FZD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1collagen fibril organization (GO:0030199)4.90405678
2regulation of cardioblast differentiation (GO:0051890)4.66607289
3bone trabecula formation (GO:0060346)4.62881010
4protein heterotrimerization (GO:0070208)4.55527117
5chondrocyte proliferation (GO:0035988)4.54419142
6mesenchymal-epithelial cell signaling (GO:0060638)4.45214303
7sequestering of extracellular ligand from receptor (GO:0035581)4.38303140
8axon extension involved in axon guidance (GO:0048846)4.28358456
9neuron projection extension involved in neuron projection guidance (GO:1902284)4.28358456
10* planar cell polarity pathway involved in neural tube closure (GO:0090179)4.03495882
11* G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.78818322
12* regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.77371350
13skin morphogenesis (GO:0043589)3.74965457
14craniofacial suture morphogenesis (GO:0097094)3.68640511
15negative regulation of chondrocyte differentiation (GO:0032331)3.67442905
16lateral sprouting from an epithelium (GO:0060601)3.66565831
17endodermal cell differentiation (GO:0035987)3.58370433
18outer ear morphogenesis (GO:0042473)3.56966214
19regulation of cardioblast proliferation (GO:0003264)3.54082665
20regulation of secondary heart field cardioblast proliferation (GO:0003266)3.54082665
21chondrocyte development (GO:0002063)3.52653916
22collagen metabolic process (GO:0032963)3.41451624
23negative regulation of cartilage development (GO:0061037)3.38571921
24collagen catabolic process (GO:0030574)3.36147317
25dermatan sulfate biosynthetic process (GO:0030208)3.32426254
26cell proliferation involved in metanephros development (GO:0072203)3.32221748
27regulation of branching involved in salivary gland morphogenesis (GO:0060693)3.26804500
28regulation of branching involved in prostate gland morphogenesis (GO:0060687)3.25123697
29insulin-like growth factor receptor signaling pathway (GO:0048009)3.24692961
30regulation of tight junction assembly (GO:2000810)3.22892161
31multicellular organismal macromolecule metabolic process (GO:0044259)3.22762559
32peripheral nervous system neuron development (GO:0048935)3.20122636
33desmosome organization (GO:0002934)3.18931471
34regulation of transforming growth factor beta2 production (GO:0032909)3.18000623
35cardiac muscle cell proliferation (GO:0060038)3.17361480
36positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr3.16823501
37regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.14859531
38positive regulation of mesenchymal cell proliferation (GO:0002053)3.13598228
39metanephric mesenchyme development (GO:0072075)3.12564062
40embryonic skeletal joint morphogenesis (GO:0060272)3.11262226
41dermatan sulfate metabolic process (GO:0030205)3.10628691
42multicellular organismal catabolic process (GO:0044243)3.07080807
43hippo signaling (GO:0035329)3.06390906
44embryonic cranial skeleton morphogenesis (GO:0048701)3.05755735
45multicellular organismal metabolic process (GO:0044236)3.04416638
46cellular response to vitamin (GO:0071295)3.02491037
47negative regulation of cardiac muscle tissue growth (GO:0055022)3.01234271
48negative regulation of heart growth (GO:0061117)3.01234271
49cranial nerve morphogenesis (GO:0021602)3.01135902
50apoptotic cell clearance (GO:0043277)3.00552725
51cochlea morphogenesis (GO:0090103)2.98864830
52positive regulation of odontogenesis (GO:0042482)2.98114676
53muscle cell proliferation (GO:0033002)2.98057063
54middle ear morphogenesis (GO:0042474)2.97706141
55regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.97001122
56generation of neurons (GO:0048699)2.95596763
57cellular response to vitamin D (GO:0071305)2.95417241
58kidney mesenchyme development (GO:0072074)2.95343204
59positive regulation of gastrulation (GO:2000543)2.95309528
60mesenchyme morphogenesis (GO:0072132)2.94266077
61regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.94179537
62extracellular matrix disassembly (GO:0022617)2.92437908
63regulation of mesenchymal cell proliferation (GO:0010464)2.91463422
64regulation of cartilage development (GO:0061035)2.90933994
65basement membrane organization (GO:0071711)2.90262835
66positive regulation of cartilage development (GO:0061036)2.90195940
67atrial septum morphogenesis (GO:0060413)2.89896460
68convergent extension (GO:0060026)2.89632941
69positive regulation of extracellular matrix organization (GO:1903055)2.89142369
70mesenchymal cell proliferation (GO:0010463)2.88714100
71* Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.88499413
72negative regulation of embryonic development (GO:0045992)2.88368171
73positive regulation of fatty acid beta-oxidation (GO:0032000)2.86706382
74cell proliferation involved in kidney development (GO:0072111)2.86146382
75regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.85650941
76outflow tract septum morphogenesis (GO:0003148)2.85030453
77endocardial cushion morphogenesis (GO:0003203)2.85023887
78prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060522.84414174
79positive regulation of endothelial cell apoptotic process (GO:2000353)2.84180241
80vascular endothelial growth factor signaling pathway (GO:0038084)2.84028181
81epithelial cell-cell adhesion (GO:0090136)2.83608521
82paraxial mesoderm development (GO:0048339)2.83222584
83camera-type eye morphogenesis (GO:0048593)2.82516222
84* non-canonical Wnt signaling pathway (GO:0035567)2.82434347
85fibril organization (GO:0097435)2.82137357
86midgut development (GO:0007494)2.81170133
87branching involved in salivary gland morphogenesis (GO:0060445)2.80891501
88regulation of chondrocyte differentiation (GO:0032330)2.80163853
89dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.79605082
90segment specification (GO:0007379)2.78800291
91* regulation of establishment of planar polarity (GO:0090175)2.78289302
92regulation of axon extension involved in axon guidance (GO:0048841)2.76218720
93regulation of axon guidance (GO:1902667)2.76205397
94striated muscle cell proliferation (GO:0014855)2.76042189
95positive regulation of epithelial to mesenchymal transition (GO:0010718)2.74838056
96cranial suture morphogenesis (GO:0060363)2.74683011
97polarized epithelial cell differentiation (GO:0030859)2.74578190
98regulation of heart morphogenesis (GO:2000826)2.74035389
99axon extension (GO:0048675)2.73735682
100muscle cell migration (GO:0014812)2.71423802
101nephron tubule formation (GO:0072079)2.71337094
102atrioventricular valve morphogenesis (GO:0003181)2.70382962
103regulation of organ formation (GO:0003156)2.70373620
104aorta morphogenesis (GO:0035909)2.70136409
105eye morphogenesis (GO:0048592)2.69860190
106glomerular basement membrane development (GO:0032836)2.69423812
107cell migration involved in heart development (GO:0060973)2.68953471
108endothelial cell morphogenesis (GO:0001886)2.67758030
109negative regulation of fatty acid transport (GO:2000192)2.66949982
110cell adhesion mediated by integrin (GO:0033627)2.66013180
111anatomical structure regression (GO:0060033)2.65915330
112hemidesmosome assembly (GO:0031581)2.65078742
113glomerular filtration (GO:0003094)2.64967515
114adhesion of symbiont to host cell (GO:0044650)2.64137155
115virion attachment to host cell (GO:0019062)2.64137155
116negative regulation of cell fate specification (GO:0009996)2.63795784
117regulation of cell proliferation involved in heart morphogenesis (GO:2000136)2.62755326
118extracellular matrix assembly (GO:0085029)2.61033206
119keratan sulfate catabolic process (GO:0042340)2.60909675
120cell surface receptor signaling pathway involved in heart development (GO:0061311)2.59182322
121renal filtration (GO:0097205)2.58345168
122protein localization to cell surface (GO:0034394)2.56822108
123negative chemotaxis (GO:0050919)2.56759660
124lymph vessel development (GO:0001945)2.56297360
125glial cell migration (GO:0008347)2.56227795
126semaphorin-plexin signaling pathway (GO:0071526)2.56142038
127cardiac myofibril assembly (GO:0055003)2.55962740
128metanephric tubule development (GO:0072170)2.54438342
129metanephric nephron tubule development (GO:0072234)2.54438342
130pattern specification involved in kidney development (GO:0061004)2.54302816
131endothelial cell chemotaxis (GO:0035767)2.53906611
132mesenchymal cell differentiation involved in renal system development (GO:2001012)2.53528565
133mesenchymal cell differentiation involved in kidney development (GO:0072161)2.53528565
134negative regulation of axon guidance (GO:1902668)2.53511961
135thyroid gland development (GO:0030878)2.53202917
136branching involved in prostate gland morphogenesis (GO:0060442)2.52740609
137myoblast migration (GO:0051451)2.52288984
138proximal/distal pattern formation (GO:0009954)2.52149758
139extracellular negative regulation of signal transduction (GO:1900116)2.51393796
140extracellular regulation of signal transduction (GO:1900115)2.51393796
141ganglion development (GO:0061548)2.51137195
142cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.50843655
143organ induction (GO:0001759)2.50667812
144smooth muscle cell differentiation (GO:0051145)2.49912611
145extracellular fibril organization (GO:0043206)2.49599388
146plasma membrane repair (GO:0001778)2.49382736
147regulation of cell fate specification (GO:0042659)2.48839673
148* negative regulation of catenin import into nucleus (GO:0035414)2.48620098
149collecting duct development (GO:0072044)2.48426026

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human5.39253219
2TRIM28_21343339_ChIP-Seq_HEK293_Human4.21111218
3RARG_19884340_ChIP-ChIP_MEFs_Mouse3.03456101
4TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.49944803
5PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.47493673
6ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.32562813
7* EED_16625203_ChIP-ChIP_MESCs_Mouse2.27086477
8SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.07124787
9* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.06234977
10* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.06234977
11* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.02423430
12EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.00244879
13CLOCK_20551151_ChIP-Seq_293T_Human1.99109493
14* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.97756903
15CDX2_19796622_ChIP-Seq_MESCs_Mouse1.95697110
16CJUN_26792858_Chip-Seq_BT549_Human1.95012484
17EP300_21415370_ChIP-Seq_HL-1_Mouse1.92730695
18* SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.89027015
19* SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.82746853
20NRF2_20460467_ChIP-Seq_MEFs_Mouse1.82144190
21NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.82144190
22* THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.81911072
23NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.79887492
24WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.79653436
25TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.78169993
26* JARID2_20075857_ChIP-Seq_MESCs_Mouse1.76557812
27* EZH2_27304074_Chip-Seq_ESCs_Mouse1.76523519
28AR_21572438_ChIP-Seq_LNCaP_Human1.75938302
29WT1_19549856_ChIP-ChIP_CCG9911_Human1.75063086
30* TP53_20018659_ChIP-ChIP_R1E_Mouse1.74519212
31* TP53_18474530_ChIP-ChIP_U2OS_Human1.74321323
32EZH2_22144423_ChIP-Seq_EOC_Human1.73465296
33ZNF217_24962896_ChIP-Seq_MCF-7_Human1.70726077
34NFIB_24661679_ChIP-Seq_LUNG_Mouse1.70507038
35* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.70063296
36* PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.70037970
37CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.67981507
38RBPJ_22232070_ChIP-Seq_NCS_Mouse1.67911296
39GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.63136109
40SOX9_24532713_ChIP-Seq_HFSC_Mouse1.62857071
41RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.62769519
42RNF2_27304074_Chip-Seq_ESCs_Mouse1.62365116
43CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.62053786
44ESR1_21235772_ChIP-Seq_MCF-7_Human1.57522084
45* JARID2_20064375_ChIP-Seq_MESCs_Mouse1.56148707
46* SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.55887224
47ELK3_25401928_ChIP-Seq_HUVEC_Human1.53632343
48ESR2_21235772_ChIP-Seq_MCF-7_Human1.51285675
49PPAR_26484153_Chip-Seq_NCI-H1993_Human1.46838177
50* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.43227215
51HIF1A_21447827_ChIP-Seq_MCF-7_Human1.42476904
52KDM2B_26808549_Chip-Seq_SUP-B15_Human1.41664580
53EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.41323560
54BRD4_25478319_ChIP-Seq_HGPS_Human1.39000845
55RXR_22108803_ChIP-Seq_LS180_Human1.35179858
56HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.34738466
57* PIAS1_25552417_ChIP-Seq_VCAP_Human1.33222353
58* TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.33166900
59SMAD_19615063_ChIP-ChIP_OVARY_Human1.32949472
60BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.31497995
61* ISL1_27105846_Chip-Seq_CPCs_Mouse1.30368544
62AHR_22903824_ChIP-Seq_MCF-7_Human1.29998897
63TP53_16413492_ChIP-PET_HCT116_Human1.28128775
64ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.25494872
65MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.24583195
66EZH2_27294783_Chip-Seq_ESCs_Mouse1.23605054
67FOXO3_23340844_ChIP-Seq_DLD1_Human1.23483296
68RACK7_27058665_Chip-Seq_MCF-7_Human1.22643081
69BCAT_22108803_ChIP-Seq_LS180_Human1.21810990
70SOX2_20726797_ChIP-Seq_SW620_Human1.21704101
71NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.20527055
72SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.20293482
73SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.20293482
74SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.19534239
75* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.17310033
76KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.17022184
77KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.17022184
78KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.17022184
79WT1_25993318_ChIP-Seq_PODOCYTE_Human1.16950147
80* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.15409743
81* ARNT_22903824_ChIP-Seq_MCF-7_Human1.13198996
82SUZ12_27294783_Chip-Seq_ESCs_Mouse1.13111096
83LXR_22292898_ChIP-Seq_THP-1_Human1.11971748
84TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.11636302
85* RING1B_27294783_Chip-Seq_ESCs_Mouse1.10564591
86PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.09131142
87SA1_22415368_ChIP-Seq_MEFs_Mouse1.08665395
88PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.08174107
89* RING1B_27294783_Chip-Seq_NPCs_Mouse1.07559495
90STAT6_21828071_ChIP-Seq_BEAS2B_Human1.06394182
