G3BP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1establishment of integrated proviral latency (GO:0075713)4.79812844
2paraxial mesoderm development (GO:0048339)3.92808731
3mitotic metaphase plate congression (GO:0007080)3.83684808
4pre-miRNA processing (GO:0031054)3.78632141
5regulation of translational termination (GO:0006449)3.62968822
6regulation of short-term neuronal synaptic plasticity (GO:0048172)3.54059533
7cellular protein complex localization (GO:0034629)3.52974579
8nuclear pore organization (GO:0006999)3.46278177
9ribosome assembly (GO:0042255)3.45914345
10establishment of viral latency (GO:0019043)3.35045003
11positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.33618101
12regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.32042843
13negative regulation of histone methylation (GO:0031061)3.29980647
14nuclear pore complex assembly (GO:0051292)3.28588985
15peptidyl-arginine omega-N-methylation (GO:0035247)3.22708027
16metaphase plate congression (GO:0051310)3.19051167
17peptidyl-arginine N-methylation (GO:0035246)3.18649195
18peptidyl-arginine methylation (GO:0018216)3.18649195
19histone arginine methylation (GO:0034969)3.17514175
20protein localization to kinetochore (GO:0034501)3.12309929
21mitotic sister chromatid segregation (GO:0000070)3.11672390
22heterochromatin organization (GO:0070828)3.10396447
23positive regulation of chromosome segregation (GO:0051984)3.07764355
24nucleobase biosynthetic process (GO:0046112)3.07173871
25DNA replication-dependent nucleosome assembly (GO:0006335)3.06403797
26DNA replication-dependent nucleosome organization (GO:0034723)3.06403797
27purine nucleobase biosynthetic process (GO:0009113)3.06262248
28negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.05394983
29NLS-bearing protein import into nucleus (GO:0006607)3.03885656
30non-recombinational repair (GO:0000726)3.03648483
31double-strand break repair via nonhomologous end joining (GO:0006303)3.03648483
32regulation of posttranscriptional gene silencing (GO:0060147)3.00655633
33regulation of gene silencing by miRNA (GO:0060964)3.00655633
34regulation of gene silencing by RNA (GO:0060966)3.00655633
35RNA stabilization (GO:0043489)2.99883642
36mRNA stabilization (GO:0048255)2.99883642
37regulation of helicase activity (GO:0051095)2.97220969
38regulation of centriole replication (GO:0046599)2.94329187
39synaptic vesicle exocytosis (GO:0016079)2.93703288
40mitotic chromosome condensation (GO:0007076)2.93627010
41regulation of nucleobase-containing compound transport (GO:0032239)2.92631184
42mitotic nuclear envelope disassembly (GO:0007077)2.92178355
43establishment of chromosome localization (GO:0051303)2.91588684
44establishment of protein localization to mitochondrial membrane (GO:0090151)2.90271131
45positive regulation of synapse maturation (GO:0090129)2.89937202
46layer formation in cerebral cortex (GO:0021819)2.89851868
47nuclear envelope disassembly (GO:0051081)2.89588134
48membrane disassembly (GO:0030397)2.89588134
49sister chromatid segregation (GO:0000819)2.89475964
50spindle checkpoint (GO:0031577)2.87103900
51Golgi transport vesicle coating (GO:0048200)2.86755722
52COPI coating of Golgi vesicle (GO:0048205)2.86755722
53regulation of chromosome segregation (GO:0051983)2.85255739
54histone H2A monoubiquitination (GO:0035518)2.84919786
55regulation of spindle organization (GO:0090224)2.83625332
56DNA duplex unwinding (GO:0032508)2.83357624
57mitotic spindle checkpoint (GO:0071174)2.82768702
58regulation of centrosome cycle (GO:0046605)2.82594617
59IMP metabolic process (GO:0046040)2.81974112
60negative regulation of mRNA processing (GO:0050686)2.81611366
61regulation of translational fidelity (GO:0006450)2.80892651
62ATP-dependent chromatin remodeling (GO:0043044)2.80433515
63negative regulation of fibroblast apoptotic process (GO:2000270)2.79505043
64DNA unwinding involved in DNA replication (GO:0006268)2.79275622
65regulation of sister chromatid cohesion (GO:0007063)2.79245807
66synaptic vesicle maturation (GO:0016188)2.78411694
67positive regulation of SMAD protein import into nucleus (GO:0060391)2.78102782
68negative regulation of mRNA metabolic process (GO:1903312)2.77918923
69negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.76677069
70negative regulation of chromosome segregation (GO:0051985)2.76276305
71IMP biosynthetic process (GO:0006188)2.75890817
72negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.75815319
73negative regulation of sister chromatid segregation (GO:0033046)2.75815319
74negative regulation of mitotic sister chromatid separation (GO:2000816)2.75815319
75negative regulation of mitotic sister chromatid segregation (GO:0033048)2.75815319
76mitotic sister chromatid cohesion (GO:0007064)2.75778247
77mitotic spindle assembly checkpoint (GO:0007094)2.75319886
78positive regulation of dendritic spine morphogenesis (GO:0061003)2.74858101
79negative regulation of DNA recombination (GO:0045910)2.73344313
80regulation of NFAT protein import into nucleus (GO:0051532)2.73132258
81regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.72913232
82DNA replication initiation (GO:0006270)2.72221071
83regulation of mitotic metaphase/anaphase transition (GO:0030071)2.72164358
84DNA geometric change (GO:0032392)2.71009700
85regulation of sister chromatid segregation (GO:0033045)2.70841996
86regulation of mitotic sister chromatid separation (GO:0010965)2.70841996
87regulation of mitotic sister chromatid segregation (GO:0033047)2.70841996
88cytoplasmic mRNA processing body assembly (GO:0033962)2.70157603
89spindle assembly checkpoint (GO:0071173)2.70012235
90histone exchange (GO:0043486)2.69091524
91positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.68956147
92positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.68956147
93positive regulation of mitotic sister chromatid separation (GO:1901970)2.68956147
94DNA replication checkpoint (GO:0000076)2.68558390
95regulation of synaptic vesicle exocytosis (GO:2000300)2.68069771
96protein export from nucleus (GO:0006611)2.67775373
97cell fate commitment involved in formation of primary germ layer (GO:0060795)2.67693466
98glucocorticoid receptor signaling pathway (GO:0042921)2.67378073
99chromatin remodeling at centromere (GO:0031055)2.66142592
100regulation of mRNA stability (GO:0043488)2.65600914
101attachment of spindle microtubules to kinetochore (GO:0008608)2.64337630
102spliceosomal tri-snRNP complex assembly (GO:0000244)2.63900083
103protein-DNA complex disassembly (GO:0032986)2.62662453
104nucleosome disassembly (GO:0006337)2.62662453
105DNA topological change (GO:0006265)2.61504549
106neuron cell-cell adhesion (GO:0007158)2.60644575
107somatic diversification of immune receptors via somatic mutation (GO:0002566)2.60475583
108somatic hypermutation of immunoglobulin genes (GO:0016446)2.60475583
109DNA replication-independent nucleosome assembly (GO:0006336)2.60105826
110DNA replication-independent nucleosome organization (GO:0034724)2.60105826
111regulation of DNA methylation (GO:0044030)2.57904045
112regulation of cell fate specification (GO:0042659)2.56423034
113CENP-A containing nucleosome assembly (GO:0034080)2.55627320
114vocalization behavior (GO:0071625)2.54259820
115regulation of meiosis I (GO:0060631)2.54078523
116negative regulation of meiosis (GO:0045835)2.53294630
117COPII vesicle coating (GO:0048208)2.53118030
118negative regulation of microtubule polymerization (GO:0031115)2.52862958
119cell migration in hindbrain (GO:0021535)2.52205428
120glutamate secretion (GO:0014047)2.49696260
121protein localization to chromosome, centromeric region (GO:0071459)2.48708835
122regulation of DNA damage checkpoint (GO:2000001)2.48592592
123regulation of mitotic spindle organization (GO:0060236)2.48339553
124positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.48273518
125ribosome biogenesis (GO:0042254)2.47727542
126protein localization to microtubule (GO:0035372)2.47378086
127protein complex localization (GO:0031503)2.46469339
128locomotory exploration behavior (GO:0035641)2.46423680
129vesicle coating (GO:0006901)2.45634222
130regulation of cofactor metabolic process (GO:0051193)2.44806206
131regulation of coenzyme metabolic process (GO:0051196)2.44806206
132regulation of chromatin silencing (GO:0031935)2.44308602
133mRNA polyadenylation (GO:0006378)2.44276100
134regulation of histone H3-K27 methylation (GO:0061085)2.44062388
135histone H2A ubiquitination (GO:0033522)2.43204395
136regulation of cAMP-dependent protein kinase activity (GO:2000479)2.43183237
137cell communication by electrical coupling (GO:0010644)2.42745910
138RNA polyadenylation (GO:0043631)2.42340936
139negative regulation of RNA splicing (GO:0033119)2.41726159
140regulation of RNA export from nucleus (GO:0046831)2.40633915
141* mRNA transport (GO:0051028)2.40457727
142regulation of histone H3-K9 methylation (GO:0051570)2.39929686
143glutamine metabolic process (GO:0006541)2.39877088
144regulation of gene expression by genetic imprinting (GO:0006349)2.38981585
145kinetochore organization (GO:0051383)2.38541648
146synaptic vesicle docking involved in exocytosis (GO:0016081)2.38226855
147chaperone-mediated protein complex assembly (GO:0051131)2.37350142
148regulation of synaptic vesicle transport (GO:1902803)2.37289577
149regulation of gene silencing (GO:0060968)2.37244070
150regulation of telomere maintenance via telomerase (GO:0032210)2.37177907
151pore complex assembly (GO:0046931)2.37177229
152histone H4-K12 acetylation (GO:0043983)2.36812163
153ectodermal placode formation (GO:0060788)2.36269585
154regulation of RNA stability (GO:0043487)2.35773009
155regulation of Rac protein signal transduction (GO:0035020)2.34840706
156positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling2.34305307
157regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 2.34305307
158nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.34152971
159DNA strand elongation involved in DNA replication (GO:0006271)2.34021400

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.74500373
2SALL1_21062744_ChIP-ChIP_HESCs_Human3.79446076
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.61245811
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.05174049
5* KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.02784241
6E2F4_17652178_ChIP-ChIP_JURKAT_Human3.00966930
7MYC_18555785_ChIP-Seq_MESCs_Mouse2.81884451
8WT1_19549856_ChIP-ChIP_CCG9911_Human2.66326242
9* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.49652366
10EZH2_22144423_ChIP-Seq_EOC_Human2.39969092
11NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.36166030
12ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.21790361
13SALL4_18804426_ChIP-ChIP_MESCs_Mouse2.18624921
14NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.14543630
15CLOCK_20551151_ChIP-Seq_293T_Human2.10157368
16POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.05483916
17FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.02760016
18* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.97269647
19RBPJ_22232070_ChIP-Seq_NCS_Mouse1.96979647
20MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.94690115
21POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.93414384
22NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.90890311
23AR_21909140_ChIP-Seq_LNCAP_Human1.87533399
24MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.85456294
25YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.84292746
26NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.82435048
27ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.77270357
28ETS1_20019798_ChIP-Seq_JURKAT_Human1.77063410
29* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.74053968
30* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.70860718
31KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.70634408
32* SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.70221128
33EST1_17652178_ChIP-ChIP_JURKAT_Human1.68790851
34HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.68661359
35CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.67278263
36ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.59980116
37NANOG_18555785_ChIP-Seq_MESCs_Mouse1.59522547
38THAP11_20581084_ChIP-Seq_MESCs_Mouse1.53210034
39MYC_18358816_ChIP-ChIP_MESCs_Mouse1.50565988
40* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.49938288
41CREB1_15753290_ChIP-ChIP_HEK293T_Human1.49489549
42FUS_26573619_Chip-Seq_HEK293_Human1.49284216
43SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.48218113
44E2F1_21310950_ChIP-Seq_MCF-7_Human1.47641339
45KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.45408846
46KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.45408846
47KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.45408846
48WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.44287303
49SOX2_18555785_ChIP-Seq_MESCs_Mouse1.43987846
50CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.43386884
51NANOG_16153702_ChIP-ChIP_HESCs_Human1.41913742
52POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.41617968
53* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.39717084
54PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.39421780
55GABP_17652178_ChIP-ChIP_JURKAT_Human1.39068676
56SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.38636006
57XRN2_22483619_ChIP-Seq_HELA_Human1.36946637
58SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.35227552
59* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.35088521
60SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.34749139
61ELK1_19687146_ChIP-ChIP_HELA_Human1.34149621
62TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.33112688
63NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.32765729
64JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.32759828
65TCF3_18692474_ChIP-Seq_MEFs_Mouse1.32693102
66TCF3_18692474_ChIP-Seq_MESCs_Mouse1.32465580
67REST_21632747_ChIP-Seq_MESCs_Mouse1.31035700
68TAF15_26573619_Chip-Seq_HEK293_Human1.30430661
69NANOG_21062744_ChIP-ChIP_HESCs_Human1.27416087
70CHD1_26751641_Chip-Seq_LNCaP_Human1.27241725
71ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.25578372
72POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.23175435
73ESR1_15608294_ChIP-ChIP_MCF-7_Human1.22690974
74HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.22336486
75CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.21948370
76EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.21724807
77TTF2_22483619_ChIP-Seq_HELA_Human1.21532790
78RARB_27405468_Chip-Seq_BRAIN_Mouse1.21070728
79EGR1_19374776_ChIP-ChIP_THP-1_Human1.20679591
80ZNF274_21170338_ChIP-Seq_K562_Hela1.19165945
81POU3F2_20337985_ChIP-ChIP_501MEL_Human1.19021244
82* SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.19018447
83* SOX17_20123909_ChIP-Seq_XEN_Mouse1.17830178
84HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.17563829
85VDR_23849224_ChIP-Seq_CD4+_Human1.16450793
86DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.14799395
87GATA1_26923725_Chip-Seq_HPCs_Mouse1.14617326
88KDM5A_27292631_Chip-Seq_BREAST_Human1.14290567
89ZFP281_18757296_ChIP-ChIP_E14_Mouse1.14096921
90E2F1_18555785_ChIP-Seq_MESCs_Mouse1.13204579
91YAP1_20516196_ChIP-Seq_MESCs_Mouse1.12865932
92SOX2_16153702_ChIP-ChIP_HESCs_Human1.11870690
93REST_18959480_ChIP-ChIP_MESCs_Mouse1.11774809
94NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.11132669
95TRIM28_19339689_ChIP-ChIP_MESCs_Mouse1.11130501
96* GABP_19822575_ChIP-Seq_HepG2_Human1.10872972
97SALL4_18804426_ChIP-ChIP_XEN_Mouse1.09413094
98PKCTHETA_26484144_Chip-Seq_BREAST_Human1.08324247
99EWS_26573619_Chip-Seq_HEK293_Human1.07109683
100PADI4_21655091_ChIP-ChIP_MCF-7_Human1.06820569
101ZFX_18555785_ChIP-Seq_MESCs_Mouse1.06790616
102RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.05939188
103TP63_19390658_ChIP-ChIP_HaCaT_Human1.04796836
104CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.04043211
105TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.03859947
106PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.03500374
107POU5F1_16153702_ChIP-ChIP_HESCs_Human1.01978652
108* EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.01431148
109REST_19997604_ChIP-ChIP_NEURONS_Mouse1.00855153
110CIITA_25753668_ChIP-Seq_RAJI_Human1.00692483
111SOX9_26525672_Chip-Seq_HEART_Mouse1.00364448
112HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.00209263
113RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.99744013
114CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.98824679
115BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.98470402
116FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.98178142
117KLF4_18555785_ChIP-Seq_MESCs_Mouse0.97047364
118* SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.96860348
119DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.96344166
120SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.95941626
121NANOG_16518401_ChIP-PET_MESCs_Mouse0.95609511
122TBX3_20139965_ChIP-Seq_ESCs_Mouse0.95154031
123TBX3_20139965_ChIP-Seq_MESCs_Mouse0.94953374
124CTBP2_25329375_ChIP-Seq_LNCAP_Human0.94691345
125* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.94353884
126OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.93273699
127RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.93214446
128YY1_21170310_ChIP-Seq_MESCs_Mouse0.93170934
129DCP1A_22483619_ChIP-Seq_HELA_Human0.92324077
130POU5F1_16518401_ChIP-PET_MESCs_Mouse0.91820450
131CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.91470456
132FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.91085594
133FLI1_27457419_Chip-Seq_LIVER_Mouse0.90692387

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity3.73753117
2MP0003123_paternal_imprinting3.25197478
3MP0003693_abnormal_embryo_hatching3.15017643
4MP0003941_abnormal_skin_development3.13380949
5MP0008877_abnormal_DNA_methylation2.92639286
6MP0003880_abnormal_central_pattern2.85788954
7MP0004957_abnormal_blastocyst_morpholog2.78587165
8MP0003111_abnormal_nucleus_morphology2.74674038
9MP0010094_abnormal_chromosome_stability2.62550179
10MP0003635_abnormal_synaptic_transmissio2.46517546
11MP0003121_genomic_imprinting2.38987910
12MP0004270_analgesia2.37690310
13MP0003787_abnormal_imprinting2.34852246
14MP0003077_abnormal_cell_cycle2.17450081
15MP0002063_abnormal_learning/memory/cond1.99940214
16MP0008057_abnormal_DNA_replication1.92625469
17MP0002009_preneoplasia1.84959802
18MP0002734_abnormal_mechanical_nocicepti1.84557648
19MP0003567_abnormal_fetal_cardiomyocyte1.81644244
20MP0002877_abnormal_melanocyte_morpholog1.77679191
21MP0009745_abnormal_behavioral_response1.77539127
22MP0001730_embryonic_growth_arrest1.75897808
23MP0009046_muscle_twitch1.73560045
24MP0002653_abnormal_ependyma_morphology1.72080696
25MP0010234_abnormal_vibrissa_follicle1.69210157
26MP0001299_abnormal_eye_distance/1.69170022
27MP0003122_maternal_imprinting1.68599765
28MP0002064_seizures1.68560470
29MP0003221_abnormal_cardiomyocyte_apopto1.68024833
30MP0001968_abnormal_touch/_nociception1.65270587
31MP0005423_abnormal_somatic_nervous1.63316024
32MP0008058_abnormal_DNA_repair1.62978332
33MP0008932_abnormal_embryonic_tissue1.61452289
34MP0005623_abnormal_meninges_morphology1.60986615
35MP0003718_maternal_effect1.60814463
36MP0002572_abnormal_emotion/affect_behav1.60586613
37MP0003566_abnormal_cell_adhesion1.58966170
38MP0000778_abnormal_nervous_system1.54980461
39MP0001529_abnormal_vocalization1.53999115
40MP0002697_abnormal_eye_size1.52271388
41MP0000350_abnormal_cell_proliferation1.50626384
42MP0003890_abnormal_embryonic-extraembry1.49088909
43MP0001440_abnormal_grooming_behavior1.48970878
44MP0002084_abnormal_developmental_patter1.45722431
45MP0004272_abnormal_basement_membrane1.42173513
46MP0002184_abnormal_innervation1.42133055
47MP0003119_abnormal_digestive_system1.41305764
48MP0002733_abnormal_thermal_nociception1.38181856
49MP0006276_abnormal_autonomic_nervous1.37150951
50MP0001486_abnormal_startle_reflex1.36385253
51MP0002272_abnormal_nervous_system1.35264903
52MP0000537_abnormal_urethra_morphology1.35255124
53MP0002085_abnormal_embryonic_tissue1.32844210
54MP0003861_abnormal_nervous_system1.32730885
55MP0004811_abnormal_neuron_physiology1.30642622
56MP0001697_abnormal_embryo_size1.29754517
57MP0002735_abnormal_chemical_nociception1.27323757
58MP0002822_catalepsy1.27289233
59MP0003315_abnormal_perineum_morphology1.25731073
60MP0005380_embryogenesis_phenotype1.24754814
61MP0001672_abnormal_embryogenesis/_devel1.24754814
62MP0001849_ear_inflammation1.24082395
63MP0001177_atelectasis1.23387390
64MP0005386_behavior/neurological_phenoty1.22932310
65MP0004924_abnormal_behavior1.22932310
66MP0009697_abnormal_copulation1.21142470
67MP0001293_anophthalmia1.20622385
68MP0002152_abnormal_brain_morphology1.18043734
69MP0001970_abnormal_pain_threshold1.17215257
70MP0002736_abnormal_nociception_after1.16337704
71MP0006072_abnormal_retinal_apoptosis1.16150615
72MP0004133_heterotaxia1.15537604
73MP0000955_abnormal_spinal_cord1.14972335
74MP0010352_gastrointestinal_tract_polyps1.13352474
75MP0001915_intracranial_hemorrhage1.10884904
76MP0005187_abnormal_penis_morphology1.10272299
77MP0002067_abnormal_sensory_capabilities1.08972335
78MP0002254_reproductive_system_inflammat1.08229975
79MP0004264_abnormal_extraembryonic_tissu1.07276371
80MP0008007_abnormal_cellular_replicative1.06569322
81MP0002557_abnormal_social/conspecific_i1.06529669
82MP0001501_abnormal_sleep_pattern1.06465311
83MP0003385_abnormal_body_wall1.06379334
84MP0001286_abnormal_eye_development1.05772837
85MP0000428_abnormal_craniofacial_morphol1.05653802
86MP0002080_prenatal_lethality1.05031276
87MP0001188_hyperpigmentation1.04106003
88MP0000579_abnormal_nail_morphology1.01826536
89MP0002210_abnormal_sex_determination1.01149620
90MP0002081_perinatal_lethality1.00895146
91MP0002882_abnormal_neuron_morphology1.00787850
92MP0010307_abnormal_tumor_latency1.00672292
93MP0003984_embryonic_growth_retardation0.99855816
94MP0004885_abnormal_endolymph0.99852195
95MP0002088_abnormal_embryonic_growth/wei0.99512469
96MP0005394_taste/olfaction_phenotype0.97691283
97MP0005499_abnormal_olfactory_system0.97691283
98MP0005248_abnormal_Harderian_gland0.97497814
99MP0003705_abnormal_hypodermis_morpholog0.94139731
100MP0002233_abnormal_nose_morphology0.92177340
101MP0005076_abnormal_cell_differentiation0.92114613
102MP0001145_abnormal_male_reproductive0.91946179
103MP0002066_abnormal_motor_capabilities/c0.91513651
104MP0002086_abnormal_extraembryonic_tissu0.91376873
105MP0001929_abnormal_gametogenesis0.90784333
106MP0003937_abnormal_limbs/digits/tail_de0.89403807
107MP0003115_abnormal_respiratory_system0.88506560
108MP0002092_abnormal_eye_morphology0.88353923
109MP0000653_abnormal_sex_gland0.88138862
110MP0006292_abnormal_olfactory_placode0.87493362
111MP0002102_abnormal_ear_morphology0.87029008
112MP0003283_abnormal_digestive_organ0.86806655
113MP0000569_abnormal_digit_pigmentation0.86714616
114MP0004197_abnormal_fetal_growth/weight/0.86498909
115MP0000432_abnormal_head_morphology0.85163352
116MP0009703_decreased_birth_body0.84815920
117MP0004233_abnormal_muscle_weight0.84396558
118MP0002160_abnormal_reproductive_system0.83973748
119MP0000631_abnormal_neuroendocrine_gland0.83894104
120MP0003935_abnormal_craniofacial_develop0.83893698
121MP0001485_abnormal_pinna_reflex0.83849155
122MP0005621_abnormal_cell_physiology0.83585069
123MP0002909_abnormal_adrenal_gland0.83509512
124MP0001905_abnormal_dopamine_level0.83163430
125MP0005384_cellular_phenotype0.82393962
126MP0002111_abnormal_tail_morphology0.80115267
127MP0004858_abnormal_nervous_system0.79594586
128MP0002796_impaired_skin_barrier0.78444272
129MP0010630_abnormal_cardiac_muscle0.78422024
130MP0003698_abnormal_male_reproductive0.78403349
131MP0009672_abnormal_birth_weight0.77392112
132MP0003632_abnormal_nervous_system0.76967410
133MP0005646_abnormal_pituitary_gland0.76124872
134MP0003329_amyloid_beta_deposits0.75003166
135MP0001340_abnormal_eyelid_morphology0.73168294
136MP0001984_abnormal_olfaction0.72930166
137MP0004185_abnormal_adipocyte_glucose0.72162875
138MP0003755_abnormal_palate_morphology0.72161060
139MP0000313_abnormal_cell_death0.71317195
140MP0008770_decreased_survivor_rate0.70414999
141MP0004084_abnormal_cardiac_muscle0.70310615
142MP0000462_abnormal_digestive_system0.70091153
143MP0005501_abnormal_skin_physiology0.67800085
144MP0002925_abnormal_cardiovascular_devel0.65607928

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the labia minora (HP:0012880)4.85192113
2Birth length less than 3rd percentile (HP:0003561)3.75138311
3Hepatoblastoma (HP:0002884)3.68972176
4Ependymoma (HP:0002888)3.65910222
5Focal motor seizures (HP:0011153)3.46717425
6Abnormality of the astrocytes (HP:0100707)3.03961351
7Astrocytoma (HP:0009592)3.03961351
8Shoulder girdle muscle weakness (HP:0003547)3.00917369
9Spastic diplegia (HP:0001264)2.99003443
10Breast hypoplasia (HP:0003187)2.90705122
11Medulloblastoma (HP:0002885)2.89818878
12Myokymia (HP:0002411)2.84804228
13Amyotrophic lateral sclerosis (HP:0007354)2.84368788
14Focal seizures (HP:0007359)2.83003079
15Abnormality of the lower motor neuron (HP:0002366)2.73632552
16Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.71129546
17Visual hallucinations (HP:0002367)2.67842425
18Nephroblastoma (Wilms tumor) (HP:0002667)2.63593710
19Supernumerary spleens (HP:0009799)2.57346274
20Colon cancer (HP:0003003)2.55468759
21Hypoglycemic seizures (HP:0002173)2.53986431
22Glioma (HP:0009733)2.53743595
23Embryonal renal neoplasm (HP:0011794)2.50369901
24Exercise-induced muscle cramps (HP:0003710)2.47335280
25Atrophy/Degeneration involving motor neurons (HP:0007373)2.46308858
26Cerebral hypomyelination (HP:0006808)2.44728284
27Neoplasm of the oral cavity (HP:0100649)2.43290703
28Thyroid carcinoma (HP:0002890)2.41620532
29Dysmetric saccades (HP:0000641)2.41329931
30Impaired vibration sensation in the lower limbs (HP:0002166)2.37168545
31Termporal pattern (HP:0011008)2.37020791
32Insidious onset (HP:0003587)2.37020791
33Urinary bladder sphincter dysfunction (HP:0002839)2.36021576
34Atonic seizures (HP:0010819)2.35843483
35Patellar aplasia (HP:0006443)2.29828981
36Agnosia (HP:0010524)2.29085730
37Pelvic girdle muscle weakness (HP:0003749)2.28574634
38Transitional cell carcinoma of the bladder (HP:0006740)2.26905372
39Facial hemangioma (HP:0000329)2.21909039
40Rhabdomyosarcoma (HP:0002859)2.21649595
41Papillary thyroid carcinoma (HP:0002895)2.20925033
42Multiple enchondromatosis (HP:0005701)2.20353262
43Curly hair (HP:0002212)2.20248161
44Hereditary nonpolyposis colorectal carcinoma (HP:0006716)2.17547439
45Neuroblastoma (HP:0003006)2.17021614
46Aplasia/Hypoplasia of the patella (HP:0006498)2.16840557
47Uterine leiomyosarcoma (HP:0002891)2.16681136
48Leiomyosarcoma (HP:0100243)2.16681136
49Absent radius (HP:0003974)2.16117855
50Progressive cerebellar ataxia (HP:0002073)2.14285355
51Shawl scrotum (HP:0000049)2.13974091
52Urinary urgency (HP:0000012)2.13964878
53Vertebral arch anomaly (HP:0008438)2.13188484
54Absence seizures (HP:0002121)2.12798999
55Volvulus (HP:0002580)2.11512538
56Aplasia involving forearm bones (HP:0009822)2.10153771
57Absent forearm bone (HP:0003953)2.10153771
58Bladder carcinoma (HP:0002862)2.06133768
59Bladder neoplasm (HP:0009725)2.06133768
60Neoplasm of the small intestine (HP:0100833)2.03380979
61Biliary tract neoplasm (HP:0100574)2.02933711
62Abnormality of the hip-girdle musculature (HP:0001445)2.02425934
63Abnormality of the musculature of the pelvis (HP:0001469)2.02425934
64Insomnia (HP:0100785)2.00732265
65Abnormality of the anterior horn cell (HP:0006802)2.00597940
66Degeneration of anterior horn cells (HP:0002398)2.00597940
67Lower limb amyotrophy (HP:0007210)2.00343007
68Absent eyebrow (HP:0002223)2.00168122
69Carpal bone hypoplasia (HP:0001498)1.99921143
70Uterine neoplasm (HP:0010784)1.98671831
71Epileptic encephalopathy (HP:0200134)1.98096963
72Impaired smooth pursuit (HP:0007772)1.97876992
73Dialeptic seizures (HP:0011146)1.96486473
74Hammertoe (HP:0001765)1.96300204
75Ankyloglossia (HP:0010296)1.95740687
76Abnormal hair whorl (HP:0010721)1.93851683
77Genetic anticipation (HP:0003743)1.93820187
78CNS hypomyelination (HP:0003429)1.93568435
79Generalized hypotonia (HP:0001290)1.92516297
80Hyperinsulinemic hypoglycemia (HP:0000825)1.91796052
81Choanal stenosis (HP:0000452)1.91474737
82Aplasia/Hypoplasia of the sternum (HP:0006714)1.91228029
83Breast aplasia (HP:0100783)1.89144453
84Neoplasm of striated muscle (HP:0009728)1.87533373
85Generalized tonic-clonic seizures (HP:0002069)1.87264762
86Broad-based gait (HP:0002136)1.86835744
87Abdominal situs inversus (HP:0003363)1.86067288
88Abnormality of abdominal situs (HP:0011620)1.86067288
89Ankle clonus (HP:0011448)1.85664676
90Drooling (HP:0002307)1.85282514
91Excessive salivation (HP:0003781)1.85282514
92Progressive external ophthalmoplegia (HP:0000590)1.85036501
93Febrile seizures (HP:0002373)1.82399514
94Omphalocele (HP:0001539)1.80262534
95Inappropriate behavior (HP:0000719)1.80149796
96Rimmed vacuoles (HP:0003805)1.79451260
97Abnormality of ocular smooth pursuit (HP:0000617)1.79237796
98Asymmetry of the thorax (HP:0001555)1.78956290
99Overlapping toe (HP:0001845)1.78561637
100Papilledema (HP:0001085)1.78378137
101Back pain (HP:0003418)1.78255680
102Postnatal microcephaly (HP:0005484)1.77801009
103Mutism (HP:0002300)1.77506651
104Cystic hygroma (HP:0000476)1.77314886
105Oligodactyly (hands) (HP:0001180)1.77032451
106Abnormality of the corticospinal tract (HP:0002492)1.74779352
107Pointed chin (HP:0000307)1.74237630
108High anterior hairline (HP:0009890)1.72056584
109Spastic gait (HP:0002064)1.71255212
110Selective tooth agenesis (HP:0001592)1.71200010
111Aplasia/Hypoplasia of the breasts (HP:0010311)1.70776386
112Embryonal neoplasm (HP:0002898)1.70377640
113Impulsivity (HP:0100710)1.69994310
114Oligodactyly (HP:0012165)1.69884317
115Aplasia/hypoplasia of the humerus (HP:0006507)1.68901129
116Skull defect (HP:0001362)1.68563267
117Cortical dysplasia (HP:0002539)1.68291086
118Delusions (HP:0000746)1.67614409
119Abnormality of the salivary glands (HP:0010286)1.67377646
120Neoplasm of the thyroid gland (HP:0100031)1.67130036
121Abnormality of oral frenula (HP:0000190)1.65665622
122Increased nuchal translucency (HP:0010880)1.64631721
123Truncal ataxia (HP:0002078)1.64614145
124Arnold-Chiari malformation (HP:0002308)1.64552782
125Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.63469454
126Myelomeningocele (HP:0002475)1.63295234
127Deviation of the thumb (HP:0009603)1.63085416
128Symptomatic seizures (HP:0011145)1.63023432
129Peripheral hypomyelination (HP:0007182)1.62864945
130Spinal muscular atrophy (HP:0007269)1.62625134
131Gastroesophageal reflux (HP:0002020)1.62557013
132Unsteady gait (HP:0002317)1.62530042
133Broad palm (HP:0001169)1.62168083
134Hyperthyroidism (HP:0000836)1.61484174
135Nervous tissue neoplasm (HP:0030060)1.60140656
136Neuroectodermal neoplasm (HP:0030061)1.60140656
137Neuroepithelial neoplasm (HP:0030063)1.60140656
138Male infertility (HP:0003251)1.59891175
139Deep philtrum (HP:0002002)1.59138584
140Neoplasm of the colon (HP:0100273)1.58873883
141Limb-girdle muscle weakness (HP:0003325)1.58709068
142Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.58235152
143Short 1st metacarpal (HP:0010034)1.58235152
144Apathy (HP:0000741)1.57948810
145Malignant neoplasm of the central nervous system (HP:0100836)1.57862683
146Failure to thrive in infancy (HP:0001531)1.57753976
147Overriding aorta (HP:0002623)1.57527122
148Gaze-evoked nystagmus (HP:0000640)1.57520928
149Neoplasm of the rectum (HP:0100743)1.57412081
150Impaired pain sensation (HP:0007328)1.57203952
151Abnormality of pain sensation (HP:0010832)1.57203952
152Pheochromocytoma (HP:0002666)1.55177422
153Trigonocephaly (HP:0000243)1.55020606
154Truncus arteriosus (HP:0001660)1.54984104
155Short humerus (HP:0005792)1.54597877
156Attention deficit hyperactivity disorder (HP:0007018)1.54252824
157Gait imbalance (HP:0002141)1.53675868
158Malignant gastrointestinal tract tumors (HP:0006749)1.53363602
159Gastrointestinal carcinoma (HP:0002672)1.53363602
160Abnormality of the labia (HP:0000058)1.53118984
161Absent eyelashes (HP:0000561)1.52696497
162Horseshoe kidney (HP:0000085)1.52225204
163Primitive neuroectodermal tumor (HP:0030065)1.51985722
164Neuroblastic tumors (HP:0004376)1.51985722
165Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.51985722
166Prominent metopic ridge (HP:0005487)1.51284525
167Abnormal lung lobation (HP:0002101)1.51206428

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PNCK4.19009030
2MAP3K93.54362529
3WEE12.95508997
4MARK12.87472415
5CDC72.85984676
6TSSK62.80516407
7BUB12.66335335
8NTRK32.62341750
9MAP3K42.55327618
10LATS22.41620159
11NEK12.41372981
12MAP3K102.10574924
13AKT32.03172066
14PLK31.98066092
15TRIM281.97504164
16TTK1.86356987
17MINK11.85453041
18KSR21.79846392
19EEF2K1.76202286
20EPHA21.67133799
21KSR11.63797512
22EPHA41.57915810
23PLK41.50920959
24TNIK1.50615861
25PLK21.47955403
26SRPK11.46899389
27ERBB31.44279472
28MAP2K71.44240321
29SCYL21.40445302
30PLK11.37821312
31ALK1.33976372
32EIF2AK11.31960178
33TAF11.30863623
34PAK61.30790688
35PDGFRA1.30254142
36NEK21.29714330
37ARAF1.27782718
38EIF2AK31.24992234
39CDK61.21651946
40MST41.21104867
41BRAF1.21006298
42STK241.18819532
43RPS6KA41.18310150
44FGFR11.17615699
45MAP2K41.12422504
46MAP3K121.11602211
47NTRK21.11456717
48CHEK21.11449484
49CAMK1G1.04484108
50UHMK11.04041735
51SIK31.03499537
52CDK121.01727939
53STK31.01179877
54BRSK11.00110149
55PDK30.99406523
56PDK40.99406523
57FGFR40.94235440
58CHEK10.93098754
59AURKA0.90519835
60YES10.89611462
61CSNK1G20.89469146
62BRSK20.87259779
63MAPK130.86807854
64CSNK1E0.86013786
65DAPK10.84836054
66DYRK30.84298839
67CDK190.82499415
68RAF10.81923778
69BCR0.81729226
70CDK140.80317506
71ICK0.80142685
72SMG10.79622510
73PRKCG0.76439430
74ATR0.75753928
75CDK180.75601670
76ACVR1B0.75109059
77WNK30.75037658
78CDK20.74879062
79DYRK20.74798913
80STK160.74681706
81STK380.74586695
82MKNK10.74544869
83CDK150.74435573
84MELK0.73683039
85PBK0.73278706
86CSNK1G30.72430132
87TESK20.71156046
88BRD40.70637666
89MAP3K60.69578445
90MKNK20.69439336
91TYRO30.69325052
92CAMK1D0.68689001
93STK38L0.67602604
94PRKD30.67151978
95PAK40.66557663
96NTRK10.66164626
97ATM0.66082188
98CDK10.65633090
99RPS6KB20.64935785
100CDK11A0.64326533
101PASK0.62838586
102AURKB0.62161322
103LATS10.62043470
104CDK50.61950649
105PRKCI0.61891024
106FGFR20.59686772
107LIMK10.59548822
108CCNB10.58781281
109DMPK0.58695437
110CSNK1G10.58561939
111MAPK100.56953490
112ERBB40.56283907
113BMPR20.52140218
114MAP3K20.51760686
115MAP3K80.51239223
116PKN20.49506156
117SGK4940.49089281
118SGK2230.49089281
119PDK20.48400632
120DYRK1A0.48215772
121FGFR30.46953181
122CSNK1D0.46710830
123EIF2AK20.45592389
124CASK0.44925167
125CSNK1A1L0.44136791
126GRK50.43256214
127GSK3B0.43094339
128PRKDC0.42964310
129RET0.42799849
130SGK20.42477298
131CDK70.41840348
132CSNK2A20.41553593
133FLT30.40712544
134CDK40.40066625
135SGK30.39465538
136STK110.39404924
137DAPK20.39260888

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.86686406
2Nicotine addiction_Homo sapiens_hsa050332.69573483
3RNA transport_Homo sapiens_hsa030132.66083784
4Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.47665754
5Oocyte meiosis_Homo sapiens_hsa041142.47108976
6Synaptic vesicle cycle_Homo sapiens_hsa047212.41407833
7Mismatch repair_Homo sapiens_hsa034302.32390405
8Cell cycle_Homo sapiens_hsa041102.14964789
9Adherens junction_Homo sapiens_hsa045202.04715333
10Spliceosome_Homo sapiens_hsa030402.01891665
11RNA polymerase_Homo sapiens_hsa030201.99126367
12Long-term potentiation_Homo sapiens_hsa047201.98187069
13Proteasome_Homo sapiens_hsa030501.97021080
14Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.94170993
15DNA replication_Homo sapiens_hsa030301.87565966
16mRNA surveillance pathway_Homo sapiens_hsa030151.85334971
17Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.84330078
18Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.77614826
19Steroid biosynthesis_Homo sapiens_hsa001001.69969525
20Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.69384124
21Amphetamine addiction_Homo sapiens_hsa050311.68966280
22Dopaminergic synapse_Homo sapiens_hsa047281.61484275
23Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.60487461
242-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.59537678
25Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.59151645
26GABAergic synapse_Homo sapiens_hsa047271.58585048
27Biosynthesis of amino acids_Homo sapiens_hsa012301.56664836
28Nucleotide excision repair_Homo sapiens_hsa034201.51813501
29Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.48431705
30Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.40594932
31Selenocompound metabolism_Homo sapiens_hsa004501.39589407
32Olfactory transduction_Homo sapiens_hsa047401.38761245
33Basal transcription factors_Homo sapiens_hsa030221.37993934
34Central carbon metabolism in cancer_Homo sapiens_hsa052301.34091232
35RNA degradation_Homo sapiens_hsa030181.33405935
36Circadian entrainment_Homo sapiens_hsa047131.32860053
37Glutamatergic synapse_Homo sapiens_hsa047241.30275544
38Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.28100253
39Morphine addiction_Homo sapiens_hsa050321.27488911
40Long-term depression_Homo sapiens_hsa047301.21717850
41Fanconi anemia pathway_Homo sapiens_hsa034601.14636700
42Homologous recombination_Homo sapiens_hsa034401.14136891
43Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.14052980
44mTOR signaling pathway_Homo sapiens_hsa041501.11402132
45Collecting duct acid secretion_Homo sapiens_hsa049661.09758065
46Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.06022436
47Gap junction_Homo sapiens_hsa045401.05667120
48Colorectal cancer_Homo sapiens_hsa052101.05638696
49Carbon metabolism_Homo sapiens_hsa012001.05414490
50Insulin secretion_Homo sapiens_hsa049111.05353117
51Hippo signaling pathway_Homo sapiens_hsa043901.04942475
52Estrogen signaling pathway_Homo sapiens_hsa049151.04469335
53Taste transduction_Homo sapiens_hsa047421.03603798
54Cholinergic synapse_Homo sapiens_hsa047251.00367333
55GnRH signaling pathway_Homo sapiens_hsa049120.97502660
56Serotonergic synapse_Homo sapiens_hsa047260.96536794
57Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.95687049
58Oxytocin signaling pathway_Homo sapiens_hsa049210.95535694
59Protein export_Homo sapiens_hsa030600.95045672
60Non-homologous end-joining_Homo sapiens_hsa034500.94958057
61Salivary secretion_Homo sapiens_hsa049700.94498191
62Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.93215070
63Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.92858574
64Cocaine addiction_Homo sapiens_hsa050300.92515263
65Pyrimidine metabolism_Homo sapiens_hsa002400.91355275
66Base excision repair_Homo sapiens_hsa034100.89778473
67Vitamin B6 metabolism_Homo sapiens_hsa007500.87031444
68Chronic myeloid leukemia_Homo sapiens_hsa052200.86342698
69Alcoholism_Homo sapiens_hsa050340.84009670
70Vibrio cholerae infection_Homo sapiens_hsa051100.83763252
71Prostate cancer_Homo sapiens_hsa052150.83234306
72Epstein-Barr virus infection_Homo sapiens_hsa051690.82845235
73Gastric acid secretion_Homo sapiens_hsa049710.82480100
74Insulin signaling pathway_Homo sapiens_hsa049100.81555456
75Hedgehog signaling pathway_Homo sapiens_hsa043400.81235091
76Aldosterone synthesis and secretion_Homo sapiens_hsa049250.81129919
77Glioma_Homo sapiens_hsa052140.80173671
78Proteoglycans in cancer_Homo sapiens_hsa052050.79292334
79Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.79220251
80Wnt signaling pathway_Homo sapiens_hsa043100.79164583
81Melanogenesis_Homo sapiens_hsa049160.78236974
82p53 signaling pathway_Homo sapiens_hsa041150.77153003
83Phosphatidylinositol signaling system_Homo sapiens_hsa040700.76931946
84Dorso-ventral axis formation_Homo sapiens_hsa043200.75754124
85Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.75130559
86Tight junction_Homo sapiens_hsa045300.74973058
87ErbB signaling pathway_Homo sapiens_hsa040120.74770795
88Endometrial cancer_Homo sapiens_hsa052130.74381240
89Renin secretion_Homo sapiens_hsa049240.73866193
90Lysine degradation_Homo sapiens_hsa003100.73711515
91Purine metabolism_Homo sapiens_hsa002300.73211853
92Thyroid hormone signaling pathway_Homo sapiens_hsa049190.72907759
93One carbon pool by folate_Homo sapiens_hsa006700.72030022
94Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.70748253
95Pyruvate metabolism_Homo sapiens_hsa006200.70148960
96Thyroid cancer_Homo sapiens_hsa052160.70116221
97Calcium signaling pathway_Homo sapiens_hsa040200.69628189
98Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.68693267
99Axon guidance_Homo sapiens_hsa043600.67970770
100Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.66773921
101AMPK signaling pathway_Homo sapiens_hsa041520.66528170
102Renal cell carcinoma_Homo sapiens_hsa052110.65964651
103Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.65519080
104Type II diabetes mellitus_Homo sapiens_hsa049300.62187879
105Thyroid hormone synthesis_Homo sapiens_hsa049180.62005793
106Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.58938117
107Regulation of autophagy_Homo sapiens_hsa041400.57116153
108Pancreatic cancer_Homo sapiens_hsa052120.57002222
109Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.56909919
110Regulation of actin cytoskeleton_Homo sapiens_hsa048100.55193275
111MicroRNAs in cancer_Homo sapiens_hsa052060.55092139
112TGF-beta signaling pathway_Homo sapiens_hsa043500.54158048
113Type I diabetes mellitus_Homo sapiens_hsa049400.53712042
114Focal adhesion_Homo sapiens_hsa045100.52226139
115cAMP signaling pathway_Homo sapiens_hsa040240.51584708
116Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.51529353
117Fatty acid biosynthesis_Homo sapiens_hsa000610.51228266
118Inositol phosphate metabolism_Homo sapiens_hsa005620.50877607
119Choline metabolism in cancer_Homo sapiens_hsa052310.50365626
120MAPK signaling pathway_Homo sapiens_hsa040100.49206899
121Phototransduction_Homo sapiens_hsa047440.49196811
122Shigellosis_Homo sapiens_hsa051310.49065375
123Arginine and proline metabolism_Homo sapiens_hsa003300.48139503
124Cysteine and methionine metabolism_Homo sapiens_hsa002700.47955744
125Glucagon signaling pathway_Homo sapiens_hsa049220.47931000
126Viral carcinogenesis_Homo sapiens_hsa052030.46191277
127cGMP-PKG signaling pathway_Homo sapiens_hsa040220.45804719
128Neurotrophin signaling pathway_Homo sapiens_hsa047220.45691014
129Pentose phosphate pathway_Homo sapiens_hsa000300.45394423
130Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.44643159
131Bladder cancer_Homo sapiens_hsa052190.44395060
132Propanoate metabolism_Homo sapiens_hsa006400.43954813
133Basal cell carcinoma_Homo sapiens_hsa052170.43251785
134Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.42939352
135Circadian rhythm_Homo sapiens_hsa047100.42099614
136Longevity regulating pathway - mammal_Homo sapiens_hsa042110.40547676
137Non-small cell lung cancer_Homo sapiens_hsa052230.40342419

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »