FRS3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a substrate for the fibroblast growth factor receptor. The encoded protein is found in the peripheral plasma membrane and links fibroblast growth factor receptor stimulation to activators of Ras. The encoded protein down-regulates extracellular regulated kinase 2 through direct binding. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of synapse maturation (GO:0090128)5.95558810
2regulation of short-term neuronal synaptic plasticity (GO:0048172)4.93340662
3synaptic vesicle maturation (GO:0016188)4.85258262
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.71253435
5neurotransmitter-gated ion channel clustering (GO:0072578)4.62953743
6neuron cell-cell adhesion (GO:0007158)4.36513640
7vocalization behavior (GO:0071625)4.32753614
8synaptic vesicle exocytosis (GO:0016079)4.26121912
9negative regulation of catenin import into nucleus (GO:0035414)4.23583690
10positive regulation of dendritic spine development (GO:0060999)4.15000736
11glutamate secretion (GO:0014047)4.10891568
12neuromuscular process controlling posture (GO:0050884)4.10848335
13regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.07571149
14positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.05739127
15protein localization to synapse (GO:0035418)4.05532728
16locomotory exploration behavior (GO:0035641)4.00186517
17positive regulation of dendritic spine morphogenesis (GO:0061003)3.93979517
18regulation of synaptic vesicle exocytosis (GO:2000300)3.90614171
19neurotransmitter secretion (GO:0007269)3.87482382
20neuronal action potential propagation (GO:0019227)3.85975751
21urinary tract smooth muscle contraction (GO:0014848)3.80942642
22ionotropic glutamate receptor signaling pathway (GO:0035235)3.73825812
23gamma-aminobutyric acid transport (GO:0015812)3.69626207
24cell migration in hindbrain (GO:0021535)3.69471918
25regulation of glutamate receptor signaling pathway (GO:1900449)3.65657232
26neuron recognition (GO:0008038)3.64898756
27proline transport (GO:0015824)3.61553021
28regulation of cilium movement (GO:0003352)3.60627035
29layer formation in cerebral cortex (GO:0021819)3.59841967
30behavioral response to nicotine (GO:0035095)3.56923611
31cellular potassium ion homeostasis (GO:0030007)3.53698101
32central nervous system projection neuron axonogenesis (GO:0021952)3.51239421
33neurotransmitter transport (GO:0006836)3.44445365
34regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.44014764
35exploration behavior (GO:0035640)3.43377215
36regulation of synaptic vesicle transport (GO:1902803)3.42050104
37regulation of voltage-gated calcium channel activity (GO:1901385)3.35996172
38retinal cone cell development (GO:0046549)3.35223272
39synaptic vesicle endocytosis (GO:0048488)3.34635370
40regulation of neuronal synaptic plasticity (GO:0048168)3.33732511
41synaptic transmission, glutamatergic (GO:0035249)3.33188471
42regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.32393609
43acrosome reaction (GO:0007340)3.31329468
44regulation of microtubule-based movement (GO:0060632)3.29344009
45dendritic spine morphogenesis (GO:0060997)3.29074414
46glutamate receptor signaling pathway (GO:0007215)3.27998589
47neuron-neuron synaptic transmission (GO:0007270)3.26248061
48negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.25150409
49calcium ion-dependent exocytosis (GO:0017156)3.24815781
50negative regulation of microtubule polymerization (GO:0031115)3.24697388
51axonal fasciculation (GO:0007413)3.24455988
52regulation of long-term neuronal synaptic plasticity (GO:0048169)3.23521888
53neuronal ion channel clustering (GO:0045161)3.22064851
54transmission of nerve impulse (GO:0019226)3.17831890
55regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.15407885
56regulation of dendritic spine development (GO:0060998)3.15231656
57cochlea development (GO:0090102)3.12994718
58pyrimidine nucleobase catabolic process (GO:0006208)3.11980925
59negative regulation of Ras GTPase activity (GO:0034261)3.08837531
60positive regulation of dendrite development (GO:1900006)3.08770180
61regulation of synapse structural plasticity (GO:0051823)3.08755038
62regulation of neurotransmitter levels (GO:0001505)3.08323596
63sperm motility (GO:0030317)3.07763242
64regulation of respiratory gaseous exchange (GO:0043576)3.07115643
65ventricular system development (GO:0021591)3.04667814
66cAMP catabolic process (GO:0006198)3.03248923
67membrane depolarization during action potential (GO:0086010)3.03051690
68positive regulation of synaptic transmission, GABAergic (GO:0032230)3.02298388
69microtubule nucleation (GO:0007020)3.02065070
70mating behavior (GO:0007617)3.01426260
71regulation of synapse organization (GO:0050807)3.01147425
72neuromuscular synaptic transmission (GO:0007274)3.00700307
73establishment of mitochondrion localization (GO:0051654)3.00252047
74cerebellar granule cell differentiation (GO:0021707)2.99448891
75positive regulation of synapse assembly (GO:0051965)2.99179283
76membrane hyperpolarization (GO:0060081)2.97819262
77phosphorelay signal transduction system (GO:0000160)2.97509606
78gamma-aminobutyric acid signaling pathway (GO:0007214)2.97409630
79central nervous system myelination (GO:0022010)2.97348118
80axon ensheathment in central nervous system (GO:0032291)2.97348118
81positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.97076032
82regulation of G0 to G1 transition (GO:0070316)2.93333332
83positive regulation of synapse maturation (GO:0090129)2.91396146
84neuromuscular process controlling balance (GO:0050885)2.88824409
85cilium movement (GO:0003341)2.87864083
86presynaptic membrane organization (GO:0097090)2.87266215
87negative regulation of synaptic transmission, GABAergic (GO:0032229)2.86999726
88mechanosensory behavior (GO:0007638)2.86428366
89G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.85934546
90primary amino compound metabolic process (GO:1901160)2.85840497
91presynaptic membrane assembly (GO:0097105)2.85475695
92cilium or flagellum-dependent cell motility (GO:0001539)2.85161988
93regulation of glutamate secretion (GO:0014048)2.84713863
94regulation of excitatory postsynaptic membrane potential (GO:0060079)2.84607087
95vesicle transport along microtubule (GO:0047496)2.84433539
96epithelial cilium movement (GO:0003351)2.83686496
97protein localization to cilium (GO:0061512)2.82276633
98axonemal dynein complex assembly (GO:0070286)2.82178203
99postsynaptic membrane organization (GO:0001941)2.81871234
100regulation of vesicle fusion (GO:0031338)2.80241166
101regulation of postsynaptic membrane potential (GO:0060078)2.80017334
102regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.79807862
103cyclic nucleotide catabolic process (GO:0009214)2.78241476
104microtubule severing (GO:0051013)2.78067591
105synapse assembly (GO:0007416)2.75936441
106organelle transport along microtubule (GO:0072384)2.75493125
107membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.74292229
108fear response (GO:0042596)2.73579593
109long-term memory (GO:0007616)2.72494680
110growth hormone secretion (GO:0030252)2.71783762
111membrane depolarization (GO:0051899)2.71672239
112mitochondrion transport along microtubule (GO:0047497)2.71156006
113establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.71156006
114positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.70758861
115activation of protein kinase A activity (GO:0034199)2.70562074
116cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.70385507
117auditory behavior (GO:0031223)2.69877458
118positive regulation of membrane potential (GO:0045838)2.69789142
119neuromuscular process (GO:0050905)2.69607983
120synapse organization (GO:0050808)2.69345330
121behavioral defense response (GO:0002209)2.67525374
122behavioral fear response (GO:0001662)2.67525374
123synaptic vesicle docking involved in exocytosis (GO:0016081)2.67267855
124dendrite morphogenesis (GO:0048813)2.67048343
125synaptic transmission (GO:0007268)2.66847872
126positive regulation of meiosis (GO:0045836)2.65831152
127cerebellar Purkinje cell differentiation (GO:0021702)2.65784265
128calcium-mediated signaling using intracellular calcium source (GO:0035584)2.65123448
129regulation of respiratory system process (GO:0044065)2.64463515
130dendritic spine organization (GO:0097061)2.64360283
131regulation of protein kinase A signaling (GO:0010738)2.63278411
132regulation of dendritic spine morphogenesis (GO:0061001)2.62582026
133regulation of synaptic plasticity (GO:0048167)2.62291641
134glycine transport (GO:0015816)2.61881822
135regulation of neurotransmitter secretion (GO:0046928)2.61803230

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.21513801
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.80752146
3REST_21632747_ChIP-Seq_MESCs_Mouse2.80423205
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.46325971
5NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.44781637
6THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.37127133
7ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.32561034
8JARID2_20064375_ChIP-Seq_MESCs_Mouse2.32535693
9SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.29860836
10GBX2_23144817_ChIP-Seq_PC3_Human2.28960064
11REST_18959480_ChIP-ChIP_MESCs_Mouse2.26819969
12EZH2_27304074_Chip-Seq_ESCs_Mouse2.25336762
13EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.25155479
14RARB_27405468_Chip-Seq_BRAIN_Mouse2.23651072
15JARID2_20075857_ChIP-Seq_MESCs_Mouse2.21298674
16* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.19658976
17EZH2_18974828_ChIP-Seq_MESCs_Mouse2.18445179
18RNF2_18974828_ChIP-Seq_MESCs_Mouse2.18445179
19SUZ12_27294783_Chip-Seq_ESCs_Mouse2.16929719
20CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.12428891
21EZH2_27294783_Chip-Seq_ESCs_Mouse2.10924078
22MTF2_20144788_ChIP-Seq_MESCs_Mouse2.09967088
23GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.05787487
24E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.97823613
25RNF2_27304074_Chip-Seq_ESCs_Mouse1.96424411
26SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.95526165
27DROSHA_22980978_ChIP-Seq_HELA_Human1.95288422
28SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.90312412
29SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.88165432
30ERG_21242973_ChIP-ChIP_JURKAT_Human1.80203183
31ZNF274_21170338_ChIP-Seq_K562_Hela1.78490587
32RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.74949936
33EED_16625203_ChIP-ChIP_MESCs_Mouse1.74636975
34CTBP2_25329375_ChIP-Seq_LNCAP_Human1.68183274
35SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.67286251
36VDR_22108803_ChIP-Seq_LS180_Human1.64613831
37MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.62518516
38STAT6_21828071_ChIP-Seq_BEAS2B_Human1.59347349
39CTBP1_25329375_ChIP-Seq_LNCAP_Human1.57630391
40SRY_22984422_ChIP-ChIP_TESTIS_Rat1.55158995
41IKZF1_21737484_ChIP-ChIP_HCT116_Human1.53200872
42BMI1_23680149_ChIP-Seq_NPCS_Mouse1.53046955
43RNF2_27304074_Chip-Seq_NSC_Mouse1.52093347
44LXR_22292898_ChIP-Seq_THP-1_Human1.50583203
45CBX2_27304074_Chip-Seq_ESCs_Mouse1.44750224
46RING1B_27294783_Chip-Seq_ESCs_Mouse1.43540123
47ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.39947480
48ZFP281_18757296_ChIP-ChIP_E14_Mouse1.37705227
49PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.36247368
50RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.34341576
51ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.31439341
52VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.30866706
53P68_20966046_ChIP-Seq_HELA_Human1.30507222
54RING1B_27294783_Chip-Seq_NPCs_Mouse1.30455603
55KDM2B_26808549_Chip-Seq_SUP-B15_Human1.28567221
56CTCF_27219007_Chip-Seq_Bcells_Human1.25765260
57KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.21683879
58KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.21683879
59KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.21683879
60TAF15_26573619_Chip-Seq_HEK293_Human1.21401563
61NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.20799580
62GATA1_26923725_Chip-Seq_HPCs_Mouse1.19256080
63SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.16670704
64MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.15609401
65* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.12693151
66SMAD4_21799915_ChIP-Seq_A2780_Human1.10774636
67PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.08636231
68DNAJC2_21179169_ChIP-ChIP_NT2_Human1.08136405
69TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.07702629
70TET1_21490601_ChIP-Seq_MESCs_Mouse1.05906379
71CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.05877166
72* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.05051040
73STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.04800012
74PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.04607509
75TP53_20018659_ChIP-ChIP_R1E_Mouse1.01381583
76KDM2B_26808549_Chip-Seq_K562_Human1.00841221
77SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.00162025
78KLF4_19829295_ChIP-Seq_ESCs_Human0.99890509
79ZFP281_27345836_Chip-Seq_ESCs_Mouse0.99731923
80SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.99630647
81* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.99409607
82TET1_21451524_ChIP-Seq_MESCs_Mouse0.97662858
83SMC4_20622854_ChIP-Seq_HELA_Human0.96846425
84SOX2_21211035_ChIP-Seq_LN229_Gbm0.96834444
85KDM2B_26808549_Chip-Seq_DND41_Human0.96579473
86RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.96028229
87WT1_25993318_ChIP-Seq_PODOCYTE_Human0.95578128
88CREB1_26743006_Chip-Seq_LNCaP_Human0.95536597
89AR_19668381_ChIP-Seq_PC3_Human0.94931325
90SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.94257554
91OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.92630121
92SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.91954141
93TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91336122
94ZFP57_27257070_Chip-Seq_ESCs_Mouse0.90991428
95SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.90599492
96ELK4_26923725_Chip-Seq_MESODERM_Mouse0.90220782
97P53_22127205_ChIP-Seq_FIBROBLAST_Human0.90143706
98GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.89300925
99* POU5F1_16518401_ChIP-PET_MESCs_Mouse0.89185757
100AR_21572438_ChIP-Seq_LNCaP_Human0.88368588
101SMAD3_21741376_ChIP-Seq_EPCs_Human0.88049198
102GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87918824
103PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.87551897
104TOP2B_26459242_ChIP-Seq_MCF-7_Human0.87131341
105SA1_27219007_Chip-Seq_Bcells_Human0.86785610
106SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.86712091
107BCL6_27268052_Chip-Seq_Bcells_Human0.86055867
108SMAD3_21741376_ChIP-Seq_ESCs_Human0.85713963
109TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.85074482
110STAT3_23295773_ChIP-Seq_U87_Human0.85002384
111MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.84353168
112* STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.83936797
113PHF8_20622854_ChIP-Seq_HELA_Human0.83509482
114CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.83337845
115* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.83086918
116KDM2B_26808549_Chip-Seq_JURKAT_Human0.82519319
117AHR_22903824_ChIP-Seq_MCF-7_Human0.82491312
118ARNT_22903824_ChIP-Seq_MCF-7_Human0.82076890
119EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.82047624
120TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.82002671
121CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.81386040
122POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.80696625
123TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.80696625
124SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.80646721
125* TCF4_23295773_ChIP-Seq_U87_Human0.80578410
126OCT4_19829295_ChIP-Seq_ESCs_Human0.80526308
127E2F1_20622854_ChIP-Seq_HELA_Human0.79719290
128* PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.79112917
129BCOR_27268052_Chip-Seq_Bcells_Human0.78334949
130EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.78174004
131CTCF_20526341_ChIP-Seq_ESCs_Human0.76644036
132SMAD4_21741376_ChIP-Seq_ESCs_Human0.76283275
133DPY_21335234_ChIP-Seq_ESCs_Mouse0.75150979
134TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.73692833

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.62470413
2MP0003880_abnormal_central_pattern4.26542054
3MP0003635_abnormal_synaptic_transmissio3.34020763
4MP0004270_analgesia3.02408862
5MP0005410_abnormal_fertilization2.91463950
6MP0000569_abnormal_digit_pigmentation2.84244249
7MP0005423_abnormal_somatic_nervous2.83094880
8MP0009046_muscle_twitch2.80270515
9MP0002064_seizures2.76693846
10MP0009745_abnormal_behavioral_response2.75876916
11MP0002063_abnormal_learning/memory/cond2.72565730
12MP0001968_abnormal_touch/_nociception2.54730430
13MP0002572_abnormal_emotion/affect_behav2.50864040
14MP0002272_abnormal_nervous_system2.36213223
15MP0001486_abnormal_startle_reflex2.33794086
16MP0002734_abnormal_mechanical_nocicepti2.21758701
17MP0001440_abnormal_grooming_behavior2.16083056
18MP0006276_abnormal_autonomic_nervous2.11120725
19MP0003122_maternal_imprinting2.00202727
20MP0002733_abnormal_thermal_nociception2.00026433
21MP0000778_abnormal_nervous_system1.97280077
22MP0002653_abnormal_ependyma_morphology1.88704571
23MP0002736_abnormal_nociception_after1.86776375
24MP0002184_abnormal_innervation1.86214588
25MP0002822_catalepsy1.84009195
26MP0004858_abnormal_nervous_system1.82277842
27MP0002735_abnormal_chemical_nociception1.81750664
28MP0000566_synostosis1.81576467
29MP0002067_abnormal_sensory_capabilities1.80837516
30MP0001970_abnormal_pain_threshold1.78901581
31MP0000955_abnormal_spinal_cord1.75935253
32MP0003787_abnormal_imprinting1.72564333
33MP0005645_abnormal_hypothalamus_physiol1.70845695
34MP0001501_abnormal_sleep_pattern1.65703719
35MP0004142_abnormal_muscle_tone1.64324569
36MP0003329_amyloid_beta_deposits1.62115507
37MP0004133_heterotaxia1.57193530
38MP0002557_abnormal_social/conspecific_i1.54670186
39MP0004811_abnormal_neuron_physiology1.51904732
40MP0008877_abnormal_DNA_methylation1.51154807
41MP0001529_abnormal_vocalization1.46953025
42MP0004924_abnormal_behavior1.46045796
43MP0005386_behavior/neurological_phenoty1.46045796
44MP0002882_abnormal_neuron_morphology1.45890181
45MP0005623_abnormal_meninges_morphology1.45148272
46MP0004130_abnormal_muscle_cell1.44574775
47MP0002066_abnormal_motor_capabilities/c1.35679113
48MP0001984_abnormal_olfaction1.35585349
49MP0003698_abnormal_male_reproductive1.35176148
50MP0006072_abnormal_retinal_apoptosis1.35138082
51MP0005499_abnormal_olfactory_system1.35008075
52MP0005394_taste/olfaction_phenotype1.35008075
53MP0001188_hyperpigmentation1.34831951
54MP0004885_abnormal_endolymph1.34829106
55MP0008569_lethality_at_weaning1.30220412
56MP0003183_abnormal_peptide_metabolism1.29874716
57MP0003283_abnormal_digestive_organ1.25045458
58MP0001905_abnormal_dopamine_level1.22277057
59MP0002152_abnormal_brain_morphology1.21887485
60MP0000751_myopathy1.19938316
61MP0003121_genomic_imprinting1.14803516
62MP0003634_abnormal_glial_cell1.13829938
63MP0002229_neurodegeneration1.12294957
64MP0001502_abnormal_circadian_rhythm1.11856655
65MP0004742_abnormal_vestibular_system1.11643093
66MP0002752_abnormal_somatic_nervous1.10785179
67MP0005551_abnormal_eye_electrophysiolog1.08926739
68MP0004233_abnormal_muscle_weight1.06728286
69MP0001299_abnormal_eye_distance/1.01761251