91TCF4_18268006_ChIP-ChIP_LS174T_Human1.05446647
92SMC3_22415368_ChIP-Seq_MEFs_Mouse1.05437690
93KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.04142356
94OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.03285391
95TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.02481137
96BMI1_23680149_ChIP-Seq_NPCS_Mouse1.01583091
97* CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.01422844
98SALL4_18804426_ChIP-ChIP_XEN_Mouse1.00490795
99ZFP281_18757296_ChIP-ChIP_E14_Mouse1.00426803
100DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.00337176
101P300_27058665_Chip-Seq_ZR-75-30cells_Human1.00328277
102SMC1_22415368_ChIP-Seq_MEFs_Mouse0.99656002
103* UBF1/2_26484160_Chip-Seq_HMECs_Human0.98397581
104CBX2_27304074_Chip-Seq_ESCs_Mouse0.98127063
105TP63_23658742_ChIP-Seq_EP156T_Human0.97699294
106HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.96845528
107SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.95407534
108ERG_21242973_ChIP-ChIP_JURKAT_Human0.94934461
109TBX20_22328084_ChIP-Seq_HEART_Mouse0.94600474
110TBX20_22080862_ChIP-Seq_HEART_Mouse0.94600474
111STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.93781536
112KDM2B_26808549_Chip-Seq_K562_Human0.93725623
113POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.92823479
114ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.92726356
115ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.92273924
116CDX2_20551321_ChIP-Seq_CACO-2_Human0.92137011
117KLF5_25053715_ChIP-Seq_YYC3_Human0.91779448
118* TP53_23651856_ChIP-Seq_MEFs_Mouse0.91039940
119UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.90932732
120KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.90891482
121CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.90705890
122TP53_22127205_ChIP-Seq_IMR90_Human0.90226246
123KDM2B_26808549_Chip-Seq_JURKAT_Human0.89810712
124ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.89235087
125* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.88821216
126ESR1_20079471_ChIP-ChIP_T-47D_Human0.88057114
127ZFP281_27345836_Chip-Seq_ESCs_Mouse0.87153936
128CTNNB1_20460455_ChIP-Seq_HCT116_Human0.86934756

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen6.62499596
2MP0005275_abnormal_skin_tensile5.31190258
3MP0005503_abnormal_tendon_morphology4.58508981
4MP0003705_abnormal_hypodermis_morpholog3.81614530
5MP0009384_cardiac_valve_regurgitation3.21606943
6MP0003279_aneurysm3.07343659
7MP0001958_emphysema2.84744311
8MP0004272_abnormal_basement_membrane2.78686101
9MP0010030_abnormal_orbit_morphology2.55545276
10MP0010234_abnormal_vibrissa_follicle2.51053273
11MP0005508_abnormal_skeleton_morphology2.18781668
12MP0009250_abnormal_appendicular_skeleto2.01934148
13MP0002060_abnormal_skin_morphology1.93813925
14MP0002282_abnormal_trachea_morphology1.92374227
15MP0000579_abnormal_nail_morphology1.88914663
16MP0009053_abnormal_anal_canal1.88690923
17MP0003385_abnormal_body_wall1.87594527
18MP0006054_spinal_hemorrhage1.86330625
19MP0005623_abnormal_meninges_morphology1.85923489
20MP0000566_synostosis1.75196400
21MP0002249_abnormal_larynx_morphology1.72448808
22MP0000751_myopathy1.69774479
23MP0005257_abnormal_intraocular_pressure1.69208965
24MP0003942_abnormal_urinary_system1.67014682
25MP0002108_abnormal_muscle_morphology1.66505072
26MP0000428_abnormal_craniofacial_morphol1.66122143
27MP0000537_abnormal_urethra_morphology1.65512305
28MP0002896_abnormal_bone_mineralization1.64574837
29MP0000049_abnormal_middle_ear1.63581744
30MP0003566_abnormal_cell_adhesion1.59511509
31MP0001299_abnormal_eye_distance/1.59019312
32MP0000534_abnormal_ureter_morphology1.51894995
33MP0009780_abnormal_chondrocyte_physiolo1.51442052
34MP0004084_abnormal_cardiac_muscle1.38050636
35MP0003941_abnormal_skin_development1.35888912
36MP0000163_abnormal_cartilage_morphology1.35615984
37MP0000733_abnormal_muscle_development1.35367406
38MP0005248_abnormal_Harderian_gland1.34753276
39MP0002115_abnormal_skeleton_extremities1.34251964
40MP0004858_abnormal_nervous_system1.34134745
41MP0002796_impaired_skin_barrier1.34006558
42MP0002932_abnormal_joint_morphology1.32099688
43MP0005409_darkened_coat_color1.29835379
44MP0005023_abnormal_wound_healing1.29005200
45MP0003115_abnormal_respiratory_system1.28655443
46MP0000762_abnormal_tongue_morphology1.28554555
47MP0002295_abnormal_pulmonary_circulatio1.27914634
48MP0001348_abnormal_lacrimal_gland1.27658350
49* MP0003755_abnormal_palate_morphology1.24390652
50MP0003091_abnormal_cell_migration1.21376958
51MP0003937_abnormal_limbs/digits/tail_de1.21357477
52MP0010678_abnormal_skin_adnexa1.17409228
53MP0002098_abnormal_vibrissa_morphology1.15534826
54MP0005390_skeleton_phenotype1.14204636
55MP0004134_abnormal_chest_morphology1.13024342
56MP0001849_ear_inflammation1.11698300
57* MP0003935_abnormal_craniofacial_develop1.11614012
58MP0000462_abnormal_digestive_system1.09756064
59MP0001542_abnormal_bone_strength1.08380960
60MP0002109_abnormal_limb_morphology1.08005185
61MP0002168_other_aberrant_phenotype1.07288524
62MP0001243_abnormal_dermal_layer1.06386478
63MP0005367_renal/urinary_system_phenotyp1.05771547
64MP0000516_abnormal_urinary_system1.05771547
65MP0003938_abnormal_ear_development1.05491779
66* MP0002116_abnormal_craniofacial_bone1.05244376
67MP0000767_abnormal_smooth_muscle1.05139588
68MP0002233_abnormal_nose_morphology1.04460189
69MP0009379_abnormal_foot_pigmentation1.03303532
70MP0005076_abnormal_cell_differentiation1.01744416
71MP0000613_abnormal_salivary_gland1.00512883
72* MP0000432_abnormal_head_morphology0.99592671
73MP0010352_gastrointestinal_tract_polyps0.99453848
74MP0003252_abnormal_bile_duct0.99434578
75MP0002113_abnormal_skeleton_development0.99060023
76MP0002998_abnormal_bone_remodeling0.98820753
77MP0003283_abnormal_digestive_organ0.97771039
78MP0001346_abnormal_lacrimal_gland0.97180372
79MP0010368_abnormal_lymphatic_system0.96993379
80MP0008789_abnormal_olfactory_epithelium0.96581033
81MP0002114_abnormal_axial_skeleton0.96211248
82MP0000383_abnormal_hair_follicle0.95381421
83MP0000647_abnormal_sebaceous_gland0.93252295
84MP0002938_white_spotting0.92644765
85MP0005187_abnormal_penis_morphology0.91083253
86MP0001177_atelectasis0.88908501
87MP0002089_abnormal_postnatal_growth/wei0.88537702
88MP0000759_abnormal_skeletal_muscle0.88493591
89MP0000377_abnormal_hair_follicle0.87977678
90MP0005595_abnormal_vascular_smooth0.87370332
91MP0006138_congestive_heart_failure0.86973527
92MP0005058_abnormal_lysosome_morphology0.85798242
93MP0010771_integument_phenotype0.84697868
94MP0001340_abnormal_eyelid_morphology0.84391390
95MP0002111_abnormal_tail_morphology0.84197636
96MP0003045_fibrosis0.84049219
97MP0005501_abnormal_skin_physiology0.80888589
98MP0002877_abnormal_melanocyte_morpholog0.80791528
99MP0005193_abnormal_anterior_eye0.79433321
100MP0004087_abnormal_muscle_fiber0.78395490
101MP0000013_abnormal_adipose_tissue0.78257287
102MP0000750_abnormal_muscle_regeneration0.78081617
103MP0003300_gastrointestinal_ulcer0.77794378
104MP0001270_distended_abdomen0.77442020
105* MP0001614_abnormal_blood_vessel0.77090750
106MP0002925_abnormal_cardiovascular_devel0.76787495
107MP0010630_abnormal_cardiac_muscle0.76387154
108MP0002177_abnormal_outer_ear0.75511895
109MP0005197_abnormal_uvea_morphology0.74698751
110MP0001879_abnormal_lymphatic_vessel0.73743917
111MP0002697_abnormal_eye_size0.73739031
112MP0005171_absent_coat_pigmentation0.72678827
113MP0003453_abnormal_keratinocyte_physiol0.70833425
114MP0002138_abnormal_hepatobiliary_system0.70692641
115MP0002254_reproductive_system_inflammat0.70465743
116MP0002128_abnormal_blood_circulation0.69535395
117MP0000681_abnormal_thyroid_gland0.67618398
118MP0001175_abnormal_lung_morphology0.67006588
119MP0002972_abnormal_cardiac_muscle0.66517830
120MP0000467_abnormal_esophagus_morphology0.66082319
121MP0005330_cardiomyopathy0.65691829
122MP0002133_abnormal_respiratory_system0.65663327
123MP0005388_respiratory_system_phenotype0.65663327
124MP0001915_intracranial_hemorrhage0.65594624
125MP0003634_abnormal_glial_cell0.64595041
126MP0003795_abnormal_bone_structure0.64408097
127MP0003119_abnormal_digestive_system0.63783900
128MP0001286_abnormal_eye_development0.63356599
129MP0004036_abnormal_muscle_relaxation0.62468036
130MP0003950_abnormal_plasma_membrane0.60572332

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)6.32423534
2Premature rupture of membranes (HP:0001788)5.76639509
3Shallow orbits (HP:0000586)4.85067038
4Broad metatarsal (HP:0001783)4.78362611
5Ankle contracture (HP:0006466)4.18832280
6Aortic dissection (HP:0002647)4.15869326
7Atrophic scars (HP:0001075)4.02552329
8Short 4th metacarpal (HP:0010044)3.75944744
9Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.75944744
10Follicular hyperkeratosis (HP:0007502)3.73914249
11Neonatal short-limb short stature (HP:0008921)3.67773900
12Soft skin (HP:0000977)3.55486362
13Aortic aneurysm (HP:0004942)3.38401411
14Peritonitis (HP:0002586)3.37130990
15Cervical subluxation (HP:0003308)3.26578133
16Aplasia involving bones of the upper limbs (HP:0009823)3.23488697
17Aplasia of the phalanges of the hand (HP:0009802)3.23488697
18Aplasia involving bones of the extremities (HP:0009825)3.23488697
19Cerebral aneurysm (HP:0004944)3.17102249
20Fragile skin (HP:0001030)3.14455183
21Bladder diverticulum (HP:0000015)3.12273248
22Dilatation of the ascending aorta (HP:0005111)2.92444820
23Abnormality of the 4th metacarpal (HP:0010012)2.91460078
24Abnormality of dentin (HP:0010299)2.89617394
25Mitral valve prolapse (HP:0001634)2.80601380
26Type 1 muscle fiber predominance (HP:0003803)2.80007788
27Coronal craniosynostosis (HP:0004440)2.78411082
28Blue sclerae (HP:0000592)2.77008811
29Genu recurvatum (HP:0002816)2.74145322
30Wide anterior fontanel (HP:0000260)2.65501686
31Vascular tortuosity (HP:0004948)2.53320716
32Spinal rigidity (HP:0003306)2.52480381
33Calcaneovalgus deformity (HP:0001848)2.52368614
34Hyperextensible skin (HP:0000974)2.50362716
35Pulmonary artery stenosis (HP:0004415)2.48950777
36Short hallux (HP:0010109)2.47596691
37Wormian bones (HP:0002645)2.47301598
38Biconcave vertebral bodies (HP:0004586)2.45097433
39Short middle phalanx of the 5th finger (HP:0004220)2.40238983
40Arterial tortuosity (HP:0005116)2.38529907
41Overgrowth (HP:0001548)2.38292055
42Deviation of the hallux (HP:0010051)2.36430348
43Deformed tarsal bones (HP:0008119)2.33382837
44Wrist flexion contracture (HP:0001239)2.30869914
45Aplasia/Hypoplasia of the hallux (HP:0008362)2.25501152
46Vertebral compression fractures (HP:0002953)2.22217692
47Camptodactyly of toe (HP:0001836)2.20540057
48Synostosis involving the elbow (HP:0003938)2.20153391
49Humeroradial synostosis (HP:0003041)2.20153391
50Hallux valgus (HP:0001822)2.19861855
51Slender build (HP:0001533)2.18998129
52Broad long bones (HP:0005622)2.18680758
53Abnormality of the calcaneus (HP:0008364)2.15603185
54Infantile muscular hypotonia (HP:0008947)2.15300108
55Joint laxity (HP:0001388)2.15278732
56Elbow flexion contracture (HP:0002987)2.12769382
57Narrow nasal bridge (HP:0000446)2.11762705
58Bronchomalacia (HP:0002780)2.09138163
59Thin bony cortex (HP:0002753)2.09021702
60Turricephaly (HP:0000262)2.07870024
61Abnormality of the phalanges of the hallux (HP:0010057)2.05314343
62Midline defect of the nose (HP:0004122)2.03951975
63Broad ribs (HP:0000885)2.03681695
64Morphological abnormality of the middle ear (HP:0008609)2.03305803
65Broad toe (HP:0001837)2.01858998
66Tibial bowing (HP:0002982)2.01851650
67Mild short stature (HP:0003502)2.00508270
68Bowel diverticulosis (HP:0005222)1.99960937
69Short nail (HP:0001799)1.99745026
70Mesomelia (HP:0003027)1.98025582
71Osteolytic defects of the phalanges of the hand (HP:0009771)1.96690293
72Osteolytic defects of the hand bones (HP:0009699)1.96690293
73Increased connective tissue (HP:0009025)1.96515762
74Knee flexion contracture (HP:0006380)1.95346037
75Abnormality of the parietal bone (HP:0002696)1.93997623
76Nuclear cataract (HP:0100018)1.93436903
77Bell-shaped thorax (HP:0001591)1.93145841
78Aneurysm (HP:0002617)1.92337280
79Syringomyelia (HP:0003396)1.91266146
80Spinal cord lesions (HP:0100561)1.91266146
81Increased variability in muscle fiber diameter (HP:0003557)1.90373849
82Abnormality of the distal phalanges of the toes (HP:0010182)1.90104327
83Ulnar bowing (HP:0003031)1.90000664
84Buphthalmos (HP:0000557)1.89896690
85Obstructive sleep apnea (HP:0002870)1.89757012
86Natal tooth (HP:0000695)1.89410836
87Ectopia lentis (HP:0001083)1.88896647
88Partial duplication of the phalanx of hand (HP:0009999)1.88401146
89Alopecia of scalp (HP:0002293)1.88045726
90Selective tooth agenesis (HP:0001592)1.87902382
91Mildly elevated creatine phosphokinase (HP:0008180)1.87306347
92Cupped ribs (HP:0000887)1.86926805
93Disproportionate tall stature (HP:0001519)1.86794121
94Broad hallux (HP:0010055)1.83725045
95Spondylolisthesis (HP:0003302)1.83674009
96Joint stiffness (HP:0001387)1.83555955
97Hypoplasia of the iris (HP:0007676)1.80301598
98Lymphangioma (HP:0100764)1.80134546
99Abnormality of the distal phalanx of the thumb (HP:0009617)1.79577674
100Cutaneous syndactyly (HP:0012725)1.79441554
101Abnormality of the acetabulum (HP:0003170)1.78148640
102Long toe (HP:0010511)1.78074687
103Tarsal synostosis (HP:0008368)1.77510129
104Venous abnormality (HP:0002624)1.77493681
105Femoral bowing (HP:0002980)1.77407420
106Abnormality of the middle phalanges of the toes (HP:0010183)1.77275802
107Protruding ear (HP:0000411)1.77159594
108Mitral regurgitation (HP:0001653)1.76983012
109Broad face (HP:0000283)1.76567385
110Delayed cranial suture closure (HP:0000270)1.75967758
111Hyperacusis (HP:0010780)1.75420202
112Abnormal delivery (HP:0001787)1.75350465
113Microglossia (HP:0000171)1.74208773
114Right ventricular cardiomyopathy (HP:0011663)1.73822328
115Limited hip movement (HP:0008800)1.73118047
116Osteoarthritis (HP:0002758)1.72792240
117Advanced eruption of teeth (HP:0006288)1.72019319
118Inguinal hernia (HP:0000023)1.70667136
119Hypoventilation (HP:0002791)1.69922024
120Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.69181650
121Absent frontal sinuses (HP:0002688)1.68131041
122Venous insufficiency (HP:0005293)1.67557356
123Long nose (HP:0003189)1.66973824
124Joint contractures involving the joints of the feet (HP:0100492)1.66148885
125Flexion contracture of toe (HP:0005830)1.66148885
126Cutaneous finger syndactyly (HP:0010554)1.65851887
127Hip contracture (HP:0003273)1.65506727
128Atrial fibrillation (HP:0005110)1.60690199
129Mitral stenosis (HP:0001718)1.60223059
130Shawl scrotum (HP:0000049)1.60190212
131Renal duplication (HP:0000075)1.60148172

Predicted kinase interactions (KEA)

RankGene SetZ-score
1DDR24.76851100
2TRIB33.72542800
3SIK13.67502809
4PDGFRA3.65378843
5EPHB23.61500686
6LATS13.40149553
7EPHA32.91100214
8TTN2.75679244
9FGFR22.64681851
10LATS22.45680746
11RIPK12.33592622
12FER2.30436012
13ERN12.13558251
14MOS1.94376685
15EPHA21.88016086
16BMX1.74389512
17MET1.70280156
18PTK61.63975719
19FGFR11.60962058
20DMPK1.57736213
21PKN21.49721286
22PIK3CA1.45629416
23PTK21.41131230
24CAMK1D1.36889563
25PDGFRB1.32262910
26PAK31.29468839
27ERBB31.27845663
28CDK61.23856886
29MST1R1.23555541
30ROCK11.22766701
31PAK21.21360048
32TGFBR21.20829314
33PRPF4B1.17487997
34LMTK21.16807024
35CAMK1G1.15828776
36FRK1.15516140
37RPS6KC11.15462681
38RPS6KL11.15462681
39PRKD21.15264469
40STK31.15173571
41MAP3K61.09615149
42FGFR41.06269940
43TRPM71.04991353
44FGFR30.99751181
45MAPK150.98851665
46TESK10.98392222
47MAP3K100.98078725
48LRRK20.97503928
49NTRK10.95935292
50RPS6KA60.93903627
51SMG10.91628709
52AKT30.90520657
53MTOR0.87408937
54PAK40.85908286
55ERBB20.84483169
56ERBB40.83885773
57BCR0.81132647
58MKNK20.79579740
59ROCK20.78231422
60MYLK0.76770047
61EPHB10.74259745
62MKNK10.73533416
63STK38L0.71970835
64NEK60.71706302
65MARK20.69554788
66JAK10.68351491
67KSR10.68013978
68ILK0.65709181
69DYRK1B0.64943625
70STK240.63367414
71NEK90.63083739
72PRKD10.62596818
73PRKCE0.60989969
74INSR0.60681300
75MAP3K20.58998957
76ICK0.58872101
77MAPK70.58482305
78MAPK120.57669160
79PTK2B0.56013371
80EEF2K0.55477871
81MARK10.55451864
82PRKCH0.55139173
83PRKD30.54958589
84NUAK10.54677257
85TYRO30.54217987
86RET0.54004247
87MELK0.53583389
88GSK3A0.53532030
89SRC0.53234417
90IGF1R0.49851477
91FLT30.47961526
92PNCK0.47862097
93CDC42BPA0.47198975
94ABL20.47014238
95ADRBK10.46922062
96TGFBR10.46113120
97WNK10.46093504
98PLK20.43055366
99NTRK20.42166525
100MAP2K10.42082477
101PAK60.41904149
102STK380.39448381
103PBK0.38866345
104GRK70.38520603
105CHUK0.38338992
106RPS6KA40.37338020
107MAP3K80.35951645
108MAP3K30.35536639
109NLK0.34153512
110PHKG10.34141774
111PHKG20.34141774
112LIMK10.33944867
113IRAK30.33672314
114DAPK30.33502583
115HIPK20.33485806
116MAP3K70.32070337
117TAOK20.31875458
118CDK120.29738384
119SGK30.28911343
120BRD40.28516550
121CLK10.28435614
122CAMK40.28261781
123MAPK10.27842208
124CDK150.26102445
125KSR20.25533277
126MAPK40.24566866
127FYN0.24541105
128RPS6KA20.24155629
129JAK30.23452554
130EGFR0.22850993
131AKT20.21689812
132PRKCG0.20559861

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045123.63749601
2* Basal cell carcinoma_Homo sapiens_hsa052172.81053802
3Focal adhesion_Homo sapiens_hsa045102.46360120
4* Proteoglycans in cancer_Homo sapiens_hsa052052.23896828
5Hedgehog signaling pathway_Homo sapiens_hsa043402.23208973
6Protein digestion and absorption_Homo sapiens_hsa049742.19194197
7Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.02270163
8TGF-beta signaling pathway_Homo sapiens_hsa043501.92581124
9Amoebiasis_Homo sapiens_hsa051461.92324117
10Malaria_Homo sapiens_hsa051441.91074659
11Adherens junction_Homo sapiens_hsa045201.90790415
12* Hippo signaling pathway_Homo sapiens_hsa043901.87153229
13AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.83907110
14Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.77326170
15Small cell lung cancer_Homo sapiens_hsa052221.69228443
16Bladder cancer_Homo sapiens_hsa052191.55934359
17Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.53248030
18MicroRNAs in cancer_Homo sapiens_hsa052061.50694655
19Melanoma_Homo sapiens_hsa052181.50531974
20Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.45408309
21* Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.44228656
22Dilated cardiomyopathy_Homo sapiens_hsa054141.43612016
23Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.41221606
24Other glycan degradation_Homo sapiens_hsa005111.36357633
25Axon guidance_Homo sapiens_hsa043601.31225989
26PI3K-Akt signaling pathway_Homo sapiens_hsa041511.27612635
27Chronic myeloid leukemia_Homo sapiens_hsa052201.26278398
28* Wnt signaling pathway_Homo sapiens_hsa043101.23546229
29* Pathways in cancer_Homo sapiens_hsa052001.12345557
30Nitrogen metabolism_Homo sapiens_hsa009101.10409976
31Glioma_Homo sapiens_hsa052141.10052367
32Thyroid cancer_Homo sapiens_hsa052161.09755988
33Prostate cancer_Homo sapiens_hsa052151.09273588
34Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.08719279
35Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.07074874
36Lysine degradation_Homo sapiens_hsa003101.06553299
37* Melanogenesis_Homo sapiens_hsa049161.06486765
38Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.03997554
39Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.98007904
40Regulation of actin cytoskeleton_Homo sapiens_hsa048100.97590127
41Notch signaling pathway_Homo sapiens_hsa043300.96875551
42Rap1 signaling pathway_Homo sapiens_hsa040150.94708047
43Renin secretion_Homo sapiens_hsa049240.93991894
44Endometrial cancer_Homo sapiens_hsa052130.92882770
45Pancreatic cancer_Homo sapiens_hsa052120.88158056
46Leukocyte transendothelial migration_Homo sapiens_hsa046700.86788913
47Tight junction_Homo sapiens_hsa045300.83882485
48Toxoplasmosis_Homo sapiens_hsa051450.83422698
49TNF signaling pathway_Homo sapiens_hsa046680.83191972
50Thyroid hormone signaling pathway_Homo sapiens_hsa049190.83118585
51Dorso-ventral axis formation_Homo sapiens_hsa043200.81725941
52Viral myocarditis_Homo sapiens_hsa054160.81435815
53Complement and coagulation cascades_Homo sapiens_hsa046100.81048707
54Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.79689064
55Glycosaminoglycan degradation_Homo sapiens_hsa005310.79451944
56Gap junction_Homo sapiens_hsa045400.78515964
57Mineral absorption_Homo sapiens_hsa049780.77127983
58Insulin resistance_Homo sapiens_hsa049310.75161789
59PPAR signaling pathway_Homo sapiens_hsa033200.74524223
60Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.73274196
61Cocaine addiction_Homo sapiens_hsa050300.72659496
62Aldosterone synthesis and secretion_Homo sapiens_hsa049250.72200331
63Central carbon metabolism in cancer_Homo sapiens_hsa052300.72011042
64Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.68579605
65Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.68510147
66VEGF signaling pathway_Homo sapiens_hsa043700.68003351
67Renal cell carcinoma_Homo sapiens_hsa052110.67755892
68Platelet activation_Homo sapiens_hsa046110.66846528
69Choline metabolism in cancer_Homo sapiens_hsa052310.66058925
70Colorectal cancer_Homo sapiens_hsa052100.64705075
71Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.63334180
72Lysosome_Homo sapiens_hsa041420.62741470
73Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.61582639
74Adipocytokine signaling pathway_Homo sapiens_hsa049200.61347946
75ErbB signaling pathway_Homo sapiens_hsa040120.60919774
76* HTLV-I infection_Homo sapiens_hsa051660.59271503
77Bile secretion_Homo sapiens_hsa049760.59265734
78Estrogen signaling pathway_Homo sapiens_hsa049150.58324520
79Ras signaling pathway_Homo sapiens_hsa040140.58183214
80Fatty acid degradation_Homo sapiens_hsa000710.57985956
81Prolactin signaling pathway_Homo sapiens_hsa049170.57901394
82cAMP signaling pathway_Homo sapiens_hsa040240.57631563
83Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.57081980
84Fatty acid metabolism_Homo sapiens_hsa012120.56669322
85Thyroid hormone synthesis_Homo sapiens_hsa049180.56061422
86Phospholipase D signaling pathway_Homo sapiens_hsa040720.55407412
87Non-small cell lung cancer_Homo sapiens_hsa052230.54451584
88Phagosome_Homo sapiens_hsa041450.53270675
89Pertussis_Homo sapiens_hsa051330.52918504
90Fatty acid biosynthesis_Homo sapiens_hsa000610.52441243
91Longevity regulating pathway - mammal_Homo sapiens_hsa042110.52308483
92mTOR signaling pathway_Homo sapiens_hsa041500.51937703
93AMPK signaling pathway_Homo sapiens_hsa041520.51788427
94FoxO signaling pathway_Homo sapiens_hsa040680.51426919
95Cyanoamino acid metabolism_Homo sapiens_hsa004600.51141748
96Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.50387393
97Acute myeloid leukemia_Homo sapiens_hsa052210.48231693
98Insulin signaling pathway_Homo sapiens_hsa049100.48021739
99Prion diseases_Homo sapiens_hsa050200.47419846
100Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.46657333
101Vibrio cholerae infection_Homo sapiens_hsa051100.45936642
102Sulfur metabolism_Homo sapiens_hsa009200.45129858
103cGMP-PKG signaling pathway_Homo sapiens_hsa040220.45081268
104Vascular smooth muscle contraction_Homo sapiens_hsa042700.45052429
105Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.44799912
106Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.44748703
107GnRH signaling pathway_Homo sapiens_hsa049120.44645275
108Osteoclast differentiation_Homo sapiens_hsa043800.44213256
109Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.43842463
110Renin-angiotensin system_Homo sapiens_hsa046140.42553574
111Gastric acid secretion_Homo sapiens_hsa049710.41896110
112Hepatitis B_Homo sapiens_hsa051610.41693895
113Neurotrophin signaling pathway_Homo sapiens_hsa047220.41332261
114Endocytosis_Homo sapiens_hsa041440.41308302
115Oxytocin signaling pathway_Homo sapiens_hsa049210.40266969
116Sphingolipid metabolism_Homo sapiens_hsa006000.39913905
117Salmonella infection_Homo sapiens_hsa051320.37237822
118Tuberculosis_Homo sapiens_hsa051520.36604743
119MAPK signaling pathway_Homo sapiens_hsa040100.35688098
120Toll-like receptor signaling pathway_Homo sapiens_hsa046200.35432914
121Ovarian steroidogenesis_Homo sapiens_hsa049130.35285722

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