FLI1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.39358118
2definitive hemopoiesis (GO:0060216)5.07985712
3positive regulation of gamma-delta T cell activation (GO:0046645)4.85229294
4regulation of B cell receptor signaling pathway (GO:0050855)4.68558234
5positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.53812998
6antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.29254951
7antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.29254951
8ribosomal small subunit assembly (GO:0000028)4.26822657
9detection of other organism (GO:0098543)4.18493616
10negative regulation of phagocytosis (GO:0050765)4.16319492
11positive thymic T cell selection (GO:0045059)4.08768116
12antigen processing and presentation of endogenous antigen (GO:0019883)4.06981627
13detection of bacterium (GO:0016045)3.97383435
14positive regulation of B cell differentiation (GO:0045579)3.92382265
15mast cell activation (GO:0045576)3.81741112
16macrophage activation involved in immune response (GO:0002281)3.81417718
17negative regulation of lymphocyte mediated immunity (GO:0002707)3.80687470
18positive T cell selection (GO:0043368)3.77600049
19angiogenesis involved in wound healing (GO:0060055)3.74742318
20negative regulation of interleukin-12 production (GO:0032695)3.67393270
21negative regulation of T cell mediated immunity (GO:0002710)3.64619849
22B cell receptor signaling pathway (GO:0050853)3.60110988
23Arp2/3 complex-mediated actin nucleation (GO:0034314)3.59180085
24T cell selection (GO:0045058)3.58967873
25microglial cell activation (GO:0001774)3.51713963
26tolerance induction (GO:0002507)3.51467204
27detection of external biotic stimulus (GO:0098581)3.49075315
28regulation of gamma-delta T cell differentiation (GO:0045586)3.48152702
29response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.44737749
30response to host immune response (GO:0052572)3.44737749
31positive regulation of mast cell activation (GO:0033005)3.44709243
32granulocyte activation (GO:0036230)3.44684974
33regulation of mast cell degranulation (GO:0043304)3.43414286
34negative regulation of leukocyte mediated immunity (GO:0002704)3.43406995
35* megakaryocyte development (GO:0035855)3.42671435
36regulation of B cell differentiation (GO:0045577)3.38451663
37thymic T cell selection (GO:0045061)3.37600583
38response to interferon-beta (GO:0035456)3.37507250
39neutrophil activation involved in immune response (GO:0002283)3.36656751
40negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.34316681
41positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.33870032
42interferon-gamma production (GO:0032609)3.30322080
43regulation of gamma-delta T cell activation (GO:0046643)3.30161403
44platelet dense granule organization (GO:0060155)3.28395083
45regulation of alpha-beta T cell proliferation (GO:0046640)3.26940190
46positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.24601477
47positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.23827379
48detection of molecule of bacterial origin (GO:0032490)3.23746025
49cellular extravasation (GO:0045123)3.23669906
50regulation of mast cell activation involved in immune response (GO:0033006)3.21243481
51histamine secretion (GO:0001821)3.20713280
52regulation of tolerance induction (GO:0002643)3.19923938
53myeloid dendritic cell activation (GO:0001773)3.18397874
54regulation of T cell tolerance induction (GO:0002664)3.17844488
55response to host (GO:0075136)3.15448301
56response to host defenses (GO:0052200)3.15448301
57response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.15448301
58regulation of interferon-beta biosynthetic process (GO:0045357)3.14463119
59regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.14196060
60immunoglobulin mediated immune response (GO:0016064)3.11885858
61macrophage activation (GO:0042116)3.11685990
62regulation of myeloid leukocyte mediated immunity (GO:0002886)3.09785474
63regulation of regulatory T cell differentiation (GO:0045589)3.09008629
64regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.08491246
65detection of biotic stimulus (GO:0009595)3.06282348
66negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.04453505
67negative regulation of T-helper cell differentiation (GO:0045623)3.04453505
68regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.04289167
69regulation of natural killer cell mediated immunity (GO:0002715)3.04289167
70mature B cell differentiation involved in immune response (GO:0002313)3.04133635
71regulation of granulocyte differentiation (GO:0030852)3.03503971
72mast cell degranulation (GO:0043303)3.03180555
73mast cell activation involved in immune response (GO:0002279)3.03180555
74activated T cell proliferation (GO:0050798)3.03091290
75antigen processing and presentation via MHC class Ib (GO:0002475)3.00180352
76leukocyte migration involved in inflammatory response (GO:0002523)2.99145705
77regulation of leukocyte degranulation (GO:0043300)2.97822088
78regulation of T cell mediated cytotoxicity (GO:0001914)2.97718163
79mucosal-associated lymphoid tissue development (GO:0048537)2.97627029
80Peyers patch development (GO:0048541)2.97627029
81cellular response to zinc ion (GO:0071294)2.97614425
82T cell migration (GO:0072678)2.97471895
83antigen receptor-mediated signaling pathway (GO:0050851)2.92525987
84positive regulation of macrophage differentiation (GO:0045651)2.92470342
85response to protozoan (GO:0001562)2.91922598
86positive regulation of mast cell activation involved in immune response (GO:0033008)2.91335060
87positive regulation of mast cell degranulation (GO:0043306)2.91335060
88defense response to protozoan (GO:0042832)2.90661382
89positive regulation of T cell mediated cytotoxicity (GO:0001916)2.90627559
90histamine transport (GO:0051608)2.89400541
91pinocytosis (GO:0006907)2.89353341
92T cell homeostasis (GO:0043029)2.88683595
93mature B cell differentiation (GO:0002335)2.88612187
94leukocyte aggregation (GO:0070486)2.87418869
95germinal center formation (GO:0002467)2.87140189
96positive regulation of interferon-alpha production (GO:0032727)2.86017962
97response to type I interferon (GO:0034340)2.85445853
98embryonic hemopoiesis (GO:0035162)2.82961986
99regulation of T cell receptor signaling pathway (GO:0050856)2.81655653
100type I interferon signaling pathway (GO:0060337)2.81557552
101cellular response to type I interferon (GO:0071357)2.81557552
102lymphocyte homeostasis (GO:0002260)2.81128851
103production of molecular mediator involved in inflammatory response (GO:0002532)2.79238304
104myeloid cell activation involved in immune response (GO:0002275)2.79230353
105respiratory burst (GO:0045730)2.77909671
106cellular response to interferon-beta (GO:0035458)2.77100159
107negative regulation of nitric oxide biosynthetic process (GO:0045019)2.77035712
108regulation of interferon-alpha production (GO:0032647)2.74712477
109neutrophil activation (GO:0042119)2.73186255
110negative regulation of erythrocyte differentiation (GO:0045647)2.72147677
111interferon-gamma-mediated signaling pathway (GO:0060333)2.71540584
112modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.71401955
113positive regulation by organism of defense response of other organism involved in symbiotic interact2.71401955
114modulation by symbiont of host immune response (GO:0052553)2.71401955
115positive regulation by symbiont of host defense response (GO:0052509)2.71401955
116modulation by symbiont of host defense response (GO:0052031)2.71401955
117modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.71401955
118dendritic cell chemotaxis (GO:0002407)2.70446763
119lymph node development (GO:0048535)2.70445486
120negative T cell selection (GO:0043383)2.70271091
121response to interleukin-15 (GO:0070672)2.70126102
122regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.69581667
123negative thymic T cell selection (GO:0045060)2.69185660
124response to interferon-alpha (GO:0035455)2.68965967
125B cell homeostasis (GO:0001782)2.67264975
126regulation of interleukin-12 biosynthetic process (GO:0045075)2.66651104
127secretory granule organization (GO:0033363)2.65258681
128actin nucleation (GO:0045010)2.64909631
129negative regulation of granulocyte differentiation (GO:0030853)2.63968624
130positive regulation of granulocyte differentiation (GO:0030854)2.63715883
131B cell mediated immunity (GO:0019724)2.63208848
132phagocytosis, engulfment (GO:0006911)2.62779993
133myeloid leukocyte activation (GO:0002274)2.61859071
134regulation of mast cell activation (GO:0033003)2.60192988
135negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.58814761
136negative regulation of cell killing (GO:0031342)2.58814761
137regulation of erythrocyte differentiation (GO:0045646)2.57767221
138regulation of necroptotic process (GO:0060544)2.56889616
139leukocyte homeostasis (GO:0001776)2.56814965
140leukocyte degranulation (GO:0043299)2.56736050
141dendritic cell migration (GO:0036336)2.55216574
142cellular response to interleukin-15 (GO:0071350)2.54492398
143response to muramyl dipeptide (GO:0032495)2.53640989
144telomere maintenance via semi-conservative replication (GO:0032201)2.52837106
145response to peptidoglycan (GO:0032494)2.51926373
146positive regulation of antigen processing and presentation (GO:0002579)2.51902190
147hepatocyte apoptotic process (GO:0097284)2.50535094
148myeloid dendritic cell differentiation (GO:0043011)2.48743096
149B cell differentiation (GO:0030183)2.48630828
150regulation of response to interferon-gamma (GO:0060330)2.48608194

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.88996425
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.69585089
3IRF8_22096565_ChIP-ChIP_GC-B_Human4.67411231
4BP1_19119308_ChIP-ChIP_Hs578T_Human4.62686473
5* STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.84489124
6* SCL_19346495_ChIP-Seq_HPC-7_Human3.77514780
7* MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.74311711
8IRF8_21731497_ChIP-ChIP_J774_Mouse3.70481087
9IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.68741411
10SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.11870445
11MYB_21317192_ChIP-Seq_ERMYB_Mouse2.88355367
12SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.83806159
13* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.71793849
14IRF8_27001747_Chip-Seq_BMDM_Mouse2.70096066
15RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.66868137
16ELF1_17652178_ChIP-ChIP_JURKAT_Human2.60115398
17EGR1_19374776_ChIP-ChIP_THP-1_Human2.58081520
18* STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.56433152
19* SPI1_23547873_ChIP-Seq_NB4_Human2.51074156
20STAT4_19710469_ChIP-ChIP_TH1__Mouse2.48838269
21* IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.48793748
22NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.48622347
23* RUNX_20019798_ChIP-Seq_JUKART_Human2.34566335
24* MYB_26560356_Chip-Seq_TH2_Human2.28771440
25FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.26180775
26* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.20348680
27NOTCH1_21737748_ChIP-Seq_TLL_Human2.15905889
28* MYC_22102868_ChIP-Seq_BL_Human2.13714597
29VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.10634586
30TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.09736551
31* MYB_26560356_Chip-Seq_TH1_Human2.02007401
32* ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.01775494
33VDR_21846776_ChIP-Seq_THP-1_Human2.00057150
34* RUNX1_22412390_ChIP-Seq_EML_Mouse1.98965590
35* MAF_26560356_Chip-Seq_TH1_Human1.96334508
36LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.95087799
37MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.88614704
38E2F4_17652178_ChIP-ChIP_JURKAT_Human1.87923524
39HOXB4_20404135_ChIP-ChIP_EML_Mouse1.83138011
40* VDR_24763502_ChIP-Seq_THP-1_Human1.82324480
41LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.81974731
42NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.80279134
43BRD4_27068464_Chip-Seq_AML-cells_Mouse1.78060032
44SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.73815176
45GATA1_22025678_ChIP-Seq_K562_Human1.66710986
46* UTX_26944678_Chip-Seq_JUKART_Human1.64801248
47ERG_20887958_ChIP-Seq_HPC-7_Mouse1.63121698
48HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.60046683
49SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.59666583
50* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.58964500
51GATA2_22383799_ChIP-Seq_G1ME_Mouse1.58776137
52SPI1_23127762_ChIP-Seq_K562_Human1.56329482
53* GATA2_21666600_ChIP-Seq_HMVEC_Human1.54084440
54* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.52574468
55GATA1_19941826_ChIP-Seq_K562_Human1.51529569
56GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.51070082
57* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.50541259
58PU_27001747_Chip-Seq_BMDM_Mouse1.49235397
59GATA1_22383799_ChIP-Seq_G1ME_Mouse1.42629703
60* TCF7_22412390_ChIP-Seq_EML_Mouse1.41117191
61GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.36306644
62ELK1_19687146_ChIP-ChIP_HELA_Human1.34461693
63* KDM2B_26808549_Chip-Seq_DND41_Human1.33928370
64* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.33690959
65EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.32594970
66Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.30180789
67FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.29726035
68FOXM1_23109430_ChIP-Seq_U2OS_Human1.26178957
69* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.25082590
70* GATA3_27048872_Chip-Seq_THYMUS_Human1.23546260
71NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.22796857
72VDR_23849224_ChIP-Seq_CD4+_Human1.20935963
73RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.20156237
74FOXP3_21729870_ChIP-Seq_TREG_Human1.16647923
75CIITA_25753668_ChIP-Seq_RAJI_Human1.16040773
76GATA2_19941826_ChIP-Seq_K562_Human1.13418867
77PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.12562169
78CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.11236903
79PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.10986857
80PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.10582153
81* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.10494603
82VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.10239669
83MAF_26560356_Chip-Seq_TH2_Human1.09336002
84E2F1_21310950_ChIP-Seq_MCF-7_Human1.08807001
85* RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.07991402
86FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.07414818
87* GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.05484164
88EST1_17652178_ChIP-ChIP_JURKAT_Human1.03692658
89NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.03458119
90GATA3_26560356_Chip-Seq_TH2_Human1.03384494
91STAT6_21828071_ChIP-Seq_BEAS2B_Human1.03187330
92* GATA1_19941827_ChIP-Seq_MEL_Mouse1.02368971
93STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.01426803
94CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.01096332
95STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.99039851
96IKZF1_21737484_ChIP-ChIP_HCT116_Human0.97930772
97CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.97686605
98MYC_18555785_ChIP-Seq_MESCs_Mouse0.94278614
99* KDM2B_26808549_Chip-Seq_JURKAT_Human0.93194532
100CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.91185922
101RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.91034366
102* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.90260521
103TP63_19390658_ChIP-ChIP_HaCaT_Human0.89808155
104NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.88604712
105VDR_24787735_ChIP-Seq_THP-1_Human0.86856376
106SPI1_20517297_ChIP-Seq_HL60_Human0.85944821
107SMAD_19615063_ChIP-ChIP_OVARY_Human0.85799689
108BCL6_27268052_Chip-Seq_Bcells_Human0.85648445
109PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.85159120
110CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.85144375
111* GATA1_19941827_ChIP-Seq_MEL86_Mouse0.84703019
112ETS1_22383799_ChIP-Seq_G1ME_Mouse0.83247951
113NCOR1_26117541_ChIP-Seq_K562_Human0.82204262
114SRF_21415370_ChIP-Seq_HL-1_Mouse0.82055225
115PU.1_20513432_ChIP-Seq_Bcells_Mouse0.81596260
116* ELK3_25401928_ChIP-Seq_HUVEC_Human0.80583726
117KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.80251078
118GABP_17652178_ChIP-ChIP_JURKAT_Human0.79279090
119* KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.79129188
120SMRT_27268052_Chip-Seq_Bcells_Human0.78789762
121PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.78664192
122MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.78052643
123* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.77189632
124P300_27268052_Chip-Seq_Bcells_Human0.69679541
125BCOR_27268052_Chip-Seq_Bcells_Human0.69265875

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation3.88176222
2MP0002396_abnormal_hematopoietic_system3.41493805
3MP0003724_increased_susceptibility_to3.32609541
4MP0005671_abnormal_response_to3.22532237
5MP0009785_altered_susceptibility_to2.82063160
6MP0003763_abnormal_thymus_physiology2.64282987
7MP0002148_abnormal_hypersensitivity_rea2.61558735
8* MP0001800_abnormal_humoral_immune2.60147172
9MP0005464_abnormal_platelet_physiology2.55504427
10MP0005000_abnormal_immune_tolerance2.49494412
11* MP0002452_abnormal_antigen_presenting2.47394048
12MP0004808_abnormal_hematopoietic_stem2.43421314
13MP0002166_altered_tumor_susceptibility2.42148574
14MP0000685_abnormal_immune_system2.41524886
15MP0002419_abnormal_innate_immunity2.40944149
16* MP0002420_abnormal_adaptive_immunity2.39959091
17MP0005025_abnormal_response_to2.39663502
18* MP0001819_abnormal_immune_cell2.37759768
19* MP0002723_abnormal_immune_serum2.32038009
20MP0003436_decreased_susceptibility_to2.30055957
21* MP0002398_abnormal_bone_marrow2.29098643
22MP0001790_abnormal_immune_system2.23082894
23MP0005387_immune_system_phenotype2.23082894
24MP0000465_gastrointestinal_hemorrhage2.21018789
25MP0001545_abnormal_hematopoietic_system2.14443067
26MP0005397_hematopoietic_system_phenotyp2.14443067
27MP0005174_abnormal_tail_pigmentation1.98234963
28* MP0000716_abnormal_immune_system1.98169301
29* MP0000689_abnormal_spleen_morphology1.93434590
30MP0009333_abnormal_splenocyte_physiolog1.90921500
31MP0002405_respiratory_system_inflammati1.89741340
32MP0001879_abnormal_lymphatic_vessel1.87363640
33MP0002006_tumorigenesis1.86509257
34MP0010155_abnormal_intestine_physiology1.84714976
35* MP0002722_abnormal_immune_system1.83681088
36MP0001853_heart_inflammation1.79599176
37* MP0002429_abnormal_blood_cell1.78359177
38MP0004147_increased_porphyrin_level1.71901596
39MP0001873_stomach_inflammation1.66877588
40MP0003828_pulmonary_edema1.60460990
41MP0005075_abnormal_melanosome_morpholog1.59830805
42MP0008057_abnormal_DNA_replication1.59016554
43MP0009278_abnormal_bone_marrow1.58478684
44MP0000490_abnormal_crypts_of1.56343071
45MP0003303_peritoneal_inflammation1.55582938
46MP0001845_abnormal_inflammatory_respons1.52571348
47* MP0000703_abnormal_thymus_morphology1.49022965
48MP0010368_abnormal_lymphatic_system1.46073276
49MP0006082_CNS_inflammation1.44116824
50MP0008007_abnormal_cellular_replicative1.42059213
51MP0000015_abnormal_ear_pigmentation1.41984402
52MP0000343_altered_response_to1.40860554
53MP0001533_abnormal_skeleton_physiology1.32008056
54MP0008260_abnormal_autophagy1.31461298
55MP0000858_altered_metastatic_potential1.28337619
56MP0002095_abnormal_skin_pigmentation1.27478846
57MP0003191_abnormal_cellular_cholesterol1.27148676
58MP0003943_abnormal_hepatobiliary_system1.25708591
59MP0003300_gastrointestinal_ulcer1.24050340
60MP0010094_abnormal_chromosome_stability1.23542171
61MP0003866_abnormal_defecation1.20840220
62MP0005167_abnormal_blood-brain_barrier1.18287864
63MP0005409_darkened_coat_color1.16225617
64MP0008469_abnormal_protein_level1.15458828
65MP0008004_abnormal_stomach_pH1.14720443
66MP0003693_abnormal_embryo_hatching1.11869441
67MP0001851_eye_inflammation1.09662589
68MP0002009_preneoplasia1.09084303
69MP0008058_abnormal_DNA_repair1.07811711
70MP0004381_abnormal_hair_follicle1.06579282
71MP0002138_abnormal_hepatobiliary_system1.06312519
72MP0003448_altered_tumor_morphology1.06048202
73MP0009697_abnormal_copulation1.03953346
74MP0003077_abnormal_cell_cycle1.01479118
75MP0004947_skin_inflammation1.00448777
76MP0004510_myositis1.00383807
77MP0009764_decreased_sensitivity_to0.98489411
78MP0002132_abnormal_respiratory_system0.97318752
79* MP0000249_abnormal_blood_vessel0.95933889
80* MP0002019_abnormal_tumor_incidence0.94081870
81MP0004130_abnormal_muscle_cell0.93869047
82MP0003567_abnormal_fetal_cardiomyocyte0.92204122
83MP0005058_abnormal_lysosome_morphology0.91070388
84MP0005166_decreased_susceptibility_to0.88551850
85MP0005164_abnormal_response_to0.88300858
86MP0003172_abnormal_lysosome_physiology0.86261988
87MP0002933_joint_inflammation0.84748786
88MP0002877_abnormal_melanocyte_morpholog0.81154913
89MP0004484_altered_response_of0.80806934
90MP0010307_abnormal_tumor_latency0.79461550
91MP0003111_abnormal_nucleus_morphology0.78397921
92* MP0000767_abnormal_smooth_muscle0.76893388
93MP0001986_abnormal_taste_sensitivity0.76504557
94MP0003656_abnormal_erythrocyte_physiolo0.75500100
95MP0002998_abnormal_bone_remodeling0.74368287
96MP0005451_abnormal_body_composition0.74292639
97MP0005310_abnormal_salivary_gland0.71950963
98MP0009763_increased_sensitivity_to0.69413164
99MP0003690_abnormal_glial_cell0.69346967
100MP0003795_abnormal_bone_structure0.68282102
101MP0009765_abnormal_xenobiotic_induced0.68069425
102MP0003045_fibrosis0.68034066
103MP0009379_abnormal_foot_pigmentation0.67529967
104MP0005084_abnormal_gallbladder_morpholo0.66960665
105MP0004782_abnormal_surfactant_physiolog0.66036576
106MP0004883_abnormal_blood_vessel0.65711780
107MP0001663_abnormal_digestive_system0.65165725
108MP0010352_gastrointestinal_tract_polyps0.64822129
109MP0000313_abnormal_cell_death0.64436611
110MP0005390_skeleton_phenotype0.62589954
111MP0003075_altered_response_to0.62283020
112MP0003183_abnormal_peptide_metabolism0.59686585
113MP0002277_abnormal_respiratory_mucosa0.58419023
114MP0001191_abnormal_skin_condition0.56543340
115MP0001188_hyperpigmentation0.55725258
116MP0003091_abnormal_cell_migration0.53680047
117MP0008874_decreased_physiological_sensi0.51324090
118MP0000604_amyloidosis0.49976000
119MP0005165_increased_susceptibility_to0.46656963
120MP0002133_abnormal_respiratory_system0.46486851
121MP0005388_respiratory_system_phenotype0.46486851
122MP0005381_digestive/alimentary_phenotyp0.44309408

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)4.76518417
2Myositis (HP:0100614)4.65754232
3Recurrent bacterial skin infections (HP:0005406)4.11913266
4Thrombocytosis (HP:0001894)4.05158165
5Prolonged bleeding time (HP:0003010)4.02519474
6IgM deficiency (HP:0002850)4.02318491
7Elevated erythrocyte sedimentation rate (HP:0003565)3.80436177
8Petechiae (HP:0000967)3.77659653
9Spontaneous hematomas (HP:0007420)3.73961246
10Recurrent viral infections (HP:0004429)3.64859971
11Gastrointestinal infarctions (HP:0005244)3.59058135
12Eczematoid dermatitis (HP:0000976)3.58319408
13Orchitis (HP:0100796)3.53276294
14Retrobulbar optic neuritis (HP:0100654)3.51548032
15Optic neuritis (HP:0100653)3.51548032
16Meningitis (HP:0001287)3.42186496
17Chronic otitis media (HP:0000389)3.39686013
18Recurrent fungal infections (HP:0002841)3.39323636
19Agammaglobulinemia (HP:0004432)3.27425868
20Cellulitis (HP:0100658)3.26623589
21Abnormal delayed hypersensitivity skin test (HP:0002963)3.17530830
22Epistaxis (HP:0000421)3.14730299
23Thyroiditis (HP:0100646)3.09178378
24Colitis (HP:0002583)3.07824829
25Inflammation of the large intestine (HP:0002037)3.05894022
26Autoimmune thrombocytopenia (HP:0001973)3.02242589
27B lymphocytopenia (HP:0010976)3.01827006
28Abnormality of B cell number (HP:0010975)3.01827006
29Mediastinal lymphadenopathy (HP:0100721)2.98230435
30Abnormality of T cell physiology (HP:0011840)2.96518428
31Obstructive lung disease (HP:0006536)2.93820846
32Chronic obstructive pulmonary disease (HP:0006510)2.93820846
33Panhypogammaglobulinemia (HP:0003139)2.93465186
34Recurrent bronchitis (HP:0002837)2.92068266
35Abnormality of T cells (HP:0002843)2.92025656
36Abnormality of the prostate (HP:0008775)2.90736675
37Gastrointestinal inflammation (HP:0004386)2.89775272
38Recurrent skin infections (HP:0001581)2.89570591
39Urticaria (HP:0001025)2.88301096
40Keratoconjunctivitis sicca (HP:0001097)2.80844925
41Gingivitis (HP:0000230)2.76549050
42Arterial thrombosis (HP:0004420)2.75762016
43Aplastic anemia (HP:0001915)2.74094649
44Vasculitis (HP:0002633)2.73520055
45IgG deficiency (HP:0004315)2.71612451
46Encephalitis (HP:0002383)2.71520570
47Hematochezia (HP:0002573)2.71280092
48T lymphocytopenia (HP:0005403)2.70233608
49Chronic mucocutaneous candidiasis (HP:0002728)2.69186857
50Recurrent cutaneous fungal infections (HP:0011370)2.69186857
51Reduced antithrombin III activity (HP:0001976)2.68872741
52Increased IgM level (HP:0003496)2.67949140
53Abnormal platelet function (HP:0011869)2.67751964
54Impaired platelet aggregation (HP:0003540)2.67751964
55Abnormality of T cell number (HP:0011839)2.64036782
56Lymphopenia (HP:0001888)2.58877985
57Abnormal platelet volume (HP:0011876)2.55698370
58Reticulocytopenia (HP:0001896)2.53585578
59Keratoconjunctivitis (HP:0001096)2.52187164
60Abnormality of the fingertips (HP:0001211)2.51608206
61Eosinophilia (HP:0001880)2.51378811
62Severe combined immunodeficiency (HP:0004430)2.48171886
63Abnormality of cells of the lymphoid lineage (HP:0012140)2.47395833
64Granulocytopenia (HP:0001913)2.47259826
65Abnormality of macrophages (HP:0004311)2.47136836
66Leukocytosis (HP:0001974)2.46398599
67Abnormality of eosinophils (HP:0001879)2.45689834
68Hemoptysis (HP:0002105)2.42464419
69Pulmonary infiltrates (HP:0002113)2.41828300
70Type I transferrin isoform profile (HP:0003642)2.39167911
71Hypochromic anemia (HP:0001931)2.37565638
72Purpura (HP:0000979)2.37471796
73Abnormality of the nasal mucosa (HP:0000433)2.34664418
74Autoimmune hemolytic anemia (HP:0001890)2.34252794
75Acute myeloid leukemia (HP:0004808)2.33854221
76Recurrent gram-negative bacterial infections (HP:0005420)2.33057607
77Hypochromic microcytic anemia (HP:0004840)2.29554829
78Episodic fever (HP:0001954)2.29544589
79Hypergammaglobulinemia (HP:0010702)2.28953624
80Gingival bleeding (HP:0000225)2.28405834
81Lymphoma (HP:0002665)2.27538587
82Gastrointestinal stroma tumor (HP:0100723)2.27514646
83Abnormal number of erythroid precursors (HP:0012131)2.25795822
84Periodontitis (HP:0000704)2.25504371
85Chronic diarrhea (HP:0002028)2.24182232
86Osteomyelitis (HP:0002754)2.23899887
87Chest pain (HP:0100749)2.23164239
88Verrucae (HP:0200043)2.23029778
89Papilloma (HP:0012740)2.23029778
90IgA deficiency (HP:0002720)2.19593701
91Anorexia (HP:0002039)2.17410492
92Vertigo (HP:0002321)2.16702489
93Vacuolated lymphocytes (HP:0001922)2.16102215
94Abnormality of cells of the erythroid lineage (HP:0012130)2.15955928
95Recurrent pneumonia (HP:0006532)2.15524716
96Gangrene (HP:0100758)2.15200180
97Combined immunodeficiency (HP:0005387)2.14844028
98Amaurosis fugax (HP:0100576)2.13895160
99Pustule (HP:0200039)2.12995924
100Stomatitis (HP:0010280)2.09826955
101Myelodysplasia (HP:0002863)2.07489132
102Pulmonary embolism (HP:0002204)2.07146084
103Peritonitis (HP:0002586)2.06990561
104Viral hepatitis (HP:0006562)2.06959604
105Sepsis (HP:0100806)2.06930428
106Increased mean platelet volume (HP:0011877)2.06928607
107Thrombophlebitis (HP:0004418)2.06032537
108Menorrhagia (HP:0000132)2.05636170
109Increased IgE level (HP:0003212)2.05485375
110Glomerulopathy (HP:0100820)2.05417748
111Chromsome breakage (HP:0040012)2.04997433
112Recurrent sinusitis (HP:0011108)2.03421440
113Microcytic anemia (HP:0001935)2.02575417
114Abnormality of the pleura (HP:0002103)2.02454546
115Nonimmune hydrops fetalis (HP:0001790)2.02119453
116Facial diplegia (HP:0001349)2.00592864
117Recurrent lower respiratory tract infections (HP:0002783)1.99082950
118Skin ulcer (HP:0200042)1.97953623
119Amyloidosis (HP:0011034)1.95227297
120Abnormality of the peritoneum (HP:0002585)1.95103411
121Polycythemia (HP:0001901)1.94513555
122Joint swelling (HP:0001386)1.92471728

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K13.79255796
2TIE13.31193235
3TXK3.14734799
4MAP3K142.79916749
5TGFBR22.76019889
6IRAK42.71146755
7TEC2.62839326
8KIT2.62731218
9KDR2.20119358
10BTK2.15450150
11BLK2.14970492
12PRPF4B2.12365946
13JAK31.96799825
14TGFBR11.94490602
15MAP3K131.91949633
16IKBKE1.90214090
17ZAP701.82929389
18CLK11.77380027
19IRAK31.70642008
20STK101.68179463
21TBK11.61274857
22TYK21.57572647
23SYK1.56762894
24ITK1.55557672
25CSF1R1.50431643
26PIM11.47519225
27PIM21.43102110
28IKBKB1.42144873
29NLK1.41834395
30CDK81.41664770
31NME21.39375716
32MAP2K31.29272788
33MKNK11.28793504
34PIK3CG1.26376530
35MATK1.26180450
36FLT31.22015893
37FGR1.21192246
38TAOK31.20891982
39FES1.19001788
40LCK1.18886307
41LYN1.17755687
42MKNK21.14802232
43MAP3K111.12268760
44MAP3K31.11950657
45NEK91.10911458
46HCK1.09626915
47CSK1.04462076
48SIK31.03688151
49MAP3K121.01635107
50ACVR1B1.00133894
51JAK10.96971593
52CAMKK20.96775158
53VRK10.95658498
54FGFR30.95160356
55TESK20.93044719
56CHUK0.92979371
57MAP3K10.89629220
58STK40.88366245
59TSSK60.86240625
60TRPM70.83391310
61CAMKK10.82734779
62GRK60.80911424
63PDK10.79350031
64LRRK20.79045133
65PTK2B0.78227526
66EEF2K0.78203270
67TNK20.77478050
68TAOK10.77233291
69PASK0.76135755
70BRSK20.76058965
71STK160.75915939
72ZAK0.73200486
73EIF2AK20.72803607
74WEE10.72249773
75GRK70.68815440
76IRAK10.68284138
77RPS6KA40.68099281
78MAPK120.67229275
79HIPK20.66932005
80CDK60.65868727
81PAK40.65828381
82RIPK40.63961752
83MAPK70.63657651
84CDK40.62331209
85NUAK10.61914458
86BMPR20.60401626
87MST40.60356245
88BMPR1B0.59945810
89MARK30.59732263
90EIF2AK30.58552226
91MYLK0.58358971
92MARK20.58040441
93FYN0.57247880
94ATR0.57093410
95MAP3K70.56538296
96PRKD20.55806919
97MAPK40.55455669
98CDK90.54795128
99RPS6KA60.53874213
100YES10.53660752
101CCNB10.53023416
102GRK10.52668340
103PDPK10.51527449
104MAPKAPK50.51089921
105PRKG20.50524196
106TNIK0.50405424
107CDC70.50190579
108MAP2K20.49881670
109ERN10.49649112
110TAOK20.47927346
111RPS6KB20.47903054
112KSR20.47875534
113SRPK10.47354824
114EPHB10.45462952
115RPS6KL10.45136107
116RPS6KC10.45136107
117MAP3K100.43696436
118SGK30.43378126
119MAP2K60.42383201
120NEK60.42315845
121MUSK0.41747307
122SGK20.39970589
123MAP3K60.39916317
124PRKCQ0.39834074
125CDK70.38821880
126JAK20.38769360
127ADRBK20.37992620
128SIK20.37938965
129STK110.36631035
130GRK50.32073337
131MAP3K50.31471574
132PTK60.31427114
133MAPKAPK20.30980508
134RET0.30930405
135RAF10.30743646
136IRAK20.29450003
137ABL10.29347237
138CDC42BPA0.28411739
139SMG10.27800203
140PRKD10.26796336
141MAPK110.24795929
142EGFR0.24755696
143PRKCH0.24245185
144MAPK30.24048401

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053403.16934281
2DNA replication_Homo sapiens_hsa030302.71915350
3Leishmaniasis_Homo sapiens_hsa051402.39511519
4Intestinal immune network for IgA production_Homo sapiens_hsa046722.27379138
5Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.22616195
6NF-kappa B signaling pathway_Homo sapiens_hsa040642.18210534
7Hematopoietic cell lineage_Homo sapiens_hsa046402.16626235
8Measles_Homo sapiens_hsa051622.14176843
9Antigen processing and presentation_Homo sapiens_hsa046122.11330173
10B cell receptor signaling pathway_Homo sapiens_hsa046622.10219575
11Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.09814888
12Mismatch repair_Homo sapiens_hsa034301.99193046
13Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.94134207
14Ribosome_Homo sapiens_hsa030101.93240810
15Base excision repair_Homo sapiens_hsa034101.84091593
16RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.83662220
17Osteoclast differentiation_Homo sapiens_hsa043801.81134405
18Herpes simplex infection_Homo sapiens_hsa051681.68052454
19Allograft rejection_Homo sapiens_hsa053301.67310980
20Homologous recombination_Homo sapiens_hsa034401.62016083
21Toll-like receptor signaling pathway_Homo sapiens_hsa046201.61118914
22Staphylococcus aureus infection_Homo sapiens_hsa051501.60745626
23Jak-STAT signaling pathway_Homo sapiens_hsa046301.56366001
24Legionellosis_Homo sapiens_hsa051341.50979444
25Malaria_Homo sapiens_hsa051441.46739393
26Graft-versus-host disease_Homo sapiens_hsa053321.46536763
27Platelet activation_Homo sapiens_hsa046111.43845047
28Pertussis_Homo sapiens_hsa051331.36886047
29Leukocyte transendothelial migration_Homo sapiens_hsa046701.33854685
30NOD-like receptor signaling pathway_Homo sapiens_hsa046211.32051042
31Other glycan degradation_Homo sapiens_hsa005111.31232509
32Influenza A_Homo sapiens_hsa051641.29020204
33* Transcriptional misregulation in cancer_Homo sapiens_hsa052021.28929661
34Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.28133369
35Toxoplasmosis_Homo sapiens_hsa051451.26625712
36T cell receptor signaling pathway_Homo sapiens_hsa046601.22829608
37Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.21263064
38Hepatitis B_Homo sapiens_hsa051611.20867359
39Viral myocarditis_Homo sapiens_hsa054161.20672010
40Nucleotide excision repair_Homo sapiens_hsa034201.19076550
41Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.18091258
42Non-homologous end-joining_Homo sapiens_hsa034501.17888626
43Shigellosis_Homo sapiens_hsa051311.17304791
44Asthma_Homo sapiens_hsa053101.15864712
45Fanconi anemia pathway_Homo sapiens_hsa034601.14318795
46Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.13030916
47Spliceosome_Homo sapiens_hsa030401.11665941
48Apoptosis_Homo sapiens_hsa042101.11070825
49Tuberculosis_Homo sapiens_hsa051521.07772371
50Chemokine signaling pathway_Homo sapiens_hsa040621.07484468
51Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.06603008
52Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.05160915
53Acute myeloid leukemia_Homo sapiens_hsa052211.04894780
54Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.00405645
55Glycosaminoglycan degradation_Homo sapiens_hsa005311.00368388
56Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.00271923
57Cell cycle_Homo sapiens_hsa041100.99612010
58TNF signaling pathway_Homo sapiens_hsa046680.96985773
59Autoimmune thyroid disease_Homo sapiens_hsa053200.96491305
60Pyrimidine metabolism_Homo sapiens_hsa002400.96295732
61Salmonella infection_Homo sapiens_hsa051320.93848046
62RNA degradation_Homo sapiens_hsa030180.89438892
63Epstein-Barr virus infection_Homo sapiens_hsa051690.84922476
64VEGF signaling pathway_Homo sapiens_hsa043700.83951907
65SNARE interactions in vesicular transport_Homo sapiens_hsa041300.81570292
66p53 signaling pathway_Homo sapiens_hsa041150.81383037
67Viral carcinogenesis_Homo sapiens_hsa052030.79527896
68RNA polymerase_Homo sapiens_hsa030200.79328368
69HTLV-I infection_Homo sapiens_hsa051660.78402930
70AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.77203151
71Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.76168721
72Chronic myeloid leukemia_Homo sapiens_hsa052200.75311152
73Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.72584980
74Prolactin signaling pathway_Homo sapiens_hsa049170.71251838
75Phospholipase D signaling pathway_Homo sapiens_hsa040720.68370907
76Pancreatic cancer_Homo sapiens_hsa052120.67983338
77Hepatitis C_Homo sapiens_hsa051600.66891374
78Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.66349531
79Phosphatidylinositol signaling system_Homo sapiens_hsa040700.66220594
80Small cell lung cancer_Homo sapiens_hsa052220.65981883
81N-Glycan biosynthesis_Homo sapiens_hsa005100.65540489
82Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.65533058
83African trypanosomiasis_Homo sapiens_hsa051430.65333727
84Systemic lupus erythematosus_Homo sapiens_hsa053220.65229523
85Endocytosis_Homo sapiens_hsa041440.64211874
86Sphingolipid signaling pathway_Homo sapiens_hsa040710.63555533
87Renal cell carcinoma_Homo sapiens_hsa052110.61603676
88Rheumatoid arthritis_Homo sapiens_hsa053230.61543963
89Dorso-ventral axis formation_Homo sapiens_hsa043200.61005433
90Notch signaling pathway_Homo sapiens_hsa043300.60136521
91Protein export_Homo sapiens_hsa030600.58926786
92Basal transcription factors_Homo sapiens_hsa030220.58893801
93Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.58887514
94Amoebiasis_Homo sapiens_hsa051460.54619303
95Inositol phosphate metabolism_Homo sapiens_hsa005620.53297869
96Lysosome_Homo sapiens_hsa041420.52531508
97Choline metabolism in cancer_Homo sapiens_hsa052310.52459851
98Caffeine metabolism_Homo sapiens_hsa002320.50822567
99HIF-1 signaling pathway_Homo sapiens_hsa040660.50048078
100Thyroid cancer_Homo sapiens_hsa052160.49871203
101Purine metabolism_Homo sapiens_hsa002300.49437926
102Adipocytokine signaling pathway_Homo sapiens_hsa049200.49371959
103GnRH signaling pathway_Homo sapiens_hsa049120.47548883
104Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.47339577
105MAPK signaling pathway_Homo sapiens_hsa040100.46914477
106Glycerophospholipid metabolism_Homo sapiens_hsa005640.46798345
107Rap1 signaling pathway_Homo sapiens_hsa040150.44799594
108Carbohydrate digestion and absorption_Homo sapiens_hsa049730.44577493
109Phagosome_Homo sapiens_hsa041450.44533450
110Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.43843054
111Regulation of autophagy_Homo sapiens_hsa041400.43175286
112Regulation of actin cytoskeleton_Homo sapiens_hsa048100.42886925
113Insulin resistance_Homo sapiens_hsa049310.42621527
114Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.42205200
115mTOR signaling pathway_Homo sapiens_hsa041500.40752937
116Colorectal cancer_Homo sapiens_hsa052100.39814397
117Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.38419288
118Long-term potentiation_Homo sapiens_hsa047200.38176545
119Neurotrophin signaling pathway_Homo sapiens_hsa047220.37170528
120Ras signaling pathway_Homo sapiens_hsa040140.37104216
121Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.36276650
122Non-small cell lung cancer_Homo sapiens_hsa052230.35341207
123RNA transport_Homo sapiens_hsa030130.34911535
124Arachidonic acid metabolism_Homo sapiens_hsa005900.34648889
125Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.32763450
126Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.32010515
127Pathways in cancer_Homo sapiens_hsa052000.31650046
128FoxO signaling pathway_Homo sapiens_hsa040680.31585481
129Type I diabetes mellitus_Homo sapiens_hsa049400.30428435

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