
66 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.93047204 |
67 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.92545776 |
68 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.91828584 |
69 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.90096163 |
70 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.90064315 |
71 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.89512478 |
72 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.88577167 |
73 | Allograft rejection_Homo sapiens_hsa05330 | 0.88540868 |
74 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.87062484 |
75 | Salmonella infection_Homo sapiens_hsa05132 | 0.85697397 |
76 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.85498441 |
77 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.85154860 |
78 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.84377676 |
79 | Phagosome_Homo sapiens_hsa04145 | 0.83917206 |
80 | Pathways in cancer_Homo sapiens_hsa05200 | 0.82663395 |
81 | Prion diseases_Homo sapiens_hsa05020 | 0.81987338 |
82 | Bladder cancer_Homo sapiens_hsa05219 | 0.80990647 |
83 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.80199471 |
84 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.79465847 |
85 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.78942691 |
86 | Hepatitis C_Homo sapiens_hsa05160 | 0.77867796 |
87 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.77837636 |
88 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.76600646 |
89 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.75369021 |
90 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.75017288 |
91 | Prostate cancer_Homo sapiens_hsa05215 | 0.74434570 |
92 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.74157635 |
93 | Endometrial cancer_Homo sapiens_hsa05213 | 0.72418847 |
94 | Glioma_Homo sapiens_hsa05214 | 0.71637223 |
95 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.70008468 |
96 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.69818251 |
97 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.69295409 |
98 | Colorectal cancer_Homo sapiens_hsa05210 | 0.69197364 |
99 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.69057427 |
100 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.68917673 |
101 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.68771602 |
102 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.67563670 |
103 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.67314641 |
104 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.67069482 |
105 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.65633951 |
106 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.63819490 |
107 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.63127429 |
108 | Endocytosis_Homo sapiens_hsa04144 | 0.62556027 |
109 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.61625354 |
110 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.60819825 |
111 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.59970411 |
112 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.59562822 |
113 | Carbon metabolism_Homo sapiens_hsa01200 | 0.58538119 |
114 | Cell cycle_Homo sapiens_hsa04110 | 0.58378417 |
115 | Lysosome_Homo sapiens_hsa04142 | 0.57482935 |
116 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.56796359 |
117 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.55602910 |
118 | Spliceosome_Homo sapiens_hsa03040 | 0.55151528 |
119 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.54129142 |
120 | RNA transport_Homo sapiens_hsa03013 | 0.53857530 |
121 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.53538243 |
122 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.53182951 |
123 | Asthma_Homo sapiens_hsa05310 | 0.53012654 |
124 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.52040349 |
125 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.52006927 |
126 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.51346951 |
127 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.50920564 |
128 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.50277807 |