FMR1NB

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit biogenesis (GO:0042274)5.35239566
2ribosome assembly (GO:0042255)5.26825019
3purine nucleobase biosynthetic process (GO:0009113)5.22898875
4chaperone-mediated protein transport (GO:0072321)5.03514990
5nucleobase biosynthetic process (GO:0046112)4.99799514
6mitotic metaphase plate congression (GO:0007080)4.92663503
7ribosome biogenesis (GO:0042254)4.60140970
8transcription from mitochondrial promoter (GO:0006390)4.58173387
9proteasome assembly (GO:0043248)4.57338308
10male meiosis I (GO:0007141)4.54801790
11DNA replication checkpoint (GO:0000076)4.50107631
12viral transcription (GO:0019083)4.34667894
13formation of translation preinitiation complex (GO:0001731)4.31889000
14translational termination (GO:0006415)4.30197653
15rRNA modification (GO:0000154)4.27715345
16synapsis (GO:0007129)4.26128454
17folic acid metabolic process (GO:0046655)4.17016960
18DNA deamination (GO:0045006)4.04908394
19meiosis I (GO:0007127)4.01959053
20metaphase plate congression (GO:0051310)4.01349227
21male meiosis (GO:0007140)3.99861803
22DNA replication initiation (GO:0006270)3.93241195
23ribonucleoprotein complex biogenesis (GO:0022613)3.90490119
24piRNA metabolic process (GO:0034587)3.89585600
25SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.88733026
26anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.86560105
27mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.86134810
28translational initiation (GO:0006413)3.83824029
29cotranslational protein targeting to membrane (GO:0006613)3.83305109
30DNA replication-dependent nucleosome assembly (GO:0006335)3.82337387
31DNA replication-dependent nucleosome organization (GO:0034723)3.82337387
32maturation of SSU-rRNA (GO:0030490)3.78922864
33protein localization to kinetochore (GO:0034501)3.78450882
34protein targeting to ER (GO:0045047)3.77855670
35CENP-A containing nucleosome assembly (GO:0034080)3.76754545
36DNA strand elongation involved in DNA replication (GO:0006271)3.74884259
37translational elongation (GO:0006414)3.74319958
38regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.74229650
39positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.72659751
40negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.72617836
41chromatin remodeling at centromere (GO:0031055)3.71949126
42regulation of oxidative phosphorylation (GO:0002082)3.67375305
43establishment of protein localization to endoplasmic reticulum (GO:0072599)3.61757364
44mitotic nuclear envelope disassembly (GO:0007077)3.61557222
45nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.60121677
46protein localization to endoplasmic reticulum (GO:0070972)3.59267393
47regulation of spindle organization (GO:0090224)3.58740723
48positive regulation of protein homooligomerization (GO:0032464)3.57256978
49kinetochore assembly (GO:0051382)3.57180481
50regulation of translation in response to stress (GO:0043555)3.56567374
51translation (GO:0006412)3.55875095
52regulation of nuclear cell cycle DNA replication (GO:0033262)3.55855351
53DNA strand elongation (GO:0022616)3.54689269
54termination of RNA polymerase III transcription (GO:0006386)3.50652665
55transcription elongation from RNA polymerase III promoter (GO:0006385)3.50652665
56telomere maintenance via semi-conservative replication (GO:0032201)3.50311376
57establishment of chromosome localization (GO:0051303)3.49799169
58rRNA processing (GO:0006364)3.49623017
59mitochondrial RNA metabolic process (GO:0000959)3.48685600
60cellular component biogenesis (GO:0044085)3.48244980
61transcription from RNA polymerase I promoter (GO:0006360)3.48188639
62ribosomal large subunit biogenesis (GO:0042273)3.47287591
63viral life cycle (GO:0019058)3.45969862
64DNA replication-independent nucleosome assembly (GO:0006336)3.45574675
65DNA replication-independent nucleosome organization (GO:0034724)3.45574675
667-methylguanosine mRNA capping (GO:0006370)3.45235721
67kinetochore organization (GO:0051383)3.45227863
68positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.43639664
69protein K6-linked ubiquitination (GO:0085020)3.43408488
70mitotic sister chromatid segregation (GO:0000070)3.42800323
71histone exchange (GO:0043486)3.42262332
72spliceosomal snRNP assembly (GO:0000387)3.42086713
73regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.41386430
74attachment of spindle microtubules to kinetochore (GO:0008608)3.39592243
75rRNA metabolic process (GO:0016072)3.38764053
76negative regulation of ligase activity (GO:0051352)3.37286582
77negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.37286582
78maturation of 5.8S rRNA (GO:0000460)3.36442366
79protein localization to chromosome, centromeric region (GO:0071459)3.36365254
807-methylguanosine RNA capping (GO:0009452)3.35507623
81RNA capping (GO:0036260)3.35507623
82spindle checkpoint (GO:0031577)3.35266182
83termination of RNA polymerase I transcription (GO:0006363)3.34848834
84mitotic chromosome condensation (GO:0007076)3.34823827
85negative regulation of chromosome segregation (GO:0051985)3.34642555
86membrane disassembly (GO:0030397)3.33925308
87nuclear envelope disassembly (GO:0051081)3.33925308
88transcription elongation from RNA polymerase I promoter (GO:0006362)3.32129002
89phenylpropanoid metabolic process (GO:0009698)3.29698814