70MP0003879_abnormal_hair_cell1.00206177
71MP0002909_abnormal_adrenal_gland0.98404371
72MP0003633_abnormal_nervous_system0.97103281
73MP0000534_abnormal_ureter_morphology0.95417000
74MP0004145_abnormal_muscle_electrophysio0.94897451
75MP0003137_abnormal_impulse_conducting0.94272718
76MP0003861_abnormal_nervous_system0.93506338
77MP0001986_abnormal_taste_sensitivity0.93029620
78MP0005670_abnormal_white_adipose0.91669010
79MP0006292_abnormal_olfactory_placode0.91640107
80MP0001963_abnormal_hearing_physiology0.90937587
81MP0003172_abnormal_lysosome_physiology0.89116955
82MP0003119_abnormal_digestive_system0.88236035
83MP0004147_increased_porphyrin_level0.87561888
84MP0003123_paternal_imprinting0.87268838
85MP0009840_abnormal_foam_cell0.87177846
86MP0003631_nervous_system_phenotype0.86706932
87MP0000920_abnormal_myelination0.86064568
88MP0002234_abnormal_pharynx_morphology0.85671188
89MP0008872_abnormal_physiological_respon0.85261094
90MP0000631_abnormal_neuroendocrine_gland0.85217842
91MP0001485_abnormal_pinna_reflex0.85080323
92MP0002069_abnormal_eating/drinking_beha0.84622229
93MP0000015_abnormal_ear_pigmentation0.84428439
94MP0001929_abnormal_gametogenesis0.83855438
95MP0002751_abnormal_autonomic_nervous0.83139512
96MP0002102_abnormal_ear_morphology0.81297731
97MP0001348_abnormal_lacrimal_gland0.80789766
98MP0005646_abnormal_pituitary_gland0.80299699
99MP0005253_abnormal_eye_physiology0.79694588
100MP0009780_abnormal_chondrocyte_physiolo0.78232920
101MP0005535_abnormal_body_temperature0.77511363
102MP0008961_abnormal_basal_metabolism0.77272629
103MP0004085_abnormal_heartbeat0.76482282
104MP0000604_amyloidosis0.76096735
105MP0002161_abnormal_fertility/fecundity0.74300078
106MP0003136_yellow_coat_color0.73601746
107MP0000049_abnormal_middle_ear0.70456793
108MP0003632_abnormal_nervous_system0.69961958
109MP0002332_abnormal_exercise_endurance0.69700750
110MP0004043_abnormal_pH_regulation0.66616804
111MP0000013_abnormal_adipose_tissue0.66555263
112MP0000026_abnormal_inner_ear0.65164064
113MP0003890_abnormal_embryonic-extraembry0.64712559
114MP0008874_decreased_physiological_sensi0.64562698
115MP0001943_abnormal_respiration0.64038726
116MP0008789_abnormal_olfactory_epithelium0.63085580
117MP0001664_abnormal_digestion0.62911926
118MP0002837_dystrophic_cardiac_calcinosis0.60715279
119MP0002638_abnormal_pupillary_reflex0.59920768
120MP0005195_abnormal_posterior_eye0.58564205
121MP0000003_abnormal_adipose_tissue0.56959482
122MP0003942_abnormal_urinary_system0.56778311

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)5.36529287
2Focal motor seizures (HP:0011153)5.12579660
3Absent/shortened dynein arms (HP:0200106)4.43626754
4Dynein arm defect of respiratory motile cilia (HP:0012255)4.43626754
5Febrile seizures (HP:0002373)4.20502109
6Focal seizures (HP:0007359)4.10444366
7Respiratory insufficiency due to defective ciliary clearance (HP:0200073)4.08243092
8Visual hallucinations (HP:0002367)3.93335815
9Epileptic encephalopathy (HP:0200134)3.89835439
10Atonic seizures (HP:0010819)3.75080376
11Abnormality of the lower motor neuron (HP:0002366)3.52200299
12Abnormal respiratory epithelium morphology (HP:0012253)3.49191200
13Abnormal respiratory motile cilium morphology (HP:0005938)3.49191200
14Abnormal respiratory motile cilium physiology (HP:0012261)3.43668237
15Diplopia (HP:0000651)3.41446982
16Abnormality of binocular vision (HP:0011514)3.41446982
17Abnormal ciliary motility (HP:0012262)3.36652979
18Supranuclear gaze palsy (HP:0000605)3.35805251
19Absence seizures (HP:0002121)3.19420550
20Poor speech (HP:0002465)3.05760616
21Progressive cerebellar ataxia (HP:0002073)3.04730503
22Dialeptic seizures (HP:0011146)3.00457402
23Ankle clonus (HP:0011448)2.97896086
24Abnormality of homocysteine metabolism (HP:0010919)2.96052112
25Homocystinuria (HP:0002156)2.96052112
26Generalized tonic-clonic seizures (HP:0002069)2.95595400
27Amblyopia (HP:0000646)2.71978128
28Hemiparesis (HP:0001269)2.70725299
29Hyperlipoproteinemia (HP:0010980)2.67502695
30Abnormality of the corticospinal tract (HP:0002492)2.66346723
31Neurofibrillary tangles (HP:0002185)2.65625147
32Hyperventilation (HP:0002883)2.61681169
33Akinesia (HP:0002304)2.60205628
34Cerebral hypomyelination (HP:0006808)2.58164231
35Cerebral inclusion bodies (HP:0100314)2.52475666
36Polyphagia (HP:0002591)2.51974955
37Hypoalphalipoproteinemia (HP:0003233)2.51882638
38Sleep apnea (HP:0010535)2.49545259
39Amyotrophic lateral sclerosis (HP:0007354)2.46880874
40Limb dystonia (HP:0002451)2.46795037
41Obstructive sleep apnea (HP:0002870)2.44642097
42Spastic gait (HP:0002064)2.43990269
43Rhinitis (HP:0012384)2.43245033
44Pheochromocytoma (HP:0002666)2.42521563
45Stereotypic behavior (HP:0000733)2.42475306
46Failure to thrive in infancy (HP:0001531)2.41510638
47Abnormality of the labia minora (HP:0012880)2.41309167
48Impaired vibration sensation in the lower limbs (HP:0002166)2.40080926
49Abnormal eating behavior (HP:0100738)2.35751408
50Prolonged QT interval (HP:0001657)2.35683945
51Tented upper lip vermilion (HP:0010804)2.35148201
52Infertility (HP:0000789)2.31588007
53Agitation (HP:0000713)2.29564012
54Gait imbalance (HP:0002141)2.28080935
55Annular pancreas (HP:0001734)2.23063997
56Postural instability (HP:0002172)2.22947582
57Dysmetria (HP:0001310)2.21914246
58Nonprogressive disorder (HP:0003680)2.16664055
59Dysdiadochokinesis (HP:0002075)2.15439271
60Specific learning disability (HP:0001328)2.14891504
61Broad-based gait (HP:0002136)2.14839835
62Protruding tongue (HP:0010808)2.14006092
63Neuroendocrine neoplasm (HP:0100634)2.13498715
64Apathy (HP:0000741)2.12741198
65Constricted visual fields (HP:0001133)2.12615710
66Rigidity (HP:0002063)2.11390229
67Lower limb muscle weakness (HP:0007340)2.10603216
68Intellectual disability, severe (HP:0010864)2.09454942
69Termporal pattern (HP:0011008)2.08061805
70Insidious onset (HP:0003587)2.08061805
71Visceral angiomatosis (HP:0100761)2.07705265
72Urinary bladder sphincter dysfunction (HP:0002839)2.05668432
73Congenital sensorineural hearing impairment (HP:0008527)2.04860409
74Diminished motivation (HP:0000745)2.04212662
75Action tremor (HP:0002345)2.04205955
76Degeneration of the lateral corticospinal tracts (HP:0002314)2.01988612
77Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.01988612
78Status epilepticus (HP:0002133)2.01521617
79Urinary urgency (HP:0000012)2.00791289
80Abnormal EKG (HP:0003115)2.00490437
81Generalized hypotonia (HP:0001290)1.99280332
82Hemangiomatosis (HP:0007461)1.98580193
83Excessive salivation (HP:0003781)1.98344799
84Drooling (HP:0002307)1.98344799
85Retinal dysplasia (HP:0007973)1.98049381
86Unsteady gait (HP:0002317)1.97511750
87Aplasia/Hypoplasia of the brainstem (HP:0007362)1.97106104
88Hypoplasia of the brainstem (HP:0002365)1.97106104
89Neoplasm of the heart (HP:0100544)1.96173417
90Morphological abnormality of the pyramidal tract (HP:0002062)1.91578519
91Clonus (HP:0002169)1.91443710
92Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.91338381
93Spinal canal stenosis (HP:0003416)1.91164912
94Depression (HP:0000716)1.91086134
95Intention tremor (HP:0002080)1.90943234
96Medial flaring of the eyebrow (HP:0010747)1.90702571
97Bulbous nose (HP:0000414)1.87704338
98Peripheral hypomyelination (HP:0007182)1.87682545
99Absent speech (HP:0001344)1.87070488
100Mutism (HP:0002300)1.86938590
101Congenital primary aphakia (HP:0007707)1.86445902
102Gaze-evoked nystagmus (HP:0000640)1.86441749
103Anxiety (HP:0000739)1.85904351
104Myotonia (HP:0002486)1.85837162
105Turricephaly (HP:0000262)1.84088027
106Abnormality of alanine metabolism (HP:0010916)1.83855534
107Hyperalaninemia (HP:0003348)1.83855534
108Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.83855534
109Birth length less than 3rd percentile (HP:0003561)1.83514221
110Lissencephaly (HP:0001339)1.83425726
111Torticollis (HP:0000473)1.83302905
112Anterior segment dysgenesis (HP:0007700)1.82817034
113J-shaped sella turcica (HP:0002680)1.81975513
114Progressive inability to walk (HP:0002505)1.81306958
115Esotropia (HP:0000565)1.80905202
116Type II lissencephaly (HP:0007260)1.80501683
117Truncal ataxia (HP:0002078)1.80312081
118Muscle hypertrophy of the lower extremities (HP:0008968)1.80230541
119Delayed CNS myelination (HP:0002188)1.80160230
120Neuronal loss in central nervous system (HP:0002529)1.78615343
121Generalized myoclonic seizures (HP:0002123)1.78465573
122Poor eye contact (HP:0000817)1.77684211
123Bradykinesia (HP:0002067)1.76902051
124Nephronophthisis (HP:0000090)1.76422665
125Oligomenorrhea (HP:0000876)1.76136811
126Bell-shaped thorax (HP:0001591)1.75994842
127Delusions (HP:0000746)1.75835700
128Vaginal atresia (HP:0000148)1.75597083
129Genital tract atresia (HP:0001827)1.74481745
130Impaired social interactions (HP:0000735)1.73589301
131Abnormal social behavior (HP:0012433)1.73589301
132Focal dystonia (HP:0004373)1.73578411
133Sensory axonal neuropathy (HP:0003390)1.72135702
134Anosmia (HP:0000458)1.72127950
135Inability to walk (HP:0002540)1.71745216
136Spastic tetraparesis (HP:0001285)1.71345839
137Resting tremor (HP:0002322)1.70977263
138EEG with generalized epileptiform discharges (HP:0011198)1.70120671
139Epileptiform EEG discharges (HP:0011182)1.70104297
140Clumsiness (HP:0002312)1.69675469
141Rapidly progressive (HP:0003678)1.69382224
142Spastic tetraplegia (HP:0002510)1.69271709
143Athetosis (HP:0002305)1.68773305
144Craniofacial dystonia (HP:0012179)1.68431751
145Hypsarrhythmia (HP:0002521)1.65073631

Predicted kinase interactions (KEA)

RankGene SetZ-score
1RIPK15.27943928
2MAP3K93.33635424
3NTRK33.30737272
4MARK12.98718219
5ACVR1B2.90109664
6PNCK2.81727263
7ICK2.70540164
8EPHA42.67290244
9PRKD32.58315173
10GRK52.37012421
11MAP3K42.36371377
12TYRO32.28555455
13MINK12.05590705
14UHMK12.00228271
15PAK61.86231399
16* NTRK21.81071015
17PDK41.75613427
18PDK31.75613427
19SIK21.74687931
20TNIK1.72614152
21CASK1.72109298
22LATS21.63610233
23NTRK11.62225039
24PHKG11.53910277
25PHKG21.53910277
26STK391.46584839
27MAP2K41.44363623
28STK381.40265188
29MAP2K71.37794664
30DAPK21.34993700
31WNK41.33698670
32PINK11.32262401
33AKT31.27914135
34TLK11.24076768
35CDK51.23273494
36MAP3K111.22760409
37MAPK151.21564425
38MAP2K31.17740406
39MARK21.17594033
40KSR21.13338005
41DDR21.12700145
42CDK191.12004569
43OXSR11.11914293
44MAPK131.11039774
45CAMK1G1.10882328
46ARAF1.10563294
47MAPK121.09061176
48SGK21.07288377
49WNK11.05884535
50PRKCG1.04776965
51FGR0.96924152
52CAMK2A0.96296409
53TAOK10.95765174
54BMPR1B0.95155060
55CDK150.94622064
56CAMKK10.93840802
57LMTK20.91965089
58BMPR20.91943813
59CDK180.91647299
60CAMK2B0.91588524
61PDK20.89268601
62EPHB20.89252907
63CDK140.88835644
64PLK20.88056847
65SGK30.85998020
66CDK11A0.85807886
67STK110.84824769
68SGK2230.80248820
69SGK4940.80248820
70PAK30.79808294
71CAMKK20.76769244
72ERBB30.75592136
73DAPK10.75576825
74KSR10.74987222
75PTK2B0.74554738
76CAMK2G0.69795894
77PRKCH0.68205368
78WNK30.67926506
79MAP3K70.67527233
80DYRK20.66175874
81RPS6KA20.65060427
82PKN10.63420857
83TESK10.62524437
84PRPF4B0.61932977
85CDK90.60074168
86MAP2K10.58919121
87MAP3K30.58088718
88CSNK1G20.58001235
89CAMK2D0.57460749
90MAP3K120.57084683
91BRAF0.56622414
92MAP3K60.56314524
93GRK70.55216454
94TNK20.55181976
95PRKCZ0.55028591
96ALK0.54555582
97TGFBR10.53961661
98RIPK40.53660549
99CDC42BPA0.53161818
100ROCK20.50167898
101PRKD20.50128333
102ADRBK10.50020551
103MATK0.49187559
104CAMK10.48878075
105SGK10.48375034
106CAMK1D0.48366461
107CAMK40.48224873
108CCNB10.48177804
109MAPK100.47814106
110DYRK1A0.47276504
111MAP4K20.46198854
112IRAK20.45248333
113PRKAA10.44307816
114NME10.44003974
115RPS6KA30.43277579
116LIMK10.42381333
117MAP3K20.41980547
118YES10.41934026
119PDK10.41654704
120CSNK1E0.40912148
121MAPKAPK50.38780847
122SIK30.38193451
123ADRBK20.37864191
124PDPK10.36987572
125MAP2K60.36986656
126GRK60.36564672
127PRKCI0.36415988
128MAPK40.35830810
129MAPK80.34954148
130TRIB30.32949671
131PRKACA0.32665436
132FYN0.32396332
133SYK0.32241860
134DYRK1B0.31928929
135MELK0.29867946
136PRKG10.27777621
137RPS6KB10.27032753

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.71996082
2Synaptic vesicle cycle_Homo sapiens_hsa047213.19150611
3GABAergic synapse_Homo sapiens_hsa047272.80652149
4Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.48218613
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.37759382
6Glutamatergic synapse_Homo sapiens_hsa047242.30811718
7Olfactory transduction_Homo sapiens_hsa047402.21809157
8Long-term potentiation_Homo sapiens_hsa047202.20716791
9Circadian entrainment_Homo sapiens_hsa047132.20205489
10Morphine addiction_Homo sapiens_hsa050322.18396951
11Taste transduction_Homo sapiens_hsa047422.18282898
12Amphetamine addiction_Homo sapiens_hsa050312.12391710
13Dopaminergic synapse_Homo sapiens_hsa047281.91229425
14Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.88569557
15Cardiac muscle contraction_Homo sapiens_hsa042601.88438518
16Collecting duct acid secretion_Homo sapiens_hsa049661.86135763
17Salivary secretion_Homo sapiens_hsa049701.81828962
18Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.76834508
19Insulin secretion_Homo sapiens_hsa049111.73299264
20Serotonergic synapse_Homo sapiens_hsa047261.67007692
21Oxidative phosphorylation_Homo sapiens_hsa001901.59285690
22Long-term depression_Homo sapiens_hsa047301.58331270
23Renin secretion_Homo sapiens_hsa049241.58071759
24Gastric acid secretion_Homo sapiens_hsa049711.54560209
25Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.49708520
26Cocaine addiction_Homo sapiens_hsa050301.48337550
27Cholinergic synapse_Homo sapiens_hsa047251.44411637
28Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.40732614
29Parkinsons disease_Homo sapiens_hsa050121.36426165
30Gap junction_Homo sapiens_hsa045401.35075635
31Calcium signaling pathway_Homo sapiens_hsa040201.34683515
32Axon guidance_Homo sapiens_hsa043601.32850814
33Oxytocin signaling pathway_Homo sapiens_hsa049211.31134250
34Dorso-ventral axis formation_Homo sapiens_hsa043201.30874149
35Aldosterone synthesis and secretion_Homo sapiens_hsa049251.28026067
36Alzheimers disease_Homo sapiens_hsa050101.19871847
37Huntingtons disease_Homo sapiens_hsa050161.15689434
38Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.13196710
39GnRH signaling pathway_Homo sapiens_hsa049121.12489358
40Vibrio cholerae infection_Homo sapiens_hsa051101.11789630
41Sulfur relay system_Homo sapiens_hsa041221.06434655
42Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.04098008
43Estrogen signaling pathway_Homo sapiens_hsa049151.00641966
44Fatty acid biosynthesis_Homo sapiens_hsa000611.00632823
45cAMP signaling pathway_Homo sapiens_hsa040240.99355046
46Hedgehog signaling pathway_Homo sapiens_hsa043400.98757204
47Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.98592668
48Oocyte meiosis_Homo sapiens_hsa041140.96640993
49Melanogenesis_Homo sapiens_hsa049160.96169155
50Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.92451745
51Phototransduction_Homo sapiens_hsa047440.90000101
52ErbB signaling pathway_Homo sapiens_hsa040120.87570852
53Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.86670135
54Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.86228209
55Phosphatidylinositol signaling system_Homo sapiens_hsa040700.82803759
56Regulation of autophagy_Homo sapiens_hsa041400.81876387
57Vascular smooth muscle contraction_Homo sapiens_hsa042700.81295201
58ABC transporters_Homo sapiens_hsa020100.81275340
59Glucagon signaling pathway_Homo sapiens_hsa049220.79193127
60Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.76382777
61cGMP-PKG signaling pathway_Homo sapiens_hsa040220.76345102
62Vitamin B6 metabolism_Homo sapiens_hsa007500.73811952
63Circadian rhythm_Homo sapiens_hsa047100.73387283
64Sphingolipid signaling pathway_Homo sapiens_hsa040710.69419974
65Bile secretion_Homo sapiens_hsa049760.68186311
66Butanoate metabolism_Homo sapiens_hsa006500.68084256
67Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.67443761
68MAPK signaling pathway_Homo sapiens_hsa040100.65188587
69Neurotrophin signaling pathway_Homo sapiens_hsa047220.64439904
70alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.63298012
71Glioma_Homo sapiens_hsa052140.61991106
72Wnt signaling pathway_Homo sapiens_hsa043100.60987487
73Type II diabetes mellitus_Homo sapiens_hsa049300.60975755
74Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.60648737
75Pyruvate metabolism_Homo sapiens_hsa006200.60198271
76Choline metabolism in cancer_Homo sapiens_hsa052310.59701628
77Alcoholism_Homo sapiens_hsa050340.58746633
78Prion diseases_Homo sapiens_hsa050200.58328799
79Thyroid hormone synthesis_Homo sapiens_hsa049180.57612771
80Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.57587766
81Phospholipase D signaling pathway_Homo sapiens_hsa040720.57556404
82Glycerophospholipid metabolism_Homo sapiens_hsa005640.57127043
83AMPK signaling pathway_Homo sapiens_hsa041520.57011635
84mTOR signaling pathway_Homo sapiens_hsa041500.55614620
85Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.55408579
86Ether lipid metabolism_Homo sapiens_hsa005650.55373376
87Dilated cardiomyopathy_Homo sapiens_hsa054140.55286611
88SNARE interactions in vesicular transport_Homo sapiens_hsa041300.53944868
89Maturity onset diabetes of the young_Homo sapiens_hsa049500.53903482
90Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.52372768
91Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.51855859
92Pancreatic secretion_Homo sapiens_hsa049720.51515932
93Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.51181070
94Ras signaling pathway_Homo sapiens_hsa040140.50020733
95Linoleic acid metabolism_Homo sapiens_hsa005910.49555902
96Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.49215193
97Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.49212270
98Nitrogen metabolism_Homo sapiens_hsa009100.46887717
99Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.45540527
100Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.44832637
101Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.41132390
102Arginine biosynthesis_Homo sapiens_hsa002200.40983007
103Longevity regulating pathway - mammal_Homo sapiens_hsa042110.40508913
104Other glycan degradation_Homo sapiens_hsa005110.40202490
105Tight junction_Homo sapiens_hsa045300.39612508
106Fructose and mannose metabolism_Homo sapiens_hsa000510.38964504
107VEGF signaling pathway_Homo sapiens_hsa043700.38386731
108Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.38205600
109Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.38181537
110Inositol phosphate metabolism_Homo sapiens_hsa005620.37921924
111Rap1 signaling pathway_Homo sapiens_hsa040150.37349120
112Ovarian steroidogenesis_Homo sapiens_hsa049130.37306665
113Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.37292862
114Basal cell carcinoma_Homo sapiens_hsa052170.36858661
115Endocytosis_Homo sapiens_hsa041440.36741106
116Carbohydrate digestion and absorption_Homo sapiens_hsa049730.36658753
117Insulin signaling pathway_Homo sapiens_hsa049100.36535166
118Arginine and proline metabolism_Homo sapiens_hsa003300.36241869
119Thyroid hormone signaling pathway_Homo sapiens_hsa049190.32196953
120Chemokine signaling pathway_Homo sapiens_hsa040620.28148469
121Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.28002296

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »