FRMPD3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1postsynaptic membrane organization (GO:0001941)5.79664035
2presynaptic membrane assembly (GO:0097105)5.15521726
3behavioral response to nicotine (GO:0035095)4.85443135
4presynaptic membrane organization (GO:0097090)4.40543232
5neuronal action potential propagation (GO:0019227)4.32552456
6respiratory chain complex IV assembly (GO:0008535)4.25117414
7fucose catabolic process (GO:0019317)4.11439395
8L-fucose metabolic process (GO:0042354)4.11439395
9L-fucose catabolic process (GO:0042355)4.11439395
10facial nerve structural organization (GO:0021612)4.11184956
11pyrimidine nucleobase catabolic process (GO:0006208)4.03328112
12cytochrome complex assembly (GO:0017004)4.00487631
13gamma-aminobutyric acid transport (GO:0015812)4.00265599
14transmission of nerve impulse (GO:0019226)3.92569965
15positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.82650791
16negative regulation of cytosolic calcium ion concentration (GO:0051481)3.79811137
17dendritic spine morphogenesis (GO:0060997)3.75699344
18epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.74873204
19response to pheromone (GO:0019236)3.71210282
20protein localization to synapse (GO:0035418)3.70563734
21neuron cell-cell adhesion (GO:0007158)3.56277789
22membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.56020527
23nucleobase catabolic process (GO:0046113)3.53215094
24regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.46546788
25water-soluble vitamin biosynthetic process (GO:0042364)3.46248939
26neurotransmitter-gated ion channel clustering (GO:0072578)3.43790773
27generation of neurons (GO:0048699)3.42240401
28DNA deamination (GO:0045006)3.38383018
29positive regulation of synaptic transmission, GABAergic (GO:0032230)3.37047076
30regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.31624764
31proline transport (GO:0015824)3.31292903
32cranial nerve structural organization (GO:0021604)3.21421617
33glycerophospholipid catabolic process (GO:0046475)3.20052204
34G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.18073594
35synaptic transmission, cholinergic (GO:0007271)3.17853634
36vocalization behavior (GO:0071625)3.17223985
37regulation of neurotransmitter uptake (GO:0051580)3.15458047
38protein heterotetramerization (GO:0051290)3.14422050
39epithelial cilium movement (GO:0003351)3.11089170
40righting reflex (GO:0060013)3.10312078
41detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.10125458
42ionotropic glutamate receptor signaling pathway (GO:0035235)3.07049822
43mannosylation (GO:0097502)3.06313791
44regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.03756803
45axon ensheathment in central nervous system (GO:0032291)3.02345510
46central nervous system myelination (GO:0022010)3.02345510
47positive regulation of membrane potential (GO:0045838)3.00938251
48regulation of pigment cell differentiation (GO:0050932)3.00776643
49cranial nerve morphogenesis (GO:0021602)2.97612068
50negative regulation of synaptic transmission, GABAergic (GO:0032229)2.94902861
51membrane depolarization during action potential (GO:0086010)2.94239616
52neurotransmitter secretion (GO:0007269)2.92142056
53positive regulation of dendritic spine development (GO:0060999)2.90311104
54positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.86930775
55lymphoid progenitor cell differentiation (GO:0002320)2.85044802
56protein polyglutamylation (GO:0018095)2.84533422
57mature B cell differentiation (GO:0002335)2.84309623
58superoxide anion generation (GO:0042554)2.83348440
59locomotory exploration behavior (GO:0035641)2.83097267
60positive regulation of neurotransmitter secretion (GO:0001956)2.82869735
61axonal fasciculation (GO:0007413)2.81678926
62proteasome assembly (GO:0043248)2.81637466
63neuromuscular synaptic transmission (GO:0007274)2.78132754
64regulation of glutamate receptor signaling pathway (GO:1900449)2.77158914
65developmental pigmentation (GO:0048066)2.73899162
66auditory receptor cell stereocilium organization (GO:0060088)2.72443981
67regulation of respiratory system process (GO:0044065)2.69518748
68behavioral response to ethanol (GO:0048149)2.68981110
69mast cell activation (GO:0045576)2.68888420
70piRNA metabolic process (GO:0034587)2.68116669
71axoneme assembly (GO:0035082)2.67432623
72negative regulation of telomere maintenance (GO:0032205)2.67361915
73response to peptidoglycan (GO:0032494)2.67179294
74neuronal action potential (GO:0019228)2.67130153
75regulation of microtubule-based movement (GO:0060632)2.66070552
76synapse assembly (GO:0007416)2.65861531
77synaptic transmission, glutamatergic (GO:0035249)2.64833752
78regulation of cilium movement (GO:0003352)2.63290711
79kidney morphogenesis (GO:0060993)2.63095403
80cilium movement (GO:0003341)2.62283059
81regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.62203304
82cellular ketone body metabolic process (GO:0046950)2.62159155
83negative regulation of transcription by competitive promoter binding (GO:0010944)2.61169966
84atrial cardiac muscle cell action potential (GO:0086014)2.60940780
85reflex (GO:0060004)2.60812788
86regulation of synaptic vesicle exocytosis (GO:2000300)2.59855136
87dolichol-linked oligosaccharide biosynthetic process (GO:0006488)2.59452703
88inner ear receptor stereocilium organization (GO:0060122)2.58224819
89regulation of synaptic vesicle transport (GO:1902803)2.57743108
90regulation of action potential (GO:0098900)2.57587102
91protein complex biogenesis (GO:0070271)2.56633622
92regulation of short-term neuronal synaptic plasticity (GO:0048172)2.56559720
93androgen biosynthetic process (GO:0006702)2.55685991
94negative regulation of myotube differentiation (GO:0010832)2.54670674
95detection of light stimulus involved in sensory perception (GO:0050962)2.54521494
96detection of light stimulus involved in visual perception (GO:0050908)2.54521494
97glycosphingolipid biosynthetic process (GO:0006688)2.54390606
98cornea development in camera-type eye (GO:0061303)2.53604481
99negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.53519440
100positive regulation of oligodendrocyte differentiation (GO:0048714)2.53255207
101protein localization to cilium (GO:0061512)2.52838868
102omega-hydroxylase P450 pathway (GO:0097267)2.52617565
103startle response (GO:0001964)2.51514609
104central nervous system neuron axonogenesis (GO:0021955)2.51081628
105regulation of respiratory gaseous exchange (GO:0043576)2.50555458
106negative regulation of transcription regulatory region DNA binding (GO:2000678)2.50263012
107glutamate receptor signaling pathway (GO:0007215)2.50228876
108multicellular organismal signaling (GO:0035637)2.49820020
109mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.49805476
110mitochondrial respiratory chain complex I assembly (GO:0032981)2.49805476
111NADH dehydrogenase complex assembly (GO:0010257)2.49805476
112nonmotile primary cilium assembly (GO:0035058)2.49242876
113regulation of synapse structural plasticity (GO:0051823)2.48921829
114viral genome replication (GO:0019079)2.48583642
115regulation of neurotransmitter levels (GO:0001505)2.47986763
116regulation of female receptivity (GO:0045924)2.47975374
117indolalkylamine metabolic process (GO:0006586)2.47365721
118inositol phosphate catabolic process (GO:0071545)2.47289458
119spinal cord development (GO:0021510)2.47046020
120synaptic vesicle maturation (GO:0016188)2.46912742
121C-terminal protein lipidation (GO:0006501)2.46745467
122myeloid leukocyte mediated immunity (GO:0002444)2.46172889
123neuron recognition (GO:0008038)2.45687793
124retinal cone cell development (GO:0046549)2.45154148
125neurofilament cytoskeleton organization (GO:0060052)2.44443248
126positive regulation of synapse assembly (GO:0051965)2.42854141
127response to amphetamine (GO:0001975)2.41830379
128mature B cell differentiation involved in immune response (GO:0002313)2.41280751
129preassembly of GPI anchor in ER membrane (GO:0016254)2.40904797
130neurotransmitter transport (GO:0006836)2.40352355
131membrane invagination (GO:0010324)2.38954565
132somite development (GO:0061053)2.38442523
133exploration behavior (GO:0035640)2.37904928
134regulation of calcium ion-dependent exocytosis (GO:0017158)2.37370460
135regulation of rhodopsin mediated signaling pathway (GO:0022400)2.37198607
136adult walking behavior (GO:0007628)2.35815106
137regulation of synaptic transmission, GABAergic (GO:0032228)2.35668513
138C-terminal protein amino acid modification (GO:0018410)2.35105943
139positive regulation of neurotransmitter transport (GO:0051590)2.33081653
140central nervous system projection neuron axonogenesis (GO:0021952)2.31684695
141positive regulation of dendritic spine morphogenesis (GO:0061003)2.29925149
142antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.28974015
143GDP-mannose metabolic process (GO:0019673)2.28434280
144dendritic cell chemotaxis (GO:0002407)2.27876289
145negative regulation of type 2 immune response (GO:0002829)2.27681846
146CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.27457850
147centriole assembly (GO:0098534)2.27425938
148mechanosensory behavior (GO:0007638)2.27348553
149long-term memory (GO:0007616)2.26376234
150neuron-neuron synaptic transmission (GO:0007270)2.26240429
151ribosomal small subunit assembly (GO:0000028)2.25741317
152cellular response to exogenous dsRNA (GO:0071360)2.25140749
153amino sugar catabolic process (GO:0046348)2.24602268
154GPI anchor biosynthetic process (GO:0006506)2.24036793
155synaptic vesicle exocytosis (GO:0016079)2.23937882
156regulation of excitatory postsynaptic membrane potential (GO:0060079)2.23277790
157regulation of synapse assembly (GO:0051963)2.22402059
158regulation of T-helper 1 cell differentiation (GO:0045625)2.21936682
159mast cell degranulation (GO:0043303)2.21885431
160mast cell activation involved in immune response (GO:0002279)2.21885431
161defense response to protozoan (GO:0042832)2.21230832
162sympathetic nervous system development (GO:0048485)2.19333375
163nucleoside diphosphate catabolic process (GO:0009134)2.18158711
164telomere maintenance via semi-conservative replication (GO:0032201)2.16722511
165deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.16452758
166negative regulation of T-helper cell differentiation (GO:0045623)2.15638994
167negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.15638994
168mesonephros development (GO:0001823)2.13223787
169auditory behavior (GO:0031223)2.12195185
170mitochondrion degradation (GO:0000422)2.11652356
171polyketide metabolic process (GO:0030638)2.11139892
172doxorubicin metabolic process (GO:0044598)2.11139892
173daunorubicin metabolic process (GO:0044597)2.11139892
174regulation of T-helper 2 cell differentiation (GO:0045628)2.11128563
175regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.10953654
176negative regulation of viral genome replication (GO:0045071)2.10216399
177response to interferon-beta (GO:0035456)2.10017120

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human7.86482206
2GBX2_23144817_ChIP-Seq_PC3_Human3.46644609
3ZNF274_21170338_ChIP-Seq_K562_Hela3.33554825
4GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.24166992
5GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.81153528
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.75546378
7VDR_22108803_ChIP-Seq_LS180_Human2.70010266
8IGF1R_20145208_ChIP-Seq_DFB_Human2.42252389
9TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.30334024
10ZFP57_27257070_Chip-Seq_ESCs_Mouse2.25647796
11EZH2_27304074_Chip-Seq_ESCs_Mouse2.23171989
12PCGF2_27294783_Chip-Seq_ESCs_Mouse2.20777990
13SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.18095682
14FLI1_27457419_Chip-Seq_LIVER_Mouse2.12960621
15JARID2_20075857_ChIP-Seq_MESCs_Mouse2.08919777
16SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.06783651
17HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.02840872
18IKZF1_21737484_ChIP-ChIP_HCT116_Human2.00454786
19SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.91878206
20EED_16625203_ChIP-ChIP_MESCs_Mouse1.91600932
21CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.90471751
22SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.86333410
23RNF2_18974828_ChIP-Seq_MESCs_Mouse1.86305102
24EZH2_18974828_ChIP-Seq_MESCs_Mouse1.86305102
25SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.85966242
26BMI1_23680149_ChIP-Seq_NPCS_Mouse1.85597729
27SMAD_19615063_ChIP-ChIP_OVARY_Human1.78000444
28EZH2_27294783_Chip-Seq_ESCs_Mouse1.77350383
29REST_21632747_ChIP-Seq_MESCs_Mouse1.70977021
30LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.70968138
31SUZ12_27294783_Chip-Seq_NPCs_Mouse1.69068289
32SUZ12_27294783_Chip-Seq_ESCs_Mouse1.68625739
33TAF15_26573619_Chip-Seq_HEK293_Human1.68244933
34SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.67975889
35CBX2_27304074_Chip-Seq_ESCs_Mouse1.66121652
36NFE2_27457419_Chip-Seq_LIVER_Mouse1.65380456
37SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.61993219
38PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.61478060
39FUS_26573619_Chip-Seq_HEK293_Human1.61253860
40FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.58596125
41SALL1_21062744_ChIP-ChIP_HESCs_Human1.57870058
42* RNF2_27304074_Chip-Seq_ESCs_Mouse1.54320905
43ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.53898977
44BP1_19119308_ChIP-ChIP_Hs578T_Human1.53182620
45EWS_26573619_Chip-Seq_HEK293_Human1.51991492
46RNF2_27304074_Chip-Seq_NSC_Mouse1.51803263
47BCAT_22108803_ChIP-Seq_LS180_Human1.49120768
48TP53_22573176_ChIP-Seq_HFKS_Human1.48156095
49MTF2_20144788_ChIP-Seq_MESCs_Mouse1.47595389
50CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.46118443
51P53_22387025_ChIP-Seq_ESCs_Mouse1.44565720
52POU3F2_20337985_ChIP-ChIP_501MEL_Human1.43202640
53EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.42702884
54CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.41927020
55IRF8_22096565_ChIP-ChIP_GC-B_Human1.41670141
56IRF1_19129219_ChIP-ChIP_H3396_Human1.41184462
57STAT3_18555785_Chip-Seq_ESCs_Mouse1.40743298
58STAT3_23295773_ChIP-Seq_U87_Human1.40054859
59NMYC_18555785_Chip-Seq_ESCs_Mouse1.39557473
60EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.38295835
61NANOG_18555785_Chip-Seq_ESCs_Mouse1.38290139
62TCF4_23295773_ChIP-Seq_U87_Human1.37930639
63RUNX1_27457419_Chip-Seq_LIVER_Mouse1.37393685
64EZH2_27294783_Chip-Seq_NPCs_Mouse1.37289601
65MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.36997294
66SCL_19346495_ChIP-Seq_HPC-7_Human1.35564985
67E2F1_18555785_Chip-Seq_ESCs_Mouse1.35157502
68SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.34875186
69SUZ12_18555785_Chip-Seq_ESCs_Mouse1.34790570
70IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.34788211
71AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.34732516
72GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.34671983
73EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.33100904
74UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.32061144
75IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.30989514
76CBP_20019798_ChIP-Seq_JUKART_Human1.30989514
77P300_19829295_ChIP-Seq_ESCs_Human1.30405461
78SMAD3_21741376_ChIP-Seq_EPCs_Human1.28961145
79PCGF2_27294783_Chip-Seq_NPCs_Mouse1.28950496
80TOP2B_26459242_ChIP-Seq_MCF-7_Human1.28832017
81RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.28830102
82TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.28751440
83P300_18555785_Chip-Seq_ESCs_Mouse1.27350976
84PIAS1_25552417_ChIP-Seq_VCAP_Human1.26739920
85SOX2_18555785_Chip-Seq_ESCs_Mouse1.25830696
86CMYC_18555785_Chip-Seq_ESCs_Mouse1.24633101
87PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.22577169
88NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.22063587
89SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.20702933
90NR3C1_21868756_ChIP-Seq_MCF10A_Human1.19983739
91PU1_27457419_Chip-Seq_LIVER_Mouse1.19634636
92E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.19197607
93TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19160692
94POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.19160692
95TCF4_22108803_ChIP-Seq_LS180_Human1.18527037
96NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.18186499
97ETV2_25802403_ChIP-Seq_MESCs_Mouse1.17957408
98KLF5_20875108_ChIP-Seq_MESCs_Mouse1.16948312
99OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.16938271
100SMAD4_21799915_ChIP-Seq_A2780_Human1.16924034
101MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.16553026
102IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.16383283
103CTBP2_25329375_ChIP-Seq_LNCAP_Human1.16346202
104NOTCH1_21737748_ChIP-Seq_TLL_Human1.16313663
105IRF8_21731497_ChIP-ChIP_J774_Mouse1.15696754
106REST_18959480_ChIP-ChIP_MESCs_Mouse1.15473645
107LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.14920328
108CTBP1_25329375_ChIP-Seq_LNCAP_Human1.14649031
109NANOG_19829295_ChIP-Seq_ESCs_Human1.14312876
110SOX2_19829295_ChIP-Seq_ESCs_Human1.14312876
111CTCF_18555785_Chip-Seq_ESCs_Mouse1.13872296
112CDX2_19796622_ChIP-Seq_MESCs_Mouse1.13369876
113OCT4_18555785_Chip-Seq_ESCs_Mouse1.12832971
114ZFX_18555785_Chip-Seq_ESCs_Mouse1.11724846
115SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.11621000
116FOXA1_27270436_Chip-Seq_PROSTATE_Human1.11495865
117FOXA1_25329375_ChIP-Seq_VCAP_Human1.11495865
118SMAD1_18555785_Chip-Seq_ESCs_Mouse1.11034869
119ESRRB_18555785_Chip-Seq_ESCs_Mouse1.10181194
120TAL1_26923725_Chip-Seq_HPCs_Mouse1.09503240
121KLF4_18555785_Chip-Seq_ESCs_Mouse1.08347416
122RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.07318646
123SMAD4_21741376_ChIP-Seq_EPCs_Human1.07122207
124GATA3_21878914_ChIP-Seq_MCF-7_Human1.05558412
125FLI1_21867929_ChIP-Seq_TH2_Mouse1.05411162
126CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.03787552
127PRDM14_20953172_ChIP-Seq_ESCs_Human1.03099523
128NCOR_22424771_ChIP-Seq_293T_Human1.02916199
129SOX2_21211035_ChIP-Seq_LN229_Gbm1.01898975
130TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.99356663
131SMAD3_21741376_ChIP-Seq_ESCs_Human0.99129129
132MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.99063623
133DROSHA_22980978_ChIP-Seq_HELA_Human0.97047923
134ELF1_17652178_ChIP-ChIP_JURKAT_Human0.96842600
135ER_23166858_ChIP-Seq_MCF-7_Human0.96735497
136FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.95089029
137RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.94864870
138AR_25329375_ChIP-Seq_VCAP_Human0.94728907
139LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.94652927
140CRX_20693478_ChIP-Seq_RETINA_Mouse0.94625070
141MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.94025105
142FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.92122865
143KDM2B_26808549_Chip-Seq_REH_Human0.90209770
144RUNX2_22187159_ChIP-Seq_PCA_Human0.89370039
145HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.89363207

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.29888132
2MP0001188_hyperpigmentation3.76161775
3MP0006292_abnormal_olfactory_placode3.44823215
4MP0009379_abnormal_foot_pigmentation3.24725800
5MP0005409_darkened_coat_color3.10964186
6MP0000015_abnormal_ear_pigmentation2.94874046
7MP0005174_abnormal_tail_pigmentation2.88172327
8MP0003136_yellow_coat_color2.68619759
9MP0004859_abnormal_synaptic_plasticity2.65719166
10MP0002876_abnormal_thyroid_physiology2.38613217
11MP0004885_abnormal_endolymph2.33582828
12MP0001986_abnormal_taste_sensitivity2.24628915
13MP0008877_abnormal_DNA_methylation2.12671727
14MP0005423_abnormal_somatic_nervous2.09707062
15MP0001968_abnormal_touch/_nociception2.06671563
16MP0003635_abnormal_synaptic_transmissio2.02865118
17MP0009745_abnormal_behavioral_response1.99788287
18MP0006276_abnormal_autonomic_nervous1.97969383
19MP0000372_irregular_coat_pigmentation1.93508389
20MP0002638_abnormal_pupillary_reflex1.89335700
21MP0003724_increased_susceptibility_to1.83760485
22MP0006072_abnormal_retinal_apoptosis1.83757597
23MP0005075_abnormal_melanosome_morpholog1.82222209
24MP0002909_abnormal_adrenal_gland1.77787487
25MP0004381_abnormal_hair_follicle1.76905230
26MP0001835_abnormal_antigen_presentation1.75040293
27MP0008260_abnormal_autophagy1.72621778
28MP0005645_abnormal_hypothalamus_physiol1.70805774
29MP0005253_abnormal_eye_physiology1.68394427
30MP0002095_abnormal_skin_pigmentation1.67758108
31MP0002148_abnormal_hypersensitivity_rea1.67450973
32MP0009046_muscle_twitch1.65417520
33MP0002735_abnormal_chemical_nociception1.64297150
34MP0002272_abnormal_nervous_system1.63715707
35MP0009785_altered_susceptibility_to1.62269607
36MP0002822_catalepsy1.60747044
37MP0005671_abnormal_response_to1.60535122
38MP0008872_abnormal_physiological_respon1.59598079
39MP0002064_seizures1.58732202
40MP0005646_abnormal_pituitary_gland1.57891551
41MP0002734_abnormal_mechanical_nocicepti1.56741557
42MP0001486_abnormal_startle_reflex1.56612054
43MP0000681_abnormal_thyroid_gland1.56567236
44MP0004133_heterotaxia1.49313439
45MP0001529_abnormal_vocalization1.49190181
46MP0002653_abnormal_ependyma_morphology1.47713782
47MP0003011_delayed_dark_adaptation1.47068866
48MP0003195_calcinosis1.46675923
49MP0002837_dystrophic_cardiac_calcinosis1.46070510
50MP0002067_abnormal_sensory_capabilities1.44619085
51MP0005171_absent_coat_pigmentation1.44327968
52MP0002736_abnormal_nociception_after1.43283617
53MP0003879_abnormal_hair_cell1.43034670
54MP0004270_analgesia1.42958906
55MP0008569_lethality_at_weaning1.42023942
56MP0002572_abnormal_emotion/affect_behav1.39887878
57MP0002063_abnormal_learning/memory/cond1.39462915
58MP0004142_abnormal_muscle_tone1.39096500
59MP0003646_muscle_fatigue1.37799360
60MP0000955_abnormal_spinal_cord1.37434982
61MP0002557_abnormal_social/conspecific_i1.36244695
62MP0001970_abnormal_pain_threshold1.35173106
63MP0001502_abnormal_circadian_rhythm1.33927552
64MP0003122_maternal_imprinting1.33814865
65MP0001485_abnormal_pinna_reflex1.33759496
66MP0003283_abnormal_digestive_organ1.33087819
67MP0001501_abnormal_sleep_pattern1.26477182
68MP0010386_abnormal_urinary_bladder1.25589642
69MP0002751_abnormal_autonomic_nervous1.25222942
70MP0001984_abnormal_olfaction1.23808696
71MP0002928_abnormal_bile_duct1.23614812
72MP0001905_abnormal_dopamine_level1.20829121
73MP0004043_abnormal_pH_regulation1.17312935
74MP0003787_abnormal_imprinting1.16727875
75MP0005000_abnormal_immune_tolerance1.13505581
76MP0000631_abnormal_neuroendocrine_gland1.12045144
77MP0002184_abnormal_innervation1.11584959
78MP0005025_abnormal_response_to1.10972421
79MP0002733_abnormal_thermal_nociception1.10319773
80MP0002752_abnormal_somatic_nervous1.09811289
81MP0009780_abnormal_chondrocyte_physiolo1.09719972
82MP0005167_abnormal_blood-brain_barrier1.08926918
83MP0000566_synostosis1.08231456
84MP0002229_neurodegeneration1.07309888
85MP0000427_abnormal_hair_cycle1.06803624
86MP0002277_abnormal_respiratory_mucosa1.05305520
87MP0002102_abnormal_ear_morphology1.04750238
88MP0003121_genomic_imprinting1.03588147
89MP0003763_abnormal_thymus_physiology1.02317044
90MP0005499_abnormal_olfactory_system1.01292770
91MP0005394_taste/olfaction_phenotype1.01292770
92MP0002419_abnormal_innate_immunity1.00115037
93MP0002177_abnormal_outer_ear0.99667265
94MP0008995_early_reproductive_senescence0.98449698
95MP0003633_abnormal_nervous_system0.96630276
96MP0004147_increased_porphyrin_level0.96431698
97MP0004145_abnormal_muscle_electrophysio0.96052346
98MP0002066_abnormal_motor_capabilities/c0.93864951
99MP0003119_abnormal_digestive_system0.91416154
100MP0001944_abnormal_pancreas_morphology0.91005851
101MP0001963_abnormal_hearing_physiology0.90047915
102MP0002009_preneoplasia0.90000010
103MP0000026_abnormal_inner_ear0.88464211
104MP0008875_abnormal_xenobiotic_pharmacok0.88052369
105MP0008789_abnormal_olfactory_epithelium0.87615640
106MP0003436_decreased_susceptibility_to0.87246373
107MP0001819_abnormal_immune_cell0.86849537
108MP0005195_abnormal_posterior_eye0.86743048
109MP0002420_abnormal_adaptive_immunity0.86707285
110MP0002723_abnormal_immune_serum0.86542596
111MP0003938_abnormal_ear_development0.86312277
112MP0000049_abnormal_middle_ear0.84769702
113MP0002152_abnormal_brain_morphology0.83324663
114MP0003137_abnormal_impulse_conducting0.83030537
115MP0005187_abnormal_penis_morphology0.81810066
116MP0005084_abnormal_gallbladder_morpholo0.78739000
117MP0002160_abnormal_reproductive_system0.78618806
118MP0000678_abnormal_parathyroid_gland0.77805068
119MP0000230_abnormal_systemic_arterial0.76674684
120MP0002452_abnormal_antigen_presenting0.76586277
121MP0000778_abnormal_nervous_system0.76452910
122MP0002163_abnormal_gland_morphology0.76260113
123MP0002693_abnormal_pancreas_physiology0.75844695
124MP0003315_abnormal_perineum_morphology0.73872574
125MP0004742_abnormal_vestibular_system0.73364629
126MP0008058_abnormal_DNA_repair0.73059296
127MP0005551_abnormal_eye_electrophysiolog0.72862389
128MP0002938_white_spotting0.71946632
129MP0005379_endocrine/exocrine_gland_phen0.71888998
130MP0001664_abnormal_digestion0.71580000
131MP0001800_abnormal_humoral_immune0.71202476
132MP0002882_abnormal_neuron_morphology0.68471912
133MP0000569_abnormal_digit_pigmentation0.68073441
134MP0001919_abnormal_reproductive_system0.66033793
135MP0004811_abnormal_neuron_physiology0.65759331
136MP0005386_behavior/neurological_phenoty0.65648764
137MP0004924_abnormal_behavior0.65648764
138MP0001440_abnormal_grooming_behavior0.65539461
139MP0001186_pigmentation_phenotype0.64926254

Predicted human phenotypes

RankGene SetZ-score
1Type I transferrin isoform profile (HP:0003642)5.73965137
2Reduced antithrombin III activity (HP:0001976)5.66019186
3Focal motor seizures (HP:0011153)4.30668957
4Type II lissencephaly (HP:0007260)3.91354718
5Abnormal protein glycosylation (HP:0012346)3.87605556
6Abnormal glycosylation (HP:0012345)3.87605556
7Abnormal isoelectric focusing of serum transferrin (HP:0003160)3.87605556
8Abnormal protein N-linked glycosylation (HP:0012347)3.87605556
9Hypothermia (HP:0002045)3.84547566
10Nonprogressive disorder (HP:0003680)3.52379294
11Abnormality of midbrain morphology (HP:0002418)3.49564350
12Molar tooth sign on MRI (HP:0002419)3.49564350
13Nephronophthisis (HP:0000090)3.43398132
14Febrile seizures (HP:0002373)3.28099802
15Thyroid-stimulating hormone excess (HP:0002925)3.27971415
16Congenital stationary night blindness (HP:0007642)3.19120330
17Hemiparesis (HP:0001269)3.10163451
18Absent rod-and cone-mediated responses on ERG (HP:0007688)3.09836272
19Focal seizures (HP:0007359)2.90961013
20Abnormal drinking behavior (HP:0030082)2.88897829
21Polydipsia (HP:0001959)2.88897829
22Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.87540792
23Retinal dysplasia (HP:0007973)2.81775139
24Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.80899514
25Hyperventilation (HP:0002883)2.80493572
26Lissencephaly (HP:0001339)2.76550776
27Abnormality of the renal medulla (HP:0100957)2.75664362
28Medial flaring of the eyebrow (HP:0010747)2.72983523
29Chronic obstructive pulmonary disease (HP:0006510)2.70316048
30Obstructive lung disease (HP:0006536)2.70316048
31Renal Fanconi syndrome (HP:0001994)2.70256757
32Cerebellar dysplasia (HP:0007033)2.68026298
33Severe visual impairment (HP:0001141)2.63400022
34True hermaphroditism (HP:0010459)2.59762409
35Increased hepatocellular lipid droplets (HP:0006565)2.57576131
36Stomatitis (HP:0010280)2.57016316
37Abnormality of magnesium homeostasis (HP:0004921)2.54619128
38Gaze-evoked nystagmus (HP:0000640)2.53639091
39Abolished electroretinogram (ERG) (HP:0000550)2.50870820
40Pachygyria (HP:0001302)2.50392444
41Inability to walk (HP:0002540)2.48024366
42Dry hair (HP:0011359)2.47295340
43Large for gestational age (HP:0001520)2.46113672
44Myokymia (HP:0002411)2.45796294
45Type 2 muscle fiber atrophy (HP:0003554)2.45706784
46Abnormality of the renal cortex (HP:0011035)2.41863315
47Elevated erythrocyte sedimentation rate (HP:0003565)2.36911289
48Progressive cerebellar ataxia (HP:0002073)2.36565193
49Tubular atrophy (HP:0000092)2.36387966
50Gait imbalance (HP:0002141)2.35657024
51Mediastinal lymphadenopathy (HP:0100721)2.34882414
523-Methylglutaconic aciduria (HP:0003535)2.34239716
53Recurrent abscess formation (HP:0002722)2.33981431
54Abnormal rod and cone electroretinograms (HP:0008323)2.33165872
55Meningitis (HP:0001287)2.31574588
56Cystic liver disease (HP:0006706)2.31283343
57Chronic hepatic failure (HP:0100626)2.29031000
58Exertional dyspnea (HP:0002875)2.27519938
59Abnormality of the prostate (HP:0008775)2.25665290
60Aplastic anemia (HP:0001915)2.24518629
61Cortical visual impairment (HP:0100704)2.24434312
62Atonic seizures (HP:0010819)2.24230270
63Ocular albinism (HP:0001107)2.24020618
64Polyphagia (HP:0002591)2.23282403
65Severe muscular hypotonia (HP:0006829)2.22417851
66Absent speech (HP:0001344)2.20543033
67Pendular nystagmus (HP:0012043)2.20137071
68Dialeptic seizures (HP:0011146)2.19765165
69Iris hypopigmentation (HP:0007730)2.19231742
70Retrobulbar optic neuritis (HP:0100654)2.18908530
71Optic neuritis (HP:0100653)2.18908530
72Chromosomal breakage induced by crosslinking agents (HP:0003221)2.17445765
73Progressive macrocephaly (HP:0004481)2.15720789
74Attenuation of retinal blood vessels (HP:0007843)2.15254700
75Polyuria (HP:0000103)2.15220672
76Aplasia/Hypoplasia of the fovea (HP:0008060)2.14707298
77Hypoplasia of the fovea (HP:0007750)2.14707298
78Myositis (HP:0100614)2.14686435
79Abnormality of secondary sexual hair (HP:0009888)2.14462220
80Abnormality of the axillary hair (HP:0100134)2.14462220
81Aplasia/Hypoplasia of the spleen (HP:0010451)2.13756658
82Muscle fiber atrophy (HP:0100295)2.11340149
83Hepatocellular necrosis (HP:0001404)2.08748897
84Decreased circulating renin level (HP:0003351)2.08428375
85Genetic anticipation (HP:0003743)2.07646102
86Stomach cancer (HP:0012126)2.07549459
87Abnormality of the labia minora (HP:0012880)2.07334111
88Increased corneal curvature (HP:0100692)2.06740858
89Keratoconus (HP:0000563)2.06740858
90Abnormal number of erythroid precursors (HP:0012131)2.06593825
91Abnormal respiratory epithelium morphology (HP:0012253)2.05360078
92Abnormal respiratory motile cilium morphology (HP:0005938)2.05360078
93Asplenia (HP:0001746)2.04454878
94Absent/shortened dynein arms (HP:0200106)2.04337797
95Dynein arm defect of respiratory motile cilia (HP:0012255)2.04337797
96Split foot (HP:0001839)2.03830704
97Optic nerve hypoplasia (HP:0000609)2.03717829
98Thoracic kyphosis (HP:0002942)2.03115482
99Abnormality of the pons (HP:0007361)2.02238250
100Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.99834593
101Epileptic encephalopathy (HP:0200134)1.99104351
102Decreased electroretinogram (ERG) amplitude (HP:0000654)1.98632943
103Hypoplasia of the pons (HP:0012110)1.98172281
104Oligodactyly (hands) (HP:0001180)1.98065989
105Acute necrotizing encephalopathy (HP:0006965)1.97626908
106Intestinal atresia (HP:0011100)1.96047827
107Decreased central vision (HP:0007663)1.95977999
108Abnormal sex determination (HP:0012244)1.95917646
109Sex reversal (HP:0012245)1.95917646
110Hypsarrhythmia (HP:0002521)1.95180765
111Concave nail (HP:0001598)1.93973024
112Congenital primary aphakia (HP:0007707)1.93662217
113Recurrent cutaneous fungal infections (HP:0011370)1.93655289
114Chronic mucocutaneous candidiasis (HP:0002728)1.93655289
115Sclerocornea (HP:0000647)1.93228353
116Supernumerary spleens (HP:0009799)1.92030750
117Pancreatic fibrosis (HP:0100732)1.91994972
118Epileptiform EEG discharges (HP:0011182)1.90586150
119EEG with generalized epileptiform discharges (HP:0011198)1.90431887
120Generalized tonic-clonic seizures (HP:0002069)1.89833477
121Lipid accumulation in hepatocytes (HP:0006561)1.89750983
122Increased IgM level (HP:0003496)1.88724060
123Clubbing of toes (HP:0100760)1.87904980
124Abnormality of renal resorption (HP:0011038)1.87624013
125Congenital sensorineural hearing impairment (HP:0008527)1.87303246
126Generalized hypopigmentation of hair (HP:0011358)1.87059422
127Bony spicule pigmentary retinopathy (HP:0007737)1.86553343
128Absence seizures (HP:0002121)1.86504958
129Optic disc pallor (HP:0000543)1.86094427
130Genital tract atresia (HP:0001827)1.85721871
131Spinal canal stenosis (HP:0003416)1.82771448
132Nephrogenic diabetes insipidus (HP:0009806)1.81670969
133Abnormality of cells of the erythroid lineage (HP:0012130)1.81665187
134Mitochondrial inheritance (HP:0001427)1.81513828
135Recurrent bacterial skin infections (HP:0005406)1.81150660
136Furrowed tongue (HP:0000221)1.80557920
137Anencephaly (HP:0002323)1.79710479
138Progressive inability to walk (HP:0002505)1.79460815
139Patchy hypopigmentation of hair (HP:0011365)1.78949014
140Eczematoid dermatitis (HP:0000976)1.78925692
141Vaginal atresia (HP:0000148)1.78472236
142Aplasia/Hypoplasia of the tibia (HP:0005772)1.78317966
143Horizontal nystagmus (HP:0000666)1.77862608
144Ketoacidosis (HP:0001993)1.77210943
145Abnormality of the fovea (HP:0000493)1.76336227
146Neoplasm of the adrenal cortex (HP:0100641)1.75779162
147Morphological abnormality of the pyramidal tract (HP:0002062)1.75422446
148Agitation (HP:0000713)1.73794126
149Hypomagnesemia (HP:0002917)1.73530081
150Abnormal urine output (HP:0012590)1.73345823
151Chromsome breakage (HP:0040012)1.73266888
152Abnormality of the preputium (HP:0100587)1.73255435
153Bile duct proliferation (HP:0001408)1.72148596
154Abnormal biliary tract physiology (HP:0012439)1.72148596
155Congenital hepatic fibrosis (HP:0002612)1.71684760
156Increased intramyocellular lipid droplets (HP:0012240)1.71276034
157Abnormal eating behavior (HP:0100738)1.71195077
158Pancreatic cysts (HP:0001737)1.71054080
159Status epilepticus (HP:0002133)1.70741513
160Methylmalonic acidemia (HP:0002912)1.70658683
161Pulmonary fibrosis (HP:0002206)1.70536566
162Abnormality of dental color (HP:0011073)1.70452135
163Drooling (HP:0002307)1.70227597
164Obstructive sleep apnea (HP:0002870)1.70204503
165Amelogenesis imperfecta (HP:0000705)1.69881300
166Broad-based gait (HP:0002136)1.68478787
167Bradycardia (HP:0001662)1.67122344
168Orchitis (HP:0100796)1.67119635
169Agammaglobulinemia (HP:0004432)1.66898210
170Limb dystonia (HP:0002451)1.64894656
171Hemoptysis (HP:0002105)1.64264667
172Annular pancreas (HP:0001734)1.64028549
173Abnormality of calcium-phosphate metabolism (HP:0100530)1.63300705
174Fair hair (HP:0002286)1.62655712
175Basal ganglia calcification (HP:0002135)1.62378451
176Sleep apnea (HP:0010535)1.61563785
177Median cleft lip (HP:0000161)1.61272280
178Aplasia/Hypoplasia of the uvula (HP:0010293)1.60719493

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TNIK5.95109003
2FRK4.81388292
3CASK3.69965242
4MUSK3.46589649
5EIF2AK33.30723031
6MAP2K73.00935907
7MKNK22.75619604
8STK162.65169395
9MAP4K22.59271498
10IRAK42.44629304
11MAP3K122.32081433
12WNK32.29618215
13NTRK32.19126176
14IRAK32.17931905
15FGFR22.13861768
16NLK2.10397269
17CAMKK22.01470178
18INSRR1.91986373
19PHKG11.90552981
20PHKG21.90552981
21PRPF4B1.87568157
22DYRK21.86200220
23FES1.85725790
24NME21.84877101
25WNK41.74633126
26TXK1.66219185
27RIPK41.61787062
28OXSR11.61535987
29MAPK131.56829927
30EIF2AK21.54936198
31NUAK11.53840518
32MKNK11.51961623
33CDK191.51642590
34PAK31.50125972
35TEC1.49594069
36BMPR21.47198062
37STK381.46389420
38CLK11.40752931
39SRPK11.35286386
40STK391.35267934
41SIK21.34163216
42TRIM281.34138928
43YES11.27774304
44IRAK21.27283693
45TLK11.26434289
46PRKD21.21910251
47ADRBK21.21116408
48MAP3K141.18123025
49MARK11.15802701
50CAMK11.15018104
51CSNK1G21.13853477
52PNCK1.09356741
53CAMKK11.04261372
54PLK21.03837219
55VRK11.00652739
56IRAK10.99420736
57PINK10.99340910
58TNK20.97537990
59PRKD30.95726514
60ZAK0.95156873
61STK110.92364508
62CDK30.91642175
63CSNK1G30.90691002
64MINK10.90197077
65KIT0.89846856
66NEK60.88143829
67ADRBK10.88007797
68GRK70.85904082
69IKBKE0.84573248
70BLK0.84134508
71SGK4940.83149092
72SGK2230.83149092
73UHMK10.83039969
74TAOK20.82019422
75PRKCI0.80485214
76BCR0.80480817
77TAOK30.78577058
78PAK60.77690341
79PRKCH0.77130413
80ACVR1B0.77084194
81PIM20.77024720
82EPHA40.76827451
83CSNK1A1L0.75006717
84BTK0.73722445
85SIK30.72895091
86IKBKB0.71283309
87SYK0.71197647
88PKN10.69893352
89BMPR1B0.66834813
90ITK0.64401072
91MAP2K60.64168576
92PTK2B0.63024336
93PRKG20.62815423
94EPHA30.62315849
95GRK50.61532016
96CSNK1A10.60826881
97LYN0.57147891
98DAPK10.54827563
99STK38L0.53470087
100ERBB30.52025207
101NTRK20.51747703
102HIPK20.51597778
103MAP3K90.50810949
104CAMK2B0.50456756
105CAMK2A0.50406464
106MAP3K10.48587132
107SGK20.47691765
108PRKCZ0.47528862
109ERBB20.47350945
110MAPKAPK50.45500669
111MAP3K40.44391407
112BCKDK0.43597827
113PRKCG0.42446070
114MAP3K130.42062979
115PRKCQ0.42029453
116SGK10.42025171
117PRKAA10.41369390
118CDK80.41138572
119CCNB10.40727065
120CDK50.39474225
121DAPK20.39139227
122CAMK40.38933571
123DYRK1A0.38267664
124PLK30.37314436
125FER0.36772434
126CSNK1D0.36284504
127MARK30.35949002
128ARAF0.34469258
129TIE10.33717343
130PRKCA0.33316011
131TYRO30.32850335
132PLK40.32285264
133MAPK150.31490385
134MATK0.31395566
135MAP3K110.31052996
136MAPK40.30384435
137PRKCE0.30197699
138TBK10.29676147
139PIK3CA0.29606455
140PRKCD0.28631115
141HCK0.26744762
142NME10.26385021
143GRK10.25619643
144CSNK1G10.24640966
145CAMK2D0.22726762
146LCK0.22497620
147PRKACA0.21051067
148MAP2K40.20624999
149MAP3K60.20594310
150BRAF0.20592361
151PRKG10.19711464

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.88891626
2Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.68048448
3Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.21897001
4Maturity onset diabetes of the young_Homo sapiens_hsa049502.14192195
5Butanoate metabolism_Homo sapiens_hsa006502.11788614
6alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.06370869
7Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.98666758
8Linoleic acid metabolism_Homo sapiens_hsa005911.96284153
9Ribosome_Homo sapiens_hsa030101.91417512
10Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.87401661
11Graft-versus-host disease_Homo sapiens_hsa053321.82561241
12Protein export_Homo sapiens_hsa030601.81475877
13Nitrogen metabolism_Homo sapiens_hsa009101.81373766
14Morphine addiction_Homo sapiens_hsa050321.77641757
15Synaptic vesicle cycle_Homo sapiens_hsa047211.73636804
16DNA replication_Homo sapiens_hsa030301.70622377
17Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.70505444
18SNARE interactions in vesicular transport_Homo sapiens_hsa041301.69142713
19Olfactory transduction_Homo sapiens_hsa047401.64294568
20Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.62285685
21Allograft rejection_Homo sapiens_hsa053301.60635342
22Homologous recombination_Homo sapiens_hsa034401.59105240
23Glutamatergic synapse_Homo sapiens_hsa047241.57361549
24Other glycan degradation_Homo sapiens_hsa005111.52910238
25Taste transduction_Homo sapiens_hsa047421.50903069
26Type I diabetes mellitus_Homo sapiens_hsa049401.49471533
27GABAergic synapse_Homo sapiens_hsa047271.48275984
28Circadian entrainment_Homo sapiens_hsa047131.47659335
29Fanconi anemia pathway_Homo sapiens_hsa034601.47511109
30Selenocompound metabolism_Homo sapiens_hsa004501.47416352
31Cardiac muscle contraction_Homo sapiens_hsa042601.44732331
32Phototransduction_Homo sapiens_hsa047441.41673528
33Serotonergic synapse_Homo sapiens_hsa047261.33295573
34N-Glycan biosynthesis_Homo sapiens_hsa005101.32513506
35RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.28356184
36Tryptophan metabolism_Homo sapiens_hsa003801.22432154
37Primary immunodeficiency_Homo sapiens_hsa053401.21299359
38Asthma_Homo sapiens_hsa053101.19954785
39Intestinal immune network for IgA production_Homo sapiens_hsa046721.17575344
40Oxidative phosphorylation_Homo sapiens_hsa001901.15807135
41Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.14629984
42Sphingolipid metabolism_Homo sapiens_hsa006001.14119242
43Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.13355924
44Cholinergic synapse_Homo sapiens_hsa047251.11666954
45Caffeine metabolism_Homo sapiens_hsa002321.10988672
46Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.09761392
47Propanoate metabolism_Homo sapiens_hsa006401.08255222
48Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.08117776
49Autoimmune thyroid disease_Homo sapiens_hsa053201.06634511
50RNA polymerase_Homo sapiens_hsa030201.03449304
51Rheumatoid arthritis_Homo sapiens_hsa053231.03349372
52Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.03071919
53Insulin secretion_Homo sapiens_hsa049111.02973457
54Calcium signaling pathway_Homo sapiens_hsa040201.02635160
55NF-kappa B signaling pathway_Homo sapiens_hsa040641.00708193
56Amphetamine addiction_Homo sapiens_hsa050310.99771571
57Leishmaniasis_Homo sapiens_hsa051400.98740908
58Salivary secretion_Homo sapiens_hsa049700.98574192
59Toll-like receptor signaling pathway_Homo sapiens_hsa046200.98250756
60Long-term depression_Homo sapiens_hsa047300.97220897
61Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.97020903
62Pyrimidine metabolism_Homo sapiens_hsa002400.95931628
63Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.95500195
64Purine metabolism_Homo sapiens_hsa002300.94597639
65Ovarian steroidogenesis_Homo sapiens_hsa049130.94449777
66ABC transporters_Homo sapiens_hsa020100.94058388
67Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.93887455
68Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.92436139
69Arachidonic acid metabolism_Homo sapiens_hsa005900.91512918
70Long-term potentiation_Homo sapiens_hsa047200.91353882
71Measles_Homo sapiens_hsa051620.90102940
72Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.89621789
73Collecting duct acid secretion_Homo sapiens_hsa049660.89511696
74Basal transcription factors_Homo sapiens_hsa030220.87803740
75Aldosterone synthesis and secretion_Homo sapiens_hsa049250.87773418
76Peroxisome_Homo sapiens_hsa041460.86284138
77Regulation of autophagy_Homo sapiens_hsa041400.85629586
78beta-Alanine metabolism_Homo sapiens_hsa004100.84415268
79Renin secretion_Homo sapiens_hsa049240.83613506
80Hematopoietic cell lineage_Homo sapiens_hsa046400.83085848
81Oxytocin signaling pathway_Homo sapiens_hsa049210.82633989
82Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.81130316
83Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.81025611
84Thyroid cancer_Homo sapiens_hsa052160.79653345
85Base excision repair_Homo sapiens_hsa034100.78716765
86Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.77169675
87Vitamin B6 metabolism_Homo sapiens_hsa007500.76672102
88Dopaminergic synapse_Homo sapiens_hsa047280.76548693
89African trypanosomiasis_Homo sapiens_hsa051430.75356357
90NOD-like receptor signaling pathway_Homo sapiens_hsa046210.75327296
91Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.75124865
92Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.74296340
93Pertussis_Homo sapiens_hsa051330.73752586
94Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.72563079
95Mismatch repair_Homo sapiens_hsa034300.70824985
96Primary bile acid biosynthesis_Homo sapiens_hsa001200.70622472
97Cocaine addiction_Homo sapiens_hsa050300.68867875
98Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.68832203
99Alzheimers disease_Homo sapiens_hsa050100.68750588
100Parkinsons disease_Homo sapiens_hsa050120.68592864
101Circadian rhythm_Homo sapiens_hsa047100.65617452
102Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.65286526
103Tuberculosis_Homo sapiens_hsa051520.63986316
104Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.63720987
105cAMP signaling pathway_Homo sapiens_hsa040240.63156338
106Thyroid hormone synthesis_Homo sapiens_hsa049180.62490713
107Huntingtons disease_Homo sapiens_hsa050160.62200294
108Vascular smooth muscle contraction_Homo sapiens_hsa042700.61562010
109Mineral absorption_Homo sapiens_hsa049780.60887135
110Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.60805454
111Jak-STAT signaling pathway_Homo sapiens_hsa046300.59619968
112Chemokine signaling pathway_Homo sapiens_hsa040620.59250224
113Nucleotide excision repair_Homo sapiens_hsa034200.58964607
114Malaria_Homo sapiens_hsa051440.58948619
115Axon guidance_Homo sapiens_hsa043600.57870867
116RNA degradation_Homo sapiens_hsa030180.57385954
117Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.57320179
118One carbon pool by folate_Homo sapiens_hsa006700.57212571
119Glycerolipid metabolism_Homo sapiens_hsa005610.56583460
120Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.56424052
121Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.56413563
122Hedgehog signaling pathway_Homo sapiens_hsa043400.55853821
123Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.54908910
124Herpes simplex infection_Homo sapiens_hsa051680.54357740
125Vibrio cholerae infection_Homo sapiens_hsa051100.54298565
126Gastric acid secretion_Homo sapiens_hsa049710.53954278
127Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.53520450
128Salmonella infection_Homo sapiens_hsa051320.53183123
129Ether lipid metabolism_Homo sapiens_hsa005650.52755935
130Bile secretion_Homo sapiens_hsa049760.50489544
131Osteoclast differentiation_Homo sapiens_hsa043800.50268305
132Non-homologous end-joining_Homo sapiens_hsa034500.49727573
133Transcriptional misregulation in cancer_Homo sapiens_hsa052020.48528521
134Retinol metabolism_Homo sapiens_hsa008300.47927245
135Dorso-ventral axis formation_Homo sapiens_hsa043200.47237554
136Proteasome_Homo sapiens_hsa030500.45861616
137Phagosome_Homo sapiens_hsa041450.45804272
138Influenza A_Homo sapiens_hsa051640.45151753
139Wnt signaling pathway_Homo sapiens_hsa043100.44598152
140Steroid biosynthesis_Homo sapiens_hsa001000.44482469
141Glycerophospholipid metabolism_Homo sapiens_hsa005640.41944909
142Carbohydrate digestion and absorption_Homo sapiens_hsa049730.41882471
143Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.41609046
144Metabolic pathways_Homo sapiens_hsa011000.41252482
145Steroid hormone biosynthesis_Homo sapiens_hsa001400.39978187
146Chemical carcinogenesis_Homo sapiens_hsa052040.39355889
147Pancreatic secretion_Homo sapiens_hsa049720.38649734
148Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.38030467
149Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.37181966

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