90ribosomal small subunit assembly (GO:0000028)3.29188309
91cellular protein complex disassembly (GO:0043624)3.29065368
92energy coupled proton transport, down electrochemical gradient (GO:0015985)3.28563154
93ATP synthesis coupled proton transport (GO:0015986)3.28563154
94protein targeting to mitochondrion (GO:0006626)3.28387285
95negative regulation of mitotic sister chromatid separation (GO:2000816)3.28115018
96negative regulation of mitotic sister chromatid segregation (GO:0033048)3.28115018
97negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.28115018
98negative regulation of sister chromatid segregation (GO:0033046)3.28115018
99nuclear pore organization (GO:0006999)3.28008781
100blastocyst development (GO:0001824)3.24826547
101positive regulation of chromosome segregation (GO:0051984)3.24558387
102regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.23567620
103negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.23475610
104transcription-coupled nucleotide-excision repair (GO:0006283)3.22904732
105telomere maintenance via recombination (GO:0000722)3.22108765
106mitotic spindle assembly checkpoint (GO:0007094)3.21693140
107positive regulation of ligase activity (GO:0051351)3.21287791
108folic acid transport (GO:0015884)3.20988743
109DNA methylation involved in gamete generation (GO:0043046)3.20947625
110regulation of double-strand break repair via homologous recombination (GO:0010569)3.20373548
111regulation of cellular respiration (GO:0043457)3.20141792
112pseudouridine synthesis (GO:0001522)3.19729853
113spindle assembly checkpoint (GO:0071173)3.19309021
114mitotic spindle checkpoint (GO:0071174)3.18722247
115signal transduction involved in DNA damage checkpoint (GO:0072422)3.18134600
116signal transduction involved in DNA integrity checkpoint (GO:0072401)3.18134600
117flavonoid metabolic process (GO:0009812)3.14905919
118rRNA methylation (GO:0031167)3.14762321
119IMP biosynthetic process (GO:0006188)3.14531673
120regulation of cellular amino acid metabolic process (GO:0006521)3.13811820
121signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.13800485
122signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.13800485
123signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.13800485
124regulation of chromosome segregation (GO:0051983)3.13178980
125DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.12557379
126signal transduction involved in cell cycle checkpoint (GO:0072395)3.12460923
127regulation of mitotic metaphase/anaphase transition (GO:0030071)3.12125967
128regulation of centrosome cycle (GO:0046605)3.11162446
129regulation of gene silencing by RNA (GO:0060966)3.10556245
130regulation of posttranscriptional gene silencing (GO:0060147)3.10556245
131regulation of gene silencing by miRNA (GO:0060964)3.10556245
132G1/S transition of mitotic cell cycle (GO:0000082)3.09859808
133cell cycle G1/S phase transition (GO:0044843)3.09859808
134regulation of ubiquitin-protein transferase activity (GO:0051438)3.09367265
135regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.08904358
136mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.07646395
137chromosome organization involved in meiosis (GO:0070192)2.97156335
138regulation of mitochondrial translation (GO:0070129)2.96076451
139regulation of ligase activity (GO:0051340)2.95942070
140telomere maintenance via telomere lengthening (GO:0010833)2.93474895
141sister chromatid segregation (GO:0000819)2.92635264
142meiotic nuclear division (GO:0007126)2.91557705
143exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.90465154
144mitotic recombination (GO:0006312)2.88730691
145respiratory electron transport chain (GO:0022904)2.88578750
146regulation of DNA methylation (GO:0044030)2.88150988
147nuclear-transcribed mRNA catabolic process (GO:0000956)2.84720381
148electron transport chain (GO:0022900)2.84116380
149establishment of protein localization to mitochondrion (GO:0072655)2.83747103
150gonadal mesoderm development (GO:0007506)13.3773849
151negative regulation of retinoic acid receptor signaling pathway (GO:0048387)11.9309488
152regulation of retinoic acid receptor signaling pathway (GO:0048385)10.5193655

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.17352997
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.17460511
3E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.54438315
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.48674164
5FOXM1_23109430_ChIP-Seq_U2OS_Human3.43672153
6JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.20187054
7MYC_19079543_ChIP-ChIP_MESCs_Mouse3.19649270
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.16847555
9EST1_17652178_ChIP-ChIP_JURKAT_Human3.16345594
10E2F4_17652178_ChIP-ChIP_JURKAT_Human3.11516682
11EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.08306572
12GABP_17652178_ChIP-ChIP_JURKAT_Human3.01429118
13CREB1_15753290_ChIP-ChIP_HEK293T_Human2.97817410
14MYC_19030024_ChIP-ChIP_MESCs_Mouse2.91088826
15MYC_18358816_ChIP-ChIP_MESCs_Mouse2.87340550
16FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.77814099
17MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.62474078
18RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.51490174
19NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.44512869
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.42117578
21NELFA_20434984_ChIP-Seq_ESCs_Mouse2.35997881
22NANOG_18555785_ChIP-Seq_MESCs_Mouse2.33351965
23SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.31880575
24POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.20295764
25VDR_23849224_ChIP-Seq_CD4+_Human2.19001595
26AR_21909140_ChIP-Seq_LNCAP_Human2.17051687
27XRN2_22483619_ChIP-Seq_HELA_Human2.16095617
28E2F1_18555785_ChIP-Seq_MESCs_Mouse2.15010296
29POU5F1_18555785_ChIP-Seq_MESCs_Mouse2.12923674
30HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.10443897
31KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.10324278
32KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.10324278
33KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.10324278
34MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.04857003
35SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.02264964
36NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.97007141
37MYCN_18555785_ChIP-Seq_MESCs_Mouse1.95245070
38YY1_21170310_ChIP-Seq_MESCs_Mouse1.93074939
39HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.87255415
40DCP1A_22483619_ChIP-Seq_HELA_Human1.85864536
41GABP_19822575_ChIP-Seq_HepG2_Human1.85826575
42KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.84050938
43THAP11_20581084_ChIP-Seq_MESCs_Mouse1.80650263
44NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.76761695
45FOXP3_21729870_ChIP-Seq_TREG_Human1.75748718
46STAT3_1855785_ChIP-Seq_MESCs_Mouse1.74373502
47POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.67740439
48TTF2_22483619_ChIP-Seq_HELA_Human1.66259578
49PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.60594776
50TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.57452355
51YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.57058836
52ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.54879941
53TCF3_18692474_ChIP-Seq_MEFs_Mouse1.51044654
54E2F1_21310950_ChIP-Seq_MCF-7_Human1.50178745
55CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.48246337
56KDM5A_27292631_Chip-Seq_BREAST_Human1.45202536
57ELF1_17652178_ChIP-ChIP_JURKAT_Human1.38743532
58CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.37318759
59KLF4_18555785_ChIP-Seq_MESCs_Mouse1.37079955
60SALL1_21062744_ChIP-ChIP_HESCs_Human1.36932224
61NOTCH1_21737748_ChIP-Seq_TLL_Human1.36901414
62KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.36378545
63ELK1_19687146_ChIP-ChIP_HELA_Human1.35773812
64NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.35571578
65MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.34234379
66SRF_21415370_ChIP-Seq_HL-1_Mouse1.33717011
67ZNF274_21170338_ChIP-Seq_K562_Hela1.33149098
68ZFX_18555785_ChIP-Seq_MESCs_Mouse1.33011159
69TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.32967385
70SOX2_18555785_ChIP-Seq_MESCs_Mouse1.29660998
71FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.25401740
72TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.24897943
73IRF1_19129219_ChIP-ChIP_H3396_Human1.23615976
74NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.22211136
75SOX2_18692474_ChIP-Seq_MEFs_Mouse1.21575240
76TCF3_18692474_ChIP-Seq_MESCs_Mouse1.20428677
77ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.19838363
78PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.19330668
79CIITA_25753668_ChIP-Seq_RAJI_Human1.17960206
80NANOG_21062744_ChIP-ChIP_HESCs_Human1.16472673
81KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.16054674
82SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.15928403
83ERG_20887958_ChIP-Seq_HPC-7_Mouse1.15756963
84ESR1_15608294_ChIP-ChIP_MCF-7_Human1.15523050
85ZNF263_19887448_ChIP-Seq_K562_Human1.14795874
86OCT4_18692474_ChIP-Seq_MEFs_Mouse1.14218070
87PADI4_21655091_ChIP-ChIP_MCF-7_Human1.13030810
88TP63_19390658_ChIP-ChIP_HaCaT_Human1.12281812
89BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.11029963
90FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.10834708
91CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.10755345
92DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.07907265
93NANOG_18692474_ChIP-Seq_MEFs_Mouse1.07205529
94SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.05955123
95ELK1_22589737_ChIP-Seq_MCF10A_Human1.05739746
96CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.05332074
97CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.04287018
98POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.03119589
99HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.01370130
100SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.00882371
101SOX2_18692474_ChIP-Seq_MESCs_Mouse0.99379710
102HOXB4_20404135_ChIP-ChIP_EML_Mouse0.98552146
103TFEB_21752829_ChIP-Seq_HELA_Human0.98362076
104SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.96380682
105ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.96102727
106HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.95943035
107CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.94562077
108E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.93120664
109CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.92635915
110MYC_18940864_ChIP-ChIP_HL60_Human0.91834493
111NANOG_18692474_ChIP-Seq_MESCs_Mouse0.88633205
112KAP1_27257070_Chip-Seq_ESCs_Mouse0.88008112
113EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.87784268
114NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.87531392
115GATA1_26923725_Chip-Seq_HPCs_Mouse0.87473710
116ELF5_23300383_ChIP-Seq_T47D_Human0.86576844
117CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.86383845
118POU5F1_16518401_ChIP-PET_MESCs_Mouse0.86216128
119TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.85234733
120SOX17_20123909_ChIP-Seq_XEN_Mouse0.85131262
121RBPJ_21746931_ChIP-Seq_IB4_Human0.80216764
122LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.80215024
123TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.79096031
124ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.76865113
125HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.75558240
126FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.71948935
127SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.71825164
128CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.69796979

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching6.42283196
2MP0003111_abnormal_nucleus_morphology4.94878124
3MP0004957_abnormal_blastocyst_morpholog4.82005061
4MP0010094_abnormal_chromosome_stability4.15078139
5MP0003077_abnormal_cell_cycle3.90623423
6MP0002638_abnormal_pupillary_reflex3.87659815
7MP0003718_maternal_effect3.61553061
8MP0002254_reproductive_system_inflammat3.60943223
9MP0008057_abnormal_DNA_replication3.50618581
10MP0008058_abnormal_DNA_repair3.30722236
11MP0001986_abnormal_taste_sensitivity2.92691792
12MP0008932_abnormal_embryonic_tissue2.86129743
13MP0008877_abnormal_DNA_methylation2.75790085
14MP0003123_paternal_imprinting2.64072352
15MP0001730_embryonic_growth_arrest2.59960699
16MP0003786_premature_aging2.59271604
17MP0003806_abnormal_nucleotide_metabolis2.48777348
18MP0008007_abnormal_cellular_replicative2.37553100
19MP0009697_abnormal_copulation2.32760744
20MP0000350_abnormal_cell_proliferation2.13158469
21MP0005380_embryogenesis_phenotype2.05236167
22MP0001672_abnormal_embryogenesis/_devel2.05236167
23MP0001346_abnormal_lacrimal_gland2.00811253
24MP0009379_abnormal_foot_pigmentation1.91642465
25MP0003315_abnormal_perineum_morphology1.90279215
26MP0001697_abnormal_embryo_size1.82555310
27MP0005423_abnormal_somatic_nervous1.81838742
28MP0002138_abnormal_hepatobiliary_system1.78588073
29MP0002938_white_spotting1.76413565
30MP0003984_embryonic_growth_retardation1.74638358
31MP0002088_abnormal_embryonic_growth/wei1.72722153
32MP0005410_abnormal_fertilization1.68335818
33MP0010352_gastrointestinal_tract_polyps1.67791346
34MP0001348_abnormal_lacrimal_gland1.67266721
35MP0003941_abnormal_skin_development1.66978934
36MP0002085_abnormal_embryonic_tissue1.66411013
37MP0002210_abnormal_sex_determination1.65051386
38MP0002876_abnormal_thyroid_physiology1.63478508
39MP0002080_prenatal_lethality1.62953152
40MP0000647_abnormal_sebaceous_gland1.60897294
41MP0008260_abnormal_autophagy1.58989730
42MP0002084_abnormal_developmental_patter1.55445113
43MP0002653_abnormal_ependyma_morphology1.54859191
44MP0009840_abnormal_foam_cell1.53669369
45MP0002086_abnormal_extraembryonic_tissu1.52776313
46MP0001145_abnormal_male_reproductive1.50725479
47MP0008872_abnormal_physiological_respon1.45466045
48MP0005395_other_phenotype1.44273947
49MP0001929_abnormal_gametogenesis1.40679566
50MP0003119_abnormal_digestive_system1.37027739
51MP0004133_heterotaxia1.35846479
52MP0010307_abnormal_tumor_latency1.32600674
53MP0006292_abnormal_olfactory_placode1.31409057
54MP0004197_abnormal_fetal_growth/weight/1.31285070
55MP0004264_abnormal_extraembryonic_tissu1.30699943
56MP0000653_abnormal_sex_gland1.30688174
57MP0006035_abnormal_mitochondrial_morpho1.29313827
58MP0003567_abnormal_fetal_cardiomyocyte1.28483249
59MP0000313_abnormal_cell_death1.27501419
60MP0008875_abnormal_xenobiotic_pharmacok1.25195109
61MP0003890_abnormal_embryonic-extraembry1.24562059
62MP0003186_abnormal_redox_activity1.21297508
63MP0003950_abnormal_plasma_membrane1.12549251
64MP0005451_abnormal_body_composition1.12259500
65MP0004381_abnormal_hair_follicle1.11400576
66MP0000358_abnormal_cell_content/1.10625835
67MP0005058_abnormal_lysosome_morphology1.10450317
68MP0003878_abnormal_ear_physiology1.10194905
69MP0005377_hearing/vestibular/ear_phenot1.10194905
70MP0005389_reproductive_system_phenotype1.09677830
71MP0002396_abnormal_hematopoietic_system1.03512344
72MP0002019_abnormal_tumor_incidence1.03059292
73MP0001293_anophthalmia1.01970309
74MP0002160_abnormal_reproductive_system1.01567655
75MP0001661_extended_life_span1.00358209
76MP0005636_abnormal_mineral_homeostasis1.00172117
77MP0005647_abnormal_sex_gland0.99825945
78MP0001119_abnormal_female_reproductive0.93508526
79MP0005646_abnormal_pituitary_gland0.93494863
80MP0003221_abnormal_cardiomyocyte_apopto0.93180678
81MP0005384_cellular_phenotype0.92418342
82MP0000750_abnormal_muscle_regeneration0.91353176
83MP0010030_abnormal_orbit_morphology0.90575110
84MP0004019_abnormal_vitamin_homeostasis0.90124445
85MP0001853_heart_inflammation0.89275282
86MP0001919_abnormal_reproductive_system0.89134452
87MP0000490_abnormal_crypts_of0.88722661
88MP0003121_genomic_imprinting0.87413785
89MP0005670_abnormal_white_adipose0.87018685
90MP0003938_abnormal_ear_development0.86865329
91MP0005621_abnormal_cell_physiology0.86282474
92MP0003698_abnormal_male_reproductive0.85668496
93MP0006036_abnormal_mitochondrial_physio0.85519294
94MP0009672_abnormal_birth_weight0.84486867
95MP0003936_abnormal_reproductive_system0.84269564
96MP0001764_abnormal_homeostasis0.83759923
97MP0003699_abnormal_female_reproductive0.83576033
98MP0004084_abnormal_cardiac_muscle0.83570732
99MP0003646_muscle_fatigue0.82845623
100MP0003937_abnormal_limbs/digits/tail_de0.82215254
101MP0002111_abnormal_tail_morphology0.82198483
102MP0009333_abnormal_splenocyte_physiolog0.80726397
103MP0005408_hypopigmentation0.80638821
104MP0001873_stomach_inflammation0.80541703
105MP0005266_abnormal_metabolism0.79920943
106MP0002161_abnormal_fertility/fecundity0.79035783
107MP0000427_abnormal_hair_cycle0.77654149
108MP0002269_muscular_atrophy0.77553095
109MP0000678_abnormal_parathyroid_gland0.76972042
110MP0003136_yellow_coat_color0.76515693
111MP0005075_abnormal_melanosome_morpholog0.76322924
112MP0005367_renal/urinary_system_phenotyp0.76059123
113MP0000516_abnormal_urinary_system0.76059123
114MP0001727_abnormal_embryo_implantation0.73691364
115MP0001542_abnormal_bone_strength0.73422352
116MP0004215_abnormal_myocardial_fiber0.72306997
117MP0009703_decreased_birth_body0.70576047
118MP0008995_early_reproductive_senescence0.70508399
119MP0000627_abnormal_mammary_gland0.70490915
120MP0002796_impaired_skin_barrier0.68199197
121MP0001849_ear_inflammation0.67631619
122MP0001905_abnormal_dopamine_level0.67052797
123MP0005076_abnormal_cell_differentiation0.66585026
124MP0000639_abnormal_adrenal_gland0.65407828
125MP0005360_urolithiasis0.63314049
126MP0005330_cardiomyopathy0.62826257
127MP0000428_abnormal_craniofacial_morphol0.61719023
128MP0000372_irregular_coat_pigmentation0.61486797
129MP0000015_abnormal_ear_pigmentation0.61058941
130MP0002095_abnormal_skin_pigmentation0.60137122
131MP0005023_abnormal_wound_healing0.59704913
132MP0002092_abnormal_eye_morphology0.59561020
133MP0001286_abnormal_eye_development0.59140930
134MP0001756_abnormal_urination0.58931687
135MP0000613_abnormal_salivary_gland0.58863287
136MP0004782_abnormal_surfactant_physiolog0.58472665
137MP0000537_abnormal_urethra_morphology0.58261412
138MP0003943_abnormal_hepatobiliary_system0.57703532
139MP0005501_abnormal_skin_physiology0.57218179
140MP0001502_abnormal_circadian_rhythm0.55961723
141MP0001765_abnormal_ion_homeostasis0.55130107
142MP0005332_abnormal_amino_acid0.54813705

Predicted human phenotypes

RankGene SetZ-score
1Breast hypoplasia (HP:0003187)5.74577343
2Birth length less than 3rd percentile (HP:0003561)5.37214633
3Carpal bone hypoplasia (HP:0001498)5.21170064
4Increased circulating renin level (HP:0000848)5.07247907
5Decreased activity of mitochondrial respiratory chain (HP:0008972)4.22627046
6Abnormal activity of mitochondrial respiratory chain (HP:0011922)4.22627046
7Paralysis (HP:0003470)4.22120609
8Cerebral hypomyelination (HP:0006808)4.21709888
9Absent radius (HP:0003974)3.97175781
10Aplasia/Hypoplasia involving the carpal bones (HP:0006502)3.96351217
11Abnormality of magnesium homeostasis (HP:0004921)3.95262440
12Rough bone trabeculation (HP:0100670)3.90238948
13Hypomagnesemia (HP:0002917)3.87185980
14Tetany (HP:0001281)3.85706535
15Impulsivity (HP:0100710)3.82374548
16Absent forearm bone (HP:0003953)3.73051835
17Aplasia involving forearm bones (HP:0009822)3.73051835
18Patellar aplasia (HP:0006443)3.67470360
19Aplasia/Hypoplasia of the patella (HP:0006498)3.56739771
20Hypokalemic alkalosis (HP:0001949)3.42787002
21Abnormality of the labia minora (HP:0012880)3.37617385
223-Methylglutaconic aciduria (HP:0003535)3.37545644
23Premature ovarian failure (HP:0008209)3.37354889
24Degeneration of anterior horn cells (HP:0002398)3.35879091
25Abnormality of the anterior horn cell (HP:0006802)3.35879091
26Oral leukoplakia (HP:0002745)3.33118559
27Aplasia/Hypoplasia involving the musculature (HP:0001460)3.24180857
28Multiple enchondromatosis (HP:0005701)3.20357370
29Aplasia/hypoplasia of the humerus (HP:0006507)3.20346430
30Ependymoma (HP:0002888)3.18511277
31Chromosomal breakage induced by crosslinking agents (HP:0003221)3.15366936
32Acute necrotizing encephalopathy (HP:0006965)3.13316378
33Aplasia/Hypoplasia of the sacrum (HP:0008517)3.11443318
34Meckel diverticulum (HP:0002245)3.11209324
35Secondary amenorrhea (HP:0000869)3.10207739
36Chromsome breakage (HP:0040012)3.04758490
37Male infertility (HP:0003251)3.02556740
38Renal Fanconi syndrome (HP:0001994)3.01121139
39Bilateral sensorineural hearing impairment (HP:0008619)2.97027229
40Patent foramen ovale (HP:0001655)2.96757876
41Abnormal number of erythroid precursors (HP:0012131)2.96702977
42Hyperglycinemia (HP:0002154)2.95873944
43Abnormality of the ileum (HP:0001549)2.94244546
44Abnormal mitochondria in muscle tissue (HP:0008316)2.93357508
45Ileus (HP:0002595)2.91557432
46Increased CSF lactate (HP:0002490)2.89332050
47Abnormal trabecular bone morphology (HP:0100671)2.87394604
48Renal tubular acidosis (HP:0001947)2.86421185
49Progressive muscle weakness (HP:0003323)2.85711105
50Ureteral duplication (HP:0000073)2.84106047
51Selective tooth agenesis (HP:0001592)2.81801081
52Hyperglycinuria (HP:0003108)2.72867069
53Acute encephalopathy (HP:0006846)2.69780881
54Horseshoe kidney (HP:0000085)2.69331408
55Supernumerary spleens (HP:0009799)2.67383594
56Absent thumb (HP:0009777)2.66437311
57Trismus (HP:0000211)2.65460850
58Abnormality of the preputium (HP:0100587)2.64846158
59Mitochondrial inheritance (HP:0001427)2.62419673
60Hypoparathyroidism (HP:0000829)2.61998091
61CNS hypomyelination (HP:0003429)2.60505114
62Fused cervical vertebrae (HP:0002949)2.56835103
63Stenosis of the external auditory canal (HP:0000402)2.56089288
64Polydipsia (HP:0001959)2.55661245
65Abnormal drinking behavior (HP:0030082)2.55661245
66Truncus arteriosus (HP:0001660)2.54302872
67Renal tubular dysfunction (HP:0000124)2.53431446
68Delayed CNS myelination (HP:0002188)2.52835855
69Pallor (HP:0000980)2.49119312
70Increased hepatocellular lipid droplets (HP:0006565)2.48881107
71Progressive macrocephaly (HP:0004481)2.48831148
72Abnormality of renin-angiotensin system (HP:0000847)2.48816581
73Type I transferrin isoform profile (HP:0003642)2.47098549
74Amelogenesis imperfecta (HP:0000705)2.46110424
75Testicular atrophy (HP:0000029)2.44656074
76Megaloblastic anemia (HP:0001889)2.43007376
77Increased serum lactate (HP:0002151)2.41988113
78Microretrognathia (HP:0000308)2.40939604
79Aplasia/Hypoplasia of the uvula (HP:0010293)2.39885501
80Proximal tubulopathy (HP:0000114)2.39189772
81Colon cancer (HP:0003003)2.38399139
82Rectal fistula (HP:0100590)2.37635507
83Rectovaginal fistula (HP:0000143)2.37635507
84Short humerus (HP:0005792)2.37281628
85Abnormality of chromosome stability (HP:0003220)2.36144278
86Bone marrow hypocellularity (HP:0005528)2.35264375
87Neoplasm of the pancreas (HP:0002894)2.32566170
88Rhabdomyosarcoma (HP:0002859)2.32190077
89Premature graying of hair (HP:0002216)2.32051799
90Spinal muscular atrophy (HP:0007269)2.30697571
91Personality changes (HP:0000751)2.29302161
92Sparse eyelashes (HP:0000653)2.29220523
93Medulloblastoma (HP:0002885)2.28313813
94Reticulocytopenia (HP:0001896)2.26616267
95Asplenia (HP:0001746)2.26467114
96Atrophy/Degeneration involving motor neurons (HP:0007373)2.24502787
97Generalized aminoaciduria (HP:0002909)2.23229986
98Abnormality of the renal collecting system (HP:0004742)2.23118728
99Increased serum pyruvate (HP:0003542)2.21361019
100Abnormal spermatogenesis (HP:0008669)2.20895468
101Macrocytic anemia (HP:0001972)2.17996262
102Abnormality of the umbilical cord (HP:0010881)2.17817762
103Aplasia/Hypoplasia of the spleen (HP:0010451)2.17797253
104Lactic acidosis (HP:0003128)2.17163554
105Azoospermia (HP:0000027)2.16355285
106Agnosia (HP:0010524)2.15849982
107Lipid accumulation in hepatocytes (HP:0006561)2.15758149
108Glioma (HP:0009733)2.13476514
109Small intestinal stenosis (HP:0012848)2.12994656
110Duodenal stenosis (HP:0100867)2.12994656
111Cellular immunodeficiency (HP:0005374)2.12297843
112Shawl scrotum (HP:0000049)2.11305932
113Abnormality of serine family amino acid metabolism (HP:0010894)2.11137317
114Abnormality of glycine metabolism (HP:0010895)2.11137317
115Progressive external ophthalmoplegia (HP:0000590)2.10577912
116Abnormality of glycolysis (HP:0004366)2.09819480
117Hypercortisolism (HP:0001578)2.09548279
118Death in infancy (HP:0001522)2.04940656
119Abnormal gallbladder physiology (HP:0012438)2.04703657
120Cholecystitis (HP:0001082)2.04703657
121Seborrheic dermatitis (HP:0001051)2.01204599
122Tongue fasciculations (HP:0001308)2.01091295
123Triphalangeal thumb (HP:0001199)1.99558588
124Tinnitus (HP:0000360)1.99545745
125External ophthalmoplegia (HP:0000544)1.99423524
126Posterior subcapsular cataract (HP:0007787)1.99223851
127Hypoplasia of the radius (HP:0002984)1.99100668
128Cleft eyelid (HP:0000625)1.98309783
129Abnormality of dental color (HP:0011073)1.97849979
130Breast aplasia (HP:0100783)1.97796230
131Hepatic necrosis (HP:0002605)1.96659950
132Tracheoesophageal fistula (HP:0002575)1.96543951
133Reduced antithrombin III activity (HP:0001976)1.94665650
134Vaginal fistula (HP:0004320)1.94413214
135Increased intramyocellular lipid droplets (HP:0012240)1.93845588
136Aplasia/Hypoplasia of the breasts (HP:0010311)1.92604741
137Abnormality of the fetal cardiovascular system (HP:0010948)1.92152401
138Abnormal umbilical cord blood vessels (HP:0011403)1.92152401
139Single umbilical artery (HP:0001195)1.92152401
140Hepatocellular necrosis (HP:0001404)1.91128351
141Intestinal fistula (HP:0100819)1.90741005
142Abnormality of the astrocytes (HP:0100707)1.90504047
143Astrocytoma (HP:0009592)1.90504047
144Hypokinesia (HP:0002375)1.89872280
145Abnormality of serum amino acid levels (HP:0003112)1.89198153
146Abnormality of cells of the erythroid lineage (HP:0012130)1.88881942
147Glycosuria (HP:0003076)1.88852344
148Abnormality of urine glucose concentration (HP:0011016)1.88852344
149Constricted visual fields (HP:0001133)1.88568206
150Muscle fibrillation (HP:0010546)1.87379583
151Methylmalonic acidemia (HP:0002912)1.86147627
152Neoplasm of the peripheral nervous system (HP:0100007)1.85587214
153Gout (HP:0001997)1.85340277
154Aplastic anemia (HP:0001915)1.84896091
155Anal stenosis (HP:0002025)1.83324418
156Facial hemangioma (HP:0000329)1.83167015
157Hypoplasia of the uterus (HP:0000013)1.82642460
158Duplicated collecting system (HP:0000081)1.82530207
159Areflexia of lower limbs (HP:0002522)1.81538870
160Short thumb (HP:0009778)1.81464998
161Myelodysplasia (HP:0002863)1.81261804
162Delusions (HP:0000746)1.81071102
163Abnormality of renal resorption (HP:0011038)1.79522012
164Abnormality of alanine metabolism (HP:0010916)1.79265368
165Hyperalaninemia (HP:0003348)1.79265368
166Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.79265368
167Aplasia/hypoplasia of the uterus (HP:0008684)1.78680684
168Abnormality of the duodenum (HP:0002246)1.76333297
169Exercise intolerance (HP:0003546)1.76122608
170Postnatal microcephaly (HP:0005484)1.75805232
171Abnormality of aromatic amino acid family metabolism (HP:0004338)1.75609023
172Polyuria (HP:0000103)1.73283087

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WNK47.07823216
2STK396.30913974
3BUB15.55537750
4OXSR14.93507732
5WEE14.75291131
6EPHA23.97569539
7PLK43.58000527
8EIF2AK13.23054784
9TTK2.93253991
10SRPK12.91047604
11NEK12.67851665
12CDC72.66529312
13NEK22.51095775
14AKT32.49608887
15STK162.37922259
16TSSK62.30430628
17PLK12.20994797
18PNCK2.19280775
19EIF2AK32.00920016
20BRSK21.89305231
21PLK31.75352017
22ACVR1B1.62953417
23ZAK1.62165821
24RPS6KB21.61050321
25CDK121.54775936
26CHEK21.51382530
27STK38L1.50329409
28TESK21.47714336
29PINK11.40482965
30AURKA1.39906337
31AURKB1.39331444
32CDK71.36602010
33PDK41.33560062
34PDK31.33560062
35DYRK31.32454996
36NME21.31439322
37IRAK31.21490577
38BRAF1.19956467
39LATS21.18959514
40BRSK11.17612406
41MAP3K81.13705140
42TNIK1.13113030
43VRK11.12434750
44ATR1.10591779
45CHEK11.05621147
46VRK21.03799861
47PDK21.03643806
48PRKCI1.02847800
49KSR21.00265181
50MKNK10.98623737
51PAK40.96679835
52MKNK20.94470526
53CDK40.93247230
54ARAF0.90360112
55ALK0.89205389
56NME10.85345525
57DYRK20.82929704
58TLK10.82035100
59MAP3K20.81849737
60EIF2AK20.79225273
61CDK20.78789900
62NUAK10.78331788
63TRIM280.78285589
64STK100.77767711
65PAK10.73379297
66MAP3K130.71483557
67PRKG20.70700570
68KSR10.69536992
69PBK0.68760797
70CDK80.67250901
71BCKDK0.65415325
72STK40.63780558
73BMPR1B0.62818674
74ATM0.62088429
75CSNK2A20.61799785
76CSNK2A10.61272652
77CSNK1E0.58637212
78PASK0.57854477
79CCNB10.57592435
80CDK10.56267078
81MAP3K110.55940700
82MELK0.55778742
83STK30.55769648
84MST1R0.55240072
85ABL20.55228296
86PIM20.54764888
87NEK60.51774480
88CLK10.50548180
89FLT30.49886901
90PIM10.49875445
91MAPKAPK30.48848837
92PKN10.47074994
93PLK20.46259747
94RPS6KA40.43492378
95MAP2K70.39318508
96MAP3K50.39025170
97TAOK30.38536329
98MTOR0.38469809
99BRD40.34938958
100BMX0.34174551
101CDK90.33915084
102KDR0.32786063
103MARK10.32066874
104ILK0.29972947
105RPS6KA50.28809146
106TAOK20.26461423
107MST40.26400417
108AKT20.25021978
109STK380.23326324
110MAP3K90.22926001
111CDK60.22558938
112MAP3K120.21290955
113LATS10.20943665
114MAP2K20.20390714
115ERBB40.19772667
116SCYL20.19715930
117PRKDC0.19447428
118MARK30.18667886
119CDK30.18279171
120WNK30.18035561
121STK240.17856388
122MET0.17612936
123PAK20.17589115
124MOS0.17039097
125GSK3B0.16014953
126CSNK1G10.15961712
127MAPK100.15879895
128MAPK140.15010795
129MAP2K10.14065293
130TESK10.13171880
131RAF10.12027674
132CSNK1A10.10514591
133PRKCD0.09433277
134NTRK30.09132251
135IKBKB0.09071026

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.49616996
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.47466302
3RNA polymerase_Homo sapiens_hsa030204.24365107
4DNA replication_Homo sapiens_hsa030303.94099741
5Mismatch repair_Homo sapiens_hsa034303.63024872
6RNA transport_Homo sapiens_hsa030133.49692132
7Spliceosome_Homo sapiens_hsa030403.07820031
8Ribosome_Homo sapiens_hsa030103.02070537
9Vitamin B6 metabolism_Homo sapiens_hsa007502.86187104
10Homologous recombination_Homo sapiens_hsa034402.68175818
11Pyrimidine metabolism_Homo sapiens_hsa002402.64074286
12Nucleotide excision repair_Homo sapiens_hsa034202.57057157
13Base excision repair_Homo sapiens_hsa034102.42768750
14Cell cycle_Homo sapiens_hsa041102.42208086
15Collecting duct acid secretion_Homo sapiens_hsa049662.39147300
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.32974901
17Basal transcription factors_Homo sapiens_hsa030222.28052950
18One carbon pool by folate_Homo sapiens_hsa006702.23570691
19Fanconi anemia pathway_Homo sapiens_hsa034602.19877025
20Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.69914353
21RNA degradation_Homo sapiens_hsa030181.67092376
22Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.60391612
23mRNA surveillance pathway_Homo sapiens_hsa030151.56168545
24Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.55084395
25Alzheimers disease_Homo sapiens_hsa050101.54465843
26Purine metabolism_Homo sapiens_hsa002301.51821285
27Folate biosynthesis_Homo sapiens_hsa007901.48811864
28p53 signaling pathway_Homo sapiens_hsa041151.48527870
29Pentose phosphate pathway_Homo sapiens_hsa000301.37971012
30Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.32784485
31Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.31223935
32Non-homologous end-joining_Homo sapiens_hsa034501.30417376
33Regulation of autophagy_Homo sapiens_hsa041401.26541017
34Oocyte meiosis_Homo sapiens_hsa041141.23510603
35Cysteine and methionine metabolism_Homo sapiens_hsa002701.22574703
36Epstein-Barr virus infection_Homo sapiens_hsa051691.21548366
37Fructose and mannose metabolism_Homo sapiens_hsa000511.20079350
38Cardiac muscle contraction_Homo sapiens_hsa042601.19527424
39Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.17767790
40Steroid hormone biosynthesis_Homo sapiens_hsa001401.15324818
41Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.11696378
42Biosynthesis of amino acids_Homo sapiens_hsa012301.02388077
43Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.02325465
44Drug metabolism - other enzymes_Homo sapiens_hsa009831.01062709
452-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.88950928
46Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.86409686
47Fatty acid elongation_Homo sapiens_hsa000620.85521247
48Selenocompound metabolism_Homo sapiens_hsa004500.84671480
49Vibrio cholerae infection_Homo sapiens_hsa051100.84249395
50Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.82646522
51Huntingtons disease_Homo sapiens_hsa050160.80109729
52Synaptic vesicle cycle_Homo sapiens_hsa047210.79326599
53Carbon metabolism_Homo sapiens_hsa012000.77592384
54Glutathione metabolism_Homo sapiens_hsa004800.76973059
55SNARE interactions in vesicular transport_Homo sapiens_hsa041300.75288177
56Cyanoamino acid metabolism_Homo sapiens_hsa004600.72314679
57Glycerophospholipid metabolism_Homo sapiens_hsa005640.71357042
58Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.65928787
59Chemical carcinogenesis_Homo sapiens_hsa052040.61688229
60Starch and sucrose metabolism_Homo sapiens_hsa005000.60039085
61Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.57658106
62Vitamin digestion and absorption_Homo sapiens_hsa049770.57383567
63Caffeine metabolism_Homo sapiens_hsa002320.56544515
64Pyruvate metabolism_Homo sapiens_hsa006200.55609754
65Linoleic acid metabolism_Homo sapiens_hsa005910.55119607
66Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.53761138
67Arachidonic acid metabolism_Homo sapiens_hsa005900.51773175
68Galactose metabolism_Homo sapiens_hsa000520.51686835
69N-Glycan biosynthesis_Homo sapiens_hsa005100.51649152
70Arginine and proline metabolism_Homo sapiens_hsa003300.50653710
71Olfactory transduction_Homo sapiens_hsa047400.50492428
72Metabolic pathways_Homo sapiens_hsa011000.48200554
73Sulfur relay system_Homo sapiens_hsa041220.47439881
74Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.46426281
75Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.45759103
76Viral carcinogenesis_Homo sapiens_hsa052030.45227564
77Hippo signaling pathway_Homo sapiens_hsa043900.42564898
78Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.42513516
79Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.41986567
80Systemic lupus erythematosus_Homo sapiens_hsa053220.39152107
81Parkinsons disease_Homo sapiens_hsa050120.38492048
82alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.37676184
83Alcoholism_Homo sapiens_hsa050340.37375888
84Oxidative phosphorylation_Homo sapiens_hsa001900.36525320
85Sulfur metabolism_Homo sapiens_hsa009200.35529768
86Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.35041715
87Propanoate metabolism_Homo sapiens_hsa006400.31402720
88Herpes simplex infection_Homo sapiens_hsa051680.30262461
89Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.30020524
90mTOR signaling pathway_Homo sapiens_hsa041500.29993095
91Antigen processing and presentation_Homo sapiens_hsa046120.29557802
92Tight junction_Homo sapiens_hsa045300.29033670
93HTLV-I infection_Homo sapiens_hsa051660.27853271
94Renin-angiotensin system_Homo sapiens_hsa046140.25599138
95Hedgehog signaling pathway_Homo sapiens_hsa043400.24096755
96Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.21908991
97MicroRNAs in cancer_Homo sapiens_hsa052060.21045234
98Thyroid cancer_Homo sapiens_hsa052160.20768174
99Tyrosine metabolism_Homo sapiens_hsa003500.20246874
100Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.19862351
101Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.19289957
102Steroid biosynthesis_Homo sapiens_hsa001000.18036853
103TGF-beta signaling pathway_Homo sapiens_hsa043500.16680754
104Rheumatoid arthritis_Homo sapiens_hsa053230.16552492
105Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.14000983
106Fat digestion and absorption_Homo sapiens_hsa049750.13306506
107Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.12657195
108Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.11743070
109beta-Alanine metabolism_Homo sapiens_hsa004100.11399824
110Protein export_Homo sapiens_hsa030600.10744991
111Glycerolipid metabolism_Homo sapiens_hsa005610.10395450
112RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.08938006
113Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.08185660
114Small cell lung cancer_Homo sapiens_hsa052220.07918919
115HIF-1 signaling pathway_Homo sapiens_hsa040660.07251327
116Circadian rhythm_Homo sapiens_hsa047100.07131014
117Phenylalanine metabolism_Homo sapiens_hsa003600.06938008
118Basal cell carcinoma_Homo sapiens_hsa052170.05020332
119Lysosome_Homo sapiens_hsa041420.04814482
120Renal cell carcinoma_Homo sapiens_hsa052110.02743944
121Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.02718077
122Longevity regulating pathway - mammal_Homo sapiens_hsa042110.02176550
123Sphingolipid metabolism_Homo sapiens_hsa006000.01521411
124Ether lipid metabolism_Homo sapiens_hsa005650.00763787
125Legionellosis_Homo sapiens_hsa051340.00700488
126Mineral absorption_Homo sapiens_hsa04978-0.0257235
127Pentose and glucuronate interconversions_Homo sapiens_hsa00040-0.0218150
128Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932-0.0173239
129FoxO signaling pathway_Homo sapiens_hsa04068-0.0140625
130Apoptosis_Homo sapiens_hsa04210-0.0096278
131Retinol metabolism_Homo sapiens_hsa00830-0.0066224

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