GABRA3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)6.51726005
2synaptic vesicle maturation (GO:0016188)6.21926517
3glutamate secretion (GO:0014047)5.88767605
4synaptic vesicle docking involved in exocytosis (GO:0016081)5.88337809
5synaptic vesicle exocytosis (GO:0016079)5.88165959
6pyrimidine nucleobase catabolic process (GO:0006208)5.79114909
7positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.74276711
8locomotory exploration behavior (GO:0035641)5.73082435
9regulation of synaptic vesicle exocytosis (GO:2000300)5.61220446
10vocalization behavior (GO:0071625)5.58598155
11regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.45331297
12positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.42157347
13regulation of glutamate receptor signaling pathway (GO:1900449)5.08857574
14regulation of synaptic vesicle transport (GO:1902803)5.02259481
15protein localization to synapse (GO:0035418)4.94983131
16neuron cell-cell adhesion (GO:0007158)4.88591408
17nucleobase catabolic process (GO:0046113)4.81512274
18neurotransmitter secretion (GO:0007269)4.77112343
19neuronal action potential propagation (GO:0019227)4.73500551
20ionotropic glutamate receptor signaling pathway (GO:0035235)4.65660780
21exploration behavior (GO:0035640)4.48078711
22neurotransmitter-gated ion channel clustering (GO:0072578)4.45998491
23regulation of neuronal synaptic plasticity (GO:0048168)4.44260169
24regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.43373532
25regulation of long-term neuronal synaptic plasticity (GO:0048169)4.42275150
26proline transport (GO:0015824)4.38884982
27layer formation in cerebral cortex (GO:0021819)4.32868453
28synaptic transmission, glutamatergic (GO:0035249)4.23366593
29gamma-aminobutyric acid transport (GO:0015812)4.19666859
30protein polyglutamylation (GO:0018095)4.08044757
31neuron-neuron synaptic transmission (GO:0007270)4.03471872
32glutamate receptor signaling pathway (GO:0007215)4.02757548
33dendritic spine morphogenesis (GO:0060997)3.97552641
34membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.92253263
35neurotransmitter transport (GO:0006836)3.89582482
36establishment of mitochondrion localization (GO:0051654)3.88818871
37regulation of synapse structural plasticity (GO:0051823)3.83714875
38behavioral response to nicotine (GO:0035095)3.82666716
39positive regulation of membrane potential (GO:0045838)3.82233495
40long-term memory (GO:0007616)3.78378432
41regulation of excitatory postsynaptic membrane potential (GO:0060079)3.70191437
42long-term synaptic potentiation (GO:0060291)3.65498544
43cellular potassium ion homeostasis (GO:0030007)3.65070509
44regulation of neurotransmitter secretion (GO:0046928)3.63465391
45regulation of synaptic plasticity (GO:0048167)3.62426774
46neuron recognition (GO:0008038)3.59650235
47negative regulation of synaptic transmission, GABAergic (GO:0032229)3.59518079
48postsynaptic membrane organization (GO:0001941)3.59258582
49activation of protein kinase A activity (GO:0034199)3.58905729
50regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.55986186
51regulation of postsynaptic membrane potential (GO:0060078)3.55066812
52regulation of neurotransmitter levels (GO:0001505)3.54321111
53glycine transport (GO:0015816)3.54154000
54synaptic vesicle endocytosis (GO:0048488)3.51477081
55neuromuscular process controlling posture (GO:0050884)3.42796341
56regulation of synaptic transmission, glutamatergic (GO:0051966)3.42712238
57L-amino acid import (GO:0043092)3.42068584
58positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.41066127
59presynaptic membrane assembly (GO:0097105)3.39552790
60positive regulation of synaptic transmission, GABAergic (GO:0032230)3.38451075
61positive regulation of neurotransmitter secretion (GO:0001956)3.36922991
62positive regulation of neurotransmitter transport (GO:0051590)3.36859226
63regulation of dendritic spine morphogenesis (GO:0061001)3.34733807
64regulation of neurotransmitter transport (GO:0051588)3.34614124
65cerebellar Purkinje cell differentiation (GO:0021702)3.32737899
66sodium ion export (GO:0071436)3.29890845
67regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.28526121
68axonal fasciculation (GO:0007413)3.27861047
69glycosphingolipid biosynthetic process (GO:0006688)3.27381813
70transmission of nerve impulse (GO:0019226)3.25966183
71* gamma-aminobutyric acid signaling pathway (GO:0007214)3.25680863
72neuromuscular process controlling balance (GO:0050885)3.24642246
73positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.23204871
74positive regulation of synapse maturation (GO:0090129)3.21937677
75positive regulation of synaptic transmission (GO:0050806)3.21194858
76regulation of vesicle fusion (GO:0031338)3.20647246
77presynaptic membrane organization (GO:0097090)3.18738862
78vesicle transport along microtubule (GO:0047496)3.17882304
79regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.15927651
80response to auditory stimulus (GO:0010996)3.15774466
81auditory behavior (GO:0031223)3.12367990
82membrane hyperpolarization (GO:0060081)3.10656055
83regulation of synaptic transmission (GO:0050804)3.10200689
84membrane depolarization (GO:0051899)3.08222739
85neuronal ion channel clustering (GO:0045161)3.08103774
86positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.07134044
87G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.05856741
88negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.04176509
89* synaptic transmission (GO:0007268)3.02688073
90membrane depolarization during action potential (GO:0086010)3.02676814
91neuromuscular synaptic transmission (GO:0007274)3.02207928
92cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.01874602
93learning (GO:0007612)3.01826900
94dendrite morphogenesis (GO:0048813)3.00408268
95cell migration in hindbrain (GO:0021535)3.00372490
96social behavior (GO:0035176)2.99248920
97intraspecies interaction between organisms (GO:0051703)2.99248920
98response to histamine (GO:0034776)2.98845907
99startle response (GO:0001964)2.98568006
100neuronal action potential (GO:0019228)2.96194627
101neurofilament cytoskeleton organization (GO:0060052)2.95628814
102neuromuscular process (GO:0050905)2.95250142
103innervation (GO:0060384)2.93782325
104positive regulation of mitochondrial fission (GO:0090141)2.93370709
105G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.93274987
106cell communication by electrical coupling (GO:0010644)2.92209106
107regulation of synaptic transmission, GABAergic (GO:0032228)2.91826736
108regulation of dendritic spine development (GO:0060998)2.91499649
109synapse assembly (GO:0007416)2.89977607
110prepulse inhibition (GO:0060134)2.86971694
111protein localization to cilium (GO:0061512)2.86570989
112calcium ion-dependent exocytosis (GO:0017156)2.82333733
113mitochondrion transport along microtubule (GO:0047497)2.82176944
114establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.82176944
115regulation of feeding behavior (GO:0060259)2.81617261
116retinal cone cell development (GO:0046549)2.81323401
117response to pheromone (GO:0019236)2.79409335
118regulation of cilium movement (GO:0003352)2.75288063
119positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.73769693
120positive regulation of oligodendrocyte differentiation (GO:0048714)2.73288521
121regulation of microtubule-based movement (GO:0060632)2.69206707
122mechanosensory behavior (GO:0007638)2.66838029
123synapse organization (GO:0050808)2.66448436
124regulation of voltage-gated calcium channel activity (GO:1901385)2.65050525
125protein-cofactor linkage (GO:0018065)2.64805163
126positive regulation of synapse assembly (GO:0051965)2.62901747
127sleep (GO:0030431)2.59579263
128negative regulation of telomere maintenance (GO:0032205)2.58876135
129adult behavior (GO:0030534)2.57108031
130behavioral fear response (GO:0001662)2.56230955
131behavioral defense response (GO:0002209)2.56230955
132response to dietary excess (GO:0002021)2.55979242
133response to gravity (GO:0009629)2.55153191
134negative regulation of heart rate (GO:0010459)2.54746239
135adult walking behavior (GO:0007628)2.53188494
136positive regulation of amino acid transport (GO:0051957)2.52627973
137central nervous system projection neuron axonogenesis (GO:0021952)2.52438707

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.90694162
2GBX2_23144817_ChIP-Seq_PC3_Human3.78302625
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.11329161
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.98761543
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.98651922
6RNF2_18974828_ChIP-Seq_MESCs_Mouse2.69969749
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.69969749
8REST_21632747_ChIP-Seq_MESCs_Mouse2.68297729
9SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.57932047
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.55628275
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.50808232
12SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.47164561
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.46453884
14EZH2_27304074_Chip-Seq_ESCs_Mouse2.46207419
15DROSHA_22980978_ChIP-Seq_HELA_Human2.44126365
16RARB_27405468_Chip-Seq_BRAIN_Mouse2.43100628
17SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.42808129
18EED_16625203_ChIP-ChIP_MESCs_Mouse2.27220725
19NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.22788562
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.20176424
21REST_18959480_ChIP-ChIP_MESCs_Mouse2.19907521
22EZH2_27294783_Chip-Seq_ESCs_Mouse2.15360235
23RNF2_27304074_Chip-Seq_ESCs_Mouse2.13241827
24GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.07461953
25AR_21572438_ChIP-Seq_LNCaP_Human2.07108587
26CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.98021088
27VDR_22108803_ChIP-Seq_LS180_Human1.94992929
28IKZF1_21737484_ChIP-ChIP_HCT116_Human1.93756024
29ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.91189219
30CTBP2_25329375_ChIP-Seq_LNCAP_Human1.84919917
31FLI1_27457419_Chip-Seq_LIVER_Mouse1.84740240
32TAF15_26573619_Chip-Seq_HEK293_Human1.84192244
33MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.76756851
34EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.70902654
35* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.68791096
36* SMAD4_21799915_ChIP-Seq_A2780_Human1.67875558
37CTBP1_25329375_ChIP-Seq_LNCAP_Human1.63663321
38SMAD_19615063_ChIP-ChIP_OVARY_Human1.57526390
39ZFP57_27257070_Chip-Seq_ESCs_Mouse1.51956523
40PCGF2_27294783_Chip-Seq_ESCs_Mouse1.49935532
41ERG_21242973_ChIP-ChIP_JURKAT_Human1.47072923
42IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.45177712
43CBP_20019798_ChIP-Seq_JUKART_Human1.45177712
44PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.42725761
45GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.40078396
46P300_19829295_ChIP-Seq_ESCs_Human1.39568545
47EWS_26573619_Chip-Seq_HEK293_Human1.38908443
48SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.35744332
49SOX2_21211035_ChIP-Seq_LN229_Gbm1.34245305
50CBX2_27304074_Chip-Seq_ESCs_Mouse1.30433241
51FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.30156400
52RING1B_27294783_Chip-Seq_ESCs_Mouse1.28664407
53IRF1_19129219_ChIP-ChIP_H3396_Human1.28547819
54MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.28133257
55AR_25329375_ChIP-Seq_VCAP_Human1.28131595
56RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.28075430
57PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.27902060
58SMAD3_21741376_ChIP-Seq_EPCs_Human1.27793675
59MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.27418102
60TP53_22573176_ChIP-Seq_HFKS_Human1.26936209
61RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.24891556
62STAT3_23295773_ChIP-Seq_U87_Human1.24315881
63NR3C1_23031785_ChIP-Seq_PC12_Mouse1.22668904
64CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.21213243
65HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.21158403
66PIAS1_25552417_ChIP-Seq_VCAP_Human1.20717331
67MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.20129441
68TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.19019086
69* AR_19668381_ChIP-Seq_PC3_Human1.18421774
70OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.18388996
71ZNF274_21170338_ChIP-Seq_K562_Hela1.17007620
72RNF2_27304074_Chip-Seq_NSC_Mouse1.16617873
73BMI1_23680149_ChIP-Seq_NPCS_Mouse1.16211679
74TOP2B_26459242_ChIP-Seq_MCF-7_Human1.16154438
75SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.15972219
76DNAJC2_21179169_ChIP-ChIP_NT2_Human1.14728141
77NANOG_18555785_Chip-Seq_ESCs_Mouse1.14474153
78SUZ12_27294783_Chip-Seq_NPCs_Mouse1.13105433
79KLF5_20875108_ChIP-Seq_MESCs_Mouse1.12882802
80TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.11806872
81TCF4_23295773_ChIP-Seq_U87_Human1.11310388
82P53_22127205_ChIP-Seq_FIBROBLAST_Human1.10856375
83WT1_25993318_ChIP-Seq_PODOCYTE_Human1.10700283
84SALL1_21062744_ChIP-ChIP_HESCs_Human1.10187195
85CDX2_19796622_ChIP-Seq_MESCs_Mouse1.09720041
86GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.07770777
87ZNF217_24962896_ChIP-Seq_MCF-7_Human1.07457752
88POU3F2_20337985_ChIP-ChIP_501MEL_Human1.07050826
89MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.06349887
90AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.04677765
91PCGF2_27294783_Chip-Seq_NPCs_Mouse1.04536976
92YAP1_20516196_ChIP-Seq_MESCs_Mouse1.04462993
93ARNT_22903824_ChIP-Seq_MCF-7_Human1.04417307
94ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.04264971
95RING1B_27294783_Chip-Seq_NPCs_Mouse1.03006546
96TAL1_26923725_Chip-Seq_HPCs_Mouse1.02905938
97ETV2_25802403_ChIP-Seq_MESCs_Mouse1.02471611
98* TCF4_22108803_ChIP-Seq_LS180_Human0.99644496
99P53_22387025_ChIP-Seq_ESCs_Mouse0.99615419
100NFE2_27457419_Chip-Seq_LIVER_Mouse0.98596873
101BCAT_22108803_ChIP-Seq_LS180_Human0.97584866
102RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.97548475
103AHR_22903824_ChIP-Seq_MCF-7_Human0.97399114
104FLI1_21867929_ChIP-Seq_TH2_Mouse0.97379505
105EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.97376931
106CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96555207
107PRDM14_20953172_ChIP-Seq_ESCs_Human0.96535906
108KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.96313046
109IGF1R_20145208_ChIP-Seq_DFB_Human0.94694344
110TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.94297900
111RUNX2_22187159_ChIP-Seq_PCA_Human0.94259544
112FUS_26573619_Chip-Seq_HEK293_Human0.94259323
113NR3C1_21868756_ChIP-Seq_MCF10A_Human0.94096965
114UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.93346221
115SMAD4_21741376_ChIP-Seq_HESCs_Human0.92655187
116WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.91927523
117EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.91674237
118SMAD3_21741376_ChIP-Seq_ESCs_Human0.91608975
119KDM2B_26808549_Chip-Seq_K562_Human0.91209024
120TP53_16413492_ChIP-PET_HCT116_Human0.90741087
121SMAD3_21741376_ChIP-Seq_HESCs_Human0.90527952
122TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90462367
123* ZFP281_18757296_ChIP-ChIP_E14_Mouse0.90323476
124ER_23166858_ChIP-Seq_MCF-7_Human0.90303683
125RXR_22108803_ChIP-Seq_LS180_Human0.89463133
126TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.88210449
127JUN_21703547_ChIP-Seq_K562_Human0.87070690
128POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.86494106
129TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86494106

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.59617863
2MP0003880_abnormal_central_pattern5.20759490
3* MP0003635_abnormal_synaptic_transmissio4.23151549
4MP0004270_analgesia3.81834566
5MP0009745_abnormal_behavioral_response3.48339302
6MP0002063_abnormal_learning/memory/cond3.39407031
7MP0002064_seizures3.35483224
8MP0009046_muscle_twitch3.30405747
9MP0001968_abnormal_touch/_nociception3.07088717
10MP0005423_abnormal_somatic_nervous2.93189031
11MP0002572_abnormal_emotion/affect_behav2.86868823
12MP0002734_abnormal_mechanical_nocicepti2.74954614
13MP0002102_abnormal_ear_morphology2.69632974
14* MP0001486_abnormal_startle_reflex2.62579204
15MP0002272_abnormal_nervous_system2.62427908
16MP0008877_abnormal_DNA_methylation2.52546320
17MP0001501_abnormal_sleep_pattern2.42690873
18MP0002736_abnormal_nociception_after2.35642416
19MP0002822_catalepsy2.35214925
20MP0009780_abnormal_chondrocyte_physiolo2.31763553
21MP0001440_abnormal_grooming_behavior2.05390771
22MP0002733_abnormal_thermal_nociception2.03567044
23MP0001970_abnormal_pain_threshold2.02158219
24MP0002067_abnormal_sensory_capabilities1.99732047
25MP0005646_abnormal_pituitary_gland1.96653363
26MP0002735_abnormal_chemical_nociception1.90727233
27MP0008569_lethality_at_weaning1.88935711
28MP0003787_abnormal_imprinting1.85079996
29MP0002557_abnormal_social/conspecific_i1.76223460
30MP0004811_abnormal_neuron_physiology1.73854961
31MP0003329_amyloid_beta_deposits1.72576030
32MP0000778_abnormal_nervous_system1.72268769
33MP0004924_abnormal_behavior1.70844076
34MP0005386_behavior/neurological_phenoty1.70844076
35MP0003879_abnormal_hair_cell1.68347820
36MP0002184_abnormal_innervation1.66124511
37MP0006276_abnormal_autonomic_nervous1.62153527
38MP0004858_abnormal_nervous_system1.61262027
39MP0001986_abnormal_taste_sensitivity1.55209838
40MP0000955_abnormal_spinal_cord1.52921170
41MP0002909_abnormal_adrenal_gland1.52654389
42MP0001984_abnormal_olfaction1.52438011
43MP0003122_maternal_imprinting1.52150452
44MP0004885_abnormal_endolymph1.48242944
45MP0005645_abnormal_hypothalamus_physiol1.48159337
46* MP0002066_abnormal_motor_capabilities/c1.43388814
47MP0006072_abnormal_retinal_apoptosis1.39598144
48MP0002882_abnormal_neuron_morphology1.39494880
49MP0003633_abnormal_nervous_system1.37319263
50MP0004142_abnormal_muscle_tone1.32145053
51MP0001502_abnormal_circadian_rhythm1.28778081
52MP0008789_abnormal_olfactory_epithelium1.23805504
53MP0005253_abnormal_eye_physiology1.22755599
54MP0001905_abnormal_dopamine_level1.21011523
55MP0002653_abnormal_ependyma_morphology1.18960416
56MP0003631_nervous_system_phenotype1.15197071
57MP0001529_abnormal_vocalization1.13481318
58MP0004147_increased_porphyrin_level1.10966035
59MP0000751_myopathy1.10825826
60MP0002152_abnormal_brain_morphology1.07510602
61MP0008872_abnormal_physiological_respon1.06657926
62MP0002751_abnormal_autonomic_nervous0.99456043
63MP0001177_atelectasis0.98375593
64MP0003690_abnormal_glial_cell0.98247270
65MP0010386_abnormal_urinary_bladder0.98208264
66MP0006292_abnormal_olfactory_placode0.97194422
67MP0005394_taste/olfaction_phenotype0.95476529
68MP0005499_abnormal_olfactory_system0.95476529
69MP0002069_abnormal_eating/drinking_beha0.95127897
70MP0000569_abnormal_digit_pigmentation0.94177239
71MP0002229_neurodegeneration0.93763747
72MP0002234_abnormal_pharynx_morphology0.91621919
73MP0008874_decreased_physiological_sensi0.90965825
74MP0005551_abnormal_eye_electrophysiolog0.89856519
75MP0000013_abnormal_adipose_tissue0.89045347
76MP0004742_abnormal_vestibular_system0.87590994
77MP0001963_abnormal_hearing_physiology0.85714050
78MP0002837_dystrophic_cardiac_calcinosis0.81853114
79MP0000026_abnormal_inner_ear0.81584716
80MP0005535_abnormal_body_temperature0.81102110
81MP0004133_heterotaxia0.80991134
82MP0008995_early_reproductive_senescence0.80466066
83MP0003634_abnormal_glial_cell0.80314165
84MP0004085_abnormal_heartbeat0.80035958
85MP0001188_hyperpigmentation0.79676852
86MP0003075_altered_response_to0.79480786
87MP0004145_abnormal_muscle_electrophysio0.78937556
88MP0000920_abnormal_myelination0.77642954
89MP0002876_abnormal_thyroid_physiology0.77564618
90MP0003632_abnormal_nervous_system0.77310147
91MP0003011_delayed_dark_adaptation0.76119971
92MP0008961_abnormal_basal_metabolism0.75722732
93MP0003119_abnormal_digestive_system0.75324477
94MP0005084_abnormal_gallbladder_morpholo0.74554506
95MP0000631_abnormal_neuroendocrine_gland0.72183767
96MP0000604_amyloidosis0.71996881
97MP0005167_abnormal_blood-brain_barrier0.70725114
98MP0005195_abnormal_posterior_eye0.70698411
99MP0002752_abnormal_somatic_nervous0.69642927
100MP0004215_abnormal_myocardial_fiber0.67602708
101MP0000427_abnormal_hair_cycle0.66560780
102MP0001664_abnormal_digestion0.65820100
103MP0003938_abnormal_ear_development0.65748604
104MP0004484_altered_response_of0.65687097
105MP0003698_abnormal_male_reproductive0.65517787
106MP0003861_abnormal_nervous_system0.63927611
107MP0003283_abnormal_digestive_organ0.63094652
108MP0002638_abnormal_pupillary_reflex0.63006862
109MP0008875_abnormal_xenobiotic_pharmacok0.62253818
110MP0001485_abnormal_pinna_reflex0.62176714
111MP0004233_abnormal_muscle_weight0.59728679
112MP0000049_abnormal_middle_ear0.59093150
113MP0002090_abnormal_vision0.59056972
114MP0005623_abnormal_meninges_morphology0.58474988
115MP0003137_abnormal_impulse_conducting0.57150170
116MP0003646_muscle_fatigue0.56854948
117MP0001943_abnormal_respiration0.56622531
118MP0003121_genomic_imprinting0.55854984
119MP0010769_abnormal_survival0.53555588
120MP0004043_abnormal_pH_regulation0.52651170
121MP0010770_preweaning_lethality0.52597283
122MP0002082_postnatal_lethality0.52597283
123MP0001299_abnormal_eye_distance/0.52027784
124MP0003123_paternal_imprinting0.51805568

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.92633852
2Myokymia (HP:0002411)6.90099793
3Focal seizures (HP:0007359)5.82463044
4Epileptic encephalopathy (HP:0200134)5.09429991
5Visual hallucinations (HP:0002367)4.96749325
6Atonic seizures (HP:0010819)4.89573982
7Febrile seizures (HP:0002373)4.70845815
8Progressive cerebellar ataxia (HP:0002073)4.31585852
9Absence seizures (HP:0002121)4.14357956
10Generalized tonic-clonic seizures (HP:0002069)4.02428691
11Ankle clonus (HP:0011448)3.77144882
12Dialeptic seizures (HP:0011146)3.76320549
13Impaired vibration sensation in the lower limbs (HP:0002166)3.70049128
14Supranuclear gaze palsy (HP:0000605)3.61247849
15Action tremor (HP:0002345)3.54637439
16Broad-based gait (HP:0002136)3.52709105
17Abnormal eating behavior (HP:0100738)3.45642689
18Hyperventilation (HP:0002883)3.39443011
19Papilledema (HP:0001085)3.39031242
20Urinary bladder sphincter dysfunction (HP:0002839)3.38052658
21Poor eye contact (HP:0000817)3.35431228
22Depression (HP:0000716)3.34752625
23Mutism (HP:0002300)3.23635531
24Gaze-evoked nystagmus (HP:0000640)3.20174492
25Postural instability (HP:0002172)3.16626476
26Dysdiadochokinesis (HP:0002075)3.13718982
27Dysmetria (HP:0001310)3.03967234
28Impaired social interactions (HP:0000735)3.01786095
29Abnormal social behavior (HP:0012433)3.01786095
30Progressive inability to walk (HP:0002505)3.00048475
31Retinal dysplasia (HP:0007973)2.95703392
32Urinary urgency (HP:0000012)2.92710315
33Lissencephaly (HP:0001339)2.91783589
34Anxiety (HP:0000739)2.89578296
35Truncal ataxia (HP:0002078)2.86672841
36Amblyopia (HP:0000646)2.80124284
37Torticollis (HP:0000473)2.77899180
38Type II lissencephaly (HP:0007260)2.77660487
39Abnormality of the labia minora (HP:0012880)2.76782110
40Nephronophthisis (HP:0000090)2.75846270
41Polyphagia (HP:0002591)2.75352560
42Spastic gait (HP:0002064)2.74346932
43Medial flaring of the eyebrow (HP:0010747)2.70651969
44Excessive salivation (HP:0003781)2.69092118
45Drooling (HP:0002307)2.69092118
46Diplopia (HP:0000651)2.68456608
47Abnormality of binocular vision (HP:0011514)2.68456608
48Focal dystonia (HP:0004373)2.65654292
49Genetic anticipation (HP:0003743)2.62426283
50Fetal akinesia sequence (HP:0001989)2.62126444
51Bradykinesia (HP:0002067)2.60899260
52Abnormality of midbrain morphology (HP:0002418)2.55545703
53Molar tooth sign on MRI (HP:0002419)2.55545703
54Hypoplasia of the brainstem (HP:0002365)2.54565766
55Aplasia/Hypoplasia of the brainstem (HP:0007362)2.54565766
56Pachygyria (HP:0001302)2.53759514
57Impaired vibratory sensation (HP:0002495)2.53265651
58Hemiplegia (HP:0002301)2.49746069
59Impaired smooth pursuit (HP:0007772)2.49191504
60Hemiparesis (HP:0001269)2.49114530
61Pancreatic cysts (HP:0001737)2.47129155
62Abnormality of the lower motor neuron (HP:0002366)2.46779334
63Spastic tetraplegia (HP:0002510)2.45457202
64Nephrogenic diabetes insipidus (HP:0009806)2.40499555
65Inability to walk (HP:0002540)2.40497472
66Pheochromocytoma (HP:0002666)2.40428946
67Ventricular fibrillation (HP:0001663)2.39484277
68Epileptiform EEG discharges (HP:0011182)2.37298540
69Absent speech (HP:0001344)2.36619172
70Scanning speech (HP:0002168)2.36536339
71Limb dystonia (HP:0002451)2.36450919
72Lower limb muscle weakness (HP:0007340)2.36096990
73Neurofibrillary tangles (HP:0002185)2.36037844
74Poor suck (HP:0002033)2.35618322
75Stereotypic behavior (HP:0000733)2.33806557
76Termporal pattern (HP:0011008)2.33033505
77Insidious onset (HP:0003587)2.33033505
78Craniofacial dystonia (HP:0012179)2.32753980
79Status epilepticus (HP:0002133)2.32573862
80Abnormality of the corticospinal tract (HP:0002492)2.30212389
81Pancreatic fibrosis (HP:0100732)2.30178600
82Intention tremor (HP:0002080)2.29453140
83Dysmetric saccades (HP:0000641)2.29238343
84Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.26077061
85Degeneration of the lateral corticospinal tracts (HP:0002314)2.26077061
86EEG with generalized epileptiform discharges (HP:0011198)2.23214296
87True hermaphroditism (HP:0010459)2.23162400
88Morphological abnormality of the pyramidal tract (HP:0002062)2.20495801
89Genital tract atresia (HP:0001827)2.20347869
90Pendular nystagmus (HP:0012043)2.19530537
91Renal cortical cysts (HP:0000803)2.19228445
92Gait imbalance (HP:0002141)2.19216977
93Cerebral inclusion bodies (HP:0100314)2.19092992
94Generalized myoclonic seizures (HP:0002123)2.18731449
95Abnormality of ocular smooth pursuit (HP:0000617)2.17684853
96Vaginal atresia (HP:0000148)2.17142174
97Cerebral hypomyelination (HP:0006808)2.15634329
98Hypsarrhythmia (HP:0002521)2.13554420
99Dyskinesia (HP:0100660)2.12445149
100Specific learning disability (HP:0001328)2.11747805
101Congenital stationary night blindness (HP:0007642)2.10876415
102Optic nerve hypoplasia (HP:0000609)2.10800341
103Abnormality of the renal medulla (HP:0100957)2.10678187
104Blue irides (HP:0000635)2.08269585
105Neuronal loss in central nervous system (HP:0002529)2.05602020
106Failure to thrive in infancy (HP:0001531)2.05073223
107Neuroendocrine neoplasm (HP:0100634)2.04136055
108Megalencephaly (HP:0001355)2.01788132
109Split foot (HP:0001839)2.00716015
110Methylmalonic acidemia (HP:0002912)1.99272967
111Abolished electroretinogram (ERG) (HP:0000550)1.98560048
112Incomplete penetrance (HP:0003829)1.97353858
113Atrophy/Degeneration involving motor neurons (HP:0007373)1.96552992
114Gait ataxia (HP:0002066)1.96163852
115Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.95215104
116Clonus (HP:0002169)1.95029638
117Insomnia (HP:0100785)1.94271141
118Stomach cancer (HP:0012126)1.93397306
119Hypothermia (HP:0002045)1.93330174
120Delusions (HP:0000746)1.92897109
121Akinesia (HP:0002304)1.92486177
122Agitation (HP:0000713)1.92123359
123Pointed chin (HP:0000307)1.89731493
124Abnormality of the renal cortex (HP:0011035)1.89187468
125Abnormality of saccadic eye movements (HP:0000570)1.87546722
126Muscular hypotonia of the trunk (HP:0008936)1.86014639
127Sleep apnea (HP:0010535)1.85331045
128Abnormality of salivation (HP:0100755)1.84780404
129Protruding tongue (HP:0010808)1.83919049
130Annular pancreas (HP:0001734)1.83344953
131Rigidity (HP:0002063)1.83073853
132Peripheral hypomyelination (HP:0007182)1.83071491
133Neoplasm of the peripheral nervous system (HP:0100007)1.82323387
134CNS hypomyelination (HP:0003429)1.82061272
135Bundle branch block (HP:0011710)1.81198183
136Oligodactyly (hands) (HP:0001180)1.79638969
137Inappropriate behavior (HP:0000719)1.79576009
138Ulnar claw (HP:0001178)1.79544490
139Obstructive sleep apnea (HP:0002870)1.79024271
140Amyotrophic lateral sclerosis (HP:0007354)1.76551226
141Congenital primary aphakia (HP:0007707)1.75058910
142Attenuation of retinal blood vessels (HP:0007843)1.74785912
143Resting tremor (HP:0002322)1.72875200
144Hypoplasia of the corpus callosum (HP:0002079)1.70412095
145Synostosis involving the elbow (HP:0003938)1.69871838
146Humeroradial synostosis (HP:0003041)1.69871838
147Sclerocornea (HP:0000647)1.68852341
148Thyroid-stimulating hormone excess (HP:0002925)1.67933066

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.16984641
2MAP3K93.86358201
3EPHA43.74891594
4MAP3K43.52805380
5MAP4K23.42482762
6MARK13.14908745
7MAP2K73.07282466
8DAPK22.68314688
9PAK62.60660700
10BCR2.57589154
11MINK12.50049691
12CASK2.44670533
13MAP3K122.39774143
14MAP2K42.15264532
15CDK192.07192378
16NTRK22.03973727
17TRIM281.99222765
18KSR21.93706111
19PRKD31.89172433
20DYRK21.87022920
21TAOK31.85427676
22DAPK11.66119032
23EPHA31.65339386
24PLK21.64427535
25CAMKK11.64367432
26CSNK1G31.60497388
27FRK1.59457599
28TXK1.58223494
29CDK51.55589896
30NTRK11.54141163
31RIPK41.51604010
32KSR11.50609124
33CSNK1A1L1.47106535
34STK381.46614574
35TNIK1.43807271
36ERBB31.43802570
37MAPK131.43466397
38GRK51.37530840
39CSNK1G11.29855589
40PRPF4B1.28618135
41LATS21.23954699
42SIK21.19942506
43TAOK11.19801935
44OXSR11.18835685
45PRKCG1.18620733
46UHMK11.16519231
47ARAF1.11701743
48ZAK1.09179984
49SGK4941.05076429
50SGK2231.05076429
51MAP3K131.04892465
52MAP2K21.04599696
53FES1.03759593
54TYRO31.00299250
55ADRBK21.00174952
56MAP3K20.96594467
57CDK180.94386374
58TLK10.93958286
59SGK20.93866668
60PHKG20.93795860
61PHKG10.93795860
62CAMK2A0.93424043
63CDK150.92576165
64STK110.88994254
65PAK30.87794212
66GRK10.87133051
67CDK140.86852129
68GRK70.86483995
69CAMK10.85734126
70BCKDK0.84835142
71PRKCH0.84380052
72PINK10.84291073
73PNCK0.82028175
74CDK11A0.79903842
75INSRR0.79747965
76SGK30.79258073
77RET0.77723959
78LIMK10.77144089
79TNK20.76566428
80CCNB10.76433008
81RAF10.73331480
82ALK0.71927315
83CAMKK20.70523377
84GRK60.68559648
85PTK2B0.67989187
86SGK10.67344353
87WNK40.66033349
88DYRK1A0.65702557
89CAMK2B0.65414449
90LMTK20.64624790
91CSNK1G20.63414901
92MARK20.62872862
93PDK10.61265225
94AKT30.61243306
95BMPR20.60471948
96MAP3K60.58918545
97NEK60.57511505
98PDPK10.56470144
99NEK10.54350958
100CSNK1D0.51242807
101WNK30.50596010
102PRKCE0.49272443
103RPS6KA30.47628221
104NUAK10.47498544
105SIK30.47381118
106MAP3K10.47282784
107PRKCZ0.46125773
108PRKACA0.45164939
109CAMK2G0.44759212
110CDC42BPA0.43502210
111WNK10.42755834
112CSNK1A10.41107258
113BRSK10.40752808
114MAPK100.40412816
115BMPR1B0.40090766
116DAPK30.39957028
117BRAF0.39880127
118FYN0.39551067
119RPS6KA40.38916953
120PDK30.38023383
121PDK40.38023383
122FER0.35220282
123PRKG10.34984067
124MAP2K10.34867798
125CAMK1G0.34520986
126PRKCA0.34468840
127CAMK2D0.34357583
128MAP3K70.34255001
129ADRBK10.33759621
130CAMK40.33535593
131CDK30.32876768
132MUSK0.32157637
133CSNK1E0.31588532
134PRKAA10.31103121
135PKN10.30527739
136PRKACB0.30290448
137SCYL20.30242868
138MAPK90.29314306
139DYRK30.28629718
140TESK10.28625551
141RPS6KA50.27390495
142PRKCB0.25707265

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047213.75404273
2* Nicotine addiction_Homo sapiens_hsa050333.72505423
3Olfactory transduction_Homo sapiens_hsa047402.83220115
4* GABAergic synapse_Homo sapiens_hsa047272.73091526
5Circadian entrainment_Homo sapiens_hsa047132.64819900
6* Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.61989719
7Glutamatergic synapse_Homo sapiens_hsa047242.55715988
8Long-term potentiation_Homo sapiens_hsa047202.47015839
9* Morphine addiction_Homo sapiens_hsa050322.46619259
10Amphetamine addiction_Homo sapiens_hsa050312.38681596
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.13344055
12Salivary secretion_Homo sapiens_hsa049702.11638796
13Dopaminergic synapse_Homo sapiens_hsa047282.10003764
14Insulin secretion_Homo sapiens_hsa049112.02778184
15Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.99100525
16Gastric acid secretion_Homo sapiens_hsa049711.86673702
17Collecting duct acid secretion_Homo sapiens_hsa049661.84281351
18Cholinergic synapse_Homo sapiens_hsa047251.80296212
19Oxidative phosphorylation_Homo sapiens_hsa001901.76933031
20Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.76485235
21Aldosterone synthesis and secretion_Homo sapiens_hsa049251.71411196
22Cocaine addiction_Homo sapiens_hsa050301.61917162
23Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.60927892
24Renin secretion_Homo sapiens_hsa049241.60691897
25Oxytocin signaling pathway_Homo sapiens_hsa049211.60215192
26Serotonergic synapse_Homo sapiens_hsa047261.59888485
27Long-term depression_Homo sapiens_hsa047301.58800916
28Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.57828801
29* Taste transduction_Homo sapiens_hsa047421.51366431
30Calcium signaling pathway_Homo sapiens_hsa040201.50880968
31Parkinsons disease_Homo sapiens_hsa050121.43483123
32GnRH signaling pathway_Homo sapiens_hsa049121.38852062
33Butanoate metabolism_Homo sapiens_hsa006501.36433878
34Gap junction_Homo sapiens_hsa045401.28884212
35cAMP signaling pathway_Homo sapiens_hsa040241.26402560
36Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.26115289
37Nitrogen metabolism_Homo sapiens_hsa009101.25928180
38Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.25811179
39Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.23921523
40Protein export_Homo sapiens_hsa030601.21110041
41Type II diabetes mellitus_Homo sapiens_hsa049301.19613751
42Alzheimers disease_Homo sapiens_hsa050101.15206913
43Vibrio cholerae infection_Homo sapiens_hsa051101.13574799
44Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.13516398
45Regulation of autophagy_Homo sapiens_hsa041401.10907249
46Estrogen signaling pathway_Homo sapiens_hsa049151.10488343
47Axon guidance_Homo sapiens_hsa043601.09812932
48ErbB signaling pathway_Homo sapiens_hsa040121.08055900
49Glioma_Homo sapiens_hsa052141.06968866
50Phosphatidylinositol signaling system_Homo sapiens_hsa040701.04662657
51* Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.04540208
52Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.97651025
53Melanogenesis_Homo sapiens_hsa049160.96157300
54cGMP-PKG signaling pathway_Homo sapiens_hsa040220.95833034
55Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.92626576
56Ether lipid metabolism_Homo sapiens_hsa005650.91792652
57Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.90721947
58Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.90371194
59Linoleic acid metabolism_Homo sapiens_hsa005910.87237639
60Vascular smooth muscle contraction_Homo sapiens_hsa042700.86890761
61Dorso-ventral axis formation_Homo sapiens_hsa043200.83342428
62Cardiac muscle contraction_Homo sapiens_hsa042600.82603045
63Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.81672956
64Oocyte meiosis_Homo sapiens_hsa041140.80804637
65Phototransduction_Homo sapiens_hsa047440.79277974
66Huntingtons disease_Homo sapiens_hsa050160.78588420
67Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.76763839
68Phospholipase D signaling pathway_Homo sapiens_hsa040720.74616181
69MAPK signaling pathway_Homo sapiens_hsa040100.74425387
70Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.73899766
71alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.71800028
72Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.71286160
73Dilated cardiomyopathy_Homo sapiens_hsa054140.70773949
74Pancreatic secretion_Homo sapiens_hsa049720.70189767
75Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.69896063
76Thyroid hormone synthesis_Homo sapiens_hsa049180.68964149
77Basal transcription factors_Homo sapiens_hsa030220.68098652
78Choline metabolism in cancer_Homo sapiens_hsa052310.67837937
79RNA degradation_Homo sapiens_hsa030180.67763149
80Ras signaling pathway_Homo sapiens_hsa040140.64027114
81Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.62408463
82Type I diabetes mellitus_Homo sapiens_hsa049400.60619094
83Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.59556165
84Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.58087546
85Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.57940584
86Carbohydrate digestion and absorption_Homo sapiens_hsa049730.54967281
87Glucagon signaling pathway_Homo sapiens_hsa049220.53459444
88Neurotrophin signaling pathway_Homo sapiens_hsa047220.53228513
89Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.52803363
90Rap1 signaling pathway_Homo sapiens_hsa040150.52670127
91Circadian rhythm_Homo sapiens_hsa047100.52378005
92Tryptophan metabolism_Homo sapiens_hsa003800.52322216
93VEGF signaling pathway_Homo sapiens_hsa043700.52040992
94RNA polymerase_Homo sapiens_hsa030200.51930243
95Thyroid hormone signaling pathway_Homo sapiens_hsa049190.49994427
96Endocytosis_Homo sapiens_hsa041440.49970651
97Sphingolipid signaling pathway_Homo sapiens_hsa040710.48306960
98Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.48123284
99Steroid biosynthesis_Homo sapiens_hsa001000.48092706
100Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.47675648
101Bile secretion_Homo sapiens_hsa049760.46891939
102Ovarian steroidogenesis_Homo sapiens_hsa049130.46597955
103SNARE interactions in vesicular transport_Homo sapiens_hsa041300.46227283
104Inositol phosphate metabolism_Homo sapiens_hsa005620.45347252
105Prion diseases_Homo sapiens_hsa050200.45201903
106mTOR signaling pathway_Homo sapiens_hsa041500.44905784
107Endometrial cancer_Homo sapiens_hsa052130.44660193
108Renal cell carcinoma_Homo sapiens_hsa052110.43738931
109Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.41410226
110Wnt signaling pathway_Homo sapiens_hsa043100.41305957
111Alcoholism_Homo sapiens_hsa050340.41217635
112Insulin signaling pathway_Homo sapiens_hsa049100.40730512
113Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.38141992
114beta-Alanine metabolism_Homo sapiens_hsa004100.37769648
115Longevity regulating pathway - mammal_Homo sapiens_hsa042110.36545486
116Fatty acid elongation_Homo sapiens_hsa000620.35629614
117Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.35625631
118Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.35492116
119Non-small cell lung cancer_Homo sapiens_hsa052230.33270568
120Rheumatoid arthritis_Homo sapiens_hsa053230.32432093
121Phenylalanine metabolism_Homo sapiens_hsa003600.32032144
122Selenocompound metabolism_Homo sapiens_hsa004500.30848835
123Peroxisome_Homo sapiens_hsa041460.30773167
124Chemokine signaling pathway_Homo sapiens_hsa040620.30202549
125Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.28674107
126Fatty acid biosynthesis_Homo sapiens_hsa000610.28301108
127Colorectal cancer_Homo sapiens_hsa052100.27812174
128Arginine biosynthesis_Homo sapiens_hsa002200.27439202
129Propanoate metabolism_Homo sapiens_hsa006400.27317742
130Caffeine metabolism_Homo sapiens_hsa002320.27265299
131Fanconi anemia pathway_Homo sapiens_hsa034600.26956558
132Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.26878142
133Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.25779845
134Hedgehog signaling pathway_Homo sapiens_hsa043400.25192158
135Arginine and proline metabolism_Homo sapiens_hsa003300.22524717
136Primary bile acid biosynthesis_Homo sapiens_hsa001200.20489269

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