FSTL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a protein with similarity to follistatin, an activin-binding protein. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. This gene product is thought to be an autoantigen associated with rheumatoid arthritis. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1extracellular fibril organization (GO:0043206)7.75377482
2protein heterotrimerization (GO:0070208)7.46408182
3collagen fibril organization (GO:0030199)6.89304667
4fibril organization (GO:0097435)6.62938210
5sequestering of extracellular ligand from receptor (GO:0035581)5.87541136
6dermatan sulfate biosynthetic process (GO:0030208)5.87439116
7peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)5.64535150
8metanephric mesenchyme development (GO:0072075)5.46567531
9dermatan sulfate metabolic process (GO:0030205)5.44658408
10chondrocyte proliferation (GO:0035988)5.11255579
11kidney mesenchyme development (GO:0072074)5.03262754
12bone trabecula formation (GO:0060346)4.83816309
13positive regulation of osteoblast proliferation (GO:0033690)4.65343229
14regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)4.51007235
15negative regulation of cardiac muscle cell apoptotic process (GO:0010667)4.47792532
16cell migration involved in heart development (GO:0060973)4.39124566
17keratan sulfate catabolic process (GO:0042340)4.28183214
18collagen metabolic process (GO:0032963)4.12561296
19type B pancreatic cell proliferation (GO:0044342)4.01699073
20wound healing, spreading of epidermal cells (GO:0035313)3.99138079
21collagen catabolic process (GO:0030574)3.95486549
22multicellular organismal macromolecule metabolic process (GO:0044259)3.82098750
23protein retention in ER lumen (GO:0006621)3.78535554
24paraxial mesoderm development (GO:0048339)3.77435581
25cell migration involved in sprouting angiogenesis (GO:0002042)3.71441751
26regulation of cardiac muscle cell apoptotic process (GO:0010665)3.67160012
27multicellular organismal metabolic process (GO:0044236)3.63044856
28negative regulation of striated muscle cell apoptotic process (GO:0010664)3.60997660
29maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.60855231
30vascular endothelial growth factor signaling pathway (GO:0038084)3.60272635
31multicellular organismal catabolic process (GO:0044243)3.59657653
32negative regulation of smooth muscle cell migration (GO:0014912)3.55838313
33craniofacial suture morphogenesis (GO:0097094)3.54039529
34negative regulation of complement activation (GO:0045916)3.53295182
35extracellular regulation of signal transduction (GO:1900115)3.50768729
36extracellular negative regulation of signal transduction (GO:1900116)3.50768729
37peripheral nervous system neuron development (GO:0048935)3.48041557
38regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.47610623
39glomerular basement membrane development (GO:0032836)3.46397701
40regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.44402393
41regulation of striated muscle cell apoptotic process (GO:0010662)3.43218990
42lymph vessel development (GO:0001945)3.41318208
43extracellular matrix disassembly (GO:0022617)3.39176751
44substrate adhesion-dependent cell spreading (GO:0034446)3.35535816
45cellular response to ATP (GO:0071318)3.35056358
46chondroitin sulfate biosynthetic process (GO:0030206)3.34180310
47substrate-dependent cell migration (GO:0006929)3.32443023
48positive regulation of endothelial cell apoptotic process (GO:2000353)3.29888965
49endodermal cell differentiation (GO:0035987)3.28903200
50axon extension involved in axon guidance (GO:0048846)3.24155679
51neuron projection extension involved in neuron projection guidance (GO:1902284)3.24155679
52cellular response to vitamin (GO:0071295)3.23390725
53cell-substrate junction assembly (GO:0007044)3.22518057
54extracellular matrix organization (GO:0030198)3.22157116
55extracellular structure organization (GO:0043062)3.20785867
56wound healing, spreading of cells (GO:0044319)3.20169042
57myoblast migration (GO:0051451)3.19262645
58endocardial cushion morphogenesis (GO:0003203)3.17395181
59heparan sulfate proteoglycan biosynthetic process (GO:0015012)3.17063260
60negative regulation of fatty acid transport (GO:2000192)3.16756128
61extracellular matrix assembly (GO:0085029)3.14083418
62smooth muscle tissue development (GO:0048745)3.12431767
63endothelial cell proliferation (GO:0001935)3.09036762
64artery development (GO:0060840)3.08652847
65negative regulation of cartilage development (GO:0061037)3.07846048
66mesenchyme morphogenesis (GO:0072132)3.06756768
67cranial suture morphogenesis (GO:0060363)3.05280111
68skin morphogenesis (GO:0043589)3.04605461
69COPI coating of Golgi vesicle (GO:0048205)3.04085134
70Golgi transport vesicle coating (GO:0048200)3.04085134
71regulation of branching involved in salivary gland morphogenesis (GO:0060693)3.03184427
72endocardial cushion development (GO:0003197)3.01535999
73Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.99742361
74protein targeting to plasma membrane (GO:0072661)2.96628909
75opsonization (GO:0008228)2.96254307
76camera-type eye morphogenesis (GO:0048593)2.96014717
77glomerulus development (GO:0032835)2.95540302
78outer ear morphogenesis (GO:0042473)2.95512124
79stress fiber assembly (GO:0043149)2.94719530
80negative regulation of embryonic development (GO:0045992)2.93808055
81protein localization to cell surface (GO:0034394)2.93713734
82cell proliferation involved in kidney development (GO:0072111)2.89605559
83regulation of establishment of planar polarity (GO:0090175)2.88959717
84negative regulation of BMP signaling pathway (GO:0030514)2.88943066
85establishment of planar polarity (GO:0001736)2.88438919
86establishment of tissue polarity (GO:0007164)2.88438919
87adherens junction assembly (GO:0034333)2.88086564
88negative regulation of axon extension involved in axon guidance (GO:0048843)2.87086140
89cochlea morphogenesis (GO:0090103)2.86826092
90basement membrane organization (GO:0071711)2.86726916
91cell adhesion mediated by integrin (GO:0033627)2.86065126
92negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.85169889
93adhesion of symbiont to host cell (GO:0044650)2.84840313
94virion attachment to host cell (GO:0019062)2.84840313
95lymphangiogenesis (GO:0001946)2.84633859
96cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.84260537
97regulation of macrophage cytokine production (GO:0010935)2.83978596
98chondrocyte development (GO:0002063)2.83746426
99peptidyl-proline hydroxylation (GO:0019511)2.81290284
100sprouting angiogenesis (GO:0002040)2.79352576
101cellular response to vitamin D (GO:0071305)2.78781346
102regulation of cartilage development (GO:0061035)2.78653301
103muscle cell migration (GO:0014812)2.78330822
104tooth mineralization (GO:0034505)2.78285526
105cardiac epithelial to mesenchymal transition (GO:0060317)2.77586764
106venous blood vessel morphogenesis (GO:0048845)2.77580878
107retina vasculature morphogenesis in camera-type eye (GO:0061299)2.77503282
108chondroitin sulfate catabolic process (GO:0030207)2.77451631
109positive regulation of glycogen biosynthetic process (GO:0045725)2.77407287
110mesenchymal-epithelial cell signaling (GO:0060638)2.76822836
111regulation of plasminogen activation (GO:0010755)2.76632817
112regulation of chondrocyte differentiation (GO:0032330)2.74787206
113pericardium development (GO:0060039)2.74765631
114positive regulation of epithelial to mesenchymal transition (GO:0010718)2.73903234
115hippo signaling (GO:0035329)2.73715686
116negative regulation of chondrocyte differentiation (GO:0032331)2.73596766
117endothelial cell morphogenesis (GO:0001886)2.73568135
118neural crest cell development (GO:0014032)2.73311006
119apoptotic cell clearance (GO:0043277)2.72513687
120regulation of cardiac muscle hypertrophy (GO:0010611)2.71975681
121cell-substrate adherens junction assembly (GO:0007045)2.70588677
122focal adhesion assembly (GO:0048041)2.70588677
123positive regulation of myoblast differentiation (GO:0045663)2.69752825
124embryonic cranial skeleton morphogenesis (GO:0048701)2.69655435
125negative regulation of protein activation cascade (GO:2000258)2.68993355
126prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060522.68651961
127barbed-end actin filament capping (GO:0051016)2.68558697
128positive regulation of blood vessel endothelial cell migration (GO:0043536)2.68205034
129positive regulation of cartilage development (GO:0061036)2.67953120
130regulation of osteoblast proliferation (GO:0033688)2.67392142
131heparan sulfate proteoglycan metabolic process (GO:0030201)2.67377606
132regulation of integrin-mediated signaling pathway (GO:2001044)2.67158992
133plasma membrane repair (GO:0001778)2.66941181
134blood vessel endothelial cell migration (GO:0043534)2.66327647
135mesenchyme development (GO:0060485)2.65976850
136branching involved in prostate gland morphogenesis (GO:0060442)2.64710749
137planar cell polarity pathway involved in neural tube closure (GO:0090179)2.63366617
138mammary gland development (GO:0030879)2.62988455
139trabecula formation (GO:0060343)2.62497680
140regulation of muscle hypertrophy (GO:0014743)2.60101135
141positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.58760627
142regulation of SMAD protein import into nucleus (GO:0060390)2.58642571
143negative regulation of dendrite morphogenesis (GO:0050774)2.58599137
144regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.58347454
145regulation of transforming growth factor beta2 production (GO:0032909)2.57980922
146mesenchymal cell development (GO:0014031)2.57445050
147blood vessel maturation (GO:0001955)2.56462063
148nucleotide-sugar biosynthetic process (GO:0009226)2.55874011

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human6.17593662
2RBPJ_22232070_ChIP-Seq_NCS_Mouse5.51479744
3* RARG_19884340_ChIP-ChIP_MEFs_Mouse4.15550720
4PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse3.54233472
5* CJUN_26792858_Chip-Seq_BT549_Human2.90564729
6* ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.86888298
7* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse2.71815710
8* WT1_19549856_ChIP-ChIP_CCG9911_Human2.64291231
9* EP300_21415370_ChIP-Seq_HL-1_Mouse2.60399869
10CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.52699764
11TP63_17297297_ChIP-ChIP_HaCaT_Human2.45361235
12SMAD_19615063_ChIP-ChIP_OVARY_Human2.42639104
13NRF2_20460467_ChIP-Seq_MEFs_Mouse2.38200006
14NFE2L2_20460467_ChIP-Seq_MEFs_Mouse2.38200006
15CDX2_19796622_ChIP-Seq_MESCs_Mouse2.21393724
16TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.19453689
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.11788963
18CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse2.10006962
19TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.07081477
20SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.03213340
21NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.00926565
22HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse2.00788615
23TP53_18474530_ChIP-ChIP_U2OS_Human1.95852721
24CLOCK_20551151_ChIP-Seq_293T_Human1.95338120
25SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.94683938
26BRD4_25478319_ChIP-Seq_HGPS_Human1.93534759
27RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.87462992
28FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.83457399
29STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.79347360
30SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.78451532
31ESR1_20079471_ChIP-ChIP_T-47D_Human1.78385095
32ESR1_21235772_ChIP-Seq_MCF-7_Human1.77957246
33EZH2_18974828_ChIP-Seq_MESCs_Mouse1.76926232
34RNF2_18974828_ChIP-Seq_MESCs_Mouse1.76926232
35EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.74715594
36PIAS1_25552417_ChIP-Seq_VCAP_Human1.71741461
37GBX2_23144817_ChIP-Seq_PC3_Human1.68307161
38SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.67797096
39WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.62614210
40SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.62188571
41ZNF217_24962896_ChIP-Seq_MCF-7_Human1.60022078
42PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.56139768
43SOX2_20726797_ChIP-Seq_SW620_Human1.55498593
44* TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.54554140
45ELK3_25401928_ChIP-Seq_HUVEC_Human1.51825996
46SALL4_18804426_ChIP-ChIP_XEN_Mouse1.51293218
47SOX9_24532713_ChIP-Seq_HFSC_Mouse1.50067929
48P300_27058665_Chip-Seq_ZR-75-30cells_Human1.47752975
49ESR2_21235772_ChIP-Seq_MCF-7_Human1.46487878
50JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.44900525
51POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.43819642
52PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.43683887
53SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.42644325
54TP53_20018659_ChIP-ChIP_R1E_Mouse1.40677980
55HIF1A_21447827_ChIP-Seq_MCF-7_Human1.38823749
56SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.37491106
57SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.37491106
58AR_21572438_ChIP-Seq_LNCaP_Human1.37107219
59JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.36650204
60SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.36074812
61SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.34667694
62NFIB_24661679_ChIP-Seq_LUNG_Mouse1.34389653
63ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.33795709
64RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.33057813
65JARID2_20075857_ChIP-Seq_MESCs_Mouse1.32036771
66MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.31602521
67TBX20_22080862_ChIP-Seq_HEART_Mouse1.28597991
68TBX20_22328084_ChIP-Seq_HEART_Mouse1.28597991
69EZH2_27304074_Chip-Seq_ESCs_Mouse1.27671100
70* PPAR_26484153_Chip-Seq_NCI-H1993_Human1.27164273
71BCAT_22108803_ChIP-Seq_LS180_Human1.26526450
72TP53_22127205_ChIP-Seq_IMR90_Human1.25491084
73GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.24619740
74BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.24032975
75ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.22373060
76SMC3_22415368_ChIP-Seq_MEFs_Mouse1.20670763
77AHR_22903824_ChIP-Seq_MCF-7_Human1.17650277
78KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.17296999
79AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.16823616
80TP53_23651856_ChIP-Seq_MEFs_Mouse1.15827150
81DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.15104008
82P300_19829295_ChIP-Seq_ESCs_Human1.13085353
83RNF2_27304074_Chip-Seq_ESCs_Mouse1.12877738
84MTF2_20144788_ChIP-Seq_MESCs_Mouse1.12806800
85ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.12312483
86* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.12020407
87* GATA2_21666600_ChIP-Seq_HMVEC_Human1.10669664
88* SMC1_22415368_ChIP-Seq_MEFs_Mouse1.10560811
89JUN_21703547_ChIP-Seq_K562_Human1.10383177
90* SMAD4_21799915_ChIP-Seq_A2780_Human1.09048689
91* SA1_22415368_ChIP-Seq_MEFs_Mouse1.06527686
92* NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.06301744
93OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.05987737
94THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.04593257
95* PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.04276112
96TP63_23658742_ChIP-Seq_EP156T_Human1.03887397
97WT1_25993318_ChIP-Seq_PODOCYTE_Human1.03135842
98SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.03011550
99TCF4_18268006_ChIP-ChIP_LS174T_Human1.02005878
100TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.01487488
101TCF3_18692474_ChIP-Seq_MEFs_Mouse0.99813039
102SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.97923245
103ISL1_27105846_Chip-Seq_CPCs_Mouse0.97673237
104JARID2_20064375_ChIP-Seq_MESCs_Mouse0.97361111
105BMI1_23680149_ChIP-Seq_NPCS_Mouse0.97208741
106ARNT_22903824_ChIP-Seq_MCF-7_Human0.97142403
107* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.96942910
108TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.95741651
109TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.94185280
110TBX3_20139965_ChIP-Seq_ESCs_Mouse0.94130485
111TP53_16413492_ChIP-PET_HCT116_Human0.94043046
112TBX3_20139965_ChIP-Seq_MESCs_Mouse0.93911929
113UBF1/2_26484160_Chip-Seq_HMECs_Human0.92971483
114EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.92844093
115CTBP2_25329375_ChIP-Seq_LNCAP_Human0.92177484
116ZFP281_18757296_ChIP-ChIP_E14_Mouse0.91867268
117ZFP281_27345836_Chip-Seq_ESCs_Mouse0.91830391
118NFI_21473784_ChIP-Seq_ESCs_Mouse0.91790732
119* PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.90851804
120POU3F2_20337985_ChIP-ChIP_501MEL_Human0.90223767
121YAP1_20516196_ChIP-Seq_MESCs_Mouse0.89272161
122RING1B_27294783_Chip-Seq_ESCs_Mouse0.88076056
123PPARD_21283829_ChIP-Seq_MYOFIBROBLAST_Human0.87128412
124CTNNB1_20460455_ChIP-Seq_HCT116_Human0.87119491
125* NR3C1_23031785_ChIP-Seq_PC12_Mouse0.86000709
126RXR_22108803_ChIP-Seq_LS180_Human0.85216667
127ZFP57_27257070_Chip-Seq_ESCs_Mouse0.83379125
128SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.83059795
129NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.82686463

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen9.06460108
2MP0005503_abnormal_tendon_morphology7.46458264
3MP0005275_abnormal_skin_tensile6.19536339
4MP0003279_aneurysm3.54328736
5MP0001958_emphysema3.29924438
6MP0003705_abnormal_hypodermis_morpholog3.25364319
7MP0004272_abnormal_basement_membrane2.82739760
8MP0010368_abnormal_lymphatic_system2.61177604
9MP0005508_abnormal_skeleton_morphology2.40397029
10MP0006054_spinal_hemorrhage2.36791438
11MP0009384_cardiac_valve_regurgitation2.24606615
12MP0002060_abnormal_skin_morphology2.23171202
13MP0002108_abnormal_muscle_morphology2.20158458
14MP0001542_abnormal_bone_strength2.17153672
15MP0010030_abnormal_orbit_morphology2.05974426
16MP0009250_abnormal_appendicular_skeleto2.00542088
17MP0003385_abnormal_body_wall1.66989064
18MP0003566_abnormal_cell_adhesion1.66572788
19MP0003941_abnormal_skin_development1.66106868
20MP0005171_absent_coat_pigmentation1.60399166
21MP0003950_abnormal_plasma_membrane1.57255928
22MP0002282_abnormal_trachea_morphology1.55600223
23MP0002295_abnormal_pulmonary_circulatio1.54931969
24MP0001243_abnormal_dermal_layer1.52989382
25MP0004134_abnormal_chest_morphology1.48534300
26MP0005023_abnormal_wound_healing1.47415351
27MP0000013_abnormal_adipose_tissue1.47390292
28MP0005623_abnormal_meninges_morphology1.46351788
29MP0004858_abnormal_nervous_system1.43646627
30MP0003942_abnormal_urinary_system1.42991850
31MP0001879_abnormal_lymphatic_vessel1.40562798
32MP0001299_abnormal_eye_distance/1.29920991
33MP0009053_abnormal_anal_canal1.28393286
34MP0009780_abnormal_chondrocyte_physiolo1.25904691
35MP0005390_skeleton_phenotype1.24524462
36MP0000534_abnormal_ureter_morphology1.23519748
37MP0000749_muscle_degeneration1.22340337
38MP0003115_abnormal_respiratory_system1.21595551
39MP0000767_abnormal_smooth_muscle1.10016233
40MP0005257_abnormal_intraocular_pressure1.09320853
41MP0002115_abnormal_skeleton_extremities1.08840490
42MP0002932_abnormal_joint_morphology1.07010368
43MP0002735_abnormal_chemical_nociception1.05629332
44MP0000163_abnormal_cartilage_morphology1.03544086
45MP0002249_abnormal_larynx_morphology1.01987338
46MP0002896_abnormal_bone_mineralization1.01830967
47MP0008775_abnormal_heart_ventricle1.01360920
48MP0003122_maternal_imprinting1.00314891
49MP0001986_abnormal_taste_sensitivity0.99470226
50MP0004883_abnormal_blood_vessel0.96660187
51MP0005595_abnormal_vascular_smooth0.96368649
52MP0002933_joint_inflammation0.94213178
53MP0002113_abnormal_skeleton_development0.93443227
54MP0001177_atelectasis0.92317231
55MP0005367_renal/urinary_system_phenotyp0.91080228
56MP0000516_abnormal_urinary_system0.91080228
57MP0000049_abnormal_middle_ear0.91029612
58MP0005197_abnormal_uvea_morphology0.90921209
59MP0001849_ear_inflammation0.90280381
60MP0003091_abnormal_cell_migration0.89689911
61MP0000462_abnormal_digestive_system0.88432859
62MP0005388_respiratory_system_phenotype0.87981544
63MP0002133_abnormal_respiratory_system0.87981544
64MP0000751_myopathy0.87505099
65MP0002938_white_spotting0.85036242
66MP0000537_abnormal_urethra_morphology0.84619219
67MP0001915_intracranial_hemorrhage0.84062775
68MP0000759_abnormal_skeletal_muscle0.83635562
69MP0000428_abnormal_craniofacial_morphol0.82476052
70MP0002009_preneoplasia0.81912645
71MP0000003_abnormal_adipose_tissue0.81416442
72MP0002109_abnormal_limb_morphology0.80752673
73MP0002998_abnormal_bone_remodeling0.79715907
74MP0003755_abnormal_palate_morphology0.78385183
75MP0001175_abnormal_lung_morphology0.78257010
76MP0002128_abnormal_blood_circulation0.75042104
77MP0002877_abnormal_melanocyte_morpholog0.73300111
78MP0002972_abnormal_cardiac_muscle0.73112865
79MP0002168_other_aberrant_phenotype0.72005402
80MP0010352_gastrointestinal_tract_polyps0.71927235
81MP0002697_abnormal_eye_size0.71871074
82MP0000733_abnormal_muscle_development0.69302949
83MP0002254_reproductive_system_inflammat0.67047785
84MP0005369_muscle_phenotype0.66869453
85MP0003448_altered_tumor_morphology0.66522709
86MP0010771_integument_phenotype0.66448812
87MP0003935_abnormal_craniofacial_develop0.65935485
88MP0003795_abnormal_bone_structure0.65209277
89MP0003283_abnormal_digestive_organ0.64913645
90MP0006138_congestive_heart_failure0.63126160
91MP0000432_abnormal_head_morphology0.62913533
92MP0004084_abnormal_cardiac_muscle0.62568382
93MP0002116_abnormal_craniofacial_bone0.62420897
94MP0005164_abnormal_response_to0.61680955
95MP0000750_abnormal_muscle_regeneration0.61548519
96MP0005620_abnormal_muscle_contractility0.61246158
97MP0004087_abnormal_muscle_fiber0.60745156
98MP0002092_abnormal_eye_morphology0.60661962
99MP0001348_abnormal_lacrimal_gland0.60592370
100MP0000762_abnormal_tongue_morphology0.59407744
101MP0002114_abnormal_axial_skeleton0.58674891
102MP0003937_abnormal_limbs/digits/tail_de0.58477912
103MP0010386_abnormal_urinary_bladder0.58426388
104MP0000343_altered_response_to0.57957433
105MP0001614_abnormal_blood_vessel0.57845064
106MP0000467_abnormal_esophagus_morphology0.56002020
107MP0004233_abnormal_muscle_weight0.55308553
108MP0002233_abnormal_nose_morphology0.55186316
109MP0003567_abnormal_fetal_cardiomyocyte0.55007423
110MP0004484_altered_response_of0.55003779
111MP0001661_extended_life_span0.54589858
112MP0003300_gastrointestinal_ulcer0.54386360
113MP0001968_abnormal_touch/_nociception0.53983939
114MP0005193_abnormal_anterior_eye0.53799958
115MP0002837_dystrophic_cardiac_calcinosis0.53135819
116MP0002177_abnormal_outer_ear0.51949430
117MP0002925_abnormal_cardiovascular_devel0.51829241
118MP0006276_abnormal_autonomic_nervous0.51491392
119MP0009697_abnormal_copulation0.50975236
120MP0004036_abnormal_muscle_relaxation0.49665140
121MP0000266_abnormal_heart_morphology0.49257570

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)8.16379029
2Premature rupture of membranes (HP:0001788)7.14607499
3Abnormality of dentin (HP:0010299)4.51282573
4Soft skin (HP:0000977)4.50473940
5Aortic dissection (HP:0002647)4.47935791
6Broad metatarsal (HP:0001783)4.46601154
7Aortic aneurysm (HP:0004942)4.20184664
8Atrophic scars (HP:0001075)3.95438876
9Shallow orbits (HP:0000586)3.94567879
10Vertebral compression fractures (HP:0002953)3.91230192
11Bladder diverticulum (HP:0000015)3.80549718
12Fragile skin (HP:0001030)3.79551739
13Biconcave vertebral bodies (HP:0004586)3.78253345
14Wormian bones (HP:0002645)3.66746674
15Dilatation of the ascending aorta (HP:0005111)3.65826422
16Ankle contracture (HP:0006466)3.53097714
17Spinal rigidity (HP:0003306)3.27065535
18Cervical subluxation (HP:0003308)3.25981259
19Blue sclerae (HP:0000592)3.25336708
20Vascular tortuosity (HP:0004948)3.20250205
21Neonatal short-limb short stature (HP:0008921)3.18299229
22Short nail (HP:0001799)3.16616633
23Follicular hyperkeratosis (HP:0007502)3.14553439
24Cerebral aneurysm (HP:0004944)3.11247972
25Overgrowth (HP:0001548)2.92374339
26Increased connective tissue (HP:0009025)2.90181531
27Asymmetry of the thorax (HP:0001555)2.82138138
28Camptodactyly of toe (HP:0001836)2.79996844
29Spondylolisthesis (HP:0003302)2.77798318
30Hyperextensible skin (HP:0000974)2.75450991
31Mitral valve prolapse (HP:0001634)2.74960523
32Wrist flexion contracture (HP:0001239)2.74891213
33Subacute progressive viral hepatitis (HP:0006572)2.70823711
34Peritonitis (HP:0002586)2.69257592
35Morphological abnormality of the middle ear (HP:0008609)2.68128443
36Genu recurvatum (HP:0002816)2.66183774
37Increased variability in muscle fiber diameter (HP:0003557)2.65841109
38Mitral regurgitation (HP:0001653)2.62029301
39Syringomyelia (HP:0003396)2.61018346
40Spinal cord lesions (HP:0100561)2.61018346
41Abnormal delivery (HP:0001787)2.60827012
42Thin bony cortex (HP:0002753)2.57139627
43Type 1 muscle fiber predominance (HP:0003803)2.52732879
44Alopecia of scalp (HP:0002293)2.51757127
45Knee flexion contracture (HP:0006380)2.51663840
46Wide anterior fontanel (HP:0000260)2.49268556
47Ulnar bowing (HP:0003031)2.44685191
48Joint laxity (HP:0001388)2.42891206
49Bowel diverticulosis (HP:0005222)2.42690891
50Pulmonary artery stenosis (HP:0004415)2.39511430
51Osteolytic defects of the hand bones (HP:0009699)2.32829577
52Osteolytic defects of the phalanges of the hand (HP:0009771)2.32829577
53Elbow flexion contracture (HP:0002987)2.29450295
54Disproportionate tall stature (HP:0001519)2.25545818
55Abnormality of skeletal muscle fiber size (HP:0012084)2.21776582
56Broad long bones (HP:0005622)2.17805254
57Infantile muscular hypotonia (HP:0008947)2.17406792
58Arterial tortuosity (HP:0005116)2.15197790
59Breech presentation (HP:0001623)2.15168790
60Hypoventilation (HP:0002791)2.14969546
61Beaking of vertebral bodies (HP:0004568)2.13569522
62Abnormality of the ischium (HP:0003174)2.12959073
63Bell-shaped thorax (HP:0001591)2.11772980
64Broad ribs (HP:0000885)2.10833834
65Joint contractures involving the joints of the feet (HP:0100492)2.10238219
66Flexion contracture of toe (HP:0005830)2.10238219
67Hypoplasia of the iris (HP:0007676)2.10220381
68Abnormality of the acetabulum (HP:0003170)2.10201170
69Bradycardia (HP:0001662)2.09676202
70Absent frontal sinuses (HP:0002688)2.09489349
71Distal lower limb muscle weakness (HP:0009053)2.05623681
72Mildly elevated creatine phosphokinase (HP:0008180)2.02469366
73Narrow nasal bridge (HP:0000446)2.00874232
74Deviation of the hallux (HP:0010051)2.00447132
75Ulnar claw (HP:0001178)1.99566917
76Delayed cranial suture closure (HP:0000270)1.98872446
77Striae distensae (HP:0001065)1.98674565
78Hallux valgus (HP:0001822)1.93416811
79Delayed closure of the anterior fontanelle (HP:0001476)1.92050654
80Renal duplication (HP:0000075)1.91615106
81Osteopenia (HP:0000938)1.90066335
82Myotonia (HP:0002486)1.88602117
83Ectopia lentis (HP:0001083)1.87160167
84Round ear (HP:0100830)1.86802077
85Osteoarthritis (HP:0002758)1.86744532
86Nonimmune hydrops fetalis (HP:0001790)1.86131605
87Aortic valve stenosis (HP:0001650)1.85374918
88Flat cornea (HP:0007720)1.84308187
89Deformed tarsal bones (HP:0008119)1.81929010
90Protruding ear (HP:0000411)1.81097685
91Coronal craniosynostosis (HP:0004440)1.81009448
92Mesomelia (HP:0003027)1.80802274
93Abnormality of the anterior chamber (HP:0000593)1.80427983
94Mild short stature (HP:0003502)1.80386407
95Broad phalanx (HP:0006009)1.79410131
96Decreased skull ossification (HP:0004331)1.79098915
97Calcaneovalgus deformity (HP:0001848)1.78877910
98Aneurysm (HP:0002617)1.78804369
99Distal lower limb amyotrophy (HP:0008944)1.78303061
100Limited hip movement (HP:0008800)1.77564264
101Patent foramen ovale (HP:0001655)1.76141383
102Inguinal hernia (HP:0000023)1.75759536
103Short hallux (HP:0010109)1.75230821
104Abnormality of skull ossification (HP:0002703)1.75141521
105Limb-girdle muscle weakness (HP:0003325)1.74381667
106Slender build (HP:0001533)1.73432893
107Aortic regurgitation (HP:0001659)1.73171712
108Cardiovascular calcification (HP:0011915)1.72925107
109Neoplasm of head and neck (HP:0012288)1.72702365
110Esophageal neoplasm (HP:0100751)1.72702365
111Joint stiffness (HP:0001387)1.72431820
112Venous insufficiency (HP:0005293)1.71755501
113Arachnodactyly (HP:0001166)1.71726841
114Tarsal synostosis (HP:0008368)1.70982423
115Mitral stenosis (HP:0001718)1.70531721
116Venous abnormality (HP:0002624)1.69424231
117Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.68992511
118Submucous cleft hard palate (HP:0000176)1.68686512
119Ovoid vertebral bodies (HP:0003300)1.68421349
120Generalized amyotrophy (HP:0003700)1.68380489
121Steppage gait (HP:0003376)1.67471820
122Redundant skin (HP:0001582)1.67040725
123Impaired pain sensation (HP:0007328)1.65605872
124Abnormality of pain sensation (HP:0010832)1.65605872
125Deep philtrum (HP:0002002)1.65364635
126Aplasia/Hypoplasia of the hallux (HP:0008362)1.64448089
127Natal tooth (HP:0000695)1.63882451

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK38L3.90768892
2ERBB33.79269935
3DDR23.68965749
4STK243.14202493
5LATS22.85525441
6EPHA32.84023526
7PLK22.74592856
8NEK92.54562753
9TRPM72.51376832
10EPHB22.46507057
11FRK2.46064585
12ZAK2.39695815
13FER2.25983869
14PDGFRA2.21711111
15BCR2.09003567
16SIK32.07881537
17PIM22.07557607
18LIMK12.04974563
19RIPK11.88532313
20CASK1.86043940
21MYLK1.82965729
22BMPR21.76420552
23STK31.71274012
24PRPF4B1.62119920
25FLT31.58745452
26TTN1.57558501
27TESK11.56420425
28PRKCH1.48565916
29STK381.35092485
30LATS11.32186353
31PRKD31.30643456
32MAP2K11.30026382
33SGK21.28223744
34ERBB41.24354623
35MINK11.24268680
36BMPR1B1.23975938
37NTRK11.23792403
38TGFBR21.15530312
39ROCK11.12129495
40PLK31.05670838
41TGFBR11.04177241
42PAK31.02748125
43PAK21.01488631
44PIK3CA1.01161886
45PRKCE0.99985634
46ILK0.99463874
47DAPK30.91785482
48MTOR0.89299305
49PTK2B0.88879594
50MAP3K60.87919165
51TRIB30.86926695
52PRKG20.86563013
53SGK2230.86329547
54SGK4940.86329547
55PAK60.85956416
56ABL20.84311494
57AKT30.81103776
58MAP3K140.80217153
59PTK20.78961791
60MAPK70.78640321
61YES10.77436541
62ICK0.75982635
63SGK30.74924857
64CDK80.74890075
65MAPK130.74179789
66PKN20.71475066
67FGFR40.71138631
68RPS6KA20.70061807
69MELK0.69189014
70KIT0.69048432
71KSR10.68722352
72FGFR30.67803443
73EPHB10.67743820
74FGFR10.66513456
75ARAF0.65463302
76ADRBK10.64057519
77FGFR20.63814614
78EEF2K0.63399836
79NUAK10.62713388
80ROCK20.61599027
81MAP3K120.60327794
82WNK10.60119721
83OBSCN0.59885076
84GSK3A0.57672175
85MET0.57583159
86PDGFRB0.57324717
87CDC42BPA0.55682573
88PRKD20.55673200
89LRRK20.55456376
90MOS0.53774289
91PDK20.52078045
92CLK10.51965931
93ERN10.51620099
94SMG10.50388437
95DYRK20.49822423
96LMTK20.49598887
97MAP3K100.49590163
98PNCK0.48693693
99PAK40.48649060
100EIF2AK20.47269686
101JAK30.46149857
102GRK50.44663486
103CDK120.43439531
104NEK60.42818539
105PAK10.42379464
106PRKD10.42016301
107CAMK1G0.41165231
108EPHA20.37257263
109CAMK2G0.36079098
110MAP3K20.35745488
111DMPK0.34776627
112CDK150.33641198
113INSR0.33082365
114SRC0.32761033
115ADRBK20.32415198
116BMX0.32404526
117TIE10.31093746
118CDK180.30919671
119CDK60.30817230
120CDK11A0.30766608
121MKNK10.30564111
122RPS6KC10.30126487
123RPS6KL10.30126487
124SIK10.30118235
125PTK60.29582228
126NEK20.29254058
127MAPK30.29026046
128PIK3CG0.28621870
129MAPKAPK20.28349277
130GRK70.28103400
131PRKG10.27298993
132CDK140.26994335
133IGF1R0.26511459
134MAP3K30.25716509
135KSR20.25265701
136RAF10.24911322
137SCYL20.24758412
138JAK10.24691116
139RET0.23393081
140MAP3K70.23272842

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045123.80223502
2Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005323.57038038
3Protein digestion and absorption_Homo sapiens_hsa049742.71951392
4Focal adhesion_Homo sapiens_hsa045102.67816102
5Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.42757278
6TGF-beta signaling pathway_Homo sapiens_hsa043502.40805176
7Amoebiasis_Homo sapiens_hsa051462.26934897
8Dilated cardiomyopathy_Homo sapiens_hsa054142.16954977
9Malaria_Homo sapiens_hsa051442.14396265
10AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049332.13210418
11Proteoglycans in cancer_Homo sapiens_hsa052052.10578156
12Hippo signaling pathway_Homo sapiens_hsa043901.90485032
13Melanoma_Homo sapiens_hsa052181.88520601
14Basal cell carcinoma_Homo sapiens_hsa052171.84705443
15Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.84568012
16Glycosaminoglycan degradation_Homo sapiens_hsa005311.84382684
17PI3K-Akt signaling pathway_Homo sapiens_hsa041511.83602436
18Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.80305888
19Adherens junction_Homo sapiens_hsa045201.79916846
20Hedgehog signaling pathway_Homo sapiens_hsa043401.75048355
21Thyroid cancer_Homo sapiens_hsa052161.70695701
22Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.57620383
23Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.48916468
24Endometrial cancer_Homo sapiens_hsa052131.37621822
25Prostate cancer_Homo sapiens_hsa052151.36808287
26Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.30502727
27Arachidonic acid metabolism_Homo sapiens_hsa005901.25757988
28Thyroid hormone synthesis_Homo sapiens_hsa049181.20915053
29Bladder cancer_Homo sapiens_hsa052191.20744944
30Pathways in cancer_Homo sapiens_hsa052001.19874335
31MicroRNAs in cancer_Homo sapiens_hsa052061.19839185
32Small cell lung cancer_Homo sapiens_hsa052221.13598530
33Regulation of actin cytoskeleton_Homo sapiens_hsa048101.10439539
34Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.10411938
35Glioma_Homo sapiens_hsa052141.10063290
36Chronic myeloid leukemia_Homo sapiens_hsa052201.09825248
37Protein export_Homo sapiens_hsa030601.08533569
38Galactose metabolism_Homo sapiens_hsa000521.06632789
39Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.06376121
40Melanogenesis_Homo sapiens_hsa049161.05484872
41Salmonella infection_Homo sapiens_hsa051321.05116454
42Rap1 signaling pathway_Homo sapiens_hsa040151.04693853
43Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.04473453
44Wnt signaling pathway_Homo sapiens_hsa043101.03129287
45Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.03085714
46Axon guidance_Homo sapiens_hsa043601.00905653
47Viral myocarditis_Homo sapiens_hsa054161.00189341
48Starch and sucrose metabolism_Homo sapiens_hsa005000.98290347
49Prion diseases_Homo sapiens_hsa050200.97278031
50TNF signaling pathway_Homo sapiens_hsa046680.97153070
51Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.96010920
52N-Glycan biosynthesis_Homo sapiens_hsa005100.95292818
53Tight junction_Homo sapiens_hsa045300.94244581
54Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.90928807
55Colorectal cancer_Homo sapiens_hsa052100.89691279
56Phagosome_Homo sapiens_hsa041450.88227673
57Central carbon metabolism in cancer_Homo sapiens_hsa052300.84851965
58Phospholipase D signaling pathway_Homo sapiens_hsa040720.83170968
59Pancreatic cancer_Homo sapiens_hsa052120.82114150
60SNARE interactions in vesicular transport_Homo sapiens_hsa041300.80795917
61Toxoplasmosis_Homo sapiens_hsa051450.78459571
62Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.77175588
63Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.77035946
64Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.75658558
65Shigellosis_Homo sapiens_hsa051310.73432546
66Rheumatoid arthritis_Homo sapiens_hsa053230.72537709
67Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.71901229
68p53 signaling pathway_Homo sapiens_hsa041150.71412044
69Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.69722170
70Neurotrophin signaling pathway_Homo sapiens_hsa047220.68101053
71Thyroid hormone signaling pathway_Homo sapiens_hsa049190.67405946
72ErbB signaling pathway_Homo sapiens_hsa040120.66029439
73Notch signaling pathway_Homo sapiens_hsa043300.65276234
74Renal cell carcinoma_Homo sapiens_hsa052110.64875612
75HIF-1 signaling pathway_Homo sapiens_hsa040660.64689754
76Vascular smooth muscle contraction_Homo sapiens_hsa042700.64372190
77Platelet activation_Homo sapiens_hsa046110.64181912
78Ras signaling pathway_Homo sapiens_hsa040140.64021023
79HTLV-I infection_Homo sapiens_hsa051660.62388036
80Leukocyte transendothelial migration_Homo sapiens_hsa046700.61633936
81Hepatitis B_Homo sapiens_hsa051610.60459324
82Endocytosis_Homo sapiens_hsa041440.58751792
83Gap junction_Homo sapiens_hsa045400.58699830
84FoxO signaling pathway_Homo sapiens_hsa040680.56527231
85Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.56002091
86Other glycan degradation_Homo sapiens_hsa005110.55160923
87Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.51677253
88Leishmaniasis_Homo sapiens_hsa051400.51528033
89Legionellosis_Homo sapiens_hsa051340.49133480
90Glutathione metabolism_Homo sapiens_hsa004800.48290356
91Sulfur metabolism_Homo sapiens_hsa009200.48009216
92Vibrio cholerae infection_Homo sapiens_hsa051100.47188539
93Lysine degradation_Homo sapiens_hsa003100.45993144
94Cell cycle_Homo sapiens_hsa041100.45861579
95AMPK signaling pathway_Homo sapiens_hsa041520.45705256
96Apoptosis_Homo sapiens_hsa042100.44745075
97Longevity regulating pathway - mammal_Homo sapiens_hsa042110.44697667
98Cocaine addiction_Homo sapiens_hsa050300.43202168
99Ovarian steroidogenesis_Homo sapiens_hsa049130.42699701
100cGMP-PKG signaling pathway_Homo sapiens_hsa040220.42460955
101Mineral absorption_Homo sapiens_hsa049780.42043162
102Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.41718301
103MAPK signaling pathway_Homo sapiens_hsa040100.41261410
104Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.40921518
105Renin-angiotensin system_Homo sapiens_hsa046140.40485173
106Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.39470223
107Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.39385125
108GnRH signaling pathway_Homo sapiens_hsa049120.38144810
109Insulin signaling pathway_Homo sapiens_hsa049100.36300013
110Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.36237174
111Estrogen signaling pathway_Homo sapiens_hsa049150.35863343
112Acute myeloid leukemia_Homo sapiens_hsa052210.34958775
113Prolactin signaling pathway_Homo sapiens_hsa049170.34829346
114cAMP signaling pathway_Homo sapiens_hsa040240.32197307
115Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.32125135
116Renin secretion_Homo sapiens_hsa049240.31835517
117Complement and coagulation cascades_Homo sapiens_hsa046100.31031124
118Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.30968854
119Pentose phosphate pathway_Homo sapiens_hsa000300.30955026
120Choline metabolism in cancer_Homo sapiens_hsa052310.30322408
121Sphingolipid metabolism_Homo sapiens_hsa006000.29870706
122Pertussis_Homo sapiens_hsa051330.28303097
123Oxytocin signaling pathway_Homo sapiens_hsa049210.27222546
124Aldosterone synthesis and secretion_Homo sapiens_hsa049250.27107627
125mTOR signaling pathway_Homo sapiens_hsa041500.24506324
126Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.24460975
127Lysosome_Homo sapiens_hsa041420.23463692
128Dorso-ventral axis formation_Homo sapiens_hsa043200.23217643

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