

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of cell killing (GO:0031342) | 9.80527726 |
| 2 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 9.80527726 |
| 3 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 7.00034013 |
| 4 | negative T cell selection (GO:0043383) | 6.26326849 |
| 5 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 6.21615130 |
| 6 | regulation of natural killer cell mediated immunity (GO:0002715) | 6.21615130 |
| 7 | negative thymic T cell selection (GO:0045060) | 6.10890131 |
| 8 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 5.81798361 |
| 9 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 5.50370214 |
| 10 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 5.39527758 |
| 11 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.36822911 |
| 12 | cellular response to interleukin-15 (GO:0071350) | 5.29849123 |
| 13 | response to interleukin-15 (GO:0070672) | 5.28420682 |
| 14 | negative regulation of leukocyte mediated immunity (GO:0002704) | 5.17437304 |
| 15 | T cell migration (GO:0072678) | 5.07144197 |
| 16 | regulation of hypersensitivity (GO:0002883) | 5.00751978 |
| 17 | thymic T cell selection (GO:0045061) | 4.98964286 |
| 18 | leukocyte aggregation (GO:0070486) | 4.96982479 |
| 19 | activated T cell proliferation (GO:0050798) | 4.88887774 |
| 20 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.86557453 |
| 21 | positive thymic T cell selection (GO:0045059) | 4.69090754 |
| 22 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 4.63473114 |
| 23 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 4.60808045 |
| 24 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.55512117 |
| 25 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.43934672 |
| 26 | T cell selection (GO:0045058) | 4.43881893 |
| 27 | negative regulation of innate immune response (GO:0045824) | 4.42979036 |
| 28 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 4.37811506 |
| 29 | positive T cell selection (GO:0043368) | 4.37238022 |
| 30 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.31281456 |
| 31 | negative regulation of T-helper cell differentiation (GO:0045623) | 4.30657988 |
| 32 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 4.30657988 |
| 33 | regulation of T cell receptor signaling pathway (GO:0050856) | 4.23433159 |
| 34 | regulation of cell killing (GO:0031341) | 4.13917513 |
| 35 | positive regulation of antigen processing and presentation (GO:0002579) | 4.12825691 |
| 36 | positive regulation of cell killing (GO:0031343) | 4.12753989 |
| 37 | interferon-gamma production (GO:0032609) | 4.11750947 |
| 38 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 4.06049336 |
| 39 | dendritic cell chemotaxis (GO:0002407) | 4.04625743 |
| 40 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 4.01669717 |
| 41 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.96380041 |
| 42 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.82116035 |
| 43 | lymphocyte migration (GO:0072676) | 3.81460680 |
| 44 | negative regulation of alpha-beta T cell activation (GO:0046636) | 3.72565041 |
| 45 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.68357334 |
| 46 | negative regulation of T cell mediated immunity (GO:0002710) | 3.62601397 |
| 47 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.62315822 |
| 48 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.62085896 |
| 49 | positive regulation of interleukin-4 production (GO:0032753) | 3.58518539 |
| 50 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.54623286 |
| 51 | dendritic cell migration (GO:0036336) | 3.54164258 |
| 52 | natural killer cell differentiation (GO:0001779) | 3.48687530 |
| 53 | cellular extravasation (GO:0045123) | 3.46222631 |
| 54 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.43652799 |
| 55 | regulation of regulatory T cell differentiation (GO:0045589) | 3.43340682 |
| 56 | tolerance induction (GO:0002507) | 3.38826541 |
| 57 | regulation of gamma-delta T cell activation (GO:0046643) | 3.36881315 |
| 58 | regulation of acute inflammatory response to antigenic stimulus (GO:0002864) | 3.35389084 |
| 59 | cellular defense response (GO:0006968) | 3.33463044 |
| 60 | positive regulation of humoral immune response (GO:0002922) | 3.32594958 |
| 61 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.32080867 |
| 62 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.29224605 |
| 63 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.26332820 |
| 64 | positive regulation of DNA recombination (GO:0045911) | 3.26318159 |
| 65 | regulation of antigen processing and presentation (GO:0002577) | 3.26311227 |
| 66 | lymphocyte chemotaxis (GO:0048247) | 3.25887274 |
| 67 | negative regulation of T cell apoptotic process (GO:0070233) | 3.24563377 |
| 68 | negative regulation of type 2 immune response (GO:0002829) | 3.23259351 |
| 69 | T cell receptor signaling pathway (GO:0050852) | 3.23093007 |
| 70 | mast cell activation (GO:0045576) | 3.22322353 |
| 71 | negative regulation of mast cell activation (GO:0033004) | 3.22008505 |
| 72 | negative regulation of adaptive immune response (GO:0002820) | 3.21335748 |
| 73 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.20042738 |
| 74 | regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) | 3.18193050 |
| 75 | cytolysis (GO:0019835) | 3.17729489 |
| 76 | negative regulation of phagocytosis (GO:0050765) | 3.17480714 |
| 77 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 3.17324251 |
| 78 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 3.16847507 |
| 79 | negative regulation of cAMP-mediated signaling (GO:0043951) | 3.14202574 |
| 80 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.10313968 |
| 81 | regulation of interleukin-1 beta secretion (GO:0050706) | 3.10108975 |
| 82 | chemokine-mediated signaling pathway (GO:0070098) | 3.08554109 |
| 83 | neutrophil activation involved in immune response (GO:0002283) | 3.07469802 |
| 84 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 3.06188745 |
| 85 | regulation of alpha-beta T cell activation (GO:0046634) | 3.06003388 |
| 86 | regulation of lymphocyte mediated immunity (GO:0002706) | 3.02961628 |
| 87 | natural killer cell activation (GO:0030101) | 3.01289055 |
| 88 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.00994123 |
| 89 | regulation of T-helper 1 type immune response (GO:0002825) | 2.97565123 |
| 90 | interferon-gamma secretion (GO:0072643) | 2.97209228 |
| 91 | adaptation of signaling pathway (GO:0023058) | 2.94569813 |
| 92 | negative regulation of interleukin-12 production (GO:0032695) | 2.94545908 |
| 93 | regulation of B cell differentiation (GO:0045577) | 2.93791301 |
| 94 | regulation of leukocyte mediated immunity (GO:0002703) | 2.89203834 |
| 95 | positive regulation of granulocyte differentiation (GO:0030854) | 2.87724355 |
| 96 | regulation of interleukin-4 production (GO:0032673) | 2.87411099 |
| 97 | positive regulation of isotype switching (GO:0045830) | 2.86145118 |
| 98 | neutrophil activation (GO:0042119) | 2.85709868 |
| 99 | positive regulation of leukocyte mediated immunity (GO:0002705) | 2.84762022 |
| 100 | regulation of T-helper 1 cell differentiation (GO:0045625) | 2.82879456 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 6.20664985 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.51224035 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.33344334 |
| 4 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.37839182 |
| 5 | RUNX_20019798_ChIP-Seq_JUKART_Human | 4.10400649 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.98988631 |
| 7 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.43049941 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.31765810 |
| 9 | MYB_26560356_Chip-Seq_TH2_Human | 3.07841334 |
| 10 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.04159538 |
| 11 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.97415791 |
| 12 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.83625339 |
| 13 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.82764945 |
| 14 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.50509953 |
| 15 | UTX_26944678_Chip-Seq_JUKART_Human | 2.48511500 |
| 16 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.40572668 |
| 17 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.38564002 |
| 18 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.34056333 |
| 19 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.31434410 |
| 20 | MYB_26560356_Chip-Seq_TH1_Human | 2.29994669 |
| 21 | GATA3_26560356_Chip-Seq_TH2_Human | 2.29626259 |
| 22 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.24519793 |
| 23 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 2.14244571 |
| 24 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.04211741 |
| 25 | MAF_26560356_Chip-Seq_TH1_Human | 2.04096991 |
| 26 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.96867312 |
| 27 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.91679969 |
| 28 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.84846274 |
| 29 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.82907173 |
| 30 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.75933338 |
| 31 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.74195205 |
| 32 | MAF_26560356_Chip-Seq_TH2_Human | 1.73009799 |
| 33 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.63012491 |
| 34 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.60779013 |
| 35 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.59915904 |
| 36 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.55262712 |
| 37 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.52905944 |
| 38 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.51768736 |
| 39 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.47212011 |
| 40 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.41773451 |
| 41 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.39564146 |
| 42 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.37201100 |
| 43 | SPI1_23127762_ChIP-Seq_K562_Human | 1.32508191 |
| 44 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.27309534 |
| 45 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.24458123 |
| 46 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.18954441 |
| 47 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.18742912 |
| 48 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.18561560 |
| 49 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.17894842 |
| 50 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.17542294 |
| 51 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.16610887 |
| 52 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.15020103 |
| 53 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.14098160 |
| 54 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.08685108 |
| 55 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.08583375 |
| 56 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.06187628 |
| 57 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.02832457 |
| 58 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.00120190 |
| 59 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.99801696 |
| 60 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.99661983 |
| 61 | VDR_24763502_ChIP-Seq_THP-1_Human | 0.99448483 |
| 62 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.98412873 |
| 63 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.97204271 |
| 64 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.96305991 |
| 65 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.95482652 |
| 66 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.95260025 |
| 67 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.94777521 |
| 68 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.94561505 |
| 69 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.91997415 |
| 70 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.91496585 |
| 71 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.91236427 |
| 72 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.90985388 |
| 73 | GATA1_19941826_ChIP-Seq_K562_Human | 0.89538000 |
| 74 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.88907420 |
| 75 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.87850062 |
| 76 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.87350847 |
| 77 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.86803178 |
| 78 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.86780010 |
| 79 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.86050842 |
| 80 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.85047878 |
| 81 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.84651370 |
| 82 | GATA3_26560356_Chip-Seq_TH1_Human | 0.84550261 |
| 83 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.84438386 |
| 84 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.84307111 |
| 85 | P300_27268052_Chip-Seq_Bcells_Human | 0.83987140 |
| 86 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.83573760 |
| 87 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.82869972 |
| 88 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.82607027 |
| 89 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.82273273 |
| 90 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.81918341 |
| 91 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.81488063 |
| 92 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.81139785 |
| 93 | MYC_22102868_ChIP-Seq_BL_Human | 0.79944876 |
| 94 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.79620039 |
| 95 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 0.77313219 |
| 96 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.75923443 |
| 97 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.75550146 |
| 98 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.74840232 |
| 99 | SA1_27219007_Chip-Seq_Bcells_Human | 0.74252614 |
| 100 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.73779053 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 5.74930385 |
| 2 | MP0001835_abnormal_antigen_presentation | 4.88582884 |
| 3 | MP0003724_increased_susceptibility_to | 3.51851144 |
| 4 | MP0006082_CNS_inflammation | 3.45482765 |
| 5 | MP0003436_decreased_susceptibility_to | 3.30333466 |
| 6 | MP0005000_abnormal_immune_tolerance | 3.29662588 |
| 7 | MP0001800_abnormal_humoral_immune | 3.21236427 |
| 8 | MP0002148_abnormal_hypersensitivity_rea | 2.95238005 |
| 9 | MP0005025_abnormal_response_to | 2.77306161 |
| 10 | MP0002420_abnormal_adaptive_immunity | 2.76750249 |
| 11 | MP0002723_abnormal_immune_serum | 2.74503577 |
| 12 | MP0001819_abnormal_immune_cell | 2.74113530 |
| 13 | MP0003763_abnormal_thymus_physiology | 2.71362093 |
| 14 | MP0009785_altered_susceptibility_to | 2.69831715 |
| 15 | MP0001790_abnormal_immune_system | 2.60082968 |
| 16 | MP0005387_immune_system_phenotype | 2.60082968 |
| 17 | MP0002452_abnormal_antigen_presenting | 2.59872544 |
| 18 | MP0009333_abnormal_splenocyte_physiolog | 2.46498869 |
| 19 | MP0002419_abnormal_innate_immunity | 2.35074227 |
| 20 | MP0000685_abnormal_immune_system | 2.23094438 |
| 21 | MP0005464_abnormal_platelet_physiology | 2.14789921 |
| 22 | MP0003866_abnormal_defecation | 2.14647078 |
| 23 | MP0002398_abnormal_bone_marrow | 2.14191661 |
| 24 | MP0010155_abnormal_intestine_physiology | 2.05607777 |
| 25 | MP0002166_altered_tumor_susceptibility | 2.03010674 |
| 26 | MP0000716_abnormal_immune_system | 2.02903744 |
| 27 | MP0002163_abnormal_gland_morphology | 2.02027078 |
| 28 | MP0004381_abnormal_hair_follicle | 1.99347144 |
| 29 | MP0000689_abnormal_spleen_morphology | 1.88580972 |
| 30 | MP0000703_abnormal_thymus_morphology | 1.84322941 |
| 31 | MP0001845_abnormal_inflammatory_respons | 1.79319489 |
| 32 | MP0003448_altered_tumor_morphology | 1.79161174 |
| 33 | MP0003045_fibrosis | 1.76663075 |
| 34 | MP0002006_tumorigenesis | 1.75449325 |
| 35 | MP0002722_abnormal_immune_system | 1.75206509 |
| 36 | MP0002405_respiratory_system_inflammati | 1.72157456 |
| 37 | MP0005379_endocrine/exocrine_gland_phen | 1.59020762 |
| 38 | MP0002429_abnormal_blood_cell | 1.57604778 |
| 39 | MP0004947_skin_inflammation | 1.56150097 |
| 40 | MP0008872_abnormal_physiological_respon | 1.53361721 |
| 41 | MP0005310_abnormal_salivary_gland | 1.48015351 |
| 42 | MP0005075_abnormal_melanosome_morpholog | 1.45364288 |
| 43 | MP0001533_abnormal_skeleton_physiology | 1.43217176 |
| 44 | MP0008469_abnormal_protein_level | 1.38692488 |
| 45 | MP0000465_gastrointestinal_hemorrhage | 1.36993408 |
| 46 | MP0005083_abnormal_biliary_tract | 1.31482933 |
| 47 | MP0003183_abnormal_peptide_metabolism | 1.31116297 |
| 48 | MP0003011_delayed_dark_adaptation | 1.27859379 |
| 49 | MP0003300_gastrointestinal_ulcer | 1.24200964 |
| 50 | MP0001986_abnormal_taste_sensitivity | 1.23192844 |
| 51 | MP0003303_peritoneal_inflammation | 1.18482349 |
| 52 | MP0000858_altered_metastatic_potential | 1.17668934 |
| 53 | MP0001348_abnormal_lacrimal_gland | 1.14814730 |
| 54 | MP0009764_decreased_sensitivity_to | 1.12096789 |
| 55 | MP0002396_abnormal_hematopoietic_system | 1.05051659 |
| 56 | MP0004043_abnormal_pH_regulation | 1.02863867 |
| 57 | MP0004142_abnormal_muscle_tone | 1.00690999 |
| 58 | MP0003806_abnormal_nucleotide_metabolis | 1.00296076 |
| 59 | MP0010307_abnormal_tumor_latency | 0.99303168 |
| 60 | MP0002019_abnormal_tumor_incidence | 0.95093006 |
| 61 | MP0001727_abnormal_embryo_implantation | 0.93716611 |
| 62 | MP0008873_increased_physiological_sensi | 0.92039284 |
| 63 | MP0009763_increased_sensitivity_to | 0.91084007 |
| 64 | MP0005166_decreased_susceptibility_to | 0.87597685 |
| 65 | MP0002132_abnormal_respiratory_system | 0.87417902 |
| 66 | MP0002933_joint_inflammation | 0.82298489 |
| 67 | MP0000490_abnormal_crypts_of | 0.81180955 |
| 68 | MP0000015_abnormal_ear_pigmentation | 0.80218624 |
| 69 | MP0001661_extended_life_span | 0.79826703 |
| 70 | MP0002693_abnormal_pancreas_physiology | 0.77742296 |
| 71 | MP0001873_stomach_inflammation | 0.76840684 |
| 72 | MP0002009_preneoplasia | 0.74988636 |
| 73 | MP0001346_abnormal_lacrimal_gland | 0.74094030 |
| 74 | MP0002998_abnormal_bone_remodeling | 0.72850270 |
| 75 | MP0009278_abnormal_bone_marrow | 0.72311950 |
| 76 | MP0005319_abnormal_enzyme/_coenzyme | 0.70986628 |
| 77 | MP0004130_abnormal_muscle_cell | 0.70116987 |
| 78 | MP0001851_eye_inflammation | 0.68673478 |
| 79 | MP0004883_abnormal_blood_vessel | 0.63882068 |
| 80 | MP0005174_abnormal_tail_pigmentation | 0.63542021 |
| 81 | MP0002277_abnormal_respiratory_mucosa | 0.62782219 |
| 82 | MP0001853_heart_inflammation | 0.61662266 |
| 83 | MP0003172_abnormal_lysosome_physiology | 0.60954958 |
| 84 | MP0000343_altered_response_to | 0.57063166 |
| 85 | MP0004145_abnormal_muscle_electrophysio | 0.56491179 |
| 86 | MP0005390_skeleton_phenotype | 0.56046233 |
| 87 | MP0001764_abnormal_homeostasis | 0.55587652 |
| 88 | MP0004808_abnormal_hematopoietic_stem | 0.54296261 |
| 89 | MP0001765_abnormal_ion_homeostasis | 0.53591039 |
| 90 | MP0003252_abnormal_bile_duct | 0.53527222 |
| 91 | MP0002138_abnormal_hepatobiliary_system | 0.52968736 |
| 92 | MP0002168_other_aberrant_phenotype | 0.52513654 |
| 93 | MP0010329_abnormal_lipoprotein_level | 0.50961046 |
| 94 | MP0003191_abnormal_cellular_cholesterol | 0.50855125 |
| 95 | MP0009642_abnormal_blood_homeostasis | 0.50263757 |
| 96 | MP0001663_abnormal_digestive_system | 0.49538310 |
| 97 | MP0005085_abnormal_gallbladder_physiolo | 0.48576708 |
| 98 | MP0003690_abnormal_glial_cell | 0.47897496 |
| 99 | MP0004134_abnormal_chest_morphology | 0.47520683 |
| 100 | MP0008961_abnormal_basal_metabolism | 0.47446516 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Pustule (HP:0200039) | 5.14561077 |
| 2 | Myositis (HP:0100614) | 5.13269856 |
| 3 | Hypoproteinemia (HP:0003075) | 5.00997527 |
| 4 | T lymphocytopenia (HP:0005403) | 4.85441559 |
| 5 | Abnormality of T cell number (HP:0011839) | 4.76990603 |
| 6 | Panhypogammaglobulinemia (HP:0003139) | 4.38638815 |
| 7 | Recurrent bacterial skin infections (HP:0005406) | 4.33249267 |
| 8 | Encephalitis (HP:0002383) | 4.31737000 |
| 9 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.29663285 |
| 10 | Stomatitis (HP:0010280) | 4.10276939 |
| 11 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.07168453 |
| 12 | Abnormality of T cells (HP:0002843) | 4.05174965 |
| 13 | Abnormality of macrophages (HP:0004311) | 3.94124325 |
| 14 | Renal cortical cysts (HP:0000803) | 3.89058283 |
| 15 | Eczematoid dermatitis (HP:0000976) | 3.87726964 |
| 16 | Increased IgM level (HP:0003496) | 3.80961201 |
| 17 | Recurrent abscess formation (HP:0002722) | 3.74747013 |
| 18 | Hemiplegia (HP:0002301) | 3.67072360 |
| 19 | IgG deficiency (HP:0004315) | 3.58141667 |
| 20 | J-shaped sella turcica (HP:0002680) | 3.52494991 |
| 21 | Severe combined immunodeficiency (HP:0004430) | 3.43373332 |
| 22 | Meningitis (HP:0001287) | 3.42725666 |
| 23 | Alveolar cell carcinoma (HP:0006519) | 3.09327727 |
| 24 | Abnormality of T cell physiology (HP:0011840) | 3.06950671 |
| 25 | Recurrent skin infections (HP:0001581) | 2.99643724 |
| 26 | Retrobulbar optic neuritis (HP:0100654) | 2.98714548 |
| 27 | Optic neuritis (HP:0100653) | 2.98714548 |
| 28 | Prolonged bleeding time (HP:0003010) | 2.93874115 |
| 29 | Autoimmune hemolytic anemia (HP:0001890) | 2.92767172 |
| 30 | Recurrent fungal infections (HP:0002841) | 2.89328198 |
| 31 | Petechiae (HP:0000967) | 2.88658879 |
| 32 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.83659666 |
| 33 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.83659666 |
| 34 | Chronic diarrhea (HP:0002028) | 2.82350141 |
| 35 | Gastrointestinal infarctions (HP:0005244) | 2.82051487 |
| 36 | Joint swelling (HP:0001386) | 2.77102566 |
| 37 | Chest pain (HP:0100749) | 2.75541867 |
| 38 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.73862679 |
| 39 | Orchitis (HP:0100796) | 2.68010920 |
| 40 | Increased serum ferritin (HP:0003281) | 2.66930365 |
| 41 | Abnormality of iron homeostasis (HP:0011031) | 2.63807074 |
| 42 | Combined immunodeficiency (HP:0005387) | 2.63611860 |
| 43 | Obstructive lung disease (HP:0006536) | 2.53767943 |
| 44 | Chronic obstructive pulmonary disease (HP:0006510) | 2.53767943 |
| 45 | Pulmonary infiltrates (HP:0002113) | 2.52978916 |
| 46 | Increased CSF protein (HP:0002922) | 2.51676710 |
| 47 | Abnormality of transition element cation homeostasis (HP:0011030) | 2.47011256 |
| 48 | Mediastinal lymphadenopathy (HP:0100721) | 2.46341642 |
| 49 | Tetraplegia (HP:0002445) | 2.45712375 |
| 50 | Epistaxis (HP:0000421) | 2.41146726 |
| 51 | Inflammation of the large intestine (HP:0002037) | 2.40829312 |
| 52 | Gingival bleeding (HP:0000225) | 2.39674413 |
| 53 | Aplastic anemia (HP:0001915) | 2.38478639 |
| 54 | Abnormality of eosinophils (HP:0001879) | 2.35818528 |
| 55 | Purpura (HP:0000979) | 2.34256346 |
| 56 | Elfin facies (HP:0004428) | 2.33463750 |
| 57 | IgM deficiency (HP:0002850) | 2.32967131 |
| 58 | Abnormality of the renal cortex (HP:0011035) | 2.31837751 |
| 59 | Hypochromic anemia (HP:0001931) | 2.31807614 |
| 60 | Hypergammaglobulinemia (HP:0010702) | 2.30879940 |
| 61 | Eosinophilia (HP:0001880) | 2.30133080 |
| 62 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.27449565 |
| 63 | Recurrent cutaneous fungal infections (HP:0011370) | 2.27449565 |
| 64 | Spontaneous hematomas (HP:0007420) | 2.26945512 |
| 65 | Leukocytosis (HP:0001974) | 2.26728134 |
| 66 | Abnormality of the prostate (HP:0008775) | 2.24928243 |
| 67 | 3-Methylglutaconic aciduria (HP:0003535) | 2.23643200 |
| 68 | Granulocytopenia (HP:0001913) | 2.23458435 |
| 69 | Hyperacusis (HP:0010780) | 2.23078058 |
| 70 | Acute hepatic failure (HP:0006554) | 2.22698936 |
| 71 | Chronic hepatic failure (HP:0100626) | 2.20185109 |
| 72 | Vasculitis (HP:0002633) | 2.20134484 |
| 73 | Renovascular hypertension (HP:0100817) | 2.17026998 |
| 74 | Lymphoma (HP:0002665) | 2.16397168 |
| 75 | Recurrent viral infections (HP:0004429) | 2.15818184 |
| 76 | Gastrointestinal inflammation (HP:0004386) | 2.13910973 |
| 77 | Bile duct proliferation (HP:0001408) | 2.07681793 |
| 78 | Abnormal biliary tract physiology (HP:0012439) | 2.07681793 |
| 79 | Arthralgia (HP:0002829) | 2.07657910 |
| 80 | Arterial thrombosis (HP:0004420) | 2.06712037 |
| 81 | Hemoptysis (HP:0002105) | 2.05379123 |
| 82 | Abnormality of oral frenula (HP:0000190) | 2.05277722 |
| 83 | Abnormality of the pleura (HP:0002103) | 2.03368696 |
| 84 | Dysostosis multiplex (HP:0000943) | 2.02805582 |
| 85 | Overriding aorta (HP:0002623) | 2.02092517 |
| 86 | Premature ovarian failure (HP:0008209) | 2.00194633 |
| 87 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.97217177 |
| 88 | Mucopolysacchariduria (HP:0008155) | 1.97217177 |
| 89 | Keratoconjunctivitis sicca (HP:0001097) | 1.94892714 |
| 90 | Recurrent bronchitis (HP:0002837) | 1.93117864 |
| 91 | Increased IgE level (HP:0003212) | 1.92225567 |
| 92 | Hypoalbuminemia (HP:0003073) | 1.92003457 |
| 93 | Abnormal albumin level (HP:0012116) | 1.92003457 |
| 94 | Increased intramyocellular lipid droplets (HP:0012240) | 1.91057166 |
| 95 | Dislocated radial head (HP:0003083) | 1.90959899 |
| 96 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.90567018 |
| 97 | Deformed sella turcica (HP:0002681) | 1.90504997 |
| 98 | Loss of speech (HP:0002371) | 1.87694920 |
| 99 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.86904200 |
| 100 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.86904200 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MUSK | 6.64070479 |
| 2 | TXK | 5.59071336 |
| 3 | MAP4K1 | 3.75097929 |
| 4 | BMPR2 | 3.47081163 |
| 5 | FES | 3.01192141 |
| 6 | TAOK3 | 2.56905576 |
| 7 | MAP3K4 | 2.55702982 |
| 8 | MAP3K14 | 2.24589943 |
| 9 | BTK | 2.22263145 |
| 10 | JAK3 | 2.10036693 |
| 11 | ITK | 2.09266326 |
| 12 | SIK3 | 1.97251180 |
| 13 | KDR | 1.90679969 |
| 14 | TNK2 | 1.86000626 |
| 15 | GRK7 | 1.82285097 |
| 16 | RIPK4 | 1.78112426 |
| 17 | IRAK4 | 1.69396557 |
| 18 | ZAP70 | 1.66218497 |
| 19 | GRK6 | 1.64800810 |
| 20 | LCK | 1.60550504 |
| 21 | JAK1 | 1.55656158 |
| 22 | MARK3 | 1.54890157 |
| 23 | IKBKE | 1.53394583 |
| 24 | TLK1 | 1.51856347 |
| 25 | CSK | 1.50673705 |
| 26 | HCK | 1.48575044 |
| 27 | TBK1 | 1.48491562 |
| 28 | STK10 | 1.46014779 |
| 29 | IKBKB | 1.44520828 |
| 30 | LYN | 1.32605758 |
| 31 | PRKCQ | 1.31638333 |
| 32 | TYK2 | 1.31023617 |
| 33 | SYK | 1.27752612 |
| 34 | ADRBK2 | 1.13943629 |
| 35 | TESK2 | 0.97716326 |
| 36 | NUAK1 | 0.89321696 |
| 37 | TGFBR2 | 0.88393947 |
| 38 | TEC | 0.88257082 |
| 39 | MAPKAPK3 | 0.86711441 |
| 40 | PINK1 | 0.84168702 |
| 41 | BLK | 0.83500108 |
| 42 | ZAK | 0.82443839 |
| 43 | CAMKK2 | 0.82382533 |
| 44 | JAK2 | 0.82138221 |
| 45 | MAPK11 | 0.80620431 |
| 46 | ERBB2 | 0.78008734 |
| 47 | MOS | 0.77387027 |
| 48 | EPHB1 | 0.76868896 |
| 49 | KIT | 0.76861000 |
| 50 | EIF2AK2 | 0.74262993 |
| 51 | CDK4 | 0.73291295 |
| 52 | STK39 | 0.70721969 |
| 53 | LRRK2 | 0.70509969 |
| 54 | GRK5 | 0.70039054 |
| 55 | CSF1R | 0.68760590 |
| 56 | EIF2AK3 | 0.67978934 |
| 57 | PTK6 | 0.66032512 |
| 58 | PIM1 | 0.65165082 |
| 59 | GRK1 | 0.59109429 |
| 60 | NTRK2 | 0.58095620 |
| 61 | MAPK13 | 0.58062486 |
| 62 | SIK2 | 0.56076771 |
| 63 | FGR | 0.55721001 |
| 64 | MAP2K2 | 0.55173693 |
| 65 | TAF1 | 0.53113355 |
| 66 | CDK6 | 0.52206144 |
| 67 | MST4 | 0.51701127 |
| 68 | NEK6 | 0.51426306 |
| 69 | WNK4 | 0.51377224 |
| 70 | MAP3K11 | 0.50080277 |
| 71 | PRKCH | 0.49140041 |
| 72 | ABL1 | 0.44162120 |
| 73 | IGF1R | 0.40765982 |
| 74 | CAMKK1 | 0.38319786 |
| 75 | INSR | 0.32734400 |
| 76 | ERBB3 | 0.31938378 |
| 77 | FYN | 0.31505574 |
| 78 | HIPK2 | 0.30886195 |
| 79 | MAPKAPK2 | 0.30744840 |
| 80 | BCKDK | 0.30559239 |
| 81 | MAP3K5 | 0.30195264 |
| 82 | TYRO3 | 0.29615032 |
| 83 | MATK | 0.29131418 |
| 84 | PDK1 | 0.28233953 |
| 85 | ADRBK1 | 0.27148513 |
| 86 | ILK | 0.26827029 |
| 87 | MAPK12 | 0.26521701 |
| 88 | CDK9 | 0.25645076 |
| 89 | PIK3CG | 0.24941012 |
| 90 | MAPK7 | 0.21840137 |
| 91 | MAP3K12 | 0.21634413 |
| 92 | CLK1 | 0.21183544 |
| 93 | NLK | 0.21095756 |
| 94 | DYRK1B | 0.20576235 |
| 95 | NME1 | 0.19638822 |
| 96 | EPHA3 | 0.19229020 |
| 97 | PRKCD | 0.15624704 |
| 98 | PRPF4B | 0.14986922 |
| 99 | TAOK2 | 0.14741103 |
| 100 | SRC | 0.14051610 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Graft-versus-host disease_Homo sapiens_hsa05332 | 5.54076171 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.79814458 |
| 3 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 4.09517921 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 3.67244793 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.57122956 |
| 6 | Antigen processing and presentation_Homo sapiens_hsa04612 | 3.51055257 |
| 7 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.75220671 |
| 8 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.56162637 |
| 9 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.33588637 |
| 10 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.27106357 |
| 11 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.07514197 |
| 12 | Measles_Homo sapiens_hsa05162 | 2.06859830 |
| 13 | Asthma_Homo sapiens_hsa05310 | 1.94875557 |
| 14 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.91914201 |
| 15 | Viral myocarditis_Homo sapiens_hsa05416 | 1.77296675 |
| 16 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.72725741 |
| 17 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.63502116 |
| 18 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.62082200 |
| 19 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.57798123 |
| 20 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.56488156 |
| 21 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.55713567 |
| 22 | Leishmaniasis_Homo sapiens_hsa05140 | 1.51543646 |
| 23 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.39417355 |
| 24 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.35722284 |
| 25 | Malaria_Homo sapiens_hsa05144 | 1.35367480 |
| 26 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.33089788 |
| 27 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.32121199 |
| 28 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.25247851 |
| 29 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.21534700 |
| 30 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.17913868 |
| 31 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.12775132 |
| 32 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.12439642 |
| 33 | Platelet activation_Homo sapiens_hsa04611 | 1.05968668 |
| 34 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.02567641 |
| 35 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.98900351 |
| 36 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.96740269 |
| 37 | Shigellosis_Homo sapiens_hsa05131 | 0.88615767 |
| 38 | Tuberculosis_Homo sapiens_hsa05152 | 0.84583881 |
| 39 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.82095244 |
| 40 | Apoptosis_Homo sapiens_hsa04210 | 0.78215449 |
| 41 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.77825915 |
| 42 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.77725111 |
| 43 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.77631481 |
| 44 | Influenza A_Homo sapiens_hsa05164 | 0.75056094 |
| 45 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.74880064 |
| 46 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.73927026 |
| 47 | Legionellosis_Homo sapiens_hsa05134 | 0.70624451 |
| 48 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.69387655 |
| 49 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.66235968 |
| 50 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.64324518 |
| 51 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.61588560 |
| 52 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.61477439 |
| 53 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.61302787 |
| 54 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.60582776 |
| 55 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.59057632 |
| 56 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.50546483 |
| 57 | Pertussis_Homo sapiens_hsa05133 | 0.50516511 |
| 58 | RNA degradation_Homo sapiens_hsa03018 | 0.50320277 |
| 59 | HTLV-I infection_Homo sapiens_hsa05166 | 0.49131204 |
| 60 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.49050755 |
| 61 | Peroxisome_Homo sapiens_hsa04146 | 0.47886042 |
| 62 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.45276284 |
| 63 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.45160846 |
| 64 | Proteasome_Homo sapiens_hsa03050 | 0.44573552 |
| 65 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.43909090 |
| 66 | Lysosome_Homo sapiens_hsa04142 | 0.42738706 |
| 67 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.42721556 |
| 68 | Morphine addiction_Homo sapiens_hsa05032 | 0.40555156 |
| 69 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.38748656 |
| 70 | Endocytosis_Homo sapiens_hsa04144 | 0.37372276 |
| 71 | Other glycan degradation_Homo sapiens_hsa00511 | 0.34527523 |
| 72 | Hepatitis B_Homo sapiens_hsa05161 | 0.33349907 |
| 73 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.32680972 |
| 74 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.32360917 |
| 75 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.31435900 |
| 76 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.28778982 |
| 77 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.26909338 |
| 78 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.26813286 |
| 79 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.26167468 |
| 80 | Hepatitis C_Homo sapiens_hsa05160 | 0.25744947 |
| 81 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.24563871 |
| 82 | ABC transporters_Homo sapiens_hsa02010 | 0.24404365 |
| 83 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.24208921 |
| 84 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.22892136 |
| 85 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.22363321 |
| 86 | Salmonella infection_Homo sapiens_hsa05132 | 0.21900320 |
| 87 | Renin secretion_Homo sapiens_hsa04924 | 0.20854293 |
| 88 | Phagosome_Homo sapiens_hsa04145 | 0.19637484 |
| 89 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.19445755 |
| 90 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.18225220 |
| 91 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.17667027 |
| 92 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.16723867 |
| 93 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.16505832 |
| 94 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.16024662 |
| 95 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.14909045 |
| 96 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.14524857 |
| 97 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.13169353 |
| 98 | Insulin resistance_Homo sapiens_hsa04931 | 0.12880408 |
| 99 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.09754306 |
| 100 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.08848446 |

