Rank | Gene Set | Z-score |
---|---|---|
1 | L-phenylalanine catabolic process (GO:0006559) | 7.45323506 |
2 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 7.45323506 |
3 | L-phenylalanine metabolic process (GO:0006558) | 7.11941638 |
4 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 7.11941638 |
5 | aromatic amino acid family catabolic process (GO:0009074) | 6.77309542 |
6 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 6.26128965 |
7 | epoxygenase P450 pathway (GO:0019373) | 6.19623516 |
8 | indole-containing compound catabolic process (GO:0042436) | 6.17794093 |
9 | indolalkylamine catabolic process (GO:0046218) | 6.17794093 |
10 | tryptophan catabolic process (GO:0006569) | 6.17794093 |
11 | kynurenine metabolic process (GO:0070189) | 5.99201445 |
12 | bile acid biosynthetic process (GO:0006699) | 5.87222012 |
13 | tryptophan metabolic process (GO:0006568) | 5.79933721 |
14 | urea cycle (GO:0000050) | 5.66537033 |
15 | urea metabolic process (GO:0019627) | 5.66537033 |
16 | glyoxylate metabolic process (GO:0046487) | 5.65136511 |
17 | alpha-linolenic acid metabolic process (GO:0036109) | 5.55050828 |
18 | high-density lipoprotein particle remodeling (GO:0034375) | 5.38699011 |
19 | negative regulation of fibrinolysis (GO:0051918) | 5.37994185 |
20 | complement activation, alternative pathway (GO:0006957) | 5.34252990 |
21 | regulation of protein activation cascade (GO:2000257) | 5.28567687 |
22 | negative regulation of protein activation cascade (GO:2000258) | 5.27082908 |
23 | cysteine metabolic process (GO:0006534) | 5.21930199 |
24 | nitrogen cycle metabolic process (GO:0071941) | 5.21236846 |
25 | sulfur amino acid catabolic process (GO:0000098) | 5.20533484 |
26 | regulation of fibrinolysis (GO:0051917) | 5.20350767 |
27 | peptidyl-glutamic acid carboxylation (GO:0017187) | 5.19811184 |
28 | protein carboxylation (GO:0018214) | 5.19811184 |
29 | omega-hydroxylase P450 pathway (GO:0097267) | 5.13864044 |
30 | bile acid metabolic process (GO:0008206) | 5.01597961 |
31 | regulation of triglyceride catabolic process (GO:0010896) | 4.98289331 |
32 | intestinal cholesterol absorption (GO:0030299) | 4.98209855 |
33 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 4.97080732 |
34 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 4.96604967 |
35 | serine family amino acid catabolic process (GO:0009071) | 4.96180931 |
36 | regulation of complement activation (GO:0030449) | 4.95956033 |
37 | aromatic amino acid family metabolic process (GO:0009072) | 4.90253640 |
38 | regulation of cholesterol esterification (GO:0010872) | 4.77255601 |
39 | reverse cholesterol transport (GO:0043691) | 4.76818298 |
40 | homocysteine metabolic process (GO:0050667) | 4.76621918 |
41 | tyrosine metabolic process (GO:0006570) | 4.71337839 |
42 | protein-lipid complex assembly (GO:0065005) | 4.66206085 |
43 | protein-lipid complex remodeling (GO:0034368) | 4.65772824 |
44 | macromolecular complex remodeling (GO:0034367) | 4.65772824 |
45 | plasma lipoprotein particle remodeling (GO:0034369) | 4.65772824 |
46 | amino-acid betaine metabolic process (GO:0006577) | 4.60953575 |
47 | drug metabolic process (GO:0017144) | 4.60063271 |
48 | phospholipid efflux (GO:0033700) | 4.59646257 |
49 | ethanol metabolic process (GO:0006067) | 4.58999188 |
50 | lysine catabolic process (GO:0006554) | 4.58176615 |
51 | lysine metabolic process (GO:0006553) | 4.58176615 |
52 | acylglycerol homeostasis (GO:0055090) | 4.57161697 |
53 | triglyceride homeostasis (GO:0070328) | 4.57161697 |
54 | alpha-amino acid catabolic process (GO:1901606) | 4.56946389 |
55 | negative regulation of cholesterol transport (GO:0032375) | 4.49990549 |
56 | negative regulation of sterol transport (GO:0032372) | 4.49990549 |
57 | bile acid and bile salt transport (GO:0015721) | 4.40171491 |
58 | regulation of humoral immune response (GO:0002920) | 4.38420015 |
59 | indolalkylamine metabolic process (GO:0006586) | 4.36448840 |
60 | cellular glucuronidation (GO:0052695) | 4.32628148 |
61 | cellular ketone body metabolic process (GO:0046950) | 4.31136588 |
62 | coenzyme catabolic process (GO:0009109) | 4.28968934 |
63 | amine catabolic process (GO:0009310) | 4.27992146 |
64 | cellular biogenic amine catabolic process (GO:0042402) | 4.27992146 |
65 | negative regulation of hemostasis (GO:1900047) | 4.27219795 |
66 | negative regulation of blood coagulation (GO:0030195) | 4.27219795 |
67 | negative regulation of complement activation (GO:0045916) | 4.26617690 |
68 | regulation of plasminogen activation (GO:0010755) | 4.26050280 |
69 | protein-lipid complex subunit organization (GO:0071825) | 4.25353691 |
70 | plasma lipoprotein particle clearance (GO:0034381) | 4.23240715 |
71 | cellular amino acid catabolic process (GO:0009063) | 4.20892954 |
72 | glycine metabolic process (GO:0006544) | 4.19374800 |
73 | drug catabolic process (GO:0042737) | 4.18982912 |
74 | cholesterol efflux (GO:0033344) | 4.18226191 |
75 | imidazole-containing compound metabolic process (GO:0052803) | 4.18051581 |
76 | glutamate metabolic process (GO:0006536) | 4.15926203 |
77 | benzene-containing compound metabolic process (GO:0042537) | 4.15592695 |
78 | ethanol oxidation (GO:0006069) | 4.09739442 |
79 | serine family amino acid metabolic process (GO:0009069) | 4.05763317 |
80 | regulation of apoptotic cell clearance (GO:2000425) | 4.03794073 |
81 | cellular modified amino acid catabolic process (GO:0042219) | 4.01091806 |
82 | arginine metabolic process (GO:0006525) | 3.98503927 |
83 | lipoprotein metabolic process (GO:0042157) | 3.97742411 |
84 | plasma lipoprotein particle assembly (GO:0034377) | 3.95158600 |
85 | acute-phase response (GO:0006953) | 3.93460050 |
86 | negative regulation of coagulation (GO:0050819) | 3.92919973 |
87 | dicarboxylic acid biosynthetic process (GO:0043650) | 3.92388357 |
88 | fibrinolysis (GO:0042730) | 3.91283857 |
89 | positive regulation of lipoprotein lipase activity (GO:0051006) | 3.89477660 |
90 | positive regulation of triglyceride lipase activity (GO:0061365) | 3.89477660 |
91 | intestinal absorption (GO:0050892) | 3.88996898 |
92 | glucuronate metabolic process (GO:0019585) | 3.86316717 |
93 | uronic acid metabolic process (GO:0006063) | 3.86316717 |
94 | oxidative demethylation (GO:0070989) | 3.85497940 |
95 | aldehyde catabolic process (GO:0046185) | 3.85072946 |
96 | serine family amino acid biosynthetic process (GO:0009070) | 3.81645039 |
97 | regulation of bile acid biosynthetic process (GO:0070857) | 3.80545779 |
98 | low-density lipoprotein particle remodeling (GO:0034374) | 3.79185895 |
99 | negative regulation of wound healing (GO:0061045) | 3.76707784 |
100 | phospholipid homeostasis (GO:0055091) | 3.75765208 |
101 | cholesterol homeostasis (GO:0042632) | 3.75079532 |
102 | positive regulation of lipid catabolic process (GO:0050996) | 3.74938865 |
103 | complement activation, classical pathway (GO:0006958) | 3.74523356 |
104 | negative regulation of lipase activity (GO:0060192) | 3.73161623 |
105 | ketone body metabolic process (GO:1902224) | 3.72680511 |
106 | very-low-density lipoprotein particle assembly (GO:0034379) | 3.72031036 |
107 | positive regulation of blood coagulation (GO:0030194) | 3.71152391 |
108 | positive regulation of hemostasis (GO:1900048) | 3.71152391 |
109 | organic acid catabolic process (GO:0016054) | 3.70717771 |
110 | carboxylic acid catabolic process (GO:0046395) | 3.70717771 |
111 | complement activation (GO:0006956) | 3.70256540 |
112 | exogenous drug catabolic process (GO:0042738) | 3.70202733 |
113 | blood coagulation, intrinsic pathway (GO:0007597) | 3.70187355 |
114 | sterol homeostasis (GO:0055092) | 3.68986977 |
115 | cytolysis (GO:0019835) | 3.68568103 |
116 | cofactor catabolic process (GO:0051187) | 3.67058969 |
117 | flavonoid metabolic process (GO:0009812) | 3.66987074 |
118 | regulation of cholesterol homeostasis (GO:2000188) | 3.66684267 |
119 | protein activation cascade (GO:0072376) | 3.65909636 |
120 | acetyl-CoA metabolic process (GO:0006084) | 3.64220828 |
121 | short-chain fatty acid metabolic process (GO:0046459) | 3.63536396 |
122 | response to nitrosative stress (GO:0051409) | 3.62662393 |
123 | plasma lipoprotein particle organization (GO:0071827) | 3.56413654 |
124 | regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081) | 3.52243555 |
125 | sterol transport (GO:0015918) | 3.48569977 |
126 | cholesterol transport (GO:0030301) | 3.48569977 |
127 | negative regulation of humoral immune response (GO:0002921) | 3.46642438 |
128 | positive regulation of coagulation (GO:0050820) | 3.43399616 |
129 | killing of cells in other organism involved in symbiotic interaction (GO:0051883) | 3.37961489 |
130 | disruption of cells of other organism involved in symbiotic interaction (GO:0051818) | 3.37961489 |
131 | phenylpropanoid metabolic process (GO:0009698) | 3.37010279 |
132 | drug transmembrane transport (GO:0006855) | 3.35824696 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * RXR_22158963_ChIP-Seq_LIVER_Mouse | 8.20636244 |
2 | * PPARA_22158963_ChIP-Seq_LIVER_Mouse | 7.05206709 |
3 | * EGR1_23403033_ChIP-Seq_LIVER_Mouse | 6.86731428 |
4 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 6.41116591 |
5 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 5.19420036 |
6 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 4.93765001 |
7 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 4.80573591 |
8 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 4.03736993 |
9 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 3.86529264 |
10 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 2.02434112 |
11 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 11.6920921 |
12 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.98138148 |
13 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.94864180 |
14 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.79683259 |
15 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.62449611 |
16 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.62273072 |
17 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.60790790 |
18 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.55369965 |
19 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.51965890 |
20 | GATA1_22025678_ChIP-Seq_K562_Human | 1.48929066 |
21 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.47698094 |
22 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.47136982 |
23 | VDR_22108803_ChIP-Seq_LS180_Human | 1.46360744 |
24 | * HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.39584636 |
25 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.34834677 |
26 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.33043322 |
27 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.32538114 |
28 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.31097122 |
29 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.30162216 |
30 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.27971169 |
31 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.26996266 |
32 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.26722824 |
33 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.24036395 |
34 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.23451815 |
35 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.20318187 |
36 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.20120049 |
37 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.18690818 |
38 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.18173439 |
39 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.17890366 |
40 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.17814172 |
41 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.14674725 |
42 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 1.14046413 |
43 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.13270777 |
44 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.10942811 |
45 | TP53_16413492_ChIP-PET_HCT116_Human | 1.08697781 |
46 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.06995199 |
47 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.06105718 |
48 | STAT3_23295773_ChIP-Seq_U87_Human | 1.04310089 |
49 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.01481618 |
50 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.97696286 |
51 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.97203060 |
52 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.95562534 |
53 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.95562534 |
54 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.95529560 |
55 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.94616020 |
56 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.93856951 |
57 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.93735001 |
58 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.93135289 |
59 | TCF4_23295773_ChIP-Seq_U87_Human | 0.92981212 |
60 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.91743365 |
61 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.91078272 |
62 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.90995551 |
63 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.90534309 |
64 | * FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.89357696 |
65 | * GATA4_25053715_ChIP-Seq_YYC3_Human | 0.89203850 |
66 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.88447668 |
67 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.88441424 |
68 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.87818551 |
69 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.86976643 |
70 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.86724981 |
71 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.85991517 |
72 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.85860357 |
73 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.85047163 |
74 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.84803335 |
75 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.84423961 |
76 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.84222786 |
77 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.83791917 |
78 | P300_19829295_ChIP-Seq_ESCs_Human | 0.83513785 |
79 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.82889983 |
80 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.82639077 |
81 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.82560692 |
82 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.82299607 |
83 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 0.81511540 |
84 | TP63_23658742_ChIP-Seq_EP156T_Human | 0.81473552 |
85 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 0.81039990 |
86 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.80958557 |
87 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.77752364 |
88 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.77297678 |
89 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.74992299 |
90 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.73880387 |
91 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.73609991 |
92 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.72813892 |
93 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.72009035 |
94 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.72009035 |
95 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.71101724 |
96 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.70595827 |
97 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.69886011 |
98 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.68559955 |
99 | RARA_24833708_ChIP-Seq_LIVER_Mouse | 0.68252731 |
100 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.66798010 |
101 | * SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.64279013 |
102 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.64215256 |
103 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.63928807 |
104 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.60545981 |
105 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.59032788 |
106 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.59023602 |
107 | RARB_24833708_ChIP-Seq_LIVER_Mouse | 0.58997801 |
108 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.56501759 |
109 | AR_20517297_ChIP-Seq_VCAP_Human | 0.55948816 |
110 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.55803519 |
111 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.55640770 |
112 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.55517568 |
113 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.55351602 |
114 | STAT1_17558387_ChIP-Seq_HELA_Human | 0.52912550 |
115 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.52846848 |
116 | MYC_19915707_ChIP-ChIP_AK7_Human | 0.52418503 |
117 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.52007636 |
118 | ESET_19884257_ChIP-Seq_ESCs_Mouse | 0.50769074 |
119 | CBP_21632823_ChIP-Seq_H3396_Human | 0.50754907 |
120 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.49239580 |
121 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.49198737 |
122 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 0.48722290 |
123 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.48042577 |
124 | PPARG_20887899_ChIP-Seq_3T3-L1_Mouse | 0.47015746 |
125 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.46992061 |
126 | GATA2_19941826_ChIP-Seq_K562_Human | 0.46823087 |
127 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.46547241 |
128 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.45907016 |
129 | GATA6_25053715_ChIP-Seq_YYC3_Human | 0.45725384 |
130 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.45654378 |
131 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.44523932 |
132 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.43832007 |
133 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.43283516 |
134 | GATA1_19941826_ChIP-Seq_K562_Human | 0.42929804 |
135 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.42825607 |
136 | * GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.42622308 |
137 | * FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.42478594 |
138 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.41465609 |
139 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.41461617 |
140 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.39528258 |
141 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.37825773 |
142 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.36739384 |
143 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.36128399 |
144 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.35948867 |
145 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.35789936 |
146 | CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.35731083 |
147 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 0.35683985 |
148 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.35372977 |
149 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.35357203 |
150 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.35254422 |
151 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.35253256 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002139_abnormal_hepatobiliary_system | 8.12668945 |
2 | MP0005360_urolithiasis | 7.64988035 |
3 | MP0005085_abnormal_gallbladder_physiolo | 6.38242524 |
4 | MP0005365_abnormal_bile_salt | 6.07445724 |
5 | MP0008875_abnormal_xenobiotic_pharmacok | 5.27012581 |
6 | MP0003806_abnormal_nucleotide_metabolis | 4.08659079 |
7 | MP0003252_abnormal_bile_duct | 3.95138653 |
8 | MP0010329_abnormal_lipoprotein_level | 3.55144623 |
9 | MP0009840_abnormal_foam_cell | 3.27512686 |
10 | MP0005083_abnormal_biliary_tract | 2.91560529 |
11 | MP0005332_abnormal_amino_acid | 2.77664692 |
12 | MP0001666_abnormal_nutrient_absorption | 2.75940196 |
13 | MP0003195_calcinosis | 2.65164606 |
14 | MP0003191_abnormal_cellular_cholesterol | 2.33998103 |
15 | MP0004019_abnormal_vitamin_homeostasis | 2.25233533 |
16 | MP0000609_abnormal_liver_physiology | 2.13761794 |
17 | MP0002118_abnormal_lipid_homeostasis | 2.08808844 |
18 | MP0002138_abnormal_hepatobiliary_system | 1.97360017 |
19 | MP0003868_abnormal_feces_composition | 1.90200107 |
20 | MP0005319_abnormal_enzyme/_coenzyme | 1.82406662 |
21 | MP0001764_abnormal_homeostasis | 1.66235226 |
22 | MP0009697_abnormal_copulation | 1.58874585 |
23 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.54963707 |
24 | MP0003122_maternal_imprinting | 1.48171472 |
25 | MP0005451_abnormal_body_composition | 1.46667898 |
26 | MP0003011_delayed_dark_adaptation | 1.43613216 |
27 | MP0003183_abnormal_peptide_metabolism | 1.36742073 |
28 | MP0009643_abnormal_urine_homeostasis | 1.31364136 |
29 | MP0003186_abnormal_redox_activity | 1.26615419 |
30 | MP0003656_abnormal_erythrocyte_physiolo | 1.21501737 |
31 | MP0000598_abnormal_liver_morphology | 1.14219793 |
32 | MP0002254_reproductive_system_inflammat | 1.12573809 |
33 | MP0004043_abnormal_pH_regulation | 1.10634946 |
34 | MP0009764_decreased_sensitivity_to | 1.10584025 |
35 | MP0005647_abnormal_sex_gland | 1.10028519 |
36 | MP0003705_abnormal_hypodermis_morpholog | 1.04449865 |
37 | MP0009763_increased_sensitivity_to | 1.00746815 |
38 | MP0006054_spinal_hemorrhage | 1.00563565 |
39 | MP0000604_amyloidosis | 1.00241709 |
40 | MP0005636_abnormal_mineral_homeostasis | 0.95110907 |
41 | MP0005670_abnormal_white_adipose | 0.93258661 |
42 | MP0008469_abnormal_protein_level | 0.91478599 |
43 | MP0010368_abnormal_lymphatic_system | 0.89063965 |
44 | MP0009642_abnormal_blood_homeostasis | 0.87405371 |
45 | MP0002876_abnormal_thyroid_physiology | 0.85839418 |
46 | MP0005084_abnormal_gallbladder_morpholo | 0.85081855 |
47 | MP0005408_hypopigmentation | 0.82915833 |
48 | MP0009765_abnormal_xenobiotic_induced | 0.79719510 |
49 | MP0005376_homeostasis/metabolism_phenot | 0.78899224 |
50 | MP0006036_abnormal_mitochondrial_physio | 0.77921108 |
51 | MP0003879_abnormal_hair_cell | 0.77335138 |
52 | MP0005551_abnormal_eye_electrophysiolog | 0.76330021 |
53 | MP0002078_abnormal_glucose_homeostasis | 0.74881179 |
54 | MP0002971_abnormal_brown_adipose | 0.72874157 |
55 | MP0009780_abnormal_chondrocyte_physiolo | 0.72597020 |
56 | MP0003950_abnormal_plasma_membrane | 0.72004246 |
57 | MP0003172_abnormal_lysosome_physiology | 0.71968857 |
58 | MP0005409_darkened_coat_color | 0.70643414 |
59 | MP0001915_intracranial_hemorrhage | 0.69562336 |
60 | MP0005334_abnormal_fat_pad | 0.69430742 |
61 | MP0005220_abnormal_exocrine_pancreas | 0.69072423 |
62 | MP0004130_abnormal_muscle_cell | 0.68669411 |
63 | MP0001756_abnormal_urination | 0.68455369 |
64 | MP0005535_abnormal_body_temperature | 0.67053302 |
65 | MP0003690_abnormal_glial_cell | 0.66367479 |
66 | MP0001661_extended_life_span | 0.63032911 |
67 | MP0005266_abnormal_metabolism | 0.62930040 |
68 | MP0000566_synostosis | 0.60042793 |
69 | MP0009053_abnormal_anal_canal | 0.59188946 |
70 | MP0010155_abnormal_intestine_physiology | 0.58554770 |
71 | MP0005410_abnormal_fertilization | 0.58513810 |
72 | MP0002089_abnormal_postnatal_growth/wei | 0.57933274 |
73 | MP0005164_abnormal_response_to | 0.57623875 |
74 | MP0002822_catalepsy | 0.57544023 |
75 | MP0005448_abnormal_energy_balance | 0.56780220 |
76 | MP0003329_amyloid_beta_deposits | 0.56650553 |
77 | MP0005464_abnormal_platelet_physiology | 0.55750736 |
78 | MP0000371_diluted_coat_color | 0.54874075 |
79 | MP0003724_increased_susceptibility_to | 0.54761064 |
80 | MP0005646_abnormal_pituitary_gland | 0.54534120 |
81 | MP0001986_abnormal_taste_sensitivity | 0.53489991 |
82 | MP0000639_abnormal_adrenal_gland | 0.53328314 |
83 | MP0004147_increased_porphyrin_level | 0.52970055 |
84 | MP0002136_abnormal_kidney_physiology | 0.52536143 |
85 | MP0006035_abnormal_mitochondrial_morpho | 0.50515899 |
86 | MP0001765_abnormal_ion_homeostasis | 0.50313915 |
87 | MP0003638_abnormal_response/metabolism_ | 0.48940324 |
88 | MP0004381_abnormal_hair_follicle | 0.48934262 |
89 | MP0003436_decreased_susceptibility_to | 0.48332476 |
90 | MP0004782_abnormal_surfactant_physiolog | 0.47226828 |
91 | MP0002282_abnormal_trachea_morphology | 0.47065674 |
92 | MP0003866_abnormal_defecation | 0.47055066 |
93 | MP0002928_abnormal_bile_duct | 0.46819762 |
94 | MP0009785_altered_susceptibility_to | 0.46709870 |
95 | MP0005395_other_phenotype | 0.45473572 |
96 | MP0005666_abnormal_adipose_tissue | 0.45294685 |
97 | MP0003718_maternal_effect | 0.44752864 |
98 | MP0008873_increased_physiological_sensi | 0.44124431 |
99 | MP0002796_impaired_skin_barrier | 0.44058372 |
100 | MP0002909_abnormal_adrenal_gland | 0.44038259 |
101 | MP0002837_dystrophic_cardiac_calcinosis | 0.43927018 |
102 | MP0008874_decreased_physiological_sensi | 0.43922524 |
103 | MP0001324_abnormal_eye_pigmentation | 0.43895072 |
104 | MP0003878_abnormal_ear_physiology | 0.43800349 |
105 | MP0005377_hearing/vestibular/ear_phenot | 0.43800349 |
106 | MP0005166_decreased_susceptibility_to | 0.42799902 |
107 | MP0001501_abnormal_sleep_pattern | 0.42131959 |
108 | MP0009384_cardiac_valve_regurgitation | 0.41291162 |
109 | MP0000579_abnormal_nail_morphology | 0.39674845 |
110 | MP0003075_altered_response_to | 0.39577677 |
111 | MP0003953_abnormal_hormone_level | 0.39340002 |
112 | MP0002135_abnormal_kidney_morphology | 0.39079452 |
113 | MP0008872_abnormal_physiological_respon | 0.37791290 |
114 | MP0003633_abnormal_nervous_system | 0.37174392 |
115 | MP0000230_abnormal_systemic_arterial | 0.37021401 |
116 | MP0005248_abnormal_Harderian_gland | 0.36398380 |
117 | MP0003632_abnormal_nervous_system | 0.36251639 |
118 | MP0001853_heart_inflammation | 0.36016824 |
119 | MP0003943_abnormal_hepatobiliary_system | 0.35671036 |
120 | MP0009115_abnormal_fat_cell | 0.35566898 |
121 | MP0000249_abnormal_blood_vessel | 0.33948051 |
122 | MP0001845_abnormal_inflammatory_respons | 0.32448938 |
123 | MP0006082_CNS_inflammation | 0.32283269 |
124 | MP0004883_abnormal_blood_vessel | 0.30347909 |
125 | MP0002970_abnormal_white_adipose | 0.29386048 |
126 | MP0002132_abnormal_respiratory_system | 0.29333853 |
127 | MP0002060_abnormal_skin_morphology | 0.28776939 |
128 | MP0001243_abnormal_dermal_layer | 0.28265772 |
129 | MP0001881_abnormal_mammary_gland | 0.28117099 |
130 | MP0005167_abnormal_blood-brain_barrier | 0.27977352 |
131 | MP0004264_abnormal_extraembryonic_tissu | 0.27828537 |
132 | MP0002168_other_aberrant_phenotype | 0.27621674 |
133 | MP0005058_abnormal_lysosome_morphology | 0.27251673 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 7.28313079 |
2 | Deep venous thrombosis (HP:0002625) | 7.21053865 |
3 | Intrahepatic cholestasis (HP:0001406) | 7.18646222 |
4 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 6.68711959 |
5 | Hypobetalipoproteinemia (HP:0003563) | 6.45450401 |
6 | Prolonged partial thromboplastin time (HP:0003645) | 6.42744211 |
7 | Xanthomatosis (HP:0000991) | 6.23879764 |
8 | Complement deficiency (HP:0004431) | 5.48477844 |
9 | Hyperlipoproteinemia (HP:0010980) | 5.45646660 |
10 | Hypolipoproteinemia (HP:0010981) | 4.79369242 |
11 | Joint hemorrhage (HP:0005261) | 4.64954402 |
12 | Hyperammonemia (HP:0001987) | 4.59941653 |
13 | Epidermoid cyst (HP:0200040) | 4.51501632 |
14 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 4.38852968 |
15 | Hyperglycinemia (HP:0002154) | 4.38832566 |
16 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 4.35856046 |
17 | Abnormality of the common coagulation pathway (HP:0010990) | 4.35428144 |
18 | Ketosis (HP:0001946) | 4.23198573 |
19 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 4.20566859 |
20 | Fat malabsorption (HP:0002630) | 4.20432060 |
21 | Abnormality of methionine metabolism (HP:0010901) | 4.16817848 |
22 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 4.15259354 |
23 | Hypoalphalipoproteinemia (HP:0003233) | 4.13431765 |
24 | Hyperglycinuria (HP:0003108) | 4.04128432 |
25 | Abnormality of complement system (HP:0005339) | 3.99083479 |
26 | Abnormality of glycine metabolism (HP:0010895) | 3.97252632 |
27 | Abnormality of serine family amino acid metabolism (HP:0010894) | 3.97252632 |
28 | Conjugated hyperbilirubinemia (HP:0002908) | 3.86948174 |
29 | Hypoglycemic coma (HP:0001325) | 3.84227128 |
30 | Abnormality of pyrimidine metabolism (HP:0004353) | 3.82176368 |
31 | Abnormality of the intrinsic pathway (HP:0010989) | 3.63306066 |
32 | Hypercholesterolemia (HP:0003124) | 3.56294511 |
33 | Abnormality of fatty-acid metabolism (HP:0004359) | 3.39468760 |
34 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 3.39327514 |
35 | Hyperbilirubinemia (HP:0002904) | 3.32011584 |
36 | Steatorrhea (HP:0002570) | 3.14410785 |
37 | Abnormality of nucleobase metabolism (HP:0010932) | 3.12836407 |
38 | Abnormality of serum amino acid levels (HP:0003112) | 3.03054337 |
39 | Ketoacidosis (HP:0001993) | 3.02856934 |
40 | Delayed CNS myelination (HP:0002188) | 3.00464240 |
41 | Spontaneous abortion (HP:0005268) | 2.96627569 |
42 | Myocardial infarction (HP:0001658) | 2.90217129 |
43 | Hepatocellular carcinoma (HP:0001402) | 2.88727846 |
44 | Systemic lupus erythematosus (HP:0002725) | 2.87326181 |
45 | Purpura (HP:0000979) | 2.83277572 |
46 | Hypochromic microcytic anemia (HP:0004840) | 2.80755716 |
47 | Metabolic acidosis (HP:0001942) | 2.78620397 |
48 | Abnormality of purine metabolism (HP:0004352) | 2.78166427 |
49 | Skin nodule (HP:0200036) | 2.74521238 |
50 | Vascular calcification (HP:0004934) | 2.66114473 |
51 | Acanthocytosis (HP:0001927) | 2.66072983 |
52 | Lethargy (HP:0001254) | 2.60868548 |
53 | Dicarboxylic aciduria (HP:0003215) | 2.58923448 |
54 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.58923448 |
55 | Osteomalacia (HP:0002749) | 2.54333094 |
56 | Malnutrition (HP:0004395) | 2.51891777 |
57 | Fair hair (HP:0002286) | 2.51869080 |
58 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.50041670 |
59 | Gout (HP:0001997) | 2.48399533 |
60 | Hypoglycemic seizures (HP:0002173) | 2.47410366 |
61 | Facial shape deformation (HP:0011334) | 2.47003509 |
62 | Potter facies (HP:0002009) | 2.47003509 |
63 | Glomerulonephritis (HP:0000099) | 2.45861930 |
64 | Spastic diplegia (HP:0001264) | 2.43671296 |
65 | Abnormal gallbladder morphology (HP:0012437) | 2.41616179 |
66 | Joint swelling (HP:0001386) | 2.38535969 |
67 | Cerebral edema (HP:0002181) | 2.37985142 |
68 | Cholelithiasis (HP:0001081) | 2.36786790 |
69 | Cholecystitis (HP:0001082) | 2.35513046 |
70 | Abnormal gallbladder physiology (HP:0012438) | 2.35513046 |
71 | Mitral stenosis (HP:0001718) | 2.35133872 |
72 | Cardiovascular calcification (HP:0011915) | 2.34949782 |
73 | Irritability (HP:0000737) | 2.34261162 |
74 | Amyloidosis (HP:0011034) | 2.30392144 |
75 | Epistaxis (HP:0000421) | 2.30377163 |
76 | Pigmentary retinal degeneration (HP:0001146) | 2.29124187 |
77 | Neonatal onset (HP:0003623) | 2.27571969 |
78 | Pancreatitis (HP:0001733) | 2.24507571 |
79 | Esophageal varix (HP:0002040) | 2.22065366 |
80 | Arthropathy (HP:0003040) | 2.21593345 |
81 | Gingival bleeding (HP:0000225) | 2.18039621 |
82 | Sensorimotor neuropathy (HP:0007141) | 2.16474416 |
83 | Proximal tubulopathy (HP:0000114) | 2.15605050 |
84 | Late onset (HP:0003584) | 2.15488839 |
85 | Generalized aminoaciduria (HP:0002909) | 2.14105206 |
86 | Enlarged kidneys (HP:0000105) | 2.10922504 |
87 | Vomiting (HP:0002013) | 2.10461776 |
88 | Menorrhagia (HP:0000132) | 2.09841491 |
89 | Pulmonary embolism (HP:0002204) | 2.08392680 |
90 | Brushfield spots (HP:0001088) | 2.07458350 |
91 | Abnormal tarsal ossification (HP:0008369) | 2.05336542 |
92 | Thrombophlebitis (HP:0004418) | 2.03595311 |
93 | Poikilocytosis (HP:0004447) | 2.03239330 |
94 | Opisthotonus (HP:0002179) | 2.02046514 |
95 | Hydroxyprolinuria (HP:0003080) | 2.01401637 |
96 | Abnormality of proline metabolism (HP:0010907) | 2.01401637 |
97 | Abnormality of the gallbladder (HP:0005264) | 1.98503182 |
98 | Rickets (HP:0002748) | 1.97943985 |
99 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.97311924 |
100 | Hemorrhage of the eye (HP:0011885) | 1.96646839 |
101 | Widely patent fontanelles and sutures (HP:0004492) | 1.95816019 |
102 | Alkalosis (HP:0001948) | 1.91770644 |
103 | Renal cortical cysts (HP:0000803) | 1.88078239 |
104 | Abnormal cartilage morphology (HP:0002763) | 1.87737186 |
105 | Abnormality of iron homeostasis (HP:0011031) | 1.87532629 |
106 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.87331245 |
107 | Hypophosphatemic rickets (HP:0004912) | 1.85617191 |
108 | Abnormal enzyme/coenzyme activity (HP:0012379) | 1.84914308 |
109 | Hypothermia (HP:0002045) | 1.84794113 |
110 | Abnormality of carpal bone ossification (HP:0006257) | 1.84483941 |
111 | Flat acetabular roof (HP:0003180) | 1.83578388 |
112 | Elevated hepatic transaminases (HP:0002910) | 1.81978938 |
113 | Abnormality of vitamin metabolism (HP:0100508) | 1.80831748 |
114 | Glycosuria (HP:0003076) | 1.80476795 |
115 | Abnormality of urine glucose concentration (HP:0011016) | 1.80476795 |
116 | Nephritis (HP:0000123) | 1.79911922 |
117 | Generalized hypopigmentation of hair (HP:0011358) | 1.78920616 |
118 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.77835293 |
119 | Abnormality of the nasal septum (HP:0000419) | 1.71250041 |
120 | Hyperphosphaturia (HP:0003109) | 1.68117097 |
121 | Ileus (HP:0002595) | 1.59830381 |
122 | Cerebral palsy (HP:0100021) | 1.55501287 |
123 | Gangrene (HP:0100758) | 1.52872023 |
124 | Neoplasm of the liver (HP:0002896) | 1.52813144 |
125 | Increased mean platelet volume (HP:0011877) | 1.50630631 |
126 | Increased serum ferritin (HP:0003281) | 1.49713612 |
127 | Prolonged bleeding time (HP:0003010) | 1.49522269 |
128 | Broad alveolar ridges (HP:0000187) | 1.49212770 |
129 | Bifid scrotum (HP:0000048) | 1.48707403 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BCKDK | 6.80585365 |
2 | ERN1 | 4.49795568 |
3 | FGFR4 | 4.39136214 |
4 | SIK1 | 4.24632486 |
5 | ACVR1B | 4.10702753 |
6 | INSRR | 3.03510187 |
7 | TAOK3 | 3.03267760 |
8 | ERBB4 | 2.88320516 |
9 | MST1R | 2.67846985 |
10 | WNK4 | 2.59585850 |
11 | PDK2 | 2.22196814 |
12 | MAP2K4 | 2.18513776 |
13 | PIK3CG | 1.91439815 |
14 | MAPK11 | 1.86749480 |
15 | STK39 | 1.86590453 |
16 | PKN2 | 1.81516044 |
17 | FRK | 1.78658525 |
18 | FLT3 | 1.73659218 |
19 | FER | 1.69426095 |
20 | TYK2 | 1.65275552 |
21 | LATS1 | 1.58666755 |
22 | BMPR1B | 1.54826201 |
23 | OXSR1 | 1.54459226 |
24 | PTK6 | 1.53534200 |
25 | TRIB3 | 1.43806326 |
26 | MAPKAPK3 | 1.38693768 |
27 | NEK9 | 1.38273088 |
28 | ABL2 | 1.37985244 |
29 | NLK | 1.35019901 |
30 | FGFR2 | 1.28769740 |
31 | GRK6 | 1.27160631 |
32 | MAP3K7 | 1.26678431 |
33 | DAPK2 | 1.24897023 |
34 | PRKAA2 | 1.24057494 |
35 | KDR | 1.21071665 |
36 | JAK2 | 1.19984218 |
37 | MAP2K3 | 1.18362836 |
38 | LMTK2 | 1.15579941 |
39 | MAP3K14 | 1.13299701 |
40 | BCR | 1.12307907 |
41 | TBK1 | 1.12179223 |
42 | FGFR1 | 1.08823529 |
43 | EPHB1 | 1.05599018 |
44 | PINK1 | 1.05318781 |
45 | MAP3K3 | 1.05132973 |
46 | MAPK4 | 1.04137200 |
47 | ERBB2 | 1.00382871 |
48 | JAK1 | 0.99835335 |
49 | TIE1 | 0.98635500 |
50 | ADRBK2 | 0.97323544 |
51 | MAPK15 | 0.95162271 |
52 | MET | 0.94635077 |
53 | IRAK3 | 0.93592776 |
54 | MAP4K2 | 0.89124144 |
55 | WNK3 | 0.87386498 |
56 | MAP3K10 | 0.86340254 |
57 | PRKCZ | 0.86178059 |
58 | EIF2AK3 | 0.84167280 |
59 | STK38L | 0.82402500 |
60 | CSK | 0.82271514 |
61 | EPHA3 | 0.81748363 |
62 | ICK | 0.81256207 |
63 | MAPK12 | 0.80640863 |
64 | MYLK | 0.79991054 |
65 | MAP2K6 | 0.79887653 |
66 | CAMK2G | 0.79594159 |
67 | MAP3K11 | 0.79530294 |
68 | BRSK2 | 0.78640588 |
69 | NTRK3 | 0.78281248 |
70 | CAMK1D | 0.77609203 |
71 | CAMKK2 | 0.76948503 |
72 | TGFBR2 | 0.76842295 |
73 | MATK | 0.75370382 |
74 | PRKG2 | 0.74673123 |
75 | PRKACG | 0.74249098 |
76 | GRK1 | 0.73232595 |
77 | TYRO3 | 0.71807337 |
78 | GSK3A | 0.71374087 |
79 | SGK3 | 0.70598367 |
80 | CASK | 0.70276646 |
81 | CDK6 | 0.69910730 |
82 | STK38 | 0.68895968 |
83 | WNK1 | 0.68379103 |
84 | IKBKE | 0.68363540 |
85 | TNK2 | 0.66313749 |
86 | MAP3K12 | 0.64775336 |
87 | DYRK1B | 0.63774691 |
88 | RPS6KB1 | 0.63540823 |
89 | PAK3 | 0.63481138 |
90 | PRKAA1 | 0.62930926 |
91 | RIPK1 | 0.62886480 |
92 | PRKG1 | 0.60472214 |
93 | FGFR3 | 0.59116619 |
94 | FGR | 0.57800996 |
95 | EPHA2 | 0.57723570 |
96 | CSF1R | 0.57691585 |
97 | MAPK7 | 0.56834485 |
98 | PTK2 | 0.55872578 |
99 | SGK1 | 0.55831099 |
100 | SGK2 | 0.54385574 |
101 | PRKCQ | 0.53025002 |
102 | PDPK1 | 0.52687204 |
103 | MST4 | 0.51903942 |
104 | PRKCE | 0.50180083 |
105 | PRKACA | 0.48730544 |
106 | CSNK1D | 0.47802436 |
107 | PIK3CA | 0.47705111 |
108 | IGF1R | 0.46796120 |
109 | TAOK2 | 0.45244879 |
110 | MAP3K5 | 0.43977530 |
111 | MAP2K1 | 0.43768657 |
112 | TEC | 0.43364440 |
113 | PKN1 | 0.43105645 |
114 | CSNK1G1 | 0.41127997 |
115 | TXK | 0.41006945 |
116 | MAP3K13 | 0.40128929 |
117 | SRC | 0.40005200 |
118 | CSNK1E | 0.39272015 |
119 | PRKACB | 0.37929527 |
120 | SGK494 | 0.37791482 |
121 | SGK223 | 0.37791482 |
122 | PRKCB | 0.37184591 |
123 | MELK | 0.36731035 |
124 | MAP3K1 | 0.36720801 |
125 | PDGFRA | 0.36211196 |
126 | MAP2K2 | 0.36195743 |
127 | STK3 | 0.35021748 |
128 | IRAK1 | 0.34068688 |
129 | RET | 0.33939837 |
130 | NUAK1 | 0.32954548 |
131 | CAMK4 | 0.32146431 |
132 | EGFR | 0.31199009 |
133 | MAP3K6 | 0.30691870 |
134 | PDK1 | 0.30465545 |
135 | PRKCG | 0.27911249 |
136 | PRKCA | 0.27345478 |
137 | CAMK1G | 0.27180719 |
138 | IRAK2 | 0.26744131 |
139 | MAP3K2 | 0.26610911 |
140 | ABL1 | 0.26500764 |
141 | PBK | 0.25827590 |
142 | ITK | 0.25335105 |
143 | EPHB2 | 0.25245268 |
144 | CDK4 | 0.25125431 |
145 | AKT3 | 0.24566442 |
146 | MTOR | 0.23859154 |
147 | EPHA4 | 0.23641981 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 4.45634117 |
2 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.49445900 |
3 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 3.35113328 |
4 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 3.34095264 |
5 | Arginine biosynthesis_Homo sapiens_hsa00220 | 3.04063943 |
6 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.71986221 |
7 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 2.70648747 |
8 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.63316833 |
9 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.53894482 |
10 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.49250706 |
11 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.47568036 |
12 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.38030709 |
13 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.31578656 |
14 | * Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 2.11604245 |
15 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.11341403 |
16 | Peroxisome_Homo sapiens_hsa04146 | 2.07358679 |
17 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.98581746 |
18 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.97474182 |
19 | Histidine metabolism_Homo sapiens_hsa00340 | 1.97279999 |
20 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.93729191 |
21 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.91381654 |
22 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.91357227 |
23 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.89171423 |
24 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.78643329 |
25 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.74079746 |
26 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.73421706 |
27 | Retinol metabolism_Homo sapiens_hsa00830 | 1.73360581 |
28 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.72174144 |
29 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.66330988 |
30 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.65439330 |
31 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.58195861 |
32 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.55360799 |
33 | Bile secretion_Homo sapiens_hsa04976 | 1.51849130 |
34 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.50650580 |
35 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.50527660 |
36 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.43668389 |
37 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.43234142 |
38 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.41083442 |
39 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.37395620 |
40 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.36465703 |
41 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.32514578 |
42 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.29724212 |
43 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.27435102 |
44 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.24551542 |
45 | ABC transporters_Homo sapiens_hsa02010 | 1.23408717 |
46 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.15840165 |
47 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.12347592 |
48 | Carbon metabolism_Homo sapiens_hsa01200 | 1.10270414 |
49 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.08599517 |
50 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.05531688 |
51 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.01632864 |
52 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.99290355 |
53 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.96778776 |
54 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.95491941 |
55 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.92155813 |
56 | Sulfur relay system_Homo sapiens_hsa04122 | 0.91186346 |
57 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.91060342 |
58 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.87312247 |
59 | Lysine degradation_Homo sapiens_hsa00310 | 0.79415630 |
60 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.75091224 |
61 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.72206316 |
62 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.70924501 |
63 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.63457975 |
64 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.59248328 |
65 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.55238528 |
66 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.53223218 |
67 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.49053349 |
68 | Metabolic pathways_Homo sapiens_hsa01100 | 0.46068678 |
69 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.37504056 |
70 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.36881998 |
71 | Prion diseases_Homo sapiens_hsa05020 | 0.35789390 |
72 | Other glycan degradation_Homo sapiens_hsa00511 | 0.33512634 |
73 | Galactose metabolism_Homo sapiens_hsa00052 | 0.32454209 |
74 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.29672033 |
75 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.28326578 |
76 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.25500456 |
77 | Insulin resistance_Homo sapiens_hsa04931 | 0.23525384 |
78 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.22102175 |
79 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.17858805 |
80 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.17306297 |
81 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.13234268 |
82 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.09426087 |
83 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.08206595 |
84 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.01574377 |
85 | Circadian rhythm_Homo sapiens_hsa04710 | 0.00145443 |
86 | Pertussis_Homo sapiens_hsa05133 | -0.2246194 |
87 | Protein digestion and absorption_Homo sapiens_hsa04974 | -0.2178374 |
88 | Amoebiasis_Homo sapiens_hsa05146 | -0.2175188 |
89 | Ether lipid metabolism_Homo sapiens_hsa00565 | -0.2104155 |
90 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | -0.2029393 |
91 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | -0.1845992 |
92 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | -0.1783560 |
93 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | -0.1748796 |
94 | Mineral absorption_Homo sapiens_hsa04978 | -0.1671229 |
95 | Hepatitis C_Homo sapiens_hsa05160 | -0.1487970 |
96 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | -0.1443666 |
97 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | -0.1351935 |
98 | Regulation of autophagy_Homo sapiens_hsa04140 | -0.1318544 |
99 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | -0.1219494 |
100 | Pancreatic secretion_Homo sapiens_hsa04972 | -0.1207120 |
101 | Lysosome_Homo sapiens_hsa04142 | -0.1179843 |
102 | African trypanosomiasis_Homo sapiens_hsa05143 | -0.1172239 |
103 | Insulin signaling pathway_Homo sapiens_hsa04910 | -0.1115297 |
104 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | -0.0848143 |
105 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | -0.0661454 |
106 | Renin-angiotensin system_Homo sapiens_hsa04614 | -0.0543429 |
107 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | -0.0398984 |
108 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | -0.0376982 |
109 | Platelet activation_Homo sapiens_hsa04611 | -0.0328896 |
110 | Serotonergic synapse_Homo sapiens_hsa04726 | -0.0135346 |