FTH1P5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1response to gravity (GO:0009629)6.46682461
2cytidine metabolic process (GO:0046087)6.19726539
3cytidine catabolic process (GO:0006216)6.19726539
4cytidine deamination (GO:0009972)6.19726539
5DNA deamination (GO:0045006)5.70238756
6pyrimidine ribonucleoside catabolic process (GO:0046133)5.24263262
7regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450915.13490953
8Arp2/3 complex-mediated actin nucleation (GO:0034314)4.75577775
9mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.52115656
10positive regulation of interleukin-8 secretion (GO:2000484)4.41976324
11sequestering of actin monomers (GO:0042989)4.34770619
12protein maturation by protein folding (GO:0022417)4.13494770
13actin nucleation (GO:0045010)4.10270157
14regulation of skeletal muscle contraction (GO:0014819)4.06371079
15negative regulation of muscle hypertrophy (GO:0014741)3.98618743
16mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.95613047
17eosinophil chemotaxis (GO:0048245)3.88787784
18ATP synthesis coupled proton transport (GO:0015986)3.85651608
19energy coupled proton transport, down electrochemical gradient (GO:0015985)3.85651608
20protein neddylation (GO:0045116)3.79123377
21response to interferon-beta (GO:0035456)3.72039190
22negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.70990697
23regulation of interleukin-8 secretion (GO:2000482)3.67683163
24respiratory electron transport chain (GO:0022904)3.64057550
25electron transport chain (GO:0022900)3.62298190
26platelet dense granule organization (GO:0060155)3.61002299
27skeletal muscle adaptation (GO:0043501)3.58085202
28skeletal muscle tissue regeneration (GO:0043403)3.55820315
29regulation of cellular amino acid metabolic process (GO:0006521)3.53343229
30pyrimidine nucleoside catabolic process (GO:0046135)3.50824476
31eosinophil migration (GO:0072677)3.48272659
32striated muscle atrophy (GO:0014891)3.39846572
33muscle filament sliding (GO:0030049)3.29591708
34actin-myosin filament sliding (GO:0033275)3.29591708
35antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.26681825
36DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.25359478
37negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.23650809
38tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.20435596
39RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.20435596
40antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.16211237
41negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.13932014
42muscle atrophy (GO:0014889)3.13035718
43membrane budding (GO:0006900)3.12447006
44positive regulation of monocyte chemotaxis (GO:0090026)3.11046958
45negative regulation of T cell apoptotic process (GO:0070233)3.09887517
46intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.08074913
47signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.08074913
48signal peptide processing (GO:0006465)3.07973336
49positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.05750631
50signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.02860301
51signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.02860301
52signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.02860301
53negative regulation of viral genome replication (GO:0045071)2.95801917
54macrophage chemotaxis (GO:0048246)2.95075310
55protein complex biogenesis (GO:0070271)2.92563280
56response to testosterone (GO:0033574)2.92161293
57positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.89498691
58viral protein processing (GO:0019082)2.88271954
59signal transduction involved in DNA integrity checkpoint (GO:0072401)2.87173267
60signal transduction involved in DNA damage checkpoint (GO:0072422)2.87173267
61proteasome assembly (GO:0043248)2.83229293
62negative regulation of membrane potential (GO:0045837)2.82426131
63signal transduction involved in cell cycle checkpoint (GO:0072395)2.81994359
64negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.81836193
65negative regulation of ligase activity (GO:0051352)2.81836193
66L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.80756124
67purine nucleotide salvage (GO:0032261)2.80613443
68negative regulation of calcium ion transport into cytosol (GO:0010523)2.78912641
69antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.77221140
70response to muscle activity (GO:0014850)2.75719524
71positive regulation of protein homodimerization activity (GO:0090073)2.73634839
72mannosylation (GO:0097502)2.73153696
73regulation of chronic inflammatory response (GO:0002676)2.72921960
74cellular response to zinc ion (GO:0071294)2.72626931
75GPI anchor biosynthetic process (GO:0006506)2.69484473
76regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.68070605
77GTP biosynthetic process (GO:0006183)2.66998542
78mitochondrial calcium ion homeostasis (GO:0051560)2.66696747
79deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.66015506
80positive regulation of actin filament depolymerization (GO:0030836)2.63028847
81positive regulation of endothelial cell differentiation (GO:0045603)2.60640270
82regulation of T cell receptor signaling pathway (GO:0050856)2.60370042
83mature B cell differentiation (GO:0002335)2.60000775
84GPI anchor metabolic process (GO:0006505)2.59378628
85DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.58221824
86actin-mediated cell contraction (GO:0070252)2.58147750
87positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.57552997
88positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.56011930
89negative regulation by host of viral transcription (GO:0043922)2.55461096
90negative regulation of stress fiber assembly (GO:0051497)2.55121677
91antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.54855827
92negative regulation of cation channel activity (GO:2001258)2.53265556
93positive regulation of prostaglandin secretion (GO:0032308)2.52529498
94regulation of cellular amine metabolic process (GO:0033238)2.48618400
95detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580)2.46753849
96regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902108)2.44929399
97positive regulation of calcium-mediated signaling (GO:0050850)2.44890415
98positive regulation of defense response to virus by host (GO:0002230)2.44536960
99granulocyte activation (GO:0036230)2.43819320
100positive regulation of cell cycle arrest (GO:0071158)2.42306629

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human7.96546004
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat6.60716141
3VDR_22108803_ChIP-Seq_LS180_Human3.85199598
4ELF1_17652178_ChIP-ChIP_JURKAT_Human3.80336447
5IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.51696815
6NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.40735995
7IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.21997122
8E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.06308497
9IRF8_22096565_ChIP-ChIP_GC-B_Human2.92804617
10IRF8_21731497_ChIP-ChIP_J774_Mouse2.80860474
11GABP_17652178_ChIP-ChIP_JURKAT_Human2.54020014
12LYL1_20887958_ChIP-Seq_HPC-7_Mouse2.05120103
13JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.95234372
14EST1_17652178_ChIP-ChIP_JURKAT_Human1.95202535
15STAT4_19710469_ChIP-ChIP_TH1__Mouse1.94889677
16SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.87773457
17RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.84770847
18FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.80085208
19KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.79730020
20CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.75481797
21EZH2_22144423_ChIP-Seq_EOC_Human1.73587616
22PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.70009233
23VDR_23849224_ChIP-Seq_CD4+_Human1.68494362
24PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.63384603
25FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.59974197
26MYB_26560356_Chip-Seq_TH2_Human1.56500309
27TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.48671613
28TAF15_26573619_Chip-Seq_HEK293_Human1.48090114
29TP53_22573176_ChIP-Seq_HFKS_Human1.44082154
30SRF_21415370_ChIP-Seq_HL-1_Mouse1.38261561
31CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.34823751
32LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.33832671
33SRY_22984422_ChIP-ChIP_TESTIS_Rat1.33781458
34CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.33606784
35TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.33417737
36STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.32927668
37BCL6_27268052_Chip-Seq_Bcells_Human1.32254719
38ETS1_20019798_ChIP-Seq_JURKAT_Human1.25113484
39HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.21956653
40ERG_20517297_ChIP-Seq_VCAP_Human1.14657027
41GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.13971744
42PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.13146442
43MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.12986967
44AR_20517297_ChIP-Seq_VCAP_Human1.11669288
45SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.10203093
46FOXA1_27270436_Chip-Seq_PROSTATE_Human1.09776923
47FOXA1_25329375_ChIP-Seq_VCAP_Human1.09776923
48EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.09754746
49HOXB4_20404135_ChIP-ChIP_EML_Mouse1.08693587
50GATA3_27048872_Chip-Seq_THYMUS_Human1.06792621
51RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.06364036
52FOXP3_21729870_ChIP-Seq_TREG_Human1.04960081
53P300_27268052_Chip-Seq_Bcells_Human1.04631295
54SPI1_23547873_ChIP-Seq_NB4_Human1.04054929
55CREB1_15753290_ChIP-ChIP_HEK293T_Human1.03669127
56STAT1_20625510_ChIP-Seq_HELA_Human1.02803615
57ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.02565008
58FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.01725806
59EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.98929425
60SOX2_19829295_ChIP-Seq_ESCs_Human0.98396845
61NANOG_19829295_ChIP-Seq_ESCs_Human0.98396845
62NANOG_20526341_ChIP-Seq_ESCs_Human0.98321024
63EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.96778211
64GATA3_26560356_Chip-Seq_TH2_Human0.96580756
65FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.96296235
66HTT_18923047_ChIP-ChIP_STHdh_Human0.96191421
67MYB_26560356_Chip-Seq_TH1_Human0.95937318
68ZFP57_27257070_Chip-Seq_ESCs_Mouse0.95755867
69TAF2_19829295_ChIP-Seq_ESCs_Human0.95554973
70SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.94969454
71CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.94312210
72FOXA1_21572438_ChIP-Seq_LNCaP_Human0.94205271
73CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.92196331
74MYC_19829295_ChIP-Seq_ESCs_Human0.92045637
75RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.91819534
76RUNX_20019798_ChIP-Seq_JUKART_Human0.91708196
77SOX2_21211035_ChIP-Seq_LN229_Human0.91466533
78CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.90676676
79BMI1_23680149_ChIP-Seq_NPCS_Mouse0.90266538
80BCOR_27268052_Chip-Seq_Bcells_Human0.89073168
81JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.89021687
82POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.88347146
83ELF1_20517297_ChIP-Seq_JURKAT_Human0.86744169
84FOXH1_21741376_ChIP-Seq_EPCs_Human0.86568152
85HIF1A_21447827_ChIP-Seq_MCF-7_Human0.84932626
86YY1_22570637_ChIP-Seq_MALME-3M_Human0.84502075
87CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.84188569
88JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.82671900
89EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.82299436
90GATA3_21878914_ChIP-Seq_MCF-7_Human0.82133536
91IRF8_27001747_Chip-Seq_BMDM_Mouse0.81571855
92CBP_21632823_ChIP-Seq_H3396_Human0.80597536
93PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.79780086
94FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.78796591
95BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.77763043
96AR_21572438_ChIP-Seq_LNCaP_Human0.77093871
97CTCF_20526341_ChIP-Seq_ESCs_Human0.76936755
98EGR1_23403033_ChIP-Seq_LIVER_Mouse0.76174260
99TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.75769232
100CEBPB_22108803_ChIP-Seq_LS180_Human0.75723533

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005671_abnormal_response_to3.91363526
2MP0004145_abnormal_muscle_electrophysio3.40783572
3MP0009785_altered_susceptibility_to2.74959123
4MP0003806_abnormal_nucleotide_metabolis2.66036736
5MP0001835_abnormal_antigen_presentation2.49402069
6MP0002148_abnormal_hypersensitivity_rea2.38941981
7MP0002822_catalepsy2.38261392
8MP0000372_irregular_coat_pigmentation2.34233131
9MP0005464_abnormal_platelet_physiology2.27301836
10MP0003724_increased_susceptibility_to2.25229037
11MP0003646_muscle_fatigue2.01780896
12MP0002095_abnormal_skin_pigmentation1.99899449
13MP0005000_abnormal_immune_tolerance1.94699812
14MP0009764_decreased_sensitivity_to1.89870297
15MP0005083_abnormal_biliary_tract1.88391660
16MP0006072_abnormal_retinal_apoptosis1.85485474
17MP0005085_abnormal_gallbladder_physiolo1.85239309
18MP0001968_abnormal_touch/_nociception1.84086306
19MP0001905_abnormal_dopamine_level1.82252471
20MP0002723_abnormal_immune_serum1.79453591
21MP0004147_increased_porphyrin_level1.77531244
22MP0002277_abnormal_respiratory_mucosa1.75332009
23MP0009379_abnormal_foot_pigmentation1.74249672
24MP0004036_abnormal_muscle_relaxation1.69767266
25MP0004043_abnormal_pH_regulation1.68801140
26MP0000747_muscle_weakness1.66650937
27MP0001800_abnormal_humoral_immune1.65537335
28MP0009333_abnormal_splenocyte_physiolog1.63389579
29MP0002736_abnormal_nociception_after1.62050493
30MP0002837_dystrophic_cardiac_calcinosis1.61738205
31MP0002452_abnormal_antigen_presenting1.57275335
32MP0000685_abnormal_immune_system1.53833187
33MP0003436_decreased_susceptibility_to1.51796130
34MP0005025_abnormal_response_to1.51594134
35MP0002420_abnormal_adaptive_immunity1.51306990
36MP0006082_CNS_inflammation1.50462167
37MP0001819_abnormal_immune_cell1.49050892
38MP0005670_abnormal_white_adipose1.47158826
39MP0003075_altered_response_to1.45709936
40MP0008872_abnormal_physiological_respon1.43772824
41MP0005646_abnormal_pituitary_gland1.42975981
42MP0000569_abnormal_digit_pigmentation1.42276239
43MP0002089_abnormal_postnatal_growth/wei1.31822892
44MP0002876_abnormal_thyroid_physiology1.31756431
45MP0010386_abnormal_urinary_bladder1.30014769
46MP0002102_abnormal_ear_morphology1.27100024
47MP0001542_abnormal_bone_strength1.25834735
48MP0000749_muscle_degeneration1.21122050
49MP0001545_abnormal_hematopoietic_system1.20636699
50MP0005397_hematopoietic_system_phenotyp1.20636699
51MP0004510_myositis1.18589959
52MP0005387_immune_system_phenotype1.17771844
53MP0001790_abnormal_immune_system1.17771844
54MP0008789_abnormal_olfactory_epithelium1.17492804
55MP0008469_abnormal_protein_level1.16975471
56MP0005636_abnormal_mineral_homeostasis1.15837859
57MP0001533_abnormal_skeleton_physiology1.15111429
58MP0009765_abnormal_xenobiotic_induced1.15098576
59MP0002106_abnormal_muscle_physiology1.14903417
60MP0002419_abnormal_innate_immunity1.13352597
61MP0001845_abnormal_inflammatory_respons1.12954536
62MP0005166_decreased_susceptibility_to1.12173252
63MP0008875_abnormal_xenobiotic_pharmacok1.09723364
64MP0000230_abnormal_systemic_arterial1.07348168
65MP0010155_abnormal_intestine_physiology1.06966467
66MP0000716_abnormal_immune_system1.06873292
67MP0002398_abnormal_bone_marrow1.06602003
68MP0000343_altered_response_to1.04747118
69MP0003045_fibrosis1.00733857
70MP0000759_abnormal_skeletal_muscle0.99625229
71MP0001919_abnormal_reproductive_system0.99430059
72MP0009763_increased_sensitivity_to0.99134027
73MP0000751_myopathy0.99055495
74MP0003638_abnormal_response/metabolism_0.98347608
75MP0002269_muscular_atrophy0.97978988
76MP0003880_abnormal_central_pattern0.97908143
77MP0001765_abnormal_ion_homeostasis0.97265110
78MP0005084_abnormal_gallbladder_morpholo0.97220575
79MP0005360_urolithiasis0.97210966
80MP0002166_altered_tumor_susceptibility0.96719590
81MP0006036_abnormal_mitochondrial_physio0.96660125
82MP0005620_abnormal_muscle_contractility0.96507911
83MP0003866_abnormal_defecation0.96399434
84MP0004142_abnormal_muscle_tone0.94894816
85MP0003950_abnormal_plasma_membrane0.94821798
86MP0001970_abnormal_pain_threshold0.91495841
87MP0002735_abnormal_chemical_nociception0.87693731
88MP0001873_stomach_inflammation0.86005136
89MP0009745_abnormal_behavioral_response0.85894277
90MP0000858_altered_metastatic_potential0.85859642
91MP0002733_abnormal_thermal_nociception0.85105128
92MP0004947_skin_inflammation0.83511409
93MP0005165_increased_susceptibility_to0.82716512
94MP0002429_abnormal_blood_cell0.82314886
95MP0000750_abnormal_muscle_regeneration0.81194077
96MP0003763_abnormal_thymus_physiology0.80535236
97MP0006276_abnormal_autonomic_nervous0.80380603
98MP0001853_heart_inflammation0.79837399
99MP0003186_abnormal_redox_activity0.79180429
100MP0001663_abnormal_digestive_system0.77968099

Predicted human phenotypes

RankGene SetZ-score
1Palpebral edema (HP:0100540)4.33255339
2Acute necrotizing encephalopathy (HP:0006965)4.31633812
3Abnormal mitochondria in muscle tissue (HP:0008316)4.11104702
4Mitochondrial inheritance (HP:0001427)3.95610432
5Elevated erythrocyte sedimentation rate (HP:0003565)3.93283971
6Absent rod-and cone-mediated responses on ERG (HP:0007688)3.65208533
7Progressive macrocephaly (HP:0004481)3.61574954
8Hepatocellular necrosis (HP:0001404)3.49243352
9Decreased circulating renin level (HP:0003351)3.42178709
10Decreased activity of mitochondrial respiratory chain (HP:0008972)3.41427069
11Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.41427069
12Acute encephalopathy (HP:0006846)3.28486247
13IgG deficiency (HP:0004315)3.14410485
14Hepatic necrosis (HP:0002605)3.09908269
153-Methylglutaconic aciduria (HP:0003535)3.08406343
16Decreased central vision (HP:0007663)3.07268991
17Increased CSF lactate (HP:0002490)3.04086538
18Nemaline bodies (HP:0003798)3.02446229
19Aplastic anemia (HP:0001915)3.02233504
20Hypoproteinemia (HP:0003075)2.86627348
21Acute hepatic failure (HP:0006554)2.79310455
22Increased intramyocellular lipid droplets (HP:0012240)2.78507801
23Abnormal rod and cone electroretinograms (HP:0008323)2.70594997
24Oligomenorrhea (HP:0000876)2.69863517
25Delayed CNS myelination (HP:0002188)2.66343772
26Periorbital edema (HP:0100539)2.65944301
27Facial edema (HP:0000282)2.60959628
28T lymphocytopenia (HP:0005403)2.60801326
29Increased IgM level (HP:0003496)2.59828183
30Renal Fanconi syndrome (HP:0001994)2.54808527
31Round ear (HP:0100830)2.52453125
32Abnormality of T cell number (HP:0011839)2.45018322
33Decreased electroretinogram (ERG) amplitude (HP:0000654)2.43236874
34Hyperkalemia (HP:0002153)2.39795250
35Generalized aminoaciduria (HP:0002909)2.38907878
36Pendular nystagmus (HP:0012043)2.38011608
37Exercise intolerance (HP:0003546)2.37465626
38Cerebral edema (HP:0002181)2.36414970
39Muscle fiber inclusion bodies (HP:0100299)2.36393374
40Exertional dyspnea (HP:0002875)2.35322386
41Abnormality of the prostate (HP:0008775)2.34716029
42Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.34378656
43Reduced subcutaneous adipose tissue (HP:0003758)2.32502098
44Optic disc pallor (HP:0000543)2.32497245
45Disinhibition (HP:0000734)2.30196535
46Mask-like facies (HP:0000298)2.29066939
47Distal arthrogryposis (HP:0005684)2.27291715
48Attenuation of retinal blood vessels (HP:0007843)2.25297840
49Type I transferrin isoform profile (HP:0003642)2.23634511
50Stomatitis (HP:0010280)2.22691856
51Chronic bronchitis (HP:0004469)2.22052202
52Congenital, generalized hypertrichosis (HP:0004540)2.21942762
53Increased hepatocellular lipid droplets (HP:0006565)2.20555288
54Toxemia of pregnancy (HP:0100603)2.19512678
55Myopathic facies (HP:0002058)2.19395475
56Increased muscle lipid content (HP:0009058)2.19379225
57Absent phalangeal crease (HP:0006109)2.05732464
58Keratoconus (HP:0000563)2.04600616
59Increased corneal curvature (HP:0100692)2.04600616
60Cerebral palsy (HP:0100021)2.03846784
61Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.01662918
62Emotional lability (HP:0000712)2.00663581
63Reduced antithrombin III activity (HP:0001976)1.98139279
64Prolonged neonatal jaundice (HP:0006579)1.97527104
65Congenital stationary night blindness (HP:0007642)1.96947608
66Gastrointestinal infarctions (HP:0005244)1.96680674
67Lactic acidosis (HP:0003128)1.96656606
68Joint swelling (HP:0001386)1.95345367
69Type 2 muscle fiber atrophy (HP:0003554)1.93861427
70X-linked dominant inheritance (HP:0001423)1.93596913
71Exercise-induced myalgia (HP:0003738)1.92205607
72Amyotrophic lateral sclerosis (HP:0007354)1.91819743
73Respiratory failure (HP:0002878)1.91634088
74Hypokalemic alkalosis (HP:0001949)1.91619809
75Erythema (HP:0010783)1.91107527
76Myotonia (HP:0002486)1.90894988
77Purpura (HP:0000979)1.90030947
78Pulmonary infiltrates (HP:0002113)1.87820783
79Lipid accumulation in hepatocytes (HP:0006561)1.85209240
80Abnormal spermatogenesis (HP:0008669)1.84051556
81Mediastinal lymphadenopathy (HP:0100721)1.83883623
82Hypokalemia (HP:0002900)1.83285285
83Hyperactive renin-angiotensin system (HP:0000841)1.83167601
84Retinal dysplasia (HP:0007973)1.82564089
85Poor speech (HP:0002465)1.82211484
86Chronic diarrhea (HP:0002028)1.82031455
87Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.81884274
88Hepatosplenomegaly (HP:0001433)1.81502662
89Abnormality of alanine metabolism (HP:0010916)1.81068947
90Hyperalaninemia (HP:0003348)1.81068947
91Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.81068947
92Vasculitis (HP:0002633)1.80432882
93Increased serum lactate (HP:0002151)1.80373302
94Intrahepatic cholestasis (HP:0001406)1.79962352
95Epistaxis (HP:0000421)1.77009672
96Muscle fiber atrophy (HP:0100295)1.75820584
97Encephalitis (HP:0002383)1.74935033
98Metabolic acidosis (HP:0001942)1.74769499
99Constricted visual fields (HP:0001133)1.74563197
100Petechiae (HP:0000967)1.74356820

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TESK24.90527335
2NME24.20236380
3TESK13.97473180
4LIMK13.33519189
5KDR3.15613317
6MAP3K122.97499517
7TXK2.87092259
8BMPR22.52002956
9SCYL22.38003325
10VRK22.33156661
11TAOK32.13140740
12PIM22.08419656
13PHKG12.06231780
14PHKG22.06231780
15BCKDK1.97560723
16ARAF1.92264193
17MST41.91213986
18ADRBK21.79181736
19LMTK21.41916410
20MYLK1.40306950
21TIE11.37770986
22GRK71.36658046
23MAPKAPK31.34292235
24RIPK41.33229860
25TLK11.31352014
26MAP4K21.28548888
27OBSCN1.20655602
28ERBB31.20146459
29MAP3K111.19422028
30WNK41.18078823
31TNK21.15847616
32CDK191.15546234
33DAPK11.11526059
34MAP4K11.04771356
35CSNK1G31.04503961
36MAP2K70.99689228
37CSF1R0.96631570
38STK160.95530401
39NUAK10.94537036
40CSNK1G20.92758610
41CAMKK20.91173396
42VRK10.88621484
43STK390.87857354
44GRK10.87715632
45CSNK1A1L0.84000869
46ITK0.83180185
47TEC0.81537095
48MATK0.81529404
49CSNK1G10.80291299
50SYK0.80167857
51MAPK130.79504048
52AURKA0.78758038
53DAPK20.74600881
54GRK60.74592134
55JAK30.74121406
56IKBKB0.73517478
57MOS0.71419140
58ABL20.68575346
59ILK0.66934791
60PINK10.64943877
61TAOK20.64444336
62INSRR0.64061977
63OXSR10.64053854
64CSK0.64022980
65ADRBK10.63374964
66DAPK30.61626417
67ZAK0.60995253
68RPS6KA50.59757047
69FES0.55718573
70GRK50.54086216
71MUSK0.53887539
72MINK10.53288816
73TBK10.51777604
74ROCK10.51617128
75CCNB10.51155853
76PAK10.48914206
77DYRK20.45700157
78IKBKE0.45498064
79TRPM70.44656525
80PRKCQ0.43691696
81CAMK2G0.43671722
82BMX0.41359847
83ZAP700.40872038
84PIK3CG0.40669644
85PIM10.40021254
86LYN0.37074528
87PRKCE0.36773066
88PRKACA0.36520313
89MAP3K30.36511255
90BMPR1B0.33758794
91BLK0.32522307
92CDK80.31810920
93LCK0.30919132
94BTK0.29601528
95PRKCA0.29332288
96CSNK1A10.28367769
97PKN10.26093736
98FYN0.25168986
99EPHB20.24017519
100FLT30.23984860

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.58034764
2Oxidative phosphorylation_Homo sapiens_hsa001903.77346091
3Asthma_Homo sapiens_hsa053103.22229332
4Graft-versus-host disease_Homo sapiens_hsa053323.20246923
5Parkinsons disease_Homo sapiens_hsa050123.04001940
6Autoimmune thyroid disease_Homo sapiens_hsa053203.03023432
7Allograft rejection_Homo sapiens_hsa053303.01240511
8Primary immunodeficiency_Homo sapiens_hsa053402.53282243
9Antigen processing and presentation_Homo sapiens_hsa046122.48878769
10Rheumatoid arthritis_Homo sapiens_hsa053232.48531399
11Type I diabetes mellitus_Homo sapiens_hsa049402.38776822
12Alzheimers disease_Homo sapiens_hsa050102.31290381
13Intestinal immune network for IgA production_Homo sapiens_hsa046722.17952289
14Ribosome_Homo sapiens_hsa030102.03788067
15Primary bile acid biosynthesis_Homo sapiens_hsa001201.97902536
16Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.96237575
17Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.95212694
18Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.90138800
19Protein export_Homo sapiens_hsa030601.83858214
20Huntingtons disease_Homo sapiens_hsa050161.80872950
21Cardiac muscle contraction_Homo sapiens_hsa042601.65779581
22Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.62333479
23Viral myocarditis_Homo sapiens_hsa054161.61755620
24Regulation of autophagy_Homo sapiens_hsa041401.59134757
25Hematopoietic cell lineage_Homo sapiens_hsa046401.58747152
26Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.36038739
27Collecting duct acid secretion_Homo sapiens_hsa049661.28354993
28SNARE interactions in vesicular transport_Homo sapiens_hsa041301.27042031
29NF-kappa B signaling pathway_Homo sapiens_hsa040641.26521590
30Salivary secretion_Homo sapiens_hsa049701.18910046
31Shigellosis_Homo sapiens_hsa051311.11889103
32Nitrogen metabolism_Homo sapiens_hsa009101.09043144
33Salmonella infection_Homo sapiens_hsa051321.08057001
34RNA polymerase_Homo sapiens_hsa030201.01829703
35Staphylococcus aureus infection_Homo sapiens_hsa051501.01024809
36Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.98024475
37Glutathione metabolism_Homo sapiens_hsa004800.96551113
38Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.96002679
39Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.92750449
40Phototransduction_Homo sapiens_hsa047440.92748839
41Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.83762966
42Leishmaniasis_Homo sapiens_hsa051400.83638118
43Morphine addiction_Homo sapiens_hsa050320.83107909
44Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.81619197
45Olfactory transduction_Homo sapiens_hsa047400.81073733
46Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.80768490
47T cell receptor signaling pathway_Homo sapiens_hsa046600.78031710
48Chemical carcinogenesis_Homo sapiens_hsa052040.77582189
49Systemic lupus erythematosus_Homo sapiens_hsa053220.75366522
50Legionellosis_Homo sapiens_hsa051340.74208116
51Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.64783012
52Phagosome_Homo sapiens_hsa041450.63709734
53Sulfur metabolism_Homo sapiens_hsa009200.63148137
54Mineral absorption_Homo sapiens_hsa049780.62137169
55Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.61884534
56Drug metabolism - other enzymes_Homo sapiens_hsa009830.61791517
57Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.61374138
58Synaptic vesicle cycle_Homo sapiens_hsa047210.60200186
59Tuberculosis_Homo sapiens_hsa051520.58823467
60Herpes simplex infection_Homo sapiens_hsa051680.58092188
61Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.57857262
62Purine metabolism_Homo sapiens_hsa002300.57629906
63Vibrio cholerae infection_Homo sapiens_hsa051100.57577868
64Pyrimidine metabolism_Homo sapiens_hsa002400.56525123
65Measles_Homo sapiens_hsa051620.55486746
66RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.55201883
67Endocytosis_Homo sapiens_hsa041440.52742603
68GABAergic synapse_Homo sapiens_hsa047270.51362034
69Steroid hormone biosynthesis_Homo sapiens_hsa001400.49604733
70Epstein-Barr virus infection_Homo sapiens_hsa051690.47748215
71Sulfur relay system_Homo sapiens_hsa041220.47639236
72NOD-like receptor signaling pathway_Homo sapiens_hsa046210.45265564
73Taste transduction_Homo sapiens_hsa047420.43198457
74Maturity onset diabetes of the young_Homo sapiens_hsa049500.42950011
75Pertussis_Homo sapiens_hsa051330.41849529
76Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.41340339
77Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.40762786
78Peroxisome_Homo sapiens_hsa041460.40739496
79RNA degradation_Homo sapiens_hsa030180.39784886
80Folate biosynthesis_Homo sapiens_hsa007900.38253027
81Toll-like receptor signaling pathway_Homo sapiens_hsa046200.38238470
82Tight junction_Homo sapiens_hsa045300.36951025
83Caffeine metabolism_Homo sapiens_hsa002320.35616037
84Pentose and glucuronate interconversions_Homo sapiens_hsa000400.35420347
85Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.34319684
86Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.34014192
87Starch and sucrose metabolism_Homo sapiens_hsa005000.33233701
88Influenza A_Homo sapiens_hsa051640.31397956
89Galactose metabolism_Homo sapiens_hsa000520.31106955
90Dopaminergic synapse_Homo sapiens_hsa047280.30853180
91Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.30163672
92Transcriptional misregulation in cancer_Homo sapiens_hsa052020.29369122
93Metabolic pathways_Homo sapiens_hsa011000.28344501
94Retinol metabolism_Homo sapiens_hsa008300.24915477
95Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.24785366
96Arachidonic acid metabolism_Homo sapiens_hsa005900.24099997
97Circadian rhythm_Homo sapiens_hsa047100.21862061
98Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.20665478
99Circadian entrainment_Homo sapiens_hsa047130.20648365
100Serotonergic synapse_Homo sapiens_hsa047260.20037028

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »