FRY

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)4.73009923
2vocalization behavior (GO:0071625)4.66967002
3positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.66613060
4regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.43671839
5locomotory exploration behavior (GO:0035641)4.41599172
6ionotropic glutamate receptor signaling pathway (GO:0035235)4.34040883
7positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.18081720
8synaptic vesicle maturation (GO:0016188)4.12179760
9membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.11471299
10regulation of glutamate receptor signaling pathway (GO:1900449)4.10908631
11neuron cell-cell adhesion (GO:0007158)4.06629969
12synaptic vesicle exocytosis (GO:0016079)4.04891371
13protein localization to synapse (GO:0035418)4.04560601
14glutamate receptor signaling pathway (GO:0007215)4.04187587
15regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.99132170
16synaptic transmission, glutamatergic (GO:0035249)3.80535027
17regulation of synaptic vesicle exocytosis (GO:2000300)3.74809294
18neuronal action potential propagation (GO:0019227)3.73616915
19glutamate secretion (GO:0014047)3.71997670
20neurotransmitter-gated ion channel clustering (GO:0072578)3.64665589
21neuron-neuron synaptic transmission (GO:0007270)3.58762876
22regulation of synapse structural plasticity (GO:0051823)3.53049681
23exploration behavior (GO:0035640)3.52089357
24synaptic vesicle docking involved in exocytosis (GO:0016081)3.51323528
25G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.47883886
26cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.47863076
27cerebellar Purkinje cell differentiation (GO:0021702)3.45909012
28regulation of long-term neuronal synaptic plasticity (GO:0048169)3.45686915
29long-term memory (GO:0007616)3.44186703
30positive regulation of phosphoprotein phosphatase activity (GO:0032516)3.43814464
31regulation of synaptic vesicle transport (GO:1902803)3.43437733
32regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.41510717
33regulation of neuronal synaptic plasticity (GO:0048168)3.39967736
34regulation of excitatory postsynaptic membrane potential (GO:0060079)3.39612575
35regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.36417079
36regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.35415461
37presynaptic membrane assembly (GO:0097105)3.31732880
38positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.29790773
39regulation of postsynaptic membrane potential (GO:0060078)3.29227643
40cell communication by electrical coupling (GO:0010644)3.29206155
41membrane depolarization during action potential (GO:0086010)3.29180990
42neurotransmitter secretion (GO:0007269)3.25075852
43proline transport (GO:0015824)3.24839087
44gamma-aminobutyric acid transport (GO:0015812)3.23939882
45negative regulation of synaptic transmission, GABAergic (GO:0032229)3.21962832
46cellular potassium ion homeostasis (GO:0030007)3.21959798
47activation of protein kinase A activity (GO:0034199)3.18732582
48dendritic spine morphogenesis (GO:0060997)3.17724737
49postsynaptic membrane organization (GO:0001941)3.14659119
50cellular response to epinephrine stimulus (GO:0071872)3.13374990
51positive regulation of membrane potential (GO:0045838)3.09898253
52transmission of nerve impulse (GO:0019226)3.09183884
53membrane depolarization (GO:0051899)3.05592878
54regulation of synaptic transmission, glutamatergic (GO:0051966)3.04773931
55gamma-aminobutyric acid signaling pathway (GO:0007214)3.04065802
56layer formation in cerebral cortex (GO:0021819)3.03628810
57regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.02672810
58startle response (GO:0001964)3.02235475
59myofibril assembly (GO:0030239)3.01999186
60presynaptic membrane organization (GO:0097090)3.01607123
61regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.01163609
62detection of calcium ion (GO:0005513)3.01131846
63neuron recognition (GO:0008038)3.00823197
64positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.99963808
65nerve growth factor signaling pathway (GO:0038180)2.98070235
66response to epinephrine (GO:0071871)2.96787076
67regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.95857344
68synaptic vesicle endocytosis (GO:0048488)2.92977772
69regulation of dendritic spine morphogenesis (GO:0061001)2.90384145
70regulation of neurotransmitter secretion (GO:0046928)2.90083983
71auditory behavior (GO:0031223)2.88993691
72positive regulation of potassium ion transmembrane transport (GO:1901381)2.87352395
73membrane hyperpolarization (GO:0060081)2.86683697
74regulation of relaxation of muscle (GO:1901077)2.86630961
75positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.86141207
76regulation of synaptic plasticity (GO:0048167)2.85018813
77regulation of cAMP-dependent protein kinase activity (GO:2000479)2.84206538
78regulation of vesicle fusion (GO:0031338)2.83144524
79response to auditory stimulus (GO:0010996)2.82912395
80negative regulation of cell killing (GO:0031342)2.82833148
81negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.82833148
82microglial cell activation (GO:0001774)2.81642536
83dendrite morphogenesis (GO:0048813)2.81551690
84long-term synaptic potentiation (GO:0060291)2.79986716
85synapse assembly (GO:0007416)2.78979392
86axonal fasciculation (GO:0007413)2.77796597
87L-amino acid import (GO:0043092)2.76930458
88neurotransmitter transport (GO:0006836)2.76800556
89regulation of membrane repolarization (GO:0060306)2.75498012
90positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.75228388
91positive regulation of synaptic transmission, GABAergic (GO:0032230)2.74424533
92positive regulation of gamma-delta T cell activation (GO:0046645)2.74151020
93cardiac myofibril assembly (GO:0055003)2.73808523
94glycine transport (GO:0015816)2.73755148
95cell communication involved in cardiac conduction (GO:0086065)2.73469872
96regulation of cell communication by electrical coupling (GO:0010649)2.73384493
97striatum development (GO:0021756)2.72334807
98regulation of voltage-gated calcium channel activity (GO:1901385)2.70948400
99sarcoplasmic reticulum calcium ion transport (GO:0070296)2.70471307
100learning (GO:0007612)2.69895198
101negative regulation of cytosolic calcium ion concentration (GO:0051481)2.68653223
102innervation (GO:0060384)2.68457925
103regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.68361121
104sodium ion export (GO:0071436)2.68220725
105adult walking behavior (GO:0007628)2.67589336
106detection of molecule of bacterial origin (GO:0032490)2.67305617
107regulation of dendritic spine development (GO:0060998)2.67223959
108cellular extravasation (GO:0045123)2.67034758
109regulation of neurotransmitter transport (GO:0051588)2.66433810
110positive regulation of synapse maturation (GO:0090129)2.65410846
111positive regulation of neurotransmitter secretion (GO:0001956)2.64254263
112regulation of actin filament-based movement (GO:1903115)2.64037587
113regulation of ARF protein signal transduction (GO:0032012)2.62390712
114multicellular organismal signaling (GO:0035637)2.62292017
115cerebellar granule cell differentiation (GO:0021707)2.62190634
116negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.61926056
117cardiac muscle hypertrophy (GO:0003300)2.61315192
118response to histamine (GO:0034776)2.60370070
119neutrophil mediated immunity (GO:0002446)2.57507778
120relaxation of cardiac muscle (GO:0055119)2.57295464
121cardiac muscle contraction (GO:0060048)2.56870897
122regulation of B cell receptor signaling pathway (GO:0050855)2.56643530
123positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.54668705
124striated muscle hypertrophy (GO:0014897)2.54237994
125muscle filament sliding (GO:0030049)2.45997867
126actin-myosin filament sliding (GO:0033275)2.45997867
127regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.45340317
128macrophage activation involved in immune response (GO:0002281)2.44448825
129cellular response to catecholamine stimulus (GO:0071870)2.42032494
130cellular response to monoamine stimulus (GO:0071868)2.42032494
131positive regulation of Rap GTPase activity (GO:0032854)2.39604626
132regulation of calcium ion transmembrane transport (GO:1903169)2.37434983
133regulation of calcium ion transmembrane transporter activity (GO:1901019)2.37434983
134macrophage activation (GO:0042116)2.36811360
135regulation of striated muscle contraction (GO:0006942)2.35898993
136response to catecholamine (GO:0071869)2.34969519
137response to monoamine (GO:0071867)2.34969519
138interkinetic nuclear migration (GO:0022027)2.34347153
139modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.33062475
140modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.33062475
141positive regulation by organism of defense response of other organism involved in symbiotic interact2.33062475
142modulation by symbiont of host immune response (GO:0052553)2.33062475
143positive regulation by symbiont of host defense response (GO:0052509)2.33062475
144modulation by symbiont of host defense response (GO:0052031)2.33062475
145macroautophagy (GO:0016236)2.32721170
146regulation of beta-amyloid formation (GO:1902003)2.31317723
147antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.30477852
148muscle hypertrophy (GO:0014896)2.29683757
149positive regulation of cation channel activity (GO:2001259)2.27602153
150myeloid leukocyte mediated immunity (GO:0002444)2.27462864
151regulation of Rap GTPase activity (GO:0032317)2.26907783
152potassium ion import (GO:0010107)2.26473740
153nucleus localization (GO:0051647)2.26395232
154cellular response to ethanol (GO:0071361)2.24208802
155activated T cell proliferation (GO:0050798)2.23673871
156establishment of protein localization to Golgi (GO:0072600)2.23575104
157regulation of cardiac muscle cell contraction (GO:0086004)2.22889834
158regulation of gamma-delta T cell activation (GO:0046643)2.22513753
159regulation of cardiac muscle contraction (GO:0055117)2.22432935
160neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.21954169
161phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.21820960
162regulation of gamma-delta T cell differentiation (GO:0045586)2.20081368
163urinary tract smooth muscle contraction (GO:0014848)2.19919973
164striated muscle contraction (GO:0006941)2.17105925
165sarcomere organization (GO:0045214)2.16670771
166positive regulation of phosphatase activity (GO:0010922)2.16504607
167regulation of sarcomere organization (GO:0060297)2.15766194
168skeletal muscle adaptation (GO:0043501)2.15630444
169regulation of skeletal muscle contraction (GO:0014819)2.14600918
170response to inactivity (GO:0014854)2.14294163

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.30864773
2GBX2_23144817_ChIP-Seq_PC3_Human4.03919325
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.83689518
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.75943539
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.74317881
6RNF2_18974828_ChIP-Seq_MESCs_Mouse2.43824640
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.43824640
8SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.36907289
9SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.34276707
10EZH2_27304074_Chip-Seq_ESCs_Mouse2.31301491
11SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.28842129
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.27355340
13* DROSHA_22980978_ChIP-Seq_HELA_Human2.21869036
14MTF2_20144788_ChIP-Seq_MESCs_Mouse2.20753368
15EED_16625203_ChIP-ChIP_MESCs_Mouse2.17336467
16SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.14216388
17REST_21632747_ChIP-Seq_MESCs_Mouse2.11816120
18GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.97682562
19RNF2_27304074_Chip-Seq_ESCs_Mouse1.97014774
20STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.96786935
21EZH2_27294783_Chip-Seq_ESCs_Mouse1.92499928
22SUZ12_27294783_Chip-Seq_ESCs_Mouse1.89148939
23SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.86719794
24AR_21572438_ChIP-Seq_LNCaP_Human1.86068995
25SMAD_19615063_ChIP-ChIP_OVARY_Human1.85492055
26ZFP57_27257070_Chip-Seq_ESCs_Mouse1.84199207
27TAF15_26573619_Chip-Seq_HEK293_Human1.83293924
28* SMAD4_21799915_ChIP-Seq_A2780_Human1.80233006
29FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.77493247
30RARB_27405468_Chip-Seq_BRAIN_Mouse1.75756694
31ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.74267078
32CTBP1_25329375_ChIP-Seq_LNCAP_Human1.71045068
33CDX2_19796622_ChIP-Seq_MESCs_Mouse1.70574008
34* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.70307144
35CTBP2_25329375_ChIP-Seq_LNCAP_Human1.68514190
36RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.64893844
37GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.62239775
38IKZF1_21737484_ChIP-ChIP_HCT116_Human1.58450330
39BP1_19119308_ChIP-ChIP_Hs578T_Human1.55608582
40REST_18959480_ChIP-ChIP_MESCs_Mouse1.54798788
41* P300_19829295_ChIP-Seq_ESCs_Human1.53228349
42BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.52564162
43TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.49836903
44PIAS1_25552417_ChIP-Seq_VCAP_Human1.46915431
45STAT3_23295773_ChIP-Seq_U87_Human1.45275717
46* SMAD3_21741376_ChIP-Seq_EPCs_Human1.42141529
47RUNX_20019798_ChIP-Seq_JUKART_Human1.41617748
48IGF1R_20145208_ChIP-Seq_DFB_Human1.41086102
49CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.40635784
50POU3F2_20337985_ChIP-ChIP_501MEL_Human1.38892509
51GATA1_22025678_ChIP-Seq_K562_Human1.37835405
52* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.36748538
53AHR_22903824_ChIP-Seq_MCF-7_Human1.35739579
54* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.34641738
55CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.34591475
56PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.34551311
57RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.34338294
58* AR_25329375_ChIP-Seq_VCAP_Human1.34195407
59ARNT_22903824_ChIP-Seq_MCF-7_Human1.32481152
60CBX2_27304074_Chip-Seq_ESCs_Mouse1.30947685
61BMI1_23680149_ChIP-Seq_NPCS_Mouse1.30410758
62IRF8_22096565_ChIP-ChIP_GC-B_Human1.29883035
63NR3C1_23031785_ChIP-Seq_PC12_Mouse1.29516417
64OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.28488525
65* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.28064797
66* SOX2_21211035_ChIP-Seq_LN229_Gbm1.27948432
67BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.27567696
68AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.27094440
69TCF4_23295773_ChIP-Seq_U87_Human1.26646121
70PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.24118601
71SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.24114353
72VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.21589821
73VDR_24787735_ChIP-Seq_THP-1_Human1.20173682
74TP53_16413492_ChIP-PET_HCT116_Human1.19679715
75* AR_19668381_ChIP-Seq_PC3_Human1.16522472
76* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.16137470
77EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.15475990
78CTNNB1_20460455_ChIP-Seq_HCT116_Human1.13990928
79* NR3C1_21868756_ChIP-Seq_MCF10A_Human1.13972956
80SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.13480207
81TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.12891683
82Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.12486358
83NANOG_18555785_Chip-Seq_ESCs_Mouse1.12267772
84UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.12063611
85ZNF274_21170338_ChIP-Seq_K562_Hela1.11393227
86ER_23166858_ChIP-Seq_MCF-7_Human1.11153181
87* RUNX2_22187159_ChIP-Seq_PCA_Human1.11031873
88NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.09901718
89P53_22127205_ChIP-Seq_FIBROBLAST_Human1.09692773
90WT1_25993318_ChIP-Seq_PODOCYTE_Human1.09656851
91MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.09300211
92RING1B_27294783_Chip-Seq_ESCs_Mouse1.09290467
93EP300_21415370_ChIP-Seq_HL-1_Mouse1.09278090
94RNF2_27304074_Chip-Seq_NSC_Mouse1.08022608
95PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.07226552
96NRF2_20460467_ChIP-Seq_MEFs_Mouse1.06732362
97NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.06732362
98YAP1_20516196_ChIP-Seq_MESCs_Mouse1.06460288
99E2F1_18555785_Chip-Seq_ESCs_Mouse1.05046031
100MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.04984528
101* TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04829755
102* POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.04829755
103BCAT_22108803_ChIP-Seq_LS180_Human1.04823048
104* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.03734519
105PRDM14_20953172_ChIP-Seq_ESCs_Human1.03694224
106FUS_26573619_Chip-Seq_HEK293_Human1.03687046
107SUZ12_27294783_Chip-Seq_NPCs_Mouse1.03001628
108CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02279025
109* GATA2_21666600_ChIP-Seq_HMVEC_Human1.01883257
110ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.01327237
111FLI1_27457419_Chip-Seq_LIVER_Mouse1.00315560
112FLI1_21867929_ChIP-Seq_TH2_Mouse0.99337685
113ESR1_20079471_ChIP-ChIP_T-47D_Human0.98886110
114* TP53_18474530_ChIP-ChIP_U2OS_Human0.98854169
115* KDM2B_26808549_Chip-Seq_REH_Human0.98500905
116PCGF2_27294783_Chip-Seq_ESCs_Mouse0.98439671
117VDR_22108803_ChIP-Seq_LS180_Human0.98423694
118EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.97635344
119PCGF2_27294783_Chip-Seq_NPCs_Mouse0.97612764
120* SMAD3_21741376_ChIP-Seq_HESCs_Human0.97423882
121RXR_22108803_ChIP-Seq_LS180_Human0.97348287
122* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.97119885
123MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.96949830
124* SMAD4_21741376_ChIP-Seq_HESCs_Human0.96246866
125FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.95735560
126CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.94545452
127EZH2_27294783_Chip-Seq_NPCs_Mouse0.94233676
128SCL_19346495_ChIP-Seq_HPC-7_Human0.93243581

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.19823903
2MP0003880_abnormal_central_pattern4.04841600
3MP0003635_abnormal_synaptic_transmissio3.50427542
4MP0004270_analgesia3.29252476
5MP0009046_muscle_twitch3.01024891
6MP0009745_abnormal_behavioral_response3.00024792
7MP0003724_increased_susceptibility_to2.88285134
8MP0002063_abnormal_learning/memory/cond2.77278250
9MP0002064_seizures2.65355662
10MP0005423_abnormal_somatic_nervous2.57471185
11MP0001968_abnormal_touch/_nociception2.57229338
12MP0002735_abnormal_chemical_nociception2.53182793
13MP0001486_abnormal_startle_reflex2.50533864
14MP0002572_abnormal_emotion/affect_behav2.49433066
15MP0002734_abnormal_mechanical_nocicepti2.46400043
16MP0002272_abnormal_nervous_system2.41721516
17MP0001501_abnormal_sleep_pattern2.32514259
18MP0002822_catalepsy2.09604309
19MP0002837_dystrophic_cardiac_calcinosis1.97826322
20MP0001188_hyperpigmentation1.95817665
21MP0003828_pulmonary_edema1.94960659
22MP0001440_abnormal_grooming_behavior1.94873876
23MP0002736_abnormal_nociception_after1.94152954
24MP0002067_abnormal_sensory_capabilities1.92623015
25MP0009780_abnormal_chondrocyte_physiolo1.90385916
26MP0005646_abnormal_pituitary_gland1.88078789
27MP0003787_abnormal_imprinting1.87950205
28MP0000751_myopathy1.86946761
29MP0008569_lethality_at_weaning1.84320433
30MP0004215_abnormal_myocardial_fiber1.80671681
31MP0005645_abnormal_hypothalamus_physiol1.80565705
32MP0001970_abnormal_pain_threshold1.78235308
33MP0002733_abnormal_thermal_nociception1.76432496
34MP0006276_abnormal_autonomic_nervous1.75412965
35MP0004145_abnormal_muscle_electrophysio1.71498068
36MP0003303_peritoneal_inflammation1.71465830
37MP0004924_abnormal_behavior1.67667446
38MP0005386_behavior/neurological_phenoty1.67667446
39MP0002184_abnormal_innervation1.66600071
40MP0001984_abnormal_olfaction1.65756729
41MP0000778_abnormal_nervous_system1.60064841
42MP0002557_abnormal_social/conspecific_i1.57266281
43MP0003646_muscle_fatigue1.53220737
44MP0002909_abnormal_adrenal_gland1.47728951
45MP0003172_abnormal_lysosome_physiology1.33210239
46MP0003879_abnormal_hair_cell1.30646523
47MP0004142_abnormal_muscle_tone1.29565200
48MP0000569_abnormal_digit_pigmentation1.27882258
49MP0005409_darkened_coat_color1.27535848
50MP0004484_altered_response_of1.27363730
51MP0000955_abnormal_spinal_cord1.27320967
52MP0004811_abnormal_neuron_physiology1.26411671
53MP0004858_abnormal_nervous_system1.25472964
54MP0003633_abnormal_nervous_system1.25442859
55MP0001502_abnormal_circadian_rhythm1.25179842
56MP0004085_abnormal_heartbeat1.24006804
57MP0005670_abnormal_white_adipose1.23785028
58MP0002882_abnormal_neuron_morphology1.22302978
59MP0003137_abnormal_impulse_conducting1.21618182
60MP0002106_abnormal_muscle_physiology1.21448899
61MP0004087_abnormal_muscle_fiber1.21221189
62MP0002066_abnormal_motor_capabilities/c1.18045935
63MP0002127_abnormal_cardiovascular_syste1.13176649
64MP0003122_maternal_imprinting1.10496786
65MP0001905_abnormal_dopamine_level1.07534845
66MP0003183_abnormal_peptide_metabolism1.06913539
67MP0005551_abnormal_eye_electrophysiolog1.06832186
68MP0003690_abnormal_glial_cell1.06706662
69MP0003045_fibrosis1.06340202
70MP0005171_absent_coat_pigmentation1.05310101
71MP0004130_abnormal_muscle_cell1.03566757
72MP0005167_abnormal_blood-brain_barrier1.03467240
73MP0002876_abnormal_thyroid_physiology1.02667374
74MP0004742_abnormal_vestibular_system1.02561459
75MP0004883_abnormal_blood_vessel1.02266203
76MP0005620_abnormal_muscle_contractility1.01241515
77MP0005385_cardiovascular_system_phenoty1.01136012
78MP0001544_abnormal_cardiovascular_syste1.01136012
79MP0005369_muscle_phenotype1.00746301
80MP0003631_nervous_system_phenotype1.00581382
81MP0002009_preneoplasia1.00200956
82MP0001958_emphysema0.99087191
83MP0005174_abnormal_tail_pigmentation0.98837835
84MP0000749_muscle_degeneration0.97453751
85MP0004036_abnormal_muscle_relaxation0.97357676
86MP0004885_abnormal_endolymph0.95834764
87MP0005535_abnormal_body_temperature0.92921888
88MP0002638_abnormal_pupillary_reflex0.92526432
89MP0004510_myositis0.91961754
90MP0010630_abnormal_cardiac_muscle0.91959935
91MP0001986_abnormal_taste_sensitivity0.91331084
92MP0001529_abnormal_vocalization0.90827995
93MP0002229_neurodegeneration0.87532330
94MP0002972_abnormal_cardiac_muscle0.87282597
95MP0004084_abnormal_cardiac_muscle0.86009139
96MP0000013_abnormal_adipose_tissue0.85638817
97MP0003221_abnormal_cardiomyocyte_apopto0.85441890
98MP0002419_abnormal_innate_immunity0.85288746
99MP0000465_gastrointestinal_hemorrhage0.85230827
100MP0001177_atelectasis0.85075496
101MP0002152_abnormal_brain_morphology0.84860795
102MP0001963_abnormal_hearing_physiology0.84825207
103MP0003656_abnormal_erythrocyte_physiolo0.83980721
104MP0000759_abnormal_skeletal_muscle0.83757450
105MP0010386_abnormal_urinary_bladder0.83495805
106MP0000747_muscle_weakness0.81010896
107MP0003300_gastrointestinal_ulcer0.80844549
108MP0002269_muscular_atrophy0.79311825
109MP0000604_amyloidosis0.79243860
110MP0004381_abnormal_hair_follicle0.78780781
111MP0003329_amyloid_beta_deposits0.78299606
112MP0008961_abnormal_basal_metabolism0.77774162
113MP0001835_abnormal_antigen_presentation0.77555338
114MP0003436_decreased_susceptibility_to0.77434027
115MP0000230_abnormal_systemic_arterial0.77105872
116MP0003632_abnormal_nervous_system0.76923536
117MP0002752_abnormal_somatic_nervous0.75697775
118MP0002069_abnormal_eating/drinking_beha0.74860899
119MP0000015_abnormal_ear_pigmentation0.73607838
120MP0002133_abnormal_respiratory_system0.71872266
121MP0001299_abnormal_eye_distance/0.70790721
122MP0003634_abnormal_glial_cell0.69835668
123MP0005330_cardiomyopathy0.69649283
124MP0001485_abnormal_pinna_reflex0.69543756
125MP0008874_decreased_physiological_sensi0.68859469
126MP0000920_abnormal_myelination0.67486945
127MP0000631_abnormal_neuroendocrine_gland0.63168198
128MP0008775_abnormal_heart_ventricle0.63146886
129MP0008872_abnormal_physiological_respon0.61229697
130MP0006292_abnormal_olfactory_placode0.61152263
131MP0002332_abnormal_exercise_endurance0.61023844
132MP0006138_congestive_heart_failure0.59884991

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.04937256
2Focal seizures (HP:0007359)5.13338891
3Myokymia (HP:0002411)5.02345983
4Febrile seizures (HP:0002373)4.96958510
5Epileptic encephalopathy (HP:0200134)4.49195085
6Progressive cerebellar ataxia (HP:0002073)4.29455515
7Broad-based gait (HP:0002136)4.05680442
8Atonic seizures (HP:0010819)4.01887488
9Visual hallucinations (HP:0002367)3.84234151
10Action tremor (HP:0002345)3.68092244
11Gaze-evoked nystagmus (HP:0000640)3.56354766
12Hyporeflexia of lower limbs (HP:0002600)3.49579023
13Muscle fiber splitting (HP:0003555)3.47851384
14Difficulty running (HP:0009046)3.46184544
15Absence seizures (HP:0002121)3.42938995
16Generalized tonic-clonic seizures (HP:0002069)3.41865583
17Dialeptic seizures (HP:0011146)3.20020648
18Prolonged QT interval (HP:0001657)3.12807586
19Sudden death (HP:0001699)3.00774473
20Dysdiadochokinesis (HP:0002075)2.90000275
21Abnormality of the left ventricular outflow tract (HP:0011103)2.89810832
22Subaortic stenosis (HP:0001682)2.89810832
23Atrial fibrillation (HP:0005110)2.87811699
24Hyperventilation (HP:0002883)2.86119006
25Poor eye contact (HP:0000817)2.83021716
26Optic neuritis (HP:0100653)2.80738375
27Retrobulbar optic neuritis (HP:0100654)2.80738375
28Abnormal EKG (HP:0003115)2.78555197
29Syncope (HP:0001279)2.78356454
30Primary atrial arrhythmia (HP:0001692)2.77933046
31Muscle fiber inclusion bodies (HP:0100299)2.75078884
32Hemiparesis (HP:0001269)2.73628320
33Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.71547450
34Spontaneous hematomas (HP:0007420)2.68582145
35Truncal ataxia (HP:0002078)2.68345976
36Myositis (HP:0100614)2.67623689
37Genetic anticipation (HP:0003743)2.66574609
38Dysmetria (HP:0001310)2.66324209
39Orchitis (HP:0100796)2.65914672
40Asymmetric septal hypertrophy (HP:0001670)2.64504756
41Nemaline bodies (HP:0003798)2.62548700
42Postural instability (HP:0002172)2.61852398
43Drooling (HP:0002307)2.61426170
44Excessive salivation (HP:0003781)2.61426170
45Supraventricular tachycardia (HP:0004755)2.56356887
46EMG: neuropathic changes (HP:0003445)2.54208645
47Anxiety (HP:0000739)2.51253243
48Impaired social interactions (HP:0000735)2.49896713
49Abnormal social behavior (HP:0012433)2.49896713
50Supraventricular arrhythmia (HP:0005115)2.49643416
51Bradycardia (HP:0001662)2.49450748
52Fetal akinesia sequence (HP:0001989)2.49135123
53Amblyopia (HP:0000646)2.46581601
54Type 1 muscle fiber predominance (HP:0003803)2.46537671
55Hemiplegia (HP:0002301)2.46298050
56Ventricular fibrillation (HP:0001663)2.44955336
57Abnormal eating behavior (HP:0100738)2.43554111
58Ventricular tachycardia (HP:0004756)2.43225509
59Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.43223946
60Supranuclear gaze palsy (HP:0000605)2.43158223
61Frequent falls (HP:0002359)2.42952427
62Abnormality of binocular vision (HP:0011514)2.40669257
63Diplopia (HP:0000651)2.40669257
64Mutism (HP:0002300)2.38860905
65Scanning speech (HP:0002168)2.38309257
66Depression (HP:0000716)2.36493441
67Urinary bladder sphincter dysfunction (HP:0002839)2.35946716
68Eczematoid dermatitis (HP:0000976)2.35740203
69Absent speech (HP:0001344)2.34965075
70EMG: myopathic abnormalities (HP:0003458)2.34029578
71Calf muscle hypertrophy (HP:0008981)2.33857387
72Lower limb amyotrophy (HP:0007210)2.30901642
73Ankle clonus (HP:0011448)2.30375449
74Recurrent bacterial skin infections (HP:0005406)2.30346714
75Bundle branch block (HP:0011710)2.30025993
76Muscle hypertrophy of the lower extremities (HP:0008968)2.26700077
77Impaired smooth pursuit (HP:0007772)2.26473121
78Gastrointestinal infarctions (HP:0005244)2.23304516
79Dysmetric saccades (HP:0000641)2.21884117
80Recurrent gram-negative bacterial infections (HP:0005420)2.21831397
81Exercise-induced myalgia (HP:0003738)2.21440026
82Impaired vibration sensation in the lower limbs (HP:0002166)2.21357220
83Aplasia involving bones of the extremities (HP:0009825)2.17015611
84Aplasia involving bones of the upper limbs (HP:0009823)2.17015611
85Aplasia of the phalanges of the hand (HP:0009802)2.17015611
86Abnormality of the calf musculature (HP:0001430)2.16142027
87Protruding tongue (HP:0010808)2.14273615
88Aortic aneurysm (HP:0004942)2.13826044
89Recurrent abscess formation (HP:0002722)2.13171078
90Peritonitis (HP:0002586)2.12236050
91Stomatitis (HP:0010280)2.07847306
92Heart block (HP:0012722)2.05853751
93Abnormal hair whorl (HP:0010721)2.05352080
94Progressive inability to walk (HP:0002505)2.04792914
95Epileptiform EEG discharges (HP:0011182)2.03255367
96Central scotoma (HP:0000603)2.01863151
97Obstructive sleep apnea (HP:0002870)1.99781460
98Keratoconjunctivitis sicca (HP:0001097)1.99298084
99Incomplete penetrance (HP:0003829)1.98695306
100Increased variability in muscle fiber diameter (HP:0003557)1.97619896
101Facial diplegia (HP:0001349)1.94359736
102Keratoconjunctivitis (HP:0001096)1.94357296
103Abnormality of ocular smooth pursuit (HP:0000617)1.93777289
104Stereotypic behavior (HP:0000733)1.93772673
105Aqueductal stenosis (HP:0002410)1.93234369
106Papillary thyroid carcinoma (HP:0002895)1.90452137
107Abnormality of salivation (HP:0100755)1.89924289
108Chest pain (HP:0100749)1.89528133
109Spastic gait (HP:0002064)1.89271061
110Vertigo (HP:0002321)1.89185704
111Hypochromic microcytic anemia (HP:0004840)1.88594245
112Pheochromocytoma (HP:0002666)1.88037050
113Intention tremor (HP:0002080)1.87618107
114Lipoatrophy (HP:0100578)1.87557496
115Lower limb muscle weakness (HP:0007340)1.87398604
116Gingivitis (HP:0000230)1.86377085
117Myotonia (HP:0002486)1.85526421
118EEG with generalized epileptiform discharges (HP:0011198)1.85484865
119Inability to walk (HP:0002540)1.84964030
120Bradykinesia (HP:0002067)1.83172890
121Blue irides (HP:0000635)1.83111254
122Hematochezia (HP:0002573)1.82553249
123Abnormality of the endocardium (HP:0004306)1.81852732
124Abnormality of the foot musculature (HP:0001436)1.81229045
125Hemoptysis (HP:0002105)1.81211082
126Exotropia (HP:0000577)1.80826986
127Limb dystonia (HP:0002451)1.80390725
128Abnormality of the nasal septum (HP:0000419)1.78158258
129Foot dorsiflexor weakness (HP:0009027)1.77618118
130Ventricular arrhythmia (HP:0004308)1.77131572
131Papilledema (HP:0001085)1.77056619
132Polyphagia (HP:0002591)1.76822885
133Hyperkalemia (HP:0002153)1.76685131
134Abnormality of skeletal muscle fiber size (HP:0012084)1.76210450
135Neoplasm of the heart (HP:0100544)1.75798092
136Distal arthrogryposis (HP:0005684)1.75664411
137Abnormal atrioventricular conduction (HP:0005150)1.73853219
138Gingival bleeding (HP:0000225)1.72376727
139Retinal dysplasia (HP:0007973)1.70284781
140Dynein arm defect of respiratory motile cilia (HP:0012255)1.69203995
141Absent/shortened dynein arms (HP:0200106)1.69203995
142Steppage gait (HP:0003376)1.69178479
143Distal lower limb amyotrophy (HP:0008944)1.66659625
144Deeply set eye (HP:0000490)1.66620673
145Hypsarrhythmia (HP:0002521)1.66166874
146Urinary urgency (HP:0000012)1.65513960
147Impaired vibratory sensation (HP:0002495)1.64692295
148Left ventricular hypertrophy (HP:0001712)1.64662015
149Generalized hypopigmentation of hair (HP:0011358)1.64608028
150Widely spaced teeth (HP:0000687)1.63850949

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.50795396
2EPHA43.38534550
3CASK3.09057989
4MARK13.06618635
5FRK3.03389970
6MAP2K72.55632673
7TNIK2.44099437
8MAP3K42.43257133
9MAP3K92.17957227
10PRPF4B2.11110035
11MINK12.04146962
12NTRK21.98639405
13RIPK41.86772364
14DAPK21.86362989
15BLK1.77545633
16MAPK131.75315543
17PHKG21.74201175
18PHKG11.74201175
19INSRR1.64414570
20PIK3CG1.62166689
21SGK21.48311573
22MAP3K121.47428648
23CAMK1G1.46002195
24STK381.43288294
25PAK61.43181101
26CDK51.33273185
27MAP2K41.32538109
28GRK51.24644900
29SGK2231.22974922
30SGK4941.22974922
31PLK21.22377888
32PRKD31.20956435
33PINK11.19822743
34LMTK21.19260087
35TTN1.18688148
36MUSK1.17515989
37CAMKK21.15430257
38SIK21.14415145
39CAMKK11.14076301
40CAMK2A1.13723959
41FGFR31.12420150
42CAMK11.12220243
43MAP2K31.12058119
44NEK61.10337088
45PRKCG1.09372115
46SGK31.08073815
47NTRK11.07739930
48TAOK31.06815392
49EPHA31.06398802
50FES1.04683019
51CAMK1D1.03554385
52AKT31.03066162
53DMPK1.01624637
54PNCK1.00909409
55GRK71.00118361
56IRAK10.97048224
57SYK0.96917221
58MARK20.95638111
59SGK10.95503988
60TRPM70.94903319
61DAPK10.94071592
62BMPR20.93833618
63TXK0.91798026
64PRKCE0.90852516
65OBSCN0.90257730
66CSK0.89117045
67JAK10.88172772
68KSR10.86493996
69SIK30.85164296
70STK110.84167509
71JAK20.84127249
72NLK0.83917059
73PRKCH0.82914863
74IRAK40.81857322
75EPHB10.81287564
76CDC42BPA0.80746567
77CAMK2B0.80241686
78HCK0.79199640
79TGFBR20.78953762
80TNK20.78688150
81TEC0.76735414
82CAMK2D0.76564349
83TYK20.75662071
84KIT0.74619798
85TAOK10.74204956
86MAP3K10.73722010
87WNK10.72081588
88GRK60.72067812
89ZAP700.70531564
90MAP3K20.69928109
91MAPK120.68721227
92UHMK10.68512232
93PKN10.68440011
94MAP3K50.68299579
95PTK2B0.68285247
96RET0.67386460
97ITK0.66861989
98IKBKE0.65645304
99PIK3CA0.65461309
100TIE10.65137680
101CAMK40.64449292
102PRKD10.62973819
103DYRK1A0.61299051
104FGR0.60711429
105MAP3K130.60636371
106CDK30.59388625
107BTK0.59030377
108MAP2K60.58513265
109FGFR20.58174414
110KSR20.57214138
111OXSR10.55953738
112PAK30.55929151
113RPS6KA30.52798706
114MAP3K60.49894873
115PRKG10.49402821
116PDK10.47702028
117MAPK70.47641781
118RIPK10.47154219
119CDK190.47071877
120PDPK10.46804700
121CSNK1G20.46254444
122PRKACA0.45688233
123CAMK2G0.45596370
124MAPK100.45550146
125BCR0.44559048
126MYLK0.43284550
127FER0.42766888
128PRKAA20.42157685
129GRK10.40724334
130PRKAA10.40026053
131ROCK10.39794446
132PRKCZ0.39395210
133IRAK20.37818655
134LATS20.37522756
135FYN0.37081635
136MAP3K70.36806613

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.51955782
2Circadian entrainment_Homo sapiens_hsa047132.64793661
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.57501559
4Olfactory transduction_Homo sapiens_hsa047402.55692618
5Morphine addiction_Homo sapiens_hsa050322.50805206
6Glutamatergic synapse_Homo sapiens_hsa047242.50454393
7GABAergic synapse_Homo sapiens_hsa047272.41169941
8Synaptic vesicle cycle_Homo sapiens_hsa047212.36681282
9Long-term potentiation_Homo sapiens_hsa047202.32740862
10Salivary secretion_Homo sapiens_hsa049702.17011673
11Amphetamine addiction_Homo sapiens_hsa050312.09712078
12Taste transduction_Homo sapiens_hsa047422.01320260
13Insulin secretion_Homo sapiens_hsa049111.98921389
14Dopaminergic synapse_Homo sapiens_hsa047281.87602832
15Renin secretion_Homo sapiens_hsa049241.87177300
16Cholinergic synapse_Homo sapiens_hsa047251.83132775
17Calcium signaling pathway_Homo sapiens_hsa040201.82605228
18Serotonergic synapse_Homo sapiens_hsa047261.78539545
19Gastric acid secretion_Homo sapiens_hsa049711.72909623
20Aldosterone synthesis and secretion_Homo sapiens_hsa049251.71985409
21Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.67378066
22Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.65618162
23Oxytocin signaling pathway_Homo sapiens_hsa049211.61904089
24Long-term depression_Homo sapiens_hsa047301.59097683
25cAMP signaling pathway_Homo sapiens_hsa040241.45809857
26Cocaine addiction_Homo sapiens_hsa050301.45635540
27Type II diabetes mellitus_Homo sapiens_hsa049301.42566136
28Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.38353111
29Dilated cardiomyopathy_Homo sapiens_hsa054141.34774470
30Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.34322591
31Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.32102885
32GnRH signaling pathway_Homo sapiens_hsa049121.30725851
33Cardiac muscle contraction_Homo sapiens_hsa042601.29307736
34Phosphatidylinositol signaling system_Homo sapiens_hsa040701.28462192
35cGMP-PKG signaling pathway_Homo sapiens_hsa040221.26363690
36Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.23266608
37Gap junction_Homo sapiens_hsa045401.20109491
38Osteoclast differentiation_Homo sapiens_hsa043801.16747294
39Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.16062319
40Phototransduction_Homo sapiens_hsa047441.15552055
41Axon guidance_Homo sapiens_hsa043601.10930325
42Vascular smooth muscle contraction_Homo sapiens_hsa042701.09303949
43B cell receptor signaling pathway_Homo sapiens_hsa046621.04741173
44Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.03707294
45Pancreatic secretion_Homo sapiens_hsa049721.02969215
46Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.01257142
47Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.00425411
48Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.00141505
49Collecting duct acid secretion_Homo sapiens_hsa049660.96543362
50Melanogenesis_Homo sapiens_hsa049160.96138077
51Estrogen signaling pathway_Homo sapiens_hsa049150.95120989
52Dorso-ventral axis formation_Homo sapiens_hsa043200.93144528
53Leishmaniasis_Homo sapiens_hsa051400.92391454
54Phospholipase D signaling pathway_Homo sapiens_hsa040720.89517343
55ErbB signaling pathway_Homo sapiens_hsa040120.89004377
56Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.83546395
57Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.82170063
58Tuberculosis_Homo sapiens_hsa051520.82005616
59Insulin resistance_Homo sapiens_hsa049310.81855291
60Glioma_Homo sapiens_hsa052140.81561882
61Circadian rhythm_Homo sapiens_hsa047100.80826167
62FoxO signaling pathway_Homo sapiens_hsa040680.80692372
63Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.80217323
64MAPK signaling pathway_Homo sapiens_hsa040100.78325006
65Choline metabolism in cancer_Homo sapiens_hsa052310.77326650
66Prolactin signaling pathway_Homo sapiens_hsa049170.75940571
67Staphylococcus aureus infection_Homo sapiens_hsa051500.74461627
68Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.74018173
69Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.73958654
70Non-small cell lung cancer_Homo sapiens_hsa052230.72841160
71Ras signaling pathway_Homo sapiens_hsa040140.72057639
72Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.71357579
73Inositol phosphate metabolism_Homo sapiens_hsa005620.70489682
74Fatty acid biosynthesis_Homo sapiens_hsa000610.70241913
75T cell receptor signaling pathway_Homo sapiens_hsa046600.70145009
76Jak-STAT signaling pathway_Homo sapiens_hsa046300.70051353
77AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.67308646
78ABC transporters_Homo sapiens_hsa020100.67265016
79Rap1 signaling pathway_Homo sapiens_hsa040150.66835591
80NOD-like receptor signaling pathway_Homo sapiens_hsa046210.66618195
81Leukocyte transendothelial migration_Homo sapiens_hsa046700.65353885
82Thyroid hormone synthesis_Homo sapiens_hsa049180.64955942
83Thyroid hormone signaling pathway_Homo sapiens_hsa049190.64682982
84Glucagon signaling pathway_Homo sapiens_hsa049220.64153131
85Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.63266812
86Regulation of autophagy_Homo sapiens_hsa041400.60262022
87Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.60068935
88Toll-like receptor signaling pathway_Homo sapiens_hsa046200.59897255
89Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.59207811
90Sphingolipid signaling pathway_Homo sapiens_hsa040710.58204482
91Amoebiasis_Homo sapiens_hsa051460.57653419
92Malaria_Homo sapiens_hsa051440.57421651
93Focal adhesion_Homo sapiens_hsa045100.57196643
94Longevity regulating pathway - mammal_Homo sapiens_hsa042110.57026643
95Ovarian steroidogenesis_Homo sapiens_hsa049130.56900311
96Insulin signaling pathway_Homo sapiens_hsa049100.56193087
97Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.56014879
98Carbohydrate digestion and absorption_Homo sapiens_hsa049730.55868450
99African trypanosomiasis_Homo sapiens_hsa051430.55538201
100Acute myeloid leukemia_Homo sapiens_hsa052210.55460692
101Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.54269442
102Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.52691949
103Neurotrophin signaling pathway_Homo sapiens_hsa047220.49311212
104Alzheimers disease_Homo sapiens_hsa050100.48936703
105Vibrio cholerae infection_Homo sapiens_hsa051100.48539942
106Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.47051547
107Wnt signaling pathway_Homo sapiens_hsa043100.46851337
108Chemokine signaling pathway_Homo sapiens_hsa040620.46788453
109Oocyte meiosis_Homo sapiens_hsa041140.45405361
110Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.45257103
111VEGF signaling pathway_Homo sapiens_hsa043700.40136207
112SNARE interactions in vesicular transport_Homo sapiens_hsa041300.37470642
113mTOR signaling pathway_Homo sapiens_hsa041500.35823713
114Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.35608995
115Endocytosis_Homo sapiens_hsa041440.35481440
116Platelet activation_Homo sapiens_hsa046110.34612683
117Endometrial cancer_Homo sapiens_hsa052130.33531725
118Sphingolipid metabolism_Homo sapiens_hsa006000.33205667
119Regulation of actin cytoskeleton_Homo sapiens_hsa048100.31057303
120Glycerophospholipid metabolism_Homo sapiens_hsa005640.30380981
121Renal cell carcinoma_Homo sapiens_hsa052110.30290889
122AMPK signaling pathway_Homo sapiens_hsa041520.29816689
123Adipocytokine signaling pathway_Homo sapiens_hsa049200.29371450
124Melanoma_Homo sapiens_hsa052180.28505836
125Type I diabetes mellitus_Homo sapiens_hsa049400.27114072
126Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.27026169

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