FILIP1L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1actin-mediated cell contraction (GO:0070252)4.73064841
2antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.34322724
3response to muscle activity (GO:0014850)3.96545068
4regulation of skeletal muscle contraction (GO:0014819)3.95611399
5myofibril assembly (GO:0030239)3.93146467
6sarcoplasmic reticulum calcium ion transport (GO:0070296)3.76747662
7cardiac myofibril assembly (GO:0055003)3.75958825
8actin filament-based movement (GO:0030048)3.73092787
9regulation of interleukin-12 biosynthetic process (GO:0045075)3.71320246
10cell adhesion mediated by integrin (GO:0033627)3.61977643
11antigen processing and presentation of endogenous antigen (GO:0019883)3.59221689
12sarcomere organization (GO:0045214)3.53789027
13regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.53325026
14response to stimulus involved in regulation of muscle adaptation (GO:0014874)3.49977937
15metanephric mesenchyme development (GO:0072075)3.45763275
16tooth mineralization (GO:0034505)3.39448190
17chondrocyte proliferation (GO:0035988)3.29213959
18cell proliferation involved in metanephros development (GO:0072203)3.25809186
19skeletal muscle contraction (GO:0003009)3.24646162
20kidney mesenchyme development (GO:0072074)3.23187139
21wound healing, spreading of epidermal cells (GO:0035313)3.20556829
22regulation of dendritic cell antigen processing and presentation (GO:0002604)3.18667649
23positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.17049396
24actomyosin structure organization (GO:0031032)3.15000712
25regulation of relaxation of muscle (GO:1901077)3.12101008
26regulation of interferon-beta biosynthetic process (GO:0045357)3.11089813
27cellular response to zinc ion (GO:0071294)3.08182476
28vascular endothelial growth factor signaling pathway (GO:0038084)3.06142747
29endocardial cushion development (GO:0003197)3.05830866
30endodermal cell differentiation (GO:0035987)3.05283096
31collagen fibril organization (GO:0030199)3.04363226
32positive regulation of interferon-alpha production (GO:0032727)3.03183372
33positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr3.02999659
34positive regulation of gamma-delta T cell activation (GO:0046645)3.00964979
35regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.98153358
36regulation of interferon-alpha production (GO:0032647)2.94649109
37muscle contraction (GO:0006936)2.91429141
38antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.90526720
39antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.90526720
40substrate-dependent cell migration (GO:0006929)2.90470704
41NIK/NF-kappaB signaling (GO:0038061)2.88871495
42cellular response to interferon-alpha (GO:0035457)2.86605754
43positive regulation by symbiont of host defense response (GO:0052509)2.86471931
44modulation by symbiont of host defense response (GO:0052031)2.86471931
45modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.86471931
46modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.86471931
47positive regulation by organism of defense response of other organism involved in symbiotic interact2.86471931
48modulation by symbiont of host immune response (GO:0052553)2.86471931
49glomerular basement membrane development (GO:0032836)2.85998613
50positive regulation of natural killer cell differentiation (GO:0032825)2.85566672
51smooth muscle tissue development (GO:0048745)2.83722516
52negative regulation of fibrinolysis (GO:0051918)2.83586425
53B cell receptor signaling pathway (GO:0050853)2.82280001
54cell proliferation involved in kidney development (GO:0072111)2.79595408
55regulation of apoptotic cell clearance (GO:2000425)2.78007915
56negative regulation of protein localization to cell surface (GO:2000009)2.76553071
57regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.76362828
58plasma membrane repair (GO:0001778)2.75118690
59regulation of macrophage cytokine production (GO:0010935)2.74713055
60regulation of T cell tolerance induction (GO:0002664)2.74247576
61basement membrane organization (GO:0071711)2.73058194
62positive regulation of endothelial cell apoptotic process (GO:2000353)2.72006302
63neutrophil activation involved in immune response (GO:0002283)2.69512901
64myoblast fusion (GO:0007520)2.65964802
65hemidesmosome assembly (GO:0031581)2.64745585
66negative regulation of protein activation cascade (GO:2000258)2.64546216
67membrane raft organization (GO:0031579)2.63999301
68striated muscle contraction (GO:0006941)2.63455343
69growth hormone receptor signaling pathway (GO:0060396)2.62604031
70cell migration involved in heart development (GO:0060973)2.62059012
71positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.59405447
72muscle system process (GO:0003012)2.59084063
73wound healing, spreading of cells (GO:0044319)2.57422748
74insulin-like growth factor receptor signaling pathway (GO:0048009)2.56980226
75response to muramyl dipeptide (GO:0032495)2.56919179
76skin morphogenesis (GO:0043589)2.56150988
77regulation of B cell receptor signaling pathway (GO:0050855)2.55830373
78negative regulation of B cell proliferation (GO:0030889)2.55458904
79regulation of complement activation (GO:0030449)2.55118004
80I-kappaB phosphorylation (GO:0007252)2.55043930
81lymph vessel development (GO:0001945)2.54811729
82negative regulation of complement activation (GO:0045916)2.54393977
83apoptotic cell clearance (GO:0043277)2.54391111
84skeletal muscle tissue development (GO:0007519)2.53237327
85positive thymic T cell selection (GO:0045059)2.53130064
86peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.52955575
87regulation of plasminogen activation (GO:0010755)2.52528486
88extracellular matrix assembly (GO:0085029)2.50417323
89response to inactivity (GO:0014854)2.50056348
90regulation of protein activation cascade (GO:2000257)2.49304248
91positive regulation of osteoblast proliferation (GO:0033690)2.48627195
92positive regulation of macrophage cytokine production (GO:0060907)2.48372776
93positive regulation of extracellular matrix organization (GO:1903055)2.47220929
94protein heterotrimerization (GO:0070208)2.47008595
95hypotonic response (GO:0006971)2.46450248
96sequestering of extracellular ligand from receptor (GO:0035581)2.46098745
97regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.45396527
98extracellular fibril organization (GO:0043206)2.44141464
99negative regulation of fatty acid transport (GO:2000192)2.43929912
100neutrophil activation (GO:0042119)2.43542006
101collagen metabolic process (GO:0032963)2.43339717
102peptidyl-glutamic acid carboxylation (GO:0017187)2.43028873
103protein carboxylation (GO:0018214)2.43028873
104macrophage activation involved in immune response (GO:0002281)2.42707328
105skeletal muscle adaptation (GO:0043501)2.41820341
106interferon-gamma-mediated signaling pathway (GO:0060333)2.41296823
107negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.39463500
108positive regulation of blood vessel endothelial cell migration (GO:0043536)2.39297204
109actin filament depolymerization (GO:0030042)2.39169911
110renal tubule morphogenesis (GO:0061333)2.38933223
111myotube cell development (GO:0014904)2.38355193
112cell-substrate junction assembly (GO:0007044)2.38048760
113lymphangiogenesis (GO:0001946)2.37232077
114skeletal muscle fiber development (GO:0048741)2.37118208
115response to laminar fluid shear stress (GO:0034616)2.36862422
116syncytium formation by plasma membrane fusion (GO:0000768)2.35400399
117regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.35324026
118regulation of B cell differentiation (GO:0045577)2.34652513
119response to fluid shear stress (GO:0034405)2.33159537
120collagen catabolic process (GO:0030574)2.32680501
121regulation of necroptotic process (GO:0060544)2.32107830
122muscle tissue morphogenesis (GO:0060415)2.32097737
123nephron tubule morphogenesis (GO:0072078)2.31765057
124nephron epithelium morphogenesis (GO:0072088)2.31765057
125multicellular organismal macromolecule metabolic process (GO:0044259)2.31727960
126tonic smooth muscle contraction (GO:0014820)2.31646055
127granulocyte activation (GO:0036230)2.31378575
128extracellular matrix disassembly (GO:0022617)2.31044851
129keratan sulfate catabolic process (GO:0042340)2.30697030
130germinal center formation (GO:0002467)2.30514558
131immunoglobulin mediated immune response (GO:0016064)2.28344711
132regulation of fibrinolysis (GO:0051917)2.28309354
133regulation of B cell proliferation (GO:0030888)2.28102945
134JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.27962216
135cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.26763093
136establishment of endothelial barrier (GO:0061028)2.26549352
137multicellular organismal metabolic process (GO:0044236)2.26251842
138cellular response to growth hormone stimulus (GO:0071378)2.24428182
139lung vasculature development (GO:0060426)2.23819885
140cardiac muscle hypertrophy (GO:0003300)2.23021178
141positive regulation of interleukin-12 production (GO:0032735)2.22996845
142positive regulation of collagen biosynthetic process (GO:0032967)2.22691251
143retina vasculature morphogenesis in camera-type eye (GO:0061299)2.22643579
144B cell proliferation (GO:0042100)2.22400119
145multicellular organismal catabolic process (GO:0044243)2.22286257
146venous blood vessel morphogenesis (GO:0048845)2.22276131
147desmosome organization (GO:0002934)2.22096754
148actin-myosin filament sliding (GO:0033275)2.21964282
149muscle filament sliding (GO:0030049)2.21964282
150regulation of gamma-delta T cell differentiation (GO:0045586)2.21394880
151pathway-restricted SMAD protein phosphorylation (GO:0060389)2.20630112
152regulation of muscle hypertrophy (GO:0014743)2.20439511
153heterotypic cell-cell adhesion (GO:0034113)2.20095795
154regulation of interleukin-12 production (GO:0032655)2.19342074
155glomerular filtration (GO:0003094)2.18909104
156substrate adhesion-dependent cell spreading (GO:0034446)2.18906040
157myeloid dendritic cell differentiation (GO:0043011)2.18787032
158negative regulation of leukocyte chemotaxis (GO:0002689)2.18716164
159regulation of cardiac muscle hypertrophy (GO:0010611)2.18439560
160neuron projection extension involved in neuron projection guidance (GO:1902284)2.17893703
161axon extension involved in axon guidance (GO:0048846)2.17893703
162positive regulation of muscle hypertrophy (GO:0014742)2.17870764
163positive regulation of cardiac muscle hypertrophy (GO:0010613)2.17870764
164tyrosine phosphorylation of STAT protein (GO:0007260)2.17615468
165mesodermal cell differentiation (GO:0048333)2.16513761
166positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.16345237
167muscle structure development (GO:0061061)2.16142939
168positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.16142073
169regulation of gamma-delta T cell activation (GO:0046643)2.15700155
170platelet-derived growth factor receptor signaling pathway (GO:0048008)2.15355513
171positive regulation of macrophage differentiation (GO:0045651)2.14901434
172cytoplasmic mRNA processing body assembly (GO:0033962)2.14178751
173renal filtration (GO:0097205)2.14170288
174integrin-mediated signaling pathway (GO:0007229)2.13914026
175positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.12416053
176cellular response to vitamin D (GO:0071305)2.12286160
177negative regulation of interleukin-12 production (GO:0032695)2.12078249
178regulation of integrin activation (GO:0033623)2.12024705

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.27401804
2TP63_17297297_ChIP-ChIP_HaCaT_Human4.98741619
3IRF8_22096565_ChIP-ChIP_GC-B_Human4.49377275
4NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.68752704
5TRIM28_21343339_ChIP-Seq_HEK293_Human3.66419525
6STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.41888918
7EGR1_19374776_ChIP-ChIP_THP-1_Human3.31673198
8IRF8_21731497_ChIP-ChIP_J774_Mouse3.15430032
9BP1_19119308_ChIP-ChIP_Hs578T_Human2.84014487
10RARG_19884340_ChIP-ChIP_MEFs_Mouse2.75338574
11RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.64220831
12TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.63273335
13IRF8_27001747_Chip-Seq_BMDM_Mouse2.59341874
14IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.53758703
15STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.42851324
16SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.34028867
17IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.31196418
18SMAD_19615063_ChIP-ChIP_OVARY_Human2.30222827
19NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.23943732
20TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.11741541
21* CJUN_26792858_Chip-Seq_BT549_Human1.97182896
22RUNX_20019798_ChIP-Seq_JUKART_Human1.96522791
23* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.93482882
24ZNF217_24962896_ChIP-Seq_MCF-7_Human1.92655374
25SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.90983796
26CLOCK_20551151_ChIP-Seq_293T_Human1.90406949
27MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.89330146
28* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.89155495
29MYB_21317192_ChIP-Seq_ERMYB_Mouse1.87900833
30ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.87078483
31RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.86847098
32* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.85646620
33SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.83610119
34SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.83610119
35NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.80181177
36GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.73024644
37GATA2_21666600_ChIP-Seq_HMVEC_Human1.70591164
38ELK3_25401928_ChIP-Seq_HUVEC_Human1.67649251
39BRD4_25478319_ChIP-Seq_HGPS_Human1.67544602
40* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.63559757
41STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.60411887
42* NFIB_24661679_ChIP-Seq_LUNG_Mouse1.59334385
43ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.59116474
44* FOXA2_19822575_ChIP-Seq_HepG2_Human1.58277068
45BRD4_27068464_Chip-Seq_AML-cells_Mouse1.57507247
46SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.55169722
47PPAR_26484153_Chip-Seq_NCI-H1993_Human1.54290127
48MAF_26560356_Chip-Seq_TH1_Human1.54031077
49MYB_26560356_Chip-Seq_TH2_Human1.52039706
50FOXO3_23340844_ChIP-Seq_DLD1_Human1.49582908
51VDR_24787735_ChIP-Seq_THP-1_Human1.48615717
52* LXR_22158963_ChIP-Seq_LIVER_Mouse1.45931391
53AR_21572438_ChIP-Seq_LNCaP_Human1.45397538
54STAT4_19710469_ChIP-ChIP_TH1__Mouse1.43632362
55EP300_21415370_ChIP-Seq_HL-1_Mouse1.43523439
56VDR_24763502_ChIP-Seq_THP-1_Human1.42509833
57SALL4_18804426_ChIP-ChIP_XEN_Mouse1.41126143
58PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.40764987
59MYC_22102868_ChIP-Seq_BL_Human1.40732662
60KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.39733450
61TCF4_18268006_ChIP-ChIP_LS174T_Human1.39116342
62ESR1_21235772_ChIP-Seq_MCF-7_Human1.38352431
63PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.37495770
64MYB_26560356_Chip-Seq_TH1_Human1.36262155
65CDX2_19796622_ChIP-Seq_MESCs_Mouse1.36130090
66CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.34157600
67TCF7_22412390_ChIP-Seq_EML_Mouse1.33657289
68SOX9_24532713_ChIP-Seq_HFSC_Mouse1.33082916
69* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.31941175
70GBX2_23144817_ChIP-Seq_PC3_Human1.31611702
71* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.31276880
72CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.30873445
73VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.30770104
74NRF2_20460467_ChIP-Seq_MEFs_Mouse1.28582582
75NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.28582582
76* TBX20_22328084_ChIP-Seq_HEART_Mouse1.28196263
77* TBX20_22080862_ChIP-Seq_HEART_Mouse1.28196263
78PIAS1_25552417_ChIP-Seq_VCAP_Human1.27715352
79SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.27467010
80VDR_21846776_ChIP-Seq_THP-1_Human1.27284842
81SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.26282721
82* ARNT_22903824_ChIP-Seq_MCF-7_Human1.26270438
83STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.26012702
84CTNNB1_20460455_ChIP-Seq_HCT116_Human1.24704976
85* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.23606308
86UTX_26944678_Chip-Seq_JUKART_Human1.23314208
87TP53_16413492_ChIP-PET_HCT116_Human1.22584069
88ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.22547667
89BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.22139392
90AHR_22903824_ChIP-Seq_MCF-7_Human1.22138849
91RXR_22158963_ChIP-Seq_LIVER_Mouse1.21797243
92WT1_19549856_ChIP-ChIP_CCG9911_Human1.21452150
93HIF1A_21447827_ChIP-Seq_MCF-7_Human1.21156600
94SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.20101065
95KDM2B_26808549_Chip-Seq_DND41_Human1.20018265
96MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.19666768
97PU_27001747_Chip-Seq_BMDM_Mouse1.19183097
98SOX2_20726797_ChIP-Seq_SW620_Human1.19086104
99FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.19057220
100EZH2_18974828_ChIP-Seq_MESCs_Mouse1.18638125
101RNF2_18974828_ChIP-Seq_MESCs_Mouse1.18638125
102* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.18354618
103ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.14610934
104UBF1/2_26484160_Chip-Seq_HMECs_Human1.14604365
105EED_16625203_ChIP-ChIP_MESCs_Mouse1.13229237
106EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.11856036
107KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.11685815
108* SPI1_23127762_ChIP-Seq_K562_Human1.11668386
109NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.10577174
110PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.10065938
111SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.08941461
112PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.08307154
113MTF2_20144788_ChIP-Seq_MESCs_Mouse1.05975167
114ESR2_21235772_ChIP-Seq_MCF-7_Human1.05708829
115NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.05273144
116KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.04895524
117THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.04726037
118SPI1_23547873_ChIP-Seq_NB4_Human1.04183141
119* SMAD3_21741376_ChIP-Seq_HESCs_Human1.04069826
120WT1_25993318_ChIP-Seq_PODOCYTE_Human1.03725138
121RUNX1_22412390_ChIP-Seq_EML_Mouse1.03520699
122SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.03507837
123ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.02965688
124NR3C1_23031785_ChIP-Seq_PC12_Mouse1.02865256
125RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.02364826
126KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.01788179
127RXR_22108803_ChIP-Seq_LS180_Human1.01594757
128ISL1_27105846_Chip-Seq_CPCs_Mouse1.01575149
129SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.01418065
130NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.01217202
131P63_26484246_Chip-Seq_KERATINOCYTES_Human1.01150856
132E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.00906676
133* PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.00898751
134FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.00440699
135ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.99500052
136ESR1_20079471_ChIP-ChIP_T-47D_Human0.98512439
137SMAD4_21799915_ChIP-Seq_A2780_Human0.97801357
138P300_27058665_Chip-Seq_ZR-75-30cells_Human0.97783099
139TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.97278728
140PCGF2_27294783_Chip-Seq_NPCs_Mouse0.95724815
141PCGF2_27294783_Chip-Seq_ESCs_Mouse0.94101604
142* TP63_23658742_ChIP-Seq_EP156T_Human0.93990013
143WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.93899603
144TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.93836223
145TP53_18474530_ChIP-ChIP_U2OS_Human0.92942831
146JARID2_20075857_ChIP-Seq_MESCs_Mouse0.92848192
147SMC1_22415368_ChIP-Seq_MEFs_Mouse0.92630252
148PPARA_22158963_ChIP-Seq_LIVER_Mouse0.92220458
149* FOXM1_26456572_ChIP-Seq_MCF-7_Human0.91458464
150* SMAD4_21741376_ChIP-Seq_HESCs_Human0.91200306
151ZFP57_27257070_Chip-Seq_ESCs_Mouse0.89171636
152RBPJ_22232070_ChIP-Seq_NCS_Mouse0.88809489
153* SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.88204794
154SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.88097703
155SUZ12_27294783_Chip-Seq_NPCs_Mouse0.87479753
156PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.85933791
157SMAD3_21741376_ChIP-Seq_EPCs_Human0.85782607
158DROSHA_22980978_ChIP-Seq_HELA_Human0.84959573
159EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.84533367

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen4.31669201
2MP0005275_abnormal_skin_tensile3.05540513
3MP0004145_abnormal_muscle_electrophysio3.00026857
4MP0003705_abnormal_hypodermis_morpholog2.88133965
5MP0003646_muscle_fatigue2.77566519
6MP0001835_abnormal_antigen_presentation2.67197350
7MP0004036_abnormal_muscle_relaxation2.62554615
8MP0003950_abnormal_plasma_membrane2.62274545
9MP0005503_abnormal_tendon_morphology2.62228996
10MP0003566_abnormal_cell_adhesion2.42775696
11MP0003279_aneurysm2.34596477
12MP0010352_gastrointestinal_tract_polyps2.29333270
13MP0005387_immune_system_phenotype2.10287045
14MP0001790_abnormal_immune_system2.10287045
15MP0003303_peritoneal_inflammation2.09036323
16MP0003300_gastrointestinal_ulcer2.08514796
17MP0004510_myositis2.02932940
18MP0000013_abnormal_adipose_tissue2.01236190
19MP0002106_abnormal_muscle_physiology1.97709756
20MP0005369_muscle_phenotype1.92033779
21MP0005620_abnormal_muscle_contractility1.91178441
22MP0000685_abnormal_immune_system1.87903237
23MP0004272_abnormal_basement_membrane1.87609742
24MP0001958_emphysema1.87070228
25MP0003045_fibrosis1.85640193
26MP0003091_abnormal_cell_migration1.82822460
27MP0001800_abnormal_humoral_immune1.80942648
28MP0002166_altered_tumor_susceptibility1.76653104
29MP0000747_muscle_weakness1.76393426
30MP0004130_abnormal_muscle_cell1.75115233
31MP0010368_abnormal_lymphatic_system1.73669751
32MP0005000_abnormal_immune_tolerance1.69895708
33MP0002452_abnormal_antigen_presenting1.69727092
34MP0009780_abnormal_chondrocyte_physiolo1.68970794
35MP0003436_decreased_susceptibility_to1.68538772
36MP0000733_abnormal_muscle_development1.64057171
37MP0001879_abnormal_lymphatic_vessel1.63366027
38MP0005023_abnormal_wound_healing1.61838719
39MP0002269_muscular_atrophy1.60593455
40MP0002148_abnormal_hypersensitivity_rea1.56891106
41MP0001853_heart_inflammation1.56165431
42MP0002006_tumorigenesis1.55678014
43MP0006054_spinal_hemorrhage1.55596973
44MP0002060_abnormal_skin_morphology1.54271910
45MP0003828_pulmonary_edema1.53012924
46MP0010234_abnormal_vibrissa_follicle1.51778670
47MP0000767_abnormal_smooth_muscle1.51743892
48MP0006138_congestive_heart_failure1.50805247
49MP0005076_abnormal_cell_differentiation1.50173060
50MP0002896_abnormal_bone_mineralization1.48140066
51MP0005670_abnormal_white_adipose1.46605419
52MP0009785_altered_susceptibility_to1.46225348
53MP0002419_abnormal_innate_immunity1.38071036
54MP0004233_abnormal_muscle_weight1.37896023
55MP0002723_abnormal_immune_serum1.36694099
56MP0009384_cardiac_valve_regurgitation1.36566226
57MP0004947_skin_inflammation1.35873254
58MP0001299_abnormal_eye_distance/1.35556014
59MP0005451_abnormal_body_composition1.34492817
60MP0002933_joint_inflammation1.31954520
61MP0002127_abnormal_cardiovascular_syste1.30862663
62MP0002420_abnormal_adaptive_immunity1.28758209
63MP0001819_abnormal_immune_cell1.28399657
64MP0005623_abnormal_meninges_morphology1.28160195
65MP0001533_abnormal_skeleton_physiology1.27748881
66MP0000534_abnormal_ureter_morphology1.27639607
67MP0001243_abnormal_dermal_layer1.26405095
68MP0005671_abnormal_response_to1.25707985
69MP0000750_abnormal_muscle_regeneration1.24276495
70MP0000569_abnormal_digit_pigmentation1.22584163
71MP0000003_abnormal_adipose_tissue1.22356508
72MP0001542_abnormal_bone_strength1.22117860
73MP0005025_abnormal_response_to1.21644067
74MP0003448_altered_tumor_morphology1.20736510
75MP0005257_abnormal_intraocular_pressure1.20722769
76MP0003941_abnormal_skin_development1.19082107
77MP0003453_abnormal_keratinocyte_physiol1.16385168
78MP0010155_abnormal_intestine_physiology1.15546792
79MP0002405_respiratory_system_inflammati1.13657973
80MP0004484_altered_response_of1.13180216
81MP0003724_increased_susceptibility_to1.12670445
82MP0009250_abnormal_appendicular_skeleto1.12397050
83MP0002168_other_aberrant_phenotype1.11911311
84MP0002998_abnormal_bone_remodeling1.10466079
85MP0004215_abnormal_myocardial_fiber1.10326114
86MP0000343_altered_response_to1.09745854
87MP0004808_abnormal_hematopoietic_stem1.09232147
88MP0010630_abnormal_cardiac_muscle1.08944822
89MP0002332_abnormal_exercise_endurance1.07618193
90MP0005390_skeleton_phenotype1.07166863
91MP0004087_abnormal_muscle_fiber1.06423269
92MP0005595_abnormal_vascular_smooth1.05098698
93MP0005508_abnormal_skeleton_morphology1.04162780
94MP0005164_abnormal_response_to1.03593840
95MP0001661_extended_life_span1.03573665
96MP0002877_abnormal_melanocyte_morpholog1.03308631
97MP0003868_abnormal_feces_composition1.01349817
98MP0004084_abnormal_cardiac_muscle1.01347471
99MP0002254_reproductive_system_inflammat1.01018570
100MP0005084_abnormal_gallbladder_morpholo1.00157654
101MP0003252_abnormal_bile_duct0.98959872
102MP0010386_abnormal_urinary_bladder0.98521266
103MP0000716_abnormal_immune_system0.96649656
104MP0002138_abnormal_hepatobiliary_system0.96563906
105MP0003385_abnormal_body_wall0.96239042
106MP0002398_abnormal_bone_marrow0.95331127
107MP0000749_muscle_degeneration0.93950317
108MP0001845_abnormal_inflammatory_respons0.93192877
109MP0002295_abnormal_pulmonary_circulatio0.90235886
110MP0002128_abnormal_blood_circulation0.88922558
111MP0009278_abnormal_bone_marrow0.88864236
112MP0003763_abnormal_thymus_physiology0.88479360
113MP0003942_abnormal_urinary_system0.88342727
114MP0005360_urolithiasis0.85433901
115MP0000858_altered_metastatic_potential0.84952656
116MP0005330_cardiomyopathy0.84696858
117MP0002971_abnormal_brown_adipose0.84328794
118MP0005409_darkened_coat_color0.84301292
119MP0001873_stomach_inflammation0.83887176
120MP0000751_myopathy0.83696016
121MP0002108_abnormal_muscle_morphology0.83294691
122MP0004134_abnormal_chest_morphology0.83254681
123MP0001270_distended_abdomen0.82934931
124MP0009764_decreased_sensitivity_to0.82211310
125MP0001348_abnormal_lacrimal_gland0.82178902
126MP0002396_abnormal_hematopoietic_system0.81867767
127MP0008775_abnormal_heart_ventricle0.81775343
128MP0000163_abnormal_cartilage_morphology0.80806372
129MP0002925_abnormal_cardiovascular_devel0.79699879
130MP0005375_adipose_tissue_phenotype0.79126760
131MP0003795_abnormal_bone_structure0.77845092
132MP0001614_abnormal_blood_vessel0.77621146
133MP0000689_abnormal_spleen_morphology0.77201384
134MP0000762_abnormal_tongue_morphology0.77135517
135MP0009840_abnormal_foam_cell0.77076050
136MP0000249_abnormal_blood_vessel0.75914405
137MP0005165_increased_susceptibility_to0.75242369
138MP0002115_abnormal_skeleton_extremities0.75152673
139MP0001666_abnormal_nutrient_absorption0.74775733
140MP0002429_abnormal_blood_cell0.74575529
141MP0001915_intracranial_hemorrhage0.74120507
142MP0005365_abnormal_bile_salt0.74057475
143MP0002009_preneoplasia0.73415474
144MP0005464_abnormal_platelet_physiology0.72872239
145MP0004185_abnormal_adipocyte_glucose0.72227068
146MP0002722_abnormal_immune_system0.72215346
147MP0005385_cardiovascular_system_phenoty0.71483701
148MP0001544_abnormal_cardiovascular_syste0.71483701
149MP0002972_abnormal_cardiac_muscle0.71473343
150MP0000759_abnormal_skeletal_muscle0.70957406
151MP0010329_abnormal_lipoprotein_level0.67290182
152MP0000266_abnormal_heart_morphology0.65926841
153MP0003283_abnormal_digestive_organ0.65892444
154MP0000462_abnormal_digestive_system0.63319481
155MP0005167_abnormal_blood-brain_barrier0.61831093

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)4.58829828
2Premature rupture of membranes (HP:0001788)4.55964932
3Exercise-induced myalgia (HP:0003738)4.52964886
4Aortic dissection (HP:0002647)4.04503483
5Aortic aneurysm (HP:0004942)3.92868483
6Ulnar deviation of the wrist (HP:0003049)3.73264198
7Cerebral aneurysm (HP:0004944)3.54277793
8Peritonitis (HP:0002586)3.32617700
9Exercise-induced muscle cramps (HP:0003710)3.31790675
10Atrophic scars (HP:0001075)3.24341294
11Muscle hypertrophy of the lower extremities (HP:0008968)3.22071551
12Increased connective tissue (HP:0009025)3.18739062
13Asymmetric septal hypertrophy (HP:0001670)3.16614966
14Type 1 muscle fiber predominance (HP:0003803)3.15124282
15Increased variability in muscle fiber diameter (HP:0003557)3.10822664
16Abnormality of skeletal muscle fiber size (HP:0012084)3.09232814
17Dilatation of the ascending aorta (HP:0005111)3.07154024
18Osteolytic defects of the hand bones (HP:0009699)3.03314475
19Osteolytic defects of the phalanges of the hand (HP:0009771)3.03314475
20Hematochezia (HP:0002573)3.02152354
21Calf muscle hypertrophy (HP:0008981)2.96553911
22Myopathic facies (HP:0002058)2.90767729
23Shallow orbits (HP:0000586)2.90278814
24Neck muscle weakness (HP:0000467)2.87160626
25Slender build (HP:0001533)2.79777786
26Overgrowth (HP:0001548)2.75954439
27Agammaglobulinemia (HP:0004432)2.75536865
28Deep venous thrombosis (HP:0002625)2.75394952
29Broad metatarsal (HP:0001783)2.75180884
30Neonatal short-limb short stature (HP:0008921)2.69731800
31Increased density of long bones (HP:0006392)2.67269146
32EMG: myopathic abnormalities (HP:0003458)2.66114106
33Cellulitis (HP:0100658)2.65853409
34Eczematoid dermatitis (HP:0000976)2.63615608
35Mitral valve prolapse (HP:0001634)2.59751103
36Ankle contracture (HP:0006466)2.58253428
37Emphysema (HP:0002097)2.57823198
38Calcaneovalgus deformity (HP:0001848)2.52969615
39Gastrointestinal stroma tumor (HP:0100723)2.51841559
40Soft skin (HP:0000977)2.50887973
41Syringomyelia (HP:0003396)2.48641960
42Spinal cord lesions (HP:0100561)2.48641960
43Absent phalangeal crease (HP:0006109)2.44778936
44Distal lower limb muscle weakness (HP:0009053)2.42806005
45Vertebral compression fractures (HP:0002953)2.40550568
46Cervical subluxation (HP:0003308)2.40079747
47Vascular tortuosity (HP:0004948)2.39981119
48Rhabdomyolysis (HP:0003201)2.38129732
49Follicular hyperkeratosis (HP:0007502)2.37737865
50Recurrent abscess formation (HP:0002722)2.36235576
51Muscle fiber splitting (HP:0003555)2.35470276
52Limited hip movement (HP:0008800)2.34858600
53Myocardial infarction (HP:0001658)2.34566601
54Fragile skin (HP:0001030)2.33995823
55Right ventricular cardiomyopathy (HP:0011663)2.30713090
56Deformed tarsal bones (HP:0008119)2.30337808
57Myoglobinuria (HP:0002913)2.28521071
58Aneurysm (HP:0002617)2.27325613
59Autoimmune thrombocytopenia (HP:0001973)2.25645072
60Abnormality of dentin (HP:0010299)2.24515286
61Spinal rigidity (HP:0003306)2.23899409
62Sudden death (HP:0001699)2.23414338
63Arterial tortuosity (HP:0005116)2.20313162
64Difficulty running (HP:0009046)2.18095890
65Camptodactyly of toe (HP:0001836)2.18086244
66Hip contracture (HP:0003273)2.17210084
67Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.16698244
68Muscle fiber inclusion bodies (HP:0100299)2.15868837
69Spondylolisthesis (HP:0003302)2.15416100
70Complement deficiency (HP:0004431)2.14657564
71Wormian bones (HP:0002645)2.14633579
72Centrally nucleated skeletal muscle fibers (HP:0003687)2.14464273
73Cardiovascular calcification (HP:0011915)2.11564025
74Recurrent bacterial skin infections (HP:0005406)2.11308553
75Recurrent viral infections (HP:0004429)2.10494689
76Abnormality of the acetabulum (HP:0003170)2.09735652
77Hyporeflexia of lower limbs (HP:0002600)2.08587395
78Blue sclerae (HP:0000592)2.08362220
79Round ear (HP:0100830)2.08214100
80Ulnar bowing (HP:0003031)2.07567354
81Scapular winging (HP:0003691)2.06364000
82Hypoalphalipoproteinemia (HP:0003233)2.06045270
83Colitis (HP:0002583)2.05427269
84Malignant hyperthermia (HP:0002047)2.04503016
85Abnormality of the left ventricular outflow tract (HP:0011103)2.03646403
86Subaortic stenosis (HP:0001682)2.03646403
87Vasculitis (HP:0002633)2.00988004
88Genu recurvatum (HP:0002816)2.00740064
89Pulmonary artery stenosis (HP:0004415)1.99018233
90Mitral stenosis (HP:0001718)1.97548706
91Abnormal finger flexion creases (HP:0006143)1.96433860
92Bundle branch block (HP:0011710)1.96146265
93Elbow flexion contracture (HP:0002987)1.96120908
94Abnormality of the peritoneum (HP:0002585)1.96107890
95Mildly elevated creatine phosphokinase (HP:0008180)1.95870692
96Mitral regurgitation (HP:0001653)1.94753142
97Thick nail (HP:0001805)1.94124842
98Thin bony cortex (HP:0002753)1.93696478
99Abnormal delivery (HP:0001787)1.93017678
100Wide anterior fontanel (HP:0000260)1.92069848
101Hyperkalemia (HP:0002153)1.91975674
102Rimmed vacuoles (HP:0003805)1.91583672
103Recurrent bronchitis (HP:0002837)1.90492200
104Osteomyelitis (HP:0002754)1.89131275
105Ovoid vertebral bodies (HP:0003300)1.88748668
106Recurrent fungal infections (HP:0002841)1.88065956
107Striae distensae (HP:0001065)1.87528452
108Facial diplegia (HP:0001349)1.87517848
109Joint contractures involving the joints of the feet (HP:0100492)1.87269626
110Flexion contracture of toe (HP:0005830)1.87269626
111Myositis (HP:0100614)1.86895611
112Aortic regurgitation (HP:0001659)1.86796356
113Mediastinal lymphadenopathy (HP:0100721)1.86691862
114Rectal prolapse (HP:0002035)1.85787171
115Bicuspid aortic valve (HP:0001647)1.85652785
116Ventricular tachycardia (HP:0004756)1.85116754
117Restrictive lung disease (HP:0002091)1.84391174
118Distal lower limb amyotrophy (HP:0008944)1.83853477
119Pulmonary infiltrates (HP:0002113)1.83040766
120Periodontitis (HP:0000704)1.82874070
121Wrist flexion contracture (HP:0001239)1.82779796
122Lipoatrophy (HP:0100578)1.82630007
123Absent frontal sinuses (HP:0002688)1.82464315
124Infantile muscular hypotonia (HP:0008947)1.82455928
125Persistence of primary teeth (HP:0006335)1.81697785
126Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.80152988
127Short 4th metacarpal (HP:0010044)1.80152988
128Elevated erythrocyte sedimentation rate (HP:0003565)1.79868526
129Dilated cardiomyopathy (HP:0001644)1.77889577
130Nemaline bodies (HP:0003798)1.77294190
131Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.76691700
132Abnormality of the calf musculature (HP:0001430)1.76539640
133Osteoarthritis (HP:0002758)1.76387568
134Inflammation of the large intestine (HP:0002037)1.76140972
135Orchitis (HP:0100796)1.76124975
136Frequent falls (HP:0002359)1.75864072
137Viral hepatitis (HP:0006562)1.75544278
138Tibial bowing (HP:0002982)1.75465966
139Abnormality of the fingertips (HP:0001211)1.75291670
140Hyperextensible skin (HP:0000974)1.74325434
141Abnormality of complement system (HP:0005339)1.74240670
142Muscle stiffness (HP:0003552)1.74169394
143Joint laxity (HP:0001388)1.73412350
144Mesomelia (HP:0003027)1.72912317
145Biconcave vertebral bodies (HP:0004586)1.71521238
146Arterial thrombosis (HP:0004420)1.71349620
147Difficulty climbing stairs (HP:0003551)1.71081552
148Bladder diverticulum (HP:0000015)1.70955146
149Ectopia lentis (HP:0001083)1.70179229
150Myotonia (HP:0002486)1.70098038
151Hypoplastic ischia (HP:0003175)1.69917174
152Distal arthrogryposis (HP:0005684)1.69722009
153Abnormality of the ischium (HP:0003174)1.69657660
154Abnormality of the calcaneus (HP:0008364)1.69648422
155Coxa vara (HP:0002812)1.69471166
156Vascular calcification (HP:0004934)1.68239988
157Hydroxyprolinuria (HP:0003080)1.67033760
158Abnormality of proline metabolism (HP:0010907)1.67033760
159Subacute progressive viral hepatitis (HP:0006572)1.66838243

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN3.84147795
2MAP3K142.89102794
3PHKG12.63581823
4PHKG22.63581823
5ERN12.52562497
6MAP4K12.46804690
7AKT32.08260254
8TBK12.05006412
9PIK3CA2.04498902
10RIPK12.04429206
11TGFBR22.03983504
12DMPK2.02282241
13JAK11.96946277
14TYK21.96009312
15MAP3K101.90080109
16STK101.88541083
17TRIB31.77744710
18LRRK21.77335704
19JAK31.76547341
20LATS11.66848206
21IKBKB1.64711908
22RPS6KA41.64158250
23FRK1.62415080
24NEK91.62070435
25TIE11.59535385
26TRPM71.54662696
27OBSCN1.51902854
28LMTK21.47977322
29IRAK31.46481699
30CHUK1.44255428
31EPHA31.42974290
32DDR21.41696247
33STK31.40953643
34STK38L1.40143261
35NUAK11.39204805
36LATS21.36373376
37FGFR31.35496435
38PIK3CG1.31132362
39PDGFRA1.30173948
40MAP3K131.29967751
41LIMK11.29343439
42IKBKE1.23025164
43SIK11.22883014
44MAPKAPK31.22247916
45KIT1.22086108
46MYLK1.22023879
47CSK1.21825201
48CSF1R1.21399961
49RIPK41.20590896
50CDK121.19249191
51IRAK41.18429010
52FGFR41.17936854
53PTK61.17223827
54MAP2K31.16515312
55EPHB11.14894448
56PAK21.12814077
57ZAK1.07564106
58PKN21.03534604
59STK381.02793784
60MARK30.99595957
61HCK0.99508426
62MET0.99404349
63EPHB20.98893232
64ICK0.98224922
65BMX0.96745205
66BLK0.94042459
67TEC0.92366388
68MUSK0.91936278
69ZAP700.90835847
70TXK0.89463854
71STK240.89382505
72PDGFRB0.89113521
73KDR0.88793603
74MAP3K30.85084295
75CAMK1D0.83605395
76PRKG20.83215409
77MAPK120.81922120
78ITK0.81049107
79BTK0.80083752
80MARK10.80063821
81NTRK20.80059875
82NTRK10.79599602
83ERBB30.78779375
84PIM10.75821073
85PTK20.74262334
86CDK60.74014865
87PRKAA10.73774088
88MAPK70.72644384
89WNK40.70407425
90DYRK1B0.69148216
91MOS0.67423273
92FGFR10.66663637
93GRK70.65688810
94LCK0.65152976
95CAMK2G0.64552639
96SYK0.64140717
97NLK0.61865298
98PRKD10.61646035
99EEF2K0.61339096
100ROCK10.60761088
101ABL10.60450992
102PRKG10.60280623
103INSRR0.59569503
104TGFBR10.59390898
105PIM20.59248794
106SGK20.58942752
107SGK30.58813096
108INSR0.58712161
109EPHA20.58520940
110STK390.57169913
111PTK2B0.57167772
112CDC42BPA0.56800581
113FER0.56191628
114PDK20.55935585
115MST1R0.55803624
116MAP3K60.55443346
117MST40.55342736
118LYN0.54689064
119MELK0.54668652
120MAP2K10.54639686
121TESK10.54396410
122PAK30.53305653
123ILK0.53162444
124STK40.52768913
125MAPKAPK20.51819621
126RPS6KA20.50819487
127GSK3A0.50599000
128PDPK10.50549003
129MTOR0.49874170
130PRKCH0.47796046
131MAPK40.47706095
132PRKD20.46868526
133CAMK1G0.46175518
134CLK10.46113084
135SGK4940.45107808
136SGK2230.45107808
137MAP3K70.44285338
138EGFR0.43496570
139TYRO30.43043900
140CAMK10.42319841
141WNK10.42276714
142CAMK2D0.42218994
143ROCK20.41836750
144PRKCQ0.40941448
145PAK40.39732761
146ADRBK10.39394015
147PNCK0.38654153
148PRKAA20.38380307
149ERBB40.37947760
150FLT30.37549878
151RET0.36028579
152MAPK110.35687114
153MARK20.33618444
154ABL20.33350826
155MAPK150.31757524

Predicted pathways (KEGG)

RankGene SetZ-score
1Complement and coagulation cascades_Homo sapiens_hsa046102.99149868
2Leishmaniasis_Homo sapiens_hsa051402.64299416
3NF-kappa B signaling pathway_Homo sapiens_hsa040642.38867342
4B cell receptor signaling pathway_Homo sapiens_hsa046622.20768033
5Osteoclast differentiation_Homo sapiens_hsa043802.11538627
6Malaria_Homo sapiens_hsa051442.07201327
7Viral myocarditis_Homo sapiens_hsa054161.97604713
8Toxoplasmosis_Homo sapiens_hsa051451.94310911
9ECM-receptor interaction_Homo sapiens_hsa045121.93426002
10Primary immunodeficiency_Homo sapiens_hsa053401.89760483
11Toll-like receptor signaling pathway_Homo sapiens_hsa046201.87679490
12Hematopoietic cell lineage_Homo sapiens_hsa046401.87312127
13Focal adhesion_Homo sapiens_hsa045101.78852597
14Circadian rhythm_Homo sapiens_hsa047101.78643786
15Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.78501391
16Intestinal immune network for IgA production_Homo sapiens_hsa046721.78497799
17TNF signaling pathway_Homo sapiens_hsa046681.76687857
18AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.75342375
19Leukocyte transendothelial migration_Homo sapiens_hsa046701.74617024
20Small cell lung cancer_Homo sapiens_hsa052221.73466709
21Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.71730975
22Adherens junction_Homo sapiens_hsa045201.69614590
23Measles_Homo sapiens_hsa051621.68863792
24Vascular smooth muscle contraction_Homo sapiens_hsa042701.67897686
25NOD-like receptor signaling pathway_Homo sapiens_hsa046211.63389792
26Dilated cardiomyopathy_Homo sapiens_hsa054141.62562496
27Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.60351097
28Proteoglycans in cancer_Homo sapiens_hsa052051.57315724
29Shigellosis_Homo sapiens_hsa051311.51490242
30Amoebiasis_Homo sapiens_hsa051461.47593332
31Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.46771480
32PPAR signaling pathway_Homo sapiens_hsa033201.45124261
33Tuberculosis_Homo sapiens_hsa051521.44962912
34Antigen processing and presentation_Homo sapiens_hsa046121.42295411
35Salmonella infection_Homo sapiens_hsa051321.42126955
36RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.41934334
37Chronic myeloid leukemia_Homo sapiens_hsa052201.40811471
38Pertussis_Homo sapiens_hsa051331.39823988
39Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.38956118
40Graft-versus-host disease_Homo sapiens_hsa053321.35763440
41Allograft rejection_Homo sapiens_hsa053301.33694167
42Apoptosis_Homo sapiens_hsa042101.32290008
43Fat digestion and absorption_Homo sapiens_hsa049751.31450183
44Legionellosis_Homo sapiens_hsa051341.30701339
45Influenza A_Homo sapiens_hsa051641.29210899
46MicroRNAs in cancer_Homo sapiens_hsa052061.29145128
47Platelet activation_Homo sapiens_hsa046111.28752472
48Jak-STAT signaling pathway_Homo sapiens_hsa046301.27239970
49Fatty acid biosynthesis_Homo sapiens_hsa000611.26073691
50Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.25036798
51cGMP-PKG signaling pathway_Homo sapiens_hsa040221.23490168
52Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.23235190
53Herpes simplex infection_Homo sapiens_hsa051681.22732327
54Glucagon signaling pathway_Homo sapiens_hsa049221.20033695
55Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.17825967
56Fatty acid degradation_Homo sapiens_hsa000711.16943996
57Hepatitis B_Homo sapiens_hsa051611.16344974
58Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.15237074
59Regulation of actin cytoskeleton_Homo sapiens_hsa048101.14829491
60Pancreatic cancer_Homo sapiens_hsa052121.11187360
61T cell receptor signaling pathway_Homo sapiens_hsa046601.09956690
62Chemokine signaling pathway_Homo sapiens_hsa040621.07999000
63Starch and sucrose metabolism_Homo sapiens_hsa005001.07017395
64Bile secretion_Homo sapiens_hsa049761.04921710
65Staphylococcus aureus infection_Homo sapiens_hsa051501.03668343
66Oxytocin signaling pathway_Homo sapiens_hsa049211.03478022
67Arginine biosynthesis_Homo sapiens_hsa002201.03277262
682-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.01964681
69Thyroid hormone synthesis_Homo sapiens_hsa049181.01161531
70Insulin signaling pathway_Homo sapiens_hsa049101.00067980
71p53 signaling pathway_Homo sapiens_hsa041150.99905634
72Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.99889180
73Renin secretion_Homo sapiens_hsa049240.99250202
74Calcium signaling pathway_Homo sapiens_hsa040200.98529753
75Phenylalanine metabolism_Homo sapiens_hsa003600.96832150
76Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.96828390
77TGF-beta signaling pathway_Homo sapiens_hsa043500.96407107
78Renin-angiotensin system_Homo sapiens_hsa046140.96364928
79Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.95694500
80HTLV-I infection_Homo sapiens_hsa051660.93435307
81Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.92041635
82Arginine and proline metabolism_Homo sapiens_hsa003300.87472246
83Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.87212285
84Acute myeloid leukemia_Homo sapiens_hsa052210.85937776
85African trypanosomiasis_Homo sapiens_hsa051430.85507313
86Cardiac muscle contraction_Homo sapiens_hsa042600.85428538
87Transcriptional misregulation in cancer_Homo sapiens_hsa052020.84850633
88Pancreatic secretion_Homo sapiens_hsa049720.84334888
89Hepatitis C_Homo sapiens_hsa051600.83015992
90Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.82323003
91PI3K-Akt signaling pathway_Homo sapiens_hsa041510.81251977
92ABC transporters_Homo sapiens_hsa020100.80955507
93Prostate cancer_Homo sapiens_hsa052150.80885316
94AMPK signaling pathway_Homo sapiens_hsa041520.79998122
95Neurotrophin signaling pathway_Homo sapiens_hsa047220.79230326
96Insulin resistance_Homo sapiens_hsa049310.78755907
97Gastric acid secretion_Homo sapiens_hsa049710.77610460
98Histidine metabolism_Homo sapiens_hsa003400.77558534
99Pathways in cancer_Homo sapiens_hsa052000.77220130
100Viral carcinogenesis_Homo sapiens_hsa052030.76732962
101Dorso-ventral axis formation_Homo sapiens_hsa043200.76517384
102Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.76503236
103Autoimmune thyroid disease_Homo sapiens_hsa053200.76219427
104HIF-1 signaling pathway_Homo sapiens_hsa040660.76063038
105Protein digestion and absorption_Homo sapiens_hsa049740.75637738
106Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.74987894
107GnRH signaling pathway_Homo sapiens_hsa049120.72326274
108Other glycan degradation_Homo sapiens_hsa005110.71503947
109Aldosterone synthesis and secretion_Homo sapiens_hsa049250.71433754
110Sulfur metabolism_Homo sapiens_hsa009200.70041684
111FoxO signaling pathway_Homo sapiens_hsa040680.69836213
112Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.69831916
113Rheumatoid arthritis_Homo sapiens_hsa053230.67979878
114Ovarian steroidogenesis_Homo sapiens_hsa049130.67405314
115Epstein-Barr virus infection_Homo sapiens_hsa051690.66800410
116Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.66618387
117Notch signaling pathway_Homo sapiens_hsa043300.65761035
118Gap junction_Homo sapiens_hsa045400.65493414
119Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.64604300
120Asthma_Homo sapiens_hsa053100.63013185
121Longevity regulating pathway - mammal_Homo sapiens_hsa042110.62481969
122Adipocytokine signaling pathway_Homo sapiens_hsa049200.61648670
123Rap1 signaling pathway_Homo sapiens_hsa040150.61535184
124Fatty acid metabolism_Homo sapiens_hsa012120.61122502
125Phagosome_Homo sapiens_hsa041450.59946932
126VEGF signaling pathway_Homo sapiens_hsa043700.59649648
127Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.59538324
128Renal cell carcinoma_Homo sapiens_hsa052110.58424766
129Prolactin signaling pathway_Homo sapiens_hsa049170.57602756
130Melanoma_Homo sapiens_hsa052180.56313340
131Mineral absorption_Homo sapiens_hsa049780.56223641
132Bladder cancer_Homo sapiens_hsa052190.55791693
133MAPK signaling pathway_Homo sapiens_hsa040100.55616125
134Salivary secretion_Homo sapiens_hsa049700.55253938
135Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.54768236
136Hippo signaling pathway_Homo sapiens_hsa043900.54533589
137Glycosaminoglycan degradation_Homo sapiens_hsa005310.54457358
138Hedgehog signaling pathway_Homo sapiens_hsa043400.53195974
139Melanogenesis_Homo sapiens_hsa049160.51870472
140Axon guidance_Homo sapiens_hsa043600.51125878
141Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.50963169
142Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.50899771
143Insulin secretion_Homo sapiens_hsa049110.50835459
144cAMP signaling pathway_Homo sapiens_hsa040240.49929532
145Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.48778011
146Endocytosis_Homo sapiens_hsa041440.47881320
147Estrogen signaling pathway_Homo sapiens_hsa049150.47336900
148Colorectal cancer_Homo sapiens_hsa052100.47324594
149Basal cell carcinoma_Homo sapiens_hsa052170.46541131
150Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.46258399
151Glioma_Homo sapiens_hsa052140.46160350
152Olfactory transduction_Homo sapiens_hsa047400.45691942
153Prion diseases_Homo sapiens_hsa050200.45266853
154Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.45113176
155Tyrosine metabolism_Homo sapiens_hsa003500.44928424
156Tight junction_Homo sapiens_hsa045300.43867183
157Fructose and mannose metabolism_Homo sapiens_hsa000510.43551061
158Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.42966951
159Phospholipase D signaling pathway_Homo sapiens_hsa040720.41975166
160alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.41691053
161Vitamin digestion and absorption_Homo sapiens_hsa049770.41293499
162Lysosome_Homo sapiens_hsa041420.38829442
163mTOR signaling pathway_Homo sapiens_hsa041500.38822500
164Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.38496971
165Primary bile acid biosynthesis_Homo sapiens_hsa001200.37888775
166Thyroid hormone signaling pathway_Homo sapiens_hsa049190.37353532
167Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.36761393
168Lysine degradation_Homo sapiens_hsa003100.36337000

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »