FUT11

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axon ensheathment in central nervous system (GO:0032291)7.42181835
2central nervous system myelination (GO:0022010)7.42181835
3behavioral response to nicotine (GO:0035095)6.44032939
4fatty acid elongation (GO:0030497)5.41929387
5neuron cell-cell adhesion (GO:0007158)4.82927165
6cellular response to ATP (GO:0071318)4.66884182
7myelination (GO:0042552)4.66627489
8axon ensheathment (GO:0008366)4.58982116
9ensheathment of neurons (GO:0007272)4.58982116
10response to pheromone (GO:0019236)4.11349253
11presynaptic membrane organization (GO:0097090)4.08569693
12positive regulation of uterine smooth muscle contraction (GO:0070474)4.00600476
13protein K11-linked deubiquitination (GO:0035871)3.86974623
14RNA destabilization (GO:0050779)3.80322305
15axonal fasciculation (GO:0007413)3.73125140
16cell proliferation in forebrain (GO:0021846)3.68792512
17presynaptic membrane assembly (GO:0097105)3.68217337
18neuron recognition (GO:0008038)3.64408558
19negative regulation of mast cell activation (GO:0033004)3.61037761
20L-fucose catabolic process (GO:0042355)3.55343220
21fucose catabolic process (GO:0019317)3.55343220
22L-fucose metabolic process (GO:0042354)3.55343220
23tolerance induction (GO:0002507)3.54230212
24positive regulation of prostaglandin secretion (GO:0032308)3.52466427
25long-chain fatty acid biosynthetic process (GO:0042759)3.51361912
26dendritic spine morphogenesis (GO:0060997)3.51090341
27neuron remodeling (GO:0016322)3.45157915
28negative regulation of axon extension (GO:0030517)3.42276354
29dendrite morphogenesis (GO:0048813)3.41752867
30establishment of mitochondrion localization (GO:0051654)3.41632192
31detection of light stimulus involved in sensory perception (GO:0050962)3.38469218
32detection of light stimulus involved in visual perception (GO:0050908)3.38469218
33positive regulation of oligodendrocyte differentiation (GO:0048714)3.37546431
34regulation of collateral sprouting (GO:0048670)3.33787232
35epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.29934225
36limb bud formation (GO:0060174)3.26067143
37negative regulation of axonogenesis (GO:0050771)3.22800853
38substantia nigra development (GO:0021762)3.19850735
39peptidyl-tyrosine autophosphorylation (GO:0038083)3.18510218
40oligodendrocyte differentiation (GO:0048709)3.17954425
41eye photoreceptor cell differentiation (GO:0001754)3.15657267
42photoreceptor cell differentiation (GO:0046530)3.15657267
43negative regulation of neurotransmitter transport (GO:0051589)3.09849819
44adhesion of symbiont to host cell (GO:0044650)3.09623572
45virion attachment to host cell (GO:0019062)3.09623572
46nephron epithelium morphogenesis (GO:0072088)3.07816918
47nephron tubule morphogenesis (GO:0072078)3.07816918
48epithelial cilium movement (GO:0003351)3.06002426
49response to methylmercury (GO:0051597)3.05624085
50cerebral cortex radially oriented cell migration (GO:0021799)3.05091272
51transmission of nerve impulse (GO:0019226)2.98696502
52detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.94860762
53endoderm formation (GO:0001706)2.92168192
54axon development (GO:0061564)2.90464480
55negative regulation of telomere maintenance (GO:0032205)2.90218063
56zinc ion homeostasis (GO:0055069)2.89518233
57positive regulation of synapse assembly (GO:0051965)2.89033872
58photoreceptor cell development (GO:0042461)2.88824759
59mating behavior (GO:0007617)2.87263479
60cAMP catabolic process (GO:0006198)2.86793237
61neuronal action potential propagation (GO:0019227)2.86318906
62negative regulation of axon guidance (GO:1902668)2.85721425
63response to lipoprotein particle (GO:0055094)2.83506844
64kidney morphogenesis (GO:0060993)2.83500379
65astrocyte development (GO:0014002)2.82422819
66negative regulation of neurotransmitter secretion (GO:0046929)2.82402193
67regulation of uterine smooth muscle contraction (GO:0070472)2.81590012
68cholesterol biosynthetic process (GO:0006695)2.81444250
69positive regulation of defense response to virus by host (GO:0002230)2.79778964
70regulation of prostaglandin secretion (GO:0032306)2.77958561
71cilium morphogenesis (GO:0060271)2.77592414
72cellular ketone body metabolic process (GO:0046950)2.77552651
73protein palmitoylation (GO:0018345)2.76947612
74mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.75485772
75detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.74696459
76detection of temperature stimulus involved in sensory perception (GO:0050961)2.74696459
77regulation of cilium movement (GO:0003352)2.74277009
78preassembly of GPI anchor in ER membrane (GO:0016254)2.74237241
79sequestering of extracellular ligand from receptor (GO:0035581)2.73942207
80regulation of hippo signaling (GO:0035330)2.73421358
81neural tube formation (GO:0001841)2.72715638
82indole-containing compound catabolic process (GO:0042436)2.72306502
83indolalkylamine catabolic process (GO:0046218)2.72306502
84tryptophan catabolic process (GO:0006569)2.72306502
85multicellular organism reproduction (GO:0032504)2.72299147
86positive regulation of fatty acid transport (GO:2000193)2.72209170
87myelination in peripheral nervous system (GO:0022011)2.70150530
88peripheral nervous system axon ensheathment (GO:0032292)2.70150530
89magnesium ion transport (GO:0015693)2.69532504
90eye photoreceptor cell development (GO:0042462)2.69355947
91negative regulation of protein localization to cell surface (GO:2000009)2.68789688
92activated T cell proliferation (GO:0050798)2.68238607
93renal tubule morphogenesis (GO:0061333)2.67695523
94cranial nerve morphogenesis (GO:0021602)2.66838701
95indolalkylamine metabolic process (GO:0006586)2.66809923
96positive regulation of mitochondrial fission (GO:0090141)2.66730914
97regulation of neuron projection regeneration (GO:0070570)2.66588243
98regulation of axon regeneration (GO:0048679)2.66588243
99cell migration in hindbrain (GO:0021535)2.66572907
100protein localization to cilium (GO:0061512)2.66386710
101adult walking behavior (GO:0007628)2.65927951
102nerve growth factor signaling pathway (GO:0038180)2.65534077
103lysosome localization (GO:0032418)2.64707541
104negative regulation of cytosolic calcium ion concentration (GO:0051481)2.64001062
105negative regulation of macrophage differentiation (GO:0045650)2.63645893
106L-serine transport (GO:0015825)2.63623629
107pericardium development (GO:0060039)2.63119796
108retinal ganglion cell axon guidance (GO:0031290)2.62624629
109maternal behavior (GO:0042711)2.62129792
110regulation of axon guidance (GO:1902667)2.61762916
111neuron fate determination (GO:0048664)2.61464813
112membrane tubulation (GO:0097320)2.60309840
113substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.60146748
114substrate-independent telencephalic tangential migration (GO:0021826)2.60146748
115nonmotile primary cilium assembly (GO:0035058)2.59076597
116pyrimidine nucleobase catabolic process (GO:0006208)2.57445071
117layer formation in cerebral cortex (GO:0021819)2.57235072
118regulation of mesoderm development (GO:2000380)2.57108202
119regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)2.56986730
120regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.56703720
121mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.56023876
122interferon-gamma production (GO:0032609)2.55903371
123N-acetylglucosamine metabolic process (GO:0006044)2.55483869
124spinal cord motor neuron differentiation (GO:0021522)2.55202110
125glomerular filtration (GO:0003094)2.54807258
126mitotic cell cycle arrest (GO:0071850)2.54337089
127membrane assembly (GO:0071709)2.53055514
128blood vessel maturation (GO:0001955)2.52505359
129regulation of synapse structural plasticity (GO:0051823)2.52495918
130amyloid precursor protein metabolic process (GO:0042982)2.52276589
131gamma-aminobutyric acid signaling pathway (GO:0007214)2.52025826
132somite development (GO:0061053)2.51842289
133sterol biosynthetic process (GO:0016126)2.51146127
134positive regulation of sodium ion transmembrane transporter activity (GO:2000651)2.50682696
135endosome to melanosome transport (GO:0035646)2.50529248
136endosome to pigment granule transport (GO:0043485)2.50529248
137regulation of rhodopsin mediated signaling pathway (GO:0022400)2.50518329
138neural nucleus development (GO:0048857)2.50484536
139kynurenine metabolic process (GO:0070189)2.50277612
140protein K48-linked deubiquitination (GO:0071108)2.49448543
141protein localization to Golgi apparatus (GO:0034067)2.48969800
142negative regulation of transcription regulatory region DNA binding (GO:2000678)2.48333843
143positive regulation of icosanoid secretion (GO:0032305)2.47468196
144ketone body metabolic process (GO:1902224)2.46575687
145neuronal ion channel clustering (GO:0045161)2.46327033
146response to redox state (GO:0051775)2.46296073
147regulation of telomere maintenance (GO:0032204)2.45931742
148negative regulation of axon extension involved in axon guidance (GO:0048843)2.45576175
149establishment of protein localization to Golgi (GO:0072600)2.45516550
150synaptic vesicle exocytosis (GO:0016079)2.45399867
151positive regulation of action potential (GO:0045760)2.45391326
152neuronal action potential (GO:0019228)2.45388059
153protein localization to synapse (GO:0035418)2.45379304
154histone H2B ubiquitination (GO:0033523)2.45298989
155cyclic nucleotide catabolic process (GO:0009214)2.45132899
156lymphangiogenesis (GO:0001946)2.44516517
157purinergic nucleotide receptor signaling pathway (GO:0035590)2.44237062
158axoneme assembly (GO:0035082)2.43688577
159long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.43569284
160positive regulation of CREB transcription factor activity (GO:0032793)2.43470035
161cornea development in camera-type eye (GO:0061303)2.43394847
162phosphatidylinositol 3-kinase signaling (GO:0014065)2.43072301
163Rap protein signal transduction (GO:0032486)2.42957424
164mannosylation (GO:0097502)2.41917100
165photoreceptor cell maintenance (GO:0045494)2.40397103
166rhodopsin mediated signaling pathway (GO:0016056)2.40210049
167myelin maintenance (GO:0043217)2.39700888
168adhesion of symbiont to host (GO:0044406)2.39372351
169negative regulation of cell aging (GO:0090344)2.38904411
170rRNA catabolic process (GO:0016075)2.38159231
171synaptic transmission, cholinergic (GO:0007271)2.37331276
172negative regulation of systemic arterial blood pressure (GO:0003085)2.36366329
173positive regulation of smooth muscle contraction (GO:0045987)2.36097595
174appendage development (GO:0048736)2.35757367
175limb development (GO:0060173)2.35757367
176negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)2.35582929
177protein-cofactor linkage (GO:0018065)2.35387265
178positive regulation of gastrulation (GO:2000543)2.35306321
179chaperone-mediated protein transport (GO:0072321)2.35085014
180urinary tract smooth muscle contraction (GO:0014848)2.34752036
181regulation of axon extension involved in axon guidance (GO:0048841)2.34481297
182protein localization to endosome (GO:0036010)2.34029248
183peristalsis (GO:0030432)2.33525940
184smoothened signaling pathway (GO:0007224)2.32750238
185behavioral response to ethanol (GO:0048149)2.31631450
186regulation of dendrite morphogenesis (GO:0048814)2.30982129
187regulation of developmental pigmentation (GO:0048070)2.30718809
188regulation of extent of cell growth (GO:0061387)2.30462706
189positive regulation of heat generation (GO:0031652)2.30007542
190ATP synthesis coupled proton transport (GO:0015986)2.29636951
191energy coupled proton transport, down electrochemical gradient (GO:0015985)2.29636951
192positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.28571251
193long-chain fatty-acyl-CoA metabolic process (GO:0035336)2.27585217
194negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.26802910
195cellular response to monoamine stimulus (GO:0071868)2.25964114
196cellular response to catecholamine stimulus (GO:0071870)2.25964114
197negative regulation of neuron projection development (GO:0010977)2.25909151

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.58084200
2GBX2_23144817_ChIP-Seq_PC3_Human3.23496832
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.21528571
4TAF15_26573619_Chip-Seq_HEK293_Human3.10675397
5JARID2_20064375_ChIP-Seq_MESCs_Mouse3.09188955
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.03712289
7EED_16625203_ChIP-ChIP_MESCs_Mouse2.98166513
8SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.95991375
9EZH2_27304074_Chip-Seq_ESCs_Mouse2.95862952
10SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.79530914
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.69516164
12EZH2_18974828_ChIP-Seq_MESCs_Mouse2.69516164
13AR_21572438_ChIP-Seq_LNCaP_Human2.68442556
14JARID2_20075857_ChIP-Seq_MESCs_Mouse2.60515800
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.59836805
16SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.52331790
17PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.45388891
18MTF2_20144788_ChIP-Seq_MESCs_Mouse2.45239604
19WT1_19549856_ChIP-ChIP_CCG9911_Human2.42139251
20BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.35685660
21RNF2_16625203_ChIP-ChIP_MESCs_Mouse2.32801047
22SUZ12_27294783_Chip-Seq_ESCs_Mouse2.31032521
23EZH2_27294783_Chip-Seq_ESCs_Mouse2.28136479
24CBX2_27304074_Chip-Seq_ESCs_Mouse2.25289330
25SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.19268178
26RNF2_27304074_Chip-Seq_ESCs_Mouse2.14416399
27STAT6_21828071_ChIP-Seq_BEAS2B_Human2.10704971
28SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.04565088
29BMI1_23680149_ChIP-Seq_NPCS_Mouse1.94776653
30OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.94478254
31CTBP1_25329375_ChIP-Seq_LNCAP_Human1.89936866
32PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.88728959
33ER_23166858_ChIP-Seq_MCF-7_Human1.84804805
34ZFP57_27257070_Chip-Seq_ESCs_Mouse1.84519106
35FLI1_27457419_Chip-Seq_LIVER_Mouse1.83507019
36CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.81531882
37CTBP2_25329375_ChIP-Seq_LNCAP_Human1.79842706
38IGF1R_20145208_ChIP-Seq_DFB_Human1.76754702
39SALL1_21062744_ChIP-ChIP_HESCs_Human1.74150063
40VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.69962881
41IRF1_19129219_ChIP-ChIP_H3396_Human1.68901850
42E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.64694967
43STAT3_23295773_ChIP-Seq_U87_Human1.63966361
44PCGF2_27294783_Chip-Seq_ESCs_Mouse1.63727578
45EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.60255386
46* HIF1A_21447827_ChIP-Seq_MCF-7_Human1.59505089
47POU3F2_20337985_ChIP-ChIP_501MEL_Human1.58955045
48P300_19829295_ChIP-Seq_ESCs_Human1.58814516
49TP63_19390658_ChIP-ChIP_HaCaT_Human1.58392273
50CDX2_19796622_ChIP-Seq_MESCs_Mouse1.57589688
51MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.56905054
52NOTCH1_21737748_ChIP-Seq_TLL_Human1.54549959
53DROSHA_22980978_ChIP-Seq_HELA_Human1.53607210
54SMAD3_21741376_ChIP-Seq_EPCs_Human1.53195583
55FUS_26573619_Chip-Seq_HEK293_Human1.52654399
56NR3C1_21868756_ChIP-Seq_MCF10A_Human1.50039063
57SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.47472581
58BCAT_22108803_ChIP-Seq_LS180_Human1.45201756
59TRIM28_21343339_ChIP-Seq_HEK293_Human1.45168838
60PIAS1_25552417_ChIP-Seq_VCAP_Human1.45059532
61EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.44902542
62TP53_22573176_ChIP-Seq_HFKS_Human1.44725518
63TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.42700564
64POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.42700564
65EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.42523835
66RNF2_27304074_Chip-Seq_NSC_Mouse1.40977044
67RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.40307388
68EP300_21415370_ChIP-Seq_HL-1_Mouse1.38362557
69FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.37853508
70HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.37197063
71VDR_22108803_ChIP-Seq_LS180_Human1.35059787
72TCF4_23295773_ChIP-Seq_U87_Human1.34883294
73EWS_26573619_Chip-Seq_HEK293_Human1.34751581
74PCGF2_27294783_Chip-Seq_NPCs_Mouse1.32582815
75CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.32468591
76ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.31711048
77GATA3_21878914_ChIP-Seq_MCF-7_Human1.30174611
78RING1B_27294783_Chip-Seq_ESCs_Mouse1.29860600
79MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.28340279
80FOXA1_27270436_Chip-Seq_PROSTATE_Human1.28340051
81FOXA1_25329375_ChIP-Seq_VCAP_Human1.28340051
82RING1B_27294783_Chip-Seq_NPCs_Mouse1.28150787
83MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.27391859
84SMAD4_21741376_ChIP-Seq_EPCs_Human1.25935616
85TOP2B_26459242_ChIP-Seq_MCF-7_Human1.22386290
86NANOG_19829295_ChIP-Seq_ESCs_Human1.22280849
87SOX2_19829295_ChIP-Seq_ESCs_Human1.22280849
88HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.22053272
89SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.21886277
90UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.21008966
91CBP_20019798_ChIP-Seq_JUKART_Human1.20734753
92IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.20734753
93REST_21632747_ChIP-Seq_MESCs_Mouse1.19942576
94PRDM14_20953172_ChIP-Seq_ESCs_Human1.18187866
95TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17997570
96NR3C1_23031785_ChIP-Seq_PC12_Mouse1.17840120
97TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.17212527
98TP53_18474530_ChIP-ChIP_U2OS_Human1.13522144
99IKZF1_21737484_ChIP-ChIP_HCT116_Human1.13263617
100SUZ12_27294783_Chip-Seq_NPCs_Mouse1.12612263
101WT1_25993318_ChIP-Seq_PODOCYTE_Human1.12566144
102FLI1_21867929_ChIP-Seq_TH2_Mouse1.10820618
103SMAD4_21799915_ChIP-Seq_A2780_Human1.10395705
104ETV2_25802403_ChIP-Seq_MESCs_Mouse1.10108931
105NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.09792410
106NRF2_20460467_ChIP-Seq_MEFs_Mouse1.09792410
107RXR_22108803_ChIP-Seq_LS180_Human1.09397679
108ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.09118570
109RUNX2_22187159_ChIP-Seq_PCA_Human1.06647098
110OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.06536343
111CJUN_26792858_Chip-Seq_BT549_Human1.05280294
112AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.04789352
113LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03321340
114REST_18959480_ChIP-ChIP_MESCs_Mouse1.03261099
115WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.02885614
116SMAD_19615063_ChIP-ChIP_OVARY_Human1.02885525
117STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.02069674
118TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.01775401
119P53_22127205_ChIP-Seq_FIBROBLAST_Human1.01736321
120ZNF274_21170338_ChIP-Seq_K562_Hela1.00822060
121ZNF217_24962896_ChIP-Seq_MCF-7_Human1.00803736
122SOX2_21211035_ChIP-Seq_LN229_Gbm1.00726539
123EZH2_27294783_Chip-Seq_NPCs_Mouse0.99762272
124TCF4_22108803_ChIP-Seq_LS180_Human0.99354072
125* TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.98955643
126* FOXA1_21572438_ChIP-Seq_LNCaP_Human0.98942137
127NFE2_27457419_Chip-Seq_LIVER_Mouse0.96851112
128TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.96715571
129TP53_16413492_ChIP-PET_HCT116_Human0.96328329
130SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.95638366
131POU5F1_16153702_ChIP-ChIP_HESCs_Human0.95569955
132NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.94453569
133JUN_21703547_ChIP-Seq_K562_Human0.94059651
134HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.93194414
135AR_25329375_ChIP-Seq_VCAP_Human0.92234822
136FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.92081876
137GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91441105
138MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.91064546
139KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.88652649
140EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.88502091
141TP53_20018659_ChIP-ChIP_R1E_Mouse0.86743862
142RARB_27405468_Chip-Seq_BRAIN_Mouse0.86275525
143KDM2B_26808549_Chip-Seq_REH_Human0.85708594
144NANOG_18555785_Chip-Seq_ESCs_Mouse0.84770948
145GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.84066635
146GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.83253915

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation4.17051437
2MP0003880_abnormal_central_pattern4.01270821
3MP0000920_abnormal_myelination3.46831138
4MP0005174_abnormal_tail_pigmentation3.08538663
5MP0001529_abnormal_vocalization2.86224989
6MP0000778_abnormal_nervous_system2.76467660
7MP0004270_analgesia2.67765943
8MP0000537_abnormal_urethra_morphology2.36425190
9MP0001905_abnormal_dopamine_level2.31929444
10MP0002837_dystrophic_cardiac_calcinosis2.25673711
11MP0005423_abnormal_somatic_nervous2.25578484
12MP0003011_delayed_dark_adaptation2.25504432
13MP0005623_abnormal_meninges_morphology2.21227135
14MP0004859_abnormal_synaptic_plasticity2.16824707
15MP0008438_abnormal_cutaneous_collagen2.16422071
16MP0009379_abnormal_foot_pigmentation2.11673641
17MP0003635_abnormal_synaptic_transmissio2.07382202
18MP0005075_abnormal_melanosome_morpholog2.05708853
19MP0004742_abnormal_vestibular_system2.05024470
20MP0002734_abnormal_mechanical_nocicepti2.02927043
21MP0002735_abnormal_chemical_nociception2.00712132
22MP0001486_abnormal_startle_reflex1.98646064
23MP0003195_calcinosis1.98023952
24MP0002938_white_spotting1.95098666
25MP0005408_hypopigmentation1.93036945
26MP0003329_amyloid_beta_deposits1.91693108
27MP0002272_abnormal_nervous_system1.90557164
28MP0002638_abnormal_pupillary_reflex1.90287394
29MP0003634_abnormal_glial_cell1.87298068
30MP0000015_abnormal_ear_pigmentation1.85528124
31MP0002064_seizures1.84127034
32MP0005084_abnormal_gallbladder_morpholo1.83448311
33MP0005409_darkened_coat_color1.82490502
34MP0010386_abnormal_urinary_bladder1.81258906
35MP0006276_abnormal_autonomic_nervous1.80277945
36MP0001324_abnormal_eye_pigmentation1.78712804
37MP0009046_muscle_twitch1.76976934
38MP0009384_cardiac_valve_regurgitation1.76577579
39MP0000371_diluted_coat_color1.75631108
40MP0004133_heterotaxia1.75559913
41MP0003690_abnormal_glial_cell1.74544240
42MP0000462_abnormal_digestive_system1.70347428
43MP0005171_absent_coat_pigmentation1.69509183
44MP0005551_abnormal_eye_electrophysiolog1.69096809
45MP0002928_abnormal_bile_duct1.68890625
46MP0002653_abnormal_ependyma_morphology1.68883249
47MP0001986_abnormal_taste_sensitivity1.68344238
48MP0002184_abnormal_innervation1.67513204
49MP0001968_abnormal_touch/_nociception1.66529996
50MP0009745_abnormal_behavioral_response1.66239403
51MP0004142_abnormal_muscle_tone1.64523032
52MP0002572_abnormal_emotion/affect_behav1.62116361
53MP0006292_abnormal_olfactory_placode1.61949840
54MP0004272_abnormal_basement_membrane1.60746956
55MP0001984_abnormal_olfaction1.60182238
56MP0000955_abnormal_spinal_cord1.55903096
57MP0003646_muscle_fatigue1.55633465
58MP0004134_abnormal_chest_morphology1.52962010
59MP0002063_abnormal_learning/memory/cond1.51802224
60MP0001970_abnormal_pain_threshold1.49705259
61MP0001919_abnormal_reproductive_system1.47622493
62MP0008875_abnormal_xenobiotic_pharmacok1.46723087
63MP0003890_abnormal_embryonic-extraembry1.46081473
64MP0005167_abnormal_blood-brain_barrier1.46077640
65MP0002882_abnormal_neuron_morphology1.44154867
66MP0002067_abnormal_sensory_capabilities1.38438817
67MP0008877_abnormal_DNA_methylation1.37852950
68MP0006072_abnormal_retinal_apoptosis1.37426372
69MP0001502_abnormal_circadian_rhythm1.35602864
70MP0003122_maternal_imprinting1.35334346
71MP0005645_abnormal_hypothalamus_physiol1.34984163
72MP0001727_abnormal_embryo_implantation1.34776734
73MP0003632_abnormal_nervous_system1.32587724
74MP0004484_altered_response_of1.26757986
75MP0002909_abnormal_adrenal_gland1.24000428
76MP0005389_reproductive_system_phenotype1.22811490
77MP0004885_abnormal_endolymph1.22119830
78MP0000647_abnormal_sebaceous_gland1.21734210
79MP0002295_abnormal_pulmonary_circulatio1.21431607
80MP0002102_abnormal_ear_morphology1.20886379
81MP0003136_yellow_coat_color1.20317500
82MP0001299_abnormal_eye_distance/1.19780863
83MP0004147_increased_porphyrin_level1.19324480
84MP0005410_abnormal_fertilization1.17859714
85MP0000631_abnormal_neuroendocrine_gland1.17407210
86MP0002752_abnormal_somatic_nervous1.16772476
87MP0004130_abnormal_muscle_cell1.16508781
88MP0002733_abnormal_thermal_nociception1.15479861
89MP0001851_eye_inflammation1.14872229
90MP0003937_abnormal_limbs/digits/tail_de1.14636228
91MP0005391_vision/eye_phenotype1.12934664
92MP0002090_abnormal_vision1.11822137
93MP0008872_abnormal_physiological_respon1.10994097
94MP0003950_abnormal_plasma_membrane1.10973659
95MP0005195_abnormal_posterior_eye1.10414905
96MP0002876_abnormal_thyroid_physiology1.10171428
97MP0000013_abnormal_adipose_tissue1.09915056
98MP0005197_abnormal_uvea_morphology1.09878147
99MP0008775_abnormal_heart_ventricle1.09257023
100MP0002736_abnormal_nociception_after1.08660075
101MP0002152_abnormal_brain_morphology1.08367341
102MP0000372_irregular_coat_pigmentation1.07859767
103MP0003283_abnormal_digestive_organ1.07579345
104MP0002229_neurodegeneration1.07419488
105MP0001293_anophthalmia1.06540646
106MP0000427_abnormal_hair_cycle1.04694720
107MP0000534_abnormal_ureter_morphology1.04432083
108MP0005386_behavior/neurological_phenoty1.04309777
109MP0004924_abnormal_behavior1.04309777
110MP0003385_abnormal_body_wall1.02895409
111MP0000604_amyloidosis1.01606060
112MP0004215_abnormal_myocardial_fiber1.01185702
113MP0002095_abnormal_skin_pigmentation1.01129434
114MP0001879_abnormal_lymphatic_vessel1.00928742
115MP0002557_abnormal_social/conspecific_i1.00859232
116MP0002160_abnormal_reproductive_system1.00563905
117MP0005253_abnormal_eye_physiology1.00542690
118MP0008569_lethality_at_weaning1.00163878
119MP0003942_abnormal_urinary_system0.98711394
120MP0002066_abnormal_motor_capabilities/c0.98324125
121MP0000465_gastrointestinal_hemorrhage0.98140019
122MP0002075_abnormal_coat/hair_pigmentati0.97773762
123MP0009697_abnormal_copulation0.92937882
124MP0001188_hyperpigmentation0.92536141
125MP0001346_abnormal_lacrimal_gland0.92418436
126MP0000049_abnormal_middle_ear0.92059599
127MP0006054_spinal_hemorrhage0.89618845
128MP0001440_abnormal_grooming_behavior0.89189669
129MP0000767_abnormal_smooth_muscle0.88339012
130MP0000230_abnormal_systemic_arterial0.88180895
131MP0004084_abnormal_cardiac_muscle0.86599704
132MP0001485_abnormal_pinna_reflex0.86277661
133MP0004811_abnormal_neuron_physiology0.84921474
134MP0003861_abnormal_nervous_system0.83389780
135MP0001958_emphysema0.82808112
136MP0010678_abnormal_skin_adnexa0.82750211
137MP0004085_abnormal_heartbeat0.81206995
138MP0005595_abnormal_vascular_smooth0.80626182
139MP0003631_nervous_system_phenotype0.79816722
140MP0000026_abnormal_inner_ear0.78404635
141MP0001963_abnormal_hearing_physiology0.75057179
142MP0008789_abnormal_olfactory_epithelium0.74792557
143MP0002751_abnormal_autonomic_nervous0.74403429
144MP0004381_abnormal_hair_follicle0.74329999
145MP0000566_synostosis0.74170256
146MP0001943_abnormal_respiration0.71625753
147MP0005503_abnormal_tendon_morphology0.71318175
148MP0009250_abnormal_appendicular_skeleto0.71146893
149MP0004145_abnormal_muscle_electrophysio0.71114661
150MP0001340_abnormal_eyelid_morphology0.70085484
151MP0000538_abnormal_urinary_bladder0.69892673
152MP0003137_abnormal_impulse_conducting0.67743049
153MP0002282_abnormal_trachea_morphology0.65622633

Predicted human phenotypes

RankGene SetZ-score
1Neurofibrillary tangles (HP:0002185)5.56632884
2Congenital stationary night blindness (HP:0007642)4.50771100
3Parakeratosis (HP:0001036)4.30586496
4Degeneration of the lateral corticospinal tracts (HP:0002314)4.29404559
5Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)4.29404559
6Cerebral inclusion bodies (HP:0100314)4.22671909
7Molar tooth sign on MRI (HP:0002419)3.72008399
8Abnormality of midbrain morphology (HP:0002418)3.72008399
9Retinal dysplasia (HP:0007973)3.66593496
10Nephronophthisis (HP:0000090)3.60607509
11Pancreatic cysts (HP:0001737)3.58007561
12B lymphocytopenia (HP:0010976)3.56190131
13Abnormality of B cell number (HP:0010975)3.46553681
14Pancreatic fibrosis (HP:0100732)3.42883071
15Abnormality of the corticospinal tract (HP:0002492)3.42170285
16Megalencephaly (HP:0001355)3.37118877
17Cerebellar dysplasia (HP:0007033)3.37038770
18Sensory axonal neuropathy (HP:0003390)3.32541144
19Adactyly (HP:0009776)3.18359450
20Abnormality of the renal medulla (HP:0100957)3.07908167
21Stridor (HP:0010307)3.02326753
22Supranuclear gaze palsy (HP:0000605)3.00135275
23Oligodactyly (hands) (HP:0001180)2.98680900
24Myokymia (HP:0002411)2.93265353
25Decreased central vision (HP:0007663)2.91086397
26Fibular aplasia (HP:0002990)2.90838991
27Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.86988796
28Mesangial abnormality (HP:0001966)2.85803651
29True hermaphroditism (HP:0010459)2.84017345
30Abnormal drinking behavior (HP:0030082)2.81942485
31Polydipsia (HP:0001959)2.81942485
32Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.81524754
33Patellar aplasia (HP:0006443)2.81123911
34Tubular atrophy (HP:0000092)2.80840142
35Chronic hepatic failure (HP:0100626)2.76370730
36Vascular tortuosity (HP:0004948)2.74294119
37Premature skin wrinkling (HP:0100678)2.71934415
38Abnormality of alanine metabolism (HP:0010916)2.68229546
39Hyperalaninemia (HP:0003348)2.68229546
40Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.68229546
41Arterial tortuosity (HP:0005116)2.67443036
42Aplasia/Hypoplasia of the patella (HP:0006498)2.62344502
43Partial agenesis of the corpus callosum (HP:0001338)2.61428531
44Rib fusion (HP:0000902)2.61424871
45Abnormality of the pons (HP:0007361)2.60383553
46Aplasia/hypoplasia of the uterus (HP:0008684)2.59106891
47Absent septum pellucidum (HP:0001331)2.58699923
48Chin dimple (HP:0010751)2.57103050
49Abnormal rod and cone electroretinograms (HP:0008323)2.55879374
50Albinism (HP:0001022)2.55373624
51Hypoplasia of the pons (HP:0012110)2.50940010
52Chorioretinal atrophy (HP:0000533)2.48744371
53Medial flaring of the eyebrow (HP:0010747)2.48490480
54Limb dystonia (HP:0002451)2.47618446
55Buphthalmos (HP:0000557)2.44344942
56Synostosis involving the elbow (HP:0003938)2.42882611
57Humeroradial synostosis (HP:0003041)2.42882611
58Polyphagia (HP:0002591)2.41090577
59Congenital sensorineural hearing impairment (HP:0008527)2.40897338
60Hypoplastic iliac wings (HP:0002866)2.39127750
61Insidious onset (HP:0003587)2.38165926
62Termporal pattern (HP:0011008)2.38165926
63Inability to walk (HP:0002540)2.36130267
64Severe visual impairment (HP:0001141)2.34295930
65Abnormality of the renal cortex (HP:0011035)2.34093213
66Renal Fanconi syndrome (HP:0001994)2.32867753
67Chronic otitis media (HP:0000389)2.32111225
68Mutism (HP:0002300)2.32065921
69Akinesia (HP:0002304)2.31525578
70Pendular nystagmus (HP:0012043)2.30877134
71Dysmetria (HP:0001310)2.30182730
72Spastic gait (HP:0002064)2.29504236
73Increased hepatocellular lipid droplets (HP:0006565)2.27861848
74Septo-optic dysplasia (HP:0100842)2.27235781
75Scanning speech (HP:0002168)2.27176106
76Progressive inability to walk (HP:0002505)2.27048925
77Disproportionate short-trunk short stature (HP:0003521)2.26976978
78IgG deficiency (HP:0004315)2.25662767
79Attenuation of retinal blood vessels (HP:0007843)2.25538903
80Aplasia/Hypoplasia of the fovea (HP:0008060)2.24836586
81Hypoplasia of the fovea (HP:0007750)2.24836586
82Radial bowing (HP:0002986)2.24068299
83Thickened helices (HP:0000391)2.23907958
84Increased serum pyruvate (HP:0003542)2.23467421
85Abnormality of glycolysis (HP:0004366)2.23467421
86Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.22805815
87Intention tremor (HP:0002080)2.20785863
88Broad ribs (HP:0000885)2.20285635
89Premature rupture of membranes (HP:0001788)2.18765243
90Abnormality of the septum pellucidum (HP:0007375)2.17314562
91Hypoplastic nipples (HP:0002557)2.16861077
92Peripheral hypomyelination (HP:0007182)2.15878819
93Acute necrotizing encephalopathy (HP:0006965)2.12899897
94Bony spicule pigmentary retinopathy (HP:0007737)2.12865069
95Slow saccadic eye movements (HP:0000514)2.11796234
96Infantile muscular hypotonia (HP:0008947)2.11610849
97Fair hair (HP:0002286)2.10706426
98IgM deficiency (HP:0002850)2.10260638
99Hemiparesis (HP:0001269)2.10154000
100Anteriorly placed anus (HP:0001545)2.09814228
101Type II lissencephaly (HP:0007260)2.09749924
102Atonic seizures (HP:0010819)2.08704876
103Hyperventilation (HP:0002883)2.07208658
104Congenital hepatic fibrosis (HP:0002612)2.06841039
105Hypoplasia of the iris (HP:0007676)2.06753629
106Femoral bowing (HP:0002980)2.06459636
107Aplasia/Hypoplasia of the tibia (HP:0005772)2.06204214
108Coronal craniosynostosis (HP:0004440)2.02579353
109Abnormality of the fovea (HP:0000493)2.01430484
110Lipid accumulation in hepatocytes (HP:0006561)1.99167280
111Decreased electroretinogram (ERG) amplitude (HP:0000654)1.97212709
112Myelomeningocele (HP:0002475)1.96012832
113Small hand (HP:0200055)1.95181779
114Aplasia/Hypoplasia of the fibula (HP:0006492)1.94914315
115Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.94858890
116Cerebral hypomyelination (HP:0006808)1.94552260
117Gait imbalance (HP:0002141)1.94431808
118Agitation (HP:0000713)1.93967086
119Polyuria (HP:0000103)1.93473256
120Onion bulb formation (HP:0003383)1.92124593
121Symphalangism affecting the phalanges of the hand (HP:0009773)1.91887082
122Cerebral hemorrhage (HP:0001342)1.91643658
123Hypothermia (HP:0002045)1.89721397
124Progressive macrocephaly (HP:0004481)1.89395967
125Enlarged epiphyses (HP:0010580)1.89184641
126Abnormal eating behavior (HP:0100738)1.89150501
127Severe muscular hypotonia (HP:0006829)1.88472494
128Cystic liver disease (HP:0006706)1.88395617
129Aplasia/Hypoplasia of the lens (HP:0008063)1.87121743
130Genital tract atresia (HP:0001827)1.86551539
131Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.86249530
132Congenital primary aphakia (HP:0007707)1.85780122
133Sclerocornea (HP:0000647)1.85599951
134Choroideremia (HP:0001139)1.84884670
135Abnormality of the parathyroid morphology (HP:0011766)1.84667522
136Keratoconus (HP:0000563)1.84639410
137Increased corneal curvature (HP:0100692)1.84639410
138Bilateral microphthalmos (HP:0007633)1.84560940
139Generalized hypopigmentation of hair (HP:0011358)1.83403737
140Bile duct proliferation (HP:0001408)1.83157443
141Abnormal biliary tract physiology (HP:0012439)1.83157443
142Short foot (HP:0001773)1.82434176
143Neuronal loss in central nervous system (HP:0002529)1.82256263
144Anterior segment dysgenesis (HP:0007700)1.82011119
145Lissencephaly (HP:0001339)1.81958599
146Bowel incontinence (HP:0002607)1.81690288
147Abnormality of dentin (HP:0010299)1.80858231
148Bulbous nose (HP:0000414)1.80775441
149Meningocele (HP:0002435)1.80187534
150Delayed closure of the anterior fontanelle (HP:0001476)1.78571426
151Stage 5 chronic kidney disease (HP:0003774)1.78509492
152Nephrogenic diabetes insipidus (HP:0009806)1.78030731
153Metaphyseal dysplasia (HP:0100255)1.77716618
154Abnormality of macular pigmentation (HP:0008002)1.77217571
155Ankle clonus (HP:0011448)1.76696208
156Leukodystrophy (HP:0002415)1.76472586
157Congenital, generalized hypertrichosis (HP:0004540)1.75849530
158Focal motor seizures (HP:0011153)1.75502122
159Pachygyria (HP:0001302)1.75462234
160Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.75143174
161Alacrima (HP:0000522)1.74895489
162Autoamputation (HP:0001218)1.74861878
163Abnormality of the pubic bones (HP:0003172)1.72691823
164Broad-based gait (HP:0002136)1.72103888
165Anencephaly (HP:0002323)1.72054049
166Exotropia (HP:0000577)1.71544906
167Abnormal large intestine physiology (HP:0012700)1.71203498
168Down-sloping shoulders (HP:0200021)1.69752987
169Barrel-shaped chest (HP:0001552)1.69178549
170Cupped ear (HP:0000378)1.68845984
171Widely spaced teeth (HP:0000687)1.68780135
172Mitochondrial inheritance (HP:0001427)1.67475016
173Abnormal mitochondria in muscle tissue (HP:0008316)1.67293212
174Progressive cerebellar ataxia (HP:0002073)1.66897068
175Hypoplastic pelvis (HP:0008839)1.66603131
176Atelectasis (HP:0100750)1.66400897
177Optic disc pallor (HP:0000543)1.66266528
178Venous insufficiency (HP:0005293)1.65857975
179Aortic dissection (HP:0002647)1.65202032
180Generalized myoclonic seizures (HP:0002123)1.65063814
181Absent speech (HP:0001344)1.64213285
182Disproportionate tall stature (HP:0001519)1.63494483
183Diplopia (HP:0000651)1.63470320
184Abnormality of binocular vision (HP:0011514)1.63470320
185Vaginal atresia (HP:0000148)1.63272451

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.53072382
2STK394.07289831
3ADRBK23.40419139
4MAPKAPK53.22878311
5TLK13.02423199
6TNIK2.96303729
7MARK12.80305556
8NTRK12.70447115
9MAP4K22.63137525
10OXSR12.59439915
11ZAK2.44585718
12EPHB22.44028653
13WNK32.37014536
14BCR2.21317766
15PINK12.18193760
16UHMK12.14288106
17MAPK132.06762888
18FES2.04183588
19CDK191.86501447
20NLK1.86464804
21GRK11.81001434
22PKN11.79667590
23FLT31.73942096
24INSRR1.67896474
25DYRK21.61575474
26EPHB11.60496967
27CSNK1G31.57654780
28ACVR1B1.55152390
29NTRK21.52039590
30EPHA31.49665256
31CASK1.47634644
32NUAK11.36961516
33PKN21.35156874
34CSNK1A1L1.31838444
35TGFBR11.28176382
36TAOK31.27715260
37MAP3K41.27195098
38FGFR21.26280520
39MAPK151.25224246
40SIK21.24310982
41MAP3K131.22463568
42PAK61.19842823
43MARK21.19505747
44CSNK1G21.19388814
45FGR1.17313469
46KSR11.16894593
47CSNK1G11.16861775
48TYRO31.15865726
49CDK81.15131310
50MAPK111.12703459
51ROCK21.11959505
52MUSK1.11787959
53EPHA41.10814211
54WNK41.10524934
55CAMK2B1.07851841
56PNCK1.05841384
57STK38L1.05372217
58PRKCI1.04506857
59CDK51.04157657
60MET1.03684926
61NTRK31.02684393
62PRKCG1.02581603
63MAP3K121.02214752
64CLK11.00473224
65NEK20.99664092
66ITK0.98430545
67MINK10.96280647
68IRAK20.95613455
69MAP2K70.94204755
70SIK30.92797216
71LIMK10.90681414
72KIT0.88687365
73ARAF0.88201099
74STK30.87587427
75BCKDK0.86261680
76DAPK20.86000774
77GRK70.85496453
78CDK140.82194823
79KSR20.81964293
80CAMK2D0.81795647
81MAP3K90.80776952
82BMPR1B0.80551283
83TIE10.79076229
84PHKG20.77412938
85PHKG10.77412938
86CAMK2A0.77389815
87KDR0.75009880
88TGFBR20.74292400
89MST40.73752052
90PAK30.73171733
91BRSK20.71512237
92PBK0.71035247
93DYRK1A0.70451531
94CDK180.70329153
95MAP3K60.69966599
96CAMK1G0.69586736
97PRKCE0.68488689
98CDK150.67555103
99MAPK120.67125612
100WNK10.67024940
101TEC0.66162638
102CSK0.66130808
103STK110.64854239
104FYN0.64590860
105EIF2AK30.63703439
106GRK50.62608962
107CDK11A0.61436877
108PRKCH0.61378051
109IRAK10.60219414
110PRKCQ0.60126102
111CSF1R0.59352754
112MAP2K40.58800479
113WEE10.57591704
114CAMKK20.57356738
115PDGFRB0.57062247
116DMPK0.56941989
117STK160.56183500
118RAF10.55726939
119ABL20.53465685
120SGK20.52322659
121SYK0.51667291
122PRPF4B0.48993918
123PLK20.48740412
124CCNB10.48033358
125STK380.47002612
126MAPK40.46987098
127RPS6KA50.46385222
128SGK4940.46376965
129SGK2230.46376965
130PRKD10.46322844
131CAMK2G0.45469926
132ROCK10.45033216
133TRIM280.44384788
134LCK0.44372786
135PRKAA10.43673172
136MOS0.43444513
137MAP2K10.43313399
138PRKG10.43302791
139TRPM70.42504145
140PRKD20.42199379
141TXK0.40428299
142FER0.38960949
143PTK2B0.38933684
144ADRBK10.38776731
145VRK10.38279553
146MAP2K60.37798325
147LATS10.33749438
148MAPKAPK30.33488264
149DYRK30.32147194
150PRKACA0.31862832

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006033.75133045
2Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006043.56012771
3Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.33471111
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.05902956
5Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.76674161
6Nitrogen metabolism_Homo sapiens_hsa009102.73360253
7Selenocompound metabolism_Homo sapiens_hsa004502.66927710
8Steroid biosynthesis_Homo sapiens_hsa001002.34835982
9Primary immunodeficiency_Homo sapiens_hsa053402.32072318
10alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.31939219
11Axon guidance_Homo sapiens_hsa043602.29390402
12Serotonergic synapse_Homo sapiens_hsa047262.05437672
13Oxidative phosphorylation_Homo sapiens_hsa001902.02212562
14Linoleic acid metabolism_Homo sapiens_hsa005911.97588053
15Basal transcription factors_Homo sapiens_hsa030221.97544877
16Maturity onset diabetes of the young_Homo sapiens_hsa049501.85526547
17Fatty acid elongation_Homo sapiens_hsa000621.82939584
18GABAergic synapse_Homo sapiens_hsa047271.73365948
19Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.72437476
20Intestinal immune network for IgA production_Homo sapiens_hsa046721.67127236
21Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.66873459
22Ether lipid metabolism_Homo sapiens_hsa005651.65447676
23Protein export_Homo sapiens_hsa030601.64923660
24Alzheimers disease_Homo sapiens_hsa050101.63496443
25Glutamatergic synapse_Homo sapiens_hsa047241.62078301
26Nicotine addiction_Homo sapiens_hsa050331.57270795
27Morphine addiction_Homo sapiens_hsa050321.55995144
28Renal cell carcinoma_Homo sapiens_hsa052111.53627350
29Basal cell carcinoma_Homo sapiens_hsa052171.52947382
30Parkinsons disease_Homo sapiens_hsa050121.49008807
31Long-term depression_Homo sapiens_hsa047301.48481018
32Circadian entrainment_Homo sapiens_hsa047131.48296887
33Cholinergic synapse_Homo sapiens_hsa047251.46413922
34Phototransduction_Homo sapiens_hsa047441.39462721
35Butanoate metabolism_Homo sapiens_hsa006501.34296120
36Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.33149023
37Dopaminergic synapse_Homo sapiens_hsa047281.25813162
38Homologous recombination_Homo sapiens_hsa034401.24534821
39Cardiac muscle contraction_Homo sapiens_hsa042601.24435846
40Fanconi anemia pathway_Homo sapiens_hsa034601.22620040
41SNARE interactions in vesicular transport_Homo sapiens_hsa041301.20605118
42Sphingolipid metabolism_Homo sapiens_hsa006001.20455573
43Sphingolipid signaling pathway_Homo sapiens_hsa040711.18963067
44Glycosaminoglycan degradation_Homo sapiens_hsa005311.18771493
45Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.15639636
46Renin secretion_Homo sapiens_hsa049241.15053435
47Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.10472375
48ECM-receptor interaction_Homo sapiens_hsa045121.10076722
49Olfactory transduction_Homo sapiens_hsa047401.08762717
50Regulation of autophagy_Homo sapiens_hsa041401.07832761
51Vibrio cholerae infection_Homo sapiens_hsa051101.07496988
52Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.07496650
53Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.07310893
54Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.03994106
55Cocaine addiction_Homo sapiens_hsa050301.03884320
56ErbB signaling pathway_Homo sapiens_hsa040121.02776791
57Salivary secretion_Homo sapiens_hsa049701.00296485
58Phospholipase D signaling pathway_Homo sapiens_hsa040720.99967580
59RNA degradation_Homo sapiens_hsa030180.99873814
60Oxytocin signaling pathway_Homo sapiens_hsa049210.99512978
61ABC transporters_Homo sapiens_hsa020100.99445693
62Ras signaling pathway_Homo sapiens_hsa040140.97757558
63Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.97015930
64Gap junction_Homo sapiens_hsa045400.96681183
65Taste transduction_Homo sapiens_hsa047420.94764881
66Synaptic vesicle cycle_Homo sapiens_hsa047210.93450040
67Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.92773233
68Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.88460172
69Vascular smooth muscle contraction_Homo sapiens_hsa042700.87777355
70Phagosome_Homo sapiens_hsa041450.86791389
71GnRH signaling pathway_Homo sapiens_hsa049120.86668063
72Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.84294936
73Long-term potentiation_Homo sapiens_hsa047200.83998460
74Collecting duct acid secretion_Homo sapiens_hsa049660.83097681
75Rheumatoid arthritis_Homo sapiens_hsa053230.82061627
76Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.81958515
77Alcoholism_Homo sapiens_hsa050340.81767294
78Gastric acid secretion_Homo sapiens_hsa049710.81264350
79Caffeine metabolism_Homo sapiens_hsa002320.80959833
80Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.80862933
81TGF-beta signaling pathway_Homo sapiens_hsa043500.80533175
82Ribosome_Homo sapiens_hsa030100.78807071
83Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.78731781
84Estrogen signaling pathway_Homo sapiens_hsa049150.78200945
85Huntingtons disease_Homo sapiens_hsa050160.77450628
86Endocytosis_Homo sapiens_hsa041440.76976147
87Tryptophan metabolism_Homo sapiens_hsa003800.76899000
88Circadian rhythm_Homo sapiens_hsa047100.76315593
89Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.75896245
90Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.75079134
91Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.74358935
92Melanogenesis_Homo sapiens_hsa049160.74130179
93Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.72639013
94Glycerolipid metabolism_Homo sapiens_hsa005610.72414092
95Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.72176461
96Dilated cardiomyopathy_Homo sapiens_hsa054140.72146643
97cAMP signaling pathway_Homo sapiens_hsa040240.72011474
98Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.71587023
99Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.70469663
100Chemokine signaling pathway_Homo sapiens_hsa040620.70201031
101Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.69618910
102Aldosterone synthesis and secretion_Homo sapiens_hsa049250.69020180
103Focal adhesion_Homo sapiens_hsa045100.68975999
104B cell receptor signaling pathway_Homo sapiens_hsa046620.68371955
105Choline metabolism in cancer_Homo sapiens_hsa052310.68359246
106Colorectal cancer_Homo sapiens_hsa052100.67710271
107Glioma_Homo sapiens_hsa052140.66996382
108Hippo signaling pathway_Homo sapiens_hsa043900.66868836
109Amphetamine addiction_Homo sapiens_hsa050310.66651099
110Ovarian steroidogenesis_Homo sapiens_hsa049130.66475745
111Platelet activation_Homo sapiens_hsa046110.64563698
112VEGF signaling pathway_Homo sapiens_hsa043700.62801616
113Wnt signaling pathway_Homo sapiens_hsa043100.62255034
114N-Glycan biosynthesis_Homo sapiens_hsa005100.60700695
115Insulin secretion_Homo sapiens_hsa049110.60353032
116Leukocyte transendothelial migration_Homo sapiens_hsa046700.60325543
117Malaria_Homo sapiens_hsa051440.59908626
118T cell receptor signaling pathway_Homo sapiens_hsa046600.59194322
119RNA polymerase_Homo sapiens_hsa030200.59094059
120Hedgehog signaling pathway_Homo sapiens_hsa043400.58949411
121Rap1 signaling pathway_Homo sapiens_hsa040150.57991428
122MAPK signaling pathway_Homo sapiens_hsa040100.57905962
123cGMP-PKG signaling pathway_Homo sapiens_hsa040220.56246173
124Pancreatic cancer_Homo sapiens_hsa052120.53483046
125Calcium signaling pathway_Homo sapiens_hsa040200.53354795
126PI3K-Akt signaling pathway_Homo sapiens_hsa041510.52308227
127Regulation of actin cytoskeleton_Homo sapiens_hsa048100.51685006
128Glycerophospholipid metabolism_Homo sapiens_hsa005640.51195961
129Sulfur relay system_Homo sapiens_hsa041220.51178507
130Dorso-ventral axis formation_Homo sapiens_hsa043200.50543634
131Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.49161224
132Tight junction_Homo sapiens_hsa045300.48946256
133Shigellosis_Homo sapiens_hsa051310.48649830
134Primary bile acid biosynthesis_Homo sapiens_hsa001200.48237211
135Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.47886476
136Arachidonic acid metabolism_Homo sapiens_hsa005900.37220481
137Type II diabetes mellitus_Homo sapiens_hsa049300.36060359
138Melanoma_Homo sapiens_hsa052180.34373016
139p53 signaling pathway_Homo sapiens_hsa041150.33134940
140Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.32959599
141Metabolic pathways_Homo sapiens_hsa011000.32769206
142Steroid hormone biosynthesis_Homo sapiens_hsa001400.31880678
143Fructose and mannose metabolism_Homo sapiens_hsa000510.30307330
144Pathways in cancer_Homo sapiens_hsa052000.27236343
145Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.25914320

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