FLNA

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cell adhesion mediated by integrin (GO:0033627)4.43032052
2endodermal cell differentiation (GO:0035987)4.08900466
3collagen fibril organization (GO:0030199)3.84436583
4apoptotic cell clearance (GO:0043277)3.82505024
5chondrocyte proliferation (GO:0035988)3.80065737
6protein heterotrimerization (GO:0070208)3.61364985
7negative regulation of fatty acid transport (GO:2000192)3.58253423
8wound healing, spreading of epidermal cells (GO:0035313)3.43749087
9skin morphogenesis (GO:0043589)3.40345492
10barbed-end actin filament capping (GO:0051016)3.40308608
11cell-substrate junction assembly (GO:0007044)3.31098477
12neuron projection extension involved in neuron projection guidance (GO:1902284)3.28431861
13axon extension involved in axon guidance (GO:0048846)3.28431861
14positive regulation of endothelial cell apoptotic process (GO:2000353)3.25884644
15regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.20770232
16stress fiber assembly (GO:0043149)3.10937654
17hippo signaling (GO:0035329)3.10610545
18adherens junction assembly (GO:0034333)3.09063987
19epithelial cell-cell adhesion (GO:0090136)3.06638463
20vascular endothelial growth factor signaling pathway (GO:0038084)3.04548283
21embryonic process involved in female pregnancy (GO:0060136)3.04351024
22nuclear pore complex assembly (GO:0051292)3.03089347
23substrate-dependent cell migration (GO:0006929)3.00707947
24regulation of early endosome to late endosome transport (GO:2000641)2.97949945
25positive regulation of receptor recycling (GO:0001921)2.97941127
26cellular response to interferon-alpha (GO:0035457)2.96498510
27plasma membrane repair (GO:0001778)2.96338636
28positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.93456046
29mannose metabolic process (GO:0006013)2.92402939
30wound healing, spreading of cells (GO:0044319)2.91932479
31germ cell migration (GO:0008354)2.91562582
32pinocytosis (GO:0006907)2.91350257
33sequestering of extracellular ligand from receptor (GO:0035581)2.91204962
34cortical actin cytoskeleton organization (GO:0030866)2.90995485
35positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.90183271
36regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.89923533
37mesodermal cell differentiation (GO:0048333)2.87070756
38substrate adhesion-dependent cell spreading (GO:0034446)2.85426035
39regulation of integrin activation (GO:0033623)2.81484415
40basement membrane organization (GO:0071711)2.81073972
41regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.78392208
42collagen metabolic process (GO:0032963)2.78110942
43insulin-like growth factor receptor signaling pathway (GO:0048009)2.77345215
44cytoskeletal anchoring at plasma membrane (GO:0007016)2.76836341
45response to laminar fluid shear stress (GO:0034616)2.74458983
46vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.72345855
47response to fluid shear stress (GO:0034405)2.70603698
48cell migration involved in sprouting angiogenesis (GO:0002042)2.70287199
49regulation of SMAD protein import into nucleus (GO:0060390)2.69489634
50membrane protein ectodomain proteolysis (GO:0006509)2.69381948
51collagen catabolic process (GO:0030574)2.68597766
52negative regulation of erythrocyte differentiation (GO:0045647)2.68312006
53positive regulation of blood vessel endothelial cell migration (GO:0043536)2.66101902
54regulation of hippo signaling (GO:0035330)2.65194621
55positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.64650108
56hemidesmosome assembly (GO:0031581)2.64060327
57protein localization to endosome (GO:0036010)2.63410002
58nuclear pore organization (GO:0006999)2.63064382
59integrin-mediated signaling pathway (GO:0007229)2.63050645
60renal filtration (GO:0097205)2.62242836
61positive regulation of SMAD protein import into nucleus (GO:0060391)2.61927808
62multicellular organismal macromolecule metabolic process (GO:0044259)2.59435878
63regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.58884206
64heterotypic cell-cell adhesion (GO:0034113)2.58292929
65activation of Rac GTPase activity (GO:0032863)2.57802438
66polarized epithelial cell differentiation (GO:0030859)2.57433196
67regulation of extracellular matrix disassembly (GO:0010715)2.54521052
68focal adhesion assembly (GO:0048041)2.54398534
69cell-substrate adherens junction assembly (GO:0007045)2.54398534
70negative regulation of anoikis (GO:2000811)2.52924261
71extracellular matrix disassembly (GO:0022617)2.52139005
72negative regulation of chondrocyte differentiation (GO:0032331)2.51051577
73blood vessel endothelial cell migration (GO:0043534)2.50786851
74membrane raft organization (GO:0031579)2.50076890
75hyaluronan catabolic process (GO:0030214)2.49346180
76protein retention in ER lumen (GO:0006621)2.48123168
