FOXJ3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1monoubiquitinated protein deubiquitination (GO:0035520)4.56767958
2mitotic sister chromatid cohesion (GO:0007064)4.52946324
3piRNA metabolic process (GO:0034587)4.25842232
4histone H2A monoubiquitination (GO:0035518)3.91741147
5regulation of meiosis I (GO:0060631)3.91403316
6negative regulation of retinoic acid receptor signaling pathway (GO:0048387)3.81014663
7regulation of histone H3-K27 methylation (GO:0061085)3.77108496
8mitotic chromosome condensation (GO:0007076)3.75473353
9phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.67391183
10regulation of RNA export from nucleus (GO:0046831)3.64810438
11negative regulation of hormone biosynthetic process (GO:0032353)3.54506269
12negative regulation of hormone metabolic process (GO:0032351)3.54506269
13female gamete generation (GO:0007292)3.50407160
14cytoplasmic mRNA processing body assembly (GO:0033962)3.48508246
15regulation of sister chromatid cohesion (GO:0007063)3.45319498
16regulation of meiosis (GO:0040020)3.42214226
17regulation of NFAT protein import into nucleus (GO:0051532)3.41307453
18sister chromatid cohesion (GO:0007062)3.40959662
19histone H3-K36 demethylation (GO:0070544)3.40036443
20snRNA transcription (GO:0009301)3.33766610
21negative regulation of meiosis (GO:0045835)3.30954100
22embryonic retina morphogenesis in camera-type eye (GO:0060059)3.30777164
23nuclear pore complex assembly (GO:0051292)3.30598097
24mitotic metaphase plate congression (GO:0007080)3.24286563
25positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.24014772
26positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.24014772
27positive regulation of mitotic sister chromatid separation (GO:1901970)3.24014772
28dosage compensation (GO:0007549)3.22128739
29regulation of clathrin-mediated endocytosis (GO:2000369)3.13595361
30coronary vasculature morphogenesis (GO:0060977)3.12228023
31DNA damage response, signal transduction resulting in transcription (GO:0042772)3.09233168
32DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla3.08907311
33histone lysine demethylation (GO:0070076)3.06533791
34regulation of establishment of cell polarity (GO:2000114)3.06321199
35pre-miRNA processing (GO:0031054)3.05620078
36regulation of nucleobase-containing compound transport (GO:0032239)3.04961838
37interkinetic nuclear migration (GO:0022027)3.03799584
38DNA methylation involved in gamete generation (GO:0043046)3.00606939
39histone H3-K4 trimethylation (GO:0080182)2.98537500
40male meiosis (GO:0007140)2.98422782
41histone deubiquitination (GO:0016578)2.96335270
42histone H3-K4 methylation (GO:0051568)2.96051729
43histone H2A ubiquitination (GO:0033522)2.95054510
44histone demethylation (GO:0016577)2.94173626
45histone H4-K16 acetylation (GO:0043984)2.92601251
46oocyte maturation (GO:0001556)2.91470720
47peptidyl-lysine methylation (GO:0018022)2.90437100
48peptidyl-lysine trimethylation (GO:0018023)2.87234595
49phosphatidylinositol phosphorylation (GO:0046854)2.86986631
50meiotic chromosome segregation (GO:0045132)2.86688829
51regulation of histone methylation (GO:0031060)2.85220342
52gamma-aminobutyric acid transport (GO:0015812)2.84368397
53establishment of protein localization to Golgi (GO:0072600)2.84306134
54negative regulation of circadian rhythm (GO:0042754)2.83958711
55nuclear pore organization (GO:0006999)2.82364235
56protein targeting to Golgi (GO:0000042)2.81129377
57negative regulation of histone modification (GO:0031057)2.80932249
58DNA methylation (GO:0006306)2.80014196
59DNA alkylation (GO:0006305)2.80014196
60nucleus organization (GO:0006997)2.79341341
61metaphase plate congression (GO:0051310)2.79281092
62COPII vesicle coating (GO:0048208)2.77775177
63retrograde transport, vesicle recycling within Golgi (GO:0000301)2.77021510
64gene silencing by RNA (GO:0031047)2.76947615
65Golgi to endosome transport (GO:0006895)2.76777467
66regulation of meiotic cell cycle (GO:0051445)2.76075479
67positive regulation of granulocyte differentiation (GO:0030854)2.73487249
68establishment of chromosome localization (GO:0051303)2.72721981
69vesicle transport along microtubule (GO:0047496)2.72665889
70regulation of transforming growth factor beta2 production (GO:0032909)2.72542358
71microtubule nucleation (GO:0007020)2.71856155
72mitotic sister chromatid segregation (GO:0000070)2.71569996
73regulation of retinoic acid receptor signaling pathway (GO:0048385)2.70463824
74protein dealkylation (GO:0008214)2.69927061
75protein demethylation (GO:0006482)2.69927061
76regulation of ARF protein signal transduction (GO:0032012)2.69812462
77peptidyl-threonine modification (GO:0018210)2.69699285
78regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.69661469
79positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.69661469
80corticosteroid receptor signaling pathway (GO:0031958)2.69209635
81peptidyl-threonine dephosphorylation (GO:0035970)2.68570129
82regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.68226173
83negative regulation of histone methylation (GO:0031061)2.67121406
84macroautophagy (GO:0016236)2.66670678
85negative regulation of chromatin modification (GO:1903309)2.65395003
86synaptonemal complex assembly (GO:0007130)2.64860993
87protein K48-linked deubiquitination (GO:0071108)2.63112158
88microtubule severing (GO:0051013)2.61594510
89regulation of histone H3-K4 methylation (GO:0051569)2.60362316
90cerebellar Purkinje cell differentiation (GO:0021702)2.59665262
91peptidyl-lysine dimethylation (GO:0018027)2.59385300
92positive regulation of gene expression, epigenetic (GO:0045815)2.58138389
93inner cell mass cell proliferation (GO:0001833)2.58019246
94DNA damage induced protein phosphorylation (GO:0006975)2.57569272
95pericardium development (GO:0060039)2.56893028
96protein localization to microtubule (GO:0035372)2.56582787
97positive regulation of CREB transcription factor activity (GO:0032793)2.56409071
98female gonad development (GO:0008585)2.56383093
99histone lysine methylation (GO:0034968)2.55340561
100histone methylation (GO:0016571)2.55270182
101regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.54588675
102regulation of exit from mitosis (GO:0007096)2.53956115
103sister chromatid segregation (GO:0000819)2.50964590
104nucleus localization (GO:0051647)2.50576419
105oogenesis (GO:0048477)2.50385023
106protein monoubiquitination (GO:0006513)2.49847638
107positive regulation of meiosis (GO:0045836)2.49467562
108regulation of establishment or maintenance of cell polarity (GO:0032878)2.49150995
109regulation of female gonad development (GO:2000194)2.49134868
110lipid phosphorylation (GO:0046834)2.48428922
111myotube differentiation (GO:0014902)2.47327937
112regulation of centriole replication (GO:0046599)2.46818833
113positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.46786901
114negative regulation of cAMP-mediated signaling (GO:0043951)2.46680781
115meiotic cell cycle (GO:0051321)2.45985730
116response to stimulus involved in regulation of muscle adaptation (GO:0014874)2.45372039
117mRNA splice site selection (GO:0006376)2.45323217
118embryonic camera-type eye morphogenesis (GO:0048596)2.43697601
119type B pancreatic cell development (GO:0003323)2.42841001
120positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.41090572
121regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.41090572
122histone H3-K9 demethylation (GO:0033169)2.40688196
123histone H3-K9 modification (GO:0061647)2.40166558
124negative regulation of potassium ion transmembrane transport (GO:1901380)2.37247722
125glucocorticoid receptor signaling pathway (GO:0042921)2.37219447
126histone H4-K12 acetylation (GO:0043983)2.37130438
127protein K11-linked deubiquitination (GO:0035871)2.34686730
128chromosome segregation (GO:0007059)2.34134059
129pore complex assembly (GO:0046931)2.34035010
130regulation of histone H3-K9 methylation (GO:0051570)2.33047084
131histone acetylation (GO:0016573)2.32655806
132response to inactivity (GO:0014854)2.32241748
133positive regulation of chromosome segregation (GO:0051984)2.32125596
134histone monoubiquitination (GO:0010390)2.32010504
135synaptonemal complex organization (GO:0070193)2.31330048
136negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.31300593
137kinetochore assembly (GO:0051382)2.31182398
138histone H4 acetylation (GO:0043967)2.31118314
139positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.30927463
140histone H3-K9 methylation (GO:0051567)2.30584792
141N-terminal protein amino acid acetylation (GO:0006474)2.30383659
142peptidyl-threonine phosphorylation (GO:0018107)2.30005073
143internal peptidyl-lysine acetylation (GO:0018393)2.29892857
144nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.29727251
145negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.29673656
146negative regulation of translation, ncRNA-mediated (GO:0040033)2.29673656
147regulation of translation, ncRNA-mediated (GO:0045974)2.29673656
148positive regulation of meiotic cell cycle (GO:0051446)2.29255058
149stress granule assembly (GO:0034063)2.29237315
150protein K6-linked ubiquitination (GO:0085020)2.29028596
151protein localization to chromosome (GO:0034502)2.28783958
152NLS-bearing protein import into nucleus (GO:0006607)2.28592795
153attachment of spindle microtubules to kinetochore (GO:0008608)2.27938827
154regulation of spindle organization (GO:0090224)2.27883989
155definitive hemopoiesis (GO:0060216)2.26923055
156kinetochore organization (GO:0051383)2.26603755
157positive regulation by host of viral transcription (GO:0043923)2.25735981
158protein deubiquitination (GO:0016579)2.25723886
159protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787)2.25091788
160maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.23510266
161notochord development (GO:0030903)2.22770540
162positive regulation of mRNA catabolic process (GO:0061014)2.22676293
163cardiac muscle adaptation (GO:0014887)2.22186791
164cardiac muscle hypertrophy in response to stress (GO:0014898)2.22186791
165muscle hypertrophy in response to stress (GO:0003299)2.22186791
166negative regulation of neurotransmitter secretion (GO:0046929)2.22098416
167negative regulation of DNA repair (GO:0045738)2.20593493
168carnitine shuttle (GO:0006853)2.20229607

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SALL1_21062744_ChIP-ChIP_HESCs_Human3.44052117
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.40105648
3SMAD_19615063_ChIP-ChIP_OVARY_Human3.23360136
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.18606250
5EZH2_22144423_ChIP-Seq_EOC_Human3.11173578
6FOXM1_23109430_ChIP-Seq_U2OS_Human3.08425959
7TP63_19390658_ChIP-ChIP_HaCaT_Human2.49330819
8SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.40598342
9IGF1R_20145208_ChIP-Seq_DFB_Human2.23371692
10RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.12528889
11KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.09035735
12CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.07448514
13ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.05871085
14VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.01260797
15GBX2_23144817_ChIP-Seq_PC3_Human2.00274684
16E2F7_22180533_ChIP-Seq_HELA_Human1.96449900
17TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.93868283
18POU3F2_20337985_ChIP-ChIP_501MEL_Human1.87031008
19* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.77939569
20FLI1_27457419_Chip-Seq_LIVER_Mouse1.77867949
21AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.77587158
22GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.69826524
23CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.69641936
24STAT3_23295773_ChIP-Seq_U87_Human1.68702298
25SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.65635443
26FUS_26573619_Chip-Seq_HEK293_Human1.62517895
27MYC_22102868_ChIP-Seq_BL_Human1.62241164
28* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.62164710
29SMAD4_21799915_ChIP-Seq_A2780_Human1.60459880
30* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.58892490
31WT1_19549856_ChIP-ChIP_CCG9911_Human1.58137625
32TCF7_22412390_ChIP-Seq_EML_Mouse1.57356632
33RNF2_27304074_Chip-Seq_NSC_Mouse1.53539329
34* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.49352032
35TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.49079907
36HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.46672261
37PCGF2_27294783_Chip-Seq_ESCs_Mouse1.46555660
38TP53_16413492_ChIP-PET_HCT116_Human1.44597670
39NANOG_18555785_Chip-Seq_ESCs_Mouse1.43063815
40STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.42454756
41WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.42330175
42MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.42265472
43CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.41401335
44TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.40946410
45PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.40628282
46* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.39424135
47RUNX_20019798_ChIP-Seq_JUKART_Human1.39206978
48EWS_26573619_Chip-Seq_HEK293_Human1.38850885
49AHR_22903824_ChIP-Seq_MCF-7_Human1.38677796
50POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.38201553
51TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.38201553
52FOXO3_23340844_ChIP-Seq_DLD1_Human1.37400409
53* KDM2B_26808549_Chip-Seq_JURKAT_Human1.36974392
54CHD1_26751641_Chip-Seq_LNCaP_Human1.36761140
55PKCTHETA_26484144_Chip-Seq_BREAST_Human1.35943259
56* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.34099865
57CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.34065356
58RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.33807934
59NFIB_24661679_ChIP-Seq_LUNG_Mouse1.33568971
60YAP1_20516196_ChIP-Seq_MESCs_Mouse1.32381155
61MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.32069926
62TCF4_23295773_ChIP-Seq_U87_Human1.31679387
63ZFP57_27257070_Chip-Seq_ESCs_Mouse1.29121542
64* ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.28378084
65LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.28316549
66KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.26582079
67KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.26582079
68KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.26582079
69ESR1_20079471_ChIP-ChIP_T-47D_Human1.24746708
70CIITA_25753668_ChIP-Seq_RAJI_Human1.23653716
71CTBP2_25329375_ChIP-Seq_LNCAP_Human1.23620922
72ZFP281_27345836_Chip-Seq_ESCs_Mouse1.23164481
73GATA1_26923725_Chip-Seq_HPCs_Mouse1.23086088
74AR_21572438_ChIP-Seq_LNCaP_Human1.22864328
75* TCF4_18268006_ChIP-ChIP_LS174T_Human1.22505783
76SUZ12_27294783_Chip-Seq_NPCs_Mouse1.22112297
77NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.21436696
78ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.21435870
79* FOXA2_19822575_ChIP-Seq_HepG2_Human1.20696684
80RBPJ_22232070_ChIP-Seq_NCS_Mouse1.20674232
81* FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.20426846
82KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.18630541
83* KDM2B_26808549_Chip-Seq_DND41_Human1.17709549
84ARNT_22903824_ChIP-Seq_MCF-7_Human1.16986595
85AR_25329375_ChIP-Seq_VCAP_Human1.15351688
86STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.14625370
87RUNX1_26923725_Chip-Seq_HPCs_Mouse1.14380366
88CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.14210075
89EGR1_19374776_ChIP-ChIP_THP-1_Human1.14132344
90* AR_19668381_ChIP-Seq_PC3_Human1.13550116
91NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.13482874
92P53_22127205_ChIP-Seq_FIBROBLAST_Human1.13390720
93PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.13365987
94WT1_25993318_ChIP-Seq_PODOCYTE_Human1.13060759
95P300_19829295_ChIP-Seq_ESCs_Human1.12998889
96E2F1_18555785_Chip-Seq_ESCs_Mouse1.11834495
97PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.11637168
98PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.08839726
99EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.06718436
100FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.05508657
101* SOX2_21211035_ChIP-Seq_LN229_Gbm1.05256031
102EP300_21415370_ChIP-Seq_HL-1_Mouse1.04905884
103PIAS1_25552417_ChIP-Seq_VCAP_Human1.04814945
104* TBL1_22424771_ChIP-Seq_293T_Human1.04665529
105E2F1_21310950_ChIP-Seq_MCF-7_Human1.04196176
106RXR_22108803_ChIP-Seq_LS180_Human1.03466586
107SOX9_24532713_ChIP-Seq_HFSC_Mouse1.03343844
108NR3C1_23031785_ChIP-Seq_PC12_Mouse1.03282418
109GF1B_26923725_Chip-Seq_HPCs_Mouse1.03009784
110NFE2_27457419_Chip-Seq_LIVER_Mouse1.02791300
111EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.01740825
112MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01384656
113ISL1_27105846_Chip-Seq_CPCs_Mouse1.00646310
114STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.00493027
115RNF2_27304074_Chip-Seq_ESCs_Mouse0.99086900
116GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.98996055
117NR3C1_21868756_ChIP-Seq_MCF10A_Human0.98852557
118EZH2_27294783_Chip-Seq_NPCs_Mouse0.98818559
119KDM2B_26808549_Chip-Seq_SUP-B15_Human0.98166030
120* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.98021257
121DROSHA_22980978_ChIP-Seq_HELA_Human0.97748482
122* P300_27058665_Chip-Seq_ZR-75-30cells_Human0.97411432
123RARB_27405468_Chip-Seq_BRAIN_Mouse0.97163147
124E2F4_17652178_ChIP-ChIP_JURKAT_Human0.96682410
125YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.96455940
126TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94574712
127FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.94361565
128LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94359492
129* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.94080466
130CMYC_18555785_Chip-Seq_ESCs_Mouse0.92910568
131PRDM14_20953172_ChIP-Seq_ESCs_Human0.92874342
132* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.92531517
133GATA1_19941827_ChIP-Seq_MEL86_Mouse0.92397996
134GF1_26923725_Chip-Seq_HPCs_Mouse0.92300062
135MYB_26560356_Chip-Seq_TH2_Human0.91991123
136EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.91952377
137CTNNB1_20460455_ChIP-Seq_HCT116_Human0.91273787
138SOX2_18555785_Chip-Seq_ESCs_Mouse0.90843449
139KAP1_22055183_ChIP-Seq_ESCs_Mouse0.90733878
140REST_21632747_ChIP-Seq_MESCs_Mouse0.90443165
141* KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.89592832
142RUNX2_22187159_ChIP-Seq_PCA_Human0.89519730
143CDX2_19796622_ChIP-Seq_MESCs_Mouse0.89433176
144P53_22387025_ChIP-Seq_ESCs_Mouse0.89158417
145SUZ12_18555785_Chip-Seq_ESCs_Mouse0.89156031
146* FOXM1_26456572_ChIP-Seq_MCF-7_Human0.88270413
147TAF15_26573619_Chip-Seq_HEK293_Human0.87915579
148SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.87791778
149NMYC_18555785_Chip-Seq_ESCs_Mouse0.87221828

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002009_preneoplasia4.66285778
2MP0003787_abnormal_imprinting4.66085391
3MP0008877_abnormal_DNA_methylation4.07098065
4MP0000569_abnormal_digit_pigmentation3.27351523
5MP0003121_genomic_imprinting3.08739488
6MP0004859_abnormal_synaptic_plasticity2.54696934
7MP0002822_catalepsy2.53571119
8MP0003646_muscle_fatigue2.23955528
9MP0006292_abnormal_olfactory_placode2.16273278
10MP0005646_abnormal_pituitary_gland2.08531597
11MP0003123_paternal_imprinting2.05499893
12MP0002102_abnormal_ear_morphology1.98168704
13MP0002166_altered_tumor_susceptibility1.86364264
14MP0003221_abnormal_cardiomyocyte_apopto1.85878799
15MP0004233_abnormal_muscle_weight1.83758907
16MP0000751_myopathy1.82255665
17MP0003693_abnormal_embryo_hatching1.79918592
18MP0002877_abnormal_melanocyte_morpholog1.76639791
19MP0005666_abnormal_adipose_tissue1.76019787
20MP0003077_abnormal_cell_cycle1.75625057
21MP0003111_abnormal_nucleus_morphology1.71434283
22MP0005076_abnormal_cell_differentiation1.68840402
23MP0010352_gastrointestinal_tract_polyps1.68529848
24MP0005310_abnormal_salivary_gland1.65357797
25MP0005409_darkened_coat_color1.64747270
26MP0004084_abnormal_cardiac_muscle1.64011424
27MP0010094_abnormal_chromosome_stability1.63939148
28MP0004130_abnormal_muscle_cell1.61414045
29MP0004270_analgesia1.61158351
30MP0003718_maternal_effect1.58749722
31MP0004510_myositis1.55739920
32MP0008007_abnormal_cellular_replicative1.55637272
33MP0004036_abnormal_muscle_relaxation1.54369254
34MP0003937_abnormal_limbs/digits/tail_de1.48897861
35MP0000566_synostosis1.48364925
36MP0003890_abnormal_embryonic-extraembry1.47925150
37MP0008057_abnormal_DNA_replication1.47702012
38MP0005257_abnormal_intraocular_pressure1.44743258
39MP0001849_ear_inflammation1.43096606
40MP0001119_abnormal_female_reproductive1.41180563
41MP0002210_abnormal_sex_determination1.38791739
42MP0003122_maternal_imprinting1.38575890
43MP0004197_abnormal_fetal_growth/weight/1.37779836
44MP0005375_adipose_tissue_phenotype1.37381623
45MP0003699_abnormal_female_reproductive1.36444614
46MP0002084_abnormal_developmental_patter1.36000739
47MP0004264_abnormal_extraembryonic_tissu1.34826117
48MP0010307_abnormal_tumor_latency1.34063439
49* MP0002106_abnormal_muscle_physiology1.33990299
50MP0003755_abnormal_palate_morphology1.33030933
51MP0003763_abnormal_thymus_physiology1.32904104
52MP0001348_abnormal_lacrimal_gland1.31846076
53MP0001346_abnormal_lacrimal_gland1.31683004
54MP0004484_altered_response_of1.30804504
55MP0004087_abnormal_muscle_fiber1.30416866
56MP0000013_abnormal_adipose_tissue1.30074839
57MP0003567_abnormal_fetal_cardiomyocyte1.30026948
58MP0009115_abnormal_fat_cell1.29838787
59MP0005670_abnormal_white_adipose1.29631623
60MP0004043_abnormal_pH_regulation1.28585327
61MP0003635_abnormal_synaptic_transmissio1.28365162
62MP0010630_abnormal_cardiac_muscle1.27940015
63MP0002653_abnormal_ependyma_morphology1.27850496
64MP0002163_abnormal_gland_morphology1.27310247
65MP0000350_abnormal_cell_proliferation1.25303932
66MP0006138_congestive_heart_failure1.21333710
67MP0001929_abnormal_gametogenesis1.20900780
68MP0002085_abnormal_embryonic_tissue1.20453004
69MP0000653_abnormal_sex_gland1.19669102
70MP0010234_abnormal_vibrissa_follicle1.18953596
71MP0001672_abnormal_embryogenesis/_devel1.16994806
72MP0005380_embryogenesis_phenotype1.16994806
73* MP0000759_abnormal_skeletal_muscle1.16322098
74* MP0005369_muscle_phenotype1.16133040
75MP0003935_abnormal_craniofacial_develop1.14261621
76MP0001730_embryonic_growth_arrest1.13986221
77MP0002063_abnormal_learning/memory/cond1.13462681
78MP0001299_abnormal_eye_distance/1.12168437
79MP0002269_muscular_atrophy1.11694097
80MP0005187_abnormal_penis_morphology1.10170829
81MP0004185_abnormal_adipocyte_glucose1.09449375
82MP0002006_tumorigenesis1.05146755
83MP0002108_abnormal_muscle_morphology1.04944865
84MP0000703_abnormal_thymus_morphology1.04640166
85MP0002971_abnormal_brown_adipose1.04625339
86MP0008961_abnormal_basal_metabolism1.04282103
87MP0003984_embryonic_growth_retardation1.04216813
88MP0005451_abnormal_body_composition1.03718383
89MP0003115_abnormal_respiratory_system1.03212850
90MP0001873_stomach_inflammation1.02414252
91MP0004808_abnormal_hematopoietic_stem1.01639589
92MP0003861_abnormal_nervous_system1.00873736
93MP0004811_abnormal_neuron_physiology0.99890238
94MP0002088_abnormal_embryonic_growth/wei0.99242384
95MP0002734_abnormal_mechanical_nocicepti0.99084723
96MP0000778_abnormal_nervous_system0.97546111
97MP0009046_muscle_twitch0.94615347
98MP0001943_abnormal_respiration0.94449872
99MP0005386_behavior/neurological_phenoty0.93739221
100MP0000432_abnormal_head_morphology0.93356377
101MP0000003_abnormal_adipose_tissue0.93173933
102MP0005248_abnormal_Harderian_gland0.92850834
103MP0010386_abnormal_urinary_bladder0.92799956
104MP0001697_abnormal_embryo_size0.92666800
105MP0000631_abnormal_neuroendocrine_gland0.91956841
106MP0008058_abnormal_DNA_repair0.91944106
107MP0002116_abnormal_craniofacial_bone0.91778733
108MP0002396_abnormal_hematopoietic_system0.91545928
109MP0009250_abnormal_appendicular_skeleto0.91203491
110MP0001145_abnormal_male_reproductive0.89625436
111MP0000733_abnormal_muscle_development0.89384426
112MP0005645_abnormal_hypothalamus_physiol0.88553267
113MP0000428_abnormal_craniofacial_morphol0.87624714
114MP0001879_abnormal_lymphatic_vessel0.87274255
115MP0003943_abnormal_hepatobiliary_system0.87213214
116MP0002638_abnormal_pupillary_reflex0.86499327
117MP0008569_lethality_at_weaning0.86406174
118MP0001784_abnormal_fluid_regulation0.86292842
119MP0002572_abnormal_emotion/affect_behav0.84722721
120MP0002086_abnormal_extraembryonic_tissu0.83634613
121MP0001502_abnormal_circadian_rhythm0.83059829
122MP0004957_abnormal_blastocyst_morpholog0.83052480
123MP0002114_abnormal_axial_skeleton0.82140355
124MP0002081_perinatal_lethality0.81611752
125MP0000579_abnormal_nail_morphology0.79305386
126MP0003880_abnormal_central_pattern0.79069435
127MP0002249_abnormal_larynx_morphology0.77690122
128MP0009780_abnormal_chondrocyte_physiolo0.76354162
129MP0002184_abnormal_innervation0.75799778
130MP0008995_early_reproductive_senescence0.75300559
131MP0002233_abnormal_nose_morphology0.73337523
132MP0005395_other_phenotype0.72875484
133MP0002161_abnormal_fertility/fecundity0.72831340
134MP0002970_abnormal_white_adipose0.72816803
135MP0002152_abnormal_brain_morphology0.72152545
136MP0004145_abnormal_muscle_electrophysio0.71947261
137MP0002109_abnormal_limb_morphology0.71750295
138MP0002925_abnormal_cardiovascular_devel0.71334551
139MP0003045_fibrosis0.70688954
140MP0005621_abnormal_cell_physiology0.70687487
141MP0001188_hyperpigmentation0.70478034
142MP0002735_abnormal_chemical_nociception0.69766608
143MP0003385_abnormal_body_wall0.69639499
144MP0001486_abnormal_startle_reflex0.69206390
145MP0009703_decreased_birth_body0.69158738
146MP0000266_abnormal_heart_morphology0.68782508
147MP0009672_abnormal_birth_weight0.65007961
148MP0000639_abnormal_adrenal_gland0.64958954
149MP0001501_abnormal_sleep_pattern0.64355295
150MP0003091_abnormal_cell_migration0.63344901
151MP0003698_abnormal_male_reproductive0.63083400
152MP0004924_abnormal_behavior0.61840829

Predicted human phenotypes

RankGene SetZ-score
1Papillary thyroid carcinoma (HP:0002895)4.91686721
2Abnormality of the fingertips (HP:0001211)4.22763180
3Abnormality of the left ventricular outflow tract (HP:0011103)3.67039405
4Subaortic stenosis (HP:0001682)3.67039405
5Chromsome breakage (HP:0040012)3.67022090
6Chromosomal breakage induced by crosslinking agents (HP:0003221)3.46387126
7Dysmetric saccades (HP:0000641)3.38855406
8Facial hemangioma (HP:0000329)3.36649180
9Volvulus (HP:0002580)3.10466708
10Shawl scrotum (HP:0000049)2.94588727
11Abnormality of the labia minora (HP:0012880)2.93572970
12Thyroid carcinoma (HP:0002890)2.88403120
13Lip pit (HP:0100267)2.83930151
14Genetic anticipation (HP:0003743)2.73003882
15Male infertility (HP:0003251)2.65909685
16Acute myeloid leukemia (HP:0004808)2.61765512
17Prostate neoplasm (HP:0100787)2.61720469
18Hyperkalemia (HP:0002153)2.48960601
19Exercise-induced myalgia (HP:0003738)2.48918758
20Flat capital femoral epiphysis (HP:0003370)2.46603402
21Cystic hygroma (HP:0000476)2.44493287
22Capillary hemangiomas (HP:0005306)2.39996641
23Ectopic kidney (HP:0000086)2.37971380
24Papilledema (HP:0001085)2.34249761
25Long clavicles (HP:0000890)2.30550212
26Patellar aplasia (HP:0006443)2.30333641
27Focal motor seizures (HP:0011153)2.28853018
28Nemaline bodies (HP:0003798)2.24965911
29Urethral obstruction (HP:0000796)2.24665734
30Muscle fiber inclusion bodies (HP:0100299)2.22614839
31Ankle clonus (HP:0011448)2.19006408
32Progressive cerebellar ataxia (HP:0002073)2.18867701
33Arterial tortuosity (HP:0005116)2.18130484
34Abnormality of chromosome segregation (HP:0002916)2.17744714
35Termporal pattern (HP:0011008)2.16996392
36Insidious onset (HP:0003587)2.16996392
37Long eyelashes (HP:0000527)2.16922340
38Febrile seizures (HP:0002373)2.15121499
39Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.15077023
40Thick eyebrow (HP:0000574)2.14668112
41Macroorchidism (HP:0000053)2.13298726
42Overlapping toe (HP:0001845)2.12913185
43Neonatal hypoglycemia (HP:0001998)2.11161918
44Obsessive-compulsive behavior (HP:0000722)2.10090981
45Abnormal hair whorl (HP:0010721)2.09717398
46Sandal gap (HP:0001852)2.07866571
47Narrow palate (HP:0000189)2.07203317
48Submucous cleft hard palate (HP:0000176)2.07053587
49Aplasia/Hypoplasia of the patella (HP:0006498)2.04831827
50Dislocated radial head (HP:0003083)2.03731055
51Tapered finger (HP:0001182)2.03048986
52Cubitus valgus (HP:0002967)2.03022671
53Oligodactyly (hands) (HP:0001180)2.02358058
54Abnormality of the phalanges of the hallux (HP:0010057)2.02240432
55Birth length less than 3rd percentile (HP:0003561)2.01061786
56Bowel incontinence (HP:0002607)2.00921737
57Transitional cell carcinoma of the bladder (HP:0006740)2.00556942
58Abnormality of the intervertebral disk (HP:0005108)2.00066109
59Low anterior hairline (HP:0000294)1.99201678
60Hepatoblastoma (HP:0002884)1.94992046
61Insulin-resistant diabetes mellitus (HP:0000831)1.94672928
62Slow saccadic eye movements (HP:0000514)1.94494648
63Prominent nose (HP:0000448)1.94470159
64Deep palmar crease (HP:0006191)1.94133846
65Midline defect of the nose (HP:0004122)1.92824910
66Deeply set eye (HP:0000490)1.92268517
67Oligodactyly (HP:0012165)1.90926589
68Aplasia/Hypoplasia of the uvula (HP:0010293)1.90355981
69Truncal obesity (HP:0001956)1.90329403
70EMG: neuropathic changes (HP:0003445)1.89466647
71Open mouth (HP:0000194)1.86009143
72Heterotopia (HP:0002282)1.85987076
73Abnormality of the nasal septum (HP:0000419)1.84604475
74Bladder neoplasm (HP:0009725)1.84428667
75Bladder carcinoma (HP:0002862)1.84428667
76Abnormality of the radial head (HP:0003995)1.83553562
77Broad thumb (HP:0011304)1.83256421
78Abnormality of chromosome stability (HP:0003220)1.83204703
79Centrally nucleated skeletal muscle fibers (HP:0003687)1.82581909
80Thickened calvaria (HP:0002684)1.82398086
81Broad palm (HP:0001169)1.82115717
82Enlarged penis (HP:0000040)1.81554351
83Vascular tortuosity (HP:0004948)1.81169502
84Cortical dysplasia (HP:0002539)1.80457197
85Abnormality of the aortic arch (HP:0012303)1.79164849
86Hammertoe (HP:0001765)1.78274917
87Trigonocephaly (HP:0000243)1.78015742
88Spondylolisthesis (HP:0003302)1.77930983
89Postural instability (HP:0002172)1.77837537
90Hypoplastic iliac wings (HP:0002866)1.77143146
91Supranuclear gaze palsy (HP:0000605)1.76911124
92Leiomyosarcoma (HP:0100243)1.75806000
93Uterine leiomyosarcoma (HP:0002891)1.75806000
94Drooling (HP:0002307)1.74944040
95Excessive salivation (HP:0003781)1.74944040
96Abnormality of incisor morphology (HP:0011063)1.74302271
97Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.73696515
98Short 4th metacarpal (HP:0010044)1.73696515
99Urinary bladder sphincter dysfunction (HP:0002839)1.73440765
100Abnormality of the columella (HP:0009929)1.72745984
101EEG with generalized epileptiform discharges (HP:0011198)1.72082148
102Hypsarrhythmia (HP:0002521)1.71672477
103Fatigue (HP:0012378)1.71431372
104Impaired smooth pursuit (HP:0007772)1.71409373
105Cutis marmorata (HP:0000965)1.70459763
106Meckel diverticulum (HP:0002245)1.70080416
107Abnormal large intestine physiology (HP:0012700)1.69992499
108Abnormality of the ischium (HP:0003174)1.68580540
109Truncal ataxia (HP:0002078)1.67191957
110Inappropriate behavior (HP:0000719)1.67035888
111Protruding tongue (HP:0010808)1.66932069
112Difficulty running (HP:0009046)1.66927933
113Relative macrocephaly (HP:0004482)1.66687099
114Abnormality of the carotid arteries (HP:0005344)1.66587355
115Gaze-evoked nystagmus (HP:0000640)1.66479635
116Epileptic encephalopathy (HP:0200134)1.66412305
117Mask-like facies (HP:0000298)1.65794856
118Curly hair (HP:0002212)1.65242841
119Gastroesophageal reflux (HP:0002020)1.65234961
120Decreased number of peripheral myelinated nerve fibers (HP:0003380)1.65212080
121Epileptiform EEG discharges (HP:0011182)1.65125769
122Highly arched eyebrow (HP:0002553)1.64779509
123Low posterior hairline (HP:0002162)1.64740005
124Germ cell neoplasia (HP:0100728)1.64620724
125Peripheral hypomyelination (HP:0007182)1.64221807
126Thickened helices (HP:0000391)1.64157720
127Oligodontia (HP:0000677)1.63231284
128Complete atrioventricular canal defect (HP:0001674)1.63071549
129Hypoplastic labia majora (HP:0000059)1.61545376
130Abnormality of skeletal muscle fiber size (HP:0012084)1.60908353
131Abnormality of the distal phalanx of the thumb (HP:0009617)1.59979102
132Menstrual irregularities (HP:0000858)1.59595636
133Aplasia/Hypoplasia of the sternum (HP:0006714)1.59410713
134Molar tooth sign on MRI (HP:0002419)1.59162183
135Abnormality of midbrain morphology (HP:0002418)1.59162183
136Large earlobe (HP:0009748)1.59135136
137Tracheomalacia (HP:0002779)1.58562403
138Impaired social interactions (HP:0000735)1.58529765
139Abnormal social behavior (HP:0012433)1.58529765
140Bundle branch block (HP:0011710)1.58368280
141Sparse lateral eyebrow (HP:0005338)1.58051287
142Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.57999679
143Abnormality of ocular smooth pursuit (HP:0000617)1.57933204
144Neoplasm of the oral cavity (HP:0100649)1.57903341
145Clubbing of toes (HP:0100760)1.57788146
146Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.57449817
147Vertebral arch anomaly (HP:0008438)1.56667000
148Increased number of teeth (HP:0011069)1.55410668
149Pancreatic fibrosis (HP:0100732)1.55105319
150Microglossia (HP:0000171)1.54866911
151Abnormality of the labia majora (HP:0012881)1.54724479
152Genu recurvatum (HP:0002816)1.54344997
153Obstructive sleep apnea (HP:0002870)1.53660971
154Abnormality of the preputium (HP:0100587)1.53123336
155Abnormality of the ileum (HP:0001549)1.53111844
156Widely spaced teeth (HP:0000687)1.52886965
157Hyperglycemia (HP:0003074)1.52881293
158Hip dysplasia (HP:0001385)1.52513032
159Deep philtrum (HP:0002002)1.49710511
160Adrenal hypoplasia (HP:0000835)1.49110860
161Absent frontal sinuses (HP:0002688)1.48713430
162Atonic seizures (HP:0010819)1.46720007
163Hip contracture (HP:0003273)1.46611708
164Breast aplasia (HP:0100783)1.46434318
165Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.46211263
166Focal seizures (HP:0007359)1.45470111
167Primary amenorrhea (HP:0000786)1.45179602
168Acute lymphatic leukemia (HP:0006721)1.43705822
169Fetal akinesia sequence (HP:0001989)1.43474047
170Absent eyebrow (HP:0002223)1.43195486
171Myelodysplasia (HP:0002863)1.42861851
172Abnormality of the labia (HP:0000058)1.42762644
173Hypoplastic ischia (HP:0003175)1.42660272

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LATS15.10602906
2LATS24.16483353
3CDK123.49780689
4MAP3K63.00472183
5STK38L2.91692682
6CDC72.65037343
7ICK2.53902305
8MAP3K42.49001703
9PLK42.39110702
10TAOK12.33076759
11CDK82.29162557
12MAP3K92.28261545
13KSR22.01358088
14STK31.95147020
15PRKD31.94182024
16TAOK31.93324579
17DMPK1.75920930
18MAP2K71.70784275
19MAP3K71.69009934
20RAF11.68631804
21ERBB41.68249554
22STK381.62101628
23KSR11.61353066
24WNK11.59834051
25NTRK21.54277705
26PAK61.50062064
27CHEK21.45749619
28NTRK31.44794982
29MUSK1.36082190
30CDK91.34089927
31CDK61.30616463
32TYRO31.29467169
33MAP3K101.29029680
34SGK21.25501745
35OBSCN1.25060004
36NEK21.21021734
37MELK1.18890926
38EEF2K1.16785747
39MAP3K131.16015439
40MAPK131.13657126
41CAMK1D1.12710555
42MAP4K21.12703741
43ACVR1B1.11293287
44NEK61.10065701
45YES11.10018080
46SGK31.08411299
47UHMK11.07368324
48CAMK41.06867408
49NUAK11.03679839
50PASK1.03244704
51TTK1.03165532
52BRAF1.03083946
53CAMK1G1.02345217
54PLK21.02190513
55FGFR41.02127280
56MAPK121.01188376
57MAP2K40.99852631
58TRPM70.99511759
59CDK30.97847087
60RET0.90855777
61TRIB30.90487156
62EPHA40.87968246
63MAP3K140.87919014
64SIK20.87209241
65SIK30.86570573
66MARK20.85606954
67RIPK40.85472888
68RPS6KB10.84244851
69CHEK10.82108267
70SCYL20.81817196
71PDGFRB0.80667748
72STK240.78608759
73PRKD20.75168048
74ATM0.74716668
75PRKAA10.74343933
76TTN0.73822389
77MAPK100.73163680
78MARK10.72806769
79MAPK110.72775887
80BCR0.71766920
81FRK0.71096412
82CASK0.68533004
83CAMKK10.65732485
84SIK10.65517158
85STK110.65211214
86PLK30.61514893
87FGFR30.59485502
88PKN20.57365201
89PLK10.55114171
90MTOR0.54710834
91MAP3K50.54319629
92MAPK90.53671810
93SGK2230.52814938
94SGK4940.52814938
95PDGFRA0.52800645
96CHUK0.52677816
97PRKCH0.52213318
98FGFR20.52177497
99SGK10.51733203
100CDK20.51731792
101MAPK140.50657213
102MAPK70.50089472
103DYRK20.49826099
104BRD40.49481977
105BMPR20.48215384
106CAMKK20.47272500
107CDK10.46986469
108EPHA30.45997524
109GSK3B0.45905104
110JAK30.45426369
111MAP2K30.45190032
112PRKAA20.45112104
113BRSK10.44889043
114MAP2K60.43968530
115PHKG20.43899190
116PHKG10.43899190
117CDK50.42868039
118FGFR10.42582623
119PDK10.40942914
120MAPK10.40784415
121CSNK1E0.40705621
122DYRK1A0.39252922
123CDK40.38266926
124CSNK1G20.36940123
125ABL10.36637408
126AKT30.36187286
127HIPK20.35945357
128RPS6KA40.35371886
129ATR0.35305602
130ERBB30.34705020
131AURKB0.34635762
132PRPF4B0.34397694
133MARK30.33712395
134ABL20.33627167
135CDK70.32818798
136SRPK10.32634016
137NLK0.30703600
138MAP3K20.30443422
139RPS6KA30.30062131
140AKT10.29519124
141MAPK80.28543734

Predicted pathways (KEGG)

RankGene SetZ-score
1Basal transcription factors_Homo sapiens_hsa030221.70554512
2Cell cycle_Homo sapiens_hsa041101.67779508
3Circadian rhythm_Homo sapiens_hsa047101.62006934
4Pancreatic cancer_Homo sapiens_hsa052121.61645128
5Dorso-ventral axis formation_Homo sapiens_hsa043201.60508574
6Acute myeloid leukemia_Homo sapiens_hsa052211.57457429
7Long-term potentiation_Homo sapiens_hsa047201.47372596
8Colorectal cancer_Homo sapiens_hsa052101.44504531
9Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.41940675
10Nicotine addiction_Homo sapiens_hsa050331.41649865
11Prolactin signaling pathway_Homo sapiens_hsa049171.40523533
12Endometrial cancer_Homo sapiens_hsa052131.35466519
13mTOR signaling pathway_Homo sapiens_hsa041501.32443508
14GnRH signaling pathway_Homo sapiens_hsa049121.29042610
15Oocyte meiosis_Homo sapiens_hsa041141.27819681
16RNA degradation_Homo sapiens_hsa030181.26745098
17Type II diabetes mellitus_Homo sapiens_hsa049301.26481730
18MicroRNAs in cancer_Homo sapiens_hsa052061.25810156
19Choline metabolism in cancer_Homo sapiens_hsa052311.25112611
20Olfactory transduction_Homo sapiens_hsa047401.24997716
21Adherens junction_Homo sapiens_hsa045201.23062091
22Thyroid hormone signaling pathway_Homo sapiens_hsa049191.22700544
23Insulin resistance_Homo sapiens_hsa049311.21405640
24Glioma_Homo sapiens_hsa052141.18477686
25Renal cell carcinoma_Homo sapiens_hsa052111.18384132
26AMPK signaling pathway_Homo sapiens_hsa041521.17467952
27ErbB signaling pathway_Homo sapiens_hsa040121.16523707
28TGF-beta signaling pathway_Homo sapiens_hsa043501.13858201
29Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.12514336
30Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.12257393
31FoxO signaling pathway_Homo sapiens_hsa040681.12247903
32Chronic myeloid leukemia_Homo sapiens_hsa052201.11522949
33Ovarian steroidogenesis_Homo sapiens_hsa049131.10896565
34B cell receptor signaling pathway_Homo sapiens_hsa046621.10514079
35Amphetamine addiction_Homo sapiens_hsa050311.09736026
36Phosphatidylinositol signaling system_Homo sapiens_hsa040701.09650368
37Non-small cell lung cancer_Homo sapiens_hsa052231.06729873
38Glutamatergic synapse_Homo sapiens_hsa047241.05799431
39Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.05592482
40mRNA surveillance pathway_Homo sapiens_hsa030151.04554100
41Dopaminergic synapse_Homo sapiens_hsa047281.03900271
42Cholinergic synapse_Homo sapiens_hsa047251.03700633
43Longevity regulating pathway - mammal_Homo sapiens_hsa042111.02952975
44Circadian entrainment_Homo sapiens_hsa047131.02727924
45Glucagon signaling pathway_Homo sapiens_hsa049221.01534439
46cAMP signaling pathway_Homo sapiens_hsa040241.01126980
47Insulin secretion_Homo sapiens_hsa049111.00886423
48Estrogen signaling pathway_Homo sapiens_hsa049151.00118371
49Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.00086339
50Oxytocin signaling pathway_Homo sapiens_hsa049210.99954972
51Aldosterone synthesis and secretion_Homo sapiens_hsa049250.99917138
52Fanconi anemia pathway_Homo sapiens_hsa034600.97651222
53Long-term depression_Homo sapiens_hsa047300.97144365
54Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.96004300
55Neurotrophin signaling pathway_Homo sapiens_hsa047220.95084837
56p53 signaling pathway_Homo sapiens_hsa041150.94155170
57MAPK signaling pathway_Homo sapiens_hsa040100.93776590
58VEGF signaling pathway_Homo sapiens_hsa043700.93459815
59Morphine addiction_Homo sapiens_hsa050320.93253316
60Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.92287610
61Cocaine addiction_Homo sapiens_hsa050300.89104426
62cGMP-PKG signaling pathway_Homo sapiens_hsa040220.88812569
63Hepatitis B_Homo sapiens_hsa051610.88633084
64Wnt signaling pathway_Homo sapiens_hsa043100.88050376
65Sphingolipid signaling pathway_Homo sapiens_hsa040710.87985687
66Prostate cancer_Homo sapiens_hsa052150.87774908
67Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.87218504
68Hippo signaling pathway_Homo sapiens_hsa043900.84250655
69Notch signaling pathway_Homo sapiens_hsa043300.83616322
70Synaptic vesicle cycle_Homo sapiens_hsa047210.82692645
71Serotonergic synapse_Homo sapiens_hsa047260.81461365
72Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.79601549
73Adipocytokine signaling pathway_Homo sapiens_hsa049200.78199913
74HIF-1 signaling pathway_Homo sapiens_hsa040660.78006073
75Ras signaling pathway_Homo sapiens_hsa040140.77701300
76HTLV-I infection_Homo sapiens_hsa051660.76631555
77Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.76620829
78RNA transport_Homo sapiens_hsa030130.76591120
79Small cell lung cancer_Homo sapiens_hsa052220.75298888
80Inositol phosphate metabolism_Homo sapiens_hsa005620.75188765
81Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.74913702
82Phospholipase D signaling pathway_Homo sapiens_hsa040720.74421261
83T cell receptor signaling pathway_Homo sapiens_hsa046600.74227700
84TNF signaling pathway_Homo sapiens_hsa046680.74151460
85Taste transduction_Homo sapiens_hsa047420.73329288
86Melanoma_Homo sapiens_hsa052180.72541044
87GABAergic synapse_Homo sapiens_hsa047270.72265006
88Salivary secretion_Homo sapiens_hsa049700.71296915
89Proteoglycans in cancer_Homo sapiens_hsa052050.70348164
90Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.69609493
91Chemokine signaling pathway_Homo sapiens_hsa040620.69567923
92Dilated cardiomyopathy_Homo sapiens_hsa054140.68636160
93Herpes simplex infection_Homo sapiens_hsa051680.68615390
94Melanogenesis_Homo sapiens_hsa049160.66952991
95Renin secretion_Homo sapiens_hsa049240.66664729
96Thyroid cancer_Homo sapiens_hsa052160.66019685
97Regulation of actin cytoskeleton_Homo sapiens_hsa048100.65309733
98Carbohydrate digestion and absorption_Homo sapiens_hsa049730.65173718
99Fatty acid biosynthesis_Homo sapiens_hsa000610.63242352
100Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.63110138
101Lysine degradation_Homo sapiens_hsa003100.62743816
102Rap1 signaling pathway_Homo sapiens_hsa040150.62354153
103AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.62076968
104Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.61797616
105Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.61616601
106Gap junction_Homo sapiens_hsa045400.61243981
107Transcriptional misregulation in cancer_Homo sapiens_hsa052020.60952111
108Central carbon metabolism in cancer_Homo sapiens_hsa052300.60591091
109Viral carcinogenesis_Homo sapiens_hsa052030.60570624
110Insulin signaling pathway_Homo sapiens_hsa049100.60093327
111Vascular smooth muscle contraction_Homo sapiens_hsa042700.60067055
112Measles_Homo sapiens_hsa051620.59745337
113Calcium signaling pathway_Homo sapiens_hsa040200.58101510
114Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.58055234
115Gastric acid secretion_Homo sapiens_hsa049710.57838752
116Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.57547362
117Osteoclast differentiation_Homo sapiens_hsa043800.56297634
118Pathways in cancer_Homo sapiens_hsa052000.56274412
119Focal adhesion_Homo sapiens_hsa045100.55797743
120Hepatitis C_Homo sapiens_hsa051600.55757893
121Jak-STAT signaling pathway_Homo sapiens_hsa046300.52223132

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »