FUT7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X antigens. The encoded protein can direct the synthesis of the E-selectin-binding sialyl-Lewis X moiety. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.75720660
2negative regulation of cell killing (GO:0031342)6.18314405
3negative regulation of leukocyte mediated cytotoxicity (GO:0001911)6.18314405
4DNA deamination (GO:0045006)5.78520348
5positive regulation by symbiont of host defense response (GO:0052509)5.67714577
6modulation by symbiont of host defense response (GO:0052031)5.67714577
7modulation by organism of immune response of other organism involved in symbiotic interaction (GO:005.67714577
8modulation by organism of defense response of other organism involved in symbiotic interaction (GO:05.67714577
9positive regulation by organism of defense response of other organism involved in symbiotic interact5.67714577
10modulation by symbiont of host immune response (GO:0052553)5.67714577
11viral transcription (GO:0019083)5.30700132
12antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.29185890
13leukocyte aggregation (GO:0070486)5.27950896
14detection of other organism (GO:0098543)5.23118173
15detection of bacterium (GO:0016045)5.13175478
16antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.12032402
17antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.12032402
18translational termination (GO:0006415)5.07489137
19response to peptidoglycan (GO:0032494)4.81931931
20antigen processing and presentation via MHC class Ib (GO:0002475)4.78822158
21positive regulation of B cell differentiation (GO:0045579)4.72203336
22macrophage activation involved in immune response (GO:0002281)4.69539469
23leukocyte migration involved in inflammatory response (GO:0002523)4.67223108
24mast cell activation (GO:0045576)4.62708319
25SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.59758872
26cotranslational protein targeting to membrane (GO:0006613)4.50563609
27protein targeting to ER (GO:0045047)4.46085778
28DNA strand elongation involved in DNA replication (GO:0006271)4.45330314
29translational elongation (GO:0006414)4.44007221
30ribosomal small subunit biogenesis (GO:0042274)4.37524069
31response to interleukin-15 (GO:0070672)4.33565554
32detection of external biotic stimulus (GO:0098581)4.33170192
33negative regulation of lymphocyte mediated immunity (GO:0002707)4.32350063
34telomere maintenance via semi-conservative replication (GO:0032201)4.31182422
35DNA strand elongation (GO:0022616)4.29067835
36antigen processing and presentation of endogenous antigen (GO:0019883)4.25413623
37protein localization to endoplasmic reticulum (GO:0070972)4.24427046
38establishment of protein localization to endoplasmic reticulum (GO:0072599)4.23960486
39neutrophil activation (GO:0042119)4.23539901
40negative regulation of interleukin-12 production (GO:0032695)4.18038854
41mast cell activation involved in immune response (GO:0002279)4.17485715
42mast cell degranulation (GO:0043303)4.17485715
43regulation of gamma-delta T cell activation (GO:0046643)4.09996056
44regulation of interferon-beta biosynthetic process (GO:0045357)4.06977898
45response to host immune response (GO:0052572)4.06690233
46response to immune response of other organism involved in symbiotic interaction (GO:0052564)4.06690233
47cellular response to interleukin-15 (GO:0071350)4.00283181
48immunoglobulin mediated immune response (GO:0016064)3.98048179
49negative regulation of leukocyte mediated immunity (GO:0002704)3.90805443
50nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.90761835
51maturation of SSU-rRNA (GO:0030490)3.89625082
52negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.88516625
53regulation of mast cell degranulation (GO:0043304)3.85940499
54detection of molecule of bacterial origin (GO:0032490)3.84133718
55viral life cycle (GO:0019058)3.83136760
56cellular protein complex disassembly (GO:0043624)3.82748155
57detection of biotic stimulus (GO:0009595)3.79229843
58granulocyte activation (GO:0036230)3.78961068
59negative regulation of T cell mediated immunity (GO:0002710)3.76957493
60negative regulation of phagocytosis (GO:0050765)3.75630299
61regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.73101064
62response to host defenses (GO:0052200)3.72809345
63response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.72809345
64response to host (GO:0075136)3.72809345
65regulation of gamma-delta T cell differentiation (GO:0045586)3.71617235
66positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.70130354
67telomere maintenance via recombination (GO:0000722)3.69000582
68platelet dense granule organization (GO:0060155)3.68742571
69microglial cell activation (GO:0001774)3.67729438
70regulation of myeloid leukocyte mediated immunity (GO:0002886)3.67683855
71IMP metabolic process (GO:0046040)3.63627048
72type I interferon signaling pathway (GO:0060337)3.61657650
73cellular response to type I interferon (GO:0071357)3.61657650
74response to type I interferon (GO:0034340)3.58792413
75regulation of mast cell activation involved in immune response (GO:0033006)3.57216923
76translational initiation (GO:0006413)3.55166470
77regulation of B cell differentiation (GO:0045577)3.55165562
78definitive hemopoiesis (GO:0060216)3.54849240
79DNA unwinding involved in DNA replication (GO:0006268)3.54258427
80response to interferon-beta (GO:0035456)3.53414821
81respiratory burst (GO:0045730)3.50115961
82positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.48647789
83regulation of leukocyte degranulation (GO:0043300)3.48419557
84macrophage activation (GO:0042116)3.46104120
85negative thymic T cell selection (GO:0045060)3.45199401
86DNA replication initiation (GO:0006270)3.44256419
87Arp2/3 complex-mediated actin nucleation (GO:0034314)3.42086292
88protein complex disassembly (GO:0043241)3.39654254
89positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.35787975
90regulation of mast cell activation (GO:0033003)3.33625783
91lymphoid progenitor cell differentiation (GO:0002320)3.33400912
92B cell mediated immunity (GO:0019724)3.31993628
93positive regulation of mast cell activation (GO:0033005)3.31977351
94negative T cell selection (GO:0043383)3.30589476
95response to muramyl dipeptide (GO:0032495)3.30022419
96mitotic recombination (GO:0006312)3.29787086
97negative regulation of type 2 immune response (GO:0002829)3.29279902
98necroptotic process (GO:0070266)3.29103402
99production of molecular mediator involved in inflammatory response (GO:0002532)3.24281285
100negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.22457678
101negative regulation of T-helper cell differentiation (GO:0045623)3.22457678
102positive thymic T cell selection (GO:0045059)3.22019975
103regulation of dendritic cell antigen processing and presentation (GO:0002604)3.20371091
104positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.17392936
105germinal center formation (GO:0002467)3.17308066
106neutrophil mediated immunity (GO:0002446)3.14563513
107macromolecular complex disassembly (GO:0032984)3.14370923
108cellular extravasation (GO:0045123)3.12250466
109interferon-gamma-mediated signaling pathway (GO:0060333)3.11627007
110positive regulation of gamma-delta T cell activation (GO:0046645)3.10365077
111telomere maintenance via telomere lengthening (GO:0010833)3.08567906
112regulation of T-helper 2 cell differentiation (GO:0045628)3.07296337
113regulation of T cell tolerance induction (GO:0002664)3.05060587
114activated T cell proliferation (GO:0050798)3.04122000
115nuclear-transcribed mRNA catabolic process (GO:0000956)3.04121039
116regulation of regulated secretory pathway (GO:1903305)3.04094385
117negative regulation of innate immune response (GO:0045824)3.03477149
118negative regulation of interleukin-6 production (GO:0032715)3.03033800
119negative regulation of cytokine production involved in immune response (GO:0002719)3.02175468
120response to protozoan (GO:0001562)3.01180377
121regulation of tolerance induction (GO:0002643)3.01005607
122cellular response to zinc ion (GO:0071294)3.00296289
123regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.99051387
124negative regulation of growth of symbiont in host (GO:0044130)2.99021300
125negative regulation of growth of symbiont involved in interaction with host (GO:0044146)2.99021300
126modulation of growth of symbiont involved in interaction with host (GO:0044144)2.99021300
127regulation of growth of symbiont in host (GO:0044126)2.99021300
128defense response to protozoan (GO:0042832)2.98197051
129endosome to pigment granule transport (GO:0043485)2.96836765
130endosome to melanosome transport (GO:0035646)2.96836765
131deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.96795839
132positive regulation of interferon-alpha production (GO:0032727)2.96488086
133nucleotide-excision repair, DNA gap filling (GO:0006297)2.96280250
134dendritic cell chemotaxis (GO:0002407)2.95061247
135protein targeting to membrane (GO:0006612)2.95026268
136hepatocyte apoptotic process (GO:0097284)2.94004303
137neutrophil chemotaxis (GO:0030593)2.92014303
138T cell homeostasis (GO:0043029)2.91735181
139IMP biosynthetic process (GO:0006188)2.91479459
140negative regulation of erythrocyte differentiation (GO:0045647)2.91356851
141positive regulation of antigen processing and presentation (GO:0002579)2.91195199
142leukocyte degranulation (GO:0043299)2.90974503
143mRNA catabolic process (GO:0006402)2.90755279
144dendritic cell migration (GO:0036336)2.89353367
145positive regulation of mast cell activation involved in immune response (GO:0033008)2.89048638
146cellular response to interferon-beta (GO:0035458)2.88666014
147megakaryocyte development (GO:0035855)2.85658239
148secretory granule organization (GO:0033363)2.84213631
149regulation of B cell receptor signaling pathway (GO:0050855)2.78678998
150RNA catabolic process (GO:0006401)2.77509975
151pentose-phosphate shunt (GO:0006098)2.76941186
152positive regulation of granulocyte differentiation (GO:0030854)2.76531396
153regulation of erythrocyte differentiation (GO:0045646)2.73062393
154macrophage differentiation (GO:0030225)2.73058037
155angiogenesis involved in wound healing (GO:0060055)2.71567821
156ribosomal large subunit biogenesis (GO:0042273)2.70146001
157B cell receptor signaling pathway (GO:0050853)2.69543359
158neutrophil activation involved in immune response (GO:0002283)2.68603676
159pseudouridine synthesis (GO:0001522)2.68447801
160programmed necrotic cell death (GO:0097300)2.67493120
161response to interferon-alpha (GO:0035455)2.65553981
162T cell migration (GO:0072678)2.65151200
163translation (GO:0006412)2.63230139
164myeloid leukocyte mediated immunity (GO:0002444)2.60973770
165mature B cell differentiation involved in immune response (GO:0002313)2.59507929
166regulation of necroptotic process (GO:0060544)2.58234827
167killing of cells in other organism involved in symbiotic interaction (GO:0051883)2.56490595
168disruption of cells of other organism involved in symbiotic interaction (GO:0051818)2.56490595
169ribonucleoprotein complex biogenesis (GO:0022613)2.55922633
170nucleobase biosynthetic process (GO:0046112)2.54624678
171myeloid cell activation involved in immune response (GO:0002275)2.52369363
172defense response to fungus (GO:0050832)2.51978380
1733-UTR-mediated mRNA stabilization (GO:0070935)2.49597544
174purine-containing compound salvage (GO:0043101)2.49267479

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.39939295
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.49083690
3SCL_19346495_ChIP-Seq_HPC-7_Human3.23636026
4* MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.02313594
5SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.99890020
6MYC_18555785_ChIP-Seq_MESCs_Mouse2.91914080
7ELF1_17652178_ChIP-ChIP_JURKAT_Human2.91376544
8BP1_19119308_ChIP-ChIP_Hs578T_Human2.82953911
9SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.82260567
10IRF8_22096565_ChIP-ChIP_GC-B_Human2.77723063
11MYB_21317192_ChIP-Seq_ERMYB_Mouse2.76263615
12IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.75081340
13* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.68489027
14FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.50525511
15* TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.47613780
16RUNX_20019798_ChIP-Seq_JUKART_Human2.42468066
17* VDR_21846776_ChIP-Seq_THP-1_Human2.41577634
18SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.41321189
19EGR1_19374776_ChIP-ChIP_THP-1_Human2.32207940
20E2F4_17652178_ChIP-ChIP_JURKAT_Human2.25345755
21* SPI1_23547873_ChIP-Seq_NB4_Human2.21793579
22MYC_22102868_ChIP-Seq_BL_Human2.16783943
23IRF8_21731497_ChIP-ChIP_J774_Mouse2.14627280
24NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.14303409
25VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.07219163
26MYC_18358816_ChIP-ChIP_MESCs_Mouse2.06243250
27STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.04167879
28SFPI1_20887958_ChIP-Seq_HPC-7_Mouse2.03362656
29EST1_17652178_ChIP-ChIP_JURKAT_Human2.02640721
30HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.01322770
31ERG_20887958_ChIP-Seq_HPC-7_Mouse1.99260955
32GABP_17652178_ChIP-ChIP_JURKAT_Human1.99153603
33HOXB4_20404135_ChIP-ChIP_EML_Mouse1.96733543
34* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.95543199
35GATA1_22025678_ChIP-Seq_K562_Human1.88460488
36STAT4_19710469_ChIP-ChIP_TH1__Mouse1.88015726
37ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.87906211
38JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.86202619
39VDR_23849224_ChIP-Seq_CD4+_Human1.85910703
40KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.84575479
41NOTCH1_21737748_ChIP-Seq_TLL_Human1.84552010
42KDM2B_26808549_Chip-Seq_DND41_Human1.83907172
43* VDR_24763502_ChIP-Seq_THP-1_Human1.82170919
44* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.80785655
45ETS1_20019798_ChIP-Seq_JURKAT_Human1.77797381
46MYC_19030024_ChIP-ChIP_MESCs_Mouse1.77482604
47MYC_19079543_ChIP-ChIP_MESCs_Mouse1.76996938
48FOXP3_21729870_ChIP-Seq_TREG_Human1.75636363
49RUNX1_22412390_ChIP-Seq_EML_Mouse1.74762738
50CIITA_25753668_ChIP-Seq_RAJI_Human1.74307790
51LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.74234319
52* MYB_26560356_Chip-Seq_TH2_Human1.72115571
53NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.71346807
54FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.69900324
55GATA3_27048872_Chip-Seq_THYMUS_Human1.68132088
56IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.64279944
57* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.64130143
58* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.62380688
59* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.61017716
60KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.60342310
61XRN2_22483619_ChIP-Seq_HELA_Human1.60066204
62SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.57806643
63NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.56455315
64CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.56334630
65GATA1_22383799_ChIP-Seq_G1ME_Mouse1.55883838
66FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.55655173
67* MAF_26560356_Chip-Seq_TH1_Human1.55514381
68* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.52892170
69LXR_22292898_ChIP-Seq_THP-1_Human1.52886160
70VDR_24787735_ChIP-Seq_THP-1_Human1.51623884
71CREB1_15753290_ChIP-ChIP_HEK293T_Human1.50818062
72* MYB_26560356_Chip-Seq_TH1_Human1.50661049
73THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.49593031
74CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.44838804
75ELK3_25401928_ChIP-Seq_HUVEC_Human1.43841966
76PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.43213916
77UTX_26944678_Chip-Seq_JUKART_Human1.42545442
78CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.40888893
79RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.40463755
80FOXM1_23109430_ChIP-Seq_U2OS_Human1.38988189
81GATA2_22383799_ChIP-Seq_G1ME_Mouse1.37735896
82IRF8_27001747_Chip-Seq_BMDM_Mouse1.36526343
83SRF_21415370_ChIP-Seq_HL-1_Mouse1.36449680
84BCL6_27268052_Chip-Seq_Bcells_Human1.36323261
85PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.35624920
86DCP1A_22483619_ChIP-Seq_HELA_Human1.35010901
87E2F1_21310950_ChIP-Seq_MCF-7_Human1.30824693
88HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.30264188
89Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.29972522
90FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.29561386
91SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.28663612
92MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.28328965
93CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.27020795
94BCOR_27268052_Chip-Seq_Bcells_Human1.26931441
95E2F1_18555785_ChIP-Seq_MESCs_Mouse1.24816511
96GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.24563236
97* TCF7_22412390_ChIP-Seq_EML_Mouse1.23619246
98NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.22696758
99GATA3_26560356_Chip-Seq_TH2_Human1.22429832
100NELFA_20434984_ChIP-Seq_ESCs_Mouse1.20977016
101* STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.19278121
102TTF2_22483619_ChIP-Seq_HELA_Human1.18934853
103GABP_19822575_ChIP-Seq_HepG2_Human1.18752707
104GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.18709572
105IKZF1_21737484_ChIP-ChIP_HCT116_Human1.18356064
106CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.17819124
107STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.16467696
108FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.16110837
109ELK1_19687146_ChIP-ChIP_HELA_Human1.15137512
110KDM2B_26808549_Chip-Seq_JURKAT_Human1.14122974
111ELF1_20517297_ChIP-Seq_JURKAT_Human1.13890024
112E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.13677918
113VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.13051771
114CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.12575526
115PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.11975477
116YY1_21170310_ChIP-Seq_MESCs_Mouse1.11544954
117SPI1_23127762_ChIP-Seq_K562_Human1.11517602
118ZFX_18555785_ChIP-Seq_MESCs_Mouse1.11254012
119RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.06989401
120THAP11_20581084_ChIP-Seq_MESCs_Mouse1.06871810
121CTCF_27219007_Chip-Seq_ERYTHROID_Human1.05293652
122GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.05206661
123SPI1_20517297_ChIP-Seq_HL60_Human1.04608208
124GATA1_19941826_ChIP-Seq_K562_Human1.04126902
125TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.03863209
126P68_20966046_ChIP-Seq_HELA_Human1.01485196
127* MAF_26560356_Chip-Seq_TH2_Human1.01328879
128CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.00964549
129SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.00692050
130TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.99158822
131PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.99044953
132RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.97129974
133PU_27001747_Chip-Seq_BMDM_Mouse0.96283743
134MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.95020871
135NCOR1_26117541_ChIP-Seq_K562_Human0.94198134
136* SA1_27219007_Chip-Seq_ERYTHROID_Human0.93945329
137GATA1_19941827_ChIP-Seq_MEL_Mouse0.92539980
138FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92253043
139MYCN_18555785_ChIP-Seq_MESCs_Mouse0.92097969
140PU.1_20513432_ChIP-Seq_Bcells_Mouse0.90660797
141E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.90305445
142PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.86004976
143SMAD_19615063_ChIP-ChIP_OVARY_Human0.84648937
144STAT6_21828071_ChIP-Seq_BEAS2B_Human0.84610832
145SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.84044184

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002396_abnormal_hematopoietic_system4.57704443
2MP0001835_abnormal_antigen_presentation3.58892870
3MP0005075_abnormal_melanosome_morpholog3.19438627
4MP0009785_altered_susceptibility_to2.97167369
5MP0002166_altered_tumor_susceptibility2.93319394
6MP0003436_decreased_susceptibility_to2.92746582
7MP0001545_abnormal_hematopoietic_system2.75318325
8MP0005397_hematopoietic_system_phenotyp2.75318325
9MP0005464_abnormal_platelet_physiology2.73945122
10MP0005671_abnormal_response_to2.66756134
11MP0000685_abnormal_immune_system2.66232276
12MP0005174_abnormal_tail_pigmentation2.64308862
13MP0005025_abnormal_response_to2.51850158
14MP0002006_tumorigenesis2.45707353
15MP0003763_abnormal_thymus_physiology2.43155761
16MP0000465_gastrointestinal_hemorrhage2.41000374
17MP0004808_abnormal_hematopoietic_stem2.39855537
18MP0005000_abnormal_immune_tolerance2.35682016
19* MP0002419_abnormal_innate_immunity2.30200924
20MP0003724_increased_susceptibility_to2.29870787
21* MP0002398_abnormal_bone_marrow2.27971004
22MP0003693_abnormal_embryo_hatching2.26788033
23* MP0002420_abnormal_adaptive_immunity2.22973500
24* MP0001819_abnormal_immune_cell2.17311970
25MP0001800_abnormal_humoral_immune2.17137362
26MP0000490_abnormal_crypts_of2.15698379
27MP0002723_abnormal_immune_serum2.11767463
28MP0002452_abnormal_antigen_presenting2.11044397
29MP0001853_heart_inflammation2.09272366
30* MP0002148_abnormal_hypersensitivity_rea2.08926618
31MP0009333_abnormal_splenocyte_physiolog2.04884736
32MP0000689_abnormal_spleen_morphology1.98915766
33MP0000716_abnormal_immune_system1.97108777
34MP0010094_abnormal_chromosome_stability1.96290736
35MP0008057_abnormal_DNA_replication1.95080191
36* MP0002722_abnormal_immune_system1.93214732
37MP0010155_abnormal_intestine_physiology1.84850207
38MP0002429_abnormal_blood_cell1.83172207
39MP0003866_abnormal_defecation1.81249168
40MP0003172_abnormal_lysosome_physiology1.70847043
41MP0003300_gastrointestinal_ulcer1.69457085
42MP0008260_abnormal_autophagy1.65309521
43MP0001873_stomach_inflammation1.62892950
44MP0009379_abnormal_foot_pigmentation1.62807267
45MP0003828_pulmonary_edema1.58810595
46MP0002405_respiratory_system_inflammati1.52964396
47MP0000703_abnormal_thymus_morphology1.52756259
48MP0001845_abnormal_inflammatory_respons1.52521297
49MP0002095_abnormal_skin_pigmentation1.51394676
50MP0003111_abnormal_nucleus_morphology1.49620705
51MP0003303_peritoneal_inflammation1.49056228
52MP0006054_spinal_hemorrhage1.46831682
53* MP0005387_immune_system_phenotype1.46585151
54* MP0001790_abnormal_immune_system1.46585151
55MP0003656_abnormal_erythrocyte_physiolo1.45670497
56MP0002277_abnormal_respiratory_mucosa1.43150313
57MP0005451_abnormal_body_composition1.42769095
58MP0004957_abnormal_blastocyst_morpholog1.42519446
59MP0003077_abnormal_cell_cycle1.38640046
60MP0008007_abnormal_cellular_replicative1.34546311
61MP0002009_preneoplasia1.33257231
62MP0009278_abnormal_bone_marrow1.32797942
63MP0002019_abnormal_tumor_incidence1.32685043
64MP0008469_abnormal_protein_level1.30485276
65MP0004381_abnormal_hair_follicle1.27964332
66MP0001986_abnormal_taste_sensitivity1.26392787
67MP0004147_increased_porphyrin_level1.21309493
68MP0001533_abnormal_skeleton_physiology1.20887730
69MP0000015_abnormal_ear_pigmentation1.20699989
70MP0008058_abnormal_DNA_repair1.18814677
71MP0004883_abnormal_blood_vessel1.16179073
72MP0000371_diluted_coat_color1.13333722
73* MP0000858_altered_metastatic_potential1.12482288
74MP0002998_abnormal_bone_remodeling1.12273836
75MP0000343_altered_response_to1.07965878
76MP0003191_abnormal_cellular_cholesterol1.02601320
77MP0004510_myositis0.94215372
78MP0005166_decreased_susceptibility_to0.93200969
79MP0004947_skin_inflammation0.92917575
80MP0003690_abnormal_glial_cell0.92907422
81MP0003806_abnormal_nucleotide_metabolis0.92727913
82MP0002933_joint_inflammation0.92359290
83MP0005058_abnormal_lysosome_morphology0.90447987
84MP0005164_abnormal_response_to0.90173806
85MP0000313_abnormal_cell_death0.89750034
86MP0005390_skeleton_phenotype0.88214868
87MP0002075_abnormal_coat/hair_pigmentati0.87124711
88MP0010352_gastrointestinal_tract_polyps0.84752308
89MP0003183_abnormal_peptide_metabolism0.84509240
90MP0006036_abnormal_mitochondrial_physio0.83873258
91MP0009763_increased_sensitivity_to0.81781284
92MP0009764_decreased_sensitivity_to0.76896003
93MP0003075_altered_response_to0.74917167
94MP0008873_increased_physiological_sensi0.74032376
95MP0001663_abnormal_digestive_system0.73893347
96MP0000604_amyloidosis0.73662902
97MP0000372_irregular_coat_pigmentation0.73216990
98MP0003186_abnormal_redox_activity0.70566393
99MP0003786_premature_aging0.69168683
100MP0002132_abnormal_respiratory_system0.67967099
101MP0001851_eye_inflammation0.66500250
102MP0008874_decreased_physiological_sensi0.65612755
103MP0005319_abnormal_enzyme/_coenzyme0.64901103
104MP0009765_abnormal_xenobiotic_induced0.64743337
105MP0000350_abnormal_cell_proliferation0.63679263
106MP0003795_abnormal_bone_structure0.63335581
107MP0008004_abnormal_stomach_pH0.62661508
108MP0005584_abnormal_enzyme/coenzyme_acti0.61745805
109MP0010307_abnormal_tumor_latency0.60952907
110MP0003448_altered_tumor_morphology0.59810741
111MP0006082_CNS_inflammation0.59424604
112MP0001186_pigmentation_phenotype0.58186333
113MP0009840_abnormal_foam_cell0.58143420
114MP0005409_darkened_coat_color0.57587256
115* MP0000477_abnormal_intestine_morphology0.56399319
116MP0005310_abnormal_salivary_gland0.56301766
117MP0000249_abnormal_blood_vessel0.53828545
118MP0001764_abnormal_homeostasis0.52734768
119MP0000598_abnormal_liver_morphology0.51761933
120MP0003045_fibrosis0.49665468
121MP0005083_abnormal_biliary_tract0.48888886
122MP0002693_abnormal_pancreas_physiology0.48063400
123MP0002928_abnormal_bile_duct0.47818997
124MP0004130_abnormal_muscle_cell0.47345995
125MP0002653_abnormal_ependyma_morphology0.46962993
126MP0003221_abnormal_cardiomyocyte_apopto0.46811250
127MP0002133_abnormal_respiratory_system0.45682390
128MP0005388_respiratory_system_phenotype0.45682390
129MP0005377_hearing/vestibular/ear_phenot0.45485845
130MP0003878_abnormal_ear_physiology0.45485845

Predicted human phenotypes

RankGene SetZ-score
1Aplastic anemia (HP:0001915)6.02202616
2Thrombocytosis (HP:0001894)5.79719020
3Elevated erythrocyte sedimentation rate (HP:0003565)5.19828084
4Stomatitis (HP:0010280)5.07614465
5Recurrent gram-negative bacterial infections (HP:0005420)5.01041328
6IgM deficiency (HP:0002850)4.73245554
7Chronic otitis media (HP:0000389)4.72573386
8Abnormality of cells of the erythroid lineage (HP:0012130)4.65239177
9Abnormal number of erythroid precursors (HP:0012131)4.63110966
10Myositis (HP:0100614)4.52774044
11Recurrent abscess formation (HP:0002722)3.99198986
12Petechiae (HP:0000967)3.95748712
13Gastrointestinal infarctions (HP:0005244)3.89924785
14Hypochromic microcytic anemia (HP:0004840)3.88074984
15Reticulocytopenia (HP:0001896)3.84985789
16Recurrent bacterial skin infections (HP:0005406)3.63439410
17Urticaria (HP:0001025)3.60375004
18Gingivitis (HP:0000230)3.55440089
19Reduced antithrombin III activity (HP:0001976)3.55072019
20Hypochromic anemia (HP:0001931)3.43306366
21Abnormality of T cell physiology (HP:0011840)3.40625596
22Prolonged bleeding time (HP:0003010)3.36821007
23Keratoconjunctivitis (HP:0001096)3.24745382
24Agammaglobulinemia (HP:0004432)3.11380972
25Episodic fever (HP:0001954)3.02076348
26Epistaxis (HP:0000421)3.01530513
27Type I transferrin isoform profile (HP:0003642)2.90576361
28Recurrent viral infections (HP:0004429)2.89854685
29Hemoptysis (HP:0002105)2.87735335
30Abnormal delayed hypersensitivity skin test (HP:0002963)2.87391893
31Nasal polyposis (HP:0100582)2.86074329
32Recurrent bronchitis (HP:0002837)2.85442264
33Pallor (HP:0000980)2.85359314
34Abnormality of macrophages (HP:0004311)2.84649476
35Osteomyelitis (HP:0002754)2.84154318
36Sepsis (HP:0100806)2.80886082
37Pustule (HP:0200039)2.77546524
38Panhypogammaglobulinemia (HP:0003139)2.73913417
39Meningitis (HP:0001287)2.73132330
40T lymphocytopenia (HP:0005403)2.69644070
41Increased IgM level (HP:0003496)2.66443895
42Abnormality of B cell number (HP:0010975)2.65921125
43B lymphocytopenia (HP:0010976)2.65921125
44Recurrent fungal infections (HP:0002841)2.61852237
45Abnormality of T cells (HP:0002843)2.60805650
46Eczematoid dermatitis (HP:0000976)2.60335639
47Abnormality of T cell number (HP:0011839)2.59897552
48Anorexia (HP:0002039)2.58749017
49Abnormal platelet function (HP:0011869)2.58465814
50Impaired platelet aggregation (HP:0003540)2.58465814
51Abnormal protein glycosylation (HP:0012346)2.57088472
52Abnormal glycosylation (HP:0012345)2.57088472
53Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.57088472
54Abnormal protein N-linked glycosylation (HP:0012347)2.57088472
55Abnormality of the nasal mucosa (HP:0000433)2.54964882
56Spontaneous hematomas (HP:0007420)2.52608778
57Chronic obstructive pulmonary disease (HP:0006510)2.51671262
58Obstructive lung disease (HP:0006536)2.51671262
5911 pairs of ribs (HP:0000878)2.51362471
60Orchitis (HP:0100796)2.51053752
61Recurrent skin infections (HP:0001581)2.50791833
62Arterial thrombosis (HP:0004420)2.50231999
63Gastrointestinal inflammation (HP:0004386)2.49843180
64Lymphoma (HP:0002665)2.49646101
65Macrocytic anemia (HP:0001972)2.49571195
66Interstitial pulmonary disease (HP:0006530)2.49407000
67Pancytopenia (HP:0001876)2.48268938
68Pulmonary embolism (HP:0002204)2.47710007
69Chest pain (HP:0100749)2.47699788
70Peritonitis (HP:0002586)2.46866726
71Mediastinal lymphadenopathy (HP:0100721)2.46450287
72Axonal loss (HP:0003447)2.45717638
73Amyloidosis (HP:0011034)2.44662894
74Albinism (HP:0001022)2.44303511
75Colitis (HP:0002583)2.43210950
76Gingival bleeding (HP:0000225)2.41224041
77Abnormality of the prostate (HP:0008775)2.41105999
78Myelodysplasia (HP:0002863)2.40508051
79Eosinophilia (HP:0001880)2.39136094
80Inflammation of the large intestine (HP:0002037)2.38438270
81Hepatosplenomegaly (HP:0001433)2.37256592
82Papilledema (HP:0001085)2.33558957
83Agnosia (HP:0010524)2.33364947
84Abnormality of the pleura (HP:0002103)2.33034157
85Broad face (HP:0000283)2.32926223
86Vacuolated lymphocytes (HP:0001922)2.30038853
87Cellulitis (HP:0100658)2.29996308
88Encephalitis (HP:0002383)2.28815128
89Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.28765129
90Skin ulcer (HP:0200042)2.27291244
91Lymphopenia (HP:0001888)2.27120566
92Amyotrophic lateral sclerosis (HP:0007354)2.24818018
93Autoimmune thrombocytopenia (HP:0001973)2.22963100
94Recurrent pneumonia (HP:0006532)2.22311332
95Acute myeloid leukemia (HP:0004808)2.21419058
96Abnormality of cells of the lymphoid lineage (HP:0012140)2.20937316
97IgG deficiency (HP:0004315)2.20841041
98Granulocytopenia (HP:0001913)2.20762460
99Amaurosis fugax (HP:0100576)2.19870579
100Vasculitis (HP:0002633)2.17208373
101Abnormality of the peritoneum (HP:0002585)2.16448251
102Optic neuritis (HP:0100653)2.15730391
103Retrobulbar optic neuritis (HP:0100654)2.15730391
104Autoimmune hemolytic anemia (HP:0001890)2.14368227
105Increased serum ferritin (HP:0003281)2.14152763
106Hypergammaglobulinemia (HP:0010702)2.11960492
107Severe combined immunodeficiency (HP:0004430)2.11152533
108Neutropenia (HP:0001875)2.11145152
109Gangrene (HP:0100758)2.08819511
110Skin rash (HP:0000988)2.08008287
111Recurrent lower respiratory tract infections (HP:0002783)2.06340092
112Microcytic anemia (HP:0001935)2.04760265
113Verrucae (HP:0200043)2.04439380
114Papilloma (HP:0012740)2.04439380
115Premature loss of primary teeth (HP:0006323)2.04065737
116Poikiloderma (HP:0001029)2.03785032
117Abnormality of eosinophils (HP:0001879)2.03273777
118Leukocytosis (HP:0001974)2.02929184
119Recurrent cutaneous fungal infections (HP:0011370)2.02548968
120Chronic mucocutaneous candidiasis (HP:0002728)2.02548968
121Abnormality of the heme biosynthetic pathway (HP:0010472)2.02411215
122Acute lymphatic leukemia (HP:0006721)2.01494867
123Abnormality of iron homeostasis (HP:0011031)2.00533167
124Purpura (HP:0000979)1.99796545
125Ankle contracture (HP:0006466)1.99180430
126Glomerulopathy (HP:0100820)1.98889396
127Thoracic kyphosis (HP:0002942)1.97898767
128Increased cerebral lipofuscin (HP:0011813)1.97141381
129Acute hepatic failure (HP:0006554)1.96785172
130Abnormal platelet volume (HP:0011876)1.95701422
131Atrophy/Degeneration involving motor neurons (HP:0007373)1.92918194
132Viral hepatitis (HP:0006562)1.91685340
133Thyroiditis (HP:0100646)1.91508803
134Abnormality of the columella (HP:0009929)1.91433872
135Acne (HP:0001061)1.91410159
136Loss of speech (HP:0002371)1.91228335
137Hypoplasia of the thymus (HP:0000778)1.91030481
138Abnormality of the pericardium (HP:0001697)1.90406663
139Muscle fiber atrophy (HP:0100295)1.89438984
140Abnormality of the endocardium (HP:0004306)1.89022554
141Type 2 muscle fiber atrophy (HP:0003554)1.88880146
142Pulmonary fibrosis (HP:0002206)1.88765386
143Hypoproteinemia (HP:0003075)1.88681415
144Pulmonary infiltrates (HP:0002113)1.88570098
145Exertional dyspnea (HP:0002875)1.87327300
146Colon cancer (HP:0003003)1.85973561
147Visual hallucinations (HP:0002367)1.85786822
148Hypermelanotic macule (HP:0001034)1.85426197
149Abnormality of glycolipid metabolism (HP:0010969)1.84621392
150Abnormality of glycosphingolipid metabolism (HP:0004343)1.84621392
151Increased IgE level (HP:0003212)1.84021365
152Keratoconjunctivitis sicca (HP:0001097)1.83519306
153Decreased activity of mitochondrial respiratory chain (HP:0008972)1.81820898

Predicted kinase interactions (KEA)

RankGene SetZ-score
1KIT3.32984326
2PIK3CG3.23089173
3STK162.99954316
4MAP4K12.94956447
5TEC2.74528814
6PIM22.63543333
7BTK2.58838856
8NME22.58681422
9EEF2K2.46495737
10WEE12.46204853
11TNIK2.39067409
12CSK2.38440975
13FLT32.21808311
14MAP3K122.15780991
15PRPF4B2.15227931
16BLK2.07547886
17EPHB11.94307657
18IRAK41.90167200
19CDC71.84759398
20VRK11.83101420
21TAOK11.72238454
22ZAP701.64878291
23CDK191.64783562
24TBK11.64510374
25JAK31.63129871
26IKBKE1.57278032
27MAP3K31.55924535
28TAOK31.54981304
29CSF1R1.54256049
30FES1.51262100
31MAP2K31.50711952
32FGR1.50338012
33SYK1.48790445
34BRSK21.43136211
35TXK1.41305468
36RPS6KB21.39757363
37PASK1.35111208
38SCYL21.32766574
39DYRK31.31207038
40SIK31.28569343
41LRRK21.28245596
42TYK21.23576065
43MAP3K131.23360263
44RPS6KA41.22999259
45TGFBR11.21612174
46DAPK11.21380357
47CLK11.21266630
48MAP3K11.19436432
49CDK71.16602566
50ADRBK21.10648236
51KDR1.09116224
52SMG11.08674797
53PRKD21.07408791
54MATK1.06568331
55BUB11.06146094
56LYN1.04523873
57TRIB31.03974791
58EIF2AK11.03924119
59SIK21.03501371
60ACVR1B1.00253250
61ERN11.00245804
62IKBKB0.99121520
63MAPKAPK30.98738984
64MARK30.97312473
65PIM10.95962739
66ATR0.94778578
67KSR20.93847592
68CDK80.93042052
69MAPKAPK50.92950391
70MARK20.91885899
71LCK0.91744372
72ITK0.91711169
73RIPK40.91688754
74EIF2AK30.91620173
75MAP3K60.90391663
76RAF10.89085610
77GRK60.85483012
78PDK10.85456737
79TAOK20.82869703
80PTK60.77970426
81MAPK40.77454765
82MAPK120.77312901
83CCNB10.74800777
84TLK10.74001167
85MUSK0.73859723
86PDPK10.73810249
87MKNK10.72511298
88IRAK10.70177306
89RPS6KA60.68965049
90PAK40.68409857
91TESK20.67279667
92CAMKK20.66563344
93NEK20.65873160
94MAP3K70.65833989
95HCK0.65231819
96STK100.63743927
97CDK40.63060114
98MYLK0.62571621
99BCKDK0.62524374
100MAP2K40.62390790
101PRKCQ0.60709719
102FYN0.60141397
103BMPR20.59246237
104IRAK20.58943624
105TSSK60.58572844
106BRSK10.58095752
107SRPK10.58055909
108MAP3K80.57039345
109ILK0.56310109
110MAP3K50.55952235
111RPS6KL10.55081563
112RPS6KC10.55081563
113PKN20.54947203
114MAPK110.54935182
115PTK2B0.53108459
116NLK0.52080448
117STK110.51942838
118TRPM70.51792546
119MAP3K110.51445111
120MAPK70.50816754
121PRKG20.49511365
122MAP2K60.48557110
123TGFBR20.48198504
124HIPK20.47861671
125DYRK1B0.45618407
126JAK20.45549608
127MKNK20.44993252
128AURKB0.44870921
129YES10.43725924
130EPHA30.42580824
131CAMK10.42216027
132JAK10.42153292
133RET0.40281901
134CDC42BPA0.39357068
135TNK20.38972156
136IRAK30.37820604
137SIK10.37341320
138STK380.35101453
139FGFR40.34507363
140MAP3K140.32633347
141CDK60.32276960
142CSNK2A20.31855541
143MAPKAPK20.31096396
144FGFR30.28959113
145CAMKK10.27460152
146PRKCH0.27410300
147ALK0.26969827
148MAP2K20.26676792
149PRKCD0.26458690
150RPS6KA20.26175592

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.16878764
2Ribosome_Homo sapiens_hsa030104.51588451
3Mismatch repair_Homo sapiens_hsa034303.62030478
4Base excision repair_Homo sapiens_hsa034102.87237336
5Staphylococcus aureus infection_Homo sapiens_hsa051502.83365526
6Homologous recombination_Homo sapiens_hsa034402.79663068
7Graft-versus-host disease_Homo sapiens_hsa053322.46468214
8Autoimmune thyroid disease_Homo sapiens_hsa053202.34080784
9Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.25194171
10Primary immunodeficiency_Homo sapiens_hsa053402.21293137
11Pyrimidine metabolism_Homo sapiens_hsa002402.10135250
12Nucleotide excision repair_Homo sapiens_hsa034201.96943336
13Spliceosome_Homo sapiens_hsa030401.89976220
14Antigen processing and presentation_Homo sapiens_hsa046121.81460437
15Type I diabetes mellitus_Homo sapiens_hsa049401.81007921
16RNA polymerase_Homo sapiens_hsa030201.78747066
17Leishmaniasis_Homo sapiens_hsa051401.78682148
18Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.74603330
19Non-homologous end-joining_Homo sapiens_hsa034501.74002844
20Viral myocarditis_Homo sapiens_hsa054161.65732642
21Proteasome_Homo sapiens_hsa030501.61134813
22RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.57977854
23Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.55734468
24Measles_Homo sapiens_hsa051621.54322189
25Other glycan degradation_Homo sapiens_hsa005111.53256514
26Pentose phosphate pathway_Homo sapiens_hsa000301.50109753
27B cell receptor signaling pathway_Homo sapiens_hsa046621.49152441
28Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.46339831
29Phagosome_Homo sapiens_hsa041451.42374843
30Herpes simplex infection_Homo sapiens_hsa051681.41234437
31N-Glycan biosynthesis_Homo sapiens_hsa005101.38968872
32Protein export_Homo sapiens_hsa030601.37156788
33Asthma_Homo sapiens_hsa053101.34559913
34One carbon pool by folate_Homo sapiens_hsa006701.33131609
35African trypanosomiasis_Homo sapiens_hsa051431.31306238
36Hematopoietic cell lineage_Homo sapiens_hsa046401.28074823
37Cell cycle_Homo sapiens_hsa041101.27669455
38Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.24277381
39Acute myeloid leukemia_Homo sapiens_hsa052211.22054130
40Legionellosis_Homo sapiens_hsa051341.13684770
41Fanconi anemia pathway_Homo sapiens_hsa034601.13238341
42Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.12868305
43RNA degradation_Homo sapiens_hsa030181.12581352
44Osteoclast differentiation_Homo sapiens_hsa043801.11532832
45Hepatitis C_Homo sapiens_hsa051601.10674272
46Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.09875416
47Purine metabolism_Homo sapiens_hsa002301.09702453
48NF-kappa B signaling pathway_Homo sapiens_hsa040641.05514354
49Transcriptional misregulation in cancer_Homo sapiens_hsa052021.05290671
50Intestinal immune network for IgA production_Homo sapiens_hsa046721.04838598
51Toll-like receptor signaling pathway_Homo sapiens_hsa046201.02236100
52RNA transport_Homo sapiens_hsa030131.02061441
53Jak-STAT signaling pathway_Homo sapiens_hsa046301.01498778
54Pertussis_Homo sapiens_hsa051330.96736172
55Hepatitis B_Homo sapiens_hsa051610.95524799
56Rheumatoid arthritis_Homo sapiens_hsa053230.94090180
57VEGF signaling pathway_Homo sapiens_hsa043700.89779588
58p53 signaling pathway_Homo sapiens_hsa041150.88138147
59Thyroid cancer_Homo sapiens_hsa052160.87863711
60Shigellosis_Homo sapiens_hsa051310.87419372
61Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.86938099
62Platelet activation_Homo sapiens_hsa046110.86341267
63Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.85746035
64Influenza A_Homo sapiens_hsa051640.85518586
65Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.84098978
66SNARE interactions in vesicular transport_Homo sapiens_hsa041300.83913171
67Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.82521851
68Epstein-Barr virus infection_Homo sapiens_hsa051690.80321662
69Endocytosis_Homo sapiens_hsa041440.78614516
70NOD-like receptor signaling pathway_Homo sapiens_hsa046210.78319747
71Systemic lupus erythematosus_Homo sapiens_hsa053220.78319215
72Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.77910014
73Apoptosis_Homo sapiens_hsa042100.75891963
74Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.75869587
75Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.74589462
76Toxoplasmosis_Homo sapiens_hsa051450.74362026
77Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.74103893
78Carbohydrate digestion and absorption_Homo sapiens_hsa049730.70685886
79Sphingolipid signaling pathway_Homo sapiens_hsa040710.70073660
80Folate biosynthesis_Homo sapiens_hsa007900.69568259
81Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.69330826
82Prolactin signaling pathway_Homo sapiens_hsa049170.69112920
83Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.68945538
84Glycosaminoglycan degradation_Homo sapiens_hsa005310.68737812
85Sulfur relay system_Homo sapiens_hsa041220.67954797
86Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.67135013
87Viral carcinogenesis_Homo sapiens_hsa052030.66259996
88* Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.66222427
89Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.65196380
90Tuberculosis_Homo sapiens_hsa051520.64162431
91Drug metabolism - other enzymes_Homo sapiens_hsa009830.61985521
92Non-small cell lung cancer_Homo sapiens_hsa052230.59970446
93Chronic myeloid leukemia_Homo sapiens_hsa052200.59820261
94Salmonella infection_Homo sapiens_hsa051320.59716177
95Adipocytokine signaling pathway_Homo sapiens_hsa049200.59335569
96Phospholipase D signaling pathway_Homo sapiens_hsa040720.59305929
97Galactose metabolism_Homo sapiens_hsa000520.59150178
98Renal cell carcinoma_Homo sapiens_hsa052110.59084399
99Allograft rejection_Homo sapiens_hsa053300.59059254
100Notch signaling pathway_Homo sapiens_hsa043300.57844342
101Malaria_Homo sapiens_hsa051440.55674541
102Phosphatidylinositol signaling system_Homo sapiens_hsa040700.54978498
103Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.53934307
104Glycerophospholipid metabolism_Homo sapiens_hsa005640.53395157
105T cell receptor signaling pathway_Homo sapiens_hsa046600.53145158
106AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.52821585
107Small cell lung cancer_Homo sapiens_hsa052220.52740771
108Leukocyte transendothelial migration_Homo sapiens_hsa046700.52666381
109Regulation of autophagy_Homo sapiens_hsa041400.52291277
110Amoebiasis_Homo sapiens_hsa051460.50570685
111Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.50187114
112Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.49685518
113Colorectal cancer_Homo sapiens_hsa052100.49569657
114Basal transcription factors_Homo sapiens_hsa030220.49379786
115FoxO signaling pathway_Homo sapiens_hsa040680.48733546
116Choline metabolism in cancer_Homo sapiens_hsa052310.46535728
117Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.45614849
118Inositol phosphate metabolism_Homo sapiens_hsa005620.44662597
119Endometrial cancer_Homo sapiens_hsa052130.43947100
120Renin-angiotensin system_Homo sapiens_hsa046140.43889452
121Caffeine metabolism_Homo sapiens_hsa002320.43746885
122GnRH signaling pathway_Homo sapiens_hsa049120.43552808
123HTLV-I infection_Homo sapiens_hsa051660.42792364
124Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.41643755
125Chemokine signaling pathway_Homo sapiens_hsa040620.41552617
126mTOR signaling pathway_Homo sapiens_hsa041500.41338460
127MAPK signaling pathway_Homo sapiens_hsa040100.39683317
128Insulin resistance_Homo sapiens_hsa049310.39070342
129Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.39001922
130Pancreatic cancer_Homo sapiens_hsa052120.38604537
131HIF-1 signaling pathway_Homo sapiens_hsa040660.38344502
132Neurotrophin signaling pathway_Homo sapiens_hsa047220.36946680
133Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.36925568
134TNF signaling pathway_Homo sapiens_hsa046680.36412839
135Pentose and glucuronate interconversions_Homo sapiens_hsa000400.36047802
136Glutathione metabolism_Homo sapiens_hsa004800.35274237
137Cysteine and methionine metabolism_Homo sapiens_hsa002700.34789130
138Rap1 signaling pathway_Homo sapiens_hsa040150.32834770
139Central carbon metabolism in cancer_Homo sapiens_hsa052300.32789923
140Cyanoamino acid metabolism_Homo sapiens_hsa004600.32598432
141Lysosome_Homo sapiens_hsa041420.32085112
142Type II diabetes mellitus_Homo sapiens_hsa049300.31880319
143Regulation of actin cytoskeleton_Homo sapiens_hsa048100.26744261
144Collecting duct acid secretion_Homo sapiens_hsa049660.25749007
145ErbB signaling pathway_Homo sapiens_hsa040120.23658385

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