FPR3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cellular response to interferon-alpha (GO:0035457)7.58254410
2neutrophil activation involved in immune response (GO:0002283)6.62311514
3positive regulation of natural killer cell differentiation (GO:0032825)6.57927052
4antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G6.19614129
5regulation of RIG-I signaling pathway (GO:0039535)6.06232515
6positive regulation of type 2 immune response (GO:0002830)5.65855879
7glycosphingolipid catabolic process (GO:0046479)5.64041011
8regulation of mononuclear cell migration (GO:0071675)5.45182501
9negative regulation of interleukin-12 production (GO:0032695)5.34962204
10oligosaccharide catabolic process (GO:0009313)5.27540237
11cellular response to thyroid hormone stimulus (GO:0097067)5.26926136
12cellular response to type I interferon (GO:0071357)5.23245289
13type I interferon signaling pathway (GO:0060337)5.23245289
14response to interferon-alpha (GO:0035455)5.20452634
15regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)5.10699102
16response to type I interferon (GO:0034340)5.09696010
17glycolipid catabolic process (GO:0019377)5.08670703
18production of molecular mediator involved in inflammatory response (GO:0002532)5.01953870
19regulation of natural killer cell differentiation (GO:0032823)4.98953310
20striated muscle atrophy (GO:0014891)4.72161979
21neutrophil activation (GO:0042119)4.60246610
22positive regulation of interferon-alpha production (GO:0032727)4.59534047
23positive regulation of toll-like receptor signaling pathway (GO:0034123)4.57124348
24granulocyte activation (GO:0036230)4.56964270
25ceramide catabolic process (GO:0046514)4.53795942
26positive regulation by symbiont of host defense response (GO:0052509)4.51427957
27modulation by symbiont of host defense response (GO:0052031)4.51427957
28modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.51427957
29modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.51427957
30positive regulation by organism of defense response of other organism involved in symbiotic interact4.51427957
31modulation by symbiont of host immune response (GO:0052553)4.51427957
32lipopolysaccharide-mediated signaling pathway (GO:0031663)4.49750586
33natural killer cell mediated immunity (GO:0002228)4.41175529
34natural killer cell mediated cytotoxicity (GO:0042267)4.41175529
35regulation of macrophage chemotaxis (GO:0010758)4.37594641
36positive regulation of interleukin-17 production (GO:0032740)4.37509014
37positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)4.33234892
38regulation of activation of Janus kinase activity (GO:0010533)4.32215466
39regulation of chemokine biosynthetic process (GO:0045073)4.30619159
40amino sugar catabolic process (GO:0046348)4.29613684
41regulation of interferon-alpha production (GO:0032647)4.25438432
42natural killer cell differentiation (GO:0001779)4.24328519
43response to peptidoglycan (GO:0032494)4.21306558
44positive regulation of T cell cytokine production (GO:0002726)4.17521309
45hydrogen peroxide biosynthetic process (GO:0050665)4.15820645
46skeletal muscle adaptation (GO:0043501)4.10726538
47positive regulation of mast cell activation (GO:0033005)4.10295279
48muscle atrophy (GO:0014889)4.04186680
49response to thyroid hormone (GO:0097066)4.04126142
50negative regulation of viral genome replication (GO:0045071)3.97984715
51positive regulation of chemokine biosynthetic process (GO:0045080)3.95292090
52regulation of interferon-beta biosynthetic process (GO:0045357)3.94878899
53macrophage activation involved in immune response (GO:0002281)3.89973582
54regulation of cholesterol storage (GO:0010885)3.88086044
55positive regulation of leukocyte degranulation (GO:0043302)3.85442990
56positive regulation of gamma-delta T cell activation (GO:0046645)3.84856000
57regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)3.84731926
58regulation of natural killer cell activation (GO:0032814)3.83103177
59regulation of defense response to virus by host (GO:0050691)3.82259613
60membrane lipid catabolic process (GO:0046466)3.78331176
61N-acetylneuraminate metabolic process (GO:0006054)3.78095591
62neutrophil mediated immunity (GO:0002446)3.76556756
63regulation of syncytium formation by plasma membrane fusion (GO:0060142)3.72589892
64positive regulation of monocyte chemotaxis (GO:0090026)3.72077376
65positive regulation of mast cell degranulation (GO:0043306)3.71153184
66positive regulation of mast cell activation involved in immune response (GO:0033008)3.71153184
67defense response to virus (GO:0051607)3.70347635
68detection of molecule of bacterial origin (GO:0032490)3.69309780
69reactive oxygen species biosynthetic process (GO:1903409)3.66299775
70positive regulation of heat generation (GO:0031652)3.61325817
71leukocyte aggregation (GO:0070486)3.60370009
72regulation of fever generation (GO:0031620)3.59090542
73positive regulation of natural killer cell activation (GO:0032816)3.58352707
74positive regulation of response to biotic stimulus (GO:0002833)3.58201648
75positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.57602415
76sphingolipid catabolic process (GO:0030149)3.53937743
77eosinophil chemotaxis (GO:0048245)3.53703393
78respiratory burst (GO:0045730)3.53455751
79positive regulation of cellular amide metabolic process (GO:0034250)3.53155609
80regulation of hypersensitivity (GO:0002883)3.51911813
81myeloid cell activation involved in immune response (GO:0002275)3.51424826
82leukocyte mediated cytotoxicity (GO:0001909)3.51396790
83response to host immune response (GO:0052572)3.51132993
84response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.51132993
85defense response to protozoan (GO:0042832)3.50967273
86regulation of mast cell degranulation (GO:0043304)3.50918328
87cellular extravasation (GO:0045123)3.50582098
88positive regulation of T cell migration (GO:2000406)3.47958986
89regulation of T-helper 2 cell differentiation (GO:0045628)3.46262058
90immunoglobulin mediated immune response (GO:0016064)3.45383157
91positive regulation of interferon-beta production (GO:0032728)3.41970776
92response to vitamin D (GO:0033280)3.41515605
93lymphocyte chemotaxis (GO:0048247)3.38497290
94monocyte chemotaxis (GO:0002548)3.38172664
95interferon-gamma-mediated signaling pathway (GO:0060333)3.37337093
96positive regulation of cAMP-mediated signaling (GO:0043950)3.36914807
97T-helper 1 type immune response (GO:0042088)3.35590068
98positive regulation of acute inflammatory response (GO:0002675)3.32045610
99response to manganese ion (GO:0010042)3.31580605
100regulation of immunoglobulin secretion (GO:0051023)3.31063769
101superoxide anion generation (GO:0042554)3.30150919
102regulation of mast cell activation involved in immune response (GO:0033006)3.30054324
103positive regulation of interleukin-12 production (GO:0032735)3.28899755
104cellular response to lipopolysaccharide (GO:0071222)3.28681171
105positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.27167887
106natural killer cell activation (GO:0030101)3.27026605
107regulation of mast cell activation (GO:0033003)3.26808624
108cellular response to vitamin D (GO:0071305)3.25918319
109positive regulation of myeloid leukocyte mediated immunity (GO:0002888)3.24508346
110barbed-end actin filament capping (GO:0051016)3.23158594
111positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.23093091
112regulation of leukocyte degranulation (GO:0043300)3.22322361
113apoptotic cell clearance (GO:0043277)3.22196271
114detection of other organism (GO:0098543)3.20409314
115positive regulation of T-helper cell differentiation (GO:0045624)3.20174973
116positive regulation of antigen processing and presentation (GO:0002579)3.18180984
117T cell migration (GO:0072678)3.16480805
118eosinophil migration (GO:0072677)3.14136544
119negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.13258601
120negative regulation of translation, ncRNA-mediated (GO:0040033)3.13258601
121regulation of translation, ncRNA-mediated (GO:0045974)3.13258601
122detection of external biotic stimulus (GO:0098581)3.13033881
123response to host defenses (GO:0052200)3.13011166
124response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.13011166
125response to host (GO:0075136)3.13011166
126negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.12108837
127cellular response to molecule of bacterial origin (GO:0071219)3.11328163
128myeloid dendritic cell differentiation (GO:0043011)3.11094430
129B cell mediated immunity (GO:0019724)3.10978484
130regulation of interleukin-17 production (GO:0032660)3.10913413
131fat-soluble vitamin biosynthetic process (GO:0042362)3.10642897
132cellular response to zinc ion (GO:0071294)3.10109181
133cellular response to interferon-gamma (GO:0071346)3.09776607
134regulation of monocyte chemotaxis (GO:0090025)3.06530467
135positive regulation of cholesterol efflux (GO:0010875)2.98503678
136regulation of vitamin D biosynthetic process (GO:0060556)2.98470098
137positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.98296180
138macrophage differentiation (GO:0030225)2.97418300
139regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.94334903
140regulation of T cell tolerance induction (GO:0002664)2.94067583
141regulation of myeloid leukocyte mediated immunity (GO:0002886)2.93073732
142phagosome maturation (GO:0090382)2.91550484
143regulation of antigen processing and presentation (GO:0002577)2.90761471
144regulation of podosome assembly (GO:0071801)2.90697999
145adhesion of symbiont to host cell (GO:0044650)2.89930335
146virion attachment to host cell (GO:0019062)2.89930335
147macrophage activation (GO:0042116)2.89246356
148negative regulation of interleukin-17 production (GO:0032700)2.88444635
149myeloid dendritic cell activation (GO:0001773)2.87191532
150negative regulation of nitric oxide biosynthetic process (GO:0045019)2.86826067
151negative regulation of cell killing (GO:0031342)2.85631268
152negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.85631268
153negative regulation of myeloid cell apoptotic process (GO:0033033)2.81886952
154peptide catabolic process (GO:0043171)2.81596760
155protein localization to endosome (GO:0036010)2.81002091
156pinocytosis (GO:0006907)2.80439677
157keratan sulfate catabolic process (GO:0042340)2.80011245
158low-density lipoprotein particle remodeling (GO:0034374)2.79336444
159NIK/NF-kappaB signaling (GO:0038061)2.76469016
160regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.75796835
161positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610812.73586558
162detection of bacterium (GO:0016045)2.73265320
163detection of biotic stimulus (GO:0009595)2.73185662
164cellular response to ethanol (GO:0071361)2.70967511
165negative regulation of erythrocyte differentiation (GO:0045647)2.70590282
166intracellular pH reduction (GO:0051452)2.67916699
167positive regulation of macrophage cytokine production (GO:0060907)2.67901871
168regulation of dendritic cell antigen processing and presentation (GO:0002604)2.67736071

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human8.05081334
2IRF8_21731497_ChIP-ChIP_J774_Mouse7.27098227
3IRF1_21803131_ChIP-Seq_MONOCYTES_Human7.23668275
4BP1_19119308_ChIP-ChIP_Hs578T_Human6.75105593
5GATA1_22025678_ChIP-Seq_K562_Human5.13051385
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.53547964
7IRF8_27001747_Chip-Seq_BMDM_Mouse4.12202101
8FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.49516081
9NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.18384080
10RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human3.08756085
11SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.04747476
12Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.98059712
13STAT4_19710469_ChIP-ChIP_TH1__Mouse2.71274518
14TP63_17297297_ChIP-ChIP_HaCaT_Human2.57869261
15STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.57334369
16SPI1_23127762_ChIP-Seq_K562_Human2.40796638
17STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.40792737
18SMAD_19615063_ChIP-ChIP_OVARY_Human2.36594246
19MYB_21317192_ChIP-Seq_ERMYB_Mouse2.30117614
20CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.99038233
21MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.97242641
22SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.87582731
23STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.84553417
24BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.78494231
25GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.77843423
26VDR_21846776_ChIP-Seq_THP-1_Human1.71746227
27NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.69870690
28TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.62382090
29TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.58313943
30EGR1_23403033_ChIP-Seq_LIVER_Mouse1.58110932
31EGR1_19374776_ChIP-ChIP_THP-1_Human1.57811838
32MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.52870114
33TFEB_21752829_ChIP-Seq_HELA_Human1.44514499
34LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.37234313
35ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.36345470
36E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.35896006
37SPI1_23547873_ChIP-Seq_NB4_Human1.34314322
38LXR_22292898_ChIP-Seq_THP-1_Human1.34012457
39CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.32241756
40GATA1_19941827_ChIP-Seq_MEL_Mouse1.29959747
41CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.27856087
42SOX2_20726797_ChIP-Seq_SW620_Human1.26857312
43GATA3_26560356_Chip-Seq_TH2_Human1.26375632
44EGR1_19032775_ChIP-ChIP_M12_Human1.25400390
45TRIM28_21343339_ChIP-Seq_HEK293_Human1.25234499
46STAT6_21828071_ChIP-Seq_BEAS2B_Human1.24735405
47KDM2B_26808549_Chip-Seq_SUP-B15_Human1.21744729
48PU_27001747_Chip-Seq_BMDM_Mouse1.21019669
49PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.19061224
50CDX2_19796622_ChIP-Seq_MESCs_Mouse1.13633819
51CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.13531031
52TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.12133774
53* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10895887
54CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.09520512
55CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.09280751
56BRD4_27068464_Chip-Seq_AML-cells_Mouse1.07622991
57FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.05733077
58MYB_26560356_Chip-Seq_TH2_Human1.05540187
59STAT1_20625510_ChIP-Seq_HELA_Human1.05028581
60BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.03725026
61NRF2_20460467_ChIP-Seq_MEFs_Mouse1.03282931
62NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.03282931
63SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.02496784
64ELK3_25401928_ChIP-Seq_HUVEC_Human1.02378715
65SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.02296625
66NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.00224444
67LXR_22158963_ChIP-Seq_LIVER_Mouse0.96284609
68PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.96150591
69FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.93756613
70VDR_24787735_ChIP-Seq_THP-1_Human0.92654503
71FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.92603586
72RARG_19884340_ChIP-ChIP_MEFs_Mouse0.92374869
73GATA1_22383799_ChIP-Seq_G1ME_Mouse0.92324395
74CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.89854557
75PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.88851596
76TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.87895789
77GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.87790604
78* GATA2_19941826_ChIP-Seq_K562_Human0.85536787
79TCF7_22412390_ChIP-Seq_EML_Mouse0.83018111
80ESR2_21235772_ChIP-Seq_MCF-7_Human0.82926634
81CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.81640434
82PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.80934891
83KDM2B_26808549_Chip-Seq_DND41_Human0.80887239
84MYB_26560356_Chip-Seq_TH1_Human0.78494353
85UTX_26944678_Chip-Seq_JUKART_Human0.77794158
86CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.77365825
87BCL6_27268052_Chip-Seq_Bcells_Human0.76990208
88PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.76740972
89RXR_22158963_ChIP-Seq_LIVER_Mouse0.76740876
90SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.75823999
91VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.75281318
92THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.75126146
93GATA2_21666600_ChIP-Seq_HMVEC_Human0.75090885
94CDX2_20551321_ChIP-Seq_CACO-2_Human0.73934698
95ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.73241680
96KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.73121803
97BCOR_27268052_Chip-Seq_Bcells_Human0.71510557
98RUNX1_22412390_ChIP-Seq_EML_Mouse0.70933218
99SCL_19346495_ChIP-Seq_HPC-7_Human0.70425168
100MAF_26560356_Chip-Seq_TH1_Human0.69136187
101GATA3_27048872_Chip-Seq_THYMUS_Human0.69068447
102CJUN_26792858_Chip-Seq_BT549_Human0.67834601
103* SMRT_27268052_Chip-Seq_Bcells_Human0.67476080
104GATA3_21867929_ChIP-Seq_TH1_Mouse0.66265225
105GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.65941254
106NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.64389766
107SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.64161110
108* GATA1_19941826_ChIP-Seq_K562_Human0.63532634
109LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.62881468
110RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.62417015
111FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.61620052
112IGF1R_20145208_ChIP-Seq_DFB_Human0.60982569
113CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.60229621
114RUNX_20019798_ChIP-Seq_JUKART_Human0.59733658
115GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.58018673
116TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.56837357
117* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.55894883
118EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.55501383
119P63_26484246_Chip-Seq_KERATINOCYTES_Human0.54955319
120VDR_24763502_ChIP-Seq_THP-1_Human0.54429657
121GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.53571569
122SMAD1_18555785_Chip-Seq_ESCs_Mouse0.53089088
123SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.52728214
124RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.52350759
125TP63_23658742_ChIP-Seq_EP156T_Human0.51919872
126IKZF1_21737484_ChIP-ChIP_HCT116_Human0.51641341
127SPI1_20517297_ChIP-Seq_HL60_Human0.51253728
128KAP1_22055183_ChIP-Seq_ESCs_Mouse0.51031245
129GATA2_22383799_ChIP-Seq_G1ME_Mouse0.50295143
130PPARA_22158963_ChIP-Seq_LIVER_Mouse0.49130086
131* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.48125585
132RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.47712155
133CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.47646350

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003724_increased_susceptibility_to4.95231687
2MP0009785_altered_susceptibility_to4.86797905
3MP0002148_abnormal_hypersensitivity_rea3.96074706
4MP0006082_CNS_inflammation3.56173995
5MP0003303_peritoneal_inflammation3.37581782
6MP0001835_abnormal_antigen_presentation3.22219114
7MP0005387_immune_system_phenotype3.12984485
8MP0001790_abnormal_immune_system3.12984485
9MP0005025_abnormal_response_to3.08016755
10MP0005000_abnormal_immune_tolerance3.02767926
11MP0002419_abnormal_innate_immunity2.88875830
12MP0002139_abnormal_hepatobiliary_system2.76123176
13MP0003075_altered_response_to2.67177833
14MP0003436_decreased_susceptibility_to2.65943941
15MP0000685_abnormal_immune_system2.53814114
16MP0002723_abnormal_immune_serum2.39240055
17MP0001800_abnormal_humoral_immune2.39055101
18MP0004782_abnormal_surfactant_physiolog2.32944139
19MP0002452_abnormal_antigen_presenting2.30260503
20MP0008004_abnormal_stomach_pH2.23660895
21MP0009764_decreased_sensitivity_to2.23585568
22MP0003300_gastrointestinal_ulcer2.20326316
23MP0005058_abnormal_lysosome_morphology2.14596439
24MP0005671_abnormal_response_to2.08602896
25MP0005166_decreased_susceptibility_to2.06786566
26MP0009278_abnormal_bone_marrow2.06651644
27MP0004858_abnormal_nervous_system2.05802586
28MP0001348_abnormal_lacrimal_gland1.99643740
29MP0001819_abnormal_immune_cell1.97268937
30MP0002163_abnormal_gland_morphology1.96678273
31MP0001533_abnormal_skeleton_physiology1.87471814
32MP0004947_skin_inflammation1.85594412
33MP0000604_amyloidosis1.84496967
34MP0002420_abnormal_adaptive_immunity1.83899959
35MP0002277_abnormal_respiratory_mucosa1.78336547
36MP0003448_altered_tumor_morphology1.77740731
37MP0001845_abnormal_inflammatory_respons1.76360960
38MP0005451_abnormal_body_composition1.68304210
39MP0005164_abnormal_response_to1.67548855
40MP0004510_myositis1.66879411
41MP0008469_abnormal_protein_level1.66141731
42MP0003329_amyloid_beta_deposits1.62130330
43MP0001346_abnormal_lacrimal_gland1.59464175
44MP0005167_abnormal_blood-brain_barrier1.50909789
45MP0005464_abnormal_platelet_physiology1.50813038
46MP0001545_abnormal_hematopoietic_system1.47483580
47MP0005397_hematopoietic_system_phenotyp1.47483580
48MP0003690_abnormal_glial_cell1.43725631
49MP0002254_reproductive_system_inflammat1.43466225
50MP0003191_abnormal_cellular_cholesterol1.41708842
51MP0003172_abnormal_lysosome_physiology1.39464404
52MP0009333_abnormal_splenocyte_physiolog1.36186094
53MP0002138_abnormal_hepatobiliary_system1.36183531
54MP0000343_altered_response_to1.35184665
55MP0003183_abnormal_peptide_metabolism1.34580193
56MP0010155_abnormal_intestine_physiology1.34351194
57MP0000858_altered_metastatic_potential1.31509453
58MP0002332_abnormal_exercise_endurance1.23704050
59MP0005365_abnormal_bile_salt1.23482586
60MP0005310_abnormal_salivary_gland1.23147880
61MP0001501_abnormal_sleep_pattern1.21539588
62MP0003045_fibrosis1.21202397
63MP0005379_endocrine/exocrine_gland_phen1.20091686
64MP0000716_abnormal_immune_system1.17342480
65MP0002877_abnormal_melanocyte_morpholog1.14447788
66MP0001853_heart_inflammation1.13809113
67MP0002998_abnormal_bone_remodeling1.10850096
68MP0002006_tumorigenesis1.10728691
69MP0009763_increased_sensitivity_to1.09299734
70MP0002405_respiratory_system_inflammati1.08666091
71MP0000920_abnormal_myelination1.06429882
72MP0006054_spinal_hemorrhage1.05299604
73MP0009840_abnormal_foam_cell1.02131310
74MP0001881_abnormal_mammary_gland1.01475470
75MP0008260_abnormal_autophagy0.98434026
76MP0000569_abnormal_digit_pigmentation0.97442185
77MP0003806_abnormal_nucleotide_metabolis0.96521592
78MP0000371_diluted_coat_color0.94911443
79MP0002398_abnormal_bone_marrow0.94132334
80MP0005257_abnormal_intraocular_pressure0.94125962
81MP0008775_abnormal_heart_ventricle0.91492851
82MP0005390_skeleton_phenotype0.86793353
83MP0003279_aneurysm0.86052930
84MP0004019_abnormal_vitamin_homeostasis0.84933228
85MP0003186_abnormal_redox_activity0.84137535
86MP0010352_gastrointestinal_tract_polyps0.83824145
87MP0005647_abnormal_sex_gland0.81811518
88MP0002429_abnormal_blood_cell0.81197829
89MP0003795_abnormal_bone_structure0.81194389
90MP0003656_abnormal_erythrocyte_physiolo0.80025482
91MP0005535_abnormal_body_temperature0.78423333
92MP0000383_abnormal_hair_follicle0.77204734
93MP0003634_abnormal_glial_cell0.76940112
94MP0005165_increased_susceptibility_to0.75613733
95MP0000465_gastrointestinal_hemorrhage0.72627430
96MP0003632_abnormal_nervous_system0.72359224
97MP0010678_abnormal_skin_adnexa0.70456994
98MP0003453_abnormal_keratinocyte_physiol0.70294601
99MP0003091_abnormal_cell_migration0.68335593
100MP0000015_abnormal_ear_pigmentation0.67565500
101MP0001764_abnormal_homeostasis0.66591776
102MP0003195_calcinosis0.66509251
103MP0002136_abnormal_kidney_physiology0.65259760
104MP0002736_abnormal_nociception_after0.64579520
105MP0000689_abnormal_spleen_morphology0.64546763
106MP0010307_abnormal_tumor_latency0.63819937
107MP0002837_dystrophic_cardiac_calcinosis0.63390800
108MP0001663_abnormal_digestive_system0.63103077
109MP0005319_abnormal_enzyme/_coenzyme0.62895292
110MP0010234_abnormal_vibrissa_follicle0.62784055
111MP0003633_abnormal_nervous_system0.62760875
112MP0002722_abnormal_immune_system0.62714824
113MP0008874_decreased_physiological_sensi0.62230221
114MP0000609_abnormal_liver_physiology0.61931900
115MP0003566_abnormal_cell_adhesion0.61862588
116MP0009115_abnormal_fat_cell0.61796497
117MP0005595_abnormal_vascular_smooth0.61681739
118MP0001851_eye_inflammation0.60794904
119MP0001542_abnormal_bone_strength0.60732350
120MP0002928_abnormal_bile_duct0.58917098
121MP0002295_abnormal_pulmonary_circulatio0.56733990
122MP0002693_abnormal_pancreas_physiology0.56581295
123MP0005332_abnormal_amino_acid0.56460121
124MP0003828_pulmonary_edema0.54903917
125MP0005584_abnormal_enzyme/coenzyme_acti0.52842374
126MP0005084_abnormal_gallbladder_morpholo0.50043479
127MP0000249_abnormal_blood_vessel0.49584771
128MP0002090_abnormal_vision0.49027485
129MP0004883_abnormal_blood_vessel0.47710027
130MP0000627_abnormal_mammary_gland0.46903135

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of glycolipid metabolism (HP:0010969)8.86219709
2Abnormality of liposaccharide metabolism (HP:0010968)8.86219709
3Abnormality of glycosphingolipid metabolism (HP:0004343)8.86219709
4Eczematoid dermatitis (HP:0000976)7.74911065
5Recurrent bacterial skin infections (HP:0005406)7.38518206
6Recurrent abscess formation (HP:0002722)7.26868393
7Recurrent gram-negative bacterial infections (HP:0005420)7.14974535
8Increased IgM level (HP:0003496)7.09075903
9Autoimmune thrombocytopenia (HP:0001973)6.52395167
10Mediastinal lymphadenopathy (HP:0100721)6.03385818
11Increased cerebral lipofuscin (HP:0011813)6.02878157
12Dysostosis multiplex (HP:0000943)5.08550412
13Pustule (HP:0200039)5.06805644
14Gingivitis (HP:0000230)4.96743514
15Abnormality of macrophages (HP:0004311)4.94152399
16Loss of speech (HP:0002371)4.64911397
17Stomatitis (HP:0010280)4.61509986
18Periodontitis (HP:0000704)4.54208070
19Mutism (HP:0002300)4.05218354
20Thick nail (HP:0001805)4.03760366
21Abnormality of glycosaminoglycan metabolism (HP:0004371)3.97364104
22Abnormality of mucopolysaccharide metabolism (HP:0011020)3.97364104
23Abnormality of polysaccharide metabolism (HP:0011012)3.97364104
24Recurrent skin infections (HP:0001581)3.89479978
25Mucopolysacchariduria (HP:0008155)3.84812132
26Urinary glycosaminoglycan excretion (HP:0003541)3.84812132
27Autoimmune hemolytic anemia (HP:0001890)3.84058397
28Chronic obstructive pulmonary disease (HP:0006510)3.76234228
29Obstructive lung disease (HP:0006536)3.76234228
30Poor head control (HP:0002421)3.60154289
31Hypergammaglobulinemia (HP:0010702)3.57177489
32Cellulitis (HP:0100658)3.46924573
33Abnormality of the vasculature of the conjunctiva (HP:0008054)3.33057084
34Myocardial infarction (HP:0001658)3.24323223
35Vasculitis (HP:0002633)3.24095143
36Urticaria (HP:0001025)3.22101202
37Recurrent fungal infections (HP:0002841)3.21108117
38Recurrent viral infections (HP:0004429)3.20526557
39Glomerulonephritis (HP:0000099)3.10622440
40Osteolytic defects of the hand bones (HP:0009699)3.10273769
41Osteolytic defects of the phalanges of the hand (HP:0009771)3.10273769
42Basal ganglia calcification (HP:0002135)3.08050115
43Tetraparesis (HP:0002273)3.07659728
44Elevated erythrocyte sedimentation rate (HP:0003565)3.05613786
45Hematochezia (HP:0002573)2.98110859
46Thin bony cortex (HP:0002753)2.96445366
47Axonal loss (HP:0003447)2.94344528
48Spastic tetraparesis (HP:0001285)2.92825418
49Premature loss of primary teeth (HP:0006323)2.88880953
50Diminished motivation (HP:0000745)2.86337060
51Apathy (HP:0000741)2.85982453
52Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.85062575
53Parakeratosis (HP:0001036)2.84751611
54Gastrointestinal infarctions (HP:0005244)2.84187259
55Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.83380468
56Nuclear cataract (HP:0100018)2.77014040
57Enlarged epiphyses (HP:0010580)2.74345372
58Retinal atrophy (HP:0001105)2.73203329
59Cerebral inclusion bodies (HP:0100314)2.71764710
60Neuronal loss in central nervous system (HP:0002529)2.71741290
61Agnosia (HP:0010524)2.71408211
62Interstitial pulmonary disease (HP:0006530)2.69924535
63Upper motor neuron abnormality (HP:0002127)2.67136656
64Disinhibition (HP:0000734)2.63586190
65Orchitis (HP:0100796)2.63413392
66Joint swelling (HP:0001386)2.63262421
67Gingival bleeding (HP:0000225)2.60437151
68Purpura (HP:0000979)2.60180800
69Inappropriate behavior (HP:0000719)2.55539893
70Retrobulbar optic neuritis (HP:0100654)2.55133262
71Optic neuritis (HP:0100653)2.55133262
72Metaphyseal irregularity (HP:0003025)2.54510198
73Hepatosplenomegaly (HP:0001433)2.53509355
74Cheilitis (HP:0100825)2.52756896
75Spontaneous hematomas (HP:0007420)2.52366892
76Recurrent pneumonia (HP:0006532)2.51832767
77Complement deficiency (HP:0004431)2.49124531
78Abnormality of the periventricular white matter (HP:0002518)2.46111475
79Subacute progressive viral hepatitis (HP:0006572)2.46018799
80IgA deficiency (HP:0002720)2.43590703
81Vacuolated lymphocytes (HP:0001922)2.43208743
82Myositis (HP:0100614)2.42508835
83Abnormality of T cell number (HP:0011839)2.41329214
84Osteomyelitis (HP:0002754)2.39403865
85Global brain atrophy (HP:0002283)2.38959298
86Progressive neurologic deterioration (HP:0002344)2.35455902
87Increased serum ferritin (HP:0003281)2.34317119
88Delayed epiphyseal ossification (HP:0002663)2.31468157
89Systemic lupus erythematosus (HP:0002725)2.29547385
90Bone pain (HP:0002653)2.29027397
91Eosinophilia (HP:0001880)2.28947430
92Esophageal neoplasm (HP:0100751)2.27305457
93Neoplasm of head and neck (HP:0012288)2.27305457
94Pulmonary infiltrates (HP:0002113)2.25651694
95Neutropenia (HP:0001875)2.23812905
96Abnormality of the costochondral junction (HP:0000919)2.21790517
97Hemoptysis (HP:0002105)2.21088843
98Leukocytosis (HP:0001974)2.20690909
99Chronic sinusitis (HP:0011109)2.19712072
100Dementia (HP:0000726)2.19495179
101Recurrent lower respiratory tract infections (HP:0002783)2.18436846
102Asymmetric septal hypertrophy (HP:0001670)2.17392104
103Neurofibrillary tangles (HP:0002185)2.16803388
104Micronodular cirrhosis (HP:0001413)2.15425558
105Cerebral hemorrhage (HP:0001342)2.15000889
106Hypochromic anemia (HP:0001931)2.14914313
107Cardiomegaly (HP:0001640)2.14146778
108Widely patent fontanelles and sutures (HP:0004492)2.14114047
109Abnormality of iron homeostasis (HP:0011031)2.13086988
110Peripheral demyelination (HP:0011096)2.12713235
111Amyloidosis (HP:0011034)2.12593378
112Porencephaly (HP:0002132)2.10861025
113Personality changes (HP:0000751)2.10749666
114Xanthomatosis (HP:0000991)2.06890008
115Abnormality of T cell physiology (HP:0011840)2.05893613
116Polyneuropathy (HP:0001271)2.05811803
117Recurrent cutaneous fungal infections (HP:0011370)2.05156097
118Chronic mucocutaneous candidiasis (HP:0002728)2.05156097
119Absent frontal sinuses (HP:0002688)2.03175125
120Sepsis (HP:0100806)2.02604333
121Progressive visual loss (HP:0000529)2.01979452
122Skin ulcer (HP:0200042)2.00074198
123Thoracic kyphosis (HP:0002942)1.97797460
124Pathologic fracture (HP:0002756)1.97706883
125Abnormality of complement system (HP:0005339)1.97244672
126Conjunctival telangiectasia (HP:0000524)1.97160815
127Cleft eyelid (HP:0000625)1.97102444
128Increased CSF protein (HP:0002922)1.95417251
129Prolonged neonatal jaundice (HP:0006579)1.94439944
130Meningitis (HP:0001287)1.91356106
131Abnormality of eosinophils (HP:0001879)1.89701313
132T lymphocytopenia (HP:0005403)1.87896739
133Protuberant abdomen (HP:0001538)1.87099150
134Lower limb hyperreflexia (HP:0002395)1.86937537
135Mitral stenosis (HP:0001718)1.86657652
136Abnormality of transition element cation homeostasis (HP:0011030)1.86563560
137Malnutrition (HP:0004395)1.86291822
138Granulocytopenia (HP:0001913)1.85747331
139Palmoplantar hyperkeratosis (HP:0000972)1.85086934
140Abnormality of the common coagulation pathway (HP:0010990)1.84624273
141Congenital sensorineural hearing impairment (HP:0008527)1.83459923
142Fair hair (HP:0002286)1.82025359
143Multiple enchondromatosis (HP:0005701)1.81937416
144Prostate neoplasm (HP:0100787)1.80777683
145Peritonitis (HP:0002586)1.80515519
146Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.80247235
147Abnormality of T cells (HP:0002843)1.78990935
148Memory impairment (HP:0002354)1.78189665
149Petechiae (HP:0000967)1.78065133
150Abnormality of cells of the lymphoid lineage (HP:0012140)1.77651559
151Increased neuronal autofluorescent lipopigment (HP:0002074)1.77312500
152Increased IgE level (HP:0003212)1.77241496
153Joint hemorrhage (HP:0005261)1.76709977
154Homocystinuria (HP:0002156)1.75441366
155Abnormality of homocysteine metabolism (HP:0010919)1.75441366
156Polycythemia (HP:0001901)1.74830461
157Hypophosphatemia (HP:0002148)1.74560208
158Esophageal varix (HP:0002040)1.73727109
159Stroke (HP:0001297)1.73417436
160Supranuclear gaze palsy (HP:0000605)1.73387088
161Hypokinesia (HP:0002375)1.72711445
162Arthralgia (HP:0002829)1.72216412
163Acrocyanosis (HP:0001063)1.68542513
164Abnormality of the prostate (HP:0008775)1.68033203
165Mucosal telangiectasiae (HP:0100579)1.67015282
166Keratoconjunctivitis sicca (HP:0001097)1.66730196
167Restrictive lung disease (HP:0002091)1.63482111

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PBK7.67682422
2MAP3K145.15650083
3RIPK44.90680055
4TYK23.50253483
5TGFBR23.03414252
6IRAK32.91186088
7JAK32.80598885
8JAK12.73715910
9ACVR1B2.71489673
10DDR22.61906570
11BLK2.55557328
12TBK12.48110626
13IKBKE2.29777592
14FGFR42.19034203
15IRAK42.16898288
16CSK2.04548859
17CAMKK21.99095437
18IKBKB1.91818136
19BCR1.71015128
20CAMK1D1.68335392
21EPHA31.67306026
22FGR1.66864523
23CSF1R1.64133281
24DAPK21.61090339
25CDC42BPA1.55751443
26TAOK21.49140575
27EPHB11.47382595
28STK41.43998182
29FRK1.40496924
30TXK1.32773126
31EIF2AK21.32174076
32MAP3K31.30843641
33EIF2AK11.30687416
34FGFR31.29368433
35PDK21.27442978
36ERBB31.26407564
37MATK1.22166998
38MAP2K31.18081390
39SYK1.17798956
40MAP3K131.16010458
41MST41.13025739
42CHUK1.12129240
43RPS6KA41.11100837
44YES11.10991794
45MOS1.05135436
46TAOK11.04818667
47MAP4K11.04065760
48HCK1.02601438
49BMPR21.02355184
50RIPK11.01045013
51JAK21.00595062
52LYN0.98574279
53CDK60.94888225
54TESK20.93907711
55PRPF4B0.92977503
56PLK20.89085507
57CAMK1G0.88843759
58LCK0.85789345
59CCNB10.85491964
60ADRBK20.82983686
61ZAP700.81834510
62TGFBR10.80554704
63KIT0.78304215
64MARK30.77020204
65TAOK30.76864151
66PRKCD0.75511751
67TEC0.75146015
68ERN10.72519364
69RPS6KA20.68124039
70PRKCQ0.66539850
71TESK10.65381019
72BTK0.65233129
73FYN0.64699191
74IRAK20.62150095
75PIK3CA0.62100253
76RPS6KC10.60714481
77RPS6KL10.60714481
78MAPK110.59544582
79CAMKK10.59438766
80TTN0.59075039
81LIMK10.58875619
82PAK40.58514813
83TYRO30.57931806
84PDGFRA0.56668077
85CSNK1A1L0.55553757
86GRK70.54680812
87RPS6KA50.54678611
88NME20.53074420
89NEK60.52077124
90TRPM70.51497187
91PDPK10.50935586
92PRKCE0.50816272
93RPS6KA60.48266575
94ARAF0.47915068
95ALK0.47444328
96MAP2K60.47388131
97PIM20.45593351
98MAP3K110.44763293
99MST1R0.44138440
100ERBB40.40912251
101EPHB20.40808585
102ABL10.40647901
103PRKG20.39041694
104ABL20.38530116
105ADRBK10.38230987
106MAP3K50.36927221
107MAP3K100.36739441
108CDK40.36489318
109KSR10.35225447
110MAPK70.35180537
111STK240.34930874
112NLK0.34846921
113MAPK40.34404658
114PDGFRB0.33665579
115EGFR0.33366613
116SIK30.32694291
117IRAK10.31378864
118IGF1R0.31352426
119MAP3K20.30983271
120MAPK120.30882282
121KSR20.30747565
122NTRK10.30489752
123PIM10.29044090
124SRC0.28539391
125PDK10.25202593
126PKN10.24706261
127DAPK30.23824897
128MAP3K80.23702176
129STK100.22586599
130MAP3K120.22400084
131NEK90.20976936
132DAPK10.20006578
133CDK90.19184708
134MINK10.18602034
135PRKACG0.17771848
136MAP3K10.17262767
137BMPR1B0.15517880
138INSR0.14286069
139FES0.13731605
140PRKCA0.12931110
141ITK0.11911916
142MAPKAPK20.11391997
143PRKCZ0.10775448

Predicted pathways (KEGG)

RankGene SetZ-score
1Other glycan degradation_Homo sapiens_hsa005114.34760003
2Graft-versus-host disease_Homo sapiens_hsa053324.33255685
3Allograft rejection_Homo sapiens_hsa053303.67972873
4Cytosolic DNA-sensing pathway_Homo sapiens_hsa046233.45654419
5Intestinal immune network for IgA production_Homo sapiens_hsa046723.24069912
6Leishmaniasis_Homo sapiens_hsa051403.20610259
7Toll-like receptor signaling pathway_Homo sapiens_hsa046203.12219426
8* Staphylococcus aureus infection_Homo sapiens_hsa051503.07993125
9RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.98403073
10Glycosaminoglycan degradation_Homo sapiens_hsa005312.93839203
11NOD-like receptor signaling pathway_Homo sapiens_hsa046212.70122579
12NF-kappa B signaling pathway_Homo sapiens_hsa040642.67108259
13Type I diabetes mellitus_Homo sapiens_hsa049402.66374821
14African trypanosomiasis_Homo sapiens_hsa051432.44710549
15Influenza A_Homo sapiens_hsa051642.44391915
16Measles_Homo sapiens_hsa051622.43289938
17Malaria_Homo sapiens_hsa051442.36732314
18Pertussis_Homo sapiens_hsa051332.35395417
19Rheumatoid arthritis_Homo sapiens_hsa053232.34291732
20Legionellosis_Homo sapiens_hsa051342.34116797
21Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.31437017
22TNF signaling pathway_Homo sapiens_hsa046682.17767403
23Autoimmune thyroid disease_Homo sapiens_hsa053202.00790612
24Asthma_Homo sapiens_hsa053101.97713472
25Herpes simplex infection_Homo sapiens_hsa051681.89402435
26Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.82944047
27Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.54293976
28Osteoclast differentiation_Homo sapiens_hsa043801.52517147
29Tuberculosis_Homo sapiens_hsa051521.50850302
30Salmonella infection_Homo sapiens_hsa051321.41050040
31Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.40770676
32Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.40147881
33Toxoplasmosis_Homo sapiens_hsa051451.35233621
34Prion diseases_Homo sapiens_hsa050201.33511090
35Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.33173718
36Viral myocarditis_Homo sapiens_hsa054161.28130513
37Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.25123030
38Hepatitis C_Homo sapiens_hsa051601.23459596
39Phagosome_Homo sapiens_hsa041451.15515893
40Chemokine signaling pathway_Homo sapiens_hsa040621.15365309
41Steroid biosynthesis_Homo sapiens_hsa001001.09945479
42Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.08135521
43Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.08088323
44Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.07486148
45Amoebiasis_Homo sapiens_hsa051461.06262070
46Apoptosis_Homo sapiens_hsa042101.04986931
47Jak-STAT signaling pathway_Homo sapiens_hsa046301.04971049
48Hematopoietic cell lineage_Homo sapiens_hsa046400.99676849
49Arginine biosynthesis_Homo sapiens_hsa002200.93387500
50Hepatitis B_Homo sapiens_hsa051610.93360802
51Sphingolipid metabolism_Homo sapiens_hsa006000.89678648
52Pentose and glucuronate interconversions_Homo sapiens_hsa000400.87858802
53AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.80302087
54Vibrio cholerae infection_Homo sapiens_hsa051100.80084560
55Primary immunodeficiency_Homo sapiens_hsa053400.79556328
56Lysosome_Homo sapiens_hsa041420.76111315
57Primary bile acid biosynthesis_Homo sapiens_hsa001200.73372380
58Galactose metabolism_Homo sapiens_hsa000520.67703838
59Bladder cancer_Homo sapiens_hsa052190.66306529
60Folate biosynthesis_Homo sapiens_hsa007900.61626428
61Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.58018452
62Small cell lung cancer_Homo sapiens_hsa052220.56099065
63B cell receptor signaling pathway_Homo sapiens_hsa046620.55499348
64Complement and coagulation cascades_Homo sapiens_hsa046100.55132563
65Shigellosis_Homo sapiens_hsa051310.51488760
66Leukocyte transendothelial migration_Homo sapiens_hsa046700.50502360
67Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.49069380
68Dorso-ventral axis formation_Homo sapiens_hsa043200.47052967
69Adipocytokine signaling pathway_Homo sapiens_hsa049200.38837451
70Synaptic vesicle cycle_Homo sapiens_hsa047210.37388003
71Notch signaling pathway_Homo sapiens_hsa043300.34292634
72HIF-1 signaling pathway_Homo sapiens_hsa040660.34232308
73Tryptophan metabolism_Homo sapiens_hsa003800.34076886
74Endocytosis_Homo sapiens_hsa041440.32930995
75SNARE interactions in vesicular transport_Homo sapiens_hsa041300.31946933
76Prolactin signaling pathway_Homo sapiens_hsa049170.31738422
77Peroxisome_Homo sapiens_hsa041460.31191203
78Neurotrophin signaling pathway_Homo sapiens_hsa047220.30730070
79Type II diabetes mellitus_Homo sapiens_hsa049300.30592912
80Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.29704498
81VEGF signaling pathway_Homo sapiens_hsa043700.29628600
82Fructose and mannose metabolism_Homo sapiens_hsa000510.28290536
83Mineral absorption_Homo sapiens_hsa049780.27689012
84Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.27351684
85Insulin resistance_Homo sapiens_hsa049310.27214445
86Arginine and proline metabolism_Homo sapiens_hsa003300.26720059
87Starch and sucrose metabolism_Homo sapiens_hsa005000.25601543
88Sphingolipid signaling pathway_Homo sapiens_hsa040710.25393323
89Epstein-Barr virus infection_Homo sapiens_hsa051690.24280881
90Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.23831500
91Renal cell carcinoma_Homo sapiens_hsa052110.22859642
92Glutathione metabolism_Homo sapiens_hsa004800.22532662
93Transcriptional misregulation in cancer_Homo sapiens_hsa052020.21949809
94Vitamin digestion and absorption_Homo sapiens_hsa049770.21657736
95Pancreatic cancer_Homo sapiens_hsa052120.21121772
96Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.20652125
97Antigen processing and presentation_Homo sapiens_hsa046120.20128834
98Sulfur metabolism_Homo sapiens_hsa009200.18096206
99Platelet activation_Homo sapiens_hsa046110.17632343
100Phospholipase D signaling pathway_Homo sapiens_hsa040720.17237910
101GnRH signaling pathway_Homo sapiens_hsa049120.17173709
102Renin-angiotensin system_Homo sapiens_hsa046140.16773006
103Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.15417330
104Viral carcinogenesis_Homo sapiens_hsa052030.15272040
105Proteasome_Homo sapiens_hsa030500.14627031
106HTLV-I infection_Homo sapiens_hsa051660.14283458
107Histidine metabolism_Homo sapiens_hsa003400.12785431
108Vitamin B6 metabolism_Homo sapiens_hsa007500.12128173
109Pentose phosphate pathway_Homo sapiens_hsa000300.10462380
110Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.09332023
111p53 signaling pathway_Homo sapiens_hsa041150.08770284
112Collecting duct acid secretion_Homo sapiens_hsa049660.08437228
113Acute myeloid leukemia_Homo sapiens_hsa052210.07933269
114Carbohydrate digestion and absorption_Homo sapiens_hsa049730.07531229
115Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.06885377
116FoxO signaling pathway_Homo sapiens_hsa040680.04280603
117Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.03973315
118Ether lipid metabolism_Homo sapiens_hsa005650.03472421
119Systemic lupus erythematosus_Homo sapiens_hsa053220.02443714
120T cell receptor signaling pathway_Homo sapiens_hsa046600.02232990
121Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.01551865
122Chronic myeloid leukemia_Homo sapiens_hsa05220-0.0259825
123* Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080-0.0187140
124PPAR signaling pathway_Homo sapiens_hsa03320-0.0172365

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »