FUBP3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of gene silencing by RNA (GO:0060966)4.92339675
2regulation of posttranscriptional gene silencing (GO:0060147)4.92339675
3regulation of gene silencing by miRNA (GO:0060964)4.92339675
4maturation of 5.8S rRNA (GO:0000460)4.81889373
5nuclear pore organization (GO:0006999)4.66295340
6nuclear pore complex assembly (GO:0051292)4.62237456
7paraxial mesoderm development (GO:0048339)4.36036228
8COPI coating of Golgi vesicle (GO:0048205)4.25278251
9Golgi transport vesicle coating (GO:0048200)4.25278251
10protein localization to kinetochore (GO:0034501)4.06280715
11pore complex assembly (GO:0046931)3.82821640
12mitotic chromosome condensation (GO:0007076)3.81014259
13regulation of RNA export from nucleus (GO:0046831)3.80222354
14planar cell polarity pathway involved in neural tube closure (GO:0090179)3.76282065
15IMP biosynthetic process (GO:0006188)3.67537083
16negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)3.62604949
17maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.62309825
18cellular protein complex localization (GO:0034629)3.57929915
19regulation of nucleobase-containing compound transport (GO:0032239)3.53978533
20regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.51530722
21protein complex localization (GO:0031503)3.48762624
22regulation of helicase activity (GO:0051095)3.46269486
23positive regulation of SMAD protein import into nucleus (GO:0060391)3.44791595
24DNA unwinding involved in DNA replication (GO:0006268)3.44464516
25protein retention in ER lumen (GO:0006621)3.44417761
26mitotic metaphase plate congression (GO:0007080)3.39614191
27kinetochore organization (GO:0051383)3.38939911
28mitotic nuclear envelope disassembly (GO:0007077)3.36889840
29DNA replication-dependent nucleosome organization (GO:0034723)3.36320767
30DNA replication-dependent nucleosome assembly (GO:0006335)3.36320767
31adherens junction assembly (GO:0034333)3.36099989
32folic acid-containing compound biosynthetic process (GO:0009396)3.35610603
33RNA stabilization (GO:0043489)3.32097648
34mRNA stabilization (GO:0048255)3.32097648
35notochord development (GO:0030903)3.31633393
36DNA replication initiation (GO:0006270)3.23929252
37regulation of NFAT protein import into nucleus (GO:0051532)3.19985115
38cell-substrate adherens junction assembly (GO:0007045)3.18844079
39focal adhesion assembly (GO:0048041)3.18844079
40skin morphogenesis (GO:0043589)3.15242913
41histone H4-K12 acetylation (GO:0043983)3.13770081
42cranial suture morphogenesis (GO:0060363)3.12732282
43membrane disassembly (GO:0030397)3.12007873
44nuclear envelope disassembly (GO:0051081)3.12007873
45nucleobase biosynthetic process (GO:0046112)3.10840568
46mitotic sister chromatid segregation (GO:0000070)3.10506392
47sister chromatid segregation (GO:0000819)3.09910825
48cytoskeletal anchoring at plasma membrane (GO:0007016)3.07175127
49regulation of glucose import in response to insulin stimulus (GO:2001273)3.06315906
50regulation of SMAD protein import into nucleus (GO:0060390)3.05890466
51spliceosomal tri-snRNP complex assembly (GO:0000244)3.05044045
52regulation of development, heterochronic (GO:0040034)3.01075737
53protein localization to chromosome, centromeric region (GO:0071459)2.98655464
54regulation of telomere maintenance via telomerase (GO:0032210)2.97559704
55protein K6-linked ubiquitination (GO:0085020)2.96923549
56epithelial cell-cell adhesion (GO:0090136)2.96425410
57kinetochore assembly (GO:0051382)2.95516731
58somatic hypermutation of immunoglobulin genes (GO:0016446)2.94769325
59somatic diversification of immune receptors via somatic mutation (GO:0002566)2.94769325
60cell-substrate junction assembly (GO:0007044)2.94328715
61metaphase plate congression (GO:0051310)2.93252736
62retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.92738994
63heterochromatin organization (GO:0070828)2.92597661
64IMP metabolic process (GO:0046040)2.91106278
65negative regulation of DNA repair (GO:0045738)2.90487116
66glucocorticoid receptor signaling pathway (GO:0042921)2.90154741
67anterior/posterior axis specification, embryo (GO:0008595)2.89366418
68regulation of timing of cell differentiation (GO:0048505)2.87167676
69protein localization to microtubule (GO:0035372)2.87091973
70regulation of gene silencing (GO:0060968)2.85471033
71regulation of hippo signaling (GO:0035330)2.85126134
72establishment of integrated proviral latency (GO:0075713)2.83744147
73ribosome biogenesis (GO:0042254)2.82314394
74regulation of early endosome to late endosome transport (GO:2000641)2.82187323
75hippo signaling (GO:0035329)2.81476148
76DNA geometric change (GO:0032392)2.81455989
77DNA duplex unwinding (GO:0032508)2.80979591
78protein localization to endosome (GO:0036010)2.80218816
79regulation of spindle organization (GO:0090224)2.80190430
80spindle checkpoint (GO:0031577)2.79981231
81hemidesmosome assembly (GO:0031581)2.79839411
82craniofacial suture morphogenesis (GO:0097094)2.79163006
83protein export from nucleus (GO:0006611)2.77867751
84purine nucleobase biosynthetic process (GO:0009113)2.75761277
85establishment of chromosome localization (GO:0051303)2.75111269
86establishment of apical/basal cell polarity (GO:0035089)2.74687325
87pre-miRNA processing (GO:0031054)2.74489332
88negative regulation of histone methylation (GO:0031061)2.74099707
89formation of translation preinitiation complex (GO:0001731)2.73467835
90regulation of histone H3-K9 methylation (GO:0051570)2.73290320
91regulation of mammary gland epithelial cell proliferation (GO:0033599)2.72999753
92cell adhesion mediated by integrin (GO:0033627)2.72603038
93positive regulation of mitotic sister chromatid separation (GO:1901970)2.72093773
94positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.72093773
95positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.72093773
96DNA topological change (GO:0006265)2.71770935
97positive regulation of chromosome segregation (GO:0051984)2.71436238
98desmosome organization (GO:0002934)2.69093693
99regulation of centrosome cycle (GO:0046605)2.67816966
100convergent extension (GO:0060026)2.67304585
101DNA strand elongation involved in DNA replication (GO:0006271)2.67187832
102basement membrane organization (GO:0071711)2.66586380
103polarized epithelial cell differentiation (GO:0030859)2.66307707
104chromatin remodeling at centromere (GO:0031055)2.65175234
105negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.64356441
106regulation of nuclear cell cycle DNA replication (GO:0033262)2.63482002
107histone H2B ubiquitination (GO:0033523)2.61379665
108maternal placenta development (GO:0001893)2.60858837
109spindle assembly checkpoint (GO:0071173)2.59747762
110mismatch repair (GO:0006298)2.58953340
111regulation of translational fidelity (GO:0006450)2.58898757
112establishment of monopolar cell polarity (GO:0061162)2.58866029
113establishment or maintenance of monopolar cell polarity (GO:0061339)2.58866029
114mitotic spindle checkpoint (GO:0071174)2.58732151
115mitotic sister chromatid cohesion (GO:0007064)2.58610287
116dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.58104787
117CENP-A containing nucleosome assembly (GO:0034080)2.57730537
118DNA strand elongation (GO:0022616)2.56695373
119mRNA transport (GO:0051028)2.56533060
120regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.56052762
121regulation of mitotic spindle organization (GO:0060236)2.54399629
122embryonic camera-type eye development (GO:0031076)2.53929797
123ribosome assembly (GO:0042255)2.53462096
124regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.53186937
125vesicle coating (GO:0006901)2.51847102
126COPII vesicle coating (GO:0048208)2.50797715
127negative regulation of mRNA processing (GO:0050686)2.50601438
128Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.50221523
129negative regulation of chromosome segregation (GO:0051985)2.50041131
130cellular response to epidermal growth factor stimulus (GO:0071364)2.49785570
131chromatin assembly (GO:0031497)2.49222476
132regulation of mitotic metaphase/anaphase transition (GO:0030071)2.48480806
133regulation of chromatin binding (GO:0035561)2.47908199
134negative regulation of mRNA metabolic process (GO:1903312)2.47642258
135regulation of double-strand break repair (GO:2000779)2.46908050
136DNA replication checkpoint (GO:0000076)2.46002062
137telomere maintenance via semi-conservative replication (GO:0032201)2.45706252
138regulation of mRNA stability (GO:0043488)2.45527506
139mitotic spindle assembly checkpoint (GO:0007094)2.45405296
140activation of Rac GTPase activity (GO:0032863)2.44889249
141negative regulation of mitotic sister chromatid separation (GO:2000816)2.43765021
142negative regulation of mitotic sister chromatid segregation (GO:0033048)2.43765021
143negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.43765021
144negative regulation of sister chromatid segregation (GO:0033046)2.43765021
145cell migration involved in sprouting angiogenesis (GO:0002042)2.42657552
146protein localization to chromosome (GO:0034502)2.42327847
147DNA replication-independent nucleosome assembly (GO:0006336)2.41824695
148DNA replication-independent nucleosome organization (GO:0034724)2.41824695
149nucleotide-excision repair, DNA gap filling (GO:0006297)2.41025327
150RNA splicing, via transesterification reactions (GO:0000375)2.40904320
151nucleosome disassembly (GO:0006337)2.40686175
152protein-DNA complex disassembly (GO:0032986)2.40686175
153regulation of establishment of planar polarity (GO:0090175)2.40636381
154proline biosynthetic process (GO:0006561)2.40591811
155activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.38516141
156NLS-bearing protein import into nucleus (GO:0006607)2.38360405
157regulation of translational termination (GO:0006449)2.38245672
158embryonic process involved in female pregnancy (GO:0060136)2.38017660
159positive regulation of nuclease activity (GO:0032075)2.37719655
160gap junction assembly (GO:0016264)2.36823506
161chromosome condensation (GO:0030261)2.36078798
162morphogenesis of an epithelial sheet (GO:0002011)2.34111503
163eye morphogenesis (GO:0048592)2.33652894
164ER-nucleus signaling pathway (GO:0006984)2.29605647
165regulation of sister chromatid cohesion (GO:0007063)2.29512964
166response to epidermal growth factor (GO:0070849)2.28993792
167peptidyl-arginine omega-N-methylation (GO:0035247)2.28698752
168regulation of histone H3-K27 methylation (GO:0061085)2.28605514
169pentose-phosphate shunt (GO:0006098)2.28598961
170corticosteroid receptor signaling pathway (GO:0031958)2.27669838
171establishment or maintenance of apical/basal cell polarity (GO:0035088)2.27451196
172establishment or maintenance of bipolar cell polarity (GO:0061245)2.27451196
173endoplasmic reticulum unfolded protein response (GO:0030968)2.23837649

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.61410329
2FOXM1_23109430_ChIP-Seq_U2OS_Human3.88111408
3SALL1_21062744_ChIP-ChIP_HESCs_Human3.61455205
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.48487549
5RBPJ_22232070_ChIP-Seq_NCS_Mouse3.43119203
6KLF2_18264089_ChIP-ChIP_MESCs_Mouse3.36136062
7KLF5_18264089_ChIP-ChIP_MESCs_Mouse3.36136062
8KLF4_18264089_ChIP-ChIP_MESCs_Mouse3.36136062
9E2F4_17652178_ChIP-ChIP_JURKAT_Human3.31238261
10* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.99931088
11FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.88614184
12CLOCK_20551151_ChIP-Seq_293T_Human2.86543393
13NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.86395744
14HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.69611647
15EGR1_19374776_ChIP-ChIP_THP-1_Human2.53502591
16MYC_19030024_ChIP-ChIP_MESCs_Mouse2.52119987
17MYC_19079543_ChIP-ChIP_MESCs_Mouse2.50407019
18AR_21909140_ChIP-Seq_LNCAP_Human2.49632982
19POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.49066040
20ZNF263_19887448_ChIP-Seq_K562_Human2.46209527
21NELFA_20434984_ChIP-Seq_ESCs_Mouse2.34075792
22* SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.30899972
23* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.28442677
24SOX2_18555785_ChIP-Seq_MESCs_Mouse2.18858552
25MYC_22102868_ChIP-Seq_BL_Human2.18545163
26TCF3_18467660_ChIP-ChIP_MESCs_Mouse2.13840739
27* NANOG_18555785_ChIP-Seq_MESCs_Mouse2.12363155
28ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.11498891
29* SOX2_18358816_ChIP-ChIP_MESCs_Mouse2.11111235
30TP63_19390658_ChIP-ChIP_HaCaT_Human2.09408237
31WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.09323109
32TCF3_18692474_ChIP-Seq_MEFs_Mouse2.08387335
33SALL4_18804426_ChIP-ChIP_MESCs_Mouse2.02542847
34TP63_17297297_ChIP-ChIP_HaCaT_Human1.99773196
35* POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.95517923
36* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.93648596
37ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.92412130
38* TCF3_18692474_ChIP-Seq_MESCs_Mouse1.92240701
39CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.92209503
40* NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.89323557
41* PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.88237786
42KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.84077412
43E2F1_21310950_ChIP-Seq_MCF-7_Human1.82003234
44KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.78613526
45* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.75378069
46ZFP281_18757296_ChIP-ChIP_E14_Mouse1.70904819
47ELK3_25401928_ChIP-Seq_HUVEC_Human1.70495497
48* SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.70109934
49DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.69641033
50RARG_19884340_ChIP-ChIP_MEFs_Mouse1.68928818
51P300_27058665_Chip-Seq_ZR-75-30cells_Human1.68428932
52* POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.66634606
53MYCN_18555785_ChIP-Seq_MESCs_Mouse1.65152632
54* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.60948237
55CREB1_15753290_ChIP-ChIP_HEK293T_Human1.59873565
56EST1_17652178_ChIP-ChIP_JURKAT_Human1.59012411
57ESR1_15608294_ChIP-ChIP_MCF-7_Human1.57872382
58E2F1_18555785_ChIP-Seq_MESCs_Mouse1.57582096
59EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.57306967
60* ELK1_19687146_ChIP-ChIP_HELA_Human1.57269295
61RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.57217214
62CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.55675308
63YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.54691973
64PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.51644875
65* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.51383875
66RACK7_27058665_Chip-Seq_MCF-7_Human1.50744972
67HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.49896033
68* KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.49782279
69KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.49680583
70NANOG_16153702_ChIP-ChIP_HESCs_Human1.47216065
71* NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.46633096
72XRN2_22483619_ChIP-Seq_HELA_Human1.46217852
73KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.46203903
74MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.44042536
75POU5F1_16153702_ChIP-ChIP_HESCs_Human1.43804123
76* NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.43258241
77TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.42639441
78CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.40957204
79EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.37752010
80STAT3_1855785_ChIP-Seq_MESCs_Mouse1.36298846
81KDM2B_26808549_Chip-Seq_K562_Human1.34533177
82NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.32600917
83CHD1_26751641_Chip-Seq_LNCaP_Human1.32454966
84ATF3_27146783_Chip-Seq_COLON_Human1.31841097
85TCF7_22412390_ChIP-Seq_EML_Mouse1.31129101
86* NANOG_21062744_ChIP-ChIP_HESCs_Human1.30765935
87TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.28185513
88* TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.26549906
89ZFP281_27345836_Chip-Seq_ESCs_Mouse1.25793565
90* SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.24968937
91TTF2_22483619_ChIP-Seq_HELA_Human1.24115484
92SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.23090215
93* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.23004144
94EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.22678604
95TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.21172227
96TRIM28_21343339_ChIP-Seq_HEK293_Human1.21070375
97* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.21021994
98SOX2_18692474_ChIP-Seq_MEFs_Mouse1.20105472
99NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.19847043
100CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.19802252
101TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.19695709
102SALL4_18804426_ChIP-ChIP_XEN_Mouse1.19604874
103UBF1/2_26484160_Chip-Seq_HMECs_Human1.19486347
104* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.18175284
105ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.17846631
106STAT6_21828071_ChIP-Seq_BEAS2B_Human1.17757110
107KDM2B_26808549_Chip-Seq_SUP-B15_Human1.17379752
108SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.17048594
109DCP1A_22483619_ChIP-Seq_HELA_Human1.16908844
110CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.16647441
111* SOX2_18692474_ChIP-Seq_MESCs_Mouse1.16606922
112HIF1A_21447827_ChIP-Seq_MCF-7_Human1.15019731
113HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.14299984
114PADI4_21655091_ChIP-ChIP_MCF-7_Human1.14089320
115GABP_17652178_ChIP-ChIP_JURKAT_Human1.13964030
116NANOG_18692474_ChIP-Seq_MEFs_Mouse1.13882008
117TFEB_21752829_ChIP-Seq_HELA_Human1.13610157
118SOX17_20123909_ChIP-Seq_XEN_Mouse1.13448114
119SOX2_16153702_ChIP-ChIP_HESCs_Human1.12992164
120* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.12094436
121* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.12094436
122ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.10082364
123KDM2B_26808549_Chip-Seq_DND41_Human1.10058215
124* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.10047903
125TRIM28_19339689_ChIP-ChIP_MESCs_Mouse1.09042456
126ETS1_20019798_ChIP-Seq_JURKAT_Human1.08336595
127VDR_23849224_ChIP-Seq_CD4+_Human1.07694254
128KDM5A_27292631_Chip-Seq_BREAST_Human1.07670819
129* NANOG_18692474_ChIP-Seq_MESCs_Mouse1.07650349
130WT1_19549856_ChIP-ChIP_CCG9911_Human1.07218648
131POU5F1_16518401_ChIP-PET_MESCs_Mouse1.06517751
132PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.06431877
133UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.04341021
134* SOX9_24532713_ChIP-Seq_HFSC_Mouse1.03850494
135KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.03123220
136* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.02803342
137NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.01963780
138LXR_22292898_ChIP-Seq_THP-1_Human1.01846887
139EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.01390280
140ESR2_21235772_ChIP-Seq_MCF-7_Human1.01221011
141* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.01047196
142THAP11_20581084_ChIP-Seq_MESCs_Mouse1.00555067
143ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.99603478
144TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.96229763
145* KLF4_18555785_ChIP-Seq_MESCs_Mouse0.95897358
146HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.94846862
147SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.93560492
148FOXP3_21729870_ChIP-Seq_TREG_Human0.92339634
149FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.90667182
150NANOG_16518401_ChIP-PET_MESCs_Mouse0.89330073
151BRD4_25478319_ChIP-Seq_HGPS_Human0.89261831
152* PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.88197155

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010234_abnormal_vibrissa_follicle2.84854552
2MP0003941_abnormal_skin_development2.74668793
3MP0008057_abnormal_DNA_replication2.71977216
4MP0010352_gastrointestinal_tract_polyps2.69866887
5MP0004957_abnormal_blastocyst_morpholog2.59194877
6MP0010030_abnormal_orbit_morphology2.56346120
7MP0010094_abnormal_chromosome_stability2.54323788
8MP0003693_abnormal_embryo_hatching2.42088922
9MP0008007_abnormal_cellular_replicative2.33786358
10MP0003077_abnormal_cell_cycle2.29263757
11MP0003111_abnormal_nucleus_morphology2.23702743
12MP0005623_abnormal_meninges_morphology2.08071603
13MP0002877_abnormal_melanocyte_morpholog2.04113661
14MP0003705_abnormal_hypodermis_morpholog2.03733473
15MP0008438_abnormal_cutaneous_collagen1.99555034
16MP0003123_paternal_imprinting1.99148826
17MP0008932_abnormal_embryonic_tissue1.90396205
18MP0000350_abnormal_cell_proliferation1.84466209
19MP0004185_abnormal_adipocyte_glucose1.83098449
20MP0005076_abnormal_cell_differentiation1.82968691
21MP0004197_abnormal_fetal_growth/weight/1.79256285
22MP0001293_anophthalmia1.75636593
23MP0000566_synostosis1.74731820
24MP0001730_embryonic_growth_arrest1.73480795
25MP0003937_abnormal_limbs/digits/tail_de1.72942820
26MP0005367_renal/urinary_system_phenotyp1.72034519
27MP0000516_abnormal_urinary_system1.72034519
28MP0002084_abnormal_developmental_patter1.71420897
29MP0003121_genomic_imprinting1.70359755
30MP0002085_abnormal_embryonic_tissue1.67181575
31MP0005409_darkened_coat_color1.66090260
32MP0009053_abnormal_anal_canal1.65895948
33MP0004233_abnormal_muscle_weight1.65567522
34MP0001672_abnormal_embryogenesis/_devel1.65143737
35MP0005380_embryogenesis_phenotype1.65143737
36MP0009672_abnormal_birth_weight1.63202924
37MP0000579_abnormal_nail_morphology1.62527361
38MP0000428_abnormal_craniofacial_morphol1.62079583
39MP0008058_abnormal_DNA_repair1.61727033
40MP0003890_abnormal_embryonic-extraembry1.60715446
41MP0003091_abnormal_cell_migration1.58354001
42MP0003755_abnormal_palate_morphology1.58039826
43MP0000537_abnormal_urethra_morphology1.57910510
44MP0002653_abnormal_ependyma_morphology1.56311730
45MP0001697_abnormal_embryo_size1.53664591
46MP0002249_abnormal_larynx_morphology1.52353338
47MP0004272_abnormal_basement_membrane1.51988905
48MP0000049_abnormal_middle_ear1.50625008
49MP0003119_abnormal_digestive_system1.49477525
50MP0002796_impaired_skin_barrier1.49202698
51MP0002111_abnormal_tail_morphology1.48497284
52MP0002086_abnormal_extraembryonic_tissu1.47847288
53MP0002060_abnormal_skin_morphology1.46276725
54MP0003984_embryonic_growth_retardation1.46261559
55MP0003942_abnormal_urinary_system1.45358888
56MP0002088_abnormal_embryonic_growth/wei1.44817685
57MP0004133_heterotaxia1.44212742
58MP0003453_abnormal_keratinocyte_physiol1.43631977
59MP0005171_absent_coat_pigmentation1.43190508
60MP0002009_preneoplasia1.41461325
61MP0006292_abnormal_olfactory_placode1.40358177
62MP0003385_abnormal_body_wall1.40277168
63MP0004858_abnormal_nervous_system1.40177179
64MP0000432_abnormal_head_morphology1.40124294
65MP0010307_abnormal_tumor_latency1.39649180
66MP0003935_abnormal_craniofacial_develop1.32358351
67MP0000003_abnormal_adipose_tissue1.31594836
68MP0005503_abnormal_tendon_morphology1.31312639
69MP0005501_abnormal_skin_physiology1.30953766
70MP0002697_abnormal_eye_size1.30411674
71MP0001286_abnormal_eye_development1.30364076
72MP0005508_abnormal_skeleton_morphology1.27715096
73MP0005257_abnormal_intraocular_pressure1.24053588
74MP0009250_abnormal_appendicular_skeleto1.23178042
75MP0001299_abnormal_eye_distance/1.22702035
76MP0000534_abnormal_ureter_morphology1.22507588
77MP0002938_white_spotting1.21805147
78MP0001849_ear_inflammation1.18673075
79MP0003115_abnormal_respiratory_system1.18669273
80MP0003567_abnormal_fetal_cardiomyocyte1.18136219
81MP0001915_intracranial_hemorrhage1.17440707
82MP0002089_abnormal_postnatal_growth/wei1.17182206
83MP0003283_abnormal_digestive_organ1.17166410
84MP0003786_premature_aging1.15307985
85MP0002080_prenatal_lethality1.15159093
86MP0002233_abnormal_nose_morphology1.14956024
87MP0003950_abnormal_plasma_membrane1.13703806
88MP0004264_abnormal_extraembryonic_tissu1.10598858
89MP0010630_abnormal_cardiac_muscle1.07222994
90MP0002896_abnormal_bone_mineralization1.06678627
91MP0003122_maternal_imprinting1.06523501
92MP0002116_abnormal_craniofacial_bone1.06207470
93MP0003566_abnormal_cell_adhesion1.05749397
94MP0000733_abnormal_muscle_development1.05399160
95MP0009384_cardiac_valve_regurgitation1.04503309
96MP0005451_abnormal_body_composition1.03560493
97MP0005275_abnormal_skin_tensile1.02959774
98MP0005621_abnormal_cell_physiology1.01306560
99MP0003315_abnormal_perineum_morphology1.01185775
100MP0000762_abnormal_tongue_morphology1.00339445
101MP0006054_spinal_hemorrhage1.00304316
102MP0002109_abnormal_limb_morphology0.99052328
103MP0002932_abnormal_joint_morphology0.98945477
104MP0002092_abnormal_eye_morphology0.98770710
105MP0002282_abnormal_trachea_morphology0.97769034
106MP0005023_abnormal_wound_healing0.97524088
107MP0005248_abnormal_Harderian_gland0.97437856
108MP0005375_adipose_tissue_phenotype0.96695660
109MP0002751_abnormal_autonomic_nervous0.96470371
110MP0010368_abnormal_lymphatic_system0.96150509
111MP0002114_abnormal_axial_skeleton0.95666118
112MP0003936_abnormal_reproductive_system0.94543418
113MP0009703_decreased_birth_body0.94196188
114MP0004808_abnormal_hematopoietic_stem0.93571732
115MP0005666_abnormal_adipose_tissue0.93422632
116MP0003279_aneurysm0.93280873
117MP0002177_abnormal_outer_ear0.91526842
118MP0002925_abnormal_cardiovascular_devel0.91253862
119MP0000462_abnormal_digestive_system0.88412222
120MP0003861_abnormal_nervous_system0.87363788
121MP0004087_abnormal_muscle_fiber0.87022319
122MP0003136_yellow_coat_color0.86507220
123MP0008877_abnormal_DNA_methylation0.84201404
124MP0001216_abnormal_epidermal_layer0.83496797
125MP0000678_abnormal_parathyroid_gland0.83285284
126MP0004782_abnormal_surfactant_physiolog0.83009085
127MP0000377_abnormal_hair_follicle0.81051595
128MP0001348_abnormal_lacrimal_gland0.80997355
129MP0001661_extended_life_span0.80982785
130MP0000163_abnormal_cartilage_morphology0.80717026
131MP0003806_abnormal_nucleotide_metabolis0.80683158
132MP0005197_abnormal_uvea_morphology0.79962421
133MP0000627_abnormal_mammary_gland0.79902351
134MP0005384_cellular_phenotype0.79898423
135MP0001340_abnormal_eyelid_morphology0.79823089
136MP0003221_abnormal_cardiomyocyte_apopto0.78466391
137MP0001958_emphysema0.78453967
138MP0010678_abnormal_skin_adnexa0.78038581
139MP0000747_muscle_weakness0.77573595
140MP0000313_abnormal_cell_death0.76449266
141MP0003938_abnormal_ear_development0.76029762

Predicted human phenotypes

RankGene SetZ-score
1Hyperacusis (HP:0010780)3.23544551
2Supernumerary spleens (HP:0009799)3.00955516
3Abnormality of the labia minora (HP:0012880)2.94334212
4Ependymoma (HP:0002888)2.83475968
5Ulnar bowing (HP:0003031)2.74409213
6Absent radius (HP:0003974)2.72700412
7Insomnia (HP:0100785)2.68133790
8Aplasia involving forearm bones (HP:0009822)2.61714866
9Absent forearm bone (HP:0003953)2.61714866
10Chromsome breakage (HP:0040012)2.60958035
11Missing ribs (HP:0000921)2.58861697
12Atrophic scars (HP:0001075)2.57718589
13Rib fusion (HP:0000902)2.56594551
14Neoplasm of the oral cavity (HP:0100649)2.54794041
15Sparse lateral eyebrow (HP:0005338)2.53904552
16Arterial tortuosity (HP:0005116)2.51783719
17Astrocytoma (HP:0009592)2.50717522
18Abnormality of the astrocytes (HP:0100707)2.50717522
19Selective tooth agenesis (HP:0001592)2.49016936
20Deviation of the thumb (HP:0009603)2.43334096
21Ankyloglossia (HP:0010296)2.43207941
22Vertebral arch anomaly (HP:0008438)2.40630297
23Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.39976532
24Short 4th metacarpal (HP:0010044)2.39976532
25Vascular tortuosity (HP:0004948)2.39188320
26Aplasia/hypoplasia of the humerus (HP:0006507)2.37856855
27Chromosomal breakage induced by crosslinking agents (HP:0003221)2.36183156
28Volvulus (HP:0002580)2.34136411
29Achilles tendon contracture (HP:0001771)2.33923852
30Birth length less than 3rd percentile (HP:0003561)2.33147342
31Insidious onset (HP:0003587)2.33135482
32Termporal pattern (HP:0011008)2.33135482
33Medulloblastoma (HP:0002885)2.31226615
34Short humerus (HP:0005792)2.30928981
35Ectopic kidney (HP:0000086)2.30639185
36Fragile skin (HP:0001030)2.30131170
37Atresia of the external auditory canal (HP:0000413)2.25447475
38Back pain (HP:0003418)2.24533235
39Abnormality of the anterior horn cell (HP:0006802)2.24253925
40Degeneration of anterior horn cells (HP:0002398)2.24253925
41Bladder diverticulum (HP:0000015)2.23460564
42Glioma (HP:0009733)2.22874241
43Patellar aplasia (HP:0006443)2.20231615
44Proximal placement of thumb (HP:0009623)2.17496244
45Aplasia/Hypoplasia of the sternum (HP:0006714)2.17165938
46Breast hypoplasia (HP:0003187)2.15220097
47Overriding aorta (HP:0002623)2.14907808
48Mitral valve prolapse (HP:0001634)2.14557068
49Renal duplication (HP:0000075)2.14339930
50Fused cervical vertebrae (HP:0002949)2.13983694
51Premature rupture of membranes (HP:0001788)2.11839699
52Abnormality of the Achilles tendon (HP:0005109)2.11686624
53Biconcave vertebral bodies (HP:0004586)2.11500670
54Flat acetabular roof (HP:0003180)2.10942260
55Impulsivity (HP:0100710)2.09693546
56Aplasia/Hypoplasia of the patella (HP:0006498)2.07395679
57Rhabdomyosarcoma (HP:0002859)2.07094074
58Abnormality of oral frenula (HP:0000190)2.06954719
59Hemivertebrae (HP:0002937)2.05377678
60Arnold-Chiari malformation (HP:0002308)2.04784965
61Genu recurvatum (HP:0002816)2.03239782
62Shawl scrotum (HP:0000049)2.03043861
63Vertebral hypoplasia (HP:0008417)2.02440576
64Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.02440576
65Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.01252800
66Turricephaly (HP:0000262)2.01216510
67Abnormal lung lobation (HP:0002101)2.00859103
68Disproportionate tall stature (HP:0001519)1.99368102
69Adrenal hypoplasia (HP:0000835)1.99198724
70Wormian bones (HP:0002645)1.96901903
71Vertebral compression fractures (HP:0002953)1.94207324
72Esophageal atresia (HP:0002032)1.94027308
73Rectovaginal fistula (HP:0000143)1.93462909
74Rectal fistula (HP:0100590)1.93462909
75Broad face (HP:0000283)1.93443644
76Protrusio acetabuli (HP:0003179)1.93347193
77Nephroblastoma (Wilms tumor) (HP:0002667)1.92977791
78Vertebral clefting (HP:0008428)1.91664219
79Pseudobulbar signs (HP:0002200)1.91567337
80Mitral regurgitation (HP:0001653)1.91378321
81Embryonal renal neoplasm (HP:0011794)1.90986447
82Long palpebral fissure (HP:0000637)1.89364918
83Elfin facies (HP:0004428)1.89257339
84Advanced eruption of teeth (HP:0006288)1.87766767
85Dysmetric saccades (HP:0000641)1.87201630
86Abnormality of dentin (HP:0010299)1.87014625
87Hypoplastic ischia (HP:0003175)1.86926858
88Abnormality of the ischium (HP:0003174)1.86844103
89Supernumerary ribs (HP:0005815)1.85960077
90Supernumerary bones of the axial skeleton (HP:0009144)1.85831543
91Spastic diplegia (HP:0001264)1.85778516
92Osteolytic defects of the phalanges of the hand (HP:0009771)1.85218356
93Osteolytic defects of the hand bones (HP:0009699)1.85218356
94Short nail (HP:0001799)1.85204587
95Agnosia (HP:0010524)1.83793917
96Synostosis of carpal bones (HP:0005048)1.83701878
97Intestinal fistula (HP:0100819)1.83509044
98Shallow orbits (HP:0000586)1.83123185
99Broad thumb (HP:0011304)1.82768966
100Skull defect (HP:0001362)1.82261513
101Hammertoe (HP:0001765)1.80497853
10211 pairs of ribs (HP:0000878)1.79777727
103Abnormality of the distal phalanx of the thumb (HP:0009617)1.79353805
104Spinal rigidity (HP:0003306)1.78950371
105Patellar dislocation (HP:0002999)1.78263817
106Aplasia involving bones of the extremities (HP:0009825)1.77382292
107Aplasia involving bones of the upper limbs (HP:0009823)1.77382292
108Aplasia of the phalanges of the hand (HP:0009802)1.77382292
109Neoplasm of striated muscle (HP:0009728)1.77355327
110Colon cancer (HP:0003003)1.77225555
111Stenosis of the external auditory canal (HP:0000402)1.76701508
112Deep philtrum (HP:0002002)1.75720606
113Mesomelia (HP:0003027)1.75480719
114Bowel diverticulosis (HP:0005222)1.75286764
115Coronal craniosynostosis (HP:0004440)1.74982719
116Distal upper limb amyotrophy (HP:0007149)1.74746739
117Upper limb amyotrophy (HP:0009129)1.74746739
118Facial cleft (HP:0002006)1.74477029
119Abnormality of abdominal situs (HP:0011620)1.73926015
120Abdominal situs inversus (HP:0003363)1.73926015
121Hyperextensible skin (HP:0000974)1.72366177
122Neonatal short-limb short stature (HP:0008921)1.72039258
123Short palpebral fissure (HP:0012745)1.71044738
124Natal tooth (HP:0000695)1.70387081
125Distal lower limb amyotrophy (HP:0008944)1.69970899
126Carpal synostosis (HP:0009702)1.69688129
127Thin ribs (HP:0000883)1.69605024
128Cerebral aneurysm (HP:0004944)1.69288215
129Relative macrocephaly (HP:0004482)1.69044846
130Overlapping toe (HP:0001845)1.68821919
131Abnormality of the phalanges of the hallux (HP:0010057)1.67551325
132Abnormal ossification of hand bones (HP:0005921)1.67443052
133Cortical dysplasia (HP:0002539)1.67319388
134Gastrointestinal atresia (HP:0002589)1.67301434
135Wide anterior fontanel (HP:0000260)1.67276757
136Bilateral microphthalmos (HP:0007633)1.66713854
137Cubitus valgus (HP:0002967)1.66255990
138Meckel diverticulum (HP:0002245)1.65604445
139Abnormality of the 4th metacarpal (HP:0010012)1.65516178
140Cystic hygroma (HP:0000476)1.65295366
141Spinal cord lesions (HP:0100561)1.65079685
142Syringomyelia (HP:0003396)1.65079685
143Renovascular hypertension (HP:0100817)1.64924401
144Cerebral inclusion bodies (HP:0100314)1.63727441
145Midface retrusion (HP:0011800)1.60986900
146Glossoptosis (HP:0000162)1.60556350
147Preaxial foot polydactyly (HP:0001841)1.60108267
148Ovarian neoplasm (HP:0100615)1.59640568
149Vertebral fusion (HP:0002948)1.59600550
150Broad long bones (HP:0005622)1.59082240
151Gastrointestinal carcinoma (HP:0002672)1.59069664
152Malignant gastrointestinal tract tumors (HP:0006749)1.59069664
153Blue sclerae (HP:0000592)1.58998191
154Increased nuchal translucency (HP:0010880)1.58772766
155Soft skin (HP:0000977)1.58493649
156Broad metatarsal (HP:0001783)1.58192086
157Abnormality of the ileum (HP:0001549)1.57636302
158Urethral obstruction (HP:0000796)1.57568801
159Hypoplastic labia majora (HP:0000059)1.57455295
160Asymmetry of the thorax (HP:0001555)1.57047926
161Broad phalanges of the hand (HP:0009768)1.56823259
162Renal hypoplasia (HP:0000089)1.56705395
163Flat cornea (HP:0007720)1.56510640
164Breech presentation (HP:0001623)1.56459897
165Right ventricular cardiomyopathy (HP:0011663)1.55806575
166Orthostatic hypotension (HP:0001278)1.55677061
167Ankle contracture (HP:0006466)1.55593159
168Abnormality of the calcaneus (HP:0008364)1.55065978
169Deviation of the hallux (HP:0010051)1.53912414
170Heterotopia (HP:0002282)1.53547263
171Bronchomalacia (HP:0002780)1.53163774
172Abnormality of the acetabulum (HP:0003170)1.52889578
173Cervical subluxation (HP:0003308)1.52841236
174Abnormality of carpal bone ossification (HP:0006257)1.52654002
175Joint laxity (HP:0001388)1.52195851
176Abnormality of the salivary glands (HP:0010286)1.51833978
177Increased connective tissue (HP:0009025)1.51780074
178Lower limb amyotrophy (HP:0007210)1.49810248
179Aortic dissection (HP:0002647)1.49616225

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK123.64983426
2EPHA23.57383676
3TRIB33.38815943
4EEF2K3.01068292
5WEE12.76358119
6SMG12.73726602
7MKNK12.73693177
8ICK2.67160052
9BUB12.65945053
10CDC72.64080439
11SRPK12.54135042
12AKT32.42315487
13MKNK22.41981188
14LATS12.35483405
15STK38L2.23465546
16MAP3K102.17178076
17PLK32.03586456
18RIPK12.00749856
19NTRK11.96705121
20PASK1.92968558
21TTK1.92035728
22TSSK61.91536277
23ERBB31.91431612
24IRAK31.90697405
25SIK11.88763229
26PDGFRA1.84235916
27DDR21.82931749
28ZAK1.81533404
29BRD41.81419928
30CDK71.79175424
31RPS6KB21.68853981
32BRSK21.57997471
33PLK11.55675225
34TTN1.52775799
35FGFR41.51728703
36MST1R1.44961325
37PRPF4B1.44138891
38BCR1.41781884
39ATR1.41385815
40AURKB1.33519456
41YES11.32695818
42CHEK11.28350998
43STK31.27324663
44CHEK21.27239711
45NEK21.26823735
46NEK11.23629922
47MAP3K91.22350248
48PLK41.21964125
49LATS21.19095496
50MET1.12973571
51CAMK1G1.12733423
52FRK1.12640591
53EIF2AK11.12198676
54ATM1.07999427
55NEK61.06127097
56STK101.03242008
57PLK21.00877505
58KSR20.99859298
59EIF2AK30.96258350
60CAMK1D0.93762137
61CHUK0.93462660
62STK240.93095621
63NEK90.92927287
64CDK20.92757988
65PAK40.91983965
66AURKA0.89988676
67FLT30.89621057
68TESK10.89294134
69MAP3K80.89101420
70TYRO30.88758520
71VRK10.87220238
72CDK60.85910292
73TGFBR10.85901958
74ERBB40.84559260
75PTK60.83245854
76MUSK0.82531841
77MOS0.81629135
78NME20.81455774
79MTOR0.80589872
80TAOK20.80562662
81FGFR10.77739844
82DMPK0.77376692
83STK40.76550968
84CLK10.76439168
85CDK10.76131715
86EIF2AK20.75195011
87ARAF0.74665330
88PBK0.73232020
89BMX0.72157089
90LIMK10.70391465
91ALK0.70115792
92CDK90.68533653
93KSR10.67940277
94MELK0.67211012
95CDK40.66943833
96SCYL20.66870651
97TRPM70.63505954
98PRKD30.62491371
99PIM10.62099790
100PRKCI0.61877609
101PNCK0.61476834
102BRAF0.56560657
103MST40.55925435
104CSNK1D0.55576257
105SIK30.54766471
106MAPK100.54074192
107TAF10.53618027
108RET0.52943280
109PTK20.52646632
110PRKDC0.51718355
111BRSK10.51672316
112ROCK20.51426548
113RPS6KA40.50834001
114MAPK140.50067439
115PDGFRB0.49662169
116AKT10.49645546
117PAK20.48640537
118CSNK2A20.48356073
119TESK20.48129948
120CDK80.47950414
121TLK10.47831719
122CDK150.46504725
123MAP3K130.46353850
124CSNK2A10.45552741
125MAPK10.45276279
126CDK180.45049571
127RPS6KA20.44024439
128CDK11A0.43804533
129CSNK1E0.43407505
130MAP3K140.43365614
131FER0.41249027
132ERN10.41220614
133NUAK10.41092905
134ACVR1B0.40019887
135EPHB20.39628876
136AKT20.39347462
137GSK3B0.39321536
138CDK140.37846330
139RPS6KB10.36776479
140EPHB10.35320959
141PKN20.34298514
142PAK10.33641517

Predicted pathways (KEGG)

RankGene SetZ-score
1Mismatch repair_Homo sapiens_hsa034303.72267635
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.58130355
3DNA replication_Homo sapiens_hsa030303.35428236
4Spliceosome_Homo sapiens_hsa030403.01498566
5One carbon pool by folate_Homo sapiens_hsa006702.97550423
6RNA transport_Homo sapiens_hsa030132.90496609
7Non-homologous end-joining_Homo sapiens_hsa034502.84071674
8Cell cycle_Homo sapiens_hsa041102.70461221
9Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.51967376
10Nucleotide excision repair_Homo sapiens_hsa034202.37492460
11Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.36970175
12Homologous recombination_Homo sapiens_hsa034402.33192320
13mRNA surveillance pathway_Homo sapiens_hsa030152.19703939
14RNA degradation_Homo sapiens_hsa030182.10212948
15Fanconi anemia pathway_Homo sapiens_hsa034602.08378242
16RNA polymerase_Homo sapiens_hsa030202.00906356
17p53 signaling pathway_Homo sapiens_hsa041151.92083611
18Base excision repair_Homo sapiens_hsa034101.91969183
19Basal transcription factors_Homo sapiens_hsa030221.85437514
20Hippo signaling pathway_Homo sapiens_hsa043901.76482502
21Basal cell carcinoma_Homo sapiens_hsa052171.75517999
22Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.73856324
23MicroRNAs in cancer_Homo sapiens_hsa052061.62793922
24Prion diseases_Homo sapiens_hsa050201.60469877
25Proteasome_Homo sapiens_hsa030501.57193860
26Adherens junction_Homo sapiens_hsa045201.51901794
27Renal cell carcinoma_Homo sapiens_hsa052111.50386532
28TGF-beta signaling pathway_Homo sapiens_hsa043501.49179211
29Hedgehog signaling pathway_Homo sapiens_hsa043401.46139169
30Small cell lung cancer_Homo sapiens_hsa052221.42148834
31Non-small cell lung cancer_Homo sapiens_hsa052231.33851672
32ECM-receptor interaction_Homo sapiens_hsa045121.33241102
33Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.26408542
34Notch signaling pathway_Homo sapiens_hsa043301.26395837
35Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.25772277
36Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.25594152
37Pentose phosphate pathway_Homo sapiens_hsa000301.21626339
38Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.19070677
39Pyrimidine metabolism_Homo sapiens_hsa002401.18058095
40Viral carcinogenesis_Homo sapiens_hsa052031.17385858
41ErbB signaling pathway_Homo sapiens_hsa040121.15713546
42Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.14781051
43Tight junction_Homo sapiens_hsa045301.12567819
44Thyroid cancer_Homo sapiens_hsa052161.09879707
45Melanoma_Homo sapiens_hsa052181.06979343
46Systemic lupus erythematosus_Homo sapiens_hsa053221.06561732
47Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.05694312
48Insulin signaling pathway_Homo sapiens_hsa049101.05455178
49Prostate cancer_Homo sapiens_hsa052151.03284253
50Selenocompound metabolism_Homo sapiens_hsa004501.01301090
51HTLV-I infection_Homo sapiens_hsa051660.99603298
52Proteoglycans in cancer_Homo sapiens_hsa052050.99456727
53Acute myeloid leukemia_Homo sapiens_hsa052210.98025149
54Bladder cancer_Homo sapiens_hsa052190.97369064
55VEGF signaling pathway_Homo sapiens_hsa043700.96900346
56Transcriptional misregulation in cancer_Homo sapiens_hsa052020.96661145
57Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.95659072
58Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.95195462
59Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.94943700
60Neurotrophin signaling pathway_Homo sapiens_hsa047220.94139900
61Epstein-Barr virus infection_Homo sapiens_hsa051690.93626485
62Carbon metabolism_Homo sapiens_hsa012000.92203983
63AMPK signaling pathway_Homo sapiens_hsa041520.89818099
64Focal adhesion_Homo sapiens_hsa045100.89788146
65Longevity regulating pathway - mammal_Homo sapiens_hsa042110.89467718
66Legionellosis_Homo sapiens_hsa051340.85459978
67Pathways in cancer_Homo sapiens_hsa052000.83146820
68PI3K-Akt signaling pathway_Homo sapiens_hsa041510.81865668
69Wnt signaling pathway_Homo sapiens_hsa043100.81155672
70Estrogen signaling pathway_Homo sapiens_hsa049150.81000811
71Herpes simplex infection_Homo sapiens_hsa051680.79929885
72Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.78915609
73Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.76730482
74Melanogenesis_Homo sapiens_hsa049160.72493136
75Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.72371056
762-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.71331782
77Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.71090586
78Fructose and mannose metabolism_Homo sapiens_hsa000510.69499176
79Gap junction_Homo sapiens_hsa045400.69080870
80Steroid biosynthesis_Homo sapiens_hsa001000.68494293
81Central carbon metabolism in cancer_Homo sapiens_hsa052300.68339085
82Antigen processing and presentation_Homo sapiens_hsa046120.67399449
83Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.67155955
84Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.66928614
85Long-term potentiation_Homo sapiens_hsa047200.66730794
86Thyroid hormone synthesis_Homo sapiens_hsa049180.66522606
87Prolactin signaling pathway_Homo sapiens_hsa049170.66138715
88Vitamin B6 metabolism_Homo sapiens_hsa007500.65537750
89Colorectal cancer_Homo sapiens_hsa052100.64540398
90Dilated cardiomyopathy_Homo sapiens_hsa054140.63992067
91Endometrial cancer_Homo sapiens_hsa052130.61252697
92Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.61116631
93Oocyte meiosis_Homo sapiens_hsa041140.61101987
94Regulation of actin cytoskeleton_Homo sapiens_hsa048100.60531628
95Chronic myeloid leukemia_Homo sapiens_hsa052200.60228024
96Inositol phosphate metabolism_Homo sapiens_hsa005620.59837330
97Other glycan degradation_Homo sapiens_hsa005110.59809528
98Choline metabolism in cancer_Homo sapiens_hsa052310.59707182
99Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.59194670
100Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.58410259
101Pyruvate metabolism_Homo sapiens_hsa006200.56301229
102N-Glycan biosynthesis_Homo sapiens_hsa005100.56183769
103Glucagon signaling pathway_Homo sapiens_hsa049220.54272169
104Phospholipase D signaling pathway_Homo sapiens_hsa040720.53922673
105Purine metabolism_Homo sapiens_hsa002300.53609247
106Protein export_Homo sapiens_hsa030600.53130753
107GnRH signaling pathway_Homo sapiens_hsa049120.52811293
108Apoptosis_Homo sapiens_hsa042100.52581761
109Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.50273829
110Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.50207256
111Thyroid hormone signaling pathway_Homo sapiens_hsa049190.47270590
112Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.46104642
113Alcoholism_Homo sapiens_hsa050340.42503755
114mTOR signaling pathway_Homo sapiens_hsa041500.41638437
115Hepatitis B_Homo sapiens_hsa051610.40379663
116NF-kappa B signaling pathway_Homo sapiens_hsa040640.40008587
117Protein digestion and absorption_Homo sapiens_hsa049740.39755875
118Viral myocarditis_Homo sapiens_hsa054160.38204155
119Leukocyte transendothelial migration_Homo sapiens_hsa046700.37652778
120Lysine degradation_Homo sapiens_hsa003100.37042641
121FoxO signaling pathway_Homo sapiens_hsa040680.30862312
122Shigellosis_Homo sapiens_hsa051310.30003323
123Arachidonic acid metabolism_Homo sapiens_hsa005900.28894273
124Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.28686010
125Rap1 signaling pathway_Homo sapiens_hsa040150.28022689
126HIF-1 signaling pathway_Homo sapiens_hsa040660.27703551
127Glioma_Homo sapiens_hsa052140.27470306
128Folate biosynthesis_Homo sapiens_hsa007900.27190667
129Measles_Homo sapiens_hsa051620.27060314
130AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.26661070
131Axon guidance_Homo sapiens_hsa043600.26540483
132Biosynthesis of amino acids_Homo sapiens_hsa012300.26257399
133Ribosome_Homo sapiens_hsa030100.25873258
134Amoebiasis_Homo sapiens_hsa051460.23805205
135Glutathione metabolism_Homo sapiens_hsa004800.23336337
136Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.22029851
137Pancreatic cancer_Homo sapiens_hsa052120.21909845
138Galactose metabolism_Homo sapiens_hsa000520.21377217
139Fatty acid biosynthesis_Homo sapiens_hsa000610.21087972

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »