FLYWCH1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)6.42852826
2regulation of short-term neuronal synaptic plasticity (GO:0048172)6.12680231
3positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.72910717
4locomotory exploration behavior (GO:0035641)5.67736975
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.41766636
6synaptic vesicle exocytosis (GO:0016079)5.23591280
7regulation of synaptic vesicle exocytosis (GO:2000300)5.12055112
8vocalization behavior (GO:0071625)5.10767254
9glutamate secretion (GO:0014047)5.09551046
10regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.81389049
11synaptic vesicle docking involved in exocytosis (GO:0016081)4.78219151
12neuronal action potential propagation (GO:0019227)4.75337975
13neurotransmitter secretion (GO:0007269)4.71274359
14regulation of synaptic vesicle transport (GO:1902803)4.56519208
15regulation of synapse structural plasticity (GO:0051823)4.54420870
16regulation of glutamate receptor signaling pathway (GO:1900449)4.53829159
17regulation of neuronal synaptic plasticity (GO:0048168)4.42769833
18protein localization to synapse (GO:0035418)4.33918355
19sodium ion export (GO:0071436)4.33842716
20ionotropic glutamate receptor signaling pathway (GO:0035235)4.31622089
21exploration behavior (GO:0035640)4.30638719
22cellular potassium ion homeostasis (GO:0030007)4.29374096
23layer formation in cerebral cortex (GO:0021819)4.27221859
24gamma-aminobutyric acid transport (GO:0015812)4.23337553
25regulation of long-term neuronal synaptic plasticity (GO:0048169)4.21963791
26mannose metabolic process (GO:0006013)4.19742689
27neuromuscular process controlling posture (GO:0050884)4.08473469
28positive regulation of synaptic transmission, dopaminergic (GO:0032226)4.07969145
29membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.01243473
30activation of protein kinase A activity (GO:0034199)3.85764008
31synaptic transmission, glutamatergic (GO:0035249)3.85745263
32neuron cell-cell adhesion (GO:0007158)3.84412380
33neurotransmitter transport (GO:0006836)3.84097859
34proline transport (GO:0015824)3.81133895
35dendritic spine morphogenesis (GO:0060997)3.80173541
36cerebellar Purkinje cell differentiation (GO:0021702)3.77026284
37glycine transport (GO:0015816)3.76890762
38negative regulation of erythrocyte differentiation (GO:0045647)3.73740372
39long-term memory (GO:0007616)3.73079914
40neuromuscular process controlling balance (GO:0050885)3.72596326
41cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.72407890
42glutamate receptor signaling pathway (GO:0007215)3.71301668
43neuron-neuron synaptic transmission (GO:0007270)3.69208784
44positive regulation of membrane potential (GO:0045838)3.63729116
45cell communication by electrical coupling (GO:0010644)3.61797414
46membrane depolarization during action potential (GO:0086010)3.57643934
47neurotransmitter-gated ion channel clustering (GO:0072578)3.57113076
48positive regulation of synaptic transmission, GABAergic (GO:0032230)3.54616526
49prepulse inhibition (GO:0060134)3.53948485
50regulation of neurotransmitter levels (GO:0001505)3.53289147
51regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.52411914
52regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.51541410
53regulation of excitatory postsynaptic membrane potential (GO:0060079)3.48283468
54transmission of nerve impulse (GO:0019226)3.43024266
55regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.42414207
56synaptic vesicle endocytosis (GO:0048488)3.42204811
57positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.39378525
58neuronal ion channel clustering (GO:0045161)3.34652165
59regulation of synaptic plasticity (GO:0048167)3.34493888
60regulation of neurotransmitter secretion (GO:0046928)3.33647891
61regulation of postsynaptic membrane potential (GO:0060078)3.33333220
62calcium ion-dependent exocytosis (GO:0017156)3.32666218
63response to auditory stimulus (GO:0010996)3.29996668
64auditory behavior (GO:0031223)3.28970229
65mating behavior (GO:0007617)3.28478903
66positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.26715446
67vesicle transport along microtubule (GO:0047496)3.25150261
68positive regulation of CREB transcription factor activity (GO:0032793)3.23883733
69positive regulation of synapse maturation (GO:0090129)3.23784631
70membrane hyperpolarization (GO:0060081)3.22516085
71negative regulation of microtubule polymerization (GO:0031115)3.20745407
72regulation of dendritic spine morphogenesis (GO:0061001)3.20658861
73cerebellar Purkinje cell layer development (GO:0021680)3.19818485
74regulation of synaptic transmission, glutamatergic (GO:0051966)3.18362500
75potassium ion import (GO:0010107)3.17361809
76membrane depolarization (GO:0051899)3.14466980
77regulation of neurotransmitter transport (GO:0051588)3.14419085
78establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.14368173
79mitochondrion transport along microtubule (GO:0047497)3.14368173
80negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.13966044
81potassium ion homeostasis (GO:0055075)3.08749838
82regulation of synapse maturation (GO:0090128)3.08365610
83positive regulation of neurotransmitter transport (GO:0051590)3.08135622
84regulation of ARF GTPase activity (GO:0032312)3.07734644
85positive regulation of histone deacetylation (GO:0031065)3.07537544
86neuron recognition (GO:0008038)3.06731304
87dendrite morphogenesis (GO:0048813)3.06372795
88negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.05527256
89G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.05427310
90regulation of ARF protein signal transduction (GO:0032012)3.04600694
91neuromuscular process (GO:0050905)3.04083845
92regulation of vesicle fusion (GO:0031338)3.03417565
93establishment of mitochondrion localization (GO:0051654)3.02577056
94positive regulation of potassium ion transmembrane transport (GO:1901381)3.02047925
95axon cargo transport (GO:0008088)2.99336432
96negative regulation of cell size (GO:0045792)2.98729225
97cell migration in hindbrain (GO:0021535)2.96998453
98cellular sodium ion homeostasis (GO:0006883)2.94961778
99long-term synaptic potentiation (GO:0060291)2.94021782
100intraspecies interaction between organisms (GO:0051703)2.93629207
101social behavior (GO:0035176)2.93629207
102gamma-aminobutyric acid signaling pathway (GO:0007214)2.92186057
103regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.90183813
104synaptic transmission (GO:0007268)2.90183670
105regulation of voltage-gated calcium channel activity (GO:1901385)2.89980983
106positive regulation of dendritic spine development (GO:0060999)2.88683904
107regulation of synaptic transmission (GO:0050804)2.88363703
108adult walking behavior (GO:0007628)2.88350687
109L-amino acid import (GO:0043092)2.86738177
110positive regulation of Rap GTPase activity (GO:0032854)2.85548726
111axonal fasciculation (GO:0007413)2.85058565
112positive regulation of synaptic transmission (GO:0050806)2.84508001
113cerebellar granule cell differentiation (GO:0021707)2.68837181
114semaphorin-plexin signaling pathway (GO:0071526)2.66464656
115cell-cell junction maintenance (GO:0045217)2.66441174
116positive regulation of protein dephosphorylation (GO:0035307)2.62293458
117thymic T cell selection (GO:0045061)2.56498560
118postsynaptic membrane organization (GO:0001941)2.51873106
119peptidyl-tyrosine autophosphorylation (GO:0038083)2.49605414
120signal complex assembly (GO:0007172)2.48621958
121atrioventricular valve morphogenesis (GO:0003181)2.44816523
122positive thymic T cell selection (GO:0045059)2.42409481
123regulation of Rap GTPase activity (GO:0032317)2.41098813
124dopamine receptor signaling pathway (GO:0007212)2.41097323
125regulation of fatty acid beta-oxidation (GO:0031998)2.40436969
126dendritic spine organization (GO:0097061)2.38270986
127activation of MAPKKK activity (GO:0000185)2.33758957
128positive regulation of protein deacetylation (GO:0090312)2.32204256
129regulation of histone deacetylation (GO:0031063)2.31794659
130negative regulation of cAMP-mediated signaling (GO:0043951)2.30879536
131regulation of extracellular matrix disassembly (GO:0010715)2.28798817
132activation of JUN kinase activity (GO:0007257)2.26998978
133negative regulation of type 2 immune response (GO:0002829)2.26162705
134negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.22371865
135histone H3 deacetylation (GO:0070932)2.21637265
136endothelial cell chemotaxis (GO:0035767)2.21049634
137positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.18156189
138regulation of respiratory system process (GO:0044065)2.17750388
139cell junction maintenance (GO:0034331)2.15333885
140phosphatidylglycerol biosynthetic process (GO:0006655)2.13327119
141negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.12421327
142negative regulation of cell killing (GO:0031342)2.12421327
143antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.12271969
144negative regulation of Ras protein signal transduction (GO:0046580)2.11685430
145ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.11510162
146protein targeting to plasma membrane (GO:0072661)2.10326806
147histone H4 deacetylation (GO:0070933)2.09896379
148cytoskeletal anchoring at plasma membrane (GO:0007016)2.09634837
149negative regulation of synaptic transmission, GABAergic (GO:0032229)2.06700009
150protein heterotrimerization (GO:0070208)2.05682625
151response to misfolded protein (GO:0051788)2.05602965
152regulation of respiratory gaseous exchange (GO:0043576)2.04499443
153axon extension (GO:0048675)2.04030138
154peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.03934646
155positive regulation of triglyceride biosynthetic process (GO:0010867)2.03129057
156negative regulation of small GTPase mediated signal transduction (GO:0051058)2.03064165
157positive regulation of protein kinase C signaling (GO:0090037)2.02384633
158membrane tubulation (GO:0097320)2.02353845
159response to muramyl dipeptide (GO:0032495)2.01416975
160mitochondrion localization (GO:0051646)2.01331113
161regulation of protein dephosphorylation (GO:0035304)2.01046636
162activation of Rac GTPase activity (GO:0032863)2.00377660

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.60837691
2SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.98501232
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.95722587
4REST_21632747_ChIP-Seq_MESCs_Mouse2.94528396
5RARB_27405468_Chip-Seq_BRAIN_Mouse2.93093967
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.87129062
7DROSHA_22980978_ChIP-Seq_HELA_Human2.72266468
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.72007358
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.72007358
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.65048121
11SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.62505891
12* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.57550188
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.56945222
14GBX2_23144817_ChIP-Seq_PC3_Human2.53479295
15VDR_21846776_ChIP-Seq_THP-1_Human2.48593223
16REST_18959480_ChIP-ChIP_MESCs_Mouse2.48144499
17MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.44606382
18SUZ12_27294783_Chip-Seq_ESCs_Mouse2.42641207
19SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.39884110
20SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.39395570
21EZH2_27294783_Chip-Seq_ESCs_Mouse2.38394346
22SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.36097468
23EZH2_27304074_Chip-Seq_ESCs_Mouse2.36056816
24* KDM2B_26808549_Chip-Seq_DND41_Human2.35489350
25IKZF1_21737484_ChIP-ChIP_HCT116_Human2.32258724
26NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.28297436
27CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.27074212
28TP63_17297297_ChIP-ChIP_HaCaT_Human2.25689009
29RARG_19884340_ChIP-ChIP_MEFs_Mouse2.25230086
30* KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.18286216
31RNF2_27304074_Chip-Seq_ESCs_Mouse2.17800842
32EED_16625203_ChIP-ChIP_MESCs_Mouse2.07701973
33* ELK3_25401928_ChIP-Seq_HUVEC_Human2.07545496
34* P68_20966046_ChIP-Seq_HELA_Human1.97684354
35TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.93336911
36ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.93003359
37TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.90157151
38TCF7_22412390_ChIP-Seq_EML_Mouse1.88856352
39STAT6_21828071_ChIP-Seq_BEAS2B_Human1.79304680
40RACK7_27058665_Chip-Seq_MCF-7_Human1.77491468
41ERG_21242973_ChIP-ChIP_JURKAT_Human1.76261193
42SA1_27219007_Chip-Seq_ERYTHROID_Human1.69241927
43MYC_22102868_ChIP-Seq_BL_Human1.68099277
44* KDM2B_26808549_Chip-Seq_JURKAT_Human1.66765998
45* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.64500216
46* TET1_21451524_ChIP-Seq_MESCs_Mouse1.64001620
47ESR2_21235772_ChIP-Seq_MCF-7_Human1.63034174
48ZNF274_21170338_ChIP-Seq_K562_Hela1.61768944
49RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.61122571
50* ELF1_20517297_ChIP-Seq_JURKAT_Human1.59363427
51UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.55336594
52VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.54345810
53GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.52956880
54KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.52791516
55ZFP281_18757296_ChIP-ChIP_E14_Mouse1.52787667
56DNAJC2_21179169_ChIP-ChIP_NT2_Human1.51883540
57E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.51174671
58CREB1_26743006_Chip-Seq_LNCaP_Human1.46912673
59RING1B_27294783_Chip-Seq_ESCs_Mouse1.46557176
60SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.46502720
61SRY_22984422_ChIP-ChIP_TESTIS_Rat1.45194845
62* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.44494977
63ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.43912606
64* KDM2B_26808549_Chip-Seq_K562_Human1.41828811
65CTBP2_25329375_ChIP-Seq_LNCAP_Human1.40249680
66CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.37824050
67AR_21572438_ChIP-Seq_LNCaP_Human1.36194558
68* BCL6_27268052_Chip-Seq_Bcells_Human1.34339064
69* BCOR_27268052_Chip-Seq_Bcells_Human1.32637562
70VDR_24763502_ChIP-Seq_THP-1_Human1.31123288
71* SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.30381857
72MAF_26560356_Chip-Seq_TH2_Human1.30372097
73* TP63_22573176_ChIP-Seq_HFKS_Human1.29520400
74SMAD4_21799915_ChIP-Seq_A2780_Human1.28469998
75TP53_22127205_ChIP-Seq_IMR90_Human1.27638882
76CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.24960477
77SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.24795132
78EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.23836513
79TP53_20018659_ChIP-ChIP_R1E_Mouse1.23458162
80WT1_25993318_ChIP-Seq_PODOCYTE_Human1.19963219
81AR_19668381_ChIP-Seq_PC3_Human1.18761620
82* PHF8_20622854_ChIP-Seq_HELA_Human1.17778176
83PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.15958718
84WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.15884737
85GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.15319639
86NR3C1_23031785_ChIP-Seq_PC12_Mouse1.15102064
87TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.14747937
88GATA1_19941827_ChIP-Seq_MEL_Mouse1.14320826
89CTCF_27219007_Chip-Seq_Bcells_Human1.14168589
90PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.14074738
91CTBP1_25329375_ChIP-Seq_LNCAP_Human1.13917743
92* E2F1_20622854_ChIP-Seq_HELA_Human1.13397286
93PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.13365296
94SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.13058475
95MAF_26560356_Chip-Seq_TH1_Human1.12140764
96SOX2_21211035_ChIP-Seq_LN229_Gbm1.12110389
97TET1_21490601_ChIP-Seq_MESCs_Mouse1.11903582
98RING1B_27294783_Chip-Seq_NPCs_Mouse1.10609459
99RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.10297122
100RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.09559377
101TP53_23651856_ChIP-Seq_MEFs_Mouse1.08453867
102ZFP281_27345836_Chip-Seq_ESCs_Mouse1.06703176
103P300_27058665_Chip-Seq_ZR-75-30cells_Human1.06466042
104MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.06101564
105SA1_27219007_Chip-Seq_Bcells_Human1.05627787
106RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.05072471
107TAF15_26573619_Chip-Seq_HEK293_Human1.03874128
108* JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.02576375
109TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.02164735
110RARB_24833708_ChIP-Seq_LIVER_Mouse1.00770121
111CTCF_20526341_ChIP-Seq_ESCs_Human0.99977678
112CBX2_27304074_Chip-Seq_ESCs_Mouse0.99161067
113UTX_26944678_Chip-Seq_JUKART_Human0.98764051
114PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.98466921
115SMAD3_21741376_ChIP-Seq_ESCs_Human0.96881781
116STAT3_23295773_ChIP-Seq_U87_Human0.96454992
117KLF4_19829295_ChIP-Seq_ESCs_Human0.95082956
118AR_25329375_ChIP-Seq_VCAP_Human0.94852663
119* TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.92440258
120SMAD3_21741376_ChIP-Seq_EPCs_Human0.92160772
121OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.91769198
122* KDM2B_26808549_Chip-Seq_SUP-B15_Human0.90880872
123TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.90684775
124TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.90370566
125* SMC4_20622854_ChIP-Seq_HELA_Human0.89677984
126P53_22127205_ChIP-Seq_FIBROBLAST_Human0.89470524
127ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.88063604
128SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.87126609
129TCF4_23295773_ChIP-Seq_U87_Human0.86651104
130YAP1_20516196_ChIP-Seq_MESCs_Mouse0.86161514
131LXR_22292898_ChIP-Seq_THP-1_Human0.85183329
132DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.84980657
133OCT4_19829295_ChIP-Seq_ESCs_Human0.84899494
134SMAD4_21741376_ChIP-Seq_HESCs_Human0.84891150
135GATA1_26923725_Chip-Seq_HPCs_Mouse0.84638434
136RNF2_27304074_Chip-Seq_NSC_Mouse0.84187671
137BMI1_23680149_ChIP-Seq_NPCS_Mouse0.82621691
138THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.82264511
139TOP2B_26459242_ChIP-Seq_MCF-7_Human0.80858553
140SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.80062778
141MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.78870871
142SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.77259482
143TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.76991092
144P300_19829295_ChIP-Seq_ESCs_Human0.76983931
145CDX2_19796622_ChIP-Seq_MESCs_Mouse0.76926660
146SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.75673003
147ELK4_26923725_Chip-Seq_MESODERM_Mouse0.75220815
148SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.74658358
149SMAD4_21741376_ChIP-Seq_EPCs_Human0.73783617
150* SMAD4_21741376_ChIP-Seq_ESCs_Human0.73739447

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.38139859
2MP0003880_abnormal_central_pattern4.42257715
3MP0003635_abnormal_synaptic_transmissio4.05681909
4MP0004270_analgesia3.55859632
5MP0009745_abnormal_behavioral_response3.32236061
6MP0009046_muscle_twitch3.28445354
7MP0002064_seizures3.15942061
8MP0002822_catalepsy3.14368247
9MP0002063_abnormal_learning/memory/cond3.13809708
10MP0001968_abnormal_touch/_nociception2.95891171
11MP0005423_abnormal_somatic_nervous2.92532031
12MP0002272_abnormal_nervous_system2.64566394
13MP0002572_abnormal_emotion/affect_behav2.61831944
14MP0002734_abnormal_mechanical_nocicepti2.56977096
15MP0003705_abnormal_hypodermis_morpholog2.50544912
16MP0001486_abnormal_startle_reflex2.45708069
17MP0001348_abnormal_lacrimal_gland2.39623351
18MP0008260_abnormal_autophagy2.20933598
19MP0004858_abnormal_nervous_system2.18093667
20MP0002736_abnormal_nociception_after2.17193061
21MP0008569_lethality_at_weaning2.14749232
22MP0002735_abnormal_chemical_nociception2.12150957
23MP0001501_abnormal_sleep_pattern2.11944177
24MP0002909_abnormal_adrenal_gland2.08403984
25MP0002733_abnormal_thermal_nociception2.07531089
26MP0003329_amyloid_beta_deposits2.06199187
27MP0001440_abnormal_grooming_behavior2.02353129
28MP0001958_emphysema2.01090877
29MP0004130_abnormal_muscle_cell1.98852505
30MP0001970_abnormal_pain_threshold1.95089737
31MP0002067_abnormal_sensory_capabilities1.94472983
32MP0004811_abnormal_neuron_physiology1.89231595
33MP0003279_aneurysm1.85014504
34MP0002249_abnormal_larynx_morphology1.83808282
35MP0004381_abnormal_hair_follicle1.81793273
36MP0005410_abnormal_fertilization1.76765499
37MP0005171_absent_coat_pigmentation1.75609385
38MP0002184_abnormal_innervation1.72847448
39MP0000955_abnormal_spinal_cord1.69775764
40MP0006276_abnormal_autonomic_nervous1.68995706
41MP0002557_abnormal_social/conspecific_i1.68884375
42MP0005409_darkened_coat_color1.65603092
43MP0005058_abnormal_lysosome_morphology1.64600141
44MP0003436_decreased_susceptibility_to1.63665096
45MP0005386_behavior/neurological_phenoty1.62454633
46MP0004924_abnormal_behavior1.62454633
47MP0005646_abnormal_pituitary_gland1.61192701
48MP0001986_abnormal_taste_sensitivity1.60733119
49MP0009780_abnormal_chondrocyte_physiolo1.58985599
50MP0004885_abnormal_endolymph1.56822377
51MP0000778_abnormal_nervous_system1.52230447
52MP0003122_maternal_imprinting1.52060261
53MP0002066_abnormal_motor_capabilities/c1.45132744
54MP0003879_abnormal_hair_cell1.44441739
55MP0001984_abnormal_olfaction1.44249223
56MP0000751_myopathy1.43635970
57MP0000015_abnormal_ear_pigmentation1.42558634
58MP0002882_abnormal_neuron_morphology1.42304693
59MP0000678_abnormal_parathyroid_gland1.40894870
60MP0003633_abnormal_nervous_system1.40271986
61MP0004142_abnormal_muscle_tone1.39119623
62MP0009278_abnormal_bone_marrow1.37904019
63MP0003787_abnormal_imprinting1.34614075
64MP0001849_ear_inflammation1.31323346
65MP0003283_abnormal_digestive_organ1.28478661
66MP0001529_abnormal_vocalization1.27870661
67MP0005645_abnormal_hypothalamus_physiol1.27280789
68MP0000013_abnormal_adipose_tissue1.22032503
69MP0009840_abnormal_foam_cell1.18933614
70MP0004145_abnormal_muscle_electrophysio1.18343219
71MP0003631_nervous_system_phenotype1.17244860
72MP0001905_abnormal_dopamine_level1.15304714
73MP0002152_abnormal_brain_morphology1.13079236
74MP0008961_abnormal_basal_metabolism1.12031107
75MP0001502_abnormal_circadian_rhythm1.09481301
76MP0005623_abnormal_meninges_morphology1.08357912
77MP0008872_abnormal_physiological_respon1.07627793
78MP0000681_abnormal_thyroid_gland1.05391811
79MP0002229_neurodegeneration1.04840047
80MP0003045_fibrosis1.04724078
81MP0000003_abnormal_adipose_tissue1.01050955
82MP0003690_abnormal_glial_cell0.98726186
83MP0004233_abnormal_muscle_weight0.98205304
84MP0005670_abnormal_white_adipose0.97749953
85MP0003634_abnormal_glial_cell0.95449004
86MP0002069_abnormal_eating/drinking_beha0.92944239
87MP0000920_abnormal_myelination0.92700019
88MP0002653_abnormal_ependyma_morphology0.91012570
89MP0000759_abnormal_skeletal_muscle0.90374079
90MP0003303_peritoneal_inflammation0.89797884
91MP0002933_joint_inflammation0.89618319
92MP0008874_decreased_physiological_sensi0.87328655
93MP0003632_abnormal_nervous_system0.85701840
94MP0000604_amyloidosis0.85366245
95MP0001177_atelectasis0.83918949
96MP0004085_abnormal_heartbeat0.83755889
97MP0004510_myositis0.82979969
98MP0003075_altered_response_to0.82750286
99MP0005167_abnormal_blood-brain_barrier0.82178321
100MP0008877_abnormal_DNA_methylation0.82086066
101MP0005595_abnormal_vascular_smooth0.81378186
102MP0000569_abnormal_digit_pigmentation0.81298510
103MP0005375_adipose_tissue_phenotype0.81057177
104MP0003698_abnormal_male_reproductive0.79600880
105MP0005535_abnormal_body_temperature0.79086582
106MP0001299_abnormal_eye_distance/0.77401370
107MP0005551_abnormal_eye_electrophysiolog0.77303293
108MP0001188_hyperpigmentation0.77160596
109MP0004742_abnormal_vestibular_system0.76655098
110MP0000685_abnormal_immune_system0.74411737
111MP0003137_abnormal_impulse_conducting0.74116651
112MP0002752_abnormal_somatic_nervous0.74045184
113MP0005076_abnormal_cell_differentiation0.71750775
114MP0000733_abnormal_muscle_development0.71642307
115MP0006138_congestive_heart_failure0.70955677
116MP0005394_taste/olfaction_phenotype0.70491052
117MP0005499_abnormal_olfactory_system0.70491052
118MP0001873_stomach_inflammation0.70349642
119MP0000747_muscle_weakness0.69807409
120MP0009384_cardiac_valve_regurgitation0.68865532
121MP0005451_abnormal_body_composition0.68664304
122MP0000750_abnormal_muscle_regeneration0.68155772
123MP0001963_abnormal_hearing_physiology0.68096263
124MP0008438_abnormal_cutaneous_collagen0.67054353
125MP0003763_abnormal_thymus_physiology0.66368226
126MP0010386_abnormal_urinary_bladder0.66355336
127MP0000631_abnormal_neuroendocrine_gland0.65954735
128MP0001270_distended_abdomen0.65917506
129MP0005174_abnormal_tail_pigmentation0.64668947
130MP0002090_abnormal_vision0.64324185
131MP0004043_abnormal_pH_regulation0.64155891
132MP0005666_abnormal_adipose_tissue0.63430385
133MP0002932_abnormal_joint_morphology0.63111365
134MP0002638_abnormal_pupillary_reflex0.62724887
135MP0003091_abnormal_cell_migration0.62465795
136MP0003191_abnormal_cellular_cholesterol0.60546087
137MP0003861_abnormal_nervous_system0.60130937
138MP0001943_abnormal_respiration0.58380399
139MP0004215_abnormal_myocardial_fiber0.58117463
140MP0010769_abnormal_survival0.57847667
141MP0003646_muscle_fatigue0.57731263
142MP0002837_dystrophic_cardiac_calcinosis0.57545898
143MP0001485_abnormal_pinna_reflex0.57414089
144MP0000534_abnormal_ureter_morphology0.56526484
145MP0003172_abnormal_lysosome_physiology0.56297740

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)7.16625659
2Focal motor seizures (HP:0011153)6.37899517
3Focal seizures (HP:0007359)5.24017200
4Visual hallucinations (HP:0002367)5.11776462
5Obstructive sleep apnea (HP:0002870)4.97404673
6Action tremor (HP:0002345)4.39237397
7Progressive cerebellar ataxia (HP:0002073)4.18295692
8Atonic seizures (HP:0010819)4.14412919
9Supranuclear gaze palsy (HP:0000605)3.98615160
10Stridor (HP:0010307)3.87255426
11Ankle clonus (HP:0011448)3.86450157
12Febrile seizures (HP:0002373)3.74611784
13Abnormality of the lower motor neuron (HP:0002366)3.70070234
14Epileptic encephalopathy (HP:0200134)3.65933277
15Absence seizures (HP:0002121)3.60427632
16Generalized tonic-clonic seizures (HP:0002069)3.43568929
17Depression (HP:0000716)3.40184585
18Impaired vibration sensation in the lower limbs (HP:0002166)3.39604676
19Dialeptic seizures (HP:0011146)3.18628020
20Postural instability (HP:0002172)3.18119166
21Dysdiadochokinesis (HP:0002075)3.12445195
22Gaze-evoked nystagmus (HP:0000640)3.09633153
23Abnormal eating behavior (HP:0100738)3.03835470
24Poor eye contact (HP:0000817)3.03260391
25Truncal ataxia (HP:0002078)3.02923087
26Urinary bladder sphincter dysfunction (HP:0002839)2.98540678
27Cerebral aneurysm (HP:0004944)2.95360141
28Anxiety (HP:0000739)2.94954582
29Dysmetria (HP:0001310)2.94879112
30Ventricular fibrillation (HP:0001663)2.89345032
31Urinary urgency (HP:0000012)2.85106749
32Broad face (HP:0000283)2.81036268
33Abnormal social behavior (HP:0012433)2.80156332
34Impaired social interactions (HP:0000735)2.80156332
35Spastic gait (HP:0002064)2.79916860
36Insomnia (HP:0100785)2.77426779
37Hemiplegia (HP:0002301)2.73420804
38Torticollis (HP:0000473)2.72597947
39Mutism (HP:0002300)2.72349105
40Pheochromocytoma (HP:0002666)2.69569505
41Papilledema (HP:0001085)2.67945936
42Hemiparesis (HP:0001269)2.67087985
43Impaired smooth pursuit (HP:0007772)2.66935543
44Annular pancreas (HP:0001734)2.62910955
45Broad-based gait (HP:0002136)2.62492731
46Absent/shortened dynein arms (HP:0200106)2.61241466
47Dynein arm defect of respiratory motile cilia (HP:0012255)2.61241466
48Increased variability in muscle fiber diameter (HP:0003557)2.58439377
49Difficulty climbing stairs (HP:0003551)2.57889571
50Intention tremor (HP:0002080)2.57470612
51Dysmetric saccades (HP:0000641)2.56597290
52Protrusio acetabuli (HP:0003179)2.56063223
53Neurofibrillary tangles (HP:0002185)2.52669035
54Abnormality of ocular smooth pursuit (HP:0000617)2.48631456
55Bradykinesia (HP:0002067)2.48629142
56Turricephaly (HP:0000262)2.48628668
57Focal dystonia (HP:0004373)2.47346363
58Amblyopia (HP:0000646)2.43911943
59Termporal pattern (HP:0011008)2.42990570
60Insidious onset (HP:0003587)2.42990570
61Abnormality of the aortic arch (HP:0012303)2.42215554
62Cerebral inclusion bodies (HP:0100314)2.41203206
63Scanning speech (HP:0002168)2.40813563
64Lower limb muscle weakness (HP:0007340)2.36156145
65Bundle branch block (HP:0011710)2.36025674
66Progressive inability to walk (HP:0002505)2.35737780
67Pointed chin (HP:0000307)2.35448180
68Abnormality of mucopolysaccharide metabolism (HP:0011020)2.33489772
69Abnormality of polysaccharide metabolism (HP:0011012)2.33489772
70Abnormality of glycosaminoglycan metabolism (HP:0004371)2.33489772
71Megalencephaly (HP:0001355)2.32881528
72Sleep apnea (HP:0010535)2.32869499
73Neuroendocrine neoplasm (HP:0100634)2.31895025
74Ulnar bowing (HP:0003031)2.31615433
75Limb dystonia (HP:0002451)2.30254093
76Exercise-induced myalgia (HP:0003738)2.30183465
77Distal upper limb amyotrophy (HP:0007149)2.29654544
78Upper limb amyotrophy (HP:0009129)2.29654544
79Genetic anticipation (HP:0003743)2.28801256
80Spinal canal stenosis (HP:0003416)2.28250709
81Myopathic facies (HP:0002058)2.27253154
82Status epilepticus (HP:0002133)2.27252416
83Craniofacial dystonia (HP:0012179)2.27072311
84Shallow orbits (HP:0000586)2.25922289
85Mitral regurgitation (HP:0001653)2.25724044
86Joint stiffness (HP:0001387)2.24087292
87Clonus (HP:0002169)2.23313225
88Impaired vibratory sensation (HP:0002495)2.23309603
89Dysostosis multiplex (HP:0000943)2.20903209
90Mucopolysacchariduria (HP:0008155)2.18639346
91Urinary glycosaminoglycan excretion (HP:0003541)2.18639346
92Amyotrophic lateral sclerosis (HP:0007354)2.16130814
93Ocular albinism (HP:0001107)2.16074056
94Bronchomalacia (HP:0002780)2.13806489
95Failure to thrive in infancy (HP:0001531)2.13372575
96Abnormality of saccadic eye movements (HP:0000570)2.12926795
97Cervical subluxation (HP:0003308)2.11738633
98Diplopia (HP:0000651)2.10312610
99Abnormality of binocular vision (HP:0011514)2.10312610
100Resting tremor (HP:0002322)2.10009920
101Neoplasm of the heart (HP:0100544)2.10009166
102Lymphangioma (HP:0100764)2.07040822
103Emphysema (HP:0002097)2.06729185
104Neuronal loss in central nervous system (HP:0002529)2.06277435
105Rapidly progressive (HP:0003678)2.05945950
106Increased connective tissue (HP:0009025)2.05730083
107Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.03469510
108Easy fatigability (HP:0003388)2.02529733
109Slender build (HP:0001533)2.02525086
110Type 1 muscle fiber predominance (HP:0003803)2.02335955
111Abnormality of skeletal muscle fiber size (HP:0012084)2.01127182
112Spinal rigidity (HP:0003306)2.00285364
113Asymmetric septal hypertrophy (HP:0001670)2.00243773
114Thin bony cortex (HP:0002753)2.00215761
115Stereotypic behavior (HP:0000733)2.00174910
116Abnormality of the corticospinal tract (HP:0002492)1.97358365
117Deep palmar crease (HP:0006191)1.96186717
118Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.95849930
119Nuclear cataract (HP:0100018)1.95825715
120Hypoventilation (HP:0002791)1.95416312
121Gait ataxia (HP:0002066)1.94820612
122Agitation (HP:0000713)1.94718299
123Polyphagia (HP:0002591)1.93894104
124Neoplasm of the peripheral nervous system (HP:0100007)1.92600019
125Hyperacusis (HP:0010780)1.92415676
126J-shaped sella turcica (HP:0002680)1.92265949
127Aortic regurgitation (HP:0001659)1.92241477
128Broad metatarsal (HP:0001783)1.91402076
129Abnormal EKG (HP:0003115)1.91336364
130Rigidity (HP:0002063)1.90926104
131Hypercortisolism (HP:0001578)1.90608259
132Tetraplegia (HP:0002445)1.90519351
133Supernumerary nipples (HP:0002558)1.88536697
134Akinesia (HP:0002304)1.88007348
135Distal lower limb amyotrophy (HP:0008944)1.87469542
136Genu recurvatum (HP:0002816)1.86432183
137Round ear (HP:0100830)1.86239847
138Incomplete penetrance (HP:0003829)1.86049324
139Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.85097215
140Iris hypopigmentation (HP:0007730)1.84021250
141Abnormal respiratory motile cilium physiology (HP:0012261)1.82012921
142Fetal akinesia sequence (HP:0001989)1.81989619
143Delusions (HP:0000746)1.81293207
144Drooling (HP:0002307)1.81124878
145Excessive salivation (HP:0003781)1.81124878
146Peripheral hypomyelination (HP:0007182)1.80853483
147EEG with generalized epileptiform discharges (HP:0011198)1.80597172
148Epileptiform EEG discharges (HP:0011182)1.79389884
149Germ cell neoplasia (HP:0100728)1.79348188
150Wrist flexion contracture (HP:0001239)1.79025252
151Lower limb amyotrophy (HP:0007210)1.78902284
152Hammertoe (HP:0001765)1.77595240
153Slow progression (HP:0003677)1.76654392
154Hyperthyroidism (HP:0000836)1.74551939
155Premature skin wrinkling (HP:0100678)1.73237609
156Mildly elevated creatine phosphokinase (HP:0008180)1.71830218
157EMG: neuropathic changes (HP:0003445)1.71237759
158Clumsiness (HP:0002312)1.69425583
159Distal lower limb muscle weakness (HP:0009053)1.69112983
160Difficulty running (HP:0009046)1.68393978
161Fragile skin (HP:0001030)1.67675908
162Narrow nasal bridge (HP:0000446)1.65863280
163Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.63878553
164Hand muscle atrophy (HP:0009130)1.63449634
165Aneurysm (HP:0002617)1.62752509
166Atelectasis (HP:0100750)1.62543138

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.12778338
2MAP3K93.93866178
3TRIB33.89341362
4EPHA43.46810674
5PRKD33.22445636
6MINK12.83935956
7MAP3K42.73766895
8SIK12.72425863
9PAK62.56827913
10MARK12.33903157
11KSR22.28874000
12NTRK12.27173900
13CAMKK12.20292464
14NTRK22.19999351
15DAPK22.16542050
16ERN12.14109153
17MAP2K71.92360147
18MAP4K11.87723685
19STK381.87090145
20PRKD21.85043137
21MAP2K41.78733973
22TTN1.69108042
23EEF2K1.65556937
24LMTK21.58427999
25MAP3K111.57882412
26CDK51.53154682
27MAP3K121.50408905
28SMG11.46531507
29UHMK11.43426734
30TYRO31.39880209
31ARAF1.39721072
32MAPK121.39531785
33KSR11.39419446
34CAMKK21.39295717
35PNCK1.38843697
36RIPK41.35635654
37RPS6KA21.35085175
38CDK191.32293883
39MAP2K31.28834967
40PHKG21.24103073
41PHKG11.24103073
42MAPK151.23457067
43LATS21.21396002
44PDK31.20682949
45PDK41.20682949
46MAP2K61.20477090
47TAOK11.19391656
48GRK51.18566849
49PRKCG1.14667637
50ICK1.13947373
51SIK21.13869187
52HIPK21.13632071
53FES1.10170417
54EPHB11.09269485
55PRKCH1.08460154
56DAPK11.07610164
57PINK11.07488743
58MAP3K131.06222126
59DYRK1B1.04550425
60MAP3K21.03536565
61WNK11.03382937
62CDK151.02011547
63CDK181.01895277
64ALK0.97517384
65MAPK130.96777129
66CDK140.96161939
67TNIK0.95771457
68STK110.95399389
69SGK2230.94537815
70SGK4940.94537815
71CAMK10.94408349
72RPS6KC10.93363336
73RPS6KL10.93363336
74GRK60.92768330
75PTK2B0.90799036
76CDK11A0.90458816
77RET0.89906722
78TNK20.87986318
79RPS6KA60.86044048
80MAP3K60.85236121
81RIPK10.84214358
82PLK20.83864842
83CAMK1G0.83744732
84NEK10.83213109
85ZAP700.80751135
86PRPF4B0.80256651
87PAK30.78158040
88TYK20.76123905
89SIK30.74896237
90TESK10.74610926
91CAMK2A0.74236954
92MAPK70.73821676
93PDK10.72135245
94PKN20.71668982
95TBK10.70926828
96EPHB20.70880575
97PTK60.69609749
98MAP3K10.68727166
99MTOR0.68685439
100MARK20.66664448
101CDC42BPA0.65810808
102BRSK10.65287437
103PDPK10.64868872
104SCYL20.64647692
105WNK40.63928375
106MAPKAPK30.63064043
107OXSR10.62398885
108SGK30.61599914
109TAOK20.60851369
110CAMK2B0.59825702
111RAF10.58682028
112PIM20.58511979
113PRKD10.58316000
114SGK20.57376733
115STK390.57183290
116MAP2K20.55507703
117LIMK10.55268916
118MAPK40.54365173
119RPS6KA30.53134110
120PRKG20.52713015
121MAPK100.51297768
122PDK20.50711089
123PRKAA10.50593671
124PDGFRA0.49445385
125SGK10.49318680
126PKN10.48917613
127FGFR40.48445570
128CAMK2G0.48376991
129BTK0.48073839
130MAPK110.48016715
131DYRK1A0.47340687
132PRKCZ0.47201755
133HCK0.47189663
134IRAK40.47066621
135CAMK40.46738662
136PTK20.46457565
137FGFR20.44612846
138NEK60.43941629
139MAPK80.43827495
140CASK0.43572374
141ROCK20.43184090
142DAPK30.42199870
143MAP3K70.41932303
144FER0.41740047
145CAMK2D0.40591264
146WNK30.40131113
147FYN0.40128562
148PDGFRB0.39985841
149IRAK20.39932885
150MAP3K30.39567197
151MAPKAPK50.39495816

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047213.44626574
2Nicotine addiction_Homo sapiens_hsa050333.35173454
3Olfactory transduction_Homo sapiens_hsa047402.81995370
4GABAergic synapse_Homo sapiens_hsa047272.67218142
5Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.63226864
6Circadian entrainment_Homo sapiens_hsa047132.57575087
7Long-term potentiation_Homo sapiens_hsa047202.49782896
8Glutamatergic synapse_Homo sapiens_hsa047242.42024037
9Amphetamine addiction_Homo sapiens_hsa050312.36551335
10Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.35989248
11Morphine addiction_Homo sapiens_hsa050322.34032204
12Salivary secretion_Homo sapiens_hsa049702.12945441
13Dopaminergic synapse_Homo sapiens_hsa047282.10149928
14Insulin secretion_Homo sapiens_hsa049112.06158335
15Gastric acid secretion_Homo sapiens_hsa049711.97028395
16Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.90107071
17Cholinergic synapse_Homo sapiens_hsa047251.84215444
18Aldosterone synthesis and secretion_Homo sapiens_hsa049251.84167887
19Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.81581353
20Nitrogen metabolism_Homo sapiens_hsa009101.76641427
21Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.71377748
22Cocaine addiction_Homo sapiens_hsa050301.70480661
23Other glycan degradation_Homo sapiens_hsa005111.68038944
24Taste transduction_Homo sapiens_hsa047421.66604524
25Renin secretion_Homo sapiens_hsa049241.63798187
26Oxytocin signaling pathway_Homo sapiens_hsa049211.59016944
27Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.53887890
28Calcium signaling pathway_Homo sapiens_hsa040201.52494575
29Long-term depression_Homo sapiens_hsa047301.49719689
30Notch signaling pathway_Homo sapiens_hsa043301.48085357
31Glycosaminoglycan degradation_Homo sapiens_hsa005311.46266155
32Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.42906213
33GnRH signaling pathway_Homo sapiens_hsa049121.42553184
34Gap junction_Homo sapiens_hsa045401.40969018
35Serotonergic synapse_Homo sapiens_hsa047261.36266001
36Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.29731726
37cAMP signaling pathway_Homo sapiens_hsa040241.23212040
38Estrogen signaling pathway_Homo sapiens_hsa049151.22589936
39Cardiac muscle contraction_Homo sapiens_hsa042601.22560260
40Acute myeloid leukemia_Homo sapiens_hsa052211.21655480
41Type II diabetes mellitus_Homo sapiens_hsa049301.20042878
42Phosphatidylinositol signaling system_Homo sapiens_hsa040701.16761172
43Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.15535444
44Collecting duct acid secretion_Homo sapiens_hsa049661.14448380
45Oocyte meiosis_Homo sapiens_hsa041141.12117312
46Glioma_Homo sapiens_hsa052141.09510842
47Dorso-ventral axis formation_Homo sapiens_hsa043201.05955191
48Cyanoamino acid metabolism_Homo sapiens_hsa004601.04369971
49Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.02570154
50Melanogenesis_Homo sapiens_hsa049161.01253758
51B cell receptor signaling pathway_Homo sapiens_hsa046621.00643527
52cGMP-PKG signaling pathway_Homo sapiens_hsa040220.99662747
53Chronic myeloid leukemia_Homo sapiens_hsa052200.95376616
54Osteoclast differentiation_Homo sapiens_hsa043800.92860255
55Phospholipase D signaling pathway_Homo sapiens_hsa040720.91843051
56ErbB signaling pathway_Homo sapiens_hsa040120.91828945
57Axon guidance_Homo sapiens_hsa043600.91772562
58Vascular smooth muscle contraction_Homo sapiens_hsa042700.89644514
59Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.87629517
60Pancreatic secretion_Homo sapiens_hsa049720.87266181
61Thyroid hormone synthesis_Homo sapiens_hsa049180.86235108
62Glucagon signaling pathway_Homo sapiens_hsa049220.83700983
63AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.82674732
64Carbohydrate digestion and absorption_Homo sapiens_hsa049730.82118698
65T cell receptor signaling pathway_Homo sapiens_hsa046600.81266058
66Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.79946037
67AMPK signaling pathway_Homo sapiens_hsa041520.79535076
68Dilated cardiomyopathy_Homo sapiens_hsa054140.79142687
69Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.78749904
70Vibrio cholerae infection_Homo sapiens_hsa051100.76511927
71Focal adhesion_Homo sapiens_hsa045100.76464287
72Adipocytokine signaling pathway_Homo sapiens_hsa049200.75914525
73Bile secretion_Homo sapiens_hsa049760.71760283
74Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.70639245
75Neurotrophin signaling pathway_Homo sapiens_hsa047220.70359903
76Sulfur relay system_Homo sapiens_hsa041220.69865344
77Insulin resistance_Homo sapiens_hsa049310.68144071
78Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.67998214
79MAPK signaling pathway_Homo sapiens_hsa040100.66255572
80Prolactin signaling pathway_Homo sapiens_hsa049170.66142494
81Thyroid hormone signaling pathway_Homo sapiens_hsa049190.64766541
82ABC transporters_Homo sapiens_hsa020100.64638541
83Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.64281015
84Endocytosis_Homo sapiens_hsa041440.63731775
85VEGF signaling pathway_Homo sapiens_hsa043700.63233048
86Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.62920966
87Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.62369176
88Alcoholism_Homo sapiens_hsa050340.62204160
89Lysosome_Homo sapiens_hsa041420.61031061
90ECM-receptor interaction_Homo sapiens_hsa045120.60885752
91Choline metabolism in cancer_Homo sapiens_hsa052310.60153564
92FoxO signaling pathway_Homo sapiens_hsa040680.57739052
93Chemokine signaling pathway_Homo sapiens_hsa040620.57002344
94Platelet activation_Homo sapiens_hsa046110.56303979
95Toxoplasmosis_Homo sapiens_hsa051450.55995650
96Inositol phosphate metabolism_Homo sapiens_hsa005620.55215916
97Phototransduction_Homo sapiens_hsa047440.54821804
98Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.54603488
99mTOR signaling pathway_Homo sapiens_hsa041500.54226227
100TNF signaling pathway_Homo sapiens_hsa046680.52746099
101Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.52227692
102Rap1 signaling pathway_Homo sapiens_hsa040150.52079579
103Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.51975852
104Insulin signaling pathway_Homo sapiens_hsa049100.51904212
105Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.51814837
106Ras signaling pathway_Homo sapiens_hsa040140.45904964
107Central carbon metabolism in cancer_Homo sapiens_hsa052300.45099665
108Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.44174543
109Sphingolipid signaling pathway_Homo sapiens_hsa040710.44150260
110Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.44129228
111Fatty acid biosynthesis_Homo sapiens_hsa000610.42625948
112Longevity regulating pathway - mammal_Homo sapiens_hsa042110.42398814
113Type I diabetes mellitus_Homo sapiens_hsa049400.42302849
114Prion diseases_Homo sapiens_hsa050200.41302170
115Non-small cell lung cancer_Homo sapiens_hsa052230.40148496
116Wnt signaling pathway_Homo sapiens_hsa043100.39790021
117Endometrial cancer_Homo sapiens_hsa052130.39683350
118Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.38876884
119Glycerophospholipid metabolism_Homo sapiens_hsa005640.38288921
120Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.38020284
121Renal cell carcinoma_Homo sapiens_hsa052110.33961161
122Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.33431495
123Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.32926069
124Hedgehog signaling pathway_Homo sapiens_hsa043400.30194481
125Circadian rhythm_Homo sapiens_hsa047100.28981573
126Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.28161335
127Ovarian steroidogenesis_Homo sapiens_hsa049130.26014348
128SNARE interactions in vesicular transport_Homo sapiens_hsa041300.25247358

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