Rank | Gene Set | Z-score |
---|---|---|
1 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 6.22867512 |
2 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 6.22867512 |
3 | modulation by symbiont of host immune response (GO:0052553) | 6.22867512 |
4 | positive regulation by symbiont of host defense response (GO:0052509) | 6.22867512 |
5 | modulation by symbiont of host defense response (GO:0052031) | 6.22867512 |
6 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 6.22867512 |
7 | regulation of interferon-beta biosynthetic process (GO:0045357) | 5.35750072 |
8 | negative regulation of interleukin-12 production (GO:0032695) | 5.35597309 |
9 | neutrophil activation involved in immune response (GO:0002283) | 5.29077100 |
10 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 5.06883706 |
11 | regulation of mononuclear cell migration (GO:0071675) | 4.96531320 |
12 | pinocytosis (GO:0006907) | 4.82561278 |
13 | immunoglobulin mediated immune response (GO:0016064) | 4.76626572 |
14 | positive regulation of interferon-alpha production (GO:0032727) | 4.42354297 |
15 | regulation of macrophage chemotaxis (GO:0010758) | 4.36136142 |
16 | glycosphingolipid catabolic process (GO:0046479) | 4.32077705 |
17 | regulation of interferon-alpha production (GO:0032647) | 4.28205192 |
18 | virion attachment to host cell (GO:0019062) | 4.26196579 |
19 | adhesion of symbiont to host cell (GO:0044650) | 4.26196579 |
20 | lymphocyte chemotaxis (GO:0048247) | 4.23292403 |
21 | complement activation, alternative pathway (GO:0006957) | 4.22152397 |
22 | macrophage activation involved in immune response (GO:0002281) | 4.22095052 |
23 | amyloid precursor protein catabolic process (GO:0042987) | 4.13430763 |
24 | regulation of cytokine secretion involved in immune response (GO:0002739) | 4.07661816 |
25 | regulation of vitamin D biosynthetic process (GO:0060556) | 4.05052521 |
26 | respiratory burst (GO:0045730) | 4.04493694 |
27 | oligosaccharide catabolic process (GO:0009313) | 4.01573059 |
28 | microglial cell activation (GO:0001774) | 3.97979241 |
29 | positive regulation of chemokine biosynthetic process (GO:0045080) | 3.96589181 |
30 | cellular extravasation (GO:0045123) | 3.96095882 |
31 | positive regulation of heat generation (GO:0031652) | 3.95051005 |
32 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.94849689 |
33 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.94154119 |
34 | response to host immune response (GO:0052572) | 3.94154119 |
35 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.90659444 |
36 | response to peptidoglycan (GO:0032494) | 3.90085726 |
37 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 3.88876268 |
38 | positive regulation of antigen processing and presentation (GO:0002579) | 3.88254785 |
39 | amino sugar catabolic process (GO:0046348) | 3.88101480 |
40 | glycolipid catabolic process (GO:0019377) | 3.87027858 |
41 | myeloid dendritic cell differentiation (GO:0043011) | 3.82329055 |
42 | regulation of cholesterol storage (GO:0010885) | 3.79451896 |
43 | monocyte chemotaxis (GO:0002548) | 3.78749675 |
44 | regulation of fever generation (GO:0031620) | 3.76215227 |
45 | adhesion of symbiont to host (GO:0044406) | 3.75626276 |
46 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.74569545 |
47 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 3.69675157 |
48 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 3.66844080 |
49 | macrophage activation (GO:0042116) | 3.66704686 |
50 | myeloid cell activation involved in immune response (GO:0002275) | 3.64228938 |
51 | regulation of podosome assembly (GO:0071801) | 3.60211296 |
52 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.55432113 |
53 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.55253090 |
54 | negative regulation of granulocyte differentiation (GO:0030853) | 3.54395778 |
55 | positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:0061081 | 3.54299911 |
56 | NIK/NF-kappaB signaling (GO:0038061) | 3.54261957 |
57 | response to host (GO:0075136) | 3.49998625 |
58 | response to host defenses (GO:0052200) | 3.49998625 |
59 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.49998625 |
60 | low-density lipoprotein particle clearance (GO:0034383) | 3.47325345 |
61 | regulation of chemokine biosynthetic process (GO:0045073) | 3.45998935 |
62 | N-acetylneuraminate metabolic process (GO:0006054) | 3.44012281 |
63 | ceramide catabolic process (GO:0046514) | 3.43192290 |
64 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.42772306 |
65 | regulation of chronic inflammatory response (GO:0002676) | 3.35213011 |
66 | eosinophil chemotaxis (GO:0048245) | 3.33998019 |
67 | myeloid dendritic cell activation (GO:0001773) | 3.33938578 |
68 | plasma lipoprotein particle clearance (GO:0034381) | 3.32097686 |
69 | basic amino acid transport (GO:0015802) | 3.30176960 |
70 | regulation of antigen processing and presentation (GO:0002577) | 3.27930881 |
71 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 3.26977990 |
72 | membrane lipid catabolic process (GO:0046466) | 3.26357213 |
73 | branching involved in labyrinthine layer morphogenesis (GO:0060670) | 3.25236228 |
74 | positive regulation of smooth muscle cell migration (GO:0014911) | 3.22556443 |
75 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 3.22410021 |
76 | cellular response to type I interferon (GO:0071357) | 3.22252436 |
77 | type I interferon signaling pathway (GO:0060337) | 3.22252436 |
78 | B cell mediated immunity (GO:0019724) | 3.20480069 |
79 | mast cell activation (GO:0045576) | 3.20131259 |
80 | regulation of vitamin metabolic process (GO:0030656) | 3.19461565 |
81 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.18879306 |
82 | complement activation (GO:0006956) | 3.18595330 |
83 | sphingolipid catabolic process (GO:0030149) | 3.17353637 |
84 | response to protozoan (GO:0001562) | 3.16912006 |
85 | response to type I interferon (GO:0034340) | 3.16749513 |
86 | phagocytosis, engulfment (GO:0006911) | 3.16634253 |
87 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.14150307 |
88 | germinal center formation (GO:0002467) | 3.13660913 |
89 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 3.08226958 |
90 | hyaluronan catabolic process (GO:0030214) | 3.06476612 |
91 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.06211020 |
92 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.06030103 |
93 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 3.05437879 |
94 | positive regulation of cholesterol efflux (GO:0010875) | 3.04248304 |
95 | defense response to protozoan (GO:0042832) | 3.03572756 |
96 | dendritic cell differentiation (GO:0097028) | 3.03062363 |
97 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.02698589 |
98 | cellular response to lipopolysaccharide (GO:0071222) | 3.02613964 |
99 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.01197068 |
100 | regulation of cholesterol esterification (GO:0010872) | 3.00820112 |
101 | cellular response to thyroid hormone stimulus (GO:0097067) | 2.99670504 |
102 | regulation of heat generation (GO:0031650) | 2.99604700 |
103 | negative regulation of inflammatory response to antigenic stimulus (GO:0002862) | 2.97217896 |
104 | positive regulation of leukocyte degranulation (GO:0043302) | 2.96792950 |
105 | response to thyroid hormone (GO:0097066) | 2.95346907 |
106 | positive regulation of macrophage derived foam cell differentiation (GO:0010744) | 2.95253945 |
107 | positive regulation of mast cell activation (GO:0033005) | 2.94933881 |
108 | granulocyte activation (GO:0036230) | 2.94913161 |
109 | positive regulation of macrophage cytokine production (GO:0060907) | 2.94578158 |
110 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.94462941 |
111 | regulation of complement activation (GO:0030449) | 2.94385424 |
112 | negative regulation of myeloid cell apoptotic process (GO:0033033) | 2.94382587 |
113 | response to interferon-alpha (GO:0035455) | 2.93739865 |
114 | negative regulation of production of molecular mediator of immune response (GO:0002701) | 2.93646899 |
115 | lipoxygenase pathway (GO:0019372) | 2.92908175 |
116 | regulation of nitric oxide biosynthetic process (GO:0045428) | 2.92336749 |
117 | cellular response to molecule of bacterial origin (GO:0071219) | 2.92264108 |
118 | regulation of inflammatory response to antigenic stimulus (GO:0002861) | 2.91787721 |
119 | regulation of macrophage derived foam cell differentiation (GO:0010743) | 2.91533659 |
120 | neutrophil activation (GO:0042119) | 2.91127888 |
121 | intracellular pH reduction (GO:0051452) | 2.90764244 |
122 | negative regulation of lipid storage (GO:0010888) | 2.90534457 |
123 | response to muramyl dipeptide (GO:0032495) | 2.89795957 |
124 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 2.87503348 |
125 | eosinophil migration (GO:0072677) | 2.87221391 |
126 | cellular response to interferon-gamma (GO:0071346) | 2.87064895 |
127 | T cell migration (GO:0072678) | 2.86436792 |
128 | regulation of protein activation cascade (GO:2000257) | 2.86292820 |
129 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.86157278 |
130 | positive regulation of sterol transport (GO:0032373) | 2.85748389 |
131 | positive regulation of cholesterol transport (GO:0032376) | 2.85748389 |
132 | positive regulation of NF-kappaB import into nucleus (GO:0042346) | 2.84945661 |
133 | positive regulation of mast cell degranulation (GO:0043306) | 2.84731663 |
134 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 2.84731663 |
135 | adenosine receptor signaling pathway (GO:0001973) | 2.84553733 |
136 | complement activation, classical pathway (GO:0006958) | 2.84534897 |
137 | T-helper 1 type immune response (GO:0042088) | 2.84086697 |
138 | regulation of interleukin-12 production (GO:0032655) | 2.83821196 |
139 | macroautophagy (GO:0016236) | 2.83023420 |
140 | positive regulation of lipid storage (GO:0010884) | 2.82868134 |
141 | phospholipid efflux (GO:0033700) | 2.82455530 |
142 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 2.80341011 |
143 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.80131733 |
144 | positive regulation of interleukin-6 production (GO:0032755) | 2.79985555 |
145 | regulation of mast cell degranulation (GO:0043304) | 2.79891607 |
146 | positive regulation of B cell differentiation (GO:0045579) | 2.77726496 |
147 | positive regulation of type 2 immune response (GO:0002830) | 2.77407248 |
148 | positive regulation of lymphocyte apoptotic process (GO:0070230) | 2.77276461 |
149 | amyloid precursor protein metabolic process (GO:0042982) | 2.76511347 |
150 | positive regulation of monocyte chemotaxis (GO:0090026) | 2.74900826 |
151 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 2.71146129 |
152 | positive regulation of interferon-beta production (GO:0032728) | 2.71096070 |
153 | regulation of macrophage cytokine production (GO:0010935) | 2.70994087 |
154 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.70626271 |
155 | low-density lipoprotein particle remodeling (GO:0034374) | 2.70332530 |
156 | regulation of MHC class II biosynthetic process (GO:0045346) | 2.68494424 |
157 | detection of molecule of bacterial origin (GO:0032490) | 2.68358641 |
158 | apoptotic cell clearance (GO:0043277) | 2.68341202 |
159 | myeloid leukocyte activation (GO:0002274) | 2.67810798 |
160 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.63159756 |
161 | positive regulation of lymphocyte migration (GO:2000403) | 2.62410666 |
162 | positive regulation of phagocytosis (GO:0050766) | 2.61613743 |
163 | neutrophil chemotaxis (GO:0030593) | 2.60051097 |
164 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli | 2.56612046 |
Rank | Gene Set | Z-score |
---|---|---|
1 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 6.17669461 |
2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.95879183 |
3 | * IRF8_27001747_Chip-Seq_BMDM_Mouse | 4.72962052 |
4 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.49185272 |
5 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 4.37531627 |
6 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.72450196 |
7 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 3.61794509 |
8 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 3.50584332 |
9 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 3.40028241 |
10 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 2.81956066 |
11 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.77304622 |
12 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.71579617 |
13 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.58000790 |
14 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.48316255 |
15 | GATA1_22025678_ChIP-Seq_K562_Human | 2.43406520 |
16 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 2.42774896 |
17 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 2.41056816 |
18 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.31422343 |
19 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.19736684 |
20 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.19021096 |
21 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 2.04454813 |
22 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.01620767 |
23 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.95258325 |
24 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.94502266 |
25 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.94054613 |
26 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.92557713 |
27 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.90754344 |
28 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.90175629 |
29 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.88858744 |
30 | SPI1_23127762_ChIP-Seq_K562_Human | 1.85558579 |
31 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.85447962 |
32 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.77871782 |
33 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.72620895 |
34 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.71708134 |
35 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.69974797 |
36 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.68690960 |
37 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.64219763 |
38 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.64054239 |
39 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.62534329 |
40 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.56571544 |
41 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.55694720 |
42 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.54971027 |
43 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.54425670 |
44 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.50355837 |
45 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.49026984 |
46 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.45291711 |
47 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.39842343 |
48 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.35626407 |
49 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.33422230 |
50 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.31363714 |
51 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.31145837 |
52 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.29695456 |
53 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.28564083 |
54 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.27475802 |
55 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.26420753 |
56 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.26144232 |
57 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.25802025 |
58 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.24823633 |
59 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.24484597 |
60 | MAF_26560356_Chip-Seq_TH1_Human | 1.21438728 |
61 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.19951890 |
62 | GATA1_19941826_ChIP-Seq_K562_Human | 1.19778542 |
63 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.19538042 |
64 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.18571689 |
65 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.16954113 |
66 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.16554819 |
67 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.15383034 |
68 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.15064909 |
69 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.14335128 |
70 | * STAT1_20625510_ChIP-Seq_HELA_Human | 1.14205963 |
71 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.13013182 |
72 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.12088597 |
73 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.11112622 |
74 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.10599258 |
75 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.10075521 |
76 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.09839957 |
77 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.09146833 |
78 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.09021308 |
79 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.07186167 |
80 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.06375093 |
81 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.06300707 |
82 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.04326347 |
83 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03996050 |
84 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.03913133 |
85 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.02910659 |
86 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.02087793 |
