GABRR3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1retinal rod cell development (GO:0046548)8.61486887
2detection of light stimulus involved in visual perception (GO:0050908)8.25895308
3detection of light stimulus involved in sensory perception (GO:0050962)8.25895308
4retinal cone cell development (GO:0046549)6.58594745
5protein localization to synapse (GO:0035418)6.50922882
6centriole replication (GO:0007099)5.88437890
7positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.88236836
8photoreceptor cell development (GO:0042461)5.43551951
9eye photoreceptor cell development (GO:0042462)5.38649252
10photoreceptor cell maintenance (GO:0045494)5.33864534
11positive regulation of histone H3-K4 methylation (GO:0051571)5.31263273
12multicellular organism reproduction (GO:0032504)5.26067703
13regulation of histone H3-K9 methylation (GO:0051570)5.25710095
14synaptic vesicle exocytosis (GO:0016079)5.22996766
15cellular potassium ion homeostasis (GO:0030007)5.21027267
16regulation of inhibitory postsynaptic membrane potential (GO:0060080)5.08774849
17regulation of rhodopsin mediated signaling pathway (GO:0022400)4.93445947
18oocyte development (GO:0048599)4.93437694
19gene silencing by RNA (GO:0031047)4.85079549
20rhodopsin mediated signaling pathway (GO:0016056)4.80760182
21protein-chromophore linkage (GO:0018298)4.79146266
22positive regulation of sodium ion transmembrane transporter activity (GO:2000651)4.78783680
23glycine transport (GO:0015816)4.67636304
24regulation of steroid hormone secretion (GO:2000831)4.64212009
25piRNA metabolic process (GO:0034587)4.62939354
26negative regulation of cytosolic calcium ion concentration (GO:0051481)4.57497971
27synaptic vesicle endocytosis (GO:0048488)4.48368825
28interkinetic nuclear migration (GO:0022027)4.47189706
29regulation of acrosome reaction (GO:0060046)4.45228868
30behavioral response to ethanol (GO:0048149)4.42718225
31positive regulation of sodium ion transmembrane transport (GO:1902307)4.40026363
32sodium ion export (GO:0071436)4.37527813
33negative regulation of reproductive process (GO:2000242)4.36613968
34potassium ion homeostasis (GO:0055075)4.34830441
35relaxation of smooth muscle (GO:0044557)4.28994114
36regulation of female gonad development (GO:2000194)4.28697214
37translesion synthesis (GO:0019985)4.18679036
38primitive streak formation (GO:0090009)4.14804459
39male meiosis I (GO:0007141)4.08839037
40somite rostral/caudal axis specification (GO:0032525)4.08212025
41negative regulation of meiosis (GO:0045835)4.03788952
42synapsis (GO:0007129)4.00836077
43regulation of voltage-gated calcium channel activity (GO:1901385)3.97201777
44protein kinase C signaling (GO:0070528)3.95144550
45regulation of meiosis (GO:0040020)3.93537689
46negative regulation of receptor-mediated endocytosis (GO:0048261)3.93138181
47neuroblast proliferation (GO:0007405)3.91955960
48centriole assembly (GO:0098534)3.87874918
49positive regulation of mitotic sister chromatid separation (GO:1901970)3.87771566
50positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.87771566
51positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.87771566
52negative regulation of histone methylation (GO:0031061)3.83884311
53CENP-A containing nucleosome assembly (GO:0034080)3.82525684
54exploration behavior (GO:0035640)3.76329710
55negative regulation of cAMP-mediated signaling (GO:0043951)3.74689107
56dopamine biosynthetic process (GO:0042416)3.71392779
57detection of visible light (GO:0009584)3.70954892
58visual perception (GO:0007601)3.69912248
59oogenesis (GO:0048477)3.69724670
60innervation (GO:0060384)3.67463133
61sensory perception of light stimulus (GO:0050953)3.64550853
62protein localization to kinetochore (GO:0034501)3.62706171
63detection of light stimulus (GO:0009583)3.62415592
64female gamete generation (GO:0007292)3.61247869
65epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.60966646
66tachykinin receptor signaling pathway (GO:0007217)3.59279711
67photoreceptor cell differentiation (GO:0046530)3.59174213
68eye photoreceptor cell differentiation (GO:0001754)3.59174213
69regulation of clathrin-mediated endocytosis (GO:2000369)3.58152471
70chromatin remodeling at centromere (GO:0031055)3.57119173
71potassium ion export (GO:0071435)3.56687967
72phosphorelay signal transduction system (GO:0000160)3.55785117
73pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.55725494
74regulation of DNA methylation (GO:0044030)3.54800598
75regulation of synaptic vesicle transport (GO:1902803)3.50643297
76male meiosis (GO:0007140)3.48031952
77microtubule severing (GO:0051013)3.44721851
78protein localization to chromosome, centromeric region (GO:0071459)3.44177554
79regulation of synaptic vesicle exocytosis (GO:2000300)3.44157406
80base-excision repair, AP site formation (GO:0006285)3.43717020
81regulation of cell maturation (GO:1903429)3.42875562
82meiosis I (GO:0007127)3.40643704
83cilium or flagellum-dependent cell motility (GO:0001539)3.39675976
84phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.39127713
85fertilization (GO:0009566)3.38914251
86chromosome organization involved in meiosis (GO:0070192)3.37747698
87positive regulation of microtubule polymerization (GO:0031116)3.35151288
88estrogen biosynthetic process (GO:0006703)3.34788925
89reproduction (GO:0000003)3.33395996
90establishment of chromosome localization (GO:0051303)3.33368605
91nonmotile primary cilium assembly (GO:0035058)3.31554377
92centrosome duplication (GO:0051298)3.31000179
93monoubiquitinated protein deubiquitination (GO:0035520)3.30666903
94positive regulation of uterine smooth muscle contraction (GO:0070474)3.30220379
95synaptonemal complex assembly (GO:0007130)3.29895991
96L-amino acid import (GO:0043092)3.25663872
97regulation of dopamine uptake involved in synaptic transmission (GO:0051584)3.23017484
98regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)3.23017484
99sialylation (GO:0097503)3.22228607
100G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.21347635
101regulation of short-term neuronal synaptic plasticity (GO:0048172)3.19919811
102regulation of transforming growth factor beta2 production (GO:0032909)3.19522574
103DNA alkylation (GO:0006305)3.18789864
104DNA methylation (GO:0006306)3.18789864
105mitotic metaphase plate congression (GO:0007080)3.18442210
106positive regulation of humoral immune response (GO:0002922)3.18012288
107membrane hyperpolarization (GO:0060081)3.17881791
108negative regulation of meiotic cell cycle (GO:0051447)3.16004743
109apical protein localization (GO:0045176)3.14923117
110meiotic nuclear division (GO:0007126)3.14891313
111meiotic cell cycle (GO:0051321)3.14417077
112histone H2A monoubiquitination (GO:0035518)3.13712858
113neuron fate determination (GO:0048664)3.13499093
114regulation of meiotic cell cycle (GO:0051445)3.13115134
115positive regulation of histone methylation (GO:0031062)3.12591053
116DNA replication-dependent nucleosome organization (GO:0034723)3.11737610
117DNA replication-dependent nucleosome assembly (GO:0006335)3.11737610
118pyrimidine nucleotide catabolic process (GO:0006244)3.11108275
119positive regulation of synapse maturation (GO:0090129)3.09864178
120behavioral response to nicotine (GO:0035095)3.09005953
121positive regulation of TOR signaling (GO:0032008)3.08985616
122meiotic cell cycle process (GO:1903046)3.08623785
123postreplication repair (GO:0006301)3.08202637
124phototransduction (GO:0007602)3.07685144
125regulation of calcium ion-dependent exocytosis (GO:0017158)3.06750433
126DNA damage induced protein phosphorylation (GO:0006975)3.05454409
127calcium ion import (GO:0070509)3.05188585
128histone exchange (GO:0043486)3.04583219
129phototransduction, visible light (GO:0007603)3.02199785
130C21-steroid hormone biosynthetic process (GO:0006700)3.01935728
131regulation of histone H3-K4 methylation (GO:0051569)3.00978360
132vocalization behavior (GO:0071625)3.00605039
133regulation of hypersensitivity (GO:0002883)2.99556325
134aggressive behavior (GO:0002118)2.97730425
135chaperone-mediated protein transport (GO:0072321)2.96051370
136synaptic vesicle transport (GO:0048489)2.95630383
137establishment of synaptic vesicle localization (GO:0097480)2.95630383
138cellular response to light stimulus (GO:0071482)2.95123704
139striatum development (GO:0021756)2.94920845
140protein localization to chromosome (GO:0034502)2.94423882
141DNA replication-independent nucleosome organization (GO:0034724)2.94315563
142DNA replication-independent nucleosome assembly (GO:0006336)2.94315563
143gene silencing (GO:0016458)2.90713081
144cellular ketone body metabolic process (GO:0046950)2.89243595
145synaptonemal complex organization (GO:0070193)2.88361832
146mitotic G2/M transition checkpoint (GO:0044818)2.88279431
147regulation of chromatin silencing (GO:0031935)2.88159807
148regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.87140226
149regulation of mitotic spindle checkpoint (GO:1903504)2.87140226
150retina development in camera-type eye (GO:0060041)2.85862121
151regulation of receptor internalization (GO:0002090)2.85498596
152cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.85047113
153long-term synaptic potentiation (GO:0060291)2.85043105
154snRNA transcription (GO:0009301)2.84675788
155paraxial mesoderm development (GO:0048339)2.83536126
156positive regulation of chromosome segregation (GO:0051984)2.83115427
157pyrimidine dimer repair (GO:0006290)2.83051067
158positive regulation of microtubule polymerization or depolymerization (GO:0031112)2.80619758
159regulation of meiosis I (GO:0060631)2.80312487
160positive regulation of gastrulation (GO:2000543)2.78880567
161single fertilization (GO:0007338)2.78504855
162regulation of cell cycle G2/M phase transition (GO:1902749)2.78120461
163attachment of spindle microtubules to kinetochore (GO:0008608)2.77592660
164* gamma-aminobutyric acid signaling pathway (GO:0007214)2.76514941
165relaxation of cardiac muscle (GO:0055119)2.74630899
166DNA methylation involved in gamete generation (GO:0043046)2.74193311
167detection of abiotic stimulus (GO:0009582)2.72156050
168regulation of G2/M transition of mitotic cell cycle (GO:0010389)2.71155352
169labyrinthine layer development (GO:0060711)2.70183789
170positive regulation of reproductive process (GO:2000243)2.70178146
171detection of external stimulus (GO:0009581)2.69785484
172regulation of histone H3-K27 methylation (GO:0061085)2.69422479
173histone H2A ubiquitination (GO:0033522)2.68676148
174atrial cardiac muscle cell action potential (GO:0086014)2.67754340
175histone H3-K9 demethylation (GO:0033169)2.65915268
176protein dealkylation (GO:0008214)2.65656464
177response to pheromone (GO:0019236)11.0483071

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.79917076
2GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse3.65233445
3SMAD_19615063_ChIP-ChIP_OVARY_Human3.59415528
4IGF1R_20145208_ChIP-Seq_DFB_Human3.49723791
5SALL1_21062744_ChIP-ChIP_HESCs_Human3.11464704
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.10949290
7ZFP322A_24550733_ChIP-Seq_MESCs_Mouse3.09360063
8HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.99456352
9GBX2_23144817_ChIP-Seq_PC3_Human2.76204707
10SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.53523277
11E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.38713912
12NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.21949069
13BP1_19119308_ChIP-ChIP_Hs578T_Human2.20125684
14TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.20048912
15CTBP2_25329375_ChIP-Seq_LNCAP_Human2.09382137
16POU3F2_20337985_ChIP-ChIP_501MEL_Human2.02221561
17P53_22127205_ChIP-Seq_FIBROBLAST_Human2.01554545
18EZH2_22144423_ChIP-Seq_EOC_Human10.4097665
19RNF2_27304074_Chip-Seq_NSC_Mouse1.94845814
20ZNF274_21170338_ChIP-Seq_K562_Hela1.92313477
21RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.91802700
22BMI1_23680149_ChIP-Seq_NPCS_Mouse1.88925687
23REST_21632747_ChIP-Seq_MESCs_Mouse1.88331304
24AR_21572438_ChIP-Seq_LNCaP_Human1.87467574
25TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.86727615
26VDR_22108803_ChIP-Seq_LS180_Human1.86705181
27MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.81588461
28MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.80472870
29EWS_26573619_Chip-Seq_HEK293_Human1.73303704
30GATA1_26923725_Chip-Seq_HPCs_Mouse1.72187786
31PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.69531423
32FLI1_27457419_Chip-Seq_LIVER_Mouse1.66172047
33CTBP1_25329375_ChIP-Seq_LNCAP_Human1.65760533
34E2F7_22180533_ChIP-Seq_HELA_Human1.59794476
35AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.56312983
36KAP1_22055183_ChIP-Seq_ESCs_Mouse1.55839378
37TAF15_26573619_Chip-Seq_HEK293_Human1.55048437
38SMAD4_21799915_ChIP-Seq_A2780_Human1.52728826
39ER_23166858_ChIP-Seq_MCF-7_Human1.52486688
40EZH2_27294783_Chip-Seq_ESCs_Mouse1.50851827
41SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.50338982
42REST_18959480_ChIP-ChIP_MESCs_Mouse1.49672575
43PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.49396116
44ELK4_26923725_Chip-Seq_MESODERM_Mouse1.48766166
45CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.48347042
46MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.47855639
47RNF2_27304074_Chip-Seq_ESCs_Mouse1.46024513
48IRF1_19129219_ChIP-ChIP_H3396_Human1.45083063
49JARID2_20064375_ChIP-Seq_MESCs_Mouse1.42869961
50CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.42635233
51PIAS1_25552417_ChIP-Seq_VCAP_Human1.42167209
52RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.40901346
53EZH2_27304074_Chip-Seq_ESCs_Mouse1.40314001
54STAT3_23295773_ChIP-Seq_U87_Human1.39812658
55FUS_26573619_Chip-Seq_HEK293_Human1.38839609
56CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.37002257
57MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.36493146
58MTF2_20144788_ChIP-Seq_MESCs_Mouse1.36450231
59TP63_19390658_ChIP-ChIP_HaCaT_Human1.35811188
60KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.35700122
61KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.35700122
62KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.35700122
63BCAT_22108803_ChIP-Seq_LS180_Human1.34795769
64ESR1_20079471_ChIP-ChIP_T-47D_Human1.34569413
65RUNX2_22187159_ChIP-Seq_PCA_Human1.32573876
66AR_25329375_ChIP-Seq_VCAP_Human1.31857239
67KDM2B_26808549_Chip-Seq_REH_Human1.31004625
68AR_19668381_ChIP-Seq_PC3_Human1.30925218
69SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.30494113
70GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.29210014
71HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.29170649
72SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.28455365
73KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.27391476
74ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.27210574
75FLI1_21867929_ChIP-Seq_TH2_Mouse1.26415642
76PCGF2_27294783_Chip-Seq_ESCs_Mouse1.26255728
77NOTCH1_21737748_ChIP-Seq_TLL_Human1.25162350
78TP53_16413492_ChIP-PET_HCT116_Human1.24984769
79CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.24182219
80RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.23501839
81EZH2_27294783_Chip-Seq_NPCs_Mouse1.23328594
82SMAD3_21741376_ChIP-Seq_EPCs_Human1.23180139
83NANOG_18555785_Chip-Seq_ESCs_Mouse1.21354265
84SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.21212502
85TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21154836
86POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.21154836
87TOP2B_26459242_ChIP-Seq_MCF-7_Human1.20330761
88JARID2_20075857_ChIP-Seq_MESCs_Mouse1.20037154
89SOX2_21211035_ChIP-Seq_LN229_Gbm1.19871703
90SMAD3_21741376_ChIP-Seq_HESCs_Human1.19264642
91PRDM14_20953172_ChIP-Seq_ESCs_Human1.19258831
92P300_19829295_ChIP-Seq_ESCs_Human1.19053934
93TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.18896053
94EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.17903342
95SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.17676764
96TBL1_22424771_ChIP-Seq_293T_Human1.17250311
97NANOG_19829295_ChIP-Seq_ESCs_Human1.16764167
98SOX2_19829295_ChIP-Seq_ESCs_Human1.16764167
99TCF4_22108803_ChIP-Seq_LS180_Human1.16155832
100TCF4_23295773_ChIP-Seq_U87_Human1.15804682
101SUZ12_27294783_Chip-Seq_ESCs_Mouse1.15401094
102TP53_22573176_ChIP-Seq_HFKS_Human1.13835178
103TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.13683003
104FOXM1_26456572_ChIP-Seq_MCF-7_Human1.13579255
105EZH2_18974828_ChIP-Seq_MESCs_Mouse1.13265832
106RNF2_18974828_ChIP-Seq_MESCs_Mouse1.13265832
107* DROSHA_22980978_ChIP-Seq_HELA_Human1.13086398
108ZFP57_27257070_Chip-Seq_ESCs_Mouse1.12488248
109* TAL1_26923725_Chip-Seq_HPCs_Mouse1.12060712
110TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.11103378
111* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.10661322
112YAP1_20516196_ChIP-Seq_MESCs_Mouse1.07250163
113LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.07120714
114MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.06979511
115STAT1_17558387_ChIP-Seq_HELA_Human1.04468758
116SMAD4_21741376_ChIP-Seq_EPCs_Human1.04215150
117FOXA1_21572438_ChIP-Seq_LNCaP_Human1.01994160
118RARB_27405468_Chip-Seq_BRAIN_Mouse1.01247355
119OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.00901411
120CDX2_22108803_ChIP-Seq_LS180_Human1.00856559
121NFYA_21822215_ChIP-Seq_K562_Human1.00335262
122NFE2_27457419_Chip-Seq_LIVER_Mouse1.00117817
123EP300_21415370_ChIP-Seq_HL-1_Mouse0.99989490
124ETV1_20927104_ChIP-Seq_GIST48_Human0.99912274
125STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.99680408
126NANOG_20526341_ChIP-Seq_ESCs_Human0.99320878
127NR3C1_21868756_ChIP-Seq_MCF10A_Human0.99226013
128EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.95634351
129EED_16625203_ChIP-ChIP_MESCs_Mouse0.95574045
130SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.95383558
131SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.95267110
132SMAD3_21741376_ChIP-Seq_ESCs_Human0.95054281
133HTT_18923047_ChIP-ChIP_STHdh_Human0.94537165
134FOXH1_21741376_ChIP-Seq_EPCs_Human0.94281591
135SMAD4_21741376_ChIP-Seq_HESCs_Human0.94172828
136LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93613804
137* IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.93387956
138* CBP_20019798_ChIP-Seq_JUKART_Human0.93387956
139SOX9_26525672_Chip-Seq_HEART_Mouse0.93372877
140AR_20517297_ChIP-Seq_VCAP_Human0.93349216
141CBP_21632823_ChIP-Seq_H3396_Human0.93322109
142SUZ12_27294783_Chip-Seq_NPCs_Mouse0.93206306
143KLF5_20875108_ChIP-Seq_MESCs_Mouse0.93117932
144CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.93007092
145SALL4_22934838_ChIP-ChIP_CD34+_Human0.92016808
146CRX_20693478_ChIP-Seq_RETINA_Mouse0.91946105
147AHR_22903824_ChIP-Seq_MCF-7_Human0.91792363
148EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.91369904
149FOXA1_25329375_ChIP-Seq_VCAP_Human0.91128127
150FOXA1_27270436_Chip-Seq_PROSTATE_Human0.91128127
151CDX2_19796622_ChIP-Seq_MESCs_Mouse0.90787895
152CMYC_18555785_Chip-Seq_ESCs_Mouse0.90449597
153GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.90349057
154RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.90129869

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005551_abnormal_eye_electrophysiolog6.06905856
2MP0003950_abnormal_plasma_membrane5.49730930
3MP0003011_delayed_dark_adaptation5.08287172
4MP0006072_abnormal_retinal_apoptosis4.48182867
5MP0005253_abnormal_eye_physiology3.95977543
6MP0006292_abnormal_olfactory_placode3.36847251
7MP0002139_abnormal_hepatobiliary_system3.04880969
8MP0005360_urolithiasis3.01878669
9MP0002653_abnormal_ependyma_morphology2.97130386
10MP0001502_abnormal_circadian_rhythm2.87009751
11MP0002138_abnormal_hepatobiliary_system2.79051832
12MP0003718_maternal_effect2.71513936
13MP0005195_abnormal_posterior_eye2.71443733
14MP0002090_abnormal_vision2.70174724
15MP0001984_abnormal_olfaction2.68900051
16MP0008057_abnormal_DNA_replication2.67956812
17MP0004782_abnormal_surfactant_physiolog2.62652188
18MP0001346_abnormal_lacrimal_gland2.46836909
19MP0005451_abnormal_body_composition2.41606553
20MP0005248_abnormal_Harderian_gland2.17588114
21MP0003646_muscle_fatigue2.12383847
22MP0001324_abnormal_eye_pigmentation2.04192643
23MP0008789_abnormal_olfactory_epithelium2.02782613
24MP0005410_abnormal_fertilization1.96169226
25MP0005499_abnormal_olfactory_system1.96014636
26MP0005394_taste/olfaction_phenotype1.96014636
27MP0003252_abnormal_bile_duct1.95498009
28MP0004145_abnormal_muscle_electrophysio1.94791703
29MP0004215_abnormal_myocardial_fiber1.86246192
30MP0000631_abnormal_neuroendocrine_gland1.84469242
31MP0004233_abnormal_muscle_weight1.82141126
32MP0005647_abnormal_sex_gland1.78391525
33MP0005391_vision/eye_phenotype1.71123915
34MP0005670_abnormal_white_adipose1.69874056
35MP0003137_abnormal_impulse_conducting1.69631608
36MP0008058_abnormal_DNA_repair1.69447812
37MP0005085_abnormal_gallbladder_physiolo1.64994818
38MP0003880_abnormal_central_pattern1.62825846
39MP0002102_abnormal_ear_morphology1.61523563
40MP0002752_abnormal_somatic_nervous1.56882157
41MP0001486_abnormal_startle_reflex1.56017118
42MP0002160_abnormal_reproductive_system1.55972088
43MP0002229_neurodegeneration1.44975762
44MP0003699_abnormal_female_reproductive1.44282271
45MP0001529_abnormal_vocalization1.39515058
46MP0001661_extended_life_span1.39099282
47MP0006276_abnormal_autonomic_nervous1.38194576
48MP0009840_abnormal_foam_cell1.32758143
49MP0010030_abnormal_orbit_morphology1.31261501
50MP0008877_abnormal_DNA_methylation1.30008069
51MP0005646_abnormal_pituitary_gland1.24723093
52MP0002638_abnormal_pupillary_reflex1.24261788
53MP0004043_abnormal_pH_regulation1.23413767
54MP0005395_other_phenotype1.22688452
55MP0000751_myopathy1.21539481
56MP0004859_abnormal_synaptic_plasticity1.20516156
57MP0000427_abnormal_hair_cycle1.19998592
58MP0010386_abnormal_urinary_bladder1.16847069
59MP0003136_yellow_coat_color1.15598042
60MP0002882_abnormal_neuron_morphology1.14438522
61MP0001929_abnormal_gametogenesis1.13592083
62MP0001664_abnormal_digestion1.13504179
63MP0002734_abnormal_mechanical_nocicepti1.12334013
64MP0003635_abnormal_synaptic_transmissio1.11443475
65MP0002127_abnormal_cardiovascular_syste1.10796247
66MP0000465_gastrointestinal_hemorrhage1.08779888
67MP0008004_abnormal_stomach_pH1.08109197
68MP0003890_abnormal_embryonic-extraembry1.07399500
69MP0002063_abnormal_learning/memory/cond1.04285611
70MP0005423_abnormal_somatic_nervous1.03585472
71MP0005389_reproductive_system_phenotype1.02344531
72MP0005197_abnormal_uvea_morphology1.01905788
73MP0000653_abnormal_sex_gland1.00846747
74MP0003195_calcinosis0.99562498
75MP0001986_abnormal_taste_sensitivity0.99517838
76MP0010094_abnormal_chromosome_stability0.98270575
77MP0002161_abnormal_fertility/fecundity0.97010028
78MP0001293_anophthalmia0.96345023
79MP0009384_cardiac_valve_regurgitation0.93595407
80MP0000015_abnormal_ear_pigmentation0.93426174
81MP0001119_abnormal_female_reproductive0.93268682
82MP0004270_analgesia0.91003606
83MP0003698_abnormal_male_reproductive0.90162560
84MP0000639_abnormal_adrenal_gland0.89148486
85MP0002064_seizures0.88461362
86MP0002095_abnormal_skin_pigmentation0.87232436
87MP0000569_abnormal_digit_pigmentation0.87042627
88MP0005645_abnormal_hypothalamus_physiol0.86958812
89MP0002396_abnormal_hematopoietic_system0.86035873
90MP0009046_muscle_twitch0.85018525
91MP0009697_abnormal_copulation0.84428101
92MP0009672_abnormal_birth_weight0.84002098
93MP0008260_abnormal_autophagy0.83837076
94MP0002735_abnormal_chemical_nociception0.81152321
95MP0002332_abnormal_exercise_endurance0.80995423
96MP0010368_abnormal_lymphatic_system0.80045708
97MP0005075_abnormal_melanosome_morpholog0.79820691
98MP0002210_abnormal_sex_determination0.79738403
99MP0002067_abnormal_sensory_capabilities0.79724345
100MP0002272_abnormal_nervous_system0.79675586
101MP0002234_abnormal_pharynx_morphology0.79478763
102MP0003879_abnormal_hair_cell0.78337598
103MP0003693_abnormal_embryo_hatching0.78183012
104MP0002184_abnormal_innervation0.77582094
105MP0001968_abnormal_touch/_nociception0.75642612
106MP0000462_abnormal_digestive_system0.75247532
107MP0005174_abnormal_tail_pigmentation0.75245891
108MP0001666_abnormal_nutrient_absorption0.74917519
109MP0002572_abnormal_emotion/affect_behav0.74390172
110MP0003868_abnormal_feces_composition0.74358703
111MP0008995_early_reproductive_senescence0.73001248
112MP0003111_abnormal_nucleus_morphology0.72073732
113MP0004924_abnormal_behavior0.71430419
114MP0005386_behavior/neurological_phenoty0.71430419
115MP0000579_abnormal_nail_morphology0.71049133
116MP0005187_abnormal_penis_morphology0.70964715
117MP0002152_abnormal_brain_morphology0.70417593
118MP0003937_abnormal_limbs/digits/tail_de0.69330938
119MP0000955_abnormal_spinal_cord0.69149072
120MP0010307_abnormal_tumor_latency0.67508339
121MP0004142_abnormal_muscle_tone0.67501818
122MP0003183_abnormal_peptide_metabolism0.66750354
123MP0001145_abnormal_male_reproductive0.66684042
124MP0003119_abnormal_digestive_system0.64779725
125MP0002233_abnormal_nose_morphology0.64276594
126MP0002751_abnormal_autonomic_nervous0.64246962
127MP0001501_abnormal_sleep_pattern0.64147986
128MP0003077_abnormal_cell_cycle0.62909507
129MP0000372_irregular_coat_pigmentation0.62731672
130MP0001905_abnormal_dopamine_level0.62065597
131MP0009745_abnormal_behavioral_response0.61801686
132MP0002069_abnormal_eating/drinking_beha0.61217159
133MP0005408_hypopigmentation0.60269725
134MP0001764_abnormal_homeostasis0.59897132
135MP0002736_abnormal_nociception_after0.59804456
136MP0004019_abnormal_vitamin_homeostasis0.58669467
137MP0003861_abnormal_nervous_system0.58650152
138MP0003121_genomic_imprinting0.55817272
139MP0001963_abnormal_hearing_physiology0.55281252
140MP0002066_abnormal_motor_capabilities/c0.52507801
141MP0003045_fibrosis0.52400976
142MP0003634_abnormal_glial_cell0.49996127
143MP0005310_abnormal_salivary_gland0.49727882
144MP0008875_abnormal_xenobiotic_pharmacok0.48959823

Predicted human phenotypes

RankGene SetZ-score
1Central scotoma (HP:0000603)8.53368325
2Abnormality of macular pigmentation (HP:0008002)8.26618730
3Bony spicule pigmentary retinopathy (HP:0007737)6.67519060
4Abnormal rod and cone electroretinograms (HP:0008323)6.51946677
5Supernumerary spleens (HP:0009799)6.35194991
6Scotoma (HP:0000575)6.05226451
7Septo-optic dysplasia (HP:0100842)5.49264801
8Severe visual impairment (HP:0001141)5.45839955
9Decreased central vision (HP:0007663)5.16199851
10Cone-rod dystrophy (HP:0000548)4.81644074
11Pendular nystagmus (HP:0012043)4.75531753
12Chorioretinal atrophy (HP:0000533)4.74605387
13Dyschromatopsia (HP:0007641)4.65136036
14Absent rod-and cone-mediated responses on ERG (HP:0007688)4.60103833
15Attenuation of retinal blood vessels (HP:0007843)4.28617134
16Increased corneal curvature (HP:0100692)4.13074117
17Keratoconus (HP:0000563)4.13074117
18Pigmentary retinal degeneration (HP:0001146)4.03518906
19Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)3.90373938
20Facial hemangioma (HP:0000329)3.76142337
21Abolished electroretinogram (ERG) (HP:0000550)3.67284728
22Male infertility (HP:0003251)3.52299930
23Aplasia/Hypoplasia of the fovea (HP:0008060)3.47646915
24Hypoplasia of the fovea (HP:0007750)3.47646915
25Oligodactyly (hands) (HP:0001180)3.42058387
26Hypophosphatemic rickets (HP:0004912)3.40792951
27Absent septum pellucidum (HP:0001331)3.34804449
28Abnormality of the fovea (HP:0000493)3.31320475
29Photophobia (HP:0000613)3.26360098
30Posterior subcapsular cataract (HP:0007787)3.24391475
31Impulsivity (HP:0100710)3.22063842
32Hyperglycinemia (HP:0002154)3.18965532
33Osteomalacia (HP:0002749)3.14080487
34Fair hair (HP:0002286)3.12004653
35Febrile seizures (HP:0002373)3.11485260
36Aplasia/Hypoplasia of the tibia (HP:0005772)3.10730701
37Type II diabetes mellitus (HP:0005978)3.09236217
38Gonadotropin excess (HP:0000837)3.04836179
39Gait imbalance (HP:0002141)3.04677275
40Cholecystitis (HP:0001082)3.02452825
41Abnormal gallbladder physiology (HP:0012438)3.02452825
42Congenital primary aphakia (HP:0007707)3.02418868
43Median cleft lip (HP:0000161)3.02223227
44Epileptic encephalopathy (HP:0200134)2.98194560
45Capillary hemangiomas (HP:0005306)2.85092287
46Chromosomal breakage induced by crosslinking agents (HP:0003221)2.83057444
47Macular degeneration (HP:0000608)2.82756069
48Abnormality of the septum pellucidum (HP:0007375)2.77318720
49Abnormal ciliary motility (HP:0012262)2.76080593
50Bile duct proliferation (HP:0001408)2.74541139
51Abnormal biliary tract physiology (HP:0012439)2.74541139
52Gaze-evoked nystagmus (HP:0000640)2.69567657
53Oral leukoplakia (HP:0002745)2.67421687
54Short tibia (HP:0005736)2.66188779
55Anterior segment dysgenesis (HP:0007700)2.65895705
56Nephrogenic diabetes insipidus (HP:0009806)2.63916513
57Poor coordination (HP:0002370)2.63817367
58Medial flaring of the eyebrow (HP:0010747)2.60081650
59Oligodactyly (HP:0012165)2.57454448
60Azoospermia (HP:0000027)2.57119399
61Optic nerve hypoplasia (HP:0000609)2.55024599
62Congenital sensorineural hearing impairment (HP:0008527)2.54274687
63Papillary thyroid carcinoma (HP:0002895)2.53297729
64Infertility (HP:0000789)2.52589737
65Conjunctival telangiectasia (HP:0000524)2.50125199
66Retinitis pigmentosa (HP:0000510)2.48319596
67Subcapsular cataract (HP:0000523)2.46685299
68Unsteady gait (HP:0002317)2.43417284
69Aplasia/Hypoplasia affecting the fundus (HP:0008057)2.42522648
70Intrahepatic cholestasis (HP:0001406)2.40247916
71Malnutrition (HP:0004395)2.38450888
72Constricted visual fields (HP:0001133)2.37403688
73Dynein arm defect of respiratory motile cilia (HP:0012255)2.35820181
74Absent/shortened dynein arms (HP:0200106)2.35820181
75Growth hormone deficiency (HP:0000824)2.34693196
76Aplasia/Hypoplasia of the macula (HP:0008059)2.33518983
77Mutism (HP:0002300)2.31589125
78Lip pit (HP:0100267)2.26074806
79Abnormality of abdominal situs (HP:0011620)2.22811169
80Abdominal situs inversus (HP:0003363)2.22811169
81Colon cancer (HP:0003003)2.22491151
82Abnormal respiratory motile cilium physiology (HP:0012261)2.21145774
83Prostate neoplasm (HP:0100787)2.20130928
84Thyroid carcinoma (HP:0002890)2.19958295
85Metaphyseal irregularity (HP:0003025)2.19318733
86Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.18934811
87Aplasia/Hypoplasia affecting the retina (HP:0008061)2.13273769
88Thyroid-stimulating hormone excess (HP:0002925)2.13240476
89Choroideremia (HP:0001139)2.11439947
90Vaginal atresia (HP:0000148)2.10411382
91Hemiplegia (HP:0002301)2.09656492
92Genital tract atresia (HP:0001827)2.07198995
93Methylmalonic acidemia (HP:0002912)2.07068562
94Abnormal auditory evoked potentials (HP:0006958)2.06469780
95Abnormality of chromosome stability (HP:0003220)2.06404293
96Aplasia/Hypoplasia of the uvula (HP:0010293)2.03479715
97Proximal tubulopathy (HP:0000114)2.01983076
98Generalized hypopigmentation of hair (HP:0011358)2.01932414
99Neoplasm of the oral cavity (HP:0100649)2.01039446
100Congenital stationary night blindness (HP:0007642)11.1272915
101Stomach cancer (HP:0012126)1.99987632
102Abnormality of the vasculature of the conjunctiva (HP:0008054)1.98656623
103Chorioretinal coloboma (HP:0000567)1.97755383
104Abnormal spermatogenesis (HP:0008669)1.95377519
105Bicornuate uterus (HP:0000813)1.95008992
1063-Methylglutaconic aciduria (HP:0003535)1.94021153
107Rhinitis (HP:0012384)1.93903319
108Aplastic anemia (HP:0001915)1.93390842
109Aplasia/Hypoplasia of the lens (HP:0008063)1.92008600
110Medulloblastoma (HP:0002885)1.88699574
111Ileus (HP:0002595)1.87284789
112Myokymia (HP:0002411)1.87238739
113Abnormality of aromatic amino acid family metabolism (HP:0004338)1.86699776
114Muscle stiffness (HP:0003552)1.85318430
115Meckel diverticulum (HP:0002245)1.84535432
116Progressive cerebellar ataxia (HP:0002073)1.84248380
117Wrist flexion contracture (HP:0001239)1.82638882
118Acute lymphatic leukemia (HP:0006721)1.82567987
119Postural instability (HP:0002172)1.82199730
120Abnormality of B cell number (HP:0010975)1.80926381
121Ependymoma (HP:0002888)1.79755729
122Nephronophthisis (HP:0000090)1.79192922
123Abnormality of the ileum (HP:0001549)1.77475002
124Abnormality of the sella turcica (HP:0002679)1.75636368
125Horizontal nystagmus (HP:0000666)1.75487439
126Visual hallucinations (HP:0002367)1.75206960
127Tubulointerstitial nephritis (HP:0001970)1.74768028
128Aplasia/Hypoplasia of the tongue (HP:0010295)1.71285655
129Abnormality of the parathyroid morphology (HP:0011766)1.68078472
130Abnormality of the fingertips (HP:0001211)1.67678597
131Dysdiadochokinesis (HP:0002075)1.67421967
132Astigmatism (HP:0000483)1.65795267
133Left ventricular hypertrophy (HP:0001712)1.65381994
134Adrenal hypoplasia (HP:0000835)1.64471880
135Cortical dysplasia (HP:0002539)1.61601310
136True hermaphroditism (HP:0010459)1.61072868
137Leiomyosarcoma (HP:0100243)1.59922961
138Uterine leiomyosarcoma (HP:0002891)1.59922961
139Torticollis (HP:0000473)1.58319127
140Albinism (HP:0001022)1.57997043
141Primary adrenal insufficiency (HP:0008207)1.56359502
142Insulin-resistant diabetes mellitus (HP:0000831)1.56271246
143Fetal akinesia sequence (HP:0001989)1.54622844
144Vitreoretinal degeneration (HP:0000655)1.54619115
145Molar tooth sign on MRI (HP:0002419)1.54152960
146Abnormality of midbrain morphology (HP:0002418)1.54152960
147Pancreatic fibrosis (HP:0100732)1.53031637
148Abnormality of the labia minora (HP:0012880)1.51051261
149Primary amenorrhea (HP:0000786)1.50914984
150Chromsome breakage (HP:0040012)1.49594445
151Decreased electroretinogram (ERG) amplitude (HP:0000654)1.47311624
152Abnormality of the astrocytes (HP:0100707)1.47217875
153Astrocytoma (HP:0009592)1.47217875
154Hirsutism (HP:0001007)1.47181948
155Pancreatic cysts (HP:0001737)1.46706108
156Arterial tortuosity (HP:0005116)1.45510639
157Broad foot (HP:0001769)1.43606305
158Atonic seizures (HP:0010819)1.39841036
159Flat capital femoral epiphysis (HP:0003370)1.39763697

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA34.91329298
2NEK13.95558620
3FRK3.87063309
4PAK63.83773537
5LATS13.76077371
6LATS23.26882285
7MAP3K63.14055299
8TAOK33.08946708
9KSR22.82657552
10STK38L2.68995587
11NEK62.51027868
12PIK3CG2.30539743
13MOS2.29304758
14BMPR22.12757828
15ZAK2.03157043
16CDK82.02639137
17ERBB41.95488349
18MAP3K91.89602196
19RAF11.87887751
20BRAF1.87190075
21TRIM281.85393393
22PINK11.84414843
23STK381.81634408
24MAP4K21.76216176
25MET1.74002501
26EIF2AK31.71873568
27TTK1.70706866
28PBK1.68244654
29MAP2K71.67142918
30PLK41.59033760
31PRKD31.57510576
32EEF2K1.56346051
33MAP3K131.50487100
34PNCK1.49982086
35MAP3K41.42974526
36TNIK1.40474887
37BMPR1B1.35985348
38TNK21.35452574
39TAOK11.35385089
40KDR1.34781365
41MARK31.34750572
42CDC71.32410085
43CSNK1G31.31563327
44PRKCI1.30454456
45STK241.30053100
46GRK11.28724552
47CHEK21.26118921
48KSR11.26065350
49PRKD21.22574596
50PRPF4B1.22292616
51CDK91.20875605
52PKN11.19500086
53WNK31.13324336
54MUSK1.10228794
55OXSR11.06017433
56PIM11.05055078
57DYRK21.02950052
58CDK31.00835256
59PRKG21.00563303
60VRK11.00014257
61VRK20.99869219
62SGK4940.99118856
63SGK2230.99118856
64GRK50.98570578
65PHKG10.98062221
66PHKG20.98062221
67ARAF0.95870939
68MAPK130.94453682
69CDK190.94322036
70TIE10.93534645
71DYRK1A0.93493874
72CDK70.91600265
73TEC0.88019626
74FLT30.86748895
75CSNK1A1L0.85250024
76ADRBK20.83432704
77STK390.81332431
78RPS6KB20.80326343
79STK30.80283887
80NEK90.79196740
81PRKAA10.76746366
82SGK20.76671909
83MARK20.76524482
84CSF1R0.75001304
85DMPK0.74486572
86PLK10.73096333
87NEK20.72769872
88CCNB10.72143305
89AKT30.70377956
90MAP3K120.69298371
91PRKAA20.68876339
92MAP2K40.68248195
93MELK0.67777760
94NTRK30.62830720
95RPS6KA40.60990689
96ACVR1B0.60261224
97MAP3K10.55199853
98NTRK20.53437579
99PLK30.52563718
100MAPK100.52451663
101MAPKAPK50.50735927
102MINK10.50720462
103AURKB0.48561577
104MAP3K70.48434209
105PRKACA0.47675178
106PRKACB0.47642980
107PAK30.47279015
108BRSK20.47113146
109SRPK10.46539932
110MARK10.45536158
111AURKA0.45167207
112TAOK20.44680333
113MST40.44428300
114ATM0.44331733
115RET0.42864533
116NUAK10.42164836
117CAMK2A0.40644408
118MAPKAPK30.40301933
119CDK150.40233950
120CDK10.38991609
121SGK30.38418415
122DYRK1B0.37380868
123WEE10.37350757
124GSK3B0.37344126
125CSNK1A10.37095650
126CAMK10.36228796
127MAPK140.36043269
128RPS6KA30.35823727
129CDK180.35442840
130INSRR0.34998011
131KIT0.34439277
132BCKDK0.34427454
133RPS6KA50.33572086
134GSK3A0.33456593
135EIF2AK20.33120302
136CDK11A0.32358226
137HIPK20.32292763
138CDK50.32170105
139CDK140.32122895
140CSNK1G10.32036230
141CSNK1G20.31455104
142LMTK20.31167569
143PLK20.31133694
144ERBB20.30771687
145MAP3K50.30629888
146PRKG10.30468374
147CHEK10.29682642
148MAPK90.29393441
149SGK10.28370026
150AKT10.27476070
151CSNK1D0.26879184
152ATR0.26692005
153CSNK1E0.25639902
154CDK20.24186386
155BRSK10.22446137

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047445.49174759
2Circadian rhythm_Homo sapiens_hsa047103.71805703
3Synaptic vesicle cycle_Homo sapiens_hsa047213.60454931
4* Nicotine addiction_Homo sapiens_hsa050333.10208850
5Caffeine metabolism_Homo sapiens_hsa002323.03712725
6Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.74277010
7Mismatch repair_Homo sapiens_hsa034302.63267902
8* GABAergic synapse_Homo sapiens_hsa047272.62151901
9* Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.36025945
10Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.26441017
11Ovarian steroidogenesis_Homo sapiens_hsa049132.02711208
12Circadian entrainment_Homo sapiens_hsa047131.89468346
13Cholinergic synapse_Homo sapiens_hsa047251.85365716
14Vitamin digestion and absorption_Homo sapiens_hsa049771.78739711
15* Morphine addiction_Homo sapiens_hsa050321.76775719
16Nucleotide excision repair_Homo sapiens_hsa034201.73123946
17RNA degradation_Homo sapiens_hsa030181.71935566
18DNA replication_Homo sapiens_hsa030301.67203649
19Serotonergic synapse_Homo sapiens_hsa047261.64658078
20Oxytocin signaling pathway_Homo sapiens_hsa049211.60517127
21Cell cycle_Homo sapiens_hsa041101.60025417
22Insulin secretion_Homo sapiens_hsa049111.57795728
23Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.52392187
24Glutamatergic synapse_Homo sapiens_hsa047241.50161542
25Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.46495015
26Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.45337715
27Oocyte meiosis_Homo sapiens_hsa041141.45139155
28Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.42409731
29Basal transcription factors_Homo sapiens_hsa030221.39138147
30Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.37660035
31Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.33971183
32Aldosterone synthesis and secretion_Homo sapiens_hsa049251.32999832
33Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.32702115
34Butanoate metabolism_Homo sapiens_hsa006501.32075286
35Fanconi anemia pathway_Homo sapiens_hsa034601.30110000
36Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.26271823
37mTOR signaling pathway_Homo sapiens_hsa041501.24773564
38GnRH signaling pathway_Homo sapiens_hsa049121.23312980
39Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.21755789
40Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.19572603
41Asthma_Homo sapiens_hsa053101.16932971
42Dilated cardiomyopathy_Homo sapiens_hsa054141.14077290
43Dopaminergic synapse_Homo sapiens_hsa047281.12952364
44Fatty acid elongation_Homo sapiens_hsa000621.11428107
45Salivary secretion_Homo sapiens_hsa049701.11382512
46Collecting duct acid secretion_Homo sapiens_hsa049661.08860496
47Olfactory transduction_Homo sapiens_hsa047401.07793373
48Pancreatic cancer_Homo sapiens_hsa052121.04660881
49Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.04288146
50Propanoate metabolism_Homo sapiens_hsa006401.03390239
51Carbohydrate digestion and absorption_Homo sapiens_hsa049731.01314567
52Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.98588516
53Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.98000080
54Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.97186864
55Huntingtons disease_Homo sapiens_hsa050160.96640957
56Renal cell carcinoma_Homo sapiens_hsa052110.94808012
57Colorectal cancer_Homo sapiens_hsa052100.94347466
58Ether lipid metabolism_Homo sapiens_hsa005650.93327718
59Purine metabolism_Homo sapiens_hsa002300.92384675
60p53 signaling pathway_Homo sapiens_hsa041150.91208477
61Non-homologous end-joining_Homo sapiens_hsa034500.91159200
62Chemical carcinogenesis_Homo sapiens_hsa052040.89188578
63Cardiac muscle contraction_Homo sapiens_hsa042600.89161482
64Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.88910568
65cAMP signaling pathway_Homo sapiens_hsa040240.87995667
66alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.87845259
67Histidine metabolism_Homo sapiens_hsa003400.87659775
68Folate biosynthesis_Homo sapiens_hsa007900.86879392
69Biosynthesis of amino acids_Homo sapiens_hsa012300.86571441
70Choline metabolism in cancer_Homo sapiens_hsa052310.85969817
71cGMP-PKG signaling pathway_Homo sapiens_hsa040220.83063019
72SNARE interactions in vesicular transport_Homo sapiens_hsa041300.81514834
73Thyroid hormone signaling pathway_Homo sapiens_hsa049190.80840144
74Renin secretion_Homo sapiens_hsa049240.80511309
75Tryptophan metabolism_Homo sapiens_hsa003800.80064311
76Steroid hormone biosynthesis_Homo sapiens_hsa001400.79081044
77Linoleic acid metabolism_Homo sapiens_hsa005910.78335301
78Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.75399329
79Arachidonic acid metabolism_Homo sapiens_hsa005900.74683887
80Long-term depression_Homo sapiens_hsa047300.74048490
81Endometrial cancer_Homo sapiens_hsa052130.73972889
82Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.73190307
83Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.72683564
84Base excision repair_Homo sapiens_hsa034100.71834562
85Glycerolipid metabolism_Homo sapiens_hsa005610.68103806
86Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.66850009
87Vitamin B6 metabolism_Homo sapiens_hsa007500.65464384
88Vascular smooth muscle contraction_Homo sapiens_hsa042700.64603260
89MAPK signaling pathway_Homo sapiens_hsa040100.64367920
90Parkinsons disease_Homo sapiens_hsa050120.63715516
91Intestinal immune network for IgA production_Homo sapiens_hsa046720.63544211
92beta-Alanine metabolism_Homo sapiens_hsa004100.61624828
93Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.60213281
94Calcium signaling pathway_Homo sapiens_hsa040200.59617218
95Dorso-ventral axis formation_Homo sapiens_hsa043200.57790589
96Retinol metabolism_Homo sapiens_hsa008300.56341136
97Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.56306329
98Glycerophospholipid metabolism_Homo sapiens_hsa005640.56203934
99Longevity regulating pathway - mammal_Homo sapiens_hsa042110.55651703
100Platelet activation_Homo sapiens_hsa046110.53589521
101Maturity onset diabetes of the young_Homo sapiens_hsa049500.53527086
102Prolactin signaling pathway_Homo sapiens_hsa049170.52253127
103* Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.48701677
104Inositol phosphate metabolism_Homo sapiens_hsa005620.47514683
105ABC transporters_Homo sapiens_hsa020100.47271712
106ErbB signaling pathway_Homo sapiens_hsa040120.47028227
107Taste transduction_Homo sapiens_hsa047420.46684344
108Hippo signaling pathway_Homo sapiens_hsa043900.46662828
109Allograft rejection_Homo sapiens_hsa053300.46634010
110Cyanoamino acid metabolism_Homo sapiens_hsa004600.45978281
111Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.45849980
112Ras signaling pathway_Homo sapiens_hsa040140.45151737
113Fat digestion and absorption_Homo sapiens_hsa049750.44565869
114Type II diabetes mellitus_Homo sapiens_hsa049300.44196479
115Homologous recombination_Homo sapiens_hsa034400.43047533
116Phosphatidylinositol signaling system_Homo sapiens_hsa040700.42977364
117Gap junction_Homo sapiens_hsa045400.42787258
118Cysteine and methionine metabolism_Homo sapiens_hsa002700.42700284
119Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.42391324
120African trypanosomiasis_Homo sapiens_hsa051430.41508180
121Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.41503465
122Autoimmune thyroid disease_Homo sapiens_hsa053200.40865932
123Central carbon metabolism in cancer_Homo sapiens_hsa052300.39262106
124Vibrio cholerae infection_Homo sapiens_hsa051100.39241199
125Oxidative phosphorylation_Homo sapiens_hsa001900.38686244
126Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.37516036
127Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.36866653
128Fructose and mannose metabolism_Homo sapiens_hsa000510.36072933
129Phospholipase D signaling pathway_Homo sapiens_hsa040720.35697469
130Metabolic pathways_Homo sapiens_hsa011000.35628905
131Mineral absorption_Homo sapiens_hsa049780.35330557
132VEGF signaling pathway_Homo sapiens_hsa043700.34539387
133Melanoma_Homo sapiens_hsa052180.33901907
134Gastric acid secretion_Homo sapiens_hsa049710.32798102
135RNA polymerase_Homo sapiens_hsa030200.32605384
136Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.32249969
137Long-term potentiation_Homo sapiens_hsa047200.31626966
138Bile secretion_Homo sapiens_hsa049760.29616559
139RNA transport_Homo sapiens_hsa030130.29430551
140Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.29002547
141mRNA surveillance pathway_Homo sapiens_hsa030150.28951865
142AMPK signaling pathway_Homo sapiens_hsa041520.28655936
143Glutathione metabolism_Homo sapiens_hsa004800.28533583
144Arginine and proline metabolism_Homo sapiens_hsa003300.28298864
145Hematopoietic cell lineage_Homo sapiens_hsa046400.25064076
146Graft-versus-host disease_Homo sapiens_hsa053320.24596125
147Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.24485163
148Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.23157099
149Regulation of autophagy_Homo sapiens_hsa041400.21937541
150Nitrogen metabolism_Homo sapiens_hsa009100.20971819

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