FNDC3B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1collagen fibril organization (GO:0030199)5.37192822
2protein heterotrimerization (GO:0070208)4.45556517
3endodermal cell differentiation (GO:0035987)4.13112220
4cell adhesion mediated by integrin (GO:0033627)4.07982618
5Golgi transport vesicle coating (GO:0048200)3.95958677
6COPI coating of Golgi vesicle (GO:0048205)3.95958677
7apoptotic cell clearance (GO:0043277)3.91831737
8keratan sulfate catabolic process (GO:0042340)3.90994693
9collagen metabolic process (GO:0032963)3.90749854
10regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.89787827
11chondrocyte development (GO:0002063)3.87726654
12collagen catabolic process (GO:0030574)3.85967199
13chondrocyte proliferation (GO:0035988)3.85758033
14cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.72617743
15multicellular organismal macromolecule metabolic process (GO:0044259)3.70761349
16skin morphogenesis (GO:0043589)3.68696548
17maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.66731697
18retina vasculature morphogenesis in camera-type eye (GO:0061299)3.62859377
19multicellular organismal catabolic process (GO:0044243)3.61848939
20multicellular organismal metabolic process (GO:0044236)3.57550621
21basement membrane organization (GO:0071711)3.54176255
22axon extension involved in axon guidance (GO:0048846)3.53485768
23neuron projection extension involved in neuron projection guidance (GO:1902284)3.53485768
24extracellular matrix disassembly (GO:0022617)3.44447829
25wound healing, spreading of epidermal cells (GO:0035313)3.43226472
26negative regulation of fibrinolysis (GO:0051918)3.41138252
27negative regulation of fatty acid transport (GO:2000192)3.33754416
28vascular endothelial growth factor signaling pathway (GO:0038084)3.33719891
29protein retention in ER lumen (GO:0006621)3.33440874
30endothelial cell morphogenesis (GO:0001886)3.29848625
31glomerular basement membrane development (GO:0032836)3.29504521
32regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.27102851
33bone trabecula formation (GO:0060346)3.18914413
34insulin-like growth factor receptor signaling pathway (GO:0048009)3.15517068
35cellular response to vitamin (GO:0071295)3.14516252
36cellular response to vitamin D (GO:0071305)3.08852144
37positive regulation of p38MAPK cascade (GO:1900745)3.08534374
38regulation of transforming growth factor beta2 production (GO:0032909)3.08203543
39positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr3.07650870
40sequestering of extracellular ligand from receptor (GO:0035581)3.06021017
41positive regulation of endothelial cell apoptotic process (GO:2000353)3.03471040
42positive regulation of membrane protein ectodomain proteolysis (GO:0051044)3.02655869
43negative regulation of protein activation cascade (GO:2000258)3.01235389
44peptidyl-proline hydroxylation (GO:0019511)3.01029404
45regulation of apoptotic cell clearance (GO:2000425)3.00458253
46COPII vesicle coating (GO:0048208)2.98830700
47regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.95686980
48hypotonic response (GO:0006971)2.94155385
49negative regulation of complement activation (GO:0045916)2.93860938
50pathway-restricted SMAD protein phosphorylation (GO:0060389)2.92255920
51regulation of membrane protein ectodomain proteolysis (GO:0051043)2.87162652
52negative regulation of chondrocyte differentiation (GO:0032331)2.85694677
53wound healing, spreading of cells (GO:0044319)2.81744490
54protein localization to endosome (GO:0036010)2.78669419
55extracellular matrix organization (GO:0030198)2.78151119
56plasma membrane repair (GO:0001778)2.77989980
57mesenchymal-epithelial cell signaling (GO:0060638)2.77933440
58cell migration involved in sprouting angiogenesis (GO:0002042)2.77215341
59extracellular structure organization (GO:0043062)2.77083806
60positive regulation of osteoblast proliferation (GO:0033690)2.76031205
61iron ion import (GO:0097286)2.75992119
62positive regulation of extracellular matrix organization (GO:1903055)2.75904956
63endocardial cushion development (GO:0003197)2.75570840
64activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.74555979
65regulation of complement activation (GO:0030449)2.72294149
66hippo signaling (GO:0035329)2.71754017
67protein hydroxylation (GO:0018126)2.71287309
68regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.70352048
69glomerular visceral epithelial cell development (GO:0072015)2.70161114
70interleukin-6-mediated signaling pathway (GO:0070102)2.69126621
71branching involved in salivary gland morphogenesis (GO:0060445)2.67764959
72regulation of protein activation cascade (GO:2000257)2.66357040
73detection of molecule of bacterial origin (GO:0032490)2.65895444
74regulation of fibrinolysis (GO:0051917)2.65835225
75pinocytosis (GO:0006907)2.63789567
76cell-substrate junction assembly (GO:0007044)2.63060238
77exocrine pancreas development (GO:0031017)2.62911124
78negative regulation of cartilage development (GO:0061037)2.62651096
79renal filtration (GO:0097205)2.61293986
80positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.61118085
81growth hormone receptor signaling pathway (GO:0060396)2.59484827
82substrate-dependent cell migration (GO:0006929)2.59380537
83positive regulation vascular endothelial growth factor production (GO:0010575)2.57172811
84regulation of plasminogen activation (GO:0010755)2.56759117
85regulation of transforming growth factor beta1 production (GO:0032908)2.55838440
86positive regulation of nuclease activity (GO:0032075)2.54963396
87negative regulation of smooth muscle cell migration (GO:0014912)2.54932658
88membrane raft organization (GO:0031579)2.54605938
89positive regulation of hormone biosynthetic process (GO:0046886)2.53367696
90epithelial cell-cell adhesion (GO:0090136)2.52220210
91negative regulation of anoikis (GO:2000811)2.51091172
92hemidesmosome assembly (GO:0031581)2.49607871
93regulation of macrophage chemotaxis (GO:0010758)2.48847178
94regulation of integrin-mediated signaling pathway (GO:2001044)2.48205007
95endoplasmic reticulum unfolded protein response (GO:0030968)2.47985038
96positive regulation of hemostasis (GO:1900048)2.47632438
97positive regulation of blood coagulation (GO:0030194)2.47632438
98positive regulation of heterotypic cell-cell adhesion (GO:0034116)2.46462857
99positive regulation of coagulation (GO:0050820)2.45361356
100hyaluronan catabolic process (GO:0030214)2.45163139
101dermatan sulfate biosynthetic process (GO:0030208)2.43990772
102fibrinolysis (GO:0042730)2.41760603
103regulation of vascular endothelial growth factor production (GO:0010574)2.41014905
104metanephric mesenchyme development (GO:0072075)2.40602089
105regulation of cartilage development (GO:0061035)2.40554784
106response to fluid shear stress (GO:0034405)2.40526617
107glomerular filtration (GO:0003094)2.40078541
108positive regulation of cartilage development (GO:0061036)2.39033490
109cellular response to unfolded protein (GO:0034620)2.38993737
110glomerular epithelial cell development (GO:0072310)2.38337578
111lymphangiogenesis (GO:0001946)2.38282441
112low-density lipoprotein particle clearance (GO:0034383)2.38227238
113positive regulation of glycogen biosynthetic process (GO:0045725)2.36878782
114atrioventricular valve morphogenesis (GO:0003181)2.36454019
115UDP-N-acetylglucosamine metabolic process (GO:0006047)2.36252919
116regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.36198385
117platelet-derived growth factor receptor signaling pathway (GO:0048008)2.36051217
118smooth muscle tissue development (GO:0048745)2.35318333
119cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.34513696
120blood vessel maturation (GO:0001955)2.34436927
121pericardium development (GO:0060039)2.34219924
122cellular response to ethanol (GO:0071361)2.32632282
123positive regulation of epithelial to mesenchymal transition (GO:0010718)2.32185248
124endochondral ossification (GO:0001958)2.31791259
125replacement ossification (GO:0036075)2.31791259
126oligosaccharide catabolic process (GO:0009313)2.31482308
127regulation of chondrocyte differentiation (GO:0032330)2.31350114
128regulation of endothelial cell apoptotic process (GO:2000351)2.30705770
129vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.30619361
130cell aggregation (GO:0098743)2.29978008
131cartilage condensation (GO:0001502)2.29978008
132ER-nucleus signaling pathway (GO:0006984)2.29568622
133cellular response to interferon-alpha (GO:0035457)2.29205542
134positive regulation of transforming growth factor beta production (GO:0071636)2.28657703
135regulation of p38MAPK cascade (GO:1900744)2.28604814
136venous blood vessel morphogenesis (GO:0048845)2.28301022
137* substrate adhesion-dependent cell spreading (GO:0034446)2.27703694
138protein localization to cell surface (GO:0034394)2.27013264
139cell-matrix adhesion (GO:0007160)2.26917957
140regulation of transforming growth factor beta production (GO:0071634)2.26807441
141cellular response to growth hormone stimulus (GO:0071378)2.26415990
142regulation of collagen metabolic process (GO:0010712)2.26204275
143dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.25997144
144protein carboxylation (GO:0018214)2.25128568
145peptidyl-glutamic acid carboxylation (GO:0017187)2.25128568
146regulation of nuclease activity (GO:0032069)2.25122154
147craniofacial suture morphogenesis (GO:0097094)2.25083764
148mesodermal cell differentiation (GO:0048333)2.24560429
149regulation of mononuclear cell migration (GO:0071675)2.24275550
150regulation of vitamin D biosynthetic process (GO:0060556)2.24150416
151regulation of collagen biosynthetic process (GO:0032965)2.20613960

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human5.81862489
2TP63_17297297_ChIP-ChIP_HaCaT_Human4.50585296
3RARG_19884340_ChIP-ChIP_MEFs_Mouse3.47564796
4CLOCK_20551151_ChIP-Seq_293T_Human2.81871045
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.71436044
6* ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.52009703
7ESR1_21235772_ChIP-Seq_MCF-7_Human2.48512769
8* CJUN_26792858_Chip-Seq_BT549_Human2.39378873
9* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.37567302
10* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse2.31996137
11* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse2.19305382
12EP300_21415370_ChIP-Seq_HL-1_Mouse2.18571611
13TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.17660523
14WT1_19549856_ChIP-ChIP_CCG9911_Human2.13184313
15PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.09015417
16CDX2_19796622_ChIP-Seq_MESCs_Mouse2.08594574
17SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.06608417
18NRF2_20460467_ChIP-Seq_MEFs_Mouse2.04747858
19NFE2L2_20460467_ChIP-Seq_MEFs_Mouse2.04747858
20RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.98421654
21HIF1A_21447827_ChIP-Seq_MCF-7_Human1.98101461
22* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.95720315
23* BRD4_25478319_ChIP-Seq_HGPS_Human1.94058279
24SMAD_19615063_ChIP-ChIP_OVARY_Human1.92311053
25STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.89006663
26* PPAR_26484153_Chip-Seq_NCI-H1993_Human1.87649399
27ESR2_21235772_ChIP-Seq_MCF-7_Human1.87330996
28EGR1_19374776_ChIP-ChIP_THP-1_Human1.86216065
29FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.82969850
30CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.73325526
31GATA2_21666600_ChIP-Seq_HMVEC_Human1.70430637
32Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.69161642
33FOXO3_23340844_ChIP-Seq_DLD1_Human1.67929932
34SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.66551077
35SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.66551077
36* SOX2_20726797_ChIP-Seq_SW620_Human1.64577891
37* SALL4_18804426_ChIP-ChIP_XEN_Mouse1.63866275
38* MYB_21317192_ChIP-Seq_ERMYB_Mouse1.57013981
39RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.55585472
40EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.54312555
41SOX9_24532713_ChIP-Seq_HFSC_Mouse1.53786227
42TP53_18474530_ChIP-ChIP_U2OS_Human1.50323245
43FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.46512375
44TP53_16413492_ChIP-PET_HCT116_Human1.46090922
45* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.44379155
46JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.40526649
47SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.39979037
48STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.39597858
49* NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.38892929
50ESR1_20079471_ChIP-ChIP_T-47D_Human1.37922864
51JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.35791160
52TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.32407865
53IRF8_27001747_Chip-Seq_BMDM_Mouse1.32127868
54SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.31008046
55* LXR_22158963_ChIP-Seq_LIVER_Mouse1.29204130
56TBX20_22328084_ChIP-Seq_HEART_Mouse1.28669117
57TBX20_22080862_ChIP-Seq_HEART_Mouse1.28669117
58FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.27074789
59BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.26333770
60VDR_24787735_ChIP-Seq_THP-1_Human1.23485285
61* UBF1/2_26484160_Chip-Seq_HMECs_Human1.22614483
62KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.22102397
63TCF4_18268006_ChIP-ChIP_LS174T_Human1.22076294
64BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.21850432
65TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.17577841
66IRF8_22096565_ChIP-ChIP_GC-B_Human1.17494145
67NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.17387169
68P300_27058665_Chip-Seq_ZR-75-30cells_Human1.17027506
69* NFIB_24661679_ChIP-Seq_LUNG_Mouse1.14921551
70* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.10462591
71ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.10286416
72* AHR_22903824_ChIP-Seq_MCF-7_Human1.09979908
73TP63_23658742_ChIP-Seq_EP156T_Human1.08807044
74* PIAS1_25552417_ChIP-Seq_VCAP_Human1.08400659
75* ISL1_27105846_Chip-Seq_CPCs_Mouse1.06988806
76* FOXA2_19822575_ChIP-Seq_HepG2_Human1.03966074
77PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.03014672
78* NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.01942722
79ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.01532828
80PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.01513829
81RXR_22108803_ChIP-Seq_LS180_Human1.00339948
82RXR_22158963_ChIP-Seq_LIVER_Mouse1.00305671
83PPARA_22158963_ChIP-Seq_LIVER_Mouse0.99443876
84ELK3_25401928_ChIP-Seq_HUVEC_Human0.99052046
85SOX2_27498859_Chip-Seq_STOMACH_Mouse0.99040224
86FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.98620887
87GATA1_22025678_ChIP-Seq_K562_Human0.96550891
88* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.95508178
89TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.94602229
90* ARNT_22903824_ChIP-Seq_MCF-7_Human0.94213880
91MEF2A_21415370_ChIP-Seq_HL-1_Mouse0.94082746
92KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.93336816
93SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.92948006
94GATA3_24758297_ChIP-Seq_MCF-7_Human0.92583545
95STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.92427438
96GATA4_25053715_ChIP-Seq_YYC3_Human0.92243944
97* SMC1_22415368_ChIP-Seq_MEFs_Mouse0.92192039
98ATF3_27146783_Chip-Seq_COLON_Human0.91195311
99SMAD3_21741376_ChIP-Seq_HESCs_Human0.90743422
100FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.90642084
101* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.90585961
102PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.89348358
103NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.88950705
104HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.88865810
105WT1_25993318_ChIP-Seq_PODOCYTE_Human0.88197032
106ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.87536528
107FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.87442881
108CDX2_20551321_ChIP-Seq_CACO-2_Human0.87228973
109CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.87113531
110* PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.86913983
111* CDX2_22108803_ChIP-Seq_LS180_Human0.86171665
112* FOXM1_26456572_ChIP-Seq_MCF-7_Human0.85896633
113DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.85770598
114PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.85585252
115BP1_19119308_ChIP-ChIP_Hs578T_Human0.85451095
116ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.85334466
117CTNNB1_20460455_ChIP-Seq_HCT116_Human0.84782780
118IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.84673184
119* NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.84513598
120SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.84438842
121STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.84354621
122RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.83292989

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen6.65734459
2MP0005503_abnormal_tendon_morphology4.41774353
3MP0005275_abnormal_skin_tensile4.16446264
4MP0003705_abnormal_hypodermis_morpholog3.75308493
5MP0004272_abnormal_basement_membrane3.42520592
6MP0003279_aneurysm2.93793901
7MP0001958_emphysema2.57260003
8MP0006054_spinal_hemorrhage2.43376365
9MP0009384_cardiac_valve_regurgitation2.37587849
10MP0005623_abnormal_meninges_morphology2.18741861
11* MP0003566_abnormal_cell_adhesion2.05076134
12MP0005508_abnormal_skeleton_morphology1.98515012
13MP0005257_abnormal_intraocular_pressure1.97987435
14MP0010368_abnormal_lymphatic_system1.93308454
15MP0002896_abnormal_bone_mineralization1.91765041
16MP0002877_abnormal_melanocyte_morpholog1.78534215
17MP0002295_abnormal_pulmonary_circulatio1.78525702
18MP0002060_abnormal_skin_morphology1.76751023
19MP0009780_abnormal_chondrocyte_physiolo1.76747213
20MP0005023_abnormal_wound_healing1.73465889
21MP0010352_gastrointestinal_tract_polyps1.70030408
22MP0000013_abnormal_adipose_tissue1.64051409
23MP0003045_fibrosis1.59159842
24MP0002108_abnormal_muscle_morphology1.58045215
25MP0003191_abnormal_cellular_cholesterol1.57020441
26MP0009840_abnormal_foam_cell1.54990812
27* MP0003091_abnormal_cell_migration1.54393855
28MP0002282_abnormal_trachea_morphology1.51755222
29MP0001299_abnormal_eye_distance/1.51220292
30MP0000163_abnormal_cartilage_morphology1.50222963
31MP0003300_gastrointestinal_ulcer1.50196505
32MP0002933_joint_inflammation1.47535356
33MP0001879_abnormal_lymphatic_vessel1.46861891
34MP0005390_skeleton_phenotype1.45301146
35MP0009250_abnormal_appendicular_skeleto1.43167230
36MP0000767_abnormal_smooth_muscle1.42626485
37MP0004134_abnormal_chest_morphology1.42560471
38MP0001542_abnormal_bone_strength1.42366324
39MP0003283_abnormal_digestive_organ1.41678721
40MP0003303_peritoneal_inflammation1.40631299
41MP0002115_abnormal_skeleton_extremities1.39533584
42MP0001533_abnormal_skeleton_physiology1.33427096
43MP0000733_abnormal_muscle_development1.29915846
44MP0002998_abnormal_bone_remodeling1.29317566
45MP0002168_other_aberrant_phenotype1.26454024
46MP0002139_abnormal_hepatobiliary_system1.25263147
47MP0003453_abnormal_keratinocyte_physiol1.20827691
48MP0003385_abnormal_body_wall1.19750813
49* MP0002113_abnormal_skeleton_development1.17188508
50MP0005409_darkened_coat_color1.16640129
51MP0000003_abnormal_adipose_tissue1.14023784
52MP0001243_abnormal_dermal_layer1.12752393
53MP0003795_abnormal_bone_structure1.11325953
54MP0008004_abnormal_stomach_pH1.10777234
55MP0006082_CNS_inflammation1.06703508
56MP0004883_abnormal_blood_vessel1.04452114
57MP0003172_abnormal_lysosome_physiology1.02605817
58* MP0005076_abnormal_cell_differentiation1.02050195
59MP0005164_abnormal_response_to1.02025573
60MP0004510_myositis0.99648433
61MP0003868_abnormal_feces_composition0.98862412
62MP0003942_abnormal_urinary_system0.98395542
63MP0005451_abnormal_body_composition0.98018000
64MP0000569_abnormal_digit_pigmentation0.97966141
65MP0009053_abnormal_anal_canal0.97838047
66MP0003115_abnormal_respiratory_system0.97712669
67MP0000428_abnormal_craniofacial_morphol0.96214608
68MP0003436_decreased_susceptibility_to0.93222800
69MP0004185_abnormal_adipocyte_glucose0.93108503
70MP0005165_increased_susceptibility_to0.92687990
71MP0002128_abnormal_blood_circulation0.91731376
72MP0000750_abnormal_muscle_regeneration0.91716182
73MP0000249_abnormal_blood_vessel0.90063801
74MP0000858_altered_metastatic_potential0.89970323
75MP0004084_abnormal_cardiac_muscle0.89418163
76MP0010234_abnormal_vibrissa_follicle0.88750094
77MP0005375_adipose_tissue_phenotype0.88201668
78MP0005167_abnormal_blood-brain_barrier0.87790575
79MP0002109_abnormal_limb_morphology0.87113120
80MP0003941_abnormal_skin_development0.85218484
81MP0000534_abnormal_ureter_morphology0.85040970
82MP0010030_abnormal_orbit_morphology0.83633310
83MP0004233_abnormal_muscle_weight0.83362333
84MP0000343_altered_response_to0.83335917
85MP0003828_pulmonary_edema0.83022612
86MP0005248_abnormal_Harderian_gland0.82865779
87MP0003935_abnormal_craniofacial_develop0.82849778
88MP0001915_intracranial_hemorrhage0.82722472
89MP0003755_abnormal_palate_morphology0.81417795
90MP0005220_abnormal_exocrine_pancreas0.81080307
91MP0006138_congestive_heart_failure0.80923331
92MP0002332_abnormal_exercise_endurance0.80834384
93MP0001614_abnormal_blood_vessel0.80735302
94MP0003195_calcinosis0.80237509
95MP0003448_altered_tumor_morphology0.79855405
96MP0000432_abnormal_head_morphology0.79485943
97MP0000751_myopathy0.76424293
98MP0000537_abnormal_urethra_morphology0.75921973
99MP0002925_abnormal_cardiovascular_devel0.75385588
100MP0003075_altered_response_to0.75295676
101MP0001175_abnormal_lung_morphology0.74228083
102MP0002932_abnormal_joint_morphology0.74202275
103MP0003252_abnormal_bile_duct0.73604320
104MP0000762_abnormal_tongue_morphology0.73080229
105MP0008775_abnormal_heart_ventricle0.72742930
106MP0000516_abnormal_urinary_system0.71782878
107MP0005367_renal/urinary_system_phenotyp0.71782878
108MP0002116_abnormal_craniofacial_bone0.71340987
109MP0002089_abnormal_postnatal_growth/wei0.71132990
110MP0005666_abnormal_adipose_tissue0.70956270
111MP0005595_abnormal_vascular_smooth0.70642303
112MP0002419_abnormal_innate_immunity0.70037109
113MP0005365_abnormal_bile_salt0.69877250
114MP0005171_absent_coat_pigmentation0.69875421
115MP0001661_extended_life_span0.69454154
116MP0005058_abnormal_lysosome_morphology0.69200850
117MP0003656_abnormal_erythrocyte_physiolo0.68623004
118MP0010630_abnormal_cardiac_muscle0.68419705
119MP0003122_maternal_imprinting0.67855974
120MP0010678_abnormal_skin_adnexa0.67578450
121MP0001851_eye_inflammation0.67551823
122MP0004947_skin_inflammation0.67408996
123MP0000371_diluted_coat_color0.67138511
124MP0000604_amyloidosis0.66651315
125MP0003724_increased_susceptibility_to0.66503122
126MP0002254_reproductive_system_inflammat0.66205815
127MP0005360_urolithiasis0.66072011
128MP0005670_abnormal_white_adipose0.65273490
129MP0003937_abnormal_limbs/digits/tail_de0.64816778
130MP0005197_abnormal_uvea_morphology0.64738073
131MP0004087_abnormal_muscle_fiber0.64720214
132MP0001270_distended_abdomen0.63840452
133MP0003950_abnormal_plasma_membrane0.63119416
134MP0005408_hypopigmentation0.62406671
135MP0005193_abnormal_anterior_eye0.62083759
136MP0002133_abnormal_respiratory_system0.61520736

Predicted human phenotypes

RankGene SetZ-score
1Premature rupture of membranes (HP:0001788)5.90089974
2Protrusio acetabuli (HP:0003179)5.86759780
3Cervical subluxation (HP:0003308)4.20946420
4Aortic dissection (HP:0002647)3.85902310
5Epiphyseal dysplasia (HP:0002656)3.85068700
6Ankle contracture (HP:0006466)3.84878830
7Hypoplastic ischia (HP:0003175)3.84527160
8Atrophic scars (HP:0001075)3.69878693
9Cerebral aneurysm (HP:0004944)3.57278632
10Abnormality of the ischium (HP:0003174)3.51933692
11Shallow orbits (HP:0000586)3.51271446
12Neonatal short-limb short stature (HP:0008921)3.47653813
13Soft skin (HP:0000977)3.37714296
14Aortic aneurysm (HP:0004942)3.30720485
15Mitral stenosis (HP:0001718)3.30118648
16Broad metatarsal (HP:0001783)3.28632253
17Peritonitis (HP:0002586)3.10099726
18Deep venous thrombosis (HP:0002625)3.07011878
19Cupped ribs (HP:0000887)3.05997688
20Vertebral compression fractures (HP:0002953)2.97316022
21Mitral valve prolapse (HP:0001634)2.94191131
22Wormian bones (HP:0002645)2.91329002
23Follicular hyperkeratosis (HP:0007502)2.91191373
24Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.88094006
25Dilatation of the ascending aorta (HP:0005111)2.87051512
26Bladder diverticulum (HP:0000015)2.84701879
27Vitreoretinal degeneration (HP:0000655)2.80682483
28Fragile skin (HP:0001030)2.79844347
29Cardiovascular calcification (HP:0011915)2.78613304
30Blue sclerae (HP:0000592)2.75152107
31Osteoarthritis (HP:0002758)2.74554655
32Vascular tortuosity (HP:0004948)2.71938844
33Spinal rigidity (HP:0003306)2.65698731
34Genu recurvatum (HP:0002816)2.64477729
35Complement deficiency (HP:0004431)2.61725854
36Increased connective tissue (HP:0009025)2.61445369
37Flat acetabular roof (HP:0003180)2.58021962
38Abnormality of dentin (HP:0010299)2.52625982
39Abnormality of liposaccharide metabolism (HP:0010968)2.51353340
40Abnormality of glycosphingolipid metabolism (HP:0004343)2.51353340
41Abnormality of glycolipid metabolism (HP:0010969)2.51353340
42Arterial tortuosity (HP:0005116)2.48385245
43Platyspondyly (HP:0000926)2.46811361
44Aneurysm (HP:0002617)2.42719585
45Osteolytic defects of the phalanges of the hand (HP:0009771)2.42253044
46Osteolytic defects of the hand bones (HP:0009699)2.42253044
47Type 1 muscle fiber predominance (HP:0003803)2.39827811
48Exostoses (HP:0100777)2.38210343
49Abnormality of the acetabulum (HP:0003170)2.35931308
50Flared iliac wings (HP:0002869)2.35785586
51Abnormality of the common coagulation pathway (HP:0010990)2.34488372
52Glomerulonephritis (HP:0000099)2.29001245
53Coxa vara (HP:0002812)2.28523262
54Spondylolisthesis (HP:0003302)2.28252289
55Overgrowth (HP:0001548)2.28104003
56Metaphyseal cupping (HP:0003021)2.27838813
57Abnormality of carpal bone ossification (HP:0006257)2.26383804
58Abnormality of complement system (HP:0005339)2.23887897
59Mildly elevated creatine phosphokinase (HP:0008180)2.22819904
60Urinary glycosaminoglycan excretion (HP:0003541)2.22606712
61Mucopolysacchariduria (HP:0008155)2.22606712
62Hyperextensible skin (HP:0000974)2.22479716
63Ulnar bowing (HP:0003031)2.20498324
64Abnormal vertebral ossification (HP:0100569)2.20124601
65Biconcave vertebral bodies (HP:0004586)2.18162233
66Vascular calcification (HP:0004934)2.16536046
67Wrist flexion contracture (HP:0001239)2.16045131
68Beaking of vertebral bodies (HP:0004568)2.15405170
69Thoracolumbar scoliosis (HP:0002944)2.13796465
70Striae distensae (HP:0001065)2.12945475
71Ectopia lentis (HP:0001083)2.11708230
72Bell-shaped thorax (HP:0001591)2.11560099
73Joint laxity (HP:0001388)2.10759569
74Abnormality of mucopolysaccharide metabolism (HP:0011020)2.10730946
75Abnormality of polysaccharide metabolism (HP:0011012)2.10730946
76Abnormality of glycosaminoglycan metabolism (HP:0004371)2.10730946
77Short nail (HP:0001799)2.09244406
78Dysostosis multiplex (HP:0000943)2.09220294
79Aortic regurgitation (HP:0001659)2.08296372
80Asymmetry of the thorax (HP:0001555)2.06712947
81Mesomelia (HP:0003027)2.06149835
82Esophageal varix (HP:0002040)2.05833329
83Tibial bowing (HP:0002982)2.05602355
84Elbow flexion contracture (HP:0002987)2.04484227
85Abnormal ossification of hand bones (HP:0005921)2.03360673
86Abnormality of proline metabolism (HP:0010907)2.03001392
87Hydroxyprolinuria (HP:0003080)2.03001392
88Subacute progressive viral hepatitis (HP:0006572)2.02518158
89Ovoid vertebral bodies (HP:0003300)2.01734582
90Hip contracture (HP:0003273)2.01472501
91Mild short stature (HP:0003502)2.01274159
92Wide anterior fontanel (HP:0000260)2.00319732
93Broad ribs (HP:0000885)1.99873596
94Delayed closure of the anterior fontanelle (HP:0001476)1.98916222
95Abnormal foot bone ossification (HP:0010675)1.98596735
96Hypoplasia of the odontoid process (HP:0003311)1.98568888
97Flat capital femoral epiphysis (HP:0003370)1.96615862
98Right ventricular cardiomyopathy (HP:0011663)1.95473448
99Absent frontal sinuses (HP:0002688)1.94706703
100Femoral bowing (HP:0002980)1.94402718
101Broad long bones (HP:0005622)1.94258806
102Radial bowing (HP:0002986)1.93681286
103Tetraparesis (HP:0002273)1.91333854
104Small epiphyses (HP:0010585)1.91316031
105Knee flexion contracture (HP:0006380)1.89692277
106Spinal cord compression (HP:0002176)1.88655164
107Abnormal hand bone ossification (HP:0010660)1.88079883
108Abnormality of the odontoid process (HP:0003310)1.87853573
109Limited hip movement (HP:0008800)1.87465507
110Protuberant abdomen (HP:0001538)1.87460164
111Skin nodule (HP:0200036)1.86497101
112Abnormal delivery (HP:0001787)1.85764618
113Hypoplasia of the iris (HP:0007676)1.84697689
114Systemic lupus erythematosus (HP:0002725)1.83501720
115Nephritis (HP:0000123)1.83193451
116Mitral regurgitation (HP:0001653)1.83172818
117Irregular epiphyses (HP:0010582)1.82892925
118Menorrhagia (HP:0000132)1.81935400
119Joint stiffness (HP:0001387)1.81814095
120Abnormal tarsal ossification (HP:0008369)1.81254728
121Syringomyelia (HP:0003396)1.81054839
122Spinal cord lesions (HP:0100561)1.81054839
123Myocardial infarction (HP:0001658)1.80423721
124Thin ribs (HP:0000883)1.79209567
125Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.79004107
126Broad face (HP:0000283)1.78768764
127Infantile muscular hypotonia (HP:0008947)1.78426143
128Thin bony cortex (HP:0002753)1.78118633
129Hematochezia (HP:0002573)1.76472207
130Aortic valve stenosis (HP:0001650)1.75174890
131Camptodactyly of toe (HP:0001836)1.73685194
132Nuclear cataract (HP:0100018)1.73213294
133Pulmonary artery stenosis (HP:0004415)1.72967814
134Coarse hair (HP:0002208)1.72677530
135Broad phalanx (HP:0006009)1.72485061
136Abnormality of the distal phalanges of the toes (HP:0010182)1.72300451
137Vacuolated lymphocytes (HP:0001922)1.70961063
138Distal upper limb amyotrophy (HP:0007149)1.68892217
139Upper limb amyotrophy (HP:0009129)1.68892217
140Decreased skull ossification (HP:0004331)1.68749727
141Flattened epiphyses (HP:0003071)1.68262100
142Abnormality of the nasal septum (HP:0000419)1.66000751
143Inguinal hernia (HP:0000023)1.64133429
144Abnormality of the vasculature of the conjunctiva (HP:0008054)1.64128401
145Disproportionate tall stature (HP:0001519)1.63936912

Predicted kinase interactions (KEA)

RankGene SetZ-score
1DDR24.27769636
2LATS13.73578643
3TRIB33.26828587
4ERN12.96044651
5PDGFRA2.88020400
6TTN2.87651415
7SIK12.70347873
8RIPK12.24109737
9AKT32.17005428
10FRK2.08009146
11INSRR2.05956191
12EPHA31.90418621
13PTK61.83759585
14EPHB21.83709330
15FER1.79632709
16STK31.78643185
17MET1.76882692
18PKN21.75511872
19CAMK1D1.73675221
20TRPM71.73569540
21MAP3K31.69271236
22TGFBR21.65112275
23PTK21.62111845
24STK38L1.61064413
25DMPK1.58265328
26NEK91.58061604
27BMX1.52062105
28EPHB11.49823518
29LATS21.46907233
30EPHA21.45022341
31PDGFRB1.39659915
32GRK71.34378450
33CAMK1G1.34161101
34PAK21.31441260
35NUAK11.27437745
36PAK41.25340601
37TAOK31.24684102
38MST1R1.23118364
39PAK31.21728059
40TYK21.16303038
41PIK3CA1.14738869
42JAK11.11031084
43ICK1.06544111
44MTOR1.01928568
45ERBB31.01587077
46STK100.99554965
47IRAK30.99477000
48STK380.87695004
49STK240.87202063
50PIK3CG0.86723524
51MAP2K30.85923238
52ROCK10.85253025
53FGFR30.83182778
54PTK2B0.82680617
55FGFR10.80938316
56MAP3K20.79250592
57CHUK0.79186416
58EIF2AK30.78647587
59CDK120.78597684
60ZAP700.78587008
61PRKG20.77615247
62FGFR40.76398247
63CDK60.75499384
64RPS6KA40.74355454
65ERBB40.73483996
66SCYL20.72880902
67LRRK20.72865445
68PIM20.72658563
69MAP3K60.70783171
70GSK3A0.70372640
71BLK0.70110652
72MYLK0.69910597
73FLT30.67171742
74MAP2K10.66186323
75NTRK10.65698329
76FGFR20.64600464
77FGR0.64287705
78MAP3K140.63248131
79RET0.62941649
80MAP3K70.61050041
81INSR0.61022658
82PRKD30.60746768
83TBK10.58404397
84PRKCH0.57572658
85YES10.57469731
86LMTK20.57341283
87IRAK10.57299163
88TIE10.56760698
89MOS0.56008451
90MAP3K130.55980790
91PRKD10.54591860
92CSK0.54571038
93SGK30.54212887
94IGF1R0.53030511
95CDC42BPA0.53017123
96JAK30.52316396
97BRSK20.52289464
98PRKCE0.52268917
99KIT0.49045577
100ROCK20.48595128
101TGFBR10.48381165
102ABL10.48278638
103MAPK70.46720806
104MATK0.46706567
105STK390.46306564
106PRKD20.45425698
107HIPK20.45387342
108ACVR1B0.44925809
109PLK20.44579195
110BRD40.44303406
111CDK80.43441285
112PRKAA20.43398776
113BMPR1B0.43230748
114BMPR20.43041852
115DYRK1B0.42891091
116KSR10.42240189
117TESK10.41669804
118EGFR0.41141439
119ABL20.40345703
120KSR20.40287784
121CDK90.39418500
122NLK0.39293039
123ERBB20.39042516
124ZAK0.38699805
125SRC0.36873482
126WNK10.36099603
127MAP3K50.34826066
128MELK0.32477985
129MAP3K10.32054868
130WNK40.31908301
131MAPK150.31674465
132ILK0.30290506

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045124.07540345
2Focal adhesion_Homo sapiens_hsa045102.73185358
3Protein digestion and absorption_Homo sapiens_hsa049742.56602749
4Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.47418751
5Amoebiasis_Homo sapiens_hsa051462.10166453
6Adherens junction_Homo sapiens_hsa045202.08824134
7Proteoglycans in cancer_Homo sapiens_hsa052051.97573923
8Malaria_Homo sapiens_hsa051441.96155996
9Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.82082352
10Small cell lung cancer_Homo sapiens_hsa052221.76545968
11AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.75917673
12TGF-beta signaling pathway_Homo sapiens_hsa043501.70760558
13Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.67442353
14Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.65489085
15Dilated cardiomyopathy_Homo sapiens_hsa054141.57508237
16Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.50271903
17Glycosaminoglycan degradation_Homo sapiens_hsa005311.43778169
18PI3K-Akt signaling pathway_Homo sapiens_hsa041511.42952861
19Bladder cancer_Homo sapiens_hsa052191.41150449
20Maturity onset diabetes of the young_Homo sapiens_hsa049501.32498125
21Lysosome_Homo sapiens_hsa041421.29448248
22MicroRNAs in cancer_Homo sapiens_hsa052061.29248245
23Hippo signaling pathway_Homo sapiens_hsa043901.27721905
24Complement and coagulation cascades_Homo sapiens_hsa046101.26205262
25Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.23050185
26Toxoplasmosis_Homo sapiens_hsa051451.22667483
27Prostate cancer_Homo sapiens_hsa052151.22502639
28Chronic myeloid leukemia_Homo sapiens_hsa052201.19800416
29Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.19033627
30TNF signaling pathway_Homo sapiens_hsa046681.17513035
31African trypanosomiasis_Homo sapiens_hsa051431.11804896
32Insulin resistance_Homo sapiens_hsa049311.11130217
33Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.10776149
34Leukocyte transendothelial migration_Homo sapiens_hsa046701.09913546
35Pancreatic cancer_Homo sapiens_hsa052121.07479446
36Phagosome_Homo sapiens_hsa041451.05881103
37Viral myocarditis_Homo sapiens_hsa054161.05556262
38NOD-like receptor signaling pathway_Homo sapiens_hsa046211.04766477
39Regulation of actin cytoskeleton_Homo sapiens_hsa048101.03692449
40Melanoma_Homo sapiens_hsa052181.03275443
41Other glycan degradation_Homo sapiens_hsa005111.01366376
42Staphylococcus aureus infection_Homo sapiens_hsa051501.00118818
43Leishmaniasis_Homo sapiens_hsa051400.97070211
44Basal cell carcinoma_Homo sapiens_hsa052170.94371052
45Sphingolipid metabolism_Homo sapiens_hsa006000.91270093
46Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.87588865
47Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.87237621
48Lysine degradation_Homo sapiens_hsa003100.86701493
49Fatty acid biosynthesis_Homo sapiens_hsa000610.86428764
50N-Glycan biosynthesis_Homo sapiens_hsa005100.85275279
51Jak-STAT signaling pathway_Homo sapiens_hsa046300.85236931
52Ovarian steroidogenesis_Homo sapiens_hsa049130.84946966
53Influenza A_Homo sapiens_hsa051640.84005200
54Osteoclast differentiation_Homo sapiens_hsa043800.82864240
55Hepatitis C_Homo sapiens_hsa051600.82787448
56Pathways in cancer_Homo sapiens_hsa052000.82733102
57Platelet activation_Homo sapiens_hsa046110.82071647
58Dorso-ventral axis formation_Homo sapiens_hsa043200.78625471
59Adipocytokine signaling pathway_Homo sapiens_hsa049200.77333910
60Starch and sucrose metabolism_Homo sapiens_hsa005000.75338347
61Hedgehog signaling pathway_Homo sapiens_hsa043400.75263443
62Protein export_Homo sapiens_hsa030600.75101341
63Renal cell carcinoma_Homo sapiens_hsa052110.74013798
64Longevity regulating pathway - mammal_Homo sapiens_hsa042110.73959834
65Thyroid hormone synthesis_Homo sapiens_hsa049180.71884985
66Toll-like receptor signaling pathway_Homo sapiens_hsa046200.71553346
67Tight junction_Homo sapiens_hsa045300.70618869
68Rap1 signaling pathway_Homo sapiens_hsa040150.69213378
69Pertussis_Homo sapiens_hsa051330.69000712
70Glioma_Homo sapiens_hsa052140.68808392
71mTOR signaling pathway_Homo sapiens_hsa041500.68243883
72RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.68194277
73PPAR signaling pathway_Homo sapiens_hsa033200.68175070
74Renin-angiotensin system_Homo sapiens_hsa046140.67865640
75Type II diabetes mellitus_Homo sapiens_hsa049300.67320365
76Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.65585849
77Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.64622327
78Salmonella infection_Homo sapiens_hsa051320.64553524
79AMPK signaling pathway_Homo sapiens_hsa041520.63932761
80Galactose metabolism_Homo sapiens_hsa000520.63472841
81Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.63166269
82Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.63161650
83Hepatitis B_Homo sapiens_hsa051610.63035952
84FoxO signaling pathway_Homo sapiens_hsa040680.62682314
85Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.62146342
86Legionellosis_Homo sapiens_hsa051340.61582745
87Endometrial cancer_Homo sapiens_hsa052130.61262365
88Apoptosis_Homo sapiens_hsa042100.61189206
89HIF-1 signaling pathway_Homo sapiens_hsa040660.59143547
90Tuberculosis_Homo sapiens_hsa051520.59088534
91Thyroid cancer_Homo sapiens_hsa052160.58981321
92Notch signaling pathway_Homo sapiens_hsa043300.58594763
93Measles_Homo sapiens_hsa051620.57575314
94Central carbon metabolism in cancer_Homo sapiens_hsa052300.56457107
95Shigellosis_Homo sapiens_hsa051310.55613567
96Sulfur metabolism_Homo sapiens_hsa009200.55046144
97ABC transporters_Homo sapiens_hsa020100.54795339
98Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.54748885
99Rheumatoid arthritis_Homo sapiens_hsa053230.54610664
100Estrogen signaling pathway_Homo sapiens_hsa049150.54183700
101Thyroid hormone signaling pathway_Homo sapiens_hsa049190.53921043
102Wnt signaling pathway_Homo sapiens_hsa043100.53236924
103HTLV-I infection_Homo sapiens_hsa051660.52304724
104Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.52239376
105Mineral absorption_Homo sapiens_hsa049780.51369860
106Non-small cell lung cancer_Homo sapiens_hsa052230.51046208
107Prion diseases_Homo sapiens_hsa050200.49579850
108Acute myeloid leukemia_Homo sapiens_hsa052210.47769478
109Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.47595657
110Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.47486242
111Prolactin signaling pathway_Homo sapiens_hsa049170.45753033
112NF-kappa B signaling pathway_Homo sapiens_hsa040640.44929529
113Neurotrophin signaling pathway_Homo sapiens_hsa047220.44701784
114Melanogenesis_Homo sapiens_hsa049160.44303803
115Phospholipase D signaling pathway_Homo sapiens_hsa040720.44252854
116Insulin signaling pathway_Homo sapiens_hsa049100.44004431
117Vibrio cholerae infection_Homo sapiens_hsa051100.43173315
118VEGF signaling pathway_Homo sapiens_hsa043700.42780350
119cGMP-PKG signaling pathway_Homo sapiens_hsa040220.42160195
120Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.42127885
121Caffeine metabolism_Homo sapiens_hsa002320.42023901

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