Rank | Gene Set | Z-score |
---|---|---|
1 | proline biosynthetic process (GO:0006561) | 6.05375642 |
2 | regulation of gene silencing by RNA (GO:0060966) | 5.95676152 |
3 | regulation of posttranscriptional gene silencing (GO:0060147) | 5.95676152 |
4 | regulation of gene silencing by miRNA (GO:0060964) | 5.95676152 |
5 | transcription from mitochondrial promoter (GO:0006390) | 5.75061959 |
6 | establishment of apical/basal cell polarity (GO:0035089) | 5.22205616 |
7 | replication fork processing (GO:0031297) | 5.06274365 |
8 | embryonic process involved in female pregnancy (GO:0060136) | 5.02912448 |
9 | histone H4-K12 acetylation (GO:0043983) | 4.95423061 |
10 | establishment of integrated proviral latency (GO:0075713) | 4.93093720 |
11 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 4.84345100 |
12 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 4.84345100 |
13 | protein complex localization (GO:0031503) | 4.76551018 |
14 | L-serine metabolic process (GO:0006563) | 4.64098604 |
15 | formation of translation preinitiation complex (GO:0001731) | 4.60050978 |
16 | establishment of monopolar cell polarity (GO:0061162) | 4.51137577 |
17 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 4.51137577 |
18 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 4.49273226 |
19 | mitochondrial DNA metabolic process (GO:0032042) | 4.41483450 |
20 | proline metabolic process (GO:0006560) | 4.28063476 |
21 | pre-miRNA processing (GO:0031054) | 4.24002009 |
22 | heterochromatin organization (GO:0070828) | 4.17941886 |
23 | mitotic sister chromatid segregation (GO:0000070) | 4.17191134 |
24 | chromatin remodeling at centromere (GO:0031055) | 4.16416822 |
25 | regulation of translational fidelity (GO:0006450) | 4.09869534 |
26 | protein localization to kinetochore (GO:0034501) | 4.07535815 |
27 | negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147) | 4.01812515 |
28 | CENP-A containing nucleosome assembly (GO:0034080) | 4.00455638 |
29 | DNA deamination (GO:0045006) | 3.97862247 |
30 | positive regulation of protein homooligomerization (GO:0032464) | 3.95504496 |
31 | cellular protein complex localization (GO:0034629) | 3.87555854 |
32 | anterior/posterior axis specification, embryo (GO:0008595) | 3.86481728 |
33 | regulation of hippo signaling (GO:0035330) | 3.82053125 |
34 | regulation of integrin activation (GO:0033623) | 3.81956559 |
35 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.80667844 |
36 | DNA strand renaturation (GO:0000733) | 3.68577049 |
37 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.68532024 |
38 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.68532024 |
39 | mitotic metaphase plate congression (GO:0007080) | 3.67872574 |
40 | DNA replication-independent nucleosome organization (GO:0034724) | 3.65185342 |
41 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.65185342 |
42 | establishment of viral latency (GO:0019043) | 3.63155089 |
43 | histone H4-K5 acetylation (GO:0043981) | 3.62967665 |
44 | histone H4-K8 acetylation (GO:0043982) | 3.62967665 |
45 | determination of adult lifespan (GO:0008340) | 3.59492928 |
46 | mitotic G1 DNA damage checkpoint (GO:0031571) | 3.59412328 |
47 | IMP biosynthetic process (GO:0006188) | 3.58977135 |
48 | histone exchange (GO:0043486) | 3.57968633 |
49 | histone arginine methylation (GO:0034969) | 3.53588327 |
50 | nodal signaling pathway (GO:0038092) | 3.53578341 |
51 | positive regulation of developmental pigmentation (GO:0048087) | 3.53351559 |
52 | paraxial mesoderm development (GO:0048339) | 3.50271632 |
53 | negative regulation of telomerase activity (GO:0051974) | 3.50045459 |
54 | sister chromatid segregation (GO:0000819) | 3.49870038 |
55 | ribosome biogenesis (GO:0042254) | 3.46752954 |
56 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.46513752 |
57 | negative regulation of chromosome segregation (GO:0051985) | 3.39731828 |
58 | ribosomal small subunit biogenesis (GO:0042274) | 3.39705517 |
59 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.37307906 |
60 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.37307906 |
61 | negative regulation of sister chromatid segregation (GO:0033046) | 3.37307906 |
62 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.37307906 |
63 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.37307906 |
64 | notochord development (GO:0030903) | 3.36157750 |
65 | IMP metabolic process (GO:0046040) | 3.34960935 |
66 | regulation of double-strand break repair (GO:2000779) | 3.34328275 |
67 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.33655415 |
68 | regulation of telomere maintenance via telomerase (GO:0032210) | 3.33303373 |
69 | DNA unwinding involved in DNA replication (GO:0006268) | 3.31958274 |
70 | regulation of protein homooligomerization (GO:0032462) | 3.30646936 |
71 | DNA duplex unwinding (GO:0032508) | 3.29030939 |
72 | negative regulation of cell cycle arrest (GO:0071157) | 3.29019084 |
73 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.28992685 |
74 | DNA geometric change (GO:0032392) | 3.27736847 |
75 | regulation of gene silencing (GO:0060968) | 3.27693768 |
76 | somite rostral/caudal axis specification (GO:0032525) | 3.26422738 |
77 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.25075374 |
78 | viral mRNA export from host cell nucleus (GO:0046784) | 3.25026949 |
79 | apoptotic process involved in morphogenesis (GO:0060561) | 3.24887729 |
80 | mRNA cleavage (GO:0006379) | 3.24802723 |
81 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.23341327 |
82 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.23341327 |
83 | intracellular estrogen receptor signaling pathway (GO:0030520) | 3.22254262 |
84 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.19053677 |
85 | regulation of cell fate specification (GO:0042659) | 3.18633384 |
86 | purine nucleobase biosynthetic process (GO:0009113) | 3.18278621 |
87 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.18204169 |
88 | chromatin assembly (GO:0031497) | 3.18050365 |
89 | regulation of intracellular estrogen receptor signaling pathway (GO:0033146) | 3.16532671 |
90 | base-excision repair (GO:0006284) | 3.16435980 |
91 | mitotic G1/S transition checkpoint (GO:0044819) | 3.15992481 |
92 | ATP-dependent chromatin remodeling (GO:0043044) | 3.15589993 |
93 | nuclear pore organization (GO:0006999) | 3.15457811 |
94 | chromatin assembly or disassembly (GO:0006333) | 3.13840877 |
95 | rRNA transcription (GO:0009303) | 3.13719081 |
96 | ribosome assembly (GO:0042255) | 3.13477117 |
97 | serine family amino acid biosynthetic process (GO:0009070) | 3.13377579 |
98 | termination of RNA polymerase III transcription (GO:0006386) | 3.13032981 |
99 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.13032981 |
100 | maturation of SSU-rRNA (GO:0030490) | 3.12345990 |
101 | regulation of sister chromatid cohesion (GO:0007063) | 3.11749572 |
102 | spindle checkpoint (GO:0031577) | 3.10784923 |
103 | ribosomal small subunit assembly (GO:0000028) | 3.08165182 |
104 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 3.08064803 |
105 | G1 DNA damage checkpoint (GO:0044783) | 3.07602256 |
106 | negative regulation of androgen receptor signaling pathway (GO:0060766) | 3.06948634 |
107 | DNA replication initiation (GO:0006270) | 3.04061330 |
108 | negative regulation of mRNA processing (GO:0050686) | 3.03557325 |
109 | mitotic spindle checkpoint (GO:0071174) | 3.03475977 |
110 | regulation of chromosome segregation (GO:0051983) | 3.03425026 |
111 | nucleobase biosynthetic process (GO:0046112) | 3.03254032 |
112 | mitochondrial RNA metabolic process (GO:0000959) | 3.02970473 |
113 | embryonic camera-type eye development (GO:0031076) | 3.01570699 |
114 | nuclear pore complex assembly (GO:0051292) | 3.01531700 |
115 | cullin deneddylation (GO:0010388) | 3.01355066 |
116 | lung-associated mesenchyme development (GO:0060484) | 3.01126183 |
117 | mitotic nuclear envelope disassembly (GO:0007077) | 3.00705222 |
118 | protein localization to chromosome, centromeric region (GO:0071459) | 3.00699472 |
119 | mitotic chromosome condensation (GO:0007076) | 3.00656018 |
120 | polarized epithelial cell differentiation (GO:0030859) | 2.99709479 |
121 | mitochondrial DNA replication (GO:0006264) | 2.99653411 |
122 | termination of RNA polymerase II transcription (GO:0006369) | 2.99338667 |
123 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 2.98710491 |
124 | DNA strand elongation (GO:0022616) | 2.98557369 |
125 | pseudouridine synthesis (GO:0001522) | 2.98159274 |
126 | muscle organ morphogenesis (GO:0048644) | 2.97422671 |
127 | regulation of helicase activity (GO:0051095) | 2.96904130 |
128 | viral transcription (GO:0019083) | 2.96808934 |
129 | negative regulation of gene silencing (GO:0060969) | 2.96681050 |
130 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 2.95842650 |
131 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 2.95842650 |
132 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 2.95842650 |
133 | oxidative demethylation (GO:0070989) | 2.95813817 |
134 | chaperone-mediated protein transport (GO:0072321) | 2.94969920 |
135 | spindle assembly (GO:0051225) | 2.93727535 |
136 | translational termination (GO:0006415) | 2.93284898 |
137 | DNA replication checkpoint (GO:0000076) | 2.93152470 |
138 | peptidyl-arginine omega-N-methylation (GO:0035247) | 2.92928047 |
139 | negative regulation of RNA splicing (GO:0033119) | 2.92912041 |
140 | poly(A)+ mRNA export from nucleus (GO:0016973) | 2.92157653 |
141 | mitotic spindle assembly checkpoint (GO:0007094) | 2.92067400 |
142 | regulation of histone H3-K9 methylation (GO:0051570) | 2.90791306 |
143 | positive regulation of chromosome segregation (GO:0051984) | 2.89841394 |
144 | negative regulation of histone methylation (GO:0031061) | 2.89488717 |
145 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.87648811 |
146 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 2.87607235 |
147 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.86781061 |
148 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.86476007 |
149 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.86476007 |
150 | regulation of sister chromatid segregation (GO:0033045) | 2.85235828 |
151 | regulation of mitotic sister chromatid separation (GO:0010965) | 2.85235828 |
152 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.85235828 |
153 | L-alpha-amino acid transmembrane transport (GO:1902475) | 2.85184469 |
154 | spindle assembly checkpoint (GO:0071173) | 2.84586616 |
155 | metaphase plate congression (GO:0051310) | 2.84567797 |
156 | spliceosomal snRNP assembly (GO:0000387) | 2.83316356 |
157 | DNA damage response, detection of DNA damage (GO:0042769) | 2.82490601 |
158 | negative regulation of mitosis (GO:0045839) | 2.81947296 |
159 | regulation of stem cell maintenance (GO:2000036) | 2.78296047 |
160 | mitotic sister chromatid cohesion (GO:0007064) | 2.77472451 |
161 | telomere maintenance via telomerase (GO:0007004) | 2.74993766 |
162 | nucleosome disassembly (GO:0006337) | 2.74386119 |
163 | protein-DNA complex disassembly (GO:0032986) | 2.74386119 |
164 | telomere maintenance via recombination (GO:0000722) | 2.74147252 |
165 | kinetochore organization (GO:0051383) | 2.73767921 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 5.22707453 |
2 | * KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 4.25021171 |
3 | * KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 4.25021171 |
4 | * KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 4.25021171 |
5 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 3.73876491 |
6 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.26236065 |
7 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 3.00418492 |
8 | * NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 3.00239041 |
9 | * POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 2.98671447 |
10 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.98350255 |
11 | * ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 2.91619434 |
12 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 2.89185658 |
13 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.81076814 |
14 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.76587664 |
15 | * SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 2.75077492 |
16 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 2.60282984 |
17 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 2.58549833 |
18 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 2.31563689 |
19 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.28635241 |
20 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.25162699 |
21 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.24016342 |
22 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 2.18626055 |
23 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.18393819 |
24 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 2.16220588 |
25 | * KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 2.15410394 |
26 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.13784239 |
27 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 2.12582549 |
28 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.11924504 |
29 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.10745518 |
30 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 2.08497081 |
31 | * SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 2.05772934 |
32 | * NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.98111251 |
33 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 1.96216805 |
34 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.96105259 |
35 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.95394772 |
36 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 1.94300841 |
37 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.89140208 |
38 | * SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.89004843 |
39 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.85702686 |
40 | * POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.83965530 |
41 | * NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.81638885 |
42 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.76366948 |
43 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.74734139 |
44 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.74493763 |
45 | * MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.64529751 |
46 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.62521736 |
47 | SOX2_18692474_ChIP-Seq_MESCs_Mouse | 1.55848288 |
48 | NANOG_18692474_ChIP-Seq_MESCs_Mouse | 1.54995079 |
49 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 1.54396215 |
50 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.54216392 |
51 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.53721729 |
52 | POU5F1_18692474_ChIP-Seq_MESCs_Mouse | 1.52758206 |
53 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.51446804 |
54 | MYC_22102868_ChIP-Seq_BL_Human | 1.49164168 |
55 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.48012490 |
56 | * ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.47893010 |
57 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.47293444 |
58 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.46975168 |
59 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.46839043 |
60 | NANOG_18692474_ChIP-Seq_MEFs_Mouse | 1.45907282 |
61 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.45535154 |
62 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.43618814 |
63 | * TCF3_18347094_ChIP-ChIP_MESCs_Mouse | 1.43189050 |
64 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.41483014 |
65 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.40993202 |
66 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.40205781 |
67 | * ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.37388191 |
68 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.36358510 |
69 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.34747592 |
70 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.33707543 |
71 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.33464219 |
72 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.32926659 |
73 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.32674645 |
74 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.32330812 |
75 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.32171467 |
76 | * PRDM14_21183938_ChIP-Seq_MESCs_Mouse | 1.30853795 |
77 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.28915061 |
78 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.28209230 |
79 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.26821842 |
80 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.26238844 |
81 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.25226421 |
82 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.24226612 |
83 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.21866280 |
84 | * NANOG_16518401_ChIP-PET_MESCs_Mouse | 1.15017806 |
85 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.14295561 |
86 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.14112913 |
87 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.12956691 |
88 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.12611942 |
89 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.10184068 |
90 | KAP1_27257070_Chip-Seq_ESCs_Mouse | 1.09880348 |
91 | * POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 1.09835405 |
92 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.09615586 |
93 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.09488512 |
94 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.09191630 |
95 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.08986012 |
96 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.07544708 |
97 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.07248278 |
98 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.06747970 |
99 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.06558721 |
100 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.05004653 |
101 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.03934057 |
102 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.02621872 |
103 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.02330851 |
104 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.02328351 |
105 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.99166295 |
106 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.98549460 |
107 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.97917418 |
108 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.95543808 |
109 | * RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.93900852 |
110 | * LXR_22292898_ChIP-Seq_THP-1_Human | 0.93647121 |
111 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.92741193 |
112 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.92546083 |
113 | SETDB1_19884255_ChIP-Seq_MESCs_Mouse | 0.91015900 |
114 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 0.90536088 |
115 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.90487549 |
116 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.89920178 |
117 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 0.89810525 |
118 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.89407275 |
119 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.89136991 |
120 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 0.89086737 |
121 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.88458236 |
122 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.88148368 |
123 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.88092262 |
124 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.86858640 |
125 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 0.86664789 |
126 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.86366172 |
127 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.85723602 |
128 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.84983279 |
129 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.84668924 |
130 | * CHD1_26751641_Chip-Seq_LNCaP_Human | 0.83943699 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008057_abnormal_DNA_replication | 5.36347228 |
2 | MP0003890_abnormal_embryonic-extraembry | 3.50591614 |
3 | MP0004957_abnormal_blastocyst_morpholog | 3.36488840 |
4 | MP0010030_abnormal_orbit_morphology | 3.28088982 |
5 | MP0002653_abnormal_ependyma_morphology | 3.02237996 |
6 | MP0004133_heterotaxia | 2.86097585 |
7 | MP0010352_gastrointestinal_tract_polyps | 2.76014720 |
8 | MP0010094_abnormal_chromosome_stability | 2.74676263 |
9 | MP0003111_abnormal_nucleus_morphology | 2.57030578 |
10 | MP0003283_abnormal_digestive_organ | 2.48018389 |
11 | MP0009672_abnormal_birth_weight | 2.42094462 |
12 | MP0003119_abnormal_digestive_system | 2.37061542 |
13 | MP0003077_abnormal_cell_cycle | 2.29278358 |
14 | MP0003693_abnormal_embryo_hatching | 2.18198737 |
15 | MP0001188_hyperpigmentation | 2.16343992 |
16 | MP0001293_anophthalmia | 2.14789362 |
17 | MP0009278_abnormal_bone_marrow | 2.10280570 |
18 | MP0006292_abnormal_olfactory_placode | 2.08354883 |
19 | MP0004264_abnormal_extraembryonic_tissu | 2.06583451 |
20 | MP0005171_absent_coat_pigmentation | 2.06433571 |
21 | MP0001672_abnormal_embryogenesis/_devel | 2.00098148 |
22 | MP0005380_embryogenesis_phenotype | 2.00098148 |
23 | * MP0002085_abnormal_embryonic_tissue | 1.96802948 |
24 | * MP0002084_abnormal_developmental_patter | 1.95829403 |
25 | MP0002938_white_spotting | 1.94487187 |
26 | MP0003718_maternal_effect | 1.90372831 |
27 | MP0003136_yellow_coat_color | 1.85665750 |
28 | * MP0002086_abnormal_extraembryonic_tissu | 1.85134448 |
29 | * MP0000350_abnormal_cell_proliferation | 1.80585010 |
30 | MP0001697_abnormal_embryo_size | 1.77993547 |
31 | MP0001730_embryonic_growth_arrest | 1.77481031 |
32 | MP0004197_abnormal_fetal_growth/weight/ | 1.76822328 |
33 | MP0003937_abnormal_limbs/digits/tail_de | 1.75103406 |
34 | MP0008058_abnormal_DNA_repair | 1.74236323 |
35 | * MP0008932_abnormal_embryonic_tissue | 1.69927889 |
36 | MP0003984_embryonic_growth_retardation | 1.68761524 |
37 | MP0002088_abnormal_embryonic_growth/wei | 1.66441029 |
38 | MP0004233_abnormal_muscle_weight | 1.66207615 |
39 | MP0002249_abnormal_larynx_morphology | 1.60733275 |
40 | MP0005076_abnormal_cell_differentiation | 1.56231606 |
41 | MP0003786_premature_aging | 1.53174181 |
42 | MP0008877_abnormal_DNA_methylation | 1.52013742 |
43 | MP0003705_abnormal_hypodermis_morpholog | 1.51570738 |
44 | MP0005075_abnormal_melanosome_morpholog | 1.51225983 |
45 | MP0000537_abnormal_urethra_morphology | 1.49961621 |
46 | MP0002254_reproductive_system_inflammat | 1.45530331 |
47 | MP0005377_hearing/vestibular/ear_phenot | 1.39304474 |
48 | MP0003878_abnormal_ear_physiology | 1.39304474 |
49 | MP0000566_synostosis | 1.38901728 |
50 | MP0000579_abnormal_nail_morphology | 1.38220124 |
51 | MP0003941_abnormal_skin_development | 1.36420928 |
52 | MP0002332_abnormal_exercise_endurance | 1.35125389 |
53 | * MP0002080_prenatal_lethality | 1.34686856 |
54 | MP0000762_abnormal_tongue_morphology | 1.33420783 |
55 | MP0009379_abnormal_foot_pigmentation | 1.31092092 |
56 | MP0002111_abnormal_tail_morphology | 1.26255813 |
57 | MP0001346_abnormal_lacrimal_gland | 1.24988234 |
58 | MP0000490_abnormal_crypts_of | 1.19121379 |
59 | MP0001849_ear_inflammation | 1.17545925 |
60 | MP0002269_muscular_atrophy | 1.15848154 |
61 | MP0002932_abnormal_joint_morphology | 1.15780901 |
62 | MP0005499_abnormal_olfactory_system | 1.15736337 |
63 | MP0005394_taste/olfaction_phenotype | 1.15736337 |
64 | MP0003453_abnormal_keratinocyte_physiol | 1.15113296 |
65 | MP0006072_abnormal_retinal_apoptosis | 1.14583636 |
66 | MP0002009_preneoplasia | 1.10913892 |
67 | MP0001348_abnormal_lacrimal_gland | 1.10824349 |
68 | MP0005266_abnormal_metabolism | 1.10225362 |
69 | MP0003567_abnormal_fetal_cardiomyocyte | 1.09737292 |
70 | MP0000516_abnormal_urinary_system | 1.08715780 |
71 | MP0005367_renal/urinary_system_phenotyp | 1.08715780 |
72 | * MP0000432_abnormal_head_morphology | 1.07482075 |
73 | MP0002114_abnormal_axial_skeleton | 1.06181445 |
74 | MP0002233_abnormal_nose_morphology | 1.05660776 |
75 | MP0008007_abnormal_cellular_replicative | 1.03819868 |
76 | MP0009250_abnormal_appendicular_skeleto | 1.02843512 |
77 | MP0002210_abnormal_sex_determination | 1.02629137 |
78 | MP0000049_abnormal_middle_ear | 1.01262734 |
79 | MP0002092_abnormal_eye_morphology | 1.01260188 |
80 | MP0003123_paternal_imprinting | 1.01199459 |
81 | MP0000678_abnormal_parathyroid_gland | 1.01138555 |
82 | MP0004858_abnormal_nervous_system | 1.00321527 |
83 | MP0004272_abnormal_basement_membrane | 1.00235823 |
84 | * MP0003755_abnormal_palate_morphology | 0.99070493 |
85 | MP0003942_abnormal_urinary_system | 0.98537503 |
86 | MP0003315_abnormal_perineum_morphology | 0.98059586 |
87 | MP0002697_abnormal_eye_size | 0.96935419 |
88 | MP0002796_impaired_skin_barrier | 0.96310200 |
89 | * MP0003935_abnormal_craniofacial_develop | 0.95237304 |
90 | MP0009053_abnormal_anal_canal | 0.95216962 |
91 | MP0003806_abnormal_nucleotide_metabolis | 0.94599389 |
92 | * MP0000313_abnormal_cell_death | 0.94016455 |
93 | MP0003861_abnormal_nervous_system | 0.91190940 |
94 | MP0005623_abnormal_meninges_morphology | 0.89862901 |
95 | MP0006035_abnormal_mitochondrial_morpho | 0.89733283 |
96 | MP0002282_abnormal_trachea_morphology | 0.89389658 |
97 | MP0001299_abnormal_eye_distance/ | 0.89068738 |
98 | MP0010307_abnormal_tumor_latency | 0.87504315 |
99 | MP0002019_abnormal_tumor_incidence | 0.87399122 |
100 | MP0000371_diluted_coat_color | 0.86877604 |
101 | MP0002127_abnormal_cardiovascular_syste | 0.86554444 |
102 | MP0001545_abnormal_hematopoietic_system | 0.85944339 |
103 | MP0005397_hematopoietic_system_phenotyp | 0.85944339 |
104 | MP0003566_abnormal_cell_adhesion | 0.85501940 |
105 | MP0009703_decreased_birth_body | 0.85279838 |
106 | MP0005508_abnormal_skeleton_morphology | 0.84542317 |
107 | MP0003938_abnormal_ear_development | 0.84479550 |
108 | MP0001286_abnormal_eye_development | 0.83330392 |
109 | MP0008770_decreased_survivor_rate | 0.82762476 |
110 | * MP0002116_abnormal_craniofacial_bone | 0.82286885 |
111 | MP0005023_abnormal_wound_healing | 0.81839316 |
112 | MP0003121_genomic_imprinting | 0.80708985 |
113 | MP0001145_abnormal_male_reproductive | 0.80243048 |
114 | MP0002075_abnormal_coat/hair_pigmentati | 0.79192744 |
115 | MP0005501_abnormal_skin_physiology | 0.78863959 |
116 | MP0008995_early_reproductive_senescence | 0.76755906 |
117 | MP0000462_abnormal_digestive_system | 0.76279654 |
118 | MP0000653_abnormal_sex_gland | 0.76063988 |
119 | MP0005391_vision/eye_phenotype | 0.75772829 |
120 | MP0000470_abnormal_stomach_morphology | 0.75520661 |
121 | MP0001929_abnormal_gametogenesis | 0.75178288 |
122 | * MP0002925_abnormal_cardiovascular_devel | 0.75175568 |
123 | MP0002089_abnormal_postnatal_growth/wei | 0.74597349 |
124 | MP0000428_abnormal_craniofacial_morphol | 0.73679745 |
125 | MP0004185_abnormal_adipocyte_glucose | 0.71999845 |
126 | MP0002160_abnormal_reproductive_system | 0.71056205 |
127 | MP0009697_abnormal_copulation | 0.70424582 |
128 | MP0003115_abnormal_respiratory_system | 0.69815396 |
129 | MP0000631_abnormal_neuroendocrine_gland | 0.68997312 |
130 | MP0003186_abnormal_redox_activity | 0.67159757 |
131 | MP0003385_abnormal_body_wall | 0.65822427 |
132 | MP0003698_abnormal_male_reproductive | 0.65797844 |
133 | * MP0002081_perinatal_lethality | 0.65261354 |
134 | MP0002161_abnormal_fertility/fecundity | 0.63803500 |
135 | * MP0002751_abnormal_autonomic_nervous | 0.62229841 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Rib fusion (HP:0000902) | 5.80026293 |
2 | Rectovaginal fistula (HP:0000143) | 4.76293719 |
3 | Rectal fistula (HP:0100590) | 4.76293719 |
4 | Ependymoma (HP:0002888) | 4.36028990 |
5 | Intestinal fistula (HP:0100819) | 4.33202816 |
6 | Aplasia/hypoplasia of the humerus (HP:0006507) | 4.28698749 |
7 | Short humerus (HP:0005792) | 4.24767232 |
8 | Vaginal fistula (HP:0004320) | 4.11212376 |
9 | Hypochromic microcytic anemia (HP:0004840) | 4.10136902 |
10 | Septo-optic dysplasia (HP:0100842) | 3.97732847 |
11 | Birth length less than 3rd percentile (HP:0003561) | 3.77210482 |
12 | Abnormality of the astrocytes (HP:0100707) | 3.74481194 |
13 | Astrocytoma (HP:0009592) | 3.74481194 |
14 | Concave nail (HP:0001598) | 3.69522792 |
15 | Abnormality of the lower motor neuron (HP:0002366) | 3.48612468 |
16 | Absent radius (HP:0003974) | 3.46474333 |
17 | Rhabdomyosarcoma (HP:0002859) | 3.35990550 |
18 | Reticulocytopenia (HP:0001896) | 3.25815775 |
19 | Tongue fasciculations (HP:0001308) | 3.25526325 |
20 | Absent forearm bone (HP:0003953) | 3.24443053 |
21 | Aplasia involving forearm bones (HP:0009822) | 3.24443053 |
22 | Abnormality of the labia minora (HP:0012880) | 3.24353183 |
23 | Facial hemangioma (HP:0000329) | 3.22737464 |
24 | Neoplasm of striated muscle (HP:0009728) | 3.16460901 |
25 | Neoplasm of the oral cavity (HP:0100649) | 3.16212119 |
26 | Selective tooth agenesis (HP:0001592) | 3.10817302 |
27 | Muscle fibrillation (HP:0010546) | 3.02454845 |
28 | Abnormality of homocysteine metabolism (HP:0010919) | 2.97812539 |
29 | Homocystinuria (HP:0002156) | 2.97812539 |
30 | Bilateral microphthalmos (HP:0007633) | 2.97014511 |
31 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.96408134 |
32 | Annular pancreas (HP:0001734) | 2.91660428 |
33 | Maternal diabetes (HP:0009800) | 2.91304648 |
34 | Supernumerary spleens (HP:0009799) | 2.87040601 |
35 | Glioma (HP:0009733) | 2.81359754 |
36 | Vertebral fusion (HP:0002948) | 2.73415336 |
37 | Abnormal lung lobation (HP:0002101) | 2.72387744 |
38 | Ulnar bowing (HP:0003031) | 2.72238141 |
39 | Shawl scrotum (HP:0000049) | 2.67513268 |
40 | Orthostatic hypotension (HP:0001278) | 2.67288082 |
41 | Vertebral hypoplasia (HP:0008417) | 2.62557905 |
42 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 2.62557905 |
43 | Absent thumb (HP:0009777) | 2.59708555 |
44 | Ectopic kidney (HP:0000086) | 2.57595751 |
45 | Abnormal hemoglobin (HP:0011902) | 2.56741192 |
46 | Absent septum pellucidum (HP:0001331) | 2.53450248 |
47 | Patellar aplasia (HP:0006443) | 2.52638747 |
48 | Abdominal situs inversus (HP:0003363) | 2.52452294 |
49 | Abnormality of abdominal situs (HP:0011620) | 2.52452294 |
50 | Medulloblastoma (HP:0002885) | 2.52429473 |
51 | Partial duplication of thumb phalanx (HP:0009944) | 2.47618983 |
52 | Basal cell carcinoma (HP:0002671) | 2.46610105 |
53 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.46364945 |
54 | Trismus (HP:0000211) | 2.46252336 |
55 | Facial cleft (HP:0002006) | 2.46114259 |
56 | Missing ribs (HP:0000921) | 2.45366860 |
57 | Abnormality of the septum pellucidum (HP:0007375) | 2.44612900 |
58 | Intestinal atresia (HP:0011100) | 2.43885062 |
59 | Broad alveolar ridges (HP:0000187) | 2.43062871 |
60 | Abnormal number of incisors (HP:0011064) | 2.41262015 |
61 | Fused cervical vertebrae (HP:0002949) | 2.40026156 |
62 | Abnormal number of erythroid precursors (HP:0012131) | 2.38943934 |
63 | Multiple enchondromatosis (HP:0005701) | 2.38640944 |
64 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.37191658 |
65 | Choanal stenosis (HP:0000452) | 2.36939513 |
66 | Abnormality of the ileum (HP:0001549) | 2.35499851 |
67 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.33053169 |
68 | Breast aplasia (HP:0100783) | 2.32160301 |
69 | Increased IgM level (HP:0003496) | 2.31993931 |
70 | Breast hypoplasia (HP:0003187) | 2.29568962 |
71 | Spinal muscular atrophy (HP:0007269) | 2.28828644 |
72 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.28345474 |
73 | Abnormality of the salivary glands (HP:0010286) | 2.28310219 |
74 | Spastic diplegia (HP:0001264) | 2.26282736 |
75 | Esophageal atresia (HP:0002032) | 2.24447899 |
76 | Gastrointestinal atresia (HP:0002589) | 2.24265252 |
77 | Morphological abnormality of the inner ear (HP:0011390) | 2.22939913 |
78 | Turricephaly (HP:0000262) | 2.21121635 |
79 | Progressive muscle weakness (HP:0003323) | 2.19815995 |
80 | Horseshoe kidney (HP:0000085) | 2.19375308 |
81 | Aplasia/Hypoplasia of the breasts (HP:0010311) | 2.18214433 |
82 | Large earlobe (HP:0009748) | 2.16701816 |
83 | Partial duplication of the phalanx of hand (HP:0009999) | 2.16262689 |
84 | Macrocytic anemia (HP:0001972) | 2.16112112 |
85 | Peripheral hypomyelination (HP:0007182) | 2.15133357 |
86 | Volvulus (HP:0002580) | 2.14606758 |
87 | White forelock (HP:0002211) | 2.14592727 |
88 | Calcaneovalgus deformity (HP:0001848) | 2.13966689 |
89 | Duplication of thumb phalanx (HP:0009942) | 2.13929078 |
90 | Embryonal renal neoplasm (HP:0011794) | 2.13916800 |
91 | Triphalangeal thumb (HP:0001199) | 2.12680762 |
92 | Supernumerary ribs (HP:0005815) | 2.12284125 |
93 | Carpal bone hypoplasia (HP:0001498) | 2.11609497 |
94 | Alopecia of scalp (HP:0002293) | 2.10263596 |
95 | Chromsome breakage (HP:0040012) | 2.09967906 |
96 | Cortical dysplasia (HP:0002539) | 2.08137700 |
97 | Increased nuchal translucency (HP:0010880) | 2.07161844 |
98 | Hemivertebrae (HP:0002937) | 2.06855535 |
99 | Impulsivity (HP:0100710) | 2.06087397 |
100 | Abnormality of the lacrimal duct (HP:0011481) | 2.05301603 |
101 | Supernumerary bones of the axial skeleton (HP:0009144) | 2.04710739 |
102 | Squamous cell carcinoma (HP:0002860) | 2.03718891 |
103 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.03516611 |
104 | Short 5th finger (HP:0009237) | 2.02486838 |
105 | Poikiloderma (HP:0001029) | 1.97754906 |
106 | Pterygium (HP:0001059) | 1.96314987 |
107 | Dysautonomia (HP:0002459) | 1.96086903 |
108 | Poor suck (HP:0002033) | 1.95659834 |
109 | Patchy hypopigmentation of hair (HP:0011365) | 1.95033223 |
110 | Abnormality of the preputium (HP:0100587) | 1.93117044 |
111 | Vertebral clefting (HP:0008428) | 1.92946173 |
112 | Pallor (HP:0000980) | 1.92553046 |
113 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.91539812 |
114 | Abnormal sex determination (HP:0012244) | 1.90114822 |
115 | Sex reversal (HP:0012245) | 1.90114822 |
116 | Acute necrotizing encephalopathy (HP:0006965) | 1.89143062 |
117 | Muscle fiber atrophy (HP:0100295) | 1.89131047 |
118 | Congenital hip dislocation (HP:0001374) | 1.88874571 |
119 | Premature graying of hair (HP:0002216) | 1.87977593 |
120 | Chronic bronchitis (HP:0004469) | 1.87578750 |
121 | Broad distal phalanx of finger (HP:0009836) | 1.87348990 |
122 | Optic nerve hypoplasia (HP:0000609) | 1.86759820 |
123 | Hypotelorism (HP:0000601) | 1.86664967 |
124 | Abnormality of chromosome stability (HP:0003220) | 1.86625537 |
125 | Hypochromic anemia (HP:0001931) | 1.86091069 |
126 | Hamartoma (HP:0010566) | 1.85924672 |
127 | Premature ovarian failure (HP:0008209) | 1.85657862 |
128 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 1.85556056 |
129 | Abnormality of the aortic arch (HP:0012303) | 1.82382411 |
130 | Tracheoesophageal fistula (HP:0002575) | 1.81278593 |
131 | Preaxial foot polydactyly (HP:0001841) | 1.81138229 |
132 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 1.81080087 |
133 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.80839006 |
134 | Coronal craniosynostosis (HP:0004440) | 1.80445996 |
135 | Nasal speech (HP:0001611) | 1.80359499 |
136 | Short chin (HP:0000331) | 1.79857232 |
137 | Pseudobulbar signs (HP:0002200) | 1.79848648 |
138 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 1.79773459 |
139 | Absent eyebrow (HP:0002223) | 1.79650664 |
140 | Meckel diverticulum (HP:0002245) | 1.79564194 |
141 | Sensory axonal neuropathy (HP:0003390) | 1.79449644 |
142 | Alacrima (HP:0000522) | 1.79215678 |
143 | Anophthalmia (HP:0000528) | 1.78934797 |
144 | Deformed tarsal bones (HP:0008119) | 1.76940913 |
145 | Cleft eyelid (HP:0000625) | 1.75792821 |
146 | Preauricular skin tag (HP:0000384) | 1.75734118 |
147 | Atresia of the external auditory canal (HP:0000413) | 1.75590689 |
148 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.75367361 |
149 | Small intestinal stenosis (HP:0012848) | 1.74959204 |
150 | Duodenal stenosis (HP:0100867) | 1.74959204 |
151 | Hepatoblastoma (HP:0002884) | 1.74849081 |
152 | Dysphonia (HP:0001618) | 1.74114095 |
153 | Hypotrichosis (HP:0001006) | 1.72861191 |
154 | Acute encephalopathy (HP:0006846) | 1.72556865 |
155 | Broad thumb (HP:0011304) | 1.72516897 |
156 | Hyperglycinemia (HP:0002154) | 1.71606272 |
157 | Absent epiphyses (HP:0010577) | 1.70654070 |
158 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.70654070 |
159 | Cellular immunodeficiency (HP:0005374) | 1.69941525 |
160 | Colon cancer (HP:0003003) | 1.69478153 |
161 | Testicular atrophy (HP:0000029) | 1.69376128 |
162 | Cerebral aneurysm (HP:0004944) | 1.68954922 |
163 | Abnormality of the nasolacrimal system (HP:0000614) | 1.68547602 |
164 | Generalized hypotonia (HP:0001290) | 1.68169317 |
165 | Abnormality of cochlea (HP:0000375) | 1.66947680 |
166 | Abnormality of the duodenum (HP:0002246) | 1.66497482 |
167 | Thin ribs (HP:0000883) | 1.64314870 |
168 | Rocker bottom foot (HP:0001838) | 1.64193094 |
169 | High anterior hairline (HP:0009890) | 1.63947069 |
170 | Cerebral hypomyelination (HP:0006808) | 1.63616860 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDK12 | 5.05178737 |
2 | ICK | 4.47985387 |
3 | DDR2 | 3.51135420 |
4 | VRK2 | 3.46255273 |
5 | TYRO3 | 3.19700094 |
6 | MAPK15 | 3.02058498 |
7 | MATK | 2.78491641 |
8 | MKNK1 | 2.63422911 |
9 | EPHA2 | 2.60235006 |
10 | CDK7 | 2.56376549 |
11 | MAP3K6 | 2.47426109 |
12 | ZAK | 2.38649334 |
13 | PBK | 2.31132029 |
14 | NME2 | 2.29752281 |
15 | CDK19 | 2.28371975 |
16 | AKT3 | 2.27286541 |
17 | SMG1 | 2.27251481 |
18 | TAF1 | 2.14114585 |
19 | TSSK6 | 2.09303108 |
20 | PLK3 | 2.04695421 |
21 | TNIK | 2.01700259 |
22 | MAP3K11 | 1.97642076 |
23 | LATS2 | 1.92843192 |
24 | TTK | 1.91516306 |
25 | NME1 | 1.88309988 |
26 | GRK6 | 1.77766408 |
27 | BMX | 1.73096541 |
28 | FGR | 1.70803797 |
29 | WEE1 | 1.70274409 |
30 | CDC7 | 1.70188935 |
31 | BUB1 | 1.67728450 |
32 | PINK1 | 1.65230789 |
33 | VRK1 | 1.65014304 |
34 | UHMK1 | 1.64338354 |
35 | CHEK2 | 1.61221773 |
36 | PLK1 | 1.60633602 |
37 | PDGFRA | 1.57676456 |
38 | MAP3K10 | 1.54152846 |
39 | GRK5 | 1.51470456 |
40 | DYRK1B | 1.51181365 |
41 | CSK | 1.48809203 |
42 | STK16 | 1.46683133 |
43 | DAPK1 | 1.46526427 |
44 | DYRK3 | 1.46222014 |
45 | YES1 | 1.42025424 |
46 | RPS6KB2 | 1.41250896 |
47 | PLK4 | 1.41140935 |
48 | EEF2K | 1.40052911 |
49 | PRKD2 | 1.36628289 |
50 | NEK1 | 1.27282020 |
51 | PIM1 | 1.17203813 |
52 | ERBB4 | 1.16765816 |
53 | PASK | 1.15940133 |
54 | NEK2 | 1.15906384 |
55 | STK10 | 1.13513969 |
56 | CDK6 | 1.12645867 |
57 | PAK4 | 1.12300366 |
58 | KDR | 1.12159270 |
59 | MTOR | 1.09597221 |
60 | BRSK2 | 1.04603488 |
61 | ALK | 1.03448027 |
62 | CHEK1 | 1.00198552 |
63 | DMPK | 0.92413373 |
64 | MAP3K9 | 0.92218224 |
65 | PIM2 | 0.91022820 |
66 | BRSK1 | 0.89183713 |
67 | CDK2 | 0.89008050 |
68 | HIPK2 | 0.88385730 |
69 | AURKA | 0.87210730 |
70 | GSK3A | 0.86891602 |
71 | TRIM28 | 0.86875689 |
72 | ATR | 0.86687744 |
73 | NUAK1 | 0.86606387 |
74 | CDC42BPA | 0.85927174 |
75 | ERN1 | 0.84372938 |
76 | CAMK1D | 0.81567068 |
77 | STK3 | 0.78204087 |
78 | MST4 | 0.75946842 |
79 | AURKB | 0.75940942 |
80 | CAMK1G | 0.75639739 |
81 | TRIB3 | 0.75503171 |
82 | CDK4 | 0.73024948 |
83 | BRAF | 0.72412377 |
84 | RPS6KL1 | 0.70315596 |
85 | RPS6KC1 | 0.70315596 |
86 | MAPKAPK3 | 0.69964968 |
87 | ATM | 0.68262217 |
88 | FGFR1 | 0.68076445 |
89 | BRD4 | 0.66948324 |
90 | FGFR2 | 0.66193938 |
91 | CSNK1G1 | 0.65986308 |
92 | CDK3 | 0.65669890 |
93 | PRKCI | 0.65659335 |
94 | AKT2 | 0.63109144 |
95 | DYRK2 | 0.61464144 |
96 | GRK1 | 0.60288707 |
97 | RPS6KA5 | 0.59939610 |
98 | TLK1 | 0.59495842 |
99 | BCKDK | 0.59470075 |
100 | TESK2 | 0.59353073 |
101 | PRKDC | 0.58506865 |
102 | LATS1 | 0.56261865 |
103 | ADRBK2 | 0.54822632 |
104 | PNCK | 0.54793943 |
105 | PTK2 | 0.54366150 |
106 | MAP3K8 | 0.53827613 |
107 | MAPK7 | 0.52857878 |
108 | RPS6KA6 | 0.52616177 |
109 | PHKG1 | 0.52391239 |
110 | PHKG2 | 0.52391239 |
111 | WNK3 | 0.52350070 |
112 | RPS6KA1 | 0.52263458 |
113 | SRPK1 | 0.51965608 |
114 | CDK1 | 0.51881784 |
115 | MAPK11 | 0.51624466 |
116 | CSNK1E | 0.51512894 |
117 | STK38L | 0.49615432 |
118 | CSNK2A2 | 0.47945796 |
119 | MARK2 | 0.47071878 |
120 | CSF1R | 0.46966415 |
121 | CSNK2A1 | 0.45759586 |
122 | MAPK1 | 0.44977658 |
123 | PAK1 | 0.44688751 |
124 | CAMK4 | 0.43856118 |
125 | ILK | 0.43544807 |
126 | MAPK14 | 0.42833517 |
127 | NLK | 0.42776306 |
128 | MAPK10 | 0.41867291 |
129 | TAOK2 | 0.39830586 |
130 | PRKG2 | 0.39235935 |
131 | MET | 0.38827337 |
132 | FLT3 | 0.38179286 |
133 | PRPF4B | 0.36088544 |
134 | PRKAA1 | 0.35417151 |
135 | CSNK1G3 | 0.35203110 |
136 | GSK3B | 0.34914534 |
137 | CDK11A | 0.33746032 |
138 | DAPK3 | 0.33205380 |
139 | MOS | 0.33086312 |
140 | EIF2AK2 | 0.32095226 |
141 | STK38 | 0.30913126 |
142 | DYRK1A | 0.30895666 |
143 | CDK15 | 0.30513928 |
144 | MARK3 | 0.30451187 |
145 | NTRK1 | 0.29722019 |
146 | STK4 | 0.29424043 |
147 | CDK18 | 0.28953974 |
148 | RIPK1 | 0.28547073 |
149 | MKNK2 | 0.28537942 |
150 | CSNK1G2 | 0.25905438 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Mismatch repair_Homo sapiens_hsa03430 | 4.78846511 |
2 | DNA replication_Homo sapiens_hsa03030 | 4.09586746 |
3 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 4.00518371 |
4 | Base excision repair_Homo sapiens_hsa03410 | 3.65489552 |
5 | RNA transport_Homo sapiens_hsa03013 | 3.03801874 |
6 | Spliceosome_Homo sapiens_hsa03040 | 2.98337563 |
7 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.50370115 |
8 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.36974211 |
9 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 2.34769199 |
10 | Homologous recombination_Homo sapiens_hsa03440 | 2.26939428 |
11 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.22605500 |
12 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.20852306 |
13 | Cell cycle_Homo sapiens_hsa04110 | 2.06251244 |
14 | Ribosome_Homo sapiens_hsa03010 | 2.04086356 |
15 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.85316288 |
16 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.84449790 |
17 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.75318894 |
18 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.72392449 |
19 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.68572150 |
20 | Parkinsons disease_Homo sapiens_hsa05012 | 1.66174136 |
21 | RNA polymerase_Homo sapiens_hsa03020 | 1.65431744 |
22 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.64247766 |
23 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.62477625 |
24 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.62181351 |
25 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.60473917 |
26 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.54113389 |
27 | Huntingtons disease_Homo sapiens_hsa05016 | 1.49049831 |
28 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.48357351 |
29 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.44801153 |
30 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.41451891 |
31 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.40495240 |
32 | Adherens junction_Homo sapiens_hsa04520 | 1.38598523 |
33 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.30931622 |
34 | Thyroid cancer_Homo sapiens_hsa05216 | 1.29201032 |
35 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.29087930 |
36 | RNA degradation_Homo sapiens_hsa03018 | 1.26463794 |
37 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.26082231 |
38 | Bladder cancer_Homo sapiens_hsa05219 | 1.25777527 |
39 | Purine metabolism_Homo sapiens_hsa00230 | 1.24840925 |
40 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.22472703 |
41 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.21544162 |
42 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.21209614 |
43 | Sulfur relay system_Homo sapiens_hsa04122 | 1.17768502 |
44 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.16672157 |
45 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.16444199 |
46 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.13527010 |
47 | Wnt signaling pathway_Homo sapiens_hsa04310 | 1.04087223 |
48 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.00076605 |
49 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.98590405 |
50 | Basal transcription factors_Homo sapiens_hsa03022 | 0.98360265 |
51 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.97854933 |
52 | Galactose metabolism_Homo sapiens_hsa00052 | 0.96901223 |
53 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.94670765 |
54 | Alzheimers disease_Homo sapiens_hsa05010 | 0.93275057 |
55 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.89536594 |
56 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.89391174 |
57 | Tight junction_Homo sapiens_hsa04530 | 0.88780006 |
58 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.87830050 |
59 | Lysine degradation_Homo sapiens_hsa00310 | 0.86197456 |
60 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.84695874 |
61 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.79976193 |
62 | Colorectal cancer_Homo sapiens_hsa05210 | 0.78719538 |
63 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.77343855 |
64 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.73903327 |
65 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.73172698 |
66 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.72223265 |
67 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.69970631 |
68 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.69557111 |
69 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.68873897 |
70 | Proteasome_Homo sapiens_hsa03050 | 0.66588233 |
71 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.66577369 |
72 | Protein export_Homo sapiens_hsa03060 | 0.66428632 |
73 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.63553419 |
74 | Pathways in cancer_Homo sapiens_hsa05200 | 0.61995210 |
75 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.61910534 |
76 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.60927524 |
77 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.60466713 |
78 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.55152544 |
79 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.54960479 |
80 | Metabolic pathways_Homo sapiens_hsa01100 | 0.54104349 |
81 | Alcoholism_Homo sapiens_hsa05034 | 0.50568673 |
82 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.50385530 |
83 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.49730963 |
84 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.48332058 |
85 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.47820772 |
86 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.46414118 |
87 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.46108879 |
88 | HTLV-I infection_Homo sapiens_hsa05166 | 0.45990998 |
89 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.42266076 |
90 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.42206682 |
91 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.41799819 |
92 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.41019818 |
93 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.40423109 |
94 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.40222024 |
95 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.39584090 |
96 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.37848262 |
97 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.37816102 |
98 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.37689389 |
99 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.37128064 |
100 | Circadian rhythm_Homo sapiens_hsa04710 | 0.37095270 |
101 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.35392256 |
102 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.34445254 |
103 | Endometrial cancer_Homo sapiens_hsa05213 | 0.34328689 |
104 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.34261596 |
105 | Viral myocarditis_Homo sapiens_hsa05416 | 0.33638075 |
106 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.32320837 |
107 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.31640178 |
108 | Melanoma_Homo sapiens_hsa05218 | 0.31098024 |
109 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.30706277 |
110 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.30503708 |
111 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.30204900 |
112 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.28498417 |
113 | Shigellosis_Homo sapiens_hsa05131 | 0.28457089 |
114 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.28170696 |
115 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.27961983 |
116 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.26712600 |
117 | Focal adhesion_Homo sapiens_hsa04510 | 0.26612046 |
118 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.25196982 |
119 | Carbon metabolism_Homo sapiens_hsa01200 | 0.24255928 |
120 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.22800394 |
121 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.22405444 |
122 | Prostate cancer_Homo sapiens_hsa05215 | 0.22337057 |
123 | Gap junction_Homo sapiens_hsa04540 | 0.21959577 |
124 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.21554801 |
125 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.19576048 |
126 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.17119684 |
127 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.16299761 |
128 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.16297397 |
129 | Melanogenesis_Homo sapiens_hsa04916 | 0.15568031 |
130 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.14709252 |
131 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.13144991 |
132 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.12519557 |
133 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.12382128 |