FSD1L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)5.29328392
2epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)5.10385342
3cilium or flagellum-dependent cell motility (GO:0001539)4.46361442
4regulation of short-term neuronal synaptic plasticity (GO:0048172)4.43264119
5nucleobase catabolic process (GO:0046113)4.41086356
6epithelial cilium movement (GO:0003351)4.38364244
7neuron cell-cell adhesion (GO:0007158)4.34519844
8axonemal dynein complex assembly (GO:0070286)4.25175167
9cilium movement (GO:0003341)4.12937588
10behavioral response to nicotine (GO:0035095)3.96365814
11protein localization to synapse (GO:0035418)3.93345180
12neuron recognition (GO:0008038)3.85827559
13positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.78850319
14vocalization behavior (GO:0071625)3.74430516
15protein localization to cilium (GO:0061512)3.70196338
16positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.69308321
17cell migration in hindbrain (GO:0021535)3.63128988
18presynaptic membrane assembly (GO:0097105)3.62729025
19axonal fasciculation (GO:0007413)3.62172447
20regulation of rhodopsin mediated signaling pathway (GO:0022400)3.61279072
21synaptic vesicle maturation (GO:0016188)3.56248486
22presynaptic membrane organization (GO:0097090)3.56056263
23positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.55511849
24regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.54223758
25rhodopsin mediated signaling pathway (GO:0016056)3.49975830
26regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.48150196
27synaptic vesicle exocytosis (GO:0016079)3.44472631
28regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.41402989
29serotonin metabolic process (GO:0042428)3.38992309
30glutamate secretion (GO:0014047)3.37326420
31establishment of mitochondrion localization (GO:0051654)3.36827432
32regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.33189076
33layer formation in cerebral cortex (GO:0021819)3.33177042
34nonmotile primary cilium assembly (GO:0035058)3.28372284
35regulation of synaptic vesicle exocytosis (GO:2000300)3.26863235
36regulation of heat generation (GO:0031650)3.26153031
37ionotropic glutamate receptor signaling pathway (GO:0035235)3.23284714
38dendritic spine morphogenesis (GO:0060997)3.22666042
39membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.22533241
40primary amino compound metabolic process (GO:1901160)3.21045000
41regulation of glutamate receptor signaling pathway (GO:1900449)3.19106671
42kynurenine metabolic process (GO:0070189)3.18642656
43gamma-aminobutyric acid transport (GO:0015812)3.17405411
44intraciliary transport (GO:0042073)3.17068689
45regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)3.16694894
46central nervous system neuron axonogenesis (GO:0021955)3.16692294
47dendrite morphogenesis (GO:0048813)3.15585320
48cilium assembly (GO:0042384)3.14558893
49neuronal action potential propagation (GO:0019227)3.14181865
50cilium organization (GO:0044782)3.13688572
51locomotory exploration behavior (GO:0035641)3.10370117
52synaptic transmission, glutamatergic (GO:0035249)3.09890420
53positive regulation of heat generation (GO:0031652)3.09613043
54retinal cone cell development (GO:0046549)3.08310726
55mitochondrion transport along microtubule (GO:0047497)3.08103606
56establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.08103606
57regulation of fever generation (GO:0031620)3.07293077
58tryptophan catabolic process (GO:0006569)3.06309344
59indole-containing compound catabolic process (GO:0042436)3.06309344
60indolalkylamine catabolic process (GO:0046218)3.06309344
61glutamate receptor signaling pathway (GO:0007215)3.05476932
62positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.05425571
63cerebellar Purkinje cell differentiation (GO:0021702)3.05351335
64retinal ganglion cell axon guidance (GO:0031290)3.05274987
65regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.04363161
66innervation (GO:0060384)3.03770229
67detection of calcium ion (GO:0005513)3.01870419
68central nervous system projection neuron axonogenesis (GO:0021952)3.01819127
69hindbrain development (GO:0030902)3.00811758
70neuron-neuron synaptic transmission (GO:0007270)2.99909905
71regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.99766397
72proline transport (GO:0015824)2.98723585
73synaptic vesicle docking involved in exocytosis (GO:0016081)2.97065275
74postsynaptic membrane organization (GO:0001941)2.96861624
75positive regulation of potassium ion transmembrane transport (GO:1901381)2.96737911
76regulation of cilium movement (GO:0003352)2.95412745
77synapse assembly (GO:0007416)2.95159964
78regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.94970264
79membrane depolarization during action potential (GO:0086010)2.94745075
80photoreceptor cell differentiation (GO:0046530)2.94743718
81eye photoreceptor cell differentiation (GO:0001754)2.94743718
82neuron fate determination (GO:0048664)2.93494133
83negative regulation of dendrite development (GO:2000171)2.91822281
84regulation of synaptic vesicle transport (GO:1902803)2.91628863
85limb bud formation (GO:0060174)2.91467187
86neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.90260015
87regulation of cell communication by electrical coupling (GO:0010649)2.87142016
88negative regulation of synaptic transmission, GABAergic (GO:0032229)2.85705394
89indolalkylamine metabolic process (GO:0006586)2.83740449
90startle response (GO:0001964)2.83686690
91cilium morphogenesis (GO:0060271)2.82969812
92regulation of synaptic transmission, glutamatergic (GO:0051966)2.82012717
93regulation of glutamate secretion (GO:0014048)2.81917139
94cerebral cortex radially oriented cell migration (GO:0021799)2.81166434
95synaptic transmission, cholinergic (GO:0007271)2.80423413
96cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.80380817
97negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.80369280
98regulation of collateral sprouting (GO:0048670)2.80173842
99positive regulation of amino acid transport (GO:0051957)2.78714350
100organelle transport along microtubule (GO:0072384)2.78414321
101indole-containing compound metabolic process (GO:0042430)2.77890864
102axoneme assembly (GO:0035082)2.77685721
103axon extension (GO:0048675)2.77545902
104auditory behavior (GO:0031223)2.76637133
105establishment of nucleus localization (GO:0040023)2.76174458
106negative regulation of cytosolic calcium ion concentration (GO:0051481)2.75371101
107regulation of neuronal synaptic plasticity (GO:0048168)2.73992811
108neurotransmitter secretion (GO:0007269)2.73768891
109cell communication by electrical coupling (GO:0010644)2.73448292
110regulation of synapse structural plasticity (GO:0051823)2.73273764
111positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.72972543
112response to auditory stimulus (GO:0010996)2.72629050
113forebrain neuron differentiation (GO:0021879)2.72589624
114positive regulation of synapse assembly (GO:0051965)2.72161758
115membrane hyperpolarization (GO:0060081)2.71597878
116regulation of membrane repolarization (GO:0060306)2.71072070
117photoreceptor cell maintenance (GO:0045494)2.70746331
118exploration behavior (GO:0035640)2.69808604
119regulation of excitatory postsynaptic membrane potential (GO:0060079)2.69487620
120response to pheromone (GO:0019236)2.69187465
121regulation of postsynaptic membrane potential (GO:0060078)2.68175701
122photoreceptor cell development (GO:0042461)2.67179304
123cell communication involved in cardiac conduction (GO:0086065)2.66498274
124regulation of synapse assembly (GO:0051963)2.66424796
125regulation of voltage-gated calcium channel activity (GO:1901385)2.66067340
126transmission of nerve impulse (GO:0019226)2.65280836
127neurotransmitter-gated ion channel clustering (GO:0072578)2.64950893
128response to amphetamine (GO:0001975)2.63988840
129neural tube formation (GO:0001841)2.63922198
130glycosphingolipid biosynthetic process (GO:0006688)2.62760488
131eye photoreceptor cell development (GO:0042462)2.62375722
132cellular component assembly involved in morphogenesis (GO:0010927)2.61162832
133cAMP catabolic process (GO:0006198)2.60894332
134regulation of long-term neuronal synaptic plasticity (GO:0048169)2.60864777
135negative regulation of amino acid transport (GO:0051956)2.60760837
136G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.60237372
137synapse organization (GO:0050808)2.60165341
138regulation of neurotransmitter secretion (GO:0046928)2.59944787
139neuronal stem cell maintenance (GO:0097150)2.59872574
140prepulse inhibition (GO:0060134)2.59478874
141vesicle transport along microtubule (GO:0047496)2.58299400
142neuromuscular synaptic transmission (GO:0007274)2.57766685
143dendrite development (GO:0016358)2.57431756
144neuronal action potential (GO:0019228)2.57302980
145motile cilium assembly (GO:0044458)2.56337359
146positive regulation of potassium ion transport (GO:0043268)2.55903539
147regulation of respiratory system process (GO:0044065)2.55785246
148mechanosensory behavior (GO:0007638)2.55698740
149regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.54948292
150synaptic vesicle endocytosis (GO:0048488)2.54598537
151neurotransmitter transport (GO:0006836)2.53471581
152membrane depolarization (GO:0051899)2.53309060
153adult walking behavior (GO:0007628)2.53299770
154positive regulation of dendritic spine morphogenesis (GO:0061003)2.52833696
155protein polyglutamylation (GO:0018095)2.52468541
156negative regulation of systemic arterial blood pressure (GO:0003085)2.52211979
157olfactory bulb development (GO:0021772)2.52189397
158central nervous system myelination (GO:0022010)2.48036108
159axon ensheathment in central nervous system (GO:0032291)2.48036108
160calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.47866004
161behavioral defense response (GO:0002209)2.47856095

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.92702529
2GBX2_23144817_ChIP-Seq_PC3_Human3.96601411
3* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.54874203
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.42217744
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.41697830
6EZH2_27304074_Chip-Seq_ESCs_Mouse2.32230811
7TAF15_26573619_Chip-Seq_HEK293_Human2.22915014
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.21196271
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.13667838
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.13667838
11ZFP57_27257070_Chip-Seq_ESCs_Mouse2.10486031
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.08550798
13ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.08389938
14SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.07342856
15REST_21632747_ChIP-Seq_MESCs_Mouse2.05315764
16SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.05167505
17CTBP2_25329375_ChIP-Seq_LNCAP_Human2.04311711
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.00371998
19EED_16625203_ChIP-ChIP_MESCs_Mouse1.99120792
20POU3F2_20337985_ChIP-ChIP_501MEL_Human1.96256657
21* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.89644386
22* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.88564388
23CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.88138251
24SMAD4_21799915_ChIP-Seq_A2780_Human1.87977268
25SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.87279479
26EZH2_27294783_Chip-Seq_ESCs_Mouse1.84739475
27CTBP1_25329375_ChIP-Seq_LNCAP_Human1.84552994
28PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.84449668
29RNF2_27304074_Chip-Seq_ESCs_Mouse1.84325542
30P300_19829295_ChIP-Seq_ESCs_Human1.83018921
31IGF1R_20145208_ChIP-Seq_DFB_Human1.81535648
32DROSHA_22980978_ChIP-Seq_HELA_Human1.80020301
33BMI1_23680149_ChIP-Seq_NPCS_Mouse1.78648594
34GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.76430925
35SUZ12_27294783_Chip-Seq_ESCs_Mouse1.72620947
36CBX2_27304074_Chip-Seq_ESCs_Mouse1.69633461
37AR_21572438_ChIP-Seq_LNCaP_Human1.69340517
38CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.66735930
39RBPJ_22232070_ChIP-Seq_NCS_Mouse1.66337870
40HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.65922644
41OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.65642223
42PIAS1_25552417_ChIP-Seq_VCAP_Human1.58976125
43SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.58065697
44FUS_26573619_Chip-Seq_HEK293_Human1.57628651
45VDR_22108803_ChIP-Seq_LS180_Human1.56806255
46SMAD3_21741376_ChIP-Seq_EPCs_Human1.56650231
47REST_18959480_ChIP-ChIP_MESCs_Mouse1.53229017
48TOP2B_26459242_ChIP-Seq_MCF-7_Human1.53118628
49* STAT3_23295773_ChIP-Seq_U87_Human1.51376596
50ZNF274_21170338_ChIP-Seq_K562_Hela1.50989992
51RNF2_27304074_Chip-Seq_NSC_Mouse1.47683779
52RARB_27405468_Chip-Seq_BRAIN_Mouse1.47385270
53CDX2_19796622_ChIP-Seq_MESCs_Mouse1.47082627
54RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.46743318
55AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.44374398
56SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.42886153
57NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.41371038
58CBP_20019798_ChIP-Seq_JUKART_Human1.40821391
59IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.40821391
60PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.38998358
61TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.35642717
62SOX2_21211035_ChIP-Seq_LN229_Gbm1.35122480
63* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.34594689
64NR3C1_23031785_ChIP-Seq_PC12_Mouse1.33242138
65ER_23166858_ChIP-Seq_MCF-7_Human1.29847570
66SUZ12_27294783_Chip-Seq_NPCs_Mouse1.29572410
67* TCF4_23295773_ChIP-Seq_U87_Human1.28800409
68ARNT_22903824_ChIP-Seq_MCF-7_Human1.28769722
69AR_25329375_ChIP-Seq_VCAP_Human1.26614584
70SMAD_19615063_ChIP-ChIP_OVARY_Human1.25963444
71* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.24990312
72TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24737503
73POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.24737503
74MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.24456786
75CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24365627
76* NANOG_18555785_Chip-Seq_ESCs_Mouse1.23618965
77EP300_21415370_ChIP-Seq_HL-1_Mouse1.23495965
78EWS_26573619_Chip-Seq_HEK293_Human1.22100740
79AHR_22903824_ChIP-Seq_MCF-7_Human1.21511138
80MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.21302770
81TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.21141631
82TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20249666
83EZH2_27294783_Chip-Seq_NPCs_Mouse1.19867613
84PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.19768774
85YAP1_20516196_ChIP-Seq_MESCs_Mouse1.19288751
86TAL1_26923725_Chip-Seq_HPCs_Mouse1.18258901
87FLI1_21867929_ChIP-Seq_TH2_Mouse1.18138205
88TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.17817107
89NR3C1_21868756_ChIP-Seq_MCF10A_Human1.17511767
90P53_22127205_ChIP-Seq_FIBROBLAST_Human1.17390152
91RUNX2_22187159_ChIP-Seq_PCA_Human1.16657209
92SUZ12_18555785_Chip-Seq_ESCs_Mouse1.16093448
93ZNF217_24962896_ChIP-Seq_MCF-7_Human1.15282230
94* E2F1_18555785_Chip-Seq_ESCs_Mouse1.15146481
95EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.13933539
96KLF5_20875108_ChIP-Seq_MESCs_Mouse1.13381004
97SALL1_21062744_ChIP-ChIP_HESCs_Human1.13216883
98NFE2_27457419_Chip-Seq_LIVER_Mouse1.12939176
99RING1B_27294783_Chip-Seq_ESCs_Mouse1.11262640
100PCGF2_27294783_Chip-Seq_ESCs_Mouse1.10366118
101AR_19668381_ChIP-Seq_PC3_Human1.10257643
102TP53_16413492_ChIP-PET_HCT116_Human1.09783667
103TCF4_22108803_ChIP-Seq_LS180_Human1.09685738
104SMAD4_21741376_ChIP-Seq_EPCs_Human1.09560987
105PCGF2_27294783_Chip-Seq_NPCs_Mouse1.09410694
106FLI1_27457419_Chip-Seq_LIVER_Mouse1.09269730
107TP53_18474530_ChIP-ChIP_U2OS_Human1.08943910
108EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.08627608
109CMYC_18555785_Chip-Seq_ESCs_Mouse1.06996132
110* PRDM14_20953172_ChIP-Seq_ESCs_Human1.06860101
111BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.06741590
112RING1B_27294783_Chip-Seq_NPCs_Mouse1.06351162
113BCAT_22108803_ChIP-Seq_LS180_Human1.04128954
114LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03715188
115P53_22387025_ChIP-Seq_ESCs_Mouse1.03506232
116MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01440182

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern3.95425293
2MP0004859_abnormal_synaptic_plasticity3.75171390
3MP0004270_analgesia3.28930954
4MP0003635_abnormal_synaptic_transmissio2.73470840
5MP0005423_abnormal_somatic_nervous2.65752860
6MP0001968_abnormal_touch/_nociception2.60008204
7MP0002735_abnormal_chemical_nociception2.58218523
8MP0005551_abnormal_eye_electrophysiolog2.52366069
9MP0000778_abnormal_nervous_system2.49086765
10MP0002734_abnormal_mechanical_nocicepti2.45785198
11MP0009745_abnormal_behavioral_response2.33656522
12MP0002063_abnormal_learning/memory/cond2.30930915
13MP0001486_abnormal_startle_reflex2.21450054
14MP0006276_abnormal_autonomic_nervous2.18297610
15MP0002064_seizures2.13040967
16MP0002572_abnormal_emotion/affect_behav2.08735265
17MP0003195_calcinosis2.07827740
18MP0002272_abnormal_nervous_system2.05535528
19MP0009046_muscle_twitch2.04299553
20MP0006072_abnormal_retinal_apoptosis2.01219324
21MP0002736_abnormal_nociception_after2.00905585
22MP0004133_heterotaxia1.88381147
23MP0003890_abnormal_embryonic-extraembry1.87961968
24MP0005253_abnormal_eye_physiology1.84273636
25MP0002184_abnormal_innervation1.83559618
26MP0002067_abnormal_sensory_capabilities1.79794579
27MP0001440_abnormal_grooming_behavior1.76334684
28MP0002837_dystrophic_cardiac_calcinosis1.72056417
29MP0002733_abnormal_thermal_nociception1.69936857
30MP0001970_abnormal_pain_threshold1.69225340
31MP0001188_hyperpigmentation1.68682292
32MP0004924_abnormal_behavior1.64516363
33MP0005386_behavior/neurological_phenoty1.64516363
34MP0004215_abnormal_myocardial_fiber1.62720385
35MP0002882_abnormal_neuron_morphology1.60174718
36MP0001984_abnormal_olfaction1.56345362
37MP0002557_abnormal_social/conspecific_i1.56171604
38MP0000751_myopathy1.54704426
39MP0005646_abnormal_pituitary_gland1.51187728
40MP0000955_abnormal_spinal_cord1.49211086
41MP0003787_abnormal_imprinting1.46486940
42MP0005645_abnormal_hypothalamus_physiol1.42753467
43MP0001529_abnormal_vocalization1.42556346
44MP0004858_abnormal_nervous_system1.40999947
45MP0008877_abnormal_DNA_methylation1.40899446
46MP0004811_abnormal_neuron_physiology1.39703013
47MP0000569_abnormal_digit_pigmentation1.37896578
48MP0002638_abnormal_pupillary_reflex1.37197954
49MP0002752_abnormal_somatic_nervous1.35850121
50MP0004043_abnormal_pH_regulation1.35164711
51MP0005187_abnormal_penis_morphology1.35072338
52MP0004145_abnormal_muscle_electrophysio1.33249198
53MP0002229_neurodegeneration1.32806971
54MP0009780_abnormal_chondrocyte_physiolo1.32526481
55MP0004742_abnormal_vestibular_system1.28353550
56MP0000631_abnormal_neuroendocrine_gland1.27945726
57MP0008569_lethality_at_weaning1.26193631
58MP0002332_abnormal_exercise_endurance1.25948094
59MP0001501_abnormal_sleep_pattern1.23226210
60MP0003122_maternal_imprinting1.21241503
61MP0006292_abnormal_olfactory_placode1.19306417
62MP0004885_abnormal_endolymph1.19199925
63MP0001502_abnormal_circadian_rhythm1.18864205
64MP0001986_abnormal_taste_sensitivity1.18379063
65MP0003137_abnormal_impulse_conducting1.18122185
66MP0003646_muscle_fatigue1.17744854
67MP0005195_abnormal_posterior_eye1.15816426
68MP0002066_abnormal_motor_capabilities/c1.14102289
69MP0004085_abnormal_heartbeat1.12256619
70MP0002822_catalepsy1.12226745
71MP0002152_abnormal_brain_morphology1.10127873
72MP0005167_abnormal_blood-brain_barrier1.10085994
73MP0001905_abnormal_dopamine_level1.09974612
74MP0001485_abnormal_pinna_reflex1.09661131
75MP0001963_abnormal_hearing_physiology1.08716521
76MP0005248_abnormal_Harderian_gland1.07495882
77MP0004484_altered_response_of1.04039515
78MP0004142_abnormal_muscle_tone1.03603378
79MP0002751_abnormal_autonomic_nervous1.03057866
80MP0005394_taste/olfaction_phenotype1.02940334
81MP0005499_abnormal_olfactory_system1.02940334
82MP0003634_abnormal_glial_cell0.97732744
83MP0000026_abnormal_inner_ear0.96808882
84MP0001299_abnormal_eye_distance/0.96383822
85MP0000427_abnormal_hair_cycle0.96265075
86MP0000372_irregular_coat_pigmentation0.95903280
87MP0000647_abnormal_sebaceous_gland0.94906700
88MP0004510_myositis0.94730431
89MP0005171_absent_coat_pigmentation0.94434157
90MP0005409_darkened_coat_color0.94242251
91MP0008789_abnormal_olfactory_epithelium0.93625924
92MP0002909_abnormal_adrenal_gland0.93048392
93MP0002102_abnormal_ear_morphology0.91342467
94MP0004036_abnormal_muscle_relaxation0.90413684
95MP0003011_delayed_dark_adaptation0.90203430
96MP0003633_abnormal_nervous_system0.89938529
97MP0003861_abnormal_nervous_system0.89689457
98MP0000383_abnormal_hair_follicle0.88538673
99MP0004084_abnormal_cardiac_muscle0.88221203
100MP0000749_muscle_degeneration0.87601865
101MP0002653_abnormal_ependyma_morphology0.87026936
102MP0002938_white_spotting0.86888882
103MP0005620_abnormal_muscle_contractility0.86456028
104MP0002972_abnormal_cardiac_muscle0.81781755
105MP0003136_yellow_coat_color0.81712440
106MP0002234_abnormal_pharynx_morphology0.81693602
107MP0010386_abnormal_urinary_bladder0.81508799
108MP0003631_nervous_system_phenotype0.81304875
109MP0002090_abnormal_vision0.81192043
110MP0003121_genomic_imprinting0.80221716
111MP0005391_vision/eye_phenotype0.78176674
112MP0003303_peritoneal_inflammation0.77262280
113MP0003950_abnormal_plasma_membrane0.76692956
114MP0002069_abnormal_eating/drinking_beha0.76503509
115MP0004233_abnormal_muscle_weight0.76234424
116MP0002928_abnormal_bile_duct0.75143861
117MP0003632_abnormal_nervous_system0.74730606
118MP0001324_abnormal_eye_pigmentation0.73578255
119MP0008872_abnormal_physiological_respon0.71001003
120MP0003283_abnormal_digestive_organ0.70728841
121MP0002233_abnormal_nose_morphology0.70690728

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)4.23378827
2Central scotoma (HP:0000603)3.94759212
3True hermaphroditism (HP:0010459)3.90082908
4Pancreatic fibrosis (HP:0100732)3.81642890
5Pancreatic cysts (HP:0001737)3.69318056
6Congenital stationary night blindness (HP:0007642)3.68143963
7Abnormality of midbrain morphology (HP:0002418)3.66296302
8Molar tooth sign on MRI (HP:0002419)3.66296302
9Myokymia (HP:0002411)3.42768542
10Nephronophthisis (HP:0000090)3.38840674
11Febrile seizures (HP:0002373)3.35179875
12Abnormality of the corticospinal tract (HP:0002492)3.35143346
13Bony spicule pigmentary retinopathy (HP:0007737)3.32547383
14Dyschromatopsia (HP:0007641)3.29327127
15Insidious onset (HP:0003587)3.25525186
16Termporal pattern (HP:0011008)3.25525186
17Focal seizures (HP:0007359)3.24973077
18Epileptic encephalopathy (HP:0200134)3.20628903
19Abnormality of macular pigmentation (HP:0008002)3.19597550
20Degeneration of the lateral corticospinal tracts (HP:0002314)3.17816524
21Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.17816524
22Chronic hepatic failure (HP:0100626)3.14093031
23Progressive cerebellar ataxia (HP:0002073)3.05227984
24Scotoma (HP:0000575)3.02576216
25Broad-based gait (HP:0002136)3.02521018
26Hyperventilation (HP:0002883)2.89032705
27Excessive salivation (HP:0003781)2.87903172
28Drooling (HP:0002307)2.87903172
29Intestinal atresia (HP:0011100)2.87449695
30Abnormality of the renal medulla (HP:0100957)2.85239344
31Rhinitis (HP:0012384)2.81087538
32Gait imbalance (HP:0002141)2.75381926
33Pheochromocytoma (HP:0002666)2.73996590
34Polyphagia (HP:0002591)2.68490950
35Cystic liver disease (HP:0006706)2.58640338
36Abnormal ciliary motility (HP:0012262)2.58056656
37Action tremor (HP:0002345)2.57299501
38Absent rod-and cone-mediated responses on ERG (HP:0007688)2.53488862
39Ankle clonus (HP:0011448)2.53287414
40Abnormal rod and cone electroretinograms (HP:0008323)2.52096676
41Atonic seizures (HP:0010819)2.50791931
42Anencephaly (HP:0002323)2.50468529
43Limb dystonia (HP:0002451)2.48124972
44Urinary bladder sphincter dysfunction (HP:0002839)2.42589835
45Visual hallucinations (HP:0002367)2.40922068
46Abnormality of the renal cortex (HP:0011035)2.37155409
47Medial flaring of the eyebrow (HP:0010747)2.36546753
48Muscle hypertrophy of the lower extremities (HP:0008968)2.33661351
49Neuroendocrine neoplasm (HP:0100634)2.33181001
50Poor coordination (HP:0002370)2.33057955
51Truncal ataxia (HP:0002078)2.32725344
52Type II lissencephaly (HP:0007260)2.32508709
53Optic nerve hypoplasia (HP:0000609)2.31803460
54Calf muscle hypertrophy (HP:0008981)2.30121681
55Prolonged QT interval (HP:0001657)2.29331636
56Abnormal respiratory motile cilium physiology (HP:0012261)2.27386789
57Sudden death (HP:0001699)2.26315573
58Lissencephaly (HP:0001339)2.25733900
59Hypoplasia of the brainstem (HP:0002365)2.25644988
60Aplasia/Hypoplasia of the brainstem (HP:0007362)2.25644988
61Congenital primary aphakia (HP:0007707)2.24902528
62Sclerocornea (HP:0000647)2.23732245
63Absent speech (HP:0001344)2.23273570
64Congenital hepatic fibrosis (HP:0002612)2.23085791
65Attenuation of retinal blood vessels (HP:0007843)2.22917343
66Gaze-evoked nystagmus (HP:0000640)2.22260643
67Absent/shortened dynein arms (HP:0200106)2.21701190
68Dynein arm defect of respiratory motile cilia (HP:0012255)2.21701190
69Tubular atrophy (HP:0000092)2.21316817
70Genetic anticipation (HP:0003743)2.18127268
71Abnormal respiratory epithelium morphology (HP:0012253)2.18120437
72Abnormal respiratory motile cilium morphology (HP:0005938)2.18120437
73Impaired vibration sensation in the lower limbs (HP:0002166)2.17740683
74Supranuclear gaze palsy (HP:0000605)2.17405360
75Absence seizures (HP:0002121)2.17240999
76Hemiparesis (HP:0001269)2.16061950
77Syncope (HP:0001279)2.16046702
78Aplasia/Hypoplasia of the tongue (HP:0010295)2.13384693
79Urinary urgency (HP:0000012)2.11297984
80Volvulus (HP:0002580)2.09905464
81Pendular nystagmus (HP:0012043)2.09852399
82Chorioretinal atrophy (HP:0000533)2.09611637
83Spastic gait (HP:0002064)2.08660563
84Genital tract atresia (HP:0001827)2.08482511
85Pachygyria (HP:0001302)2.08146653
86Specific learning disability (HP:0001328)2.08070555
87Lower limb muscle weakness (HP:0007340)2.07789130
88Exotropia (HP:0000577)2.07679715
89Generalized tonic-clonic seizures (HP:0002069)2.07445464
90Postaxial foot polydactyly (HP:0001830)2.07422801
91Decreased central vision (HP:0007663)2.07349639
92Dialeptic seizures (HP:0011146)2.05687042
93Atrial fibrillation (HP:0005110)2.05314419
94Postaxial hand polydactyly (HP:0001162)2.03920371
95Vaginal atresia (HP:0000148)2.03212152
96Hypothermia (HP:0002045)2.02679274
97Nephrogenic diabetes insipidus (HP:0009806)2.02652967
98Epileptiform EEG discharges (HP:0011182)2.02536583
99Primary atrial arrhythmia (HP:0001692)2.02059011
100Tubulointerstitial nephritis (HP:0001970)2.01818484
101Ulnar claw (HP:0001178)2.01517704
102Tubulointerstitial abnormality (HP:0001969)2.01069080
103Amblyopia (HP:0000646)1.99386256
104Narrow forehead (HP:0000341)1.98402660
105Choroideremia (HP:0001139)1.97646703
106EEG with generalized epileptiform discharges (HP:0011198)1.96975764
107Abnormality of the calf musculature (HP:0001430)1.96333797
108Aqueductal stenosis (HP:0002410)1.95982803
109Hypsarrhythmia (HP:0002521)1.95400719
110Occipital encephalocele (HP:0002085)1.95246960
111Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.94383115
112Dysdiadochokinesis (HP:0002075)1.92893445
113Abnormal EKG (HP:0003115)1.92867635
114Abnormality of salivation (HP:0100755)1.92829382
115Agitation (HP:0000713)1.92753391
116Oligodactyly (hands) (HP:0001180)1.92519008
117Septo-optic dysplasia (HP:0100842)1.92341952
118Macroorchidism (HP:0000053)1.92253640
119Polydipsia (HP:0001959)1.91783317
120Abnormal drinking behavior (HP:0030082)1.91783317
121Protruding tongue (HP:0010808)1.89454683
122Bronchiectasis (HP:0002110)1.88722234
123Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.88577364
124Inability to walk (HP:0002540)1.88373052
125Hepatoblastoma (HP:0002884)1.87252401
126Supraventricular tachycardia (HP:0004755)1.84678695
127Poor eye contact (HP:0000817)1.84188040
128Cortical dysplasia (HP:0002539)1.83828998
129Abnormality of the labia minora (HP:0012880)1.82621783
130Gastrointestinal atresia (HP:0002589)1.82331319
131Supernumerary spleens (HP:0009799)1.82201085
132Steppage gait (HP:0003376)1.81496547
133Blue irides (HP:0000635)1.81111049
134Abolished electroretinogram (ERG) (HP:0000550)1.80811949
135Mutism (HP:0002300)1.80189933
136Inappropriate behavior (HP:0000719)1.79589600
137Scanning speech (HP:0002168)1.78474946
138Anxiety (HP:0000739)1.78247722
139Retinal dysplasia (HP:0007973)1.77164102
140Supraventricular arrhythmia (HP:0005115)1.76385920
141Cerebellar dysplasia (HP:0007033)1.76241278
142Type II diabetes mellitus (HP:0005978)1.76047860
143Tented upper lip vermilion (HP:0010804)1.75056619
144Papillary thyroid carcinoma (HP:0002895)1.74846622
145Progressive inability to walk (HP:0002505)1.74764071
146Left ventricular hypertrophy (HP:0001712)1.74290058
147Furrowed tongue (HP:0000221)1.74063169
148Male pseudohermaphroditism (HP:0000037)1.73762671
149Fetal akinesia sequence (HP:0001989)1.73534469
150Renal cortical cysts (HP:0000803)1.71200404
151Depression (HP:0000716)1.70613803
152Tubulointerstitial fibrosis (HP:0005576)1.70296600
153Aplasia/Hypoplasia of the lens (HP:0008063)1.69583683
154Keratoconus (HP:0000563)1.68044208
155Increased corneal curvature (HP:0100692)1.68044208

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.66982252
2FRK3.43830444
3CASK3.30169136
4NTRK33.12788079
5MAP3K42.89733096
6MAP2K72.70470825
7ACVR1B2.33273497
8MAPK132.21070182
9MINK12.19755690
10PHKG22.18497319
11PHKG12.18497319
12PNCK2.14276113
13EPHA32.03976897
14NTRK21.98774532
15MAP4K21.97628218
16MAP3K91.85813683
17ADRBK21.82185933
18EPHA41.80450535
19TRIM281.73237339
20STK391.60284149
21LMTK21.60254770
22KSR11.53639126
23PAK61.53339849
24TNIK1.53175312
25GRK71.53000971
26CCNB11.49778311
27MAP2K41.39751349
28BCR1.38975976
29NTRK11.36525235
30ERBB31.31023739
31SGK4941.28525017
32SGK2231.28525017
33PLK21.27823358
34STK38L1.25694905
35MUSK1.21128982
36UHMK11.20883466
37PKN11.20838231
38DAPK21.16841423
39MAPK151.15080722
40CDK51.14493105
41GRK51.14190690
42SIK31.14090865
43DYRK21.14051535
44PINK11.10864730
45OBSCN1.10406235
46WNK31.09978418
47SGK21.06812157
48CSNK1G21.05363996
49CAMK2A1.04901511
50CAMK1G1.03836934
51INSRR1.00200288
52PAK30.97636619
53WNK10.96441834
54DYRK30.93852550
55OXSR10.92792166
56DDR20.89175226
57PRKD30.89149119
58FGFR20.89120075
59DYRK1A0.87681483
60IRAK20.87301157
61MAP3K120.86609891
62PRKCG0.84407641
63PRKCE0.83769542
64CAMK2D0.81932480
65PDK40.80895276
66PDK30.80895276
67PRPF4B0.79781976
68BMPR1B0.77196524
69MKNK10.76828670
70SIK20.76753354
71CSNK1A1L0.76419105
72SGK10.75832345
73CSNK1G30.74734466
74GRK10.74002135
75CAMK2B0.70901752
76ADRBK10.70777606
77TYRO30.70678994
78WNK40.69374772
79STK110.68653500
80SGK30.67012616
81EPHB20.66476554
82YES10.65398873
83RET0.64630558
84STK240.63484261
85CAMK10.62611321
86MATK0.61755193
87ZAK0.61034581
88PDK20.60526934
89AKT30.60202870
90LATS20.58049484
91CAMKK10.57808998
92PIK3CA0.55722277
93CSNK1G10.55121002
94MKNK20.54720406
95CDK180.54395010
96KSR20.54112301
97MARK20.53034923
98PRKG10.53009066
99MAP3K60.52842981
100RPS6KA20.52176193
101CDK140.51109999
102NEK60.50835594
103IRAK10.50532423
104PRKCH0.50077256
105LIMK10.49094227
106CDC42BPA0.48877166
107PRKCZ0.47766968
108MAPK100.47710354
109CDK150.46247816
110CDK30.45946239
111RPS6KA30.45245684
112PRKACA0.43839224
113MAP3K20.43331274
114PLK40.42574300
115CAMK40.41596200
116TGFBR10.41571768
117CAMKK20.41205220
118PRKACB0.40553336
119CHUK0.39756594
120MAP3K50.39058718
121WEE10.37910548
122CSNK1D0.37076606
123STK30.36763252
124PRKAA10.34088774
125ERBB20.33185459
126CSNK1A10.29984058
127FGR0.29397630
128NUAK10.27880579
129CDK11A0.27814069
130CDK190.27735874

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047444.55369801
2Nicotine addiction_Homo sapiens_hsa050333.08669288
3Synaptic vesicle cycle_Homo sapiens_hsa047212.50957753
4Olfactory transduction_Homo sapiens_hsa047402.49304271
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.44341393
6Circadian entrainment_Homo sapiens_hsa047132.36822722
7Glutamatergic synapse_Homo sapiens_hsa047242.34167249
8GABAergic synapse_Homo sapiens_hsa047272.27623039
9Morphine addiction_Homo sapiens_hsa050322.23784081
10Dopaminergic synapse_Homo sapiens_hsa047282.08749618
11Taste transduction_Homo sapiens_hsa047421.97921829
12Long-term potentiation_Homo sapiens_hsa047201.94016069
13Serotonergic synapse_Homo sapiens_hsa047261.92686271
14Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.92298097
15Amphetamine addiction_Homo sapiens_hsa050311.91528313
16Steroid biosynthesis_Homo sapiens_hsa001001.85110341
17Insulin secretion_Homo sapiens_hsa049111.84304253
18Cholinergic synapse_Homo sapiens_hsa047251.80543619
19Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.76722136
20Maturity onset diabetes of the young_Homo sapiens_hsa049501.74849122
21Butanoate metabolism_Homo sapiens_hsa006501.73270963
22Protein export_Homo sapiens_hsa030601.69934333
23Axon guidance_Homo sapiens_hsa043601.67060577
24Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.66318218
25Salivary secretion_Homo sapiens_hsa049701.62988620
26Renin secretion_Homo sapiens_hsa049241.62590492
27Cardiac muscle contraction_Homo sapiens_hsa042601.62588870
28Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.60828587
29Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.55631160
30Cocaine addiction_Homo sapiens_hsa050301.48197590
31Calcium signaling pathway_Homo sapiens_hsa040201.45511274
32Gastric acid secretion_Homo sapiens_hsa049711.43893025
33Long-term depression_Homo sapiens_hsa047301.43369382
34Oxytocin signaling pathway_Homo sapiens_hsa049211.40153938
35Tryptophan metabolism_Homo sapiens_hsa003801.36202620
36Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.31481987
37Dilated cardiomyopathy_Homo sapiens_hsa054141.30562103
38Aldosterone synthesis and secretion_Homo sapiens_hsa049251.29863770
39GnRH signaling pathway_Homo sapiens_hsa049121.20116161
40Gap junction_Homo sapiens_hsa045401.18960938
41Nitrogen metabolism_Homo sapiens_hsa009101.18599458
42Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.13332084
43cAMP signaling pathway_Homo sapiens_hsa040241.12979311
44Type II diabetes mellitus_Homo sapiens_hsa049301.11729851
45cGMP-PKG signaling pathway_Homo sapiens_hsa040221.11327833
46Collecting duct acid secretion_Homo sapiens_hsa049661.09805148
47Dorso-ventral axis formation_Homo sapiens_hsa043201.09512017
48Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.08941852
49Phosphatidylinositol signaling system_Homo sapiens_hsa040701.08686541
50Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.08401856
51Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.07306661
52Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.06941786
53ErbB signaling pathway_Homo sapiens_hsa040120.99833818
54Melanogenesis_Homo sapiens_hsa049160.98911399
55Rheumatoid arthritis_Homo sapiens_hsa053230.95923921
56ABC transporters_Homo sapiens_hsa020100.94080914
57Oxidative phosphorylation_Homo sapiens_hsa001900.92227254
58Alzheimers disease_Homo sapiens_hsa050100.91884144
59Estrogen signaling pathway_Homo sapiens_hsa049150.90837133
60Vascular smooth muscle contraction_Homo sapiens_hsa042700.90477108
61Fatty acid biosynthesis_Homo sapiens_hsa000610.90130104
62African trypanosomiasis_Homo sapiens_hsa051430.86293248
63Vibrio cholerae infection_Homo sapiens_hsa051100.83521516
64Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.83289217
65Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.82420848
66NOD-like receptor signaling pathway_Homo sapiens_hsa046210.80932899
67Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.80914710
68Parkinsons disease_Homo sapiens_hsa050120.80379190
69Alcoholism_Homo sapiens_hsa050340.78412251
70Wnt signaling pathway_Homo sapiens_hsa043100.77397486
71Oocyte meiosis_Homo sapiens_hsa041140.76908866
72Glioma_Homo sapiens_hsa052140.76308926
73Circadian rhythm_Homo sapiens_hsa047100.75190127
74Huntingtons disease_Homo sapiens_hsa050160.73368933
75Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.73112764
76alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.71663721
77Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.71433656
78Linoleic acid metabolism_Homo sapiens_hsa005910.70407288
79Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.69096696
80Choline metabolism in cancer_Homo sapiens_hsa052310.68930547
81Ovarian steroidogenesis_Homo sapiens_hsa049130.68440288
82Primary bile acid biosynthesis_Homo sapiens_hsa001200.68320886
83Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.68282040
84Propanoate metabolism_Homo sapiens_hsa006400.68187564
85MAPK signaling pathway_Homo sapiens_hsa040100.67982528
86Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.65093756
87Ras signaling pathway_Homo sapiens_hsa040140.65013042
88Fanconi anemia pathway_Homo sapiens_hsa034600.63094317
89Endometrial cancer_Homo sapiens_hsa052130.62581986
90Hedgehog signaling pathway_Homo sapiens_hsa043400.62247365
91Thyroid hormone signaling pathway_Homo sapiens_hsa049190.62022717
92Glucagon signaling pathway_Homo sapiens_hsa049220.61010334
93Pancreatic secretion_Homo sapiens_hsa049720.60103650
94Peroxisome_Homo sapiens_hsa041460.59619178
95Phospholipase D signaling pathway_Homo sapiens_hsa040720.59132906
96Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.58618669
97Intestinal immune network for IgA production_Homo sapiens_hsa046720.57189372
98Renal cell carcinoma_Homo sapiens_hsa052110.57004287
99Insulin signaling pathway_Homo sapiens_hsa049100.56078936
100Inositol phosphate metabolism_Homo sapiens_hsa005620.55956699
101Toll-like receptor signaling pathway_Homo sapiens_hsa046200.54352006
102Basal transcription factors_Homo sapiens_hsa030220.52380468
103Ether lipid metabolism_Homo sapiens_hsa005650.52154087
104Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.51974031
105Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.51948142
106Thyroid hormone synthesis_Homo sapiens_hsa049180.51667613
107TNF signaling pathway_Homo sapiens_hsa046680.51106200
108Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.51067404
109Tight junction_Homo sapiens_hsa045300.50298875
110Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.50250178
111SNARE interactions in vesicular transport_Homo sapiens_hsa041300.50112561
112Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.48961092
113Basal cell carcinoma_Homo sapiens_hsa052170.48151692
114Hippo signaling pathway_Homo sapiens_hsa043900.47398352
115Colorectal cancer_Homo sapiens_hsa052100.47171215
116RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.46521790
117Sphingolipid signaling pathway_Homo sapiens_hsa040710.46188652
118Regulation of autophagy_Homo sapiens_hsa041400.44402084
119Rap1 signaling pathway_Homo sapiens_hsa040150.43938177
120Neurotrophin signaling pathway_Homo sapiens_hsa047220.43770189
121Prolactin signaling pathway_Homo sapiens_hsa049170.42746239
122Sphingolipid metabolism_Homo sapiens_hsa006000.41336621
123Longevity regulating pathway - mammal_Homo sapiens_hsa042110.41108578
124Melanoma_Homo sapiens_hsa052180.39612638
125Pertussis_Homo sapiens_hsa051330.39225913
126Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.39146053
127Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.38564793
128TGF-beta signaling pathway_Homo sapiens_hsa043500.37792006
129Selenocompound metabolism_Homo sapiens_hsa004500.36668133
130Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.36252362
131Asthma_Homo sapiens_hsa053100.35882877
132Carbohydrate digestion and absorption_Homo sapiens_hsa049730.35156275
133Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.34786335
134mTOR signaling pathway_Homo sapiens_hsa041500.32978368
135Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.30590080
136Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.30114261
137Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.29704946

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