77positive regulation of epithelial to mesenchymal transition (GO:0010718)2.47846770
78actin filament bundle assembly (GO:0051017)2.47727088
79actin filament bundle organization (GO:0061572)2.47727088
80extracellular matrix assembly (GO:0085029)2.46766128
81maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.46765802
82positive regulation of natural killer cell differentiation (GO:0032825)2.45579090
83glucocorticoid receptor signaling pathway (GO:0042921)2.44974116
84heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.44917423
85regulation of tight junction assembly (GO:2000810)2.44644696
86cortical cytoskeleton organization (GO:0030865)2.44424568
87bone trabecula formation (GO:0060346)2.43803722
88regulation of mitotic spindle organization (GO:0060236)2.43409373
89semaphorin-plexin signaling pathway (GO:0071526)2.42965368
90cellular response to vitamin (GO:0071295)2.42875292
91multicellular organismal catabolic process (GO:0044243)2.42450188
92retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.41309857
93* platelet aggregation (GO:0070527)2.40741588
94regulation of glucose import in response to insulin stimulus (GO:2001273)2.40284498
95cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.40032631
96multicellular organismal metabolic process (GO:0044236)2.39790829
97chondroitin sulfate biosynthetic process (GO:0030206)2.39567759
98fibroblast migration (GO:0010761)2.38754244
99negative regulation of smooth muscle cell migration (GO:0014912)2.38165091
100heterochromatin organization (GO:0070828)2.37834850
101endocardial cushion development (GO:0003197)2.37642351
102positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241)2.36397919
103positive regulation of extracellular matrix organization (GO:1903055)2.36310200
104positive regulation of Cdc42 GTPase activity (GO:0043089)2.36137609
105antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.34600125
106NLS-bearing protein import into nucleus (GO:0006607)2.34046904
107cellular response to vitamin D (GO:0071305)2.32628074
108negative regulation of cell size (GO:0045792)2.32592436
109positive regulation of histone deacetylation (GO:0031065)2.31660468
110morphogenesis of an endothelium (GO:0003159)2.31612719
111endothelial tube morphogenesis (GO:0061154)2.31612719
112mammary gland epithelial cell proliferation (GO:0033598)2.30541553
113pentose-phosphate shunt (GO:0006098)2.30217977
114regulation of anoikis (GO:2000209)2.29786730
115endocytic recycling (GO:0032456)2.29706133
116retina vasculature morphogenesis in camera-type eye (GO:0061299)2.29704644
117glial cell migration (GO:0008347)2.29274880
118pore complex assembly (GO:0046931)2.28154349
119regulation of translational fidelity (GO:0006450)2.27147625
120glomerular visceral epithelial cell development (GO:0072015)2.26864050
121regulation of protein heterodimerization activity (GO:0043497)2.25657327
122positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.25268326
123establishment of apical/basal cell polarity (GO:0035089)2.24533605
124hypotonic response (GO:0006971)2.24403765
125planar cell polarity pathway involved in neural tube closure (GO:0090179)2.24343694
126regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.24191142
127modulation by symbiont of host cellular process (GO:0044068)2.24153104
128positive regulation of osteoblast proliferation (GO:0033690)2.24146366
129apoptotic process involved in morphogenesis (GO:0060561)2.24004409
130positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.23728067
131corticosteroid receptor signaling pathway (GO:0031958)2.23626364
132actin filament depolymerization (GO:0030042)2.23536742
133endothelial cell morphogenesis (GO:0001886)2.23301197
134atrioventricular valve morphogenesis (GO:0003181)2.22040342
135mesenchymal-epithelial cell signaling (GO:0060638)2.21463904
136fibril organization (GO:0097435)2.21299722
137regulation of transforming growth factor beta1 production (GO:0032908)2.20619104
138dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.20210747
139COPI coating of Golgi vesicle (GO:0048205)2.18901764
140Golgi transport vesicle coating (GO:0048200)2.18901764
141antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.17399963

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EGR1_19374776_ChIP-ChIP_THP-1_Human4.44372698
2NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse4.38672373
3E2F7_22180533_ChIP-Seq_HELA_Human4.28577306
4TP63_17297297_ChIP-ChIP_HaCaT_Human3.96186835
5FOXM1_23109430_ChIP-Seq_U2OS_Human3.49270326
6RARG_19884340_ChIP-ChIP_MEFs_Mouse3.19673783
7FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.80184337
8TRIM28_21343339_ChIP-Seq_HEK293_Human2.68308358
9CLOCK_20551151_ChIP-Seq_293T_Human2.64557589
10RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.45125197
11MYC_22102868_ChIP-Seq_BL_Human2.35514828
12ELK3_25401928_ChIP-Seq_HUVEC_Human2.32752298
13STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.16051524
14TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.10822499
15VDR_21846776_ChIP-Seq_THP-1_Human1.96516995
16THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.95131567
17HIF1A_21447827_ChIP-Seq_MCF-7_Human1.93079655
18SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.91580002
19KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.89607570
20SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.85602604
21SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.85602604
22* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.84007474
23STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.83623950
24TCF7_22412390_ChIP-Seq_EML_Mouse1.80711487
25* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.80158113
26CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.78668804
27FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.75233454
28BRD4_25478319_ChIP-Seq_HGPS_Human1.74709503
29* MYB_21317192_ChIP-Seq_ERMYB_Mouse1.74277710
30* KDM2B_26808549_Chip-Seq_DND41_Human1.73174347
31KDM2B_26808549_Chip-Seq_K562_Human1.70838571
32P300_27058665_Chip-Seq_ZR-75-30cells_Human1.69858350
33BRD4_27068464_Chip-Seq_AML-cells_Mouse1.68632005
34TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.66908258
35* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.64396793
36STAT6_21828071_ChIP-Seq_BEAS2B_Human1.64350882
37* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.62906279
38SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.62083074
39WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.57153173
40ATF3_27146783_Chip-Seq_COLON_Human1.56363499
41NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.54821364
42* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.53684429
43ZNF263_19887448_ChIP-Seq_K562_Human1.52703600
44* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.51517496
45SMAD_19615063_ChIP-ChIP_OVARY_Human1.50714815
46MAF_26560356_Chip-Seq_TH1_Human1.49527529
47FOXO3_23340844_ChIP-Seq_DLD1_Human1.47637063
48PPAR_26484153_Chip-Seq_NCI-H1993_Human1.44851420
49ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.43596096
50* UTX_26944678_Chip-Seq_JUKART_Human1.43006199
51* MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.42931316
52KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.42881067
53AR_21909140_ChIP-Seq_LNCAP_Human1.41632019
54WT1_19549856_ChIP-ChIP_CCG9911_Human1.40637125
55* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.39961231
56STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.39715510
57UBF1/2_26484160_Chip-Seq_HMECs_Human1.38127280
58RACK7_27058665_Chip-Seq_MCF-7_Human1.37308053
59TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.35077665
60VDR_24763502_ChIP-Seq_THP-1_Human1.34539001
61IRF8_22096565_ChIP-ChIP_GC-B_Human1.34388498
62TP53_22127205_ChIP-Seq_IMR90_Human1.34382687
63* CJUN_26792858_Chip-Seq_BT549_Human1.33493864
64CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.31389381
65DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.30402573
66ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.30389643
67NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.30340701
68KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.28173969
69TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.25764193
70IRF8_27001747_Chip-Seq_BMDM_Mouse1.25582732
71* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.24986202
72ESR1_15608294_ChIP-ChIP_MCF-7_Human1.24947161
73* KDM2B_26808549_Chip-Seq_JURKAT_Human1.24595860
74ESR2_21235772_ChIP-Seq_MCF-7_Human1.24020220
75ZFP281_27345836_Chip-Seq_ESCs_Mouse1.23306575
76IRF8_21731497_ChIP-ChIP_J774_Mouse1.21797503
77ESR1_21235772_ChIP-Seq_MCF-7_Human1.21191108
78PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.20318597
79ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.19535300
80MYB_26560356_Chip-Seq_TH2_Human1.19216973
81* NCOR1_26117541_ChIP-Seq_K562_Human1.17865930
82ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.17361463
83FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.17056498
84TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.16448813
85EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.15911951
86VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.15144370
87SMC1_22415368_ChIP-Seq_MEFs_Mouse1.15099534
88ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.14732182
89TBX20_22080862_ChIP-Seq_HEART_Mouse1.14478060
90TBX20_22328084_ChIP-Seq_HEART_Mouse1.14478060
91JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.13076548
92HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.13039811
93SPI1_23127762_ChIP-Seq_K562_Human1.12619201
94SOX9_24532713_ChIP-Seq_HFSC_Mouse1.12529330
95ZFP281_18757296_ChIP-ChIP_E14_Mouse1.08346470
96MYB_26560356_Chip-Seq_TH1_Human1.08295885
97SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.08096592
98NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.07737100
99CTCF_27219007_Chip-Seq_ERYTHROID_Human1.06963986
100NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.06600856
101Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.05997065
102KLF4_18555785_ChIP-Seq_MESCs_Mouse1.04676044
103UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.04617994
104* RUNX1_22412390_ChIP-Seq_EML_Mouse1.04599331
105LXR_22292898_ChIP-Seq_THP-1_Human1.02678737
106ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.02352392
107TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.02020915
108FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.02012947
109E2F4_17652178_ChIP-ChIP_JURKAT_Human1.00171256
110TP53_16413492_ChIP-PET_HCT116_Human0.99244040
111FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.98945764
112* TP53_23651856_ChIP-Seq_MEFs_Mouse0.98921619
113* RUNX1_27514584_Chip-Seq_MCF-7_Human0.98724553
114TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.98668853
115TFEB_21752829_ChIP-Seq_HELA_Human0.98278384
116GATA2_21666600_ChIP-Seq_HMVEC_Human0.97492446
117CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.97174993
118FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.96966966
119POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.96362307
120TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.95897467
121KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.94391984
122E2F1_21310950_ChIP-Seq_MCF-7_Human0.94005297
123NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.93144917

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen5.39884156
2MP0003705_abnormal_hypodermis_morpholog4.11607064
3MP0010352_gastrointestinal_tract_polyps3.26266165
4MP0005275_abnormal_skin_tensile3.17644337
5MP0003566_abnormal_cell_adhesion2.91301517
6MP0003279_aneurysm2.81105345
7MP0005623_abnormal_meninges_morphology2.43782108
8MP0003091_abnormal_cell_migration2.29207772
9MP0003300_gastrointestinal_ulcer2.27923158
10MP0005503_abnormal_tendon_morphology2.22336178
11MP0004272_abnormal_basement_membrane2.14902539
12MP0006054_spinal_hemorrhage2.14760038
13MP0005076_abnormal_cell_differentiation2.13350812
14MP0005023_abnormal_wound_healing2.13056676
15MP0000569_abnormal_digit_pigmentation2.03004817
16MP0000733_abnormal_muscle_development1.94385095
17* MP0001958_emphysema1.80337887
18MP0009278_abnormal_bone_marrow1.77811224
19MP0003303_peritoneal_inflammation1.68095043
20MP0005451_abnormal_body_composition1.66519495
21MP0005257_abnormal_intraocular_pressure1.66098671
22MP0004858_abnormal_nervous_system1.56694969
23MP0008260_abnormal_autophagy1.52132005
24MP0000767_abnormal_smooth_muscle1.51916919
25MP0002877_abnormal_melanocyte_morpholog1.51313119
26MP0002060_abnormal_skin_morphology1.51170993
27MP0003950_abnormal_plasma_membrane1.50729258
28MP0005409_darkened_coat_color1.48894666
29MP0009053_abnormal_anal_canal1.45267366
30MP0000516_abnormal_urinary_system1.43604665
31MP0005367_renal/urinary_system_phenotyp1.43604665
32MP0003191_abnormal_cellular_cholesterol1.42253186
33MP0004808_abnormal_hematopoietic_stem1.40942127
34MP0000537_abnormal_urethra_morphology1.40128033
35MP0010307_abnormal_tumor_latency1.36743479
36MP0010030_abnormal_orbit_morphology1.36712449
37MP0002166_altered_tumor_susceptibility1.33154940
38MP0009384_cardiac_valve_regurgitation1.31815516
39MP0010234_abnormal_vibrissa_follicle1.31452410
40MP0003045_fibrosis1.28497543
41MP0003828_pulmonary_edema1.26488928
42MP0000751_myopathy1.26449683
43MP0004233_abnormal_muscle_weight1.25813398
44MP0000858_altered_metastatic_potential1.24064040
45MP0001243_abnormal_dermal_layer1.22094264
46MP0001542_abnormal_bone_strength1.20738769
47MP0005508_abnormal_skeleton_morphology1.20498345
48MP0003448_altered_tumor_morphology1.18219958
49MP0000534_abnormal_ureter_morphology1.16839468
50MP0009840_abnormal_foam_cell1.15253460
51MP0000428_abnormal_craniofacial_morphol1.14555220
52MP0003172_abnormal_lysosome_physiology1.12308557
53MP0004947_skin_inflammation1.06845155
54MP0003115_abnormal_respiratory_system1.04973670
55MP0001915_intracranial_hemorrhage1.04730203
56MP0002396_abnormal_hematopoietic_system1.03764585
57MP0002254_reproductive_system_inflammat1.02882797
58MP0001299_abnormal_eye_distance/1.02607603
59MP0001849_ear_inflammation1.01892506
60MP0002933_joint_inflammation1.01532181
61MP0003436_decreased_susceptibility_to1.00933629
62MP0002006_tumorigenesis1.00734444
63MP0004197_abnormal_fetal_growth/weight/0.99389748
64MP0002896_abnormal_bone_mineralization0.99075276
65* MP0002925_abnormal_cardiovascular_devel0.99022347
66MP0001533_abnormal_skeleton_physiology0.97951850
67MP0005390_skeleton_phenotype0.95819398
68MP0003941_abnormal_skin_development0.95554256
69MP0000685_abnormal_immune_system0.95163829
70MP0005595_abnormal_vascular_smooth0.94847771
71MP0002282_abnormal_trachea_morphology0.94753996
72MP0001348_abnormal_lacrimal_gland0.94711979
73MP0004185_abnormal_adipocyte_glucose0.94145708
74MP0000750_abnormal_muscle_regeneration0.92752843
75MP0003453_abnormal_keratinocyte_physiol0.91573811
76* MP0001614_abnormal_blood_vessel0.91508097
77MP0004510_myositis0.90455939
78* MP0003385_abnormal_body_wall0.89546552
79MP0002796_impaired_skin_barrier0.88021312
80MP0005164_abnormal_response_to0.87437431
81MP0002086_abnormal_extraembryonic_tissu0.85967117
82MP0002998_abnormal_bone_remodeling0.85713987
83MP0002168_other_aberrant_phenotype0.85588153
84MP0000350_abnormal_cell_proliferation0.85441105
85* MP0002128_abnormal_blood_circulation0.83774202
86MP0000462_abnormal_digestive_system0.82414937
87MP0005397_hematopoietic_system_phenotyp0.82161038
88MP0001545_abnormal_hematopoietic_system0.82161038
89MP0002113_abnormal_skeleton_development0.82091345
90MP0000762_abnormal_tongue_morphology0.80033451
91MP0010630_abnormal_cardiac_muscle0.79925404
92MP0005501_abnormal_skin_physiology0.79678089
93MP0000759_abnormal_skeletal_muscle0.78517105
94MP0001730_embryonic_growth_arrest0.78292708
95MP0002088_abnormal_embryonic_growth/wei0.78026215
96MP0003984_embryonic_growth_retardation0.77276418
97MP0002115_abnormal_skeleton_extremities0.76930019
98MP0008007_abnormal_cellular_replicative0.76772388
99MP0002932_abnormal_joint_morphology0.76600206
100MP0005375_adipose_tissue_phenotype0.76280847
101MP0000465_gastrointestinal_hemorrhage0.76237988
102MP0003942_abnormal_urinary_system0.75974421
103MP0003763_abnormal_thymus_physiology0.75847967
104MP0006138_congestive_heart_failure0.75771507
105MP0001216_abnormal_epidermal_layer0.75491014
106MP0001851_eye_inflammation0.75423985
107MP0002089_abnormal_postnatal_growth/wei0.75140981
108MP0000432_abnormal_head_morphology0.74881502
109MP0002295_abnormal_pulmonary_circulatio0.74476555
110MP0002084_abnormal_developmental_patter0.73950606
111MP0005621_abnormal_cell_physiology0.73520636
112MP0002697_abnormal_eye_size0.72653402
113MP0000013_abnormal_adipose_tissue0.72355601
114* MP0003935_abnormal_craniofacial_develop0.72243514
115MP0001672_abnormal_embryogenesis/_devel0.71866594
116MP0005380_embryogenesis_phenotype0.71866594
117MP0003795_abnormal_bone_structure0.71468383
118MP0000003_abnormal_adipose_tissue0.71455279
119MP0003283_abnormal_digestive_organ0.70944773
120MP0010368_abnormal_lymphatic_system0.69581263
121MP0002419_abnormal_innate_immunity0.68532118
122MP0001879_abnormal_lymphatic_vessel0.67965413
123MP0002085_abnormal_embryonic_tissue0.67441232
124MP0009250_abnormal_appendicular_skeleto0.67161606
125MP0004087_abnormal_muscle_fiber0.67071208
126MP0000467_abnormal_esophagus_morphology0.66398280
127* MP0001175_abnormal_lung_morphology0.65109060
128MP0005058_abnormal_lysosome_morphology0.64943625
129MP0000163_abnormal_cartilage_morphology0.64349028
130MP0003329_amyloid_beta_deposits0.64279929
131MP0005464_abnormal_platelet_physiology0.64076607
132MP0005384_cellular_phenotype0.63651513
133MP0009780_abnormal_chondrocyte_physiolo0.61967571

Predicted human phenotypes

RankGene SetZ-score
1Premature rupture of membranes (HP:0001788)5.70902831
2Protrusio acetabuli (HP:0003179)5.66119355
3Aortic aneurysm (HP:0004942)5.23115193
4Aortic dissection (HP:0002647)5.12806963
5Cerebral aneurysm (HP:0004944)4.87716269
6Shallow orbits (HP:0000586)4.53939436
7Cervical subluxation (HP:0003308)3.80157235
8Peritonitis (HP:0002586)3.58169829
9Atrophic scars (HP:0001075)3.49955965
10* Dilatation of the ascending aorta (HP:0005111)3.35739417
11Bladder diverticulum (HP:0000015)3.13410436
12Broad metatarsal (HP:0001783)3.12160424
13* Ankle contracture (HP:0006466)3.11552386
14Increased connective tissue (HP:0009025)3.04254044
15Genu recurvatum (HP:0002816)2.97629871
16* Mitral valve prolapse (HP:0001634)2.96057924
17Soft skin (HP:0000977)2.95965949
18Aneurysm (HP:0002617)2.93382368
19Fragile skin (HP:0001030)2.88480735
20Bowel diverticulosis (HP:0005222)2.63642039
21Syringomyelia (HP:0003396)2.61526596
22Spinal cord lesions (HP:0100561)2.61526596
23Blue sclerae (HP:0000592)2.55487501
24Thin bony cortex (HP:0002753)2.52630287
25Short nail (HP:0001799)2.46453389
26Type 1 muscle fiber predominance (HP:0003803)2.41890996
27Vascular tortuosity (HP:0004948)2.39215735
28Spinal rigidity (HP:0003306)2.38982740
29Distal upper limb amyotrophy (HP:0007149)2.37297133
30Upper limb amyotrophy (HP:0009129)2.37297133
31Abnormality of dentin (HP:0010299)2.32840789
32Natal tooth (HP:0000695)2.31871529
33Distal lower limb muscle weakness (HP:0009053)2.31199453
34Vertebral compression fractures (HP:0002953)2.30974766
35* Wormian bones (HP:0002645)2.29860920
36Abnormality of the peritoneum (HP:0002585)2.27883311
37Achilles tendon contracture (HP:0001771)2.24602545
38Arterial tortuosity (HP:0005116)2.23291853
39Deviation of the hallux (HP:0010051)2.22051285
40Subacute progressive viral hepatitis (HP:0006572)2.19663257
41Hematochezia (HP:0002573)2.16573235
42* Osteolytic defects of the hand bones (HP:0009699)2.16366121
43* Osteolytic defects of the phalanges of the hand (HP:0009771)2.16366121
44Hallux valgus (HP:0001822)2.16033519
45Spondylolisthesis (HP:0003302)2.14966937
46Distal lower limb amyotrophy (HP:0008944)2.12980526
47Broad ribs (HP:0000885)2.11156695
48Neonatal short-limb short stature (HP:0008921)2.10453723
49Abnormality of the acetabulum (HP:0003170)2.08921764
50Joint laxity (HP:0001388)2.06199433
51Biconcave vertebral bodies (HP:0004586)2.02811403
52Long palpebral fissure (HP:0000637)2.00703127
53Hyperacusis (HP:0010780)2.00655223
54Difficulty climbing stairs (HP:0003551)2.00590104
55Ankyloglossia (HP:0010296)1.99215320
56Follicular hyperkeratosis (HP:0007502)1.98271497
57Hand muscle atrophy (HP:0009130)1.96570158
58* Broad face (HP:0000283)1.96568094
59Mitral stenosis (HP:0001718)1.95962504
60Buphthalmos (HP:0000557)1.95227286
61Abnormality of the Achilles tendon (HP:0005109)1.91221189
62Slender build (HP:0001533)1.89258374
63Striae distensae (HP:0001065)1.88254326
64Rectal prolapse (HP:0002035)1.87771841
65* Camptodactyly of toe (HP:0001836)1.87604087
66* Scapular winging (HP:0003691)1.87298642
67Interstitial pulmonary disease (HP:0006530)1.87118686
68Hyperextensible skin (HP:0000974)1.86322846
69Asymmetry of the thorax (HP:0001555)1.85927459
70Disproportionate tall stature (HP:0001519)1.85309096
71Ectopia lentis (HP:0001083)1.85011554
72Overgrowth (HP:0001548)1.83368315
73Mildly elevated creatine phosphokinase (HP:0008180)1.82421450
74* Radial bowing (HP:0002986)1.82123274
75* Elbow flexion contracture (HP:0002987)1.80750939
76Advanced eruption of teeth (HP:0006288)1.78121275
77Obstructive sleep apnea (HP:0002870)1.77481929
78Generalized amyotrophy (HP:0003700)1.77112939
79* Increased density of long bones (HP:0006392)1.76982308
80Increased variability in muscle fiber diameter (HP:0003557)1.76638674
81Joint stiffness (HP:0001387)1.75211916
82Spinal cord compression (HP:0002176)1.74909824
83Vertebral arch anomaly (HP:0008438)1.74368031
84Abnormality of the distal phalanges of the toes (HP:0010182)1.74211803
85Insomnia (HP:0100785)1.73393127
86Aortic valve stenosis (HP:0001650)1.73307970
87Long eyelashes (HP:0000527)1.71870439
88* Ulnar bowing (HP:0003031)1.71728493
89High pitched voice (HP:0001620)1.71471021
90* Bicuspid aortic valve (HP:0001647)1.69599039
91Arnold-Chiari malformation (HP:0002308)1.69358580
92* Abnormality of the calcaneus (HP:0008364)1.69102326
93* Aortic regurgitation (HP:0001659)1.68896292
94Flat acetabular roof (HP:0003180)1.68819963
95* Mitral regurgitation (HP:0001653)1.68237138
96* Bowing of the arm (HP:0006488)1.67882784
97* Bowed forearm bones (HP:0003956)1.67882784
98Abnormality of skeletal muscle fiber size (HP:0012084)1.66584928
99Abnormality of skull ossification (HP:0002703)1.65444205
100Flat cornea (HP:0007720)1.65257400
101Premature skin wrinkling (HP:0100678)1.63878392
102Myocardial infarction (HP:0001658)1.63079632
103Coxa vara (HP:0002812)1.62991312
104* Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.62706988
105* Short 4th metacarpal (HP:0010044)1.62706988
106Abnormal vertebral ossification (HP:0100569)1.62656750
107Enlarged penis (HP:0000040)1.60695150
108Entropion (HP:0000621)1.60186349
109Lower limb amyotrophy (HP:0007210)1.60177908
110Renal duplication (HP:0000075)1.58853801
111Abnormal delivery (HP:0001787)1.57715526
112Lymphangioma (HP:0100764)1.57448275
113Venous abnormality (HP:0002624)1.56998719
114Inguinal hernia (HP:0000023)1.56928127
115Frequent falls (HP:0002359)1.56317331
116Cellulitis (HP:0100658)1.56229159
117Macroorchidism (HP:0000053)1.55739303
118Milia (HP:0001056)1.55362508
119Round ear (HP:0100830)1.53508266
120Severe short stature (HP:0003510)1.53139077
121* Broad long bones (HP:0005622)1.52875277
122* Flexion contracture of toe (HP:0005830)1.52361507
123* Joint contractures involving the joints of the feet (HP:0100492)1.52361507
124Thoracolumbar scoliosis (HP:0002944)1.51307268
125Hypoventilation (HP:0002791)1.51299772
126Bilateral sensorineural hearing impairment (HP:0008619)1.51246953
127Urethral obstruction (HP:0000796)1.51044783
128Abnormality of carpal bone ossification (HP:0006257)1.50829582
129Relative macrocephaly (HP:0004482)1.50227232
130Narrow palate (HP:0000189)1.50171349
131Dysostosis multiplex (HP:0000943)1.50076342
132Trismus (HP:0000211)1.49751556

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.22995464
2PKN23.33994241
3EEF2K3.07406240
4PRPF4B2.82253027
5SMG12.78120882
6IRAK32.77097615
7PDGFRA2.70962370
8DDR22.52336284
9RIPK12.29731745
10CDK122.26198750
11LATS12.16900328
12PAK22.15617367
13PTK62.11623552
14LRRK22.11196829
15MAP3K102.08865489
16STK102.05595815
17DMPK1.99356376
18TRPM71.82715960
19EPHA21.74073163
20BMX1.68643974
21SIK11.67546657
22ERN11.66889942
23MYLK1.66372491
24PAK41.63507864
25PTK21.56173635
26RPS6KA41.45252819
27SCYL21.42060648
28CAMK1D1.41130827
29TESK11.40805813
30TGFBR21.34638548
31NTRK11.33122382
32PDGFRB1.31801687
33JAK31.27457493
34MAP3K131.25186491
35STK31.24256341
36PRKD21.19040419
37NEK21.15518739
38* MTOR1.15461956
39RPS6KB21.14140381
40EPHB11.11240647
41TAOK21.10814983
42MAP3K61.08425394
43MAP2K31.04665246
44MAP3K81.03821280
45MAP4K11.03810671
46ILK1.02960401
47CDK61.00638766
48EPHB20.98971683
49TGFBR10.97689589
50JAK10.97646571
51CAMK1G0.97410390
52STK380.94653413
53FGFR10.94180689
54MET0.92500348
55LATS20.91184900
56NME20.90066178
57FGFR30.87656237
58KIT0.87652530
59TYK20.87088544
60ERBB40.86229162
61FGFR40.85330920
62KSR20.85153463
63TESK20.83086497
64MARK20.83069270
65NEK90.82724862
66ALK0.77837712
67HCK0.77577177
68LMTK20.77337329
69CSK0.76734031
70EPHA30.76012799
71FER0.73691292
72FLT30.72780449
73CDC70.72450473
74LIMK10.72202643
75* RPS6KA20.70231566
76TBK10.69996758
77ROCK10.69209489
78CSF1R0.68797998
79PRKG20.66940666
80MAP3K10.65813751
81PAK30.64147897
82ITK0.63526181
83MOS0.63246756
84CDK40.61944307
85MAP3K30.61669423
86IRAK20.61523333
87PDPK10.61477690
88INSR0.60699547
89FRK0.60663105
90PRKCH0.59438495
91PTK2B0.59107808
92RET0.58651597
93ZAP700.58501265
94ROCK20.58265482
95MST1R0.57473434
96IRAK40.55920241
97MAPKAPK30.55379164
98SIK20.54915207
99PIK3CG0.54357204
100BRD40.53326695
101MAP3K70.52993772
102CHUK0.51888612
103NUAK10.51504492
104FGFR20.51267616
105HIPK20.50930733
106MAPK110.50398224
107MAPK70.49780357
108CLK10.49477422
109ARAF0.49236622
110AURKB0.49087090
111MAPKAPK20.48131978
112MELK0.47438767
113CDC42BPA0.46820718
114EGFR0.46074193
115SRC0.45716593
116MARK30.45140138
117ICK0.45088164
118FGR0.44975978
119GSK3A0.43648546
120SGK30.43512902
121MAP3K110.43090562
122PIK3CA0.43026777
123PASK0.42861415
124STK40.41796928
125CDK80.40696245
126TYRO30.40371040
127* PAK10.40173837
128CDK90.39484110
129LCK0.39249899
130CDK70.38410503
131TAOK10.37841995
132KSR10.37346363
133GRK60.36813487
134MAP3K140.36472440

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045122.57629513
2* Focal adhesion_Homo sapiens_hsa045102.37567238
3Bacterial invasion of epithelial cells_Homo sapiens_hsa051002.27343655
4Small cell lung cancer_Homo sapiens_hsa052222.13017512
5* Proteoglycans in cancer_Homo sapiens_hsa052051.98483886
6Adherens junction_Homo sapiens_hsa045201.97689064
7Chronic myeloid leukemia_Homo sapiens_hsa052201.92848691
8Leukocyte transendothelial migration_Homo sapiens_hsa046701.89135698
9AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.81390647
10Other glycan degradation_Homo sapiens_hsa005111.81073387
11Amoebiasis_Homo sapiens_hsa051461.76344769
12MicroRNAs in cancer_Homo sapiens_hsa052061.76149800
13Viral myocarditis_Homo sapiens_hsa054161.72292309
14Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.70949716
15Leishmaniasis_Homo sapiens_hsa051401.62370574
16Shigellosis_Homo sapiens_hsa051311.61073799
17Bladder cancer_Homo sapiens_hsa052191.57079380
18Regulation of actin cytoskeleton_Homo sapiens_hsa048101.52663892
19Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.51152548
20Toxoplasmosis_Homo sapiens_hsa051451.49870025
21Pancreatic cancer_Homo sapiens_hsa052121.42971436
22Platelet activation_Homo sapiens_hsa046111.42178567
23Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.37833600
24Malaria_Homo sapiens_hsa051441.35529214
25Osteoclast differentiation_Homo sapiens_hsa043801.33218104
26Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.32062026
27Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.29257486
28Hippo signaling pathway_Homo sapiens_hsa043901.27494035
29TGF-beta signaling pathway_Homo sapiens_hsa043501.27385260
30Viral carcinogenesis_Homo sapiens_hsa052031.24736666
31Apoptosis_Homo sapiens_hsa042101.23608392
32HTLV-I infection_Homo sapiens_hsa051661.22256870
33Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.22225237
34TNF signaling pathway_Homo sapiens_hsa046681.17710534
35Dilated cardiomyopathy_Homo sapiens_hsa054141.16051569
36p53 signaling pathway_Homo sapiens_hsa041151.15090817
37Colorectal cancer_Homo sapiens_hsa052101.13167665
38Hepatitis B_Homo sapiens_hsa051611.12272111
39Antigen processing and presentation_Homo sapiens_hsa046121.09128732
40NF-kappa B signaling pathway_Homo sapiens_hsa040641.08398228
41B cell receptor signaling pathway_Homo sapiens_hsa046621.05575820
42Notch signaling pathway_Homo sapiens_hsa043301.04886295
43Prostate cancer_Homo sapiens_hsa052151.04142158
44mTOR signaling pathway_Homo sapiens_hsa041501.03144047
45Glioma_Homo sapiens_hsa052141.02747537
46PI3K-Akt signaling pathway_Homo sapiens_hsa041511.02413977
47Neurotrophin signaling pathway_Homo sapiens_hsa047221.00627423
48Prion diseases_Homo sapiens_hsa050201.00483507
49Pentose phosphate pathway_Homo sapiens_hsa000301.00187131
50Pathways in cancer_Homo sapiens_hsa052000.99700165
51Endometrial cancer_Homo sapiens_hsa052130.98999150
52ErbB signaling pathway_Homo sapiens_hsa040120.98776242
53* Salmonella infection_Homo sapiens_hsa051320.98754618
54Basal cell carcinoma_Homo sapiens_hsa052170.98455099
55Acute myeloid leukemia_Homo sapiens_hsa052210.98269072
56Measles_Homo sapiens_hsa051620.96423190
57VEGF signaling pathway_Homo sapiens_hsa043700.95402034
58Non-small cell lung cancer_Homo sapiens_hsa052230.95141869
59Central carbon metabolism in cancer_Homo sapiens_hsa052300.94812450
60Rap1 signaling pathway_Homo sapiens_hsa040150.93991875
61Tight junction_Homo sapiens_hsa045300.93155923
62Melanoma_Homo sapiens_hsa052180.92012429
63Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.90910432
64Pertussis_Homo sapiens_hsa051330.90872231
65Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.90797413
66Renal cell carcinoma_Homo sapiens_hsa052110.90444842
67Tuberculosis_Homo sapiens_hsa051520.87058472
68Protein digestion and absorption_Homo sapiens_hsa049740.86362996
69Cell cycle_Homo sapiens_hsa041100.85165413
70Toll-like receptor signaling pathway_Homo sapiens_hsa046200.84632013
71Legionellosis_Homo sapiens_hsa051340.84479269
72Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.84192324
73GnRH signaling pathway_Homo sapiens_hsa049120.83900515
74Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.80626791
75HIF-1 signaling pathway_Homo sapiens_hsa040660.79819416
76Transcriptional misregulation in cancer_Homo sapiens_hsa052020.79341836
77Galactose metabolism_Homo sapiens_hsa000520.78808039
78Glycosaminoglycan degradation_Homo sapiens_hsa005310.78531282
79Hematopoietic cell lineage_Homo sapiens_hsa046400.78274750
80Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.77820397
81Inositol phosphate metabolism_Homo sapiens_hsa005620.77764646
82Phagosome_Homo sapiens_hsa041450.76874067
83Insulin signaling pathway_Homo sapiens_hsa049100.76229659
84Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.75841256
85Longevity regulating pathway - mammal_Homo sapiens_hsa042110.75804748
86Thyroid hormone signaling pathway_Homo sapiens_hsa049190.75667984
87Phosphatidylinositol signaling system_Homo sapiens_hsa040700.75501923
88T cell receptor signaling pathway_Homo sapiens_hsa046600.74601173
89Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.73852546
90Influenza A_Homo sapiens_hsa051640.73100657
91Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.73093603
92Choline metabolism in cancer_Homo sapiens_hsa052310.72878916
93Sphingolipid signaling pathway_Homo sapiens_hsa040710.72175746
94Jak-STAT signaling pathway_Homo sapiens_hsa046300.71924809
95Insulin resistance_Homo sapiens_hsa049310.70477440
96Chemokine signaling pathway_Homo sapiens_hsa040620.69579618
97NOD-like receptor signaling pathway_Homo sapiens_hsa046210.69541190
98Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.67226673
99Herpes simplex infection_Homo sapiens_hsa051680.67179736
100Systemic lupus erythematosus_Homo sapiens_hsa053220.67076988
101FoxO signaling pathway_Homo sapiens_hsa040680.67008351
102Endocytosis_Homo sapiens_hsa041440.66651780
103Prolactin signaling pathway_Homo sapiens_hsa049170.65801367
104Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.65434337
105Gap junction_Homo sapiens_hsa045400.65353794
106Thyroid cancer_Homo sapiens_hsa052160.63447414
107Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.61788281
108Lysosome_Homo sapiens_hsa041420.61057505
109Estrogen signaling pathway_Homo sapiens_hsa049150.59747265
110Adipocytokine signaling pathway_Homo sapiens_hsa049200.59300231
111Lysine degradation_Homo sapiens_hsa003100.58809995
112Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.58624960
113RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.58616720
114Melanogenesis_Homo sapiens_hsa049160.58361008
115Hedgehog signaling pathway_Homo sapiens_hsa043400.56826208
116Epstein-Barr virus infection_Homo sapiens_hsa051690.55553827
117Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.55243073
118One carbon pool by folate_Homo sapiens_hsa006700.54712616
119Hepatitis C_Homo sapiens_hsa051600.54281851
120Phospholipase D signaling pathway_Homo sapiens_hsa040720.52190736

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