

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | pyrimidine nucleoside monophosphate metabolic process (GO:0009129) | 9.57553956 |
| 2 | diterpenoid biosynthetic process (GO:0016102) | 8.39316059 |
| 3 | CTP metabolic process (GO:0046036) | 7.62108789 |
| 4 | CTP biosynthetic process (GO:0006241) | 7.62108789 |
| 5 | keratinocyte development (GO:0003334) | 7.36774109 |
| 6 | pentose-phosphate shunt (GO:0006098) | 7.27203358 |
| 7 | pentose metabolic process (GO:0019321) | 7.22196674 |
| 8 | terpenoid biosynthetic process (GO:0016114) | 7.11305041 |
| 9 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 7.05304100 |
| 10 | regulation of glycogen (starch) synthase activity (GO:2000465) | 6.91523327 |
| 11 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 6.71731389 |
| 12 | NADPH regeneration (GO:0006740) | 6.63083514 |
| 13 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 5.99004396 |
| 14 | activation of NF-kappaB-inducing kinase activity (GO:0007250) | 5.91243532 |
| 15 | regulation of activation of Janus kinase activity (GO:0010533) | 5.85831189 |
| 16 | glucose catabolic process (GO:0006007) | 5.61541383 |
| 17 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 5.51654927 |
| 18 | purine nucleotide salvage (GO:0032261) | 5.36267208 |
| 19 | pyrimidine ribonucleoside biosynthetic process (GO:0046132) | 5.25193346 |
| 20 | negative regulation of keratinocyte proliferation (GO:0010839) | 5.24115256 |
| 21 | cellular metabolic compound salvage (GO:0043094) | 5.23028638 |
| 22 | translational termination (GO:0006415) | 5.15710254 |
| 23 | viral transcription (GO:0019083) | 5.15373284 |
| 24 | pyrimidine ribonucleotide biosynthetic process (GO:0009220) | 5.11597672 |
| 25 | peptidyl-lysine dimethylation (GO:0018027) | 4.96886229 |
| 26 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.94092572 |
| 27 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.94092572 |
| 28 | pyrimidine ribonucleotide metabolic process (GO:0009218) | 4.72135975 |
| 29 | positive regulation of NIK/NF-kappaB signaling (GO:1901224) | 4.64620701 |
| 30 | translational elongation (GO:0006414) | 4.64127007 |
| 31 | interleukin-6-mediated signaling pathway (GO:0070102) | 4.51295521 |
| 32 | negative regulation of JAK-STAT cascade (GO:0046426) | 4.41481865 |
| 33 | peptidyl-cysteine modification (GO:0018198) | 4.27109400 |
| 34 | retinal metabolic process (GO:0042574) | 4.22151238 |
| 35 | response to folic acid (GO:0051593) | 4.16529598 |
| 36 | pyrimidine nucleotide biosynthetic process (GO:0006221) | 4.13403529 |
| 37 | neutrophil mediated immunity (GO:0002446) | 4.10777000 |
| 38 | centrosome duplication (GO:0051298) | 4.09604019 |
| 39 | DNA ligation (GO:0006266) | 4.06456878 |
| 40 | cellular protein complex disassembly (GO:0043624) | 4.06412355 |
| 41 | establishment of skin barrier (GO:0061436) | 3.97638558 |
| 42 | regulation of NIK/NF-kappaB signaling (GO:1901222) | 3.89677087 |
| 43 | response to nitric oxide (GO:0071731) | 3.87570031 |
| 44 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.81540303 |
| 45 | pyrimidine ribonucleoside metabolic process (GO:0046131) | 3.80949838 |
| 46 | DNA synthesis involved in DNA repair (GO:0000731) | 3.73326382 |
| 47 | cotranslational protein targeting to membrane (GO:0006613) | 3.73290241 |
| 48 | catecholamine transport (GO:0051937) | 3.73059705 |
| 49 | pyrimidine nucleoside biosynthetic process (GO:0046134) | 3.68936426 |
| 50 | protein-chromophore linkage (GO:0018298) | 3.67964812 |
| 51 | protein targeting to ER (GO:0045047) | 3.65716486 |
| 52 | protein complex disassembly (GO:0043241) | 3.62445935 |
| 53 | negative regulation of stem cell proliferation (GO:2000647) | 3.60418625 |
| 54 | viral life cycle (GO:0019058) | 3.51085711 |
| 55 | positive regulation of epidermal cell differentiation (GO:0045606) | 3.49235452 |
| 56 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.49060984 |
| 57 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.43512267 |
| 58 | NADP metabolic process (GO:0006739) | 3.43174440 |
| 59 | macromolecular complex disassembly (GO:0032984) | 3.40571794 |
| 60 | protein localization to endoplasmic reticulum (GO:0070972) | 3.36524503 |
| 61 | grooming behavior (GO:0007625) | 3.28941035 |
| 62 | DNA dealkylation (GO:0035510) | 3.27733774 |
| 63 | negative regulation of interleukin-8 production (GO:0032717) | 3.21507337 |
| 64 | extrinsic apoptotic signaling pathway via death domain receptors (GO:0008625) | 3.13501222 |
| 65 | pyrimidine-containing compound biosynthetic process (GO:0072528) | 3.11590014 |
| 66 | ribosomal small subunit assembly (GO:0000028) | 3.06507915 |
| 67 | myeloid leukocyte mediated immunity (GO:0002444) | 3.05124860 |
| 68 | regulation of water loss via skin (GO:0033561) | 3.03536556 |
| 69 | AMP metabolic process (GO:0046033) | 3.02937606 |
| 70 | tRNA modification (GO:0006400) | 3.00786704 |
| 71 | positive regulation of branching involved in ureteric bud morphogenesis (GO:0090190) | 2.94118152 |
| 72 | neutrophil activation involved in immune response (GO:0002283) | 2.92320544 |
| 73 | pyrimidine nucleotide metabolic process (GO:0006220) | 2.92060192 |
| 74 | translesion synthesis (GO:0019985) | 2.91219502 |
| 75 | isoprenoid biosynthetic process (GO:0008299) | 2.89705553 |
| 76 | purine nucleobase biosynthetic process (GO:0009113) | 2.87684251 |
| 77 | monocyte chemotaxis (GO:0002548) | 2.85071597 |
| 78 | daunorubicin metabolic process (GO:0044597) | 2.82262484 |
| 79 | polyketide metabolic process (GO:0030638) | 2.82262484 |
| 80 | doxorubicin metabolic process (GO:0044598) | 2.82262484 |
| 81 | heparin metabolic process (GO:0030202) | 2.81169830 |
| 82 | heparin biosynthetic process (GO:0030210) | 2.81169830 |
| 83 | retinoic acid metabolic process (GO:0042573) | 2.76860036 |
| 84 | organ or tissue specific immune response (GO:0002251) | 2.75939226 |
| 85 | regulation of hypersensitivity (GO:0002883) | 2.74206794 |
| 86 | translational initiation (GO:0006413) | 2.70139296 |
| 87 | peptidyl-lysine trimethylation (GO:0018023) | 2.66532275 |
| 88 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 2.65406911 |
| 89 | cytokinetic process (GO:0032506) | 2.65406184 |
| 90 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.60604287 |
| 91 | aminoglycoside antibiotic metabolic process (GO:0030647) | 2.59393827 |
| 92 | pyrimidine nucleoside salvage (GO:0043097) | 13.3286157 |
| 93 | pyrimidine-containing compound salvage (GO:0008655) | 13.3286157 |
| 94 | nucleotide salvage (GO:0043173) | 12.8095086 |
| 95 | nucleoside salvage (GO:0043174) | 11.8227193 |
| 96 | pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) | 11.7943940 |
| 97 | UMP biosynthetic process (GO:0006222) | 11.7943940 |
| 98 | pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174) | 11.7943940 |
| 99 | UMP metabolic process (GO:0046049) | 11.7943940 |
| 100 | pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130) | 10.0445648 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 4.04757237 |
| 2 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 3.95255888 |
| 3 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.87956114 |
| 4 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 3.75976433 |
| 5 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.64714947 |
| 6 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.80127652 |
| 7 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.58276636 |
| 8 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.55658641 |
| 9 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.53624820 |
| 10 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 2.51841911 |
| 11 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.41075803 |
| 12 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.37098908 |
| 13 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.20170861 |
| 14 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 2.14636314 |
| 15 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.10495530 |
| 16 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.10008769 |
| 17 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.09559569 |
| 18 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.06286917 |
| 19 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.97940322 |
| 20 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.95766446 |
| 21 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.95537399 |
| 22 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.94608256 |
| 23 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.94117584 |
| 24 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.93772065 |
| 25 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.91374203 |
| 26 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.90513969 |
| 27 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.90513969 |
| 28 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.87230338 |
| 29 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.85286518 |
| 30 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.83625400 |
| 31 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.82034977 |
| 32 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.81151407 |
| 33 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.80279083 |
| 34 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.73462015 |
| 35 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.70550082 |
| 36 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.67747989 |
| 37 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.58957064 |
| 38 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.56403746 |
| 39 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.54833235 |
| 40 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.49939340 |
| 41 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.49651280 |
| 42 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.48286998 |
| 43 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.44634024 |
| 44 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.44634024 |
| 45 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.44634024 |
| 46 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.44141703 |
| 47 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.43536730 |
| 48 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.40744925 |
| 49 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.37861999 |
| 50 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.34642276 |
| 51 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.29344258 |
| 52 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.26091001 |
| 53 | ERA_21632823_ChIP-Seq_H3396_Human | 1.20177065 |
| 54 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.17925755 |
| 55 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.14497615 |
| 56 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.13017036 |
| 57 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.11925605 |
| 58 | JUN_21703547_ChIP-Seq_K562_Human | 1.11378084 |
| 59 | MYC_19915707_ChIP-ChIP_AK7_Human | 1.05942251 |
| 60 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.04889295 |
| 61 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.02495587 |
| 62 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.02152278 |
| 63 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.01378433 |
| 64 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.01043927 |
| 65 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.00575071 |
| 66 | NCOR_22424771_ChIP-Seq_293T_Human | 1.00078503 |
| 67 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.98653012 |
| 68 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.96953440 |
| 69 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.96365854 |
| 70 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.96026606 |
| 71 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.95703493 |
| 72 | FUS_26573619_Chip-Seq_HEK293_Human | 0.95115348 |
| 73 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.94813998 |
| 74 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.94284918 |
| 75 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.93678882 |
| 76 | P300_19829295_ChIP-Seq_ESCs_Human | 0.92841374 |
| 77 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.92775368 |
| 78 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.92608964 |
| 79 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.90293712 |
| 80 | P68_20966046_ChIP-Seq_HELA_Human | 0.89401829 |
| 81 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.88849908 |
| 82 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.88133846 |
| 83 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.87735076 |
| 84 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.86059829 |
| 85 | NANOG_18692474_ChIP-Seq_MEFs_Mouse | 0.85465124 |
| 86 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.84237597 |
| 87 | E2F7_22180533_ChIP-Seq_HELA_Human | 0.83543822 |
| 88 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.82955863 |
| 89 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 0.82720571 |
| 90 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.82299008 |
| 91 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.82221572 |
| 92 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.82208925 |
| 93 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.81852771 |
| 94 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.81852771 |
| 95 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.81710555 |
| 96 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.81643509 |
| 97 | P63_20808887_ChIP-Seq_KERATINOCYTES_Human | 0.81573525 |
| 98 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.81513531 |
| 99 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.80350570 |
| 100 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.80320523 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003880_abnormal_central_pattern | 5.08904244 |
| 2 | MP0002163_abnormal_gland_morphology | 4.58719418 |
| 3 | MP0006292_abnormal_olfactory_placode | 4.51747926 |
| 4 | MP0002234_abnormal_pharynx_morphology | 3.53477759 |
| 5 | MP0001873_stomach_inflammation | 3.41188247 |
| 6 | MP0003724_increased_susceptibility_to | 3.17415335 |
| 7 | MP0001346_abnormal_lacrimal_gland | 3.04721162 |
| 8 | MP0003646_muscle_fatigue | 3.01933327 |
| 9 | MP0001348_abnormal_lacrimal_gland | 2.98398080 |
| 10 | MP0006082_CNS_inflammation | 2.89966321 |
| 11 | MP0000538_abnormal_urinary_bladder | 2.58152016 |
| 12 | MP0006276_abnormal_autonomic_nervous | 2.57730063 |
| 13 | MP0005379_endocrine/exocrine_gland_phen | 2.54097629 |
| 14 | MP0008875_abnormal_xenobiotic_pharmacok | 2.40715858 |
| 15 | MP0005360_urolithiasis | 2.36945392 |
| 16 | MP0009379_abnormal_foot_pigmentation | 2.34730669 |
| 17 | MP0005423_abnormal_somatic_nervous | 2.22741434 |
| 18 | MP0003787_abnormal_imprinting | 2.15998345 |
| 19 | MP0001293_anophthalmia | 2.06856742 |
| 20 | MP0005310_abnormal_salivary_gland | 2.01612267 |
| 21 | MP0002822_catalepsy | 1.88603624 |
| 22 | MP0001986_abnormal_taste_sensitivity | 1.72767340 |
| 23 | MP0003279_aneurysm | 1.70747312 |
| 24 | MP0001663_abnormal_digestive_system | 1.66686817 |
| 25 | MP0008789_abnormal_olfactory_epithelium | 1.62879176 |
| 26 | MP0008872_abnormal_physiological_respon | 1.59840366 |
| 27 | MP0001664_abnormal_digestion | 1.53607645 |
| 28 | MP0003119_abnormal_digestive_system | 1.52368531 |
| 29 | MP0003123_paternal_imprinting | 1.46710507 |
| 30 | MP0005167_abnormal_blood-brain_barrier | 1.40599083 |
| 31 | MP0000383_abnormal_hair_follicle | 1.36272516 |
| 32 | MP0001756_abnormal_urination | 1.36182670 |
| 33 | MP0002876_abnormal_thyroid_physiology | 1.31610994 |
| 34 | MP0005499_abnormal_olfactory_system | 1.28977796 |
| 35 | MP0005394_taste/olfaction_phenotype | 1.28977796 |
| 36 | MP0005381_digestive/alimentary_phenotyp | 1.24824841 |
| 37 | MP0002932_abnormal_joint_morphology | 1.22958426 |
| 38 | MP0010155_abnormal_intestine_physiology | 1.19014077 |
| 39 | MP0010329_abnormal_lipoprotein_level | 1.12692215 |
| 40 | MP0002933_joint_inflammation | 1.11358496 |
| 41 | MP0010386_abnormal_urinary_bladder | 1.10525184 |
| 42 | MP0002095_abnormal_skin_pigmentation | 1.08939628 |
| 43 | MP0008995_early_reproductive_senescence | 1.08630008 |
| 44 | MP0002233_abnormal_nose_morphology | 1.07474553 |
| 45 | MP0003866_abnormal_defecation | 1.02954316 |
| 46 | MP0001529_abnormal_vocalization | 1.02270092 |
| 47 | MP0004885_abnormal_endolymph | 1.02054563 |
| 48 | MP0000049_abnormal_middle_ear | 1.01347997 |
| 49 | MP0003878_abnormal_ear_physiology | 1.01077303 |
| 50 | MP0005377_hearing/vestibular/ear_phenot | 1.01077303 |
| 51 | MP0000631_abnormal_neuroendocrine_gland | 0.98545810 |
| 52 | MP0005000_abnormal_immune_tolerance | 0.98189092 |
| 53 | MP0002837_dystrophic_cardiac_calcinosis | 0.92342361 |
| 54 | MP0003011_delayed_dark_adaptation | 0.92122823 |
| 55 | MP0000613_abnormal_salivary_gland | 0.91584712 |
| 56 | MP0005503_abnormal_tendon_morphology | 0.91020131 |
| 57 | MP0002653_abnormal_ependyma_morphology | 0.90605739 |
| 58 | MP0000569_abnormal_digit_pigmentation | 0.89435476 |
| 59 | MP0000955_abnormal_spinal_cord | 0.87576142 |
| 60 | MP0000778_abnormal_nervous_system | 0.85057073 |
| 61 | MP0001286_abnormal_eye_development | 0.84740087 |
| 62 | MP0008775_abnormal_heart_ventricle | 0.83022802 |
| 63 | MP0005332_abnormal_amino_acid | 0.82505629 |
| 64 | MP0001905_abnormal_dopamine_level | 0.82283174 |
| 65 | MP0009785_altered_susceptibility_to | 0.77799719 |
| 66 | MP0003121_genomic_imprinting | 0.76250282 |
| 67 | MP0001944_abnormal_pancreas_morphology | 0.75436397 |
| 68 | MP0004145_abnormal_muscle_electrophysio | 0.75277647 |
| 69 | MP0002272_abnormal_nervous_system | 0.74777344 |
| 70 | MP0003136_yellow_coat_color | 0.73971993 |
| 71 | MP0001485_abnormal_pinna_reflex | 0.73885392 |
| 72 | MP0002752_abnormal_somatic_nervous | 0.73026040 |
| 73 | MP0009745_abnormal_behavioral_response | 0.72870348 |
| 74 | MP0000467_abnormal_esophagus_morphology | 0.70578761 |
| 75 | MP0003943_abnormal_hepatobiliary_system | 0.69747134 |
| 76 | MP0000372_irregular_coat_pigmentation | 0.69544922 |
| 77 | MP0005551_abnormal_eye_electrophysiolog | 0.69199374 |
| 78 | MP0002092_abnormal_eye_morphology | 0.67861482 |
| 79 | MP0000470_abnormal_stomach_morphology | 0.67550304 |
| 80 | MP0002160_abnormal_reproductive_system | 0.67192241 |
| 81 | MP0005389_reproductive_system_phenotype | 0.66459789 |
| 82 | MP0003315_abnormal_perineum_morphology | 0.66087683 |
| 83 | MP0009250_abnormal_appendicular_skeleto | 0.66048558 |
| 84 | MP0001984_abnormal_olfaction | 0.66000898 |
| 85 | MP0002638_abnormal_pupillary_reflex | 0.65843644 |
| 86 | MP0005645_abnormal_hypothalamus_physiol | 0.65732646 |
| 87 | MP0005391_vision/eye_phenotype | 0.65106924 |
| 88 | MP0010678_abnormal_skin_adnexa | 0.65020913 |
| 89 | MP0002697_abnormal_eye_size | 0.64908273 |
| 90 | MP0002184_abnormal_innervation | 0.62393361 |
| 91 | MP0004142_abnormal_muscle_tone | 0.62362096 |
| 92 | MP0008873_increased_physiological_sensi | 0.62336386 |
| 93 | MP0002102_abnormal_ear_morphology | 0.59615452 |
| 94 | MP0005257_abnormal_intraocular_pressure | 0.59571863 |
| 95 | MP0000427_abnormal_hair_cycle | 0.59183765 |
| 96 | MP0005195_abnormal_posterior_eye | 0.58471664 |
| 97 | MP0004859_abnormal_synaptic_plasticity | 0.57775063 |
| 98 | MP0002735_abnormal_chemical_nociception | 0.57496023 |
| 99 | MP0003122_maternal_imprinting | 0.56620084 |
| 100 | MP0004130_abnormal_muscle_cell | 0.56113102 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Difficulty running (HP:0009046) | 8.98416366 |
| 2 | Hip dysplasia (HP:0001385) | 8.26266096 |
| 3 | Achilles tendon contracture (HP:0001771) | 7.53663331 |
| 4 | Abnormality of the Achilles tendon (HP:0005109) | 6.87613041 |
| 5 | Hip contracture (HP:0003273) | 6.46872627 |
| 6 | Hypoplasia of the pons (HP:0012110) | 6.23510586 |
| 7 | Abnormality of the pons (HP:0007361) | 5.52459458 |
| 8 | Limited hip movement (HP:0008800) | 5.26448381 |
| 9 | Opisthotonus (HP:0002179) | 5.06590266 |
| 10 | Poor suck (HP:0002033) | 4.89629103 |
| 11 | Knee flexion contracture (HP:0006380) | 3.92319780 |
| 12 | Scapular winging (HP:0003691) | 3.87003543 |
| 13 | Restlessness (HP:0000711) | 3.72539861 |
| 14 | Hyperglycinemia (HP:0002154) | 3.68589328 |
| 15 | Impaired smooth pursuit (HP:0007772) | 3.53585940 |
| 16 | Dyskinesia (HP:0100660) | 3.52095252 |
| 17 | Poor eye contact (HP:0000817) | 3.22813753 |
| 18 | Increased hepatocellular lipid droplets (HP:0006565) | 3.10316398 |
| 19 | Asplenia (HP:0001746) | 2.90387763 |
| 20 | Gowers sign (HP:0003391) | 2.89752535 |
| 21 | Thoracolumbar scoliosis (HP:0002944) | 2.85481549 |
| 22 | Spondylolisthesis (HP:0003302) | 2.84185475 |
| 23 | Progressive microcephaly (HP:0000253) | 2.82823122 |
| 24 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.81198368 |
| 25 | Parakeratosis (HP:0001036) | 2.74853957 |
| 26 | Abnormality of the periventricular white matter (HP:0002518) | 2.69705163 |
| 27 | Renal Fanconi syndrome (HP:0001994) | 2.68958956 |
| 28 | Short femoral neck (HP:0100864) | 2.67193044 |
| 29 | Waddling gait (HP:0002515) | 2.66932629 |
| 30 | Pancreatic fibrosis (HP:0100732) | 2.66874067 |
| 31 | Lipid accumulation in hepatocytes (HP:0006561) | 2.56938662 |
| 32 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.55400637 |
| 33 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.52042729 |
| 34 | Severe global developmental delay (HP:0011344) | 2.47596267 |
| 35 | Sacral dimple (HP:0000960) | 2.44765861 |
| 36 | Fasciculations (HP:0002380) | 2.44463978 |
| 37 | Hypoplasia of the brainstem (HP:0002365) | 2.42203465 |
| 38 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 2.42203465 |
| 39 | Tetraplegia (HP:0002445) | 2.38124508 |
| 40 | Increased intramyocellular lipid droplets (HP:0012240) | 2.37423628 |
| 41 | Abnormality of the shoulder girdle musculature (HP:0001435) | 2.36276252 |
| 42 | Impaired social interactions (HP:0000735) | 2.33537980 |
| 43 | Abnormal social behavior (HP:0012433) | 2.33537980 |
| 44 | Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108) | 2.31017076 |
| 45 | Potter facies (HP:0002009) | 2.26362999 |
| 46 | Facial shape deformation (HP:0011334) | 2.26362999 |
| 47 | Abnormal number of erythroid precursors (HP:0012131) | 2.24912412 |
| 48 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.20524174 |
| 49 | Delayed epiphyseal ossification (HP:0002663) | 2.18278001 |
| 50 | Prominent metopic ridge (HP:0005487) | 2.15222438 |
| 51 | Abnormal biliary tract physiology (HP:0012439) | 2.13554872 |
| 52 | Bile duct proliferation (HP:0001408) | 2.13554872 |
| 53 | Abnormality of the metopic suture (HP:0005556) | 2.13541922 |
| 54 | Small epiphyses (HP:0010585) | 2.12725038 |
| 55 | Abnormality of the anterior horn cell (HP:0006802) | 2.12653660 |
| 56 | Degeneration of anterior horn cells (HP:0002398) | 2.12653660 |
| 57 | Abnormal drinking behavior (HP:0030082) | 2.11100182 |
| 58 | Polydipsia (HP:0001959) | 2.11100182 |
| 59 | Nasal speech (HP:0001611) | 2.06133748 |
| 60 | Mesomelia (HP:0003027) | 2.05778245 |
| 61 | Female pseudohermaphroditism (HP:0010458) | 2.05167180 |
| 62 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.04836019 |
| 63 | Supernumerary spleens (HP:0009799) | 2.04692900 |
| 64 | Tubular atrophy (HP:0000092) | 2.03326922 |
| 65 | Brushfield spots (HP:0001088) | 2.02261720 |
| 66 | Abnormality of the vocal cords (HP:0008777) | 2.00506224 |
| 67 | Autoimmune thrombocytopenia (HP:0001973) | 2.00471664 |
| 68 | Genetic anticipation (HP:0003743) | 1.98380494 |
| 69 | Abnormality of the lower motor neuron (HP:0002366) | 1.95334036 |
| 70 | Ulnar deviation of the wrist (HP:0003049) | 1.94271344 |
| 71 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.93184931 |
| 72 | Short 4th metacarpal (HP:0010044) | 1.93184931 |
| 73 | Wide intermamillary distance (HP:0006610) | 1.92000120 |
| 74 | Exertional dyspnea (HP:0002875) | 1.89925144 |
| 75 | Aplasia/hypoplasia of the femur (HP:0005613) | 1.87070054 |
| 76 | Death in childhood (HP:0003819) | 1.86529124 |
| 77 | Tubulointerstitial fibrosis (HP:0005576) | 1.85267244 |
| 78 | Molar tooth sign on MRI (HP:0002419) | 1.83427754 |
| 79 | Abnormality of midbrain morphology (HP:0002418) | 1.83427754 |
| 80 | Congenital, generalized hypertrichosis (HP:0004540) | 1.81936124 |
| 81 | Chronic hepatic failure (HP:0100626) | 1.79224072 |
| 82 | Increased muscle lipid content (HP:0009058) | 1.79134450 |
| 83 | Abnormality of the fingertips (HP:0001211) | 1.78762912 |
| 84 | Abnormality of the musculature of the hand (HP:0001421) | 1.78650223 |
| 85 | Supranuclear gaze palsy (HP:0000605) | 1.75996793 |
| 86 | Myokymia (HP:0002411) | 1.74111022 |
| 87 | Adrenal hypoplasia (HP:0000835) | 1.71554287 |
| 88 | Macrocytic anemia (HP:0001972) | 1.71254225 |
| 89 | Respiratory difficulties (HP:0002880) | 1.70469232 |
| 90 | Mitochondrial inheritance (HP:0001427) | 1.68933565 |
| 91 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 1.68893756 |
| 92 | Primary adrenal insufficiency (HP:0008207) | 1.68285271 |
| 93 | Abnormality of chromosome stability (HP:0003220) | 1.67981590 |
| 94 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.67596905 |
| 95 | Hyperphosphaturia (HP:0003109) | 1.67050860 |
| 96 | Pancreatic cysts (HP:0001737) | 1.66537008 |
| 97 | Abnormality of renal resorption (HP:0011038) | 1.65415137 |
| 98 | Aplasia/Hypoplasia involving the pelvis (HP:0009103) | 1.65380212 |
| 99 | Gonadal dysgenesis (HP:0000133) | 1.62324142 |
| 100 | Epiphyseal dysplasia (HP:0002656) | 1.62305337 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | LIMK1 | 7.70263865 |
| 2 | MAP4K2 | 4.01094572 |
| 3 | MAP4K1 | 3.93441170 |
| 4 | TESK1 | 3.77555413 |
| 5 | WNK4 | 3.16785576 |
| 6 | NLK | 3.08767012 |
| 7 | TXK | 2.64214661 |
| 8 | SGK2 | 2.03350768 |
| 9 | BMPR1B | 1.89336408 |
| 10 | ACVR1B | 1.78881232 |
| 11 | CSF1R | 1.71109070 |
| 12 | SGK223 | 1.60044431 |
| 13 | SGK494 | 1.60044431 |
| 14 | PRKCG | 1.56123730 |
| 15 | NME1 | 1.55575805 |
| 16 | MINK1 | 1.54398029 |
| 17 | OXSR1 | 1.53927444 |
| 18 | CDC7 | 1.51532149 |
| 19 | PIK3CA | 1.51316608 |
| 20 | NTRK2 | 1.51294744 |
| 21 | DYRK1A | 1.49647474 |
| 22 | STK39 | 1.47449542 |
| 23 | INSRR | 1.41995137 |
| 24 | ADRBK2 | 1.39521324 |
| 25 | PLK2 | 1.38165235 |
| 26 | PKN1 | 1.32396645 |
| 27 | CDC42BPA | 1.30927020 |
| 28 | CSNK1G1 | 1.29181113 |
| 29 | PDK1 | 1.26266442 |
| 30 | CASK | 1.17389801 |
| 31 | TNIK | 1.14852536 |
| 32 | PRKD3 | 1.04064534 |
| 33 | CDK19 | 0.99334453 |
| 34 | TGFBR1 | 0.96571045 |
| 35 | SGK3 | 0.94661017 |
| 36 | RPS6KA5 | 0.84237907 |
| 37 | WNK3 | 0.82762115 |
| 38 | PRKCQ | 0.81834422 |
| 39 | PAK1 | 0.80894357 |
| 40 | LCK | 0.79201706 |
| 41 | MUSK | 0.77556122 |
| 42 | FRK | 0.77528871 |
| 43 | IKBKE | 0.76359693 |
| 44 | MAP2K7 | 0.75623864 |
| 45 | CSNK2A2 | 0.74911529 |
| 46 | LRRK2 | 0.74588126 |
| 47 | OBSCN | 0.74199643 |
| 48 | LYN | 0.71861806 |
| 49 | CSNK1A1 | 0.71415142 |
| 50 | EPHA4 | 0.70616454 |
| 51 | BRD4 | 0.70408908 |
| 52 | MAP3K9 | 0.63944149 |
| 53 | GRK1 | 0.63179993 |
| 54 | MAP3K4 | 0.63055131 |
| 55 | ITK | 0.61184774 |
| 56 | DYRK2 | 0.60863249 |
| 57 | MARK1 | 0.60244862 |
| 58 | FYN | 0.57695628 |
| 59 | ADRBK1 | 0.57006500 |
| 60 | CSNK2A1 | 0.56429988 |
| 61 | MST1R | 0.55951454 |
| 62 | MYLK | 0.54358684 |
| 63 | IGF1R | 0.53062207 |
| 64 | SYK | 0.52732892 |
| 65 | DYRK3 | 0.50797091 |
| 66 | PRKCA | 0.47780394 |
| 67 | MAPK15 | 0.47596630 |
| 68 | ICK | 0.46344017 |
| 69 | TIE1 | 0.46048685 |
| 70 | PDPK1 | 0.45837397 |
| 71 | WNK1 | 0.45716504 |
| 72 | MAPK4 | 0.45489426 |
| 73 | SGK1 | 0.45031039 |
| 74 | MAPK3 | 0.43184369 |
| 75 | MAPK9 | 0.40817733 |
| 76 | ROCK2 | 0.39817593 |
| 77 | MAPK14 | 0.38817809 |
| 78 | RPS6KA6 | 0.38010730 |
| 79 | CDK5 | 0.37366771 |
| 80 | PIM2 | 0.36478732 |
| 81 | CDK15 | 0.36291710 |
| 82 | KDR | 0.35874447 |
| 83 | ROCK1 | 0.34413867 |
| 84 | RPS6KL1 | 0.34129074 |
| 85 | RPS6KC1 | 0.34129074 |
| 86 | IRAK2 | 0.33086431 |
| 87 | CDK14 | 0.32774642 |
| 88 | IKBKB | 0.32486526 |
| 89 | PRKACA | 0.32467661 |
| 90 | CDK18 | 0.31673278 |
| 91 | MAP2K6 | 0.31562937 |
| 92 | CDK2 | 0.30788756 |
| 93 | GSK3A | 0.29922661 |
| 94 | DYRK1B | 0.28611040 |
| 95 | NTRK3 | 0.28473200 |
| 96 | PAK3 | 0.28460862 |
| 97 | MATK | 0.27917463 |
| 98 | CDK11A | 0.27909095 |
| 99 | FES | 0.27887015 |
| 100 | MAPK13 | 0.27794144 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.77381680 |
| 2 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 4.73067500 |
| 3 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 4.18533639 |
| 4 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.45307339 |
| 5 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.23199875 |
| 6 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.19826529 |
| 7 | Sulfur relay system_Homo sapiens_hsa04122 | 10.2276088 |
| 8 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.97713860 |
| 9 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.75561362 |
| 10 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.55831773 |
| 11 | Measles_Homo sapiens_hsa05162 | 1.55635359 |
| 12 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.51147375 |
| 13 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.50352463 |
| 14 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.36056465 |
| 15 | Phototransduction_Homo sapiens_hsa04744 | 1.23089054 |
| 16 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.12157922 |
| 17 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.06309754 |
| 18 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.98134530 |
| 19 | Olfactory transduction_Homo sapiens_hsa04740 | 0.94205599 |
| 20 | Nicotine addiction_Homo sapiens_hsa05033 | 0.93308324 |
| 21 | DNA replication_Homo sapiens_hsa03030 | 0.92354957 |
| 22 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.91856379 |
| 23 | Apoptosis_Homo sapiens_hsa04210 | 0.90638005 |
| 24 | Parkinsons disease_Homo sapiens_hsa05012 | 0.89891834 |
| 25 | Malaria_Homo sapiens_hsa05144 | 0.84700834 |
| 26 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.82480075 |
| 27 | Alzheimers disease_Homo sapiens_hsa05010 | 0.79900979 |
| 28 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.77510943 |
| 29 | Carbon metabolism_Homo sapiens_hsa01200 | 0.76843536 |
| 30 | Retinol metabolism_Homo sapiens_hsa00830 | 0.73793057 |
| 31 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.72985885 |
| 32 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.71422645 |
| 33 | Thyroid cancer_Homo sapiens_hsa05216 | 0.70466046 |
| 34 | Taste transduction_Homo sapiens_hsa04742 | 0.68872706 |
| 35 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.68682798 |
| 36 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.68679378 |
| 37 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.67855147 |
| 38 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.67593987 |
| 39 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.66751580 |
| 40 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.64994110 |
| 41 | Influenza A_Homo sapiens_hsa05164 | 0.63671156 |
| 42 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.63134328 |
| 43 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.62894888 |
| 44 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.58579849 |
| 45 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.58191571 |
| 46 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.57263730 |
| 47 | Axon guidance_Homo sapiens_hsa04360 | 0.56510652 |
| 48 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.55496797 |
| 49 | Salivary secretion_Homo sapiens_hsa04970 | 0.55236801 |
| 50 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.50854455 |
| 51 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.48941985 |
| 52 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.47382125 |
| 53 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.47006745 |
| 54 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.45478064 |
| 55 | Metabolic pathways_Homo sapiens_hsa01100 | 0.44985206 |
| 56 | Legionellosis_Homo sapiens_hsa05134 | 0.44374734 |
| 57 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.43602056 |
| 58 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.43454628 |
| 59 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.42772196 |
| 60 | Morphine addiction_Homo sapiens_hsa05032 | 0.41832446 |
| 61 | GABAergic synapse_Homo sapiens_hsa04727 | 0.41328498 |
| 62 | Huntingtons disease_Homo sapiens_hsa05016 | 0.40602206 |
| 63 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.40459855 |
| 64 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.40372481 |
| 65 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.40356682 |
| 66 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.40182366 |
| 67 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.39653299 |
| 68 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.38670264 |
| 69 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.35095205 |
| 70 | Peroxisome_Homo sapiens_hsa04146 | 0.34624226 |
| 71 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.33479849 |
| 72 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.33100500 |
| 73 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.32223016 |
| 74 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.31953054 |
| 75 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.29894551 |
| 76 | Alcoholism_Homo sapiens_hsa05034 | 0.29522083 |
| 77 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.28874257 |
| 78 | Purine metabolism_Homo sapiens_hsa00230 | 0.28672580 |
| 79 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.28420310 |
| 80 | Insulin secretion_Homo sapiens_hsa04911 | 0.27802360 |
| 81 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.27724766 |
| 82 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.26995768 |
| 83 | Circadian entrainment_Homo sapiens_hsa04713 | 0.26330043 |
| 84 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.23746044 |
| 85 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.21514748 |
| 86 | Allograft rejection_Homo sapiens_hsa05330 | 0.21462421 |
| 87 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.21258830 |
| 88 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.20369063 |
| 89 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.19980340 |
| 90 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.19965444 |
| 91 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.19923518 |
| 92 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.19665481 |
| 93 | Cocaine addiction_Homo sapiens_hsa05030 | 0.19523015 |
| 94 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.19131541 |
| 95 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.18870002 |
| 96 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.17705275 |
| 97 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.17101545 |
| 98 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.16951815 |
| 99 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.16858339 |
| 100 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.16767429 |