87 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.02039812 |
88 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.02024474 |
89 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.01372855 |
90 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.01173764 |
91 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.00191920 |
92 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.00099477 |
93 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.99825768 |
94 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.99589287 |
95 | MYB_26560356_Chip-Seq_TH2_Human | 0.99390780 |
96 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.99020228 |
97 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.97929741 |
98 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.97678482 |
99 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.97443792 |
100 | GATA2_19941826_ChIP-Seq_K562_Human | 0.97095498 |
101 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.96852712 |
102 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.96624246 |
103 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.96624246 |
104 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.96562163 |
105 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.95726959 |
106 | MAF_26560356_Chip-Seq_TH2_Human | 0.95211555 |
107 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.95156871 |
108 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.94991341 |
109 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.94139551 |
110 | UTX_26944678_Chip-Seq_JUKART_Human | 0.93349407 |
111 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 0.92972542 |
112 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.92803698 |
113 | GATA3_26560356_Chip-Seq_TH2_Human | 0.92775247 |
114 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.91472871 |
115 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.89888419 |
116 | KDM2B_26808549_Chip-Seq_K562_Human | 0.89080781 |
117 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.87916739 |
118 | MYC_22102868_ChIP-Seq_BL_Human | 0.86234802 |
119 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.84515741 |
120 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.83384518 |
121 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.83227862 |
122 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.83211964 |
123 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.79366992 |
124 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.78504200 |
125 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.77549435 |
126 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.77221756 |
127 | CJUN_26792858_Chip-Seq_BT549_Human | 0.75655015 |
128 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.74953891 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005058_abnormal_lysosome_morphology | 5.31838964 |
2 | MP0009840_abnormal_foam_cell | 4.20480746 |
3 | MP0003436_decreased_susceptibility_to | 3.88124998 |
4 | MP0001835_abnormal_antigen_presentation | 3.56191703 |
5 | MP0006082_CNS_inflammation | 2.99085580 |
6 | MP0002148_abnormal_hypersensitivity_rea | 2.96995627 |
7 | MP0003191_abnormal_cellular_cholesterol | 2.87204102 |
8 | MP0002419_abnormal_innate_immunity | 2.85260018 |
9 | MP0003303_peritoneal_inflammation | 2.77645171 |
10 | MP0003690_abnormal_glial_cell | 2.65981516 |
11 | MP0005000_abnormal_immune_tolerance | 2.56458291 |
12 | MP0003172_abnormal_lysosome_physiology | 2.39903905 |
13 | MP0001533_abnormal_skeleton_physiology | 2.33065227 |
14 | MP0003724_increased_susceptibility_to | 2.27015749 |
15 | MP0009785_altered_susceptibility_to | 2.26036957 |
16 | MP0001790_abnormal_immune_system | 2.24777364 |
17 | MP0005387_immune_system_phenotype | 2.24777364 |
18 | MP0005025_abnormal_response_to | 2.21752135 |
19 | MP0000604_amyloidosis | 2.21070526 |
20 | MP0000343_altered_response_to | 2.19429153 |
21 | MP0004510_myositis | 2.18002463 |
22 | MP0003300_gastrointestinal_ulcer | 2.13002519 |
23 | MP0005464_abnormal_platelet_physiology | 1.97948136 |
24 | MP0001800_abnormal_humoral_immune | 1.95471417 |
25 | MP0000685_abnormal_immune_system | 1.94465522 |
26 | MP0002452_abnormal_antigen_presenting | 1.92434336 |
27 | MP0008004_abnormal_stomach_pH | 1.90647704 |
28 | MP0006054_spinal_hemorrhage | 1.84535195 |
29 | MP0003806_abnormal_nucleotide_metabolis | 1.81548393 |
30 | MP0003075_altered_response_to | 1.80130504 |
31 | MP0008438_abnormal_cutaneous_collagen | 1.77772342 |
32 | MP0005257_abnormal_intraocular_pressure | 1.72765766 |
33 | MP0002723_abnormal_immune_serum | 1.72651327 |
34 | MP0002405_respiratory_system_inflammati | 1.66165557 |
35 | MP0003828_pulmonary_edema | 1.64851362 |
36 | MP0005360_urolithiasis | 1.62155684 |
37 | MP0008469_abnormal_protein_level | 1.62052497 |
38 | MP0003453_abnormal_keratinocyte_physiol | 1.61478664 |
39 | MP0010329_abnormal_lipoprotein_level | 1.60108266 |
40 | MP0002139_abnormal_hepatobiliary_system | 1.58179275 |
41 | MP0009764_decreased_sensitivity_to | 1.57462167 |
42 | MP0001545_abnormal_hematopoietic_system | 1.55373716 |
43 | MP0005397_hematopoietic_system_phenotyp | 1.55373716 |
44 | MP0005451_abnormal_body_composition | 1.55175208 |
45 | MP0001845_abnormal_inflammatory_respons | 1.55067116 |
46 | MP0005671_abnormal_response_to | 1.51951184 |
47 | MP0001819_abnormal_immune_cell | 1.46586973 |
48 | MP0002420_abnormal_adaptive_immunity | 1.46115288 |
49 | MP0005083_abnormal_biliary_tract | 1.45704701 |
50 | MP0005310_abnormal_salivary_gland | 1.44118911 |
51 | MP0005365_abnormal_bile_salt | 1.43713130 |
52 | MP0001853_heart_inflammation | 1.39390959 |
53 | MP0005670_abnormal_white_adipose | 1.31591415 |
54 | MP0000609_abnormal_liver_physiology | 1.31491421 |
55 | MP0003448_altered_tumor_morphology | 1.29136087 |
56 | MP0004947_skin_inflammation | 1.27679071 |
57 | MP0003705_abnormal_hypodermis_morpholog | 1.25016231 |
58 | MP0010155_abnormal_intestine_physiology | 1.24976718 |
59 | MP0004130_abnormal_muscle_cell | 1.24883005 |
60 | MP0005166_decreased_susceptibility_to | 1.24162712 |
61 | MP0001542_abnormal_bone_strength | 1.23432714 |
62 | MP0009763_increased_sensitivity_to | 1.18273556 |
63 | MP0002998_abnormal_bone_remodeling | 1.17879874 |
64 | MP0000465_gastrointestinal_hemorrhage | 1.13719472 |
65 | MP0002332_abnormal_exercise_endurance | 1.13281768 |
66 | MP0002277_abnormal_respiratory_mucosa | 1.07035068 |
67 | MP0005085_abnormal_gallbladder_physiolo | 1.05124424 |
68 | MP0009333_abnormal_splenocyte_physiolog | 1.03872484 |
69 | MP0008875_abnormal_xenobiotic_pharmacok | 1.02374417 |
70 | MP0005390_skeleton_phenotype | 1.01946472 |
71 | MP0002118_abnormal_lipid_homeostasis | 0.99637021 |
72 | MP0010368_abnormal_lymphatic_system | 0.99365463 |
73 | MP0000689_abnormal_spleen_morphology | 0.99295453 |
74 | MP0005164_abnormal_response_to | 0.98393572 |
75 | MP0003195_calcinosis | 0.98392693 |
76 | MP0003566_abnormal_cell_adhesion | 0.96710021 |
77 | MP0000716_abnormal_immune_system | 0.95995030 |
78 | MP0004019_abnormal_vitamin_homeostasis | 0.95008010 |
79 | MP0003329_amyloid_beta_deposits | 0.92537862 |
80 | MP0002837_dystrophic_cardiac_calcinosis | 0.91944826 |
81 | MP0005319_abnormal_enzyme/_coenzyme | 0.91808538 |
82 | MP0000920_abnormal_myelination | 0.90479663 |
83 | MP0002254_reproductive_system_inflammat | 0.89952473 |
84 | MP0004782_abnormal_surfactant_physiolog | 0.89090316 |
85 | MP0001663_abnormal_digestive_system | 0.88957736 |
86 | MP0000249_abnormal_blood_vessel | 0.88533181 |
87 | MP0003186_abnormal_redox_activity | 0.86573317 |
88 | MP0009278_abnormal_bone_marrow | 0.85081525 |
89 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.83585486 |
90 | MP0001851_eye_inflammation | 0.83559521 |
91 | MP0004883_abnormal_blood_vessel | 0.81907360 |
92 | MP0003183_abnormal_peptide_metabolism | 0.81284248 |
93 | MP0008260_abnormal_autophagy | 0.81016557 |
94 | MP0009643_abnormal_urine_homeostasis | 0.80532329 |
95 | MP0003656_abnormal_erythrocyte_physiolo | 0.77769439 |
96 | MP0002398_abnormal_bone_marrow | 0.77422459 |
97 | MP0002429_abnormal_blood_cell | 0.76963252 |
98 | MP0010307_abnormal_tumor_latency | 0.76898631 |
99 | MP0002166_altered_tumor_susceptibility | 0.76375524 |
100 | MP0005647_abnormal_sex_gland | 0.75887196 |
101 | MP0003634_abnormal_glial_cell | 0.75796462 |
102 | MP0005165_increased_susceptibility_to | 0.75604795 |
103 | MP0005167_abnormal_blood-brain_barrier | 0.74271757 |
104 | MP0000598_abnormal_liver_morphology | 0.73008912 |
105 | MP0002090_abnormal_vision | 0.72742241 |
106 | MP0009115_abnormal_fat_cell | 0.72417409 |
107 | MP0002722_abnormal_immune_system | 0.72405903 |
108 | MP0002136_abnormal_kidney_physiology | 0.72275085 |
109 | MP0000858_altered_metastatic_potential | 0.71800297 |
110 | MP0002933_joint_inflammation | 0.71419543 |
111 | MP0001727_abnormal_embryo_implantation | 0.71265466 |
112 | MP0005023_abnormal_wound_healing | 0.71141329 |
113 | MP0005334_abnormal_fat_pad | 0.71082002 |
114 | MP0005595_abnormal_vascular_smooth | 0.70937404 |
115 | MP0002138_abnormal_hepatobiliary_system | 0.70139582 |
116 | MP0003795_abnormal_bone_structure | 0.69641178 |
117 | MP0003091_abnormal_cell_migration | 0.69562530 |
118 | MP0001756_abnormal_urination | 0.68220286 |
119 | MP0003646_muscle_fatigue | 0.67074466 |
120 | MP0008874_decreased_physiological_sensi | 0.67015848 |
121 | MP0003279_aneurysm | 0.65718281 |
122 | MP0001501_abnormal_sleep_pattern | 0.65412357 |
123 | MP0005666_abnormal_adipose_tissue | 0.62865970 |
124 | MP0003879_abnormal_hair_cell | 0.62198513 |
125 | MP0009765_abnormal_xenobiotic_induced | 0.60705102 |
126 | MP0005535_abnormal_body_temperature | 0.57498868 |
127 | MP0001873_stomach_inflammation | 0.56091188 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Glomerulonephritis (HP:0000099) | 7.58674595 |
2 | Complement deficiency (HP:0004431) | 7.20935287 |
3 | Abnormality of complement system (HP:0005339) | 6.48948777 |
4 | Increased cerebral lipofuscin (HP:0011813) | 6.39228908 |
5 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 6.08033474 |
6 | Vacuolated lymphocytes (HP:0001922) | 5.79923974 |
7 | Recurrent abscess formation (HP:0002722) | 5.37968484 |
8 | Recurrent bacterial skin infections (HP:0005406) | 5.04979199 |
9 | Dysostosis multiplex (HP:0000943) | 4.55667786 |
10 | Eczematoid dermatitis (HP:0000976) | 4.41431677 |
11 | Axonal loss (HP:0003447) | 4.41085715 |
12 | Nephritis (HP:0000123) | 4.35577173 |
13 | Nuclear cataract (HP:0100018) | 4.31380078 |
14 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.26739617 |
15 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 4.24994272 |
16 | Disinhibition (HP:0000734) | 4.07797095 |
17 | Urinary glycosaminoglycan excretion (HP:0003541) | 3.65667952 |
18 | Mucopolysacchariduria (HP:0008155) | 3.65667952 |
19 | Spontaneous hematomas (HP:0007420) | 3.51712019 |
20 | Autoimmune thrombocytopenia (HP:0001973) | 3.50764585 |
21 | Abnormality of polysaccharide metabolism (HP:0011012) | 3.38288676 |
22 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 3.38288676 |
23 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 3.38288676 |
24 | Thick nail (HP:0001805) | 3.34514860 |
25 | Joint hemorrhage (HP:0005261) | 3.34210495 |
26 | Abnormality of macrophages (HP:0004311) | 3.32071987 |
27 | Myocardial infarction (HP:0001658) | 3.31709424 |
28 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 3.02257723 |
29 | Xanthomatosis (HP:0000991) | 2.95177462 |
30 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.95067157 |
31 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.95067157 |
32 | Abnormality of glycolipid metabolism (HP:0010969) | 2.95067157 |
33 | Purpura (HP:0000979) | 2.89081858 |
34 | Upper motor neuron abnormality (HP:0002127) | 2.87777647 |
35 | Agnosia (HP:0010524) | 2.68202685 |
36 | Neurofibrillary tangles (HP:0002185) | 2.67223461 |
37 | Recurrent skin infections (HP:0001581) | 2.63344537 |
38 | Progressive neurologic deterioration (HP:0002344) | 2.62014584 |
39 | Progressive visual loss (HP:0000529) | 2.61726707 |
40 | Gingivitis (HP:0000230) | 2.57811952 |
41 | Pustule (HP:0200039) | 2.55818720 |
42 | Mutism (HP:0002300) | 2.54201462 |
43 | Chronic obstructive pulmonary disease (HP:0006510) | 2.50762055 |
44 | Obstructive lung disease (HP:0006536) | 2.50762055 |
45 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.49991843 |
46 | Osteolytic defects of the hand bones (HP:0009699) | 2.49991843 |
47 | Myositis (HP:0100614) | 2.49190473 |
48 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.48135097 |
49 | Mediastinal lymphadenopathy (HP:0100721) | 2.47405073 |
50 | Orchitis (HP:0100796) | 2.42858106 |
51 | Cellulitis (HP:0100658) | 2.41976844 |
52 | Conjunctival telangiectasia (HP:0000524) | 2.40669677 |
53 | Loss of speech (HP:0002371) | 2.37887426 |
54 | Dementia (HP:0000726) | 2.37443449 |
55 | Chronic otitis media (HP:0000389) | 2.34199744 |
56 | Pathologic fracture (HP:0002756) | 2.31288903 |
57 | Hypercholesterolemia (HP:0003124) | 2.27480841 |
58 | Asymmetric septal hypertrophy (HP:0001670) | 2.26446375 |
59 | Prostate neoplasm (HP:0100787) | 2.26276479 |
60 | J-shaped sella turcica (HP:0002680) | 2.24543005 |
61 | Hepatosplenomegaly (HP:0001433) | 2.21934560 |
62 | Peripheral demyelination (HP:0011096) | 2.20878387 |
63 | Polyneuropathy (HP:0001271) | 2.19878677 |
64 | Metaphyseal irregularity (HP:0003025) | 2.18756179 |
65 | Keratoconjunctivitis sicca (HP:0001097) | 2.18552061 |
66 | Abnormality of the lumbar spine (HP:0100712) | 2.17684256 |
67 | Hyperlipoproteinemia (HP:0010980) | 2.15522405 |
68 | Petechiae (HP:0000967) | 2.15368058 |
69 | Personality changes (HP:0000751) | 2.12274231 |
70 | Memory impairment (HP:0002354) | 2.11132982 |
71 | Urticaria (HP:0001025) | 2.10788688 |
72 | Cerebral inclusion bodies (HP:0100314) | 2.09453713 |
73 | Deep venous thrombosis (HP:0002625) | 2.07599745 |
74 | Basal ganglia calcification (HP:0002135) | 2.06612907 |
75 | Abnormality of the common coagulation pathway (HP:0010990) | 2.04926035 |
76 | Supranuclear gaze palsy (HP:0000605) | 2.04728070 |
77 | Skin nodule (HP:0200036) | 2.04667506 |
78 | Inappropriate behavior (HP:0000719) | 2.01562236 |
79 | Systemic lupus erythematosus (HP:0002725) | 10.1442355 |
80 | Abnormality of the prostate (HP:0008775) | 1.99139666 |
81 | Hemoptysis (HP:0002105) | 1.99102370 |
82 | Retinal atrophy (HP:0001105) | 1.98850390 |
83 | Keratoconjunctivitis (HP:0001096) | 1.97113217 |
84 | Bone pain (HP:0002653) | 1.95707875 |
85 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.95032073 |
86 | Retrobulbar optic neuritis (HP:0100654) | 1.94845355 |
87 | Optic neuritis (HP:0100653) | 1.94845355 |
88 | Recurrent viral infections (HP:0004429) | 1.94010028 |
89 | Interstitial pulmonary disease (HP:0006530) | 1.92894442 |
90 | Vasculitis (HP:0002633) | 1.91111992 |
91 | Cardiomegaly (HP:0001640) | 1.89973697 |
92 | Vertebral compression fractures (HP:0002953) | 1.88379512 |
93 | Amyloidosis (HP:0011034) | 1.87484038 |
94 | Beaking of vertebral bodies (HP:0004568) | 1.86113593 |
95 | Increased IgM level (HP:0003496) | 1.85415634 |
96 | Abnormality of iron homeostasis (HP:0011031) | 1.85306741 |
97 | Nausea (HP:0002018) | 1.84938672 |
98 | Apathy (HP:0000741) | 1.83858877 |
99 | Thoracic kyphosis (HP:0002942) | 1.83829316 |
100 | Hypoalphalipoproteinemia (HP:0003233) | 1.83791475 |
101 | Acrocyanosis (HP:0001063) | 1.83256907 |
102 | Zonular cataract (HP:0010920) | 1.83176300 |
103 | Abnormality of the basal ganglia (HP:0002134) | 1.82801896 |
104 | Abnormality of the nasal mucosa (HP:0000433) | 1.82530268 |
105 | Hematochezia (HP:0002573) | 1.82245520 |
106 | Abnormality of lateral ventricle (HP:0030047) | 1.81742799 |
107 | Diminished motivation (HP:0000745) | 1.78771213 |
108 | Malnutrition (HP:0004395) | 1.77785997 |
109 | Periodontitis (HP:0000704) | 1.77499316 |
110 | Gangrene (HP:0100758) | 1.77017032 |
111 | Increased serum ferritin (HP:0003281) | 1.75020850 |
112 | Epidermoid cyst (HP:0200040) | 1.73116797 |
113 | Frequent falls (HP:0002359) | 1.72967885 |
114 | Neuronal loss in central nervous system (HP:0002529) | 1.71752703 |
115 | Pulmonary infiltrates (HP:0002113) | 1.70206454 |
116 | Prolonged neonatal jaundice (HP:0006579) | 1.69737766 |
117 | Bone cyst (HP:0012062) | 1.69726590 |
118 | Osteomyelitis (HP:0002754) | 1.69049168 |
119 | Recurrent pneumonia (HP:0006532) | 1.68678915 |
120 | Anorexia (HP:0002039) | 1.68564753 |
121 | Urinary incontinence (HP:0000020) | 1.67313775 |
122 | Recurrent fungal infections (HP:0002841) | 1.66826656 |
123 | Gingival bleeding (HP:0000225) | 1.66702248 |
124 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.66562436 |
125 | Meningitis (HP:0001287) | 1.65853229 |
126 | Global brain atrophy (HP:0002283) | 1.65798512 |
127 | Restrictive lung disease (HP:0002091) | 1.65391678 |
128 | Esophageal varix (HP:0002040) | 1.65349871 |
129 | Mucosal telangiectasiae (HP:0100579) | 1.65076653 |
130 | Disproportionate tall stature (HP:0001519) | 1.63639144 |
131 | Stomatitis (HP:0010280) | 1.63246270 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BLK | 5.46717304 |
2 | IRAK4 | 3.57222871 |
3 | TYK2 | 3.31896034 |
4 | TGFBR2 | 3.14268799 |
5 | TAOK2 | 3.00014661 |
6 | ERN1 | 2.98581913 |
7 | TBK1 | 2.98347761 |
8 | DDR2 | 2.81228343 |
9 | MAP3K14 | 2.80758400 |
10 | MAP3K11 | 2.75144924 |
11 | CAMK1D | 2.58148642 |
12 | EPHB1 | 2.48848879 |
13 | GRK7 | 2.48377674 |
14 | TAOK1 | 2.43760079 |
15 | IKBKE | 2.38332098 |
16 | KIT | 2.31875755 |
17 | BTK | 2.25025216 |
18 | RIPK4 | 1.96916222 |
19 | CSF1R | 1.92457494 |
20 | IRAK3 | 1.90639651 |
21 | CSK | 1.82958129 |
22 | JAK1 | 1.78402566 |
23 | ACVR1B | 1.72895493 |
24 | CAMK1G | 1.70308147 |
25 | HCK | 1.70273595 |
26 | FES | 1.69183339 |
27 | MAP4K1 | 1.67541591 |
28 | ZAP70 | 1.65502219 |
29 | IKBKB | 1.60333093 |
30 | LYN | 1.47341288 |
31 | TTN | 1.46750661 |
32 | PRPF4B | 1.45821614 |
33 | NEK9 | 1.37886293 |
34 | CDC42BPA | 1.36917174 |
35 | TRIB3 | 1.35219106 |
36 | SCYL2 | 1.34036921 |
37 | TAOK3 | 1.33081319 |
38 | SYK | 1.29265198 |
39 | CAMKK2 | 1.28980637 |
40 | BMX | 1.28708443 |
41 | FGR | 1.26281179 |
42 | FGFR4 | 1.23674562 |
43 | TXK | 1.20519015 |
44 | ADRBK2 | 1.13616352 |
45 | TEC | 1.13008106 |
46 | CDK6 | 1.08418729 |
47 | JAK2 | 1.06854600 |
48 | TESK1 | 1.06439643 |
49 | TESK2 | 1.06366363 |
50 | MAP3K5 | 1.06141787 |
51 | LCK | 1.05689643 |
52 | ABL2 | 1.05056044 |
53 | ITK | 1.03113897 |
54 | YES1 | 0.98831706 |
55 | DMPK | 0.94247361 |
56 | MAP3K13 | 0.90842895 |
57 | CAMKK1 | 0.89739313 |
58 | EPHB2 | 0.88988006 |
59 | EGFR | 0.83299794 |
60 | PKN2 | 0.79682782 |
61 | PIM2 | 0.77303959 |
62 | MAP2K6 | 0.76585359 |
63 | IRAK1 | 0.76178991 |
64 | CHUK | 0.75812141 |
65 | ABL1 | 0.75543420 |
66 | PIK3CG | 0.74758560 |
67 | SIK3 | 0.73922519 |
68 | TYRO3 | 0.73540574 |
69 | MAP3K3 | 0.72986821 |
70 | MARK3 | 0.72887427 |
71 | STK10 | 0.72542119 |
72 | TGFBR1 | 0.71850031 |
73 | NME2 | 0.68720376 |
74 | IRAK2 | 0.68611462 |
75 | BMPR2 | 0.67570244 |
76 | SIK1 | 0.66804333 |
77 | PTK6 | 0.65999603 |
78 | PTK2B | 0.65142977 |
79 | PRKCD | 0.64905290 |
80 | KDR | 0.63501316 |
81 | EPHA3 | 0.62708171 |
82 | MATK | 0.62231601 |
83 | MAP2K3 | 0.60447174 |
84 | PDGFRA | 0.59524409 |
85 | PAK4 | 0.57757931 |
86 | ICK | 0.57255579 |
87 | PDGFRB | 0.56672487 |
88 | GSK3A | 0.56579585 |
89 | PKN1 | 0.56529444 |
90 | DAPK3 | 0.56038529 |
91 | FGFR3 | 0.55822560 |
92 | DAPK2 | 0.53662741 |
93 | PIM1 | 0.53386891 |
94 | TNK2 | 0.53216628 |
95 | ARAF | 0.53167739 |
96 | JAK3 | 0.52569856 |
97 | BCKDK | 0.52312178 |
98 | IGF1R | 0.51803364 |
99 | MAP2K2 | 0.51141812 |
100 | MOS | 0.49389954 |
101 | FYN | 0.47595514 |
102 | EIF2AK2 | 0.44982324 |
103 | RIPK1 | 0.44124565 |
104 | DYRK3 | 0.44100523 |
105 | RPS6KL1 | 0.40452759 |
106 | RPS6KC1 | 0.40452759 |
107 | MAPK4 | 0.39973396 |
108 | LRRK2 | 0.39331510 |
109 | LATS2 | 0.38675188 |
110 | SRC | 0.38622324 |
111 | MAPK7 | 0.36515055 |
112 | STK24 | 0.35658175 |
113 | MAPKAPK2 | 0.34732958 |
114 | PBK | 0.32084989 |
115 | RPS6KA6 | 0.30846703 |
116 | GRK6 | 0.30003889 |
117 | MET | 0.28941997 |
118 | SIK2 | 0.28302742 |
119 | CLK1 | 0.27751329 |
120 | MAPK11 | 0.27475740 |
121 | PRKD1 | 0.27325912 |
122 | PDPK1 | 0.27132040 |
123 | PRKCG | 0.26755277 |
124 | MST1R | 0.26470061 |
125 | MAP3K2 | 0.25809922 |
126 | DYRK1B | 0.25277819 |
127 | INSR | 0.25098653 |
128 | PRKACG | 0.25000059 |
129 | MAPK12 | 0.24351020 |
130 | HIPK2 | 0.23720132 |
131 | MAP3K1 | 0.23707917 |
132 | STK3 | 0.23051862 |
133 | MARK2 | 0.22347008 |
134 | PRKAA2 | 0.22319681 |
135 | RPS6KA2 | 0.22157154 |
136 | PRKG2 | 0.21477067 |
137 | CDK4 | 0.19838527 |
138 | PDK1 | 0.18716637 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 6.52458036 |
2 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 3.37039049 |
3 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 3.15650232 |
4 | Lysosome_Homo sapiens_hsa04142 | 3.09337429 |
5 | Leishmaniasis_Homo sapiens_hsa05140 | 2.58053303 |
6 | Pertussis_Homo sapiens_hsa05133 | 2.56555859 |
7 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.28880832 |
8 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.27445588 |
9 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.20118885 |
10 | Other glycan degradation_Homo sapiens_hsa00511 | 2.06510459 |
11 | Malaria_Homo sapiens_hsa05144 | 1.86993020 |
12 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.84504835 |
13 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.83141958 |
14 | Tuberculosis_Homo sapiens_hsa05152 | 1.78051407 |
15 | Prion diseases_Homo sapiens_hsa05020 | 1.73203604 |
16 | Phagosome_Homo sapiens_hsa04145 | 1.64691819 |
17 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.61292500 |
18 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.60507085 |
19 | Legionellosis_Homo sapiens_hsa05134 | 1.58528791 |
20 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.51317315 |
21 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.47015636 |
22 | Salmonella infection_Homo sapiens_hsa05132 | 1.41098772 |
23 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.37617623 |
24 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.36548132 |
25 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.32183812 |
26 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.26818590 |
27 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.23735737 |
28 | Measles_Homo sapiens_hsa05162 | 1.23551363 |
29 | Asthma_Homo sapiens_hsa05310 | 1.18549136 |
30 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.15543547 |
31 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.15199027 |
32 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.14728478 |
33 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.08850120 |
34 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.08135021 |
35 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.07326989 |
36 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.03455599 |
37 | ABC transporters_Homo sapiens_hsa02010 | 1.01819159 |
38 | Amoebiasis_Homo sapiens_hsa05146 | 1.01205502 |
39 | Influenza A_Homo sapiens_hsa05164 | 0.97137985 |
40 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.97092099 |
41 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.95227024 |
42 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.93193483 |
43 | Shigellosis_Homo sapiens_hsa05131 | 0.92026816 |
44 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.91146671 |
45 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.88577474 |
46 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.87813359 |
47 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.85865909 |
48 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.84170077 |
49 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.79751384 |
50 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.78536863 |
51 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.77473595 |
52 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.77155668 |
53 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.76739609 |
54 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.76378412 |
55 | Bladder cancer_Homo sapiens_hsa05219 | 0.76074976 |
56 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.74883242 |
57 | Apoptosis_Homo sapiens_hsa04210 | 0.74649627 |
58 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.73971194 |
59 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.66096224 |
60 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.65424566 |
61 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.65217674 |
62 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.65044265 |
63 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.64362074 |
64 | Hepatitis C_Homo sapiens_hsa05160 | 0.63979479 |
65 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.63805329 |
66 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.63357701 |
67 | Peroxisome_Homo sapiens_hsa04146 | 0.63279701 |
68 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.63049438 |
69 | Allograft rejection_Homo sapiens_hsa05330 | 0.62467611 |
70 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.62176449 |
71 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.60473352 |
72 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.60189051 |
73 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.59103374 |
74 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.56607541 |
75 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.56574245 |
76 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.56411418 |
77 | Histidine metabolism_Homo sapiens_hsa00340 | 0.56103391 |
78 | Retinol metabolism_Homo sapiens_hsa00830 | 0.56006044 |
79 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.55729187 |
80 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.54977445 |
81 | Platelet activation_Homo sapiens_hsa04611 | 0.54913590 |
82 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.54164356 |
83 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.54131279 |
84 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.53425921 |
85 | Mineral absorption_Homo sapiens_hsa04978 | 0.53286760 |
86 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.53158966 |
87 | * Endocytosis_Homo sapiens_hsa04144 | 0.52250164 |
88 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.51910122 |
89 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.51122670 |
90 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.50828577 |
91 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.50031772 |
92 | Viral myocarditis_Homo sapiens_hsa05416 | 0.49747735 |
93 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.49650918 |
94 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.49315129 |
95 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.48267480 |
96 | Hepatitis B_Homo sapiens_hsa05161 | 0.47732542 |
97 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.47508444 |
98 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.47069668 |
99 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.45738299 |
100 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.45657880 |
101 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.43900253 |
102 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.43868719 |
103 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.43728529 |
104 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.43117287 |
105 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.41940864 |
106 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.41144362 |
107 | Galactose metabolism_Homo sapiens_hsa00052 | 0.41122274 |
108 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.40787896 |
109 | Insulin resistance_Homo sapiens_hsa04931 | 0.39472707 |
110 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.38976738 |
111 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.37614779 |
112 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.35824585 |
113 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.35448174 |
114 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.35139758 |
115 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.34557896 |
116 | HTLV-I infection_Homo sapiens_hsa05166 | 0.33666297 |
117 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.33191897 |
118 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.32592364 |
119 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.29405884 |
120 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.28623429 |
121 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.25333983 |
122 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.22763493 |
123 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.19337974 |
124 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.13985154 |
125 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.12017161 |
126 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.08439590 |
127 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.06140787 |
128 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.06055907 |
129 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.05409782 |