Rank | Gene Set | Z-score |
---|---|---|
1 | retinal rod cell development (GO:0046548) | 8.61486887 |
2 | detection of light stimulus involved in visual perception (GO:0050908) | 8.25895308 |
3 | detection of light stimulus involved in sensory perception (GO:0050962) | 8.25895308 |
4 | retinal cone cell development (GO:0046549) | 6.58594745 |
5 | protein localization to synapse (GO:0035418) | 6.50922882 |
6 | centriole replication (GO:0007099) | 5.88437890 |
7 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 5.88236836 |
8 | photoreceptor cell development (GO:0042461) | 5.43551951 |
9 | eye photoreceptor cell development (GO:0042462) | 5.38649252 |
10 | photoreceptor cell maintenance (GO:0045494) | 5.33864534 |
11 | positive regulation of histone H3-K4 methylation (GO:0051571) | 5.31263273 |
12 | multicellular organism reproduction (GO:0032504) | 5.26067703 |
13 | regulation of histone H3-K9 methylation (GO:0051570) | 5.25710095 |
14 | synaptic vesicle exocytosis (GO:0016079) | 5.22996766 |
15 | cellular potassium ion homeostasis (GO:0030007) | 5.21027267 |
16 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 5.08774849 |
17 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 4.93445947 |
18 | oocyte development (GO:0048599) | 4.93437694 |
19 | gene silencing by RNA (GO:0031047) | 4.85079549 |
20 | rhodopsin mediated signaling pathway (GO:0016056) | 4.80760182 |
21 | protein-chromophore linkage (GO:0018298) | 4.79146266 |
22 | positive regulation of sodium ion transmembrane transporter activity (GO:2000651) | 4.78783680 |
23 | glycine transport (GO:0015816) | 4.67636304 |
24 | regulation of steroid hormone secretion (GO:2000831) | 4.64212009 |
25 | piRNA metabolic process (GO:0034587) | 4.62939354 |
26 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 4.57497971 |
27 | synaptic vesicle endocytosis (GO:0048488) | 4.48368825 |
28 | interkinetic nuclear migration (GO:0022027) | 4.47189706 |
29 | regulation of acrosome reaction (GO:0060046) | 4.45228868 |
30 | behavioral response to ethanol (GO:0048149) | 4.42718225 |
31 | positive regulation of sodium ion transmembrane transport (GO:1902307) | 4.40026363 |
32 | sodium ion export (GO:0071436) | 4.37527813 |
33 | negative regulation of reproductive process (GO:2000242) | 4.36613968 |
34 | potassium ion homeostasis (GO:0055075) | 4.34830441 |
35 | relaxation of smooth muscle (GO:0044557) | 4.28994114 |
36 | regulation of female gonad development (GO:2000194) | 4.28697214 |
37 | translesion synthesis (GO:0019985) | 4.18679036 |
38 | primitive streak formation (GO:0090009) | 4.14804459 |
39 | male meiosis I (GO:0007141) | 4.08839037 |
40 | somite rostral/caudal axis specification (GO:0032525) | 4.08212025 |
41 | negative regulation of meiosis (GO:0045835) | 4.03788952 |
42 | synapsis (GO:0007129) | 4.00836077 |
43 | regulation of voltage-gated calcium channel activity (GO:1901385) | 3.97201777 |
44 | protein kinase C signaling (GO:0070528) | 3.95144550 |
45 | regulation of meiosis (GO:0040020) | 3.93537689 |
46 | negative regulation of receptor-mediated endocytosis (GO:0048261) | 3.93138181 |
47 | neuroblast proliferation (GO:0007405) | 3.91955960 |
48 | centriole assembly (GO:0098534) | 3.87874918 |
49 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.87771566 |
50 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.87771566 |
51 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.87771566 |
52 | negative regulation of histone methylation (GO:0031061) | 3.83884311 |
53 | CENP-A containing nucleosome assembly (GO:0034080) | 3.82525684 |
54 | exploration behavior (GO:0035640) | 3.76329710 |
55 | negative regulation of cAMP-mediated signaling (GO:0043951) | 3.74689107 |
56 | dopamine biosynthetic process (GO:0042416) | 3.71392779 |
57 | detection of visible light (GO:0009584) | 3.70954892 |
58 | visual perception (GO:0007601) | 3.69912248 |
59 | oogenesis (GO:0048477) | 3.69724670 |
60 | innervation (GO:0060384) | 3.67463133 |
61 | sensory perception of light stimulus (GO:0050953) | 3.64550853 |
62 | protein localization to kinetochore (GO:0034501) | 3.62706171 |
63 | detection of light stimulus (GO:0009583) | 3.62415592 |
64 | female gamete generation (GO:0007292) | 3.61247869 |
65 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.60966646 |
66 | tachykinin receptor signaling pathway (GO:0007217) | 3.59279711 |
67 | photoreceptor cell differentiation (GO:0046530) | 3.59174213 |
68 | eye photoreceptor cell differentiation (GO:0001754) | 3.59174213 |
69 | regulation of clathrin-mediated endocytosis (GO:2000369) | 3.58152471 |
70 | chromatin remodeling at centromere (GO:0031055) | 3.57119173 |
71 | potassium ion export (GO:0071435) | 3.56687967 |
72 | phosphorelay signal transduction system (GO:0000160) | 3.55785117 |
73 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.55725494 |
74 | regulation of DNA methylation (GO:0044030) | 3.54800598 |
75 | regulation of synaptic vesicle transport (GO:1902803) | 3.50643297 |
76 | male meiosis (GO:0007140) | 3.48031952 |
77 | microtubule severing (GO:0051013) | 3.44721851 |
78 | protein localization to chromosome, centromeric region (GO:0071459) | 3.44177554 |
79 | regulation of synaptic vesicle exocytosis (GO:2000300) | 3.44157406 |
80 | base-excision repair, AP site formation (GO:0006285) | 3.43717020 |
81 | regulation of cell maturation (GO:1903429) | 3.42875562 |
82 | meiosis I (GO:0007127) | 3.40643704 |
83 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.39675976 |
84 | phospholipase C-activating dopamine receptor signaling pathway (GO:0060158) | 3.39127713 |
85 | fertilization (GO:0009566) | 3.38914251 |
86 | chromosome organization involved in meiosis (GO:0070192) | 3.37747698 |
87 | positive regulation of microtubule polymerization (GO:0031116) | 3.35151288 |
88 | estrogen biosynthetic process (GO:0006703) | 3.34788925 |
89 | reproduction (GO:0000003) | 3.33395996 |
90 | establishment of chromosome localization (GO:0051303) | 3.33368605 |
91 | nonmotile primary cilium assembly (GO:0035058) | 3.31554377 |
92 | centrosome duplication (GO:0051298) | 3.31000179 |
93 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.30666903 |
94 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 3.30220379 |
95 | synaptonemal complex assembly (GO:0007130) | 3.29895991 |
96 | L-amino acid import (GO:0043092) | 3.25663872 |
97 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 3.23017484 |
98 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 3.23017484 |
99 | sialylation (GO:0097503) | 3.22228607 |
100 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.21347635 |
101 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 3.19919811 |
102 | regulation of transforming growth factor beta2 production (GO:0032909) | 3.19522574 |
103 | DNA alkylation (GO:0006305) | 3.18789864 |
104 | DNA methylation (GO:0006306) | 3.18789864 |
105 | mitotic metaphase plate congression (GO:0007080) | 3.18442210 |
106 | positive regulation of humoral immune response (GO:0002922) | 3.18012288 |
107 | membrane hyperpolarization (GO:0060081) | 3.17881791 |
108 | negative regulation of meiotic cell cycle (GO:0051447) | 3.16004743 |
109 | apical protein localization (GO:0045176) | 3.14923117 |
110 | meiotic nuclear division (GO:0007126) | 3.14891313 |
111 | meiotic cell cycle (GO:0051321) | 3.14417077 |
112 | histone H2A monoubiquitination (GO:0035518) | 3.13712858 |
113 | neuron fate determination (GO:0048664) | 3.13499093 |
114 | regulation of meiotic cell cycle (GO:0051445) | 3.13115134 |
115 | positive regulation of histone methylation (GO:0031062) | 3.12591053 |
116 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.11737610 |
117 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.11737610 |
118 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.11108275 |
119 | positive regulation of synapse maturation (GO:0090129) | 3.09864178 |
120 | behavioral response to nicotine (GO:0035095) | 3.09005953 |
121 | positive regulation of TOR signaling (GO:0032008) | 3.08985616 |
122 | meiotic cell cycle process (GO:1903046) | 3.08623785 |
123 | postreplication repair (GO:0006301) | 3.08202637 |
124 | phototransduction (GO:0007602) | 3.07685144 |
125 | regulation of calcium ion-dependent exocytosis (GO:0017158) | 3.06750433 |
126 | DNA damage induced protein phosphorylation (GO:0006975) | 3.05454409 |
127 | calcium ion import (GO:0070509) | 3.05188585 |
128 | histone exchange (GO:0043486) | 3.04583219 |
129 | phototransduction, visible light (GO:0007603) | 3.02199785 |
130 | C21-steroid hormone biosynthetic process (GO:0006700) | 3.01935728 |
131 | regulation of histone H3-K4 methylation (GO:0051569) | 3.00978360 |
132 | vocalization behavior (GO:0071625) | 3.00605039 |
133 | regulation of hypersensitivity (GO:0002883) | 2.99556325 |
134 | aggressive behavior (GO:0002118) | 2.97730425 |
135 | chaperone-mediated protein transport (GO:0072321) | 2.96051370 |
136 | synaptic vesicle transport (GO:0048489) | 2.95630383 |
137 | establishment of synaptic vesicle localization (GO:0097480) | 2.95630383 |
138 | cellular response to light stimulus (GO:0071482) | 2.95123704 |
139 | striatum development (GO:0021756) | 2.94920845 |
140 | protein localization to chromosome (GO:0034502) | 2.94423882 |
141 | DNA replication-independent nucleosome organization (GO:0034724) | 2.94315563 |
142 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.94315563 |
143 | gene silencing (GO:0016458) | 2.90713081 |
144 | cellular ketone body metabolic process (GO:0046950) | 2.89243595 |
145 | synaptonemal complex organization (GO:0070193) | 2.88361832 |
146 | mitotic G2/M transition checkpoint (GO:0044818) | 2.88279431 |
147 | regulation of chromatin silencing (GO:0031935) | 2.88159807 |
148 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.87140226 |
149 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.87140226 |
150 | retina development in camera-type eye (GO:0060041) | 2.85862121 |
151 | regulation of receptor internalization (GO:0002090) | 2.85498596 |
152 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 2.85047113 |
153 | long-term synaptic potentiation (GO:0060291) | 2.85043105 |
154 | snRNA transcription (GO:0009301) | 2.84675788 |
155 | paraxial mesoderm development (GO:0048339) | 2.83536126 |
156 | positive regulation of chromosome segregation (GO:0051984) | 2.83115427 |
157 | pyrimidine dimer repair (GO:0006290) | 2.83051067 |
158 | positive regulation of microtubule polymerization or depolymerization (GO:0031112) | 2.80619758 |
159 | regulation of meiosis I (GO:0060631) | 2.80312487 |
160 | positive regulation of gastrulation (GO:2000543) | 2.78880567 |
161 | single fertilization (GO:0007338) | 2.78504855 |
162 | regulation of cell cycle G2/M phase transition (GO:1902749) | 2.78120461 |
163 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.77592660 |
164 | * gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.76514941 |
165 | relaxation of cardiac muscle (GO:0055119) | 2.74630899 |
166 | DNA methylation involved in gamete generation (GO:0043046) | 2.74193311 |
167 | detection of abiotic stimulus (GO:0009582) | 2.72156050 |
168 | regulation of G2/M transition of mitotic cell cycle (GO:0010389) | 2.71155352 |
169 | labyrinthine layer development (GO:0060711) | 2.70183789 |
170 | positive regulation of reproductive process (GO:2000243) | 2.70178146 |
171 | detection of external stimulus (GO:0009581) | 2.69785484 |
172 | regulation of histone H3-K27 methylation (GO:0061085) | 2.69422479 |
173 | histone H2A ubiquitination (GO:0033522) | 2.68676148 |
174 | atrial cardiac muscle cell action potential (GO:0086014) | 2.67754340 |
175 | histone H3-K9 demethylation (GO:0033169) | 2.65915268 |
176 | protein dealkylation (GO:0008214) | 2.65656464 |
177 | response to pheromone (GO:0019236) | 11.0483071 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 3.79917076 |
2 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 3.65233445 |
3 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 3.59415528 |
4 | IGF1R_20145208_ChIP-Seq_DFB_Human | 3.49723791 |
5 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 3.11464704 |
6 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.10949290 |
7 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 3.09360063 |
8 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.99456352 |
9 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.76204707 |
10 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 2.53523277 |
11 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.38713912 |
12 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.21949069 |
13 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.20125684 |
14 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.20048912 |
15 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.09382137 |
16 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.02221561 |
17 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 2.01554545 |
18 | EZH2_22144423_ChIP-Seq_EOC_Human | 10.4097665 |
19 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.94845814 |
20 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.92313477 |
21 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.91802700 |
22 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.88925687 |
23 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.88331304 |
24 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.87467574 |
25 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.86727615 |
26 | VDR_22108803_ChIP-Seq_LS180_Human | 1.86705181 |
27 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.81588461 |
28 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.80472870 |
29 | EWS_26573619_Chip-Seq_HEK293_Human | 1.73303704 |
30 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.72187786 |
31 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.69531423 |
32 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.66172047 |
33 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.65760533 |
34 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.59794476 |
35 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.56312983 |
36 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 1.55839378 |
37 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.55048437 |
38 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.52728826 |
39 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.52486688 |
40 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.50851827 |
41 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.50338982 |
42 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.49672575 |
43 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.49396116 |
44 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 1.48766166 |
45 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.48347042 |
46 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.47855639 |
47 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.46024513 |
48 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.45083063 |
49 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.42869961 |
50 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.42635233 |
51 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.42167209 |
52 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.40901346 |
53 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.40314001 |
54 | STAT3_23295773_ChIP-Seq_U87_Human | 1.39812658 |
55 | FUS_26573619_Chip-Seq_HEK293_Human | 1.38839609 |
56 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.37002257 |
57 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.36493146 |
58 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.36450231 |
59 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.35811188 |
60 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.35700122 |
61 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.35700122 |
62 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.35700122 |
63 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.34795769 |
64 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.34569413 |
65 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.32573876 |
66 | AR_25329375_ChIP-Seq_VCAP_Human | 1.31857239 |
67 | KDM2B_26808549_Chip-Seq_REH_Human | 1.31004625 |
68 | AR_19668381_ChIP-Seq_PC3_Human | 1.30925218 |
69 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.30494113 |
70 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.29210014 |
71 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.29170649 |
72 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.28455365 |
73 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.27391476 |
74 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.27210574 |
75 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.26415642 |
76 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.26255728 |
77 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.25162350 |
78 | TP53_16413492_ChIP-PET_HCT116_Human | 1.24984769 |
79 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 1.24182219 |
80 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.23501839 |
81 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.23328594 |
82 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.23180139 |
83 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.21354265 |
84 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.21212502 |
85 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.21154836 |
86 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.21154836 |
87 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.20330761 |
88 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.20037154 |
89 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.19871703 |
90 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.19264642 |
91 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.19258831 |
92 | P300_19829295_ChIP-Seq_ESCs_Human | 1.19053934 |
93 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.18896053 |
94 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.17903342 |
95 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.17676764 |
96 | TBL1_22424771_ChIP-Seq_293T_Human | 1.17250311 |
97 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.16764167 |
98 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.16764167 |
99 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.16155832 |
100 | TCF4_23295773_ChIP-Seq_U87_Human | 1.15804682 |
101 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.15401094 |
102 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.13835178 |
103 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.13683003 |
104 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.13579255 |
105 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.13265832 |
106 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.13265832 |
107 | * DROSHA_22980978_ChIP-Seq_HELA_Human | 1.13086398 |
108 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.12488248 |
109 | * TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.12060712 |
110 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.11103378 |
111 | * UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.10661322 |
112 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.07250163 |
113 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.07120714 |
114 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.06979511 |
115 | STAT1_17558387_ChIP-Seq_HELA_Human | 1.04468758 |
116 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.04215150 |
117 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.01994160 |
118 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.01247355 |
119 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.00901411 |
120 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.00856559 |
121 | NFYA_21822215_ChIP-Seq_K562_Human | 1.00335262 |
122 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.00117817 |
123 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.99989490 |
124 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.99912274 |
125 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.99680408 |
126 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.99320878 |
127 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.99226013 |
128 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.95634351 |
129 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.95574045 |
130 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.95383558 |
131 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.95267110 |
132 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.95054281 |
133 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.94537165 |
134 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.94281591 |
135 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.94172828 |
136 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.93613804 |
137 | * IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.93387956 |
138 | * CBP_20019798_ChIP-Seq_JUKART_Human | 0.93387956 |
139 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.93372877 |
140 | AR_20517297_ChIP-Seq_VCAP_Human | 0.93349216 |
141 | CBP_21632823_ChIP-Seq_H3396_Human | 0.93322109 |
142 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.93206306 |
143 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.93117932 |
144 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.93007092 |
145 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.92016808 |
146 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.91946105 |
147 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.91792363 |
148 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.91369904 |
149 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.91128127 |
150 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.91128127 |
151 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.90787895 |
152 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.90449597 |
153 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.90349057 |
154 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.90129869 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005551_abnormal_eye_electrophysiolog | 6.06905856 |
2 | MP0003950_abnormal_plasma_membrane | 5.49730930 |
3 | MP0003011_delayed_dark_adaptation | 5.08287172 |
4 | MP0006072_abnormal_retinal_apoptosis | 4.48182867 |
5 | MP0005253_abnormal_eye_physiology | 3.95977543 |
6 | MP0006292_abnormal_olfactory_placode | 3.36847251 |
7 | MP0002139_abnormal_hepatobiliary_system | 3.04880969 |
8 | MP0005360_urolithiasis | 3.01878669 |
9 | MP0002653_abnormal_ependyma_morphology | 2.97130386 |
10 | MP0001502_abnormal_circadian_rhythm | 2.87009751 |
11 | MP0002138_abnormal_hepatobiliary_system | 2.79051832 |
12 | MP0003718_maternal_effect | 2.71513936 |
13 | MP0005195_abnormal_posterior_eye | 2.71443733 |
14 | MP0002090_abnormal_vision | 2.70174724 |
15 | MP0001984_abnormal_olfaction | 2.68900051 |
16 | MP0008057_abnormal_DNA_replication | 2.67956812 |
17 | MP0004782_abnormal_surfactant_physiolog | 2.62652188 |
18 | MP0001346_abnormal_lacrimal_gland | 2.46836909 |
19 | MP0005451_abnormal_body_composition | 2.41606553 |
20 | MP0005248_abnormal_Harderian_gland | 2.17588114 |
21 | MP0003646_muscle_fatigue | 2.12383847 |
22 | MP0001324_abnormal_eye_pigmentation | 2.04192643 |
23 | MP0008789_abnormal_olfactory_epithelium | 2.02782613 |
24 | MP0005410_abnormal_fertilization | 1.96169226 |
25 | MP0005499_abnormal_olfactory_system | 1.96014636 |
26 | MP0005394_taste/olfaction_phenotype | 1.96014636 |
27 | MP0003252_abnormal_bile_duct | 1.95498009 |
28 | MP0004145_abnormal_muscle_electrophysio | 1.94791703 |
29 | MP0004215_abnormal_myocardial_fiber | 1.86246192 |
30 | MP0000631_abnormal_neuroendocrine_gland | 1.84469242 |
31 | MP0004233_abnormal_muscle_weight | 1.82141126 |
32 | MP0005647_abnormal_sex_gland | 1.78391525 |
33 | MP0005391_vision/eye_phenotype | 1.71123915 |
34 | MP0005670_abnormal_white_adipose | 1.69874056 |
35 | MP0003137_abnormal_impulse_conducting | 1.69631608 |
36 | MP0008058_abnormal_DNA_repair | 1.69447812 |
37 | MP0005085_abnormal_gallbladder_physiolo | 1.64994818 |
38 | MP0003880_abnormal_central_pattern | 1.62825846 |
39 | MP0002102_abnormal_ear_morphology | 1.61523563 |
40 | MP0002752_abnormal_somatic_nervous | 1.56882157 |
41 | MP0001486_abnormal_startle_reflex | 1.56017118 |
42 | MP0002160_abnormal_reproductive_system | 1.55972088 |
43 | MP0002229_neurodegeneration | 1.44975762 |
44 | MP0003699_abnormal_female_reproductive | 1.44282271 |
45 | MP0001529_abnormal_vocalization | 1.39515058 |
46 | MP0001661_extended_life_span | 1.39099282 |
47 | MP0006276_abnormal_autonomic_nervous | 1.38194576 |
48 | MP0009840_abnormal_foam_cell | 1.32758143 |
49 | MP0010030_abnormal_orbit_morphology | 1.31261501 |
50 | MP0008877_abnormal_DNA_methylation | 1.30008069 |
51 | MP0005646_abnormal_pituitary_gland | 1.24723093 |
52 | MP0002638_abnormal_pupillary_reflex | 1.24261788 |
53 | MP0004043_abnormal_pH_regulation | 1.23413767 |
54 | MP0005395_other_phenotype | 1.22688452 |
55 | MP0000751_myopathy | 1.21539481 |
56 | MP0004859_abnormal_synaptic_plasticity | 1.20516156 |
57 | MP0000427_abnormal_hair_cycle | 1.19998592 |
58 | MP0010386_abnormal_urinary_bladder | 1.16847069 |
59 | MP0003136_yellow_coat_color | 1.15598042 |
60 | MP0002882_abnormal_neuron_morphology | 1.14438522 |
61 | MP0001929_abnormal_gametogenesis | 1.13592083 |
62 | MP0001664_abnormal_digestion | 1.13504179 |
63 | MP0002734_abnormal_mechanical_nocicepti | 1.12334013 |
64 | MP0003635_abnormal_synaptic_transmissio | 1.11443475 |
65 | MP0002127_abnormal_cardiovascular_syste | 1.10796247 |
66 | MP0000465_gastrointestinal_hemorrhage | 1.08779888 |
67 | MP0008004_abnormal_stomach_pH | 1.08109197 |
68 | MP0003890_abnormal_embryonic-extraembry | 1.07399500 |
69 | MP0002063_abnormal_learning/memory/cond | 1.04285611 |
70 | MP0005423_abnormal_somatic_nervous | 1.03585472 |
71 | MP0005389_reproductive_system_phenotype | 1.02344531 |
72 | MP0005197_abnormal_uvea_morphology | 1.01905788 |
73 | MP0000653_abnormal_sex_gland | 1.00846747 |
74 | MP0003195_calcinosis | 0.99562498 |
75 | MP0001986_abnormal_taste_sensitivity | 0.99517838 |
76 | MP0010094_abnormal_chromosome_stability | 0.98270575 |
77 | MP0002161_abnormal_fertility/fecundity | 0.97010028 |
78 | MP0001293_anophthalmia | 0.96345023 |
79 | MP0009384_cardiac_valve_regurgitation | 0.93595407 |
80 | MP0000015_abnormal_ear_pigmentation | 0.93426174 |
81 | MP0001119_abnormal_female_reproductive | 0.93268682 |
82 | MP0004270_analgesia | 0.91003606 |
83 | MP0003698_abnormal_male_reproductive | 0.90162560 |
84 | MP0000639_abnormal_adrenal_gland | 0.89148486 |
85 | MP0002064_seizures | 0.88461362 |
86 | MP0002095_abnormal_skin_pigmentation | 0.87232436 |
87 | MP0000569_abnormal_digit_pigmentation | 0.87042627 |
88 | MP0005645_abnormal_hypothalamus_physiol | 0.86958812 |
89 | MP0002396_abnormal_hematopoietic_system | 0.86035873 |
90 | MP0009046_muscle_twitch | 0.85018525 |
91 | MP0009697_abnormal_copulation | 0.84428101 |
92 | MP0009672_abnormal_birth_weight | 0.84002098 |
93 | MP0008260_abnormal_autophagy | 0.83837076 |
94 | MP0002735_abnormal_chemical_nociception | 0.81152321 |
95 | MP0002332_abnormal_exercise_endurance | 0.80995423 |
96 | MP0010368_abnormal_lymphatic_system | 0.80045708 |
97 | MP0005075_abnormal_melanosome_morpholog | 0.79820691 |
98 | MP0002210_abnormal_sex_determination | 0.79738403 |
99 | MP0002067_abnormal_sensory_capabilities | 0.79724345 |
100 | MP0002272_abnormal_nervous_system | 0.79675586 |
101 | MP0002234_abnormal_pharynx_morphology | 0.79478763 |
102 | MP0003879_abnormal_hair_cell | 0.78337598 |
103 | MP0003693_abnormal_embryo_hatching | 0.78183012 |
104 | MP0002184_abnormal_innervation | 0.77582094 |
105 | MP0001968_abnormal_touch/_nociception | 0.75642612 |
106 | MP0000462_abnormal_digestive_system | 0.75247532 |
107 | MP0005174_abnormal_tail_pigmentation | 0.75245891 |
108 | MP0001666_abnormal_nutrient_absorption | 0.74917519 |
109 | MP0002572_abnormal_emotion/affect_behav | 0.74390172 |
110 | MP0003868_abnormal_feces_composition | 0.74358703 |
111 | MP0008995_early_reproductive_senescence | 0.73001248 |
112 | MP0003111_abnormal_nucleus_morphology | 0.72073732 |
113 | MP0004924_abnormal_behavior | 0.71430419 |
114 | MP0005386_behavior/neurological_phenoty | 0.71430419 |
115 | MP0000579_abnormal_nail_morphology | 0.71049133 |
116 | MP0005187_abnormal_penis_morphology | 0.70964715 |
117 | MP0002152_abnormal_brain_morphology | 0.70417593 |
118 | MP0003937_abnormal_limbs/digits/tail_de | 0.69330938 |
119 | MP0000955_abnormal_spinal_cord | 0.69149072 |
120 | MP0010307_abnormal_tumor_latency | 0.67508339 |
121 | MP0004142_abnormal_muscle_tone | 0.67501818 |
122 | MP0003183_abnormal_peptide_metabolism | 0.66750354 |
123 | MP0001145_abnormal_male_reproductive | 0.66684042 |
124 | MP0003119_abnormal_digestive_system | 0.64779725 |
125 | MP0002233_abnormal_nose_morphology | 0.64276594 |
126 | MP0002751_abnormal_autonomic_nervous | 0.64246962 |
127 | MP0001501_abnormal_sleep_pattern | 0.64147986 |
128 | MP0003077_abnormal_cell_cycle | 0.62909507 |
129 | MP0000372_irregular_coat_pigmentation | 0.62731672 |
130 | MP0001905_abnormal_dopamine_level | 0.62065597 |
131 | MP0009745_abnormal_behavioral_response | 0.61801686 |
132 | MP0002069_abnormal_eating/drinking_beha | 0.61217159 |
133 | MP0005408_hypopigmentation | 0.60269725 |
134 | MP0001764_abnormal_homeostasis | 0.59897132 |
135 | MP0002736_abnormal_nociception_after | 0.59804456 |
136 | MP0004019_abnormal_vitamin_homeostasis | 0.58669467 |
137 | MP0003861_abnormal_nervous_system | 0.58650152 |
138 | MP0003121_genomic_imprinting | 0.55817272 |
139 | MP0001963_abnormal_hearing_physiology | 0.55281252 |
140 | MP0002066_abnormal_motor_capabilities/c | 0.52507801 |
141 | MP0003045_fibrosis | 0.52400976 |
142 | MP0003634_abnormal_glial_cell | 0.49996127 |
143 | MP0005310_abnormal_salivary_gland | 0.49727882 |
144 | MP0008875_abnormal_xenobiotic_pharmacok | 0.48959823 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Central scotoma (HP:0000603) | 8.53368325 |
2 | Abnormality of macular pigmentation (HP:0008002) | 8.26618730 |
3 | Bony spicule pigmentary retinopathy (HP:0007737) | 6.67519060 |
4 | Abnormal rod and cone electroretinograms (HP:0008323) | 6.51946677 |
5 | Supernumerary spleens (HP:0009799) | 6.35194991 |
6 | Scotoma (HP:0000575) | 6.05226451 |
7 | Septo-optic dysplasia (HP:0100842) | 5.49264801 |
8 | Severe visual impairment (HP:0001141) | 5.45839955 |
9 | Decreased central vision (HP:0007663) | 5.16199851 |
10 | Cone-rod dystrophy (HP:0000548) | 4.81644074 |
11 | Pendular nystagmus (HP:0012043) | 4.75531753 |
12 | Chorioretinal atrophy (HP:0000533) | 4.74605387 |
13 | Dyschromatopsia (HP:0007641) | 4.65136036 |
14 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 4.60103833 |
15 | Attenuation of retinal blood vessels (HP:0007843) | 4.28617134 |
16 | Increased corneal curvature (HP:0100692) | 4.13074117 |
17 | Keratoconus (HP:0000563) | 4.13074117 |
18 | Pigmentary retinal degeneration (HP:0001146) | 4.03518906 |
19 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 3.90373938 |
20 | Facial hemangioma (HP:0000329) | 3.76142337 |
21 | Abolished electroretinogram (ERG) (HP:0000550) | 3.67284728 |
22 | Male infertility (HP:0003251) | 3.52299930 |
23 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 3.47646915 |
24 | Hypoplasia of the fovea (HP:0007750) | 3.47646915 |
25 | Oligodactyly (hands) (HP:0001180) | 3.42058387 |
26 | Hypophosphatemic rickets (HP:0004912) | 3.40792951 |
27 | Absent septum pellucidum (HP:0001331) | 3.34804449 |
28 | Abnormality of the fovea (HP:0000493) | 3.31320475 |
29 | Photophobia (HP:0000613) | 3.26360098 |
30 | Posterior subcapsular cataract (HP:0007787) | 3.24391475 |
31 | Impulsivity (HP:0100710) | 3.22063842 |
32 | Hyperglycinemia (HP:0002154) | 3.18965532 |
33 | Osteomalacia (HP:0002749) | 3.14080487 |
34 | Fair hair (HP:0002286) | 3.12004653 |
35 | Febrile seizures (HP:0002373) | 3.11485260 |
36 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 3.10730701 |
37 | Type II diabetes mellitus (HP:0005978) | 3.09236217 |
38 | Gonadotropin excess (HP:0000837) | 3.04836179 |
39 | Gait imbalance (HP:0002141) | 3.04677275 |
40 | Cholecystitis (HP:0001082) | 3.02452825 |
41 | Abnormal gallbladder physiology (HP:0012438) | 3.02452825 |
42 | Congenital primary aphakia (HP:0007707) | 3.02418868 |
43 | Median cleft lip (HP:0000161) | 3.02223227 |
44 | Epileptic encephalopathy (HP:0200134) | 2.98194560 |
45 | Capillary hemangiomas (HP:0005306) | 2.85092287 |
46 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.83057444 |
47 | Macular degeneration (HP:0000608) | 2.82756069 |
48 | Abnormality of the septum pellucidum (HP:0007375) | 2.77318720 |
49 | Abnormal ciliary motility (HP:0012262) | 2.76080593 |
50 | Bile duct proliferation (HP:0001408) | 2.74541139 |
51 | Abnormal biliary tract physiology (HP:0012439) | 2.74541139 |
52 | Gaze-evoked nystagmus (HP:0000640) | 2.69567657 |
53 | Oral leukoplakia (HP:0002745) | 2.67421687 |
54 | Short tibia (HP:0005736) | 2.66188779 |
55 | Anterior segment dysgenesis (HP:0007700) | 2.65895705 |
56 | Nephrogenic diabetes insipidus (HP:0009806) | 2.63916513 |
57 | Poor coordination (HP:0002370) | 2.63817367 |
58 | Medial flaring of the eyebrow (HP:0010747) | 2.60081650 |
59 | Oligodactyly (HP:0012165) | 2.57454448 |
60 | Azoospermia (HP:0000027) | 2.57119399 |
61 | Optic nerve hypoplasia (HP:0000609) | 2.55024599 |
62 | Congenital sensorineural hearing impairment (HP:0008527) | 2.54274687 |
63 | Papillary thyroid carcinoma (HP:0002895) | 2.53297729 |
64 | Infertility (HP:0000789) | 2.52589737 |
65 | Conjunctival telangiectasia (HP:0000524) | 2.50125199 |
66 | Retinitis pigmentosa (HP:0000510) | 2.48319596 |
67 | Subcapsular cataract (HP:0000523) | 2.46685299 |
68 | Unsteady gait (HP:0002317) | 2.43417284 |
69 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 2.42522648 |
70 | Intrahepatic cholestasis (HP:0001406) | 2.40247916 |
71 | Malnutrition (HP:0004395) | 2.38450888 |
72 | Constricted visual fields (HP:0001133) | 2.37403688 |
73 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.35820181 |
74 | Absent/shortened dynein arms (HP:0200106) | 2.35820181 |
75 | Growth hormone deficiency (HP:0000824) | 2.34693196 |
76 | Aplasia/Hypoplasia of the macula (HP:0008059) | 2.33518983 |
77 | Mutism (HP:0002300) | 2.31589125 |
78 | Lip pit (HP:0100267) | 2.26074806 |
79 | Abnormality of abdominal situs (HP:0011620) | 2.22811169 |
80 | Abdominal situs inversus (HP:0003363) | 2.22811169 |
81 | Colon cancer (HP:0003003) | 2.22491151 |
82 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.21145774 |
83 | Prostate neoplasm (HP:0100787) | 2.20130928 |
84 | Thyroid carcinoma (HP:0002890) | 2.19958295 |
85 | Metaphyseal irregularity (HP:0003025) | 2.19318733 |
86 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.18934811 |
87 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 2.13273769 |
88 | Thyroid-stimulating hormone excess (HP:0002925) | 2.13240476 |
89 | Choroideremia (HP:0001139) | 2.11439947 |
90 | Vaginal atresia (HP:0000148) | 2.10411382 |
91 | Hemiplegia (HP:0002301) | 2.09656492 |
92 | Genital tract atresia (HP:0001827) | 2.07198995 |
93 | Methylmalonic acidemia (HP:0002912) | 2.07068562 |
94 | Abnormal auditory evoked potentials (HP:0006958) | 2.06469780 |
95 | Abnormality of chromosome stability (HP:0003220) | 2.06404293 |
96 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.03479715 |
97 | Proximal tubulopathy (HP:0000114) | 2.01983076 |
98 | Generalized hypopigmentation of hair (HP:0011358) | 2.01932414 |
99 | Neoplasm of the oral cavity (HP:0100649) | 2.01039446 |
100 | Congenital stationary night blindness (HP:0007642) | 11.1272915 |
101 | Stomach cancer (HP:0012126) | 1.99987632 |
102 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 1.98656623 |
103 | Chorioretinal coloboma (HP:0000567) | 1.97755383 |
104 | Abnormal spermatogenesis (HP:0008669) | 1.95377519 |
105 | Bicornuate uterus (HP:0000813) | 1.95008992 |
106 | 3-Methylglutaconic aciduria (HP:0003535) | 1.94021153 |
107 | Rhinitis (HP:0012384) | 1.93903319 |
108 | Aplastic anemia (HP:0001915) | 1.93390842 |
109 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.92008600 |
110 | Medulloblastoma (HP:0002885) | 1.88699574 |
111 | Ileus (HP:0002595) | 1.87284789 |
112 | Myokymia (HP:0002411) | 1.87238739 |
113 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 1.86699776 |
114 | Muscle stiffness (HP:0003552) | 1.85318430 |
115 | Meckel diverticulum (HP:0002245) | 1.84535432 |
116 | Progressive cerebellar ataxia (HP:0002073) | 1.84248380 |
117 | Wrist flexion contracture (HP:0001239) | 1.82638882 |
118 | Acute lymphatic leukemia (HP:0006721) | 1.82567987 |
119 | Postural instability (HP:0002172) | 1.82199730 |
120 | Abnormality of B cell number (HP:0010975) | 1.80926381 |
121 | Ependymoma (HP:0002888) | 1.79755729 |
122 | Nephronophthisis (HP:0000090) | 1.79192922 |
123 | Abnormality of the ileum (HP:0001549) | 1.77475002 |
124 | Abnormality of the sella turcica (HP:0002679) | 1.75636368 |
125 | Horizontal nystagmus (HP:0000666) | 1.75487439 |
126 | Visual hallucinations (HP:0002367) | 1.75206960 |
127 | Tubulointerstitial nephritis (HP:0001970) | 1.74768028 |
128 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.71285655 |
129 | Abnormality of the parathyroid morphology (HP:0011766) | 1.68078472 |
130 | Abnormality of the fingertips (HP:0001211) | 1.67678597 |
131 | Dysdiadochokinesis (HP:0002075) | 1.67421967 |
132 | Astigmatism (HP:0000483) | 1.65795267 |
133 | Left ventricular hypertrophy (HP:0001712) | 1.65381994 |
134 | Adrenal hypoplasia (HP:0000835) | 1.64471880 |
135 | Cortical dysplasia (HP:0002539) | 1.61601310 |
136 | True hermaphroditism (HP:0010459) | 1.61072868 |
137 | Leiomyosarcoma (HP:0100243) | 1.59922961 |
138 | Uterine leiomyosarcoma (HP:0002891) | 1.59922961 |
139 | Torticollis (HP:0000473) | 1.58319127 |
140 | Albinism (HP:0001022) | 1.57997043 |
141 | Primary adrenal insufficiency (HP:0008207) | 1.56359502 |
142 | Insulin-resistant diabetes mellitus (HP:0000831) | 1.56271246 |
143 | Fetal akinesia sequence (HP:0001989) | 1.54622844 |
144 | Vitreoretinal degeneration (HP:0000655) | 1.54619115 |
145 | Molar tooth sign on MRI (HP:0002419) | 1.54152960 |
146 | Abnormality of midbrain morphology (HP:0002418) | 1.54152960 |
147 | Pancreatic fibrosis (HP:0100732) | 1.53031637 |
148 | Abnormality of the labia minora (HP:0012880) | 1.51051261 |
149 | Primary amenorrhea (HP:0000786) | 1.50914984 |
150 | Chromsome breakage (HP:0040012) | 1.49594445 |
151 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.47311624 |
152 | Abnormality of the astrocytes (HP:0100707) | 1.47217875 |
153 | Astrocytoma (HP:0009592) | 1.47217875 |
154 | Hirsutism (HP:0001007) | 1.47181948 |
155 | Pancreatic cysts (HP:0001737) | 1.46706108 |
156 | Arterial tortuosity (HP:0005116) | 1.45510639 |
157 | Broad foot (HP:0001769) | 1.43606305 |
158 | Atonic seizures (HP:0010819) | 1.39841036 |
159 | Flat capital femoral epiphysis (HP:0003370) | 1.39763697 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EPHA3 | 4.91329298 |
2 | NEK1 | 3.95558620 |
3 | FRK | 3.87063309 |
4 | PAK6 | 3.83773537 |
5 | LATS1 | 3.76077371 |
6 | LATS2 | 3.26882285 |
7 | MAP3K6 | 3.14055299 |
8 | TAOK3 | 3.08946708 |
9 | KSR2 | 2.82657552 |
10 | STK38L | 2.68995587 |
11 | NEK6 | 2.51027868 |
12 | PIK3CG | 2.30539743 |
13 | MOS | 2.29304758 |
14 | BMPR2 | 2.12757828 |
15 | ZAK | 2.03157043 |
16 | CDK8 | 2.02639137 |
17 | ERBB4 | 1.95488349 |
18 | MAP3K9 | 1.89602196 |
19 | RAF1 | 1.87887751 |
20 | BRAF | 1.87190075 |
21 | TRIM28 | 1.85393393 |
22 | PINK1 | 1.84414843 |
23 | STK38 | 1.81634408 |
24 | MAP4K2 | 1.76216176 |
25 | MET | 1.74002501 |
26 | EIF2AK3 | 1.71873568 |
27 | TTK | 1.70706866 |
28 | PBK | 1.68244654 |
29 | MAP2K7 | 1.67142918 |
30 | PLK4 | 1.59033760 |
31 | PRKD3 | 1.57510576 |
32 | EEF2K | 1.56346051 |
33 | MAP3K13 | 1.50487100 |
34 | PNCK | 1.49982086 |
35 | MAP3K4 | 1.42974526 |
36 | TNIK | 1.40474887 |
37 | BMPR1B | 1.35985348 |
38 | TNK2 | 1.35452574 |
39 | TAOK1 | 1.35385089 |
40 | KDR | 1.34781365 |
41 | MARK3 | 1.34750572 |
42 | CDC7 | 1.32410085 |
43 | CSNK1G3 | 1.31563327 |
44 | PRKCI | 1.30454456 |
45 | STK24 | 1.30053100 |
46 | GRK1 | 1.28724552 |
47 | CHEK2 | 1.26118921 |
48 | KSR1 | 1.26065350 |
49 | PRKD2 | 1.22574596 |
50 | PRPF4B | 1.22292616 |
51 | CDK9 | 1.20875605 |
52 | PKN1 | 1.19500086 |
53 | WNK3 | 1.13324336 |
54 | MUSK | 1.10228794 |
55 | OXSR1 | 1.06017433 |
56 | PIM1 | 1.05055078 |
57 | DYRK2 | 1.02950052 |
58 | CDK3 | 1.00835256 |
59 | PRKG2 | 1.00563303 |
60 | VRK1 | 1.00014257 |
61 | VRK2 | 0.99869219 |
62 | SGK494 | 0.99118856 |
63 | SGK223 | 0.99118856 |
64 | GRK5 | 0.98570578 |
65 | PHKG1 | 0.98062221 |
66 | PHKG2 | 0.98062221 |
67 | ARAF | 0.95870939 |
68 | MAPK13 | 0.94453682 |
69 | CDK19 | 0.94322036 |
70 | TIE1 | 0.93534645 |
71 | DYRK1A | 0.93493874 |
72 | CDK7 | 0.91600265 |
73 | TEC | 0.88019626 |
74 | FLT3 | 0.86748895 |
75 | CSNK1A1L | 0.85250024 |
76 | ADRBK2 | 0.83432704 |
77 | STK39 | 0.81332431 |
78 | RPS6KB2 | 0.80326343 |
79 | STK3 | 0.80283887 |
80 | NEK9 | 0.79196740 |
81 | PRKAA1 | 0.76746366 |
82 | SGK2 | 0.76671909 |
83 | MARK2 | 0.76524482 |
84 | CSF1R | 0.75001304 |
85 | DMPK | 0.74486572 |
86 | PLK1 | 0.73096333 |
87 | NEK2 | 0.72769872 |
88 | CCNB1 | 0.72143305 |
89 | AKT3 | 0.70377956 |
90 | MAP3K12 | 0.69298371 |
91 | PRKAA2 | 0.68876339 |
92 | MAP2K4 | 0.68248195 |
93 | MELK | 0.67777760 |
94 | NTRK3 | 0.62830720 |
95 | RPS6KA4 | 0.60990689 |
96 | ACVR1B | 0.60261224 |
97 | MAP3K1 | 0.55199853 |
98 | NTRK2 | 0.53437579 |
99 | PLK3 | 0.52563718 |
100 | MAPK10 | 0.52451663 |
101 | MAPKAPK5 | 0.50735927 |
102 | MINK1 | 0.50720462 |
103 | AURKB | 0.48561577 |
104 | MAP3K7 | 0.48434209 |
105 | PRKACA | 0.47675178 |
106 | PRKACB | 0.47642980 |
107 | PAK3 | 0.47279015 |
108 | BRSK2 | 0.47113146 |
109 | SRPK1 | 0.46539932 |
110 | MARK1 | 0.45536158 |
111 | AURKA | 0.45167207 |
112 | TAOK2 | 0.44680333 |
113 | MST4 | 0.44428300 |
114 | ATM | 0.44331733 |
115 | RET | 0.42864533 |
116 | NUAK1 | 0.42164836 |
117 | CAMK2A | 0.40644408 |
118 | MAPKAPK3 | 0.40301933 |
119 | CDK15 | 0.40233950 |
120 | CDK1 | 0.38991609 |
121 | SGK3 | 0.38418415 |
122 | DYRK1B | 0.37380868 |
123 | WEE1 | 0.37350757 |
124 | GSK3B | 0.37344126 |
125 | CSNK1A1 | 0.37095650 |
126 | CAMK1 | 0.36228796 |
127 | MAPK14 | 0.36043269 |
128 | RPS6KA3 | 0.35823727 |
129 | CDK18 | 0.35442840 |
130 | INSRR | 0.34998011 |
131 | KIT | 0.34439277 |
132 | BCKDK | 0.34427454 |
133 | RPS6KA5 | 0.33572086 |
134 | GSK3A | 0.33456593 |
135 | EIF2AK2 | 0.33120302 |
136 | CDK11A | 0.32358226 |
137 | HIPK2 | 0.32292763 |
138 | CDK5 | 0.32170105 |
139 | CDK14 | 0.32122895 |
140 | CSNK1G1 | 0.32036230 |
141 | CSNK1G2 | 0.31455104 |
142 | LMTK2 | 0.31167569 |
143 | PLK2 | 0.31133694 |
144 | ERBB2 | 0.30771687 |
145 | MAP3K5 | 0.30629888 |
146 | PRKG1 | 0.30468374 |
147 | CHEK1 | 0.29682642 |
148 | MAPK9 | 0.29393441 |
149 | SGK1 | 0.28370026 |
150 | AKT1 | 0.27476070 |
151 | CSNK1D | 0.26879184 |
152 | ATR | 0.26692005 |
153 | CSNK1E | 0.25639902 |
154 | CDK2 | 0.24186386 |
155 | BRSK1 | 0.22446137 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Phototransduction_Homo sapiens_hsa04744 | 5.49174759 |
2 | Circadian rhythm_Homo sapiens_hsa04710 | 3.71805703 |
3 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.60454931 |
4 | * Nicotine addiction_Homo sapiens_hsa05033 | 3.10208850 |
5 | Caffeine metabolism_Homo sapiens_hsa00232 | 3.03712725 |
6 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.74277010 |
7 | Mismatch repair_Homo sapiens_hsa03430 | 2.63267902 |
8 | * GABAergic synapse_Homo sapiens_hsa04727 | 2.62151901 |
9 | * Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.36025945 |
10 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.26441017 |
11 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 2.02711208 |
12 | Circadian entrainment_Homo sapiens_hsa04713 | 1.89468346 |
13 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.85365716 |
14 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.78739711 |
15 | * Morphine addiction_Homo sapiens_hsa05032 | 1.76775719 |
16 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.73123946 |
17 | RNA degradation_Homo sapiens_hsa03018 | 1.71935566 |
18 | DNA replication_Homo sapiens_hsa03030 | 1.67203649 |
19 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.64658078 |
20 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.60517127 |
21 | Cell cycle_Homo sapiens_hsa04110 | 1.60025417 |
22 | Insulin secretion_Homo sapiens_hsa04911 | 1.57795728 |
23 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.52392187 |
24 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.50161542 |
25 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.46495015 |
26 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.45337715 |
27 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.45139155 |
28 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.42409731 |
29 | Basal transcription factors_Homo sapiens_hsa03022 | 1.39138147 |
30 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.37660035 |
31 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.33971183 |
32 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.32999832 |
33 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.32702115 |
34 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.32075286 |
35 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.30110000 |
36 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.26271823 |
37 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.24773564 |
38 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.23312980 |
39 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.21755789 |
40 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.19572603 |
41 | Asthma_Homo sapiens_hsa05310 | 1.16932971 |
42 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.14077290 |
43 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.12952364 |
44 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.11428107 |
45 | Salivary secretion_Homo sapiens_hsa04970 | 1.11382512 |
46 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.08860496 |
47 | Olfactory transduction_Homo sapiens_hsa04740 | 1.07793373 |
48 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.04660881 |
49 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.04288146 |
50 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.03390239 |
51 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.01314567 |
52 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.98588516 |
53 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.98000080 |
54 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.97186864 |
55 | Huntingtons disease_Homo sapiens_hsa05016 | 0.96640957 |
56 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.94808012 |
57 | Colorectal cancer_Homo sapiens_hsa05210 | 0.94347466 |
58 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.93327718 |
59 | Purine metabolism_Homo sapiens_hsa00230 | 0.92384675 |
60 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.91208477 |
61 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.91159200 |
62 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.89188578 |
63 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.89161482 |
64 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.88910568 |
65 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.87995667 |
66 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.87845259 |
67 | Histidine metabolism_Homo sapiens_hsa00340 | 0.87659775 |
68 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.86879392 |
69 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.86571441 |
70 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.85969817 |
71 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.83063019 |
72 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.81514834 |
73 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.80840144 |
74 | Renin secretion_Homo sapiens_hsa04924 | 0.80511309 |
75 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.80064311 |
76 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.79081044 |
77 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.78335301 |
78 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.75399329 |
79 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.74683887 |
80 | Long-term depression_Homo sapiens_hsa04730 | 0.74048490 |
81 | Endometrial cancer_Homo sapiens_hsa05213 | 0.73972889 |
82 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.73190307 |
83 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.72683564 |
84 | Base excision repair_Homo sapiens_hsa03410 | 0.71834562 |
85 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.68103806 |
86 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.66850009 |
87 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.65464384 |
88 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.64603260 |
89 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.64367920 |
90 | Parkinsons disease_Homo sapiens_hsa05012 | 0.63715516 |
91 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.63544211 |
92 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.61624828 |
93 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.60213281 |
94 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.59617218 |
95 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.57790589 |
96 | Retinol metabolism_Homo sapiens_hsa00830 | 0.56341136 |
97 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.56306329 |
98 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.56203934 |
99 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.55651703 |
100 | Platelet activation_Homo sapiens_hsa04611 | 0.53589521 |
101 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.53527086 |
102 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.52253127 |
103 | * Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.48701677 |
104 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.47514683 |
105 | ABC transporters_Homo sapiens_hsa02010 | 0.47271712 |
106 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.47028227 |
107 | Taste transduction_Homo sapiens_hsa04742 | 0.46684344 |
108 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.46662828 |
109 | Allograft rejection_Homo sapiens_hsa05330 | 0.46634010 |
110 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.45978281 |
111 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.45849980 |
112 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.45151737 |
113 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.44565869 |
114 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.44196479 |
115 | Homologous recombination_Homo sapiens_hsa03440 | 0.43047533 |
116 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.42977364 |
117 | Gap junction_Homo sapiens_hsa04540 | 0.42787258 |
118 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.42700284 |
119 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.42391324 |
120 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.41508180 |
121 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.41503465 |
122 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.40865932 |
123 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.39262106 |
124 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.39241199 |
125 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.38686244 |
126 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.37516036 |
127 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.36866653 |
128 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.36072933 |
129 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.35697469 |
130 | Metabolic pathways_Homo sapiens_hsa01100 | 0.35628905 |
131 | Mineral absorption_Homo sapiens_hsa04978 | 0.35330557 |
132 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.34539387 |
133 | Melanoma_Homo sapiens_hsa05218 | 0.33901907 |
134 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.32798102 |
135 | RNA polymerase_Homo sapiens_hsa03020 | 0.32605384 |
136 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.32249969 |
137 | Long-term potentiation_Homo sapiens_hsa04720 | 0.31626966 |
138 | Bile secretion_Homo sapiens_hsa04976 | 0.29616559 |
139 | RNA transport_Homo sapiens_hsa03013 | 0.29430551 |
140 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.29002547 |
141 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.28951865 |
142 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.28655936 |
143 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.28533583 |
144 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.28298864 |
145 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.25064076 |
146 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.24596125 |
147 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.24485163 |
148 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.23157099 |
149 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.21937541 |
150 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.20971819 |