FSTL4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1vocalization behavior (GO:0071625)5.57133026
2regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.37659311
3synaptic vesicle exocytosis (GO:0016079)5.30365734
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.28131232
5neuron cell-cell adhesion (GO:0007158)5.17199270
6regulation of short-term neuronal synaptic plasticity (GO:0048172)5.15018616
7protein localization to synapse (GO:0035418)4.94007325
8regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.87472468
9regulation of glutamate receptor signaling pathway (GO:1900449)4.85172719
10glutamate secretion (GO:0014047)4.71883615
11positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.63634154
12neurotransmitter-gated ion channel clustering (GO:0072578)4.61696219
13synaptic vesicle docking involved in exocytosis (GO:0016081)4.60784426
14neuronal action potential propagation (GO:0019227)4.54080176
15regulation of synaptic vesicle exocytosis (GO:2000300)4.46302710
16presynaptic membrane assembly (GO:0097105)4.41866733
17glutamate receptor signaling pathway (GO:0007215)4.34409708
18negative regulation of synaptic transmission, GABAergic (GO:0032229)4.29437236
19ionotropic glutamate receptor signaling pathway (GO:0035235)4.25215262
20neuron-neuron synaptic transmission (GO:0007270)4.17068957
21locomotory exploration behavior (GO:0035641)4.14269327
22gamma-aminobutyric acid signaling pathway (GO:0007214)4.09928994
23synaptic vesicle maturation (GO:0016188)4.09228513
24postsynaptic membrane organization (GO:0001941)4.08355812
25synaptic transmission, glutamatergic (GO:0035249)4.06635423
26presynaptic membrane organization (GO:0097090)4.02675292
27membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.99524061
28G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.99163678
29regulation of synaptic vesicle transport (GO:1902803)3.95315718
30response to histamine (GO:0034776)3.95106435
31neurotransmitter secretion (GO:0007269)3.92765303
32regulation of excitatory postsynaptic membrane potential (GO:0060079)3.88519188
33cerebellar granule cell differentiation (GO:0021707)3.87238642
34regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.86356993
35positive regulation of synapse maturation (GO:0090129)3.85109948
36retinal cone cell development (GO:0046549)3.77989004
37regulation of postsynaptic membrane potential (GO:0060078)3.76282601
38regulation of long-term neuronal synaptic plasticity (GO:0048169)3.73898616
39positive regulation of membrane potential (GO:0045838)3.65727111
40regulation of synaptic transmission, glutamatergic (GO:0051966)3.64923786
41regulation of neuronal synaptic plasticity (GO:0048168)3.63566848
42long-term synaptic potentiation (GO:0060291)3.62739721
43cyclic nucleotide catabolic process (GO:0009214)3.57100689
44neuron recognition (GO:0008038)3.53454487
45striatum development (GO:0021756)3.52003165
46C4-dicarboxylate transport (GO:0015740)3.49918802
47long-term memory (GO:0007616)3.49212719
48behavioral response to cocaine (GO:0048148)3.48375558
49regulation of glutamate secretion (GO:0014048)3.46130889
50regulation of synapse structural plasticity (GO:0051823)3.44872985
51cAMP catabolic process (GO:0006198)3.43338571
52exploration behavior (GO:0035640)3.42419912
53synaptic vesicle endocytosis (GO:0048488)3.37636420
54behavioral response to nicotine (GO:0035095)3.35362413
55short-term memory (GO:0007614)3.35035541
56positive regulation of synapse assembly (GO:0051965)3.33709645
57cerebellar Purkinje cell differentiation (GO:0021702)3.30460169
58regulation of neurotransmitter secretion (GO:0046928)3.29295727
59detection of calcium ion (GO:0005513)3.29048719
60regulation of synaptic plasticity (GO:0048167)3.27873736
61startle response (GO:0001964)3.27712380
62neurotransmitter transport (GO:0006836)3.25376880
63positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.25084346
64positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.25018242
65regulation of dendritic spine morphogenesis (GO:0061001)3.23893674
66detection of light stimulus involved in visual perception (GO:0050908)3.23801347
67detection of light stimulus involved in sensory perception (GO:0050962)3.23801347
68dendritic spine morphogenesis (GO:0060997)3.23257182
69regulation of synapse maturation (GO:0090128)3.21551411
70membrane depolarization (GO:0051899)3.20901108
71positive regulation of neurotransmitter secretion (GO:0001956)3.19179223
72auditory behavior (GO:0031223)3.18967742
73behavioral fear response (GO:0001662)3.18051687
74behavioral defense response (GO:0002209)3.18051687
75serotonin metabolic process (GO:0042428)3.16508505
76gamma-aminobutyric acid transport (GO:0015812)3.15494857
77membrane hyperpolarization (GO:0060081)3.13635902
78transmission of nerve impulse (GO:0019226)3.12833801
79membrane depolarization during action potential (GO:0086010)3.12210967
80regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.10989080
81negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.08111590
82axonal fasciculation (GO:0007413)3.08091071
83mechanosensory behavior (GO:0007638)3.04869068
84fear response (GO:0042596)3.04493812
85synapse assembly (GO:0007416)3.04476386
86response to pheromone (GO:0019236)3.03767618
87primary amino compound metabolic process (GO:1901160)3.03499176
88regulation of neurotransmitter transport (GO:0051588)3.02466165
89synaptic transmission (GO:0007268)3.00371074
90regulation of vesicle fusion (GO:0031338)3.00006906
91proline transport (GO:0015824)2.99811782
92negative regulation of amino acid transport (GO:0051956)2.98855364
93activation of protein kinase A activity (GO:0034199)2.98845125
94G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.98547897
95regulation of dendritic spine development (GO:0060998)2.97180380
96regulation of calcium ion-dependent exocytosis (GO:0017158)2.96212994
97regulation of neurotransmitter levels (GO:0001505)2.95437505
98learning (GO:0007612)2.95147285
99female mating behavior (GO:0060180)2.94261384
100layer formation in cerebral cortex (GO:0021819)2.93843359
101glycine transport (GO:0015816)2.92509194
102positive regulation of neurotransmitter transport (GO:0051590)2.92169892
103regulation of voltage-gated calcium channel activity (GO:1901385)2.91756640
104cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.91653906
105calcium ion-dependent exocytosis (GO:0017156)2.89502291
106DNA methylation involved in gamete generation (GO:0043046)2.88015736
107regulation of female receptivity (GO:0045924)2.87318257
108regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.86741570
109negative regulation of heart rate (GO:0010459)2.86632066
110positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.85198481
111negative regulation of dendrite morphogenesis (GO:0050774)2.84121892
112neuronal action potential (GO:0019228)2.84058154
113positive regulation of synaptic transmission (GO:0050806)2.83891808
114regulation of protein kinase A signaling (GO:0010738)2.83855883
115piRNA metabolic process (GO:0034587)2.83572509
116positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.83334968
117regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.82737791
118regulation of synaptic transmission (GO:0050804)2.81511530
119ATP hydrolysis coupled proton transport (GO:0015991)2.80955105
120regulation of meiosis I (GO:0060631)2.80912128
121inositol phosphate catabolic process (GO:0071545)2.80254280
122inositol phosphate dephosphorylation (GO:0046855)2.77754260
123phosphorylated carbohydrate dephosphorylation (GO:0046838)2.77754260
124positive regulation of meiosis (GO:0045836)2.76556411
125multicellular organism reproduction (GO:0032504)2.75368355
126protein K6-linked ubiquitination (GO:0085020)2.75197684
127protein polyglutamylation (GO:0018095)2.72691471
128negative regulation of cytosolic calcium ion concentration (GO:0051481)2.72385076
129chemosensory behavior (GO:0007635)2.71817466
130aggressive behavior (GO:0002118)2.69106749
131protein K11-linked deubiquitination (GO:0035871)2.67058969
132prepulse inhibition (GO:0060134)2.65674209
133regulation of acrosome reaction (GO:0060046)2.65444905
134neurofilament cytoskeleton organization (GO:0060052)2.62145201
135calcium ion import (GO:0070509)2.61967294
136positive regulation of dendritic spine morphogenesis (GO:0061003)2.59486808
137positive regulation of meiotic cell cycle (GO:0051446)2.56338484
138DNA double-strand break processing (GO:0000729)2.53473776
139neuromuscular process controlling posture (GO:0050884)2.52286289
140cGMP metabolic process (GO:0046068)2.49918699
141adult walking behavior (GO:0007628)2.49701382
142rhodopsin mediated signaling pathway (GO:0016056)2.49109831
143cell differentiation in hindbrain (GO:0021533)2.47943016
144cochlea development (GO:0090102)2.47044003
145righting reflex (GO:0060013)2.44717039
146cellular potassium ion homeostasis (GO:0030007)2.43950240
147protein neddylation (GO:0045116)2.43868468
148acrosome reaction (GO:0007340)2.43521866
149potassium ion transmembrane transport (GO:0071805)2.42836077
150cellular potassium ion transport (GO:0071804)2.42836077
151positive regulation of synaptic transmission, GABAergic (GO:0032230)2.42594311
152auditory receptor cell stereocilium organization (GO:0060088)2.42517927
153long term synaptic depression (GO:0060292)2.39992768
154acidic amino acid transport (GO:0015800)2.37636960
155regulation of microtubule-based movement (GO:0060632)2.36887366

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.38325604
2GBX2_23144817_ChIP-Seq_PC3_Human4.06491630
3* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.08281014
4* JARID2_20064375_ChIP-Seq_MESCs_Mouse3.05910262
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.04621002
6* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.58889896
7* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.58889896
8* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.58389725
9* EZH2_27304074_Chip-Seq_ESCs_Mouse2.54947659
10* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.51298477
11* REST_21632747_ChIP-Seq_MESCs_Mouse2.46254669
12TAF15_26573619_Chip-Seq_HEK293_Human2.46045257
13* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.44126997
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.39841185
15* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.32874262
16* EED_16625203_ChIP-ChIP_MESCs_Mouse2.31392147
17* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.28587891
18* CTBP2_25329375_ChIP-Seq_LNCAP_Human2.28219413
19FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.23549866
20* RARB_27405468_Chip-Seq_BRAIN_Mouse2.18506022
21* RNF2_27304074_Chip-Seq_ESCs_Mouse2.08251372
22* EZH2_27294783_Chip-Seq_ESCs_Mouse2.07807165
23DROSHA_22980978_ChIP-Seq_HELA_Human2.07495120
24* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.07065187
25CTBP1_25329375_ChIP-Seq_LNCAP_Human2.04955046
26ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.00123468
27* REST_18959480_ChIP-ChIP_MESCs_Mouse1.98548869
28NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.96288380
29ZFP57_27257070_Chip-Seq_ESCs_Mouse1.96139942
30* SMAD4_21799915_ChIP-Seq_A2780_Human1.86153696
31GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.84671782
32FLI1_27457419_Chip-Seq_LIVER_Mouse1.80234368
33AR_21572438_ChIP-Seq_LNCaP_Human1.78744846
34IKZF1_21737484_ChIP-ChIP_HCT116_Human1.78317315
35SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.77821214
36E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.77760361
37P300_19829295_ChIP-Seq_ESCs_Human1.76224641
38BMI1_23680149_ChIP-Seq_NPCS_Mouse1.74669384
39GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.74330842
40TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.73270608
41CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.66194687
42FUS_26573619_Chip-Seq_HEK293_Human1.60899944
43SMAD3_21741376_ChIP-Seq_EPCs_Human1.58728603
44CBX2_27304074_Chip-Seq_ESCs_Mouse1.56999587
45PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.56501756
46* EWS_26573619_Chip-Seq_HEK293_Human1.52757674
47PIAS1_25552417_ChIP-Seq_VCAP_Human1.47452982
48* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.47445580
49SMAD_19615063_ChIP-ChIP_OVARY_Human1.47019897
50PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.46706626
51* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.45419248
52MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.44888500
53POU3F2_20337985_ChIP-ChIP_501MEL_Human1.44129851
54TP53_22573176_ChIP-Seq_HFKS_Human1.41859855
55RNF2_27304074_Chip-Seq_NSC_Mouse1.41645935
56MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.38414614
57EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.38320543
58* SOX2_21211035_ChIP-Seq_LN229_Gbm1.37004409
59* AR_25329375_ChIP-Seq_VCAP_Human1.35575023
60CBP_20019798_ChIP-Seq_JUKART_Human1.35461221
61IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.35461221
62VDR_22108803_ChIP-Seq_LS180_Human1.33706123
63* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.32689511
64PCGF2_27294783_Chip-Seq_ESCs_Mouse1.30110539
65TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.28660635
66* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.28250988
67HTT_18923047_ChIP-ChIP_STHdh_Human1.28124286
68BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.28035323
69RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.27660888
70MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.27011855
71* STAT3_23295773_ChIP-Seq_U87_Human1.26698721
72NR3C1_23031785_ChIP-Seq_PC12_Mouse1.26406061
73TCF4_22108803_ChIP-Seq_LS180_Human1.22955547
74P53_22127205_ChIP-Seq_FIBROBLAST_Human1.22432492
75* TCF4_23295773_ChIP-Seq_U87_Human1.21986854
76ER_23166858_ChIP-Seq_MCF-7_Human1.21857167
77ARNT_22903824_ChIP-Seq_MCF-7_Human1.20344662
78IGF1R_20145208_ChIP-Seq_DFB_Human1.18914767
79ZNF274_21170338_ChIP-Seq_K562_Hela1.17741598
80ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.17454405
81* NANOG_19829295_ChIP-Seq_ESCs_Human1.17129217
82* SOX2_19829295_ChIP-Seq_ESCs_Human1.17129217
83AHR_22903824_ChIP-Seq_MCF-7_Human1.16302593
84* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.16061443
85KLF5_20875108_ChIP-Seq_MESCs_Mouse1.15598586
86* CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15241274
87* AR_19668381_ChIP-Seq_PC3_Human1.15035883
88MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.14252784
89RING1B_27294783_Chip-Seq_ESCs_Mouse1.14091171
90PRDM14_20953172_ChIP-Seq_ESCs_Human1.12286132
91AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.11971071
92PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.11918399
93* SMAD4_21741376_ChIP-Seq_EPCs_Human1.11570384
94CDX2_19796622_ChIP-Seq_MESCs_Mouse1.10485975
95* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.10385140
96FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.09139673
97ERG_21242973_ChIP-ChIP_JURKAT_Human1.08196991
98* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.08129776
99* RUNX2_22187159_ChIP-Seq_PCA_Human1.08047924
100EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.07797941
101TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.06243599
102POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.04828087
103TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04828087
104HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.04808944
105NANOG_18555785_Chip-Seq_ESCs_Mouse1.04378159
106* FLI1_21867929_ChIP-Seq_TH2_Mouse1.03904763
107BCAT_22108803_ChIP-Seq_LS180_Human1.02809182
108SUZ12_27294783_Chip-Seq_NPCs_Mouse1.02168345
109EP300_21415370_ChIP-Seq_HL-1_Mouse1.01717757
110RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.00467451
111P53_22387025_ChIP-Seq_ESCs_Mouse0.99911289
112NFE2_27457419_Chip-Seq_LIVER_Mouse0.99173363
113* JUN_21703547_ChIP-Seq_K562_Human0.99061409
114CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.98789331
115TAL1_26923725_Chip-Seq_HPCs_Mouse0.97559433
116RING1B_27294783_Chip-Seq_NPCs_Mouse0.97393985
117NR3C1_21868756_ChIP-Seq_MCF10A_Human0.97264166
118* SOX9_26525672_Chip-Seq_HEART_Mouse0.96488271
119* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96401533
120EZH2_27294783_Chip-Seq_NPCs_Mouse0.96353693
121FOXA1_21572438_ChIP-Seq_LNCaP_Human0.95890038
122* YAP1_20516196_ChIP-Seq_MESCs_Mouse0.95589609
123* WT1_25993318_ChIP-Seq_PODOCYTE_Human0.94223408
124TP53_16413492_ChIP-PET_HCT116_Human0.92951969
125E2F1_18555785_Chip-Seq_ESCs_Mouse0.91786770
126TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.90892790
127TP53_18474530_ChIP-ChIP_U2OS_Human0.90845610
128EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.90291126

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.39404406
2MP0003880_abnormal_central_pattern5.05849832
3MP0003635_abnormal_synaptic_transmissio3.88503153
4MP0009745_abnormal_behavioral_response3.44168054
5MP0009046_muscle_twitch3.16628647
6MP0002063_abnormal_learning/memory/cond3.15187865
7MP0002064_seizures3.11582643
8MP0004270_analgesia3.07648244
9MP0002822_catalepsy3.07349377
10MP0001968_abnormal_touch/_nociception2.90693360
11MP0002572_abnormal_emotion/affect_behav2.82158680
12MP0002272_abnormal_nervous_system2.60288944
13MP0002734_abnormal_mechanical_nocicepti2.47245530
14MP0001486_abnormal_startle_reflex2.38648659
15MP0002735_abnormal_chemical_nociception2.24495702
16MP0002736_abnormal_nociception_after2.21250634
17MP0002837_dystrophic_cardiac_calcinosis2.18553338
18MP0001440_abnormal_grooming_behavior2.16553677
19MP0001984_abnormal_olfaction2.11261055
20MP0001501_abnormal_sleep_pattern2.06885338
21MP0001529_abnormal_vocalization2.06739480
22MP0002067_abnormal_sensory_capabilities2.04608396
23MP0005410_abnormal_fertilization2.00608567
24MP0005423_abnormal_somatic_nervous1.95355067
25MP0005386_behavior/neurological_phenoty1.86645317
26MP0004924_abnormal_behavior1.86645317
27MP0005646_abnormal_pituitary_gland1.81100947
28MP0001970_abnormal_pain_threshold1.80495105
29MP0003787_abnormal_imprinting1.78579767
30MP0000751_myopathy1.77254029
31MP0002557_abnormal_social/conspecific_i1.76992876
32MP0002733_abnormal_thermal_nociception1.73747975
33MP0003718_maternal_effect1.69554092
34MP0002184_abnormal_innervation1.67747866
35MP0009780_abnormal_chondrocyte_physiolo1.65657112
36MP0008569_lethality_at_weaning1.61815300
37MP0003879_abnormal_hair_cell1.60162484
38MP0003122_maternal_imprinting1.60002575
39MP0000778_abnormal_nervous_system1.59814859
40MP0003329_amyloid_beta_deposits1.57814139
41MP0006276_abnormal_autonomic_nervous1.56684278
42MP0004215_abnormal_myocardial_fiber1.52679563
43MP0005253_abnormal_eye_physiology1.51698911
44MP0001188_hyperpigmentation1.49769786
45MP0001905_abnormal_dopamine_level1.49069789
46MP0006035_abnormal_mitochondrial_morpho1.38019628
47MP0008875_abnormal_xenobiotic_pharmacok1.36148062
48MP0004811_abnormal_neuron_physiology1.33911749
49MP0001502_abnormal_circadian_rhythm1.33027657
50MP0002066_abnormal_motor_capabilities/c1.32894015
51MP0002882_abnormal_neuron_morphology1.31929644
52MP0005645_abnormal_hypothalamus_physiol1.27476805
53MP0005551_abnormal_eye_electrophysiolog1.27127286
54MP0004142_abnormal_muscle_tone1.26899922
55MP0004085_abnormal_heartbeat1.25572230
56MP0000372_irregular_coat_pigmentation1.25432453
57MP0004145_abnormal_muscle_electrophysio1.23036944
58MP0000955_abnormal_spinal_cord1.20353835
59MP0004036_abnormal_muscle_relaxation1.19518729
60MP0001986_abnormal_taste_sensitivity1.18849349
61MP0003283_abnormal_digestive_organ1.18215506
62MP0002909_abnormal_adrenal_gland1.17701753
63MP0004084_abnormal_cardiac_muscle1.13971079
64MP0003646_muscle_fatigue1.12307483
65MP0003698_abnormal_male_reproductive1.11021329
66MP0003195_calcinosis1.09821935
67MP0002102_abnormal_ear_morphology1.06400619
68MP0004858_abnormal_nervous_system1.05244327
69MP0003633_abnormal_nervous_system1.05146222
70MP0002876_abnormal_thyroid_physiology1.05105706
71MP0000569_abnormal_digit_pigmentation1.04174819
72MP0004484_altered_response_of1.02994726
73MP0002152_abnormal_brain_morphology1.01855230
74MP0001929_abnormal_gametogenesis1.00095257
75MP0003137_abnormal_impulse_conducting0.99935139
76MP0004742_abnormal_vestibular_system0.98044774
77MP0003631_nervous_system_phenotype0.96608395
78MP0004147_increased_porphyrin_level0.95784224
79MP0002234_abnormal_pharynx_morphology0.94755043
80MP0005394_taste/olfaction_phenotype0.93885448
81MP0005499_abnormal_olfactory_system0.93885448
82MP0004233_abnormal_muscle_weight0.91895538
83MP0003119_abnormal_digestive_system0.91753671
84MP0010386_abnormal_urinary_bladder0.91382501
85MP0002229_neurodegeneration0.91193456
86MP0000631_abnormal_neuroendocrine_gland0.89731182
87MP0008058_abnormal_DNA_repair0.89346559
88MP0001963_abnormal_hearing_physiology0.89072778
89MP0000749_muscle_degeneration0.88240334
90MP0008872_abnormal_physiological_respon0.87711101
91MP0002069_abnormal_eating/drinking_beha0.86581205
92MP0008789_abnormal_olfactory_epithelium0.86409133
93MP0002751_abnormal_autonomic_nervous0.86226326
94MP0008877_abnormal_DNA_methylation0.85832482
95MP0002752_abnormal_somatic_nervous0.85643640
96MP0000383_abnormal_hair_follicle0.85525367
97MP0008874_decreased_physiological_sensi0.84891833
98MP0005075_abnormal_melanosome_morpholog0.83683613
99MP0003121_genomic_imprinting0.82781302
100MP0005620_abnormal_muscle_contractility0.82702097
101MP0001485_abnormal_pinna_reflex0.78772258
102MP0002972_abnormal_cardiac_muscle0.77993870
103MP0000013_abnormal_adipose_tissue0.77497545
104MP0010678_abnormal_skin_adnexa0.77411842
105MP0002090_abnormal_vision0.77204749
106MP0005171_absent_coat_pigmentation0.73720750
107MP0006072_abnormal_retinal_apoptosis0.73348298
108MP0002161_abnormal_fertility/fecundity0.72633166
109MP0000427_abnormal_hair_cycle0.70622924
110MP0005187_abnormal_penis_morphology0.68950033
111MP0002160_abnormal_reproductive_system0.68896750
112MP0000026_abnormal_inner_ear0.67247809
113MP0002638_abnormal_pupillary_reflex0.67032675
114MP0004885_abnormal_endolymph0.65982296
115MP0003632_abnormal_nervous_system0.65969031
116MP0002210_abnormal_sex_determination0.65800649
117MP0006138_congestive_heart_failure0.64121218
118MP0001177_atelectasis0.64082535
119MP0003123_paternal_imprinting0.61130455
120MP0001664_abnormal_digestion0.60918317
121MP0006292_abnormal_olfactory_placode0.59780365
122MP0001943_abnormal_respiration0.58592489
123MP0002653_abnormal_ependyma_morphology0.57987468
124MP0005409_darkened_coat_color0.57397116
125MP0004510_myositis0.56062977
126MP0003634_abnormal_glial_cell0.55957441
127MP0005623_abnormal_meninges_morphology0.55419451

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)8.54820738
2Epileptic encephalopathy (HP:0200134)5.80563289
3Focal seizures (HP:0007359)5.75386824
4Atonic seizures (HP:0010819)5.66770450
5Febrile seizures (HP:0002373)5.51216524
6Myokymia (HP:0002411)5.32613541
7Hyperventilation (HP:0002883)4.71617082
8Absence seizures (HP:0002121)4.37387573
9Visual hallucinations (HP:0002367)4.17287923
10Dialeptic seizures (HP:0011146)4.14559557
11Progressive cerebellar ataxia (HP:0002073)3.90092104
12Generalized tonic-clonic seizures (HP:0002069)3.84197167
13Broad-based gait (HP:0002136)3.75150307
14Gaze-evoked nystagmus (HP:0000640)3.49224078
15Amblyopia (HP:0000646)3.16250748
16Poor eye contact (HP:0000817)3.07870480
17Congenital stationary night blindness (HP:0007642)2.95531783
18Dysdiadochokinesis (HP:0002075)2.79043969
19Truncal ataxia (HP:0002078)2.75965858
20Sudden death (HP:0001699)2.71690125
21Abnormality of macular pigmentation (HP:0008002)2.70579067
22Dysmetric saccades (HP:0000641)2.70141569
23Abnormal social behavior (HP:0012433)2.70130776
24Impaired social interactions (HP:0000735)2.70130776
25Gait imbalance (HP:0002141)2.69585399
26Acute necrotizing encephalopathy (HP:0006965)2.68973307
27Excessive salivation (HP:0003781)2.65011979
28Drooling (HP:0002307)2.65011979
29Horizontal nystagmus (HP:0000666)2.64262858
30Impaired vibration sensation in the lower limbs (HP:0002166)2.62341149
31Abnormal ciliary motility (HP:0012262)2.61509757
32Scanning speech (HP:0002168)2.56962971
33Epileptiform EEG discharges (HP:0011182)2.56415502
34Inability to walk (HP:0002540)2.53690996
35Hypoplasia of the fovea (HP:0007750)2.53643072
36Aplasia/Hypoplasia of the fovea (HP:0008060)2.53643072
37Anxiety (HP:0000739)2.52195928
38Abnormal mitochondria in muscle tissue (HP:0008316)2.49173272
39Oligodactyly (hands) (HP:0001180)2.47887849
40Progressive macrocephaly (HP:0004481)2.44115339
41Dysmetria (HP:0001310)2.43778117
42Syncope (HP:0001279)2.42896670
43Abnormal eating behavior (HP:0100738)2.42688685
44Congenital primary aphakia (HP:0007707)2.41090818
45Urinary bladder sphincter dysfunction (HP:0002839)2.39817113
46Protruding tongue (HP:0010808)2.39170707
47Absent speech (HP:0001344)2.38525202
48Action tremor (HP:0002345)2.38371130
49Pancreatic fibrosis (HP:0100732)2.37828345
50Progressive inability to walk (HP:0002505)2.37050598
51Pheochromocytoma (HP:0002666)2.36232052
52Type II lissencephaly (HP:0007260)2.35140325
53Intention tremor (HP:0002080)2.35017763
54Medial flaring of the eyebrow (HP:0010747)2.34780592
55EEG with generalized epileptiform discharges (HP:0011198)2.30455136
56Molar tooth sign on MRI (HP:0002419)2.27984532
57Abnormality of midbrain morphology (HP:0002418)2.27984532
58Depression (HP:0000716)2.27885193
59Severe visual impairment (HP:0001141)2.26792731
60Abnormality of the fovea (HP:0000493)2.25853291
61Impaired smooth pursuit (HP:0007772)2.24732884
62Genetic anticipation (HP:0003743)2.23332704
63Hemiparesis (HP:0001269)2.22215065
64Prolonged QT interval (HP:0001657)2.21882864
65Limb dystonia (HP:0002451)2.21282198
66Pancreatic cysts (HP:0001737)2.20521491
67Abnormal respiratory motile cilium physiology (HP:0012261)2.20259493
68Hepatic necrosis (HP:0002605)2.19449938
69Muscle hypertrophy of the lower extremities (HP:0008968)2.18191918
70Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.18086612
71Abnormality of alanine metabolism (HP:0010916)2.18086612
72Hyperalaninemia (HP:0003348)2.18086612
73Nephrogenic diabetes insipidus (HP:0009806)2.17498135
74Atrial fibrillation (HP:0005110)2.17124143
75Fetal akinesia sequence (HP:0001989)2.15519699
76Central scotoma (HP:0000603)2.14475235
77Hyperthyroidism (HP:0000836)2.14087707
78Termporal pattern (HP:0011008)2.14025357
79Insidious onset (HP:0003587)2.14025357
80Neuroendocrine neoplasm (HP:0100634)2.10776327
81Mitochondrial inheritance (HP:0001427)2.10172055
82Stereotypic behavior (HP:0000733)2.10149035
83Primary atrial arrhythmia (HP:0001692)2.09710273
84Calf muscle hypertrophy (HP:0008981)2.09329917
85Polyphagia (HP:0002591)2.07262886
86Hypsarrhythmia (HP:0002521)2.07217115
87Genital tract atresia (HP:0001827)2.06519310
88Chronic hepatic failure (HP:0100626)2.05002009
89Left ventricular hypertrophy (HP:0001712)2.02513085
90Ventricular fibrillation (HP:0001663)2.02299472
91Renal cortical cysts (HP:0000803)1.99944725
92Supraventricular tachycardia (HP:0004755)1.99933065
93Retinal dysplasia (HP:0007973)1.99911001
94Vaginal atresia (HP:0000148)1.99877693
95Abnormality of the renal cortex (HP:0011035)1.98302245
96Attenuation of retinal blood vessels (HP:0007843)1.98189980
97Acute encephalopathy (HP:0006846)1.98137517
98Supranuclear gaze palsy (HP:0000605)1.98033245
99Torticollis (HP:0000473)1.97425178
100Hepatocellular necrosis (HP:0001404)1.97148667
101Cerebral hypomyelination (HP:0006808)1.97079642
102Incomplete penetrance (HP:0003829)1.96830061
103Abnormal EKG (HP:0003115)1.95684875
104True hermaphroditism (HP:0010459)1.95533072
105Aplasia/hypoplasia of the uterus (HP:0008684)1.95519622
106Abnormality of the calf musculature (HP:0001430)1.94639441
107Nephronophthisis (HP:0000090)1.94540594
108Abnormality of the labia minora (HP:0012880)1.94277783
109Impaired vibratory sensation (HP:0002495)1.94118938
110Specific learning disability (HP:0001328)1.93775794
111Generalized myoclonic seizures (HP:0002123)1.93012898
112Blue irides (HP:0000635)1.92556962
113Abnormal hair whorl (HP:0010721)1.92186203
114CNS hypomyelination (HP:0003429)1.92002772
115Exercise-induced myalgia (HP:0003738)1.91810012
116Supraventricular arrhythmia (HP:0005115)1.91469158
117Status epilepticus (HP:0002133)1.90680189
118Focal dystonia (HP:0004373)1.90603506
119Agitation (HP:0000713)1.88883446
120Hypoglycemic coma (HP:0001325)1.88748348
121Abnormality of ocular smooth pursuit (HP:0000617)1.88484731
122Postural tremor (HP:0002174)1.88365849
123Aplasia/Hypoplasia of the tibia (HP:0005772)1.87886161
124Dynein arm defect of respiratory motile cilia (HP:0012255)1.86739276
125Absent/shortened dynein arms (HP:0200106)1.86739276
126Abnormality of binocular vision (HP:0011514)1.85743327
127Diplopia (HP:0000651)1.85743327
128Abnormality of the corticospinal tract (HP:0002492)1.82709990
129Optic disc pallor (HP:0000543)1.81857081
130Sensory axonal neuropathy (HP:0003390)1.81518773
131Poor coordination (HP:0002370)1.81306601
132Ankle clonus (HP:0011448)1.80671396
133Postural instability (HP:0002172)1.80567235
134Abnormality of salivation (HP:0100755)1.80292452
135Abnormal rod and cone electroretinograms (HP:0008323)1.78916297
136Tubulointerstitial nephritis (HP:0001970)1.78900453
137Thickened helices (HP:0000391)1.78496055
138Increased CSF lactate (HP:0002490)1.75944716
139Lissencephaly (HP:0001339)1.71408428
140Progressive microcephaly (HP:0000253)1.71076977
141Hypothermia (HP:0002045)1.70633258
142Abnormality of the renal medulla (HP:0100957)1.66486630
143Abnormal drinking behavior (HP:0030082)1.65391327
144Polydipsia (HP:0001959)1.65391327
145Optic nerve hypoplasia (HP:0000609)1.65296347
146Widely spaced teeth (HP:0000687)1.61227304
147Bony spicule pigmentary retinopathy (HP:0007737)1.60586433
148Pachygyria (HP:0001302)1.58753712
149Cystic liver disease (HP:0006706)1.58709413
150Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.58645098
151Ketoacidosis (HP:0001993)1.58595943

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.85402082
2EPHA44.04611020
3FRK3.97406296
4NTRK33.93655516
5BMPR1B3.78527797
6MAP3K93.12852999
7MAP3K42.83427020
8MAP2K72.73506698
9TRIM282.67943867
10DAPK22.56815614
11PRPF4B2.42003749
12MAP4K22.28750347
13NTRK22.25604009
14MAP3K122.13578890
15AKT32.09642577
16PLK22.04062198
17MINK12.03559534
18MARK11.96560201
19TNIK1.89935408
20DAPK11.79537194
21CDK191.77655742
22CSNK1G31.67328884
23ARAF1.65949243
24PAK61.64579153
25ZAK1.64005367
26CAMKK21.63667704
27CSNK1G11.62757756
28MAP2K41.62270418
29PNCK1.61042791
30GRK11.60879754
31INSRR1.60679341
32RIPK41.60283681
33CCNB11.53529116
34BMPR21.50166993
35KSR11.46866261
36CSNK1A1L1.46640179
37MAPK131.45482403
38STK391.44116281
39ACVR1B1.42220960
40CAMKK11.31454519
41NME11.29889387
42GRK51.28741114
43KSR21.26953237
44CDK51.24298331
45CAMK2A1.22925937
46MST41.14459598
47OXSR11.13365363
48PRKCG1.13177776
49BRAF1.12686524
50SGK4941.12193009
51SGK2231.12193009
52SIK31.10651228
53MUSK1.10333171
54SGK21.08465513
55NEK61.05677723
56NTRK11.04209582
57SIK21.01740810
58CAMK2B0.98860881
59UHMK10.98245739
60PDK20.95974795
61WNK40.94596268
62FES0.94193018
63BCR0.92976967
64MAP3K130.90591395
65PTK2B0.89578127
66STK380.88458127
67CAMK10.87520375
68RAF10.86824617
69DYRK1A0.84733975
70MAPKAPK30.83635092
71MYLK0.82162736
72CAMK1G0.81658832
73BCKDK0.81145542
74TLK10.79385902
75OBSCN0.79346610
76PHKG10.78512819
77PHKG20.78512819
78CDK180.76784463
79PRKCE0.75461516
80CAMK2D0.74497495
81CDK140.71707133
82CDK150.69909966
83LATS20.68746171
84PRKCI0.67916781
85NUAK10.67560368
86SGK10.67379198
87ERBB30.67026405
88FGFR20.66925944
89STK110.65676187
90CSNK1D0.63855527
91DAPK30.63228652
92STK38L0.61935778
93PAK30.61317851
94TAOK30.60343477
95CDK11A0.59978560
96SGK30.59099869
97PLK40.55462913
98ROCK20.53111324
99ADRBK20.52966949
100MAPK120.51858430
101DMPK0.51076107
102WNK30.51000231
103CAMK2G0.50530984
104CAMK40.50092591
105FGR0.49463610
106TTK0.49196330
107CDK30.49124991
108MAP2K20.49013661
109BRSK10.48817611
110CDC42BPA0.47411445
111PRKCA0.46622438
112PDK30.45788214
113PDK40.45788214
114TESK20.45575689
115MAP3K20.45332114
116CSNK1A10.45013682
117PKN10.44590213
118ADRBK10.44287345
119MAP3K60.43751652
120PRKD30.42608357
121MARK20.42319152
122LMTK20.42205791
123MOS0.42169354
124FER0.41937623
125DYRK20.41815502
126IRAK10.41365966
127PRKACA0.40832766
128TNK20.40451328
129GRK70.39800312
130PINK10.38435623
131RPS6KA30.38159248
132TYRO30.38053124
133CSNK1G20.37954738
134PRKAA10.37344537
135MAPKAPK50.37266762
136MAP2K10.35757914
137MET0.35534640
138PRKCB0.35055940
139PRKG10.34344963
140CAMK1D0.34295997
141CSNK1E0.34068692
142EIF2AK10.33529780
143PDK10.33223874
144ERBB20.32577460
145PRKCH0.31843093
146BMX0.31161908
147PRKCZ0.30465766

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.20826152
2Synaptic vesicle cycle_Homo sapiens_hsa047213.37115352
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.96262444
4GABAergic synapse_Homo sapiens_hsa047272.78642251
5Circadian entrainment_Homo sapiens_hsa047132.71479449
6Morphine addiction_Homo sapiens_hsa050322.68883041
7Olfactory transduction_Homo sapiens_hsa047402.65469150
8Long-term potentiation_Homo sapiens_hsa047202.55908437
9Glutamatergic synapse_Homo sapiens_hsa047242.48123876
10Nitrogen metabolism_Homo sapiens_hsa009102.40896850
11Amphetamine addiction_Homo sapiens_hsa050312.38501716
12Collecting duct acid secretion_Homo sapiens_hsa049662.28768536
13Cardiac muscle contraction_Homo sapiens_hsa042602.13484958
14Oxidative phosphorylation_Homo sapiens_hsa001902.05781301
15Dopaminergic synapse_Homo sapiens_hsa047282.05622028
16Taste transduction_Homo sapiens_hsa047422.00306763
17Salivary secretion_Homo sapiens_hsa049701.97510381
18Insulin secretion_Homo sapiens_hsa049111.86284683
19Serotonergic synapse_Homo sapiens_hsa047261.84503660
20Cholinergic synapse_Homo sapiens_hsa047251.83447628
21Renin secretion_Homo sapiens_hsa049241.74190783
22Oxytocin signaling pathway_Homo sapiens_hsa049211.73642855
23Long-term depression_Homo sapiens_hsa047301.72459348
24Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.69780863
25Calcium signaling pathway_Homo sapiens_hsa040201.68093607
26Gastric acid secretion_Homo sapiens_hsa049711.66885974
27Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.66359688
28Aldosterone synthesis and secretion_Homo sapiens_hsa049251.63929307
29Maturity onset diabetes of the young_Homo sapiens_hsa049501.63770621
30Alzheimers disease_Homo sapiens_hsa050101.59203839
31Parkinsons disease_Homo sapiens_hsa050121.57136756
32Cocaine addiction_Homo sapiens_hsa050301.42341029
33Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.36576188
34Dilated cardiomyopathy_Homo sapiens_hsa054141.33472254
35Basal transcription factors_Homo sapiens_hsa030221.31782333
36Vibrio cholerae infection_Homo sapiens_hsa051101.30963032
37Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.27454446
38Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.25159712
39Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.23271853
40cAMP signaling pathway_Homo sapiens_hsa040241.23213446
41Regulation of autophagy_Homo sapiens_hsa041401.22059803
42GnRH signaling pathway_Homo sapiens_hsa049121.21618731
43Gap junction_Homo sapiens_hsa045401.19725043
44Huntingtons disease_Homo sapiens_hsa050161.17411826
45Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.14841851
46Phototransduction_Homo sapiens_hsa047441.12172242
47cGMP-PKG signaling pathway_Homo sapiens_hsa040221.08946392
48Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.99565082
49Axon guidance_Homo sapiens_hsa043600.99289452
50Melanogenesis_Homo sapiens_hsa049160.99042911
51Vascular smooth muscle contraction_Homo sapiens_hsa042700.98409713
52Fatty acid elongation_Homo sapiens_hsa000620.97099734
53Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.96880008
54Estrogen signaling pathway_Homo sapiens_hsa049150.95911315
55Primary bile acid biosynthesis_Homo sapiens_hsa001200.94534460
56Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.90974099
57Phosphatidylinositol signaling system_Homo sapiens_hsa040700.89704260
58Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.88848763
59ABC transporters_Homo sapiens_hsa020100.87409661
60Fatty acid biosynthesis_Homo sapiens_hsa000610.87314692
61Type II diabetes mellitus_Homo sapiens_hsa049300.84458016
62Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.84011380
63Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.83172905
64ErbB signaling pathway_Homo sapiens_hsa040120.82688832
65Glioma_Homo sapiens_hsa052140.81694437
66Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.80053550
67beta-Alanine metabolism_Homo sapiens_hsa004100.79672181
68Purine metabolism_Homo sapiens_hsa002300.78437581
69Circadian rhythm_Homo sapiens_hsa047100.77256258
70Glycerolipid metabolism_Homo sapiens_hsa005610.76471686
71Propanoate metabolism_Homo sapiens_hsa006400.76295790
72Fanconi anemia pathway_Homo sapiens_hsa034600.75707239
73Oocyte meiosis_Homo sapiens_hsa041140.74828848
74RNA polymerase_Homo sapiens_hsa030200.74028451
75Pancreatic secretion_Homo sapiens_hsa049720.73090966
76Selenocompound metabolism_Homo sapiens_hsa004500.68513977
77Ether lipid metabolism_Homo sapiens_hsa005650.67491413
78alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.65891690
79MAPK signaling pathway_Homo sapiens_hsa040100.65649411
80Cysteine and methionine metabolism_Homo sapiens_hsa002700.64681394
81Linoleic acid metabolism_Homo sapiens_hsa005910.64672018
82Sphingolipid metabolism_Homo sapiens_hsa006000.63126035
83Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.62605937
84Glycerophospholipid metabolism_Homo sapiens_hsa005640.61877295
85SNARE interactions in vesicular transport_Homo sapiens_hsa041300.60920057
86Steroid biosynthesis_Homo sapiens_hsa001000.60680735
87Thyroid hormone synthesis_Homo sapiens_hsa049180.59351718
88Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.58986542
89Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.57804083
90Steroid hormone biosynthesis_Homo sapiens_hsa001400.57801727
91Phospholipase D signaling pathway_Homo sapiens_hsa040720.57749271
92Homologous recombination_Homo sapiens_hsa034400.57203347
93Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.56806986
94Folate biosynthesis_Homo sapiens_hsa007900.56520739
95Protein export_Homo sapiens_hsa030600.55958055
96Glucagon signaling pathway_Homo sapiens_hsa049220.55749071
97Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.55549639
98Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.55366701
99Type I diabetes mellitus_Homo sapiens_hsa049400.55108782
100Sulfur metabolism_Homo sapiens_hsa009200.53967070
101Proteasome_Homo sapiens_hsa030500.53414020
102Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.53355860
103Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.52555741
104Ras signaling pathway_Homo sapiens_hsa040140.52115962
105Tryptophan metabolism_Homo sapiens_hsa003800.52101105
106Choline metabolism in cancer_Homo sapiens_hsa052310.49769727
107Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.47840651
108Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.47446339
109Fatty acid metabolism_Homo sapiens_hsa012120.46703836
110Rheumatoid arthritis_Homo sapiens_hsa053230.46681652
111Ovarian steroidogenesis_Homo sapiens_hsa049130.46382784
112Wnt signaling pathway_Homo sapiens_hsa043100.46188671
113Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.41096801
114Rap1 signaling pathway_Homo sapiens_hsa040150.40636001
115Alcoholism_Homo sapiens_hsa050340.39644282
116Caffeine metabolism_Homo sapiens_hsa002320.38857260
117Dorso-ventral axis formation_Homo sapiens_hsa043200.37608686
118Metabolic pathways_Homo sapiens_hsa011000.37321881
119Peroxisome_Homo sapiens_hsa041460.37287964
120Renal cell carcinoma_Homo sapiens_hsa052110.36336634
121Mismatch repair_Homo sapiens_hsa034300.36173236
122Inositol phosphate metabolism_Homo sapiens_hsa005620.35010618
123Thyroid hormone signaling pathway_Homo sapiens_hsa049190.34699966
124African trypanosomiasis_Homo sapiens_hsa051430.32801040
125Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.32692013
126Butanoate metabolism_Homo sapiens_hsa006500.31352652
127Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.30792509
128Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.30163520
129Melanoma_Homo sapiens_hsa052180.28732714
130Longevity regulating pathway - mammal_Homo sapiens_hsa042110.27509388
131Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.25752514
132Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.25650444
133VEGF signaling pathway_Homo sapiens_hsa043700.24830974
134Sphingolipid signaling pathway_Homo sapiens_hsa040710.23777180
135Insulin signaling pathway_Homo sapiens_hsa049100.22627137
136Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.22344435
137Endometrial cancer_Homo sapiens_hsa052130.21520341
1382-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.20845045
139Neurotrophin signaling pathway_Homo sapiens_hsa047220.20021362
140Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.19865035

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »