Rank | Gene Set | Z-score |
---|---|---|
1 | glomerular visceral epithelial cell development (GO:0072015) | 6.44897956 |
2 | glomerular epithelial cell development (GO:0072310) | 5.80097504 |
3 | glomerular basement membrane development (GO:0032836) | 5.11805485 |
4 | COPI coating of Golgi vesicle (GO:0048205) | 4.17695501 |
5 | Golgi transport vesicle coating (GO:0048200) | 4.17695501 |
6 | positive regulation of histone deacetylation (GO:0031065) | 4.14082448 |
7 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.11320320 |
8 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.11320320 |
9 | cell adhesion mediated by integrin (GO:0033627) | 3.91043147 |
10 | protein heterotrimerization (GO:0070208) | 3.81208042 |
11 | mesodermal cell differentiation (GO:0048333) | 3.60182343 |
12 | apoptotic cell clearance (GO:0043277) | 3.58717954 |
13 | endothelial cell chemotaxis (GO:0035767) | 3.56735428 |
14 | sequestering of extracellular ligand from receptor (GO:0035581) | 3.51800981 |
15 | hypotonic response (GO:0006971) | 3.49474749 |
16 | barbed-end actin filament capping (GO:0051016) | 3.47311406 |
17 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.45628974 |
18 | hemidesmosome assembly (GO:0031581) | 3.43981736 |
19 | endodermal cell differentiation (GO:0035987) | 3.43925219 |
20 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.39924412 |
21 | vascular endothelial growth factor signaling pathway (GO:0038084) | 3.37582730 |
22 | positive regulation of osteoblast proliferation (GO:0033690) | 3.35967046 |
23 | type B pancreatic cell proliferation (GO:0044342) | 3.33989522 |
24 | membrane raft organization (GO:0031579) | 3.32974877 |
25 | skin morphogenesis (GO:0043589) | 3.32851821 |
26 | epithelial cell-cell adhesion (GO:0090136) | 3.25125612 |
27 | positive thymic T cell selection (GO:0045059) | 3.24919773 |
28 | protein localization to endosome (GO:0036010) | 3.24804482 |
29 | positive regulation of p38MAPK cascade (GO:1900745) | 3.16371873 |
30 | cell-substrate adherens junction assembly (GO:0007045) | 3.15798352 |
31 | focal adhesion assembly (GO:0048041) | 3.15798352 |
32 | bone trabecula formation (GO:0060346) | 3.15498132 |
33 | negative regulation of fatty acid transport (GO:2000192) | 3.14819602 |
34 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 3.14169104 |
35 | cell migration involved in sprouting angiogenesis (GO:0002042) | 3.13219098 |
36 | collagen fibril organization (GO:0030199) | 3.12804007 |
37 | negative regulation of chondrocyte differentiation (GO:0032331) | 3.12194304 |
38 | adherens junction assembly (GO:0034333) | 3.11765078 |
39 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.09626166 |
40 | membrane protein ectodomain proteolysis (GO:0006509) | 3.09085672 |
41 | regulation of extracellular matrix disassembly (GO:0010715) | 3.08281753 |
42 | actin filament depolymerization (GO:0030042) | 3.07815120 |
43 | wound healing, spreading of cells (GO:0044319) | 3.05364521 |
44 | protein hydroxylation (GO:0018126) | 3.04781052 |
45 | positive regulation of protein deacetylation (GO:0090312) | 3.04599589 |
46 | regulation of apoptotic process involved in morphogenesis (GO:1902337) | 3.04056830 |
47 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 3.03724628 |
48 | extracellular fibril organization (GO:0043206) | 3.00971397 |
49 | stress fiber assembly (GO:0043149) | 2.99560916 |
50 | positive regulation of nuclease activity (GO:0032075) | 2.97431451 |
51 | heparan sulfate proteoglycan biosynthetic process (GO:0015012) | 2.97235348 |
52 | peptidyl-proline hydroxylation (GO:0019511) | 2.97125819 |
53 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 2.94799301 |
54 | regulation of gamma-delta T cell activation (GO:0046643) | 2.93733434 |
55 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.93731655 |
56 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 2.93728663 |
57 | response to laminar fluid shear stress (GO:0034616) | 2.92121977 |
58 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 2.90962120 |
59 | negative regulation of anoikis (GO:2000811) | 2.90524095 |
60 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 2.88718437 |
61 | fibril organization (GO:0097435) | 2.87139142 |
62 | iron ion import (GO:0097286) | 2.86812361 |
63 | positive regulation of extracellular matrix organization (GO:1903055) | 2.86721725 |
64 | regulation of transforming growth factor beta2 production (GO:0032909) | 2.85486157 |
65 | blood vessel endothelial cell migration (GO:0043534) | 2.85311667 |
66 | positive regulation of cell adhesion mediated by integrin (GO:0033630) | 2.83929614 |
67 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 2.83848899 |
68 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.83595837 |
69 | SMAD protein complex assembly (GO:0007183) | 2.82503367 |
70 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.81928883 |
71 | mannose metabolic process (GO:0006013) | 2.80501549 |
72 | natural killer cell differentiation (GO:0001779) | 2.78154197 |
73 | hepatocyte apoptotic process (GO:0097284) | 2.74887807 |
74 | substrate-dependent cell migration (GO:0006929) | 2.73009185 |
75 | extracellular matrix assembly (GO:0085029) | 2.71461538 |
76 | chondrocyte proliferation (GO:0035988) | 2.71232382 |
77 | regulation of nuclease activity (GO:0032069) | 2.68058633 |
78 | cortical actin cytoskeleton organization (GO:0030866) | 2.67380188 |
79 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 2.67036457 |
80 | endothelial cell morphogenesis (GO:0001886) | 2.66514352 |
81 | kidney mesenchyme development (GO:0072074) | 2.66332052 |
82 | wound healing, spreading of epidermal cells (GO:0035313) | 2.66216000 |
83 | regulation of early endosome to late endosome transport (GO:2000641) | 2.65296920 |
84 | regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307) | 2.65090411 |
85 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.64954786 |
86 | chondrocyte development (GO:0002063) | 2.64265762 |
87 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 2.63451870 |
88 | positive regulation of natural killer cell differentiation (GO:0032825) | 2.62934671 |
89 | germ cell migration (GO:0008354) | 2.62717168 |
90 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 2.62553161 |
91 | positive regulation of endothelial cell migration (GO:0010595) | 2.62133988 |
92 | regulation of osteoblast proliferation (GO:0033688) | 2.61150977 |
93 | endoplasmic reticulum unfolded protein response (GO:0030968) | 2.60603200 |
94 | positive regulation of epithelial to mesenchymal transition (GO:0010718) | 2.59849236 |
95 | semaphorin-plexin signaling pathway (GO:0071526) | 2.58793355 |
96 | negative regulation of protein localization to plasma membrane (GO:1903077) | 2.58071566 |
97 | regulation of p38MAPK cascade (GO:1900744) | 2.57121803 |
98 | positive regulation of receptor recycling (GO:0001921) | 2.57099091 |
99 | chondroitin sulfate biosynthetic process (GO:0030206) | 2.57066851 |
100 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.56481971 |
101 | vesicle coating (GO:0006901) | 2.56429074 |
102 | negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394) | 2.55900148 |
103 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241) | 2.53749941 |
104 | response to fluid shear stress (GO:0034405) | 2.53391733 |
105 | protein targeting to plasma membrane (GO:0072661) | 2.53065414 |
106 | multicellular organismal macromolecule metabolic process (GO:0044259) | 2.52584188 |
107 | positive regulation of epithelial cell migration (GO:0010634) | 2.52516574 |
108 | pericardium development (GO:0060039) | 2.52026938 |
109 | substrate adhesion-dependent cell spreading (GO:0034446) | 2.51517149 |
110 | multicellular organismal catabolic process (GO:0044243) | 2.51372590 |
111 | regulation of T cell tolerance induction (GO:0002664) | 2.50808471 |
112 | muscle cell migration (GO:0014812) | 2.50548741 |
113 | pathway-restricted SMAD protein phosphorylation (GO:0060389) | 2.50227827 |
114 | growth hormone receptor signaling pathway (GO:0060396) | 2.49785537 |
115 | COPII vesicle coating (GO:0048208) | 2.49704747 |
116 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.49684324 |
117 | cellular response to unfolded protein (GO:0034620) | 2.49073587 |
118 | hyaluronan catabolic process (GO:0030214) | 2.48707842 |
119 | thymic T cell selection (GO:0045061) | 2.48659318 |
120 | pinocytosis (GO:0006907) | 2.47296800 |
121 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.46796362 |
122 | collagen metabolic process (GO:0032963) | 2.46041753 |
123 | regulation of anoikis (GO:2000209) | 2.43784197 |
124 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.42612984 |
125 | collagen catabolic process (GO:0030574) | 2.42584287 |
126 | negative regulation of cell size (GO:0045792) | 2.41976123 |
127 | maternal placenta development (GO:0001893) | 2.40366769 |
128 | NLS-bearing protein import into nucleus (GO:0006607) | 2.39938935 |
129 | axon extension involved in axon guidance (GO:0048846) | 2.39187461 |
130 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 2.39187461 |
131 | negative regulation of smooth muscle cell migration (GO:0014912) | 2.38820773 |
132 | cellular response to vitamin (GO:0071295) | 2.37355135 |
133 | integrin-mediated signaling pathway (GO:0007229) | 2.37328222 |
134 | multicellular organismal metabolic process (GO:0044236) | 2.37019324 |
135 | cell-substrate junction assembly (GO:0007044) | 2.37002385 |
136 | positive T cell selection (GO:0043368) | 2.35906230 |
137 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.35801071 |
138 | cellular response to vitamin D (GO:0071305) | 2.35720187 |
139 | endothelial tube morphogenesis (GO:0061154) | 2.35450339 |
140 | morphogenesis of an endothelium (GO:0003159) | 2.35450339 |
141 | protein retention in ER lumen (GO:0006621) | 2.35437499 |
142 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.35392473 |
143 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 2.34525889 |
144 | positive regulation of tolerance induction (GO:0002645) | 2.34269286 |
145 | positive regulation of transforming growth factor beta receptor signaling pathway (GO:0030511) | 2.33579984 |
146 | ER-nucleus signaling pathway (GO:0006984) | 2.33451315 |
147 | basement membrane organization (GO:0071711) | 2.33423535 |
148 | endothelial cell migration (GO:0043542) | 2.31591155 |
149 | hippo signaling (GO:0035329) | 2.31518137 |
150 | cellular response to growth hormone stimulus (GO:0071378) | 2.31161575 |
151 | receptor catabolic process (GO:0032801) | 2.29467251 |
152 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 2.27402156 |
153 | extracellular matrix disassembly (GO:0022617) | 2.27138462 |
154 | negative T cell selection (GO:0043383) | 2.25811538 |
155 | glomerulus development (GO:0032835) | 2.25719653 |
156 | regulation of tight junction assembly (GO:2000810) | 2.25233558 |
157 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.25131361 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.87358540 |
2 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 3.68518229 |
3 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.21158225 |
4 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.07435868 |
5 | MYC_22102868_ChIP-Seq_BL_Human | 2.86737971 |
6 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.68141670 |
7 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.66552369 |
8 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.64617355 |
9 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.55561945 |
10 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.49304494 |
11 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 2.31319951 |
12 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 2.28269447 |
13 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.28073933 |
14 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.27404504 |
15 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.24696569 |
16 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.16364346 |
17 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.12675771 |
18 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.12493926 |
19 | * RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 2.08258660 |
20 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 2.07188933 |
21 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.06457584 |
22 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.00091522 |
23 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.96501375 |
24 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.96079371 |
25 | MAF_26560356_Chip-Seq_TH1_Human | 1.92530844 |
26 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.90451231 |
27 | UTX_26944678_Chip-Seq_JUKART_Human | 1.87883393 |
28 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.76032894 |
29 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.75669385 |
30 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.70714752 |
31 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.69511920 |
32 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.67179898 |
33 | * CJUN_26792858_Chip-Seq_BT549_Human | 1.66732436 |
34 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.61612664 |
35 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.59006713 |
36 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.58133086 |
37 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.56322364 |
38 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.55914904 |
39 | MYB_26560356_Chip-Seq_TH2_Human | 1.55838894 |
40 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.55565064 |
41 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.54123817 |
42 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.54060567 |
43 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.53334797 |
44 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.52289151 |
45 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.51989267 |
46 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.50781226 |
47 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.49967723 |
48 | ATF3_27146783_Chip-Seq_COLON_Human | 1.48715009 |
49 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.46913668 |
50 | * TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.46037881 |
51 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.45683127 |
52 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.44779965 |
53 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.44218810 |
54 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.43598771 |
55 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.42839201 |
56 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.41729744 |
57 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.41721392 |
58 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.41268307 |
59 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.41176858 |
60 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.40338667 |
61 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.39219606 |
62 | GATA1_19941826_ChIP-Seq_K562_Human | 1.37671270 |
63 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.36985985 |
64 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.35545602 |
65 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.35174324 |
66 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.34865686 |
67 | * ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.34815769 |
68 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.34022841 |
69 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.33070036 |
70 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.31870242 |
71 | MYB_26560356_Chip-Seq_TH1_Human | 1.30207167 |
72 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.30104591 |
73 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.28626929 |
74 | * ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.28504870 |
75 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.28076467 |
76 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.27686372 |
77 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.26940980 |
78 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.25976787 |
79 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.23183050 |
80 | GATA6_25053715_ChIP-Seq_YYC3_Human | 1.22133291 |
81 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.21673584 |
82 | * PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.21364709 |
83 | SPI1_23127762_ChIP-Seq_K562_Human | 1.20614699 |
84 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.18319439 |
85 | * SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.17781666 |
86 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.16524651 |
87 | KDM2B_26808549_Chip-Seq_K562_Human | 1.16414915 |
88 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.15721722 |
89 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.15024906 |
90 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.14742670 |
91 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.14395184 |
92 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.14381283 |
93 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.12759425 |
94 | * GATA2_19941826_ChIP-Seq_K562_Human | 1.11863342 |
95 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.11679874 |
96 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.11679874 |
97 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.09983211 |
98 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 1.09196332 |
99 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.08273170 |
100 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.08273170 |
101 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.07689874 |
102 | * TP53_23651856_ChIP-Seq_MEFs_Mouse | 1.07370068 |
103 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.07175114 |
104 | MAF_26560356_Chip-Seq_TH2_Human | 1.06040791 |
105 | * BRD4_25478319_ChIP-Seq_HGPS_Human | 1.05972164 |
106 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.05117341 |
107 | * TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.03993613 |
108 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.03855822 |
109 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.03402036 |
110 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.03371748 |
111 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.02841169 |
112 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.02511854 |
113 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.01086582 |
114 | * TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.00747664 |
115 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.00380591 |
116 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 0.99895204 |
117 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.98419172 |
118 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.97701890 |
119 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.97179572 |
120 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.96766245 |
121 | * SOX2_20726797_ChIP-Seq_SW620_Human | 0.96718718 |
122 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.96454020 |
123 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.95797690 |
124 | * SMC1_22415368_ChIP-Seq_MEFs_Mouse | 0.95683410 |
125 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.95127918 |
126 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.92984211 |
127 | CREB1_26743006_Chip-Seq_LNCaP_Human | 0.92947183 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008438_abnormal_cutaneous_collagen | 4.03811128 |
2 | MP0003705_abnormal_hypodermis_morpholog | 3.92913528 |
3 | MP0003300_gastrointestinal_ulcer | 3.31394623 |
4 | MP0010352_gastrointestinal_tract_polyps | 2.96754708 |
5 | MP0006054_spinal_hemorrhage | 2.51175314 |
6 | MP0003279_aneurysm | 2.43899823 |
7 | MP0003950_abnormal_plasma_membrane | 2.28301037 |
8 | MP0005275_abnormal_skin_tensile | 2.22633544 |
9 | MP0003566_abnormal_cell_adhesion | 2.19448141 |
10 | MP0005623_abnormal_meninges_morphology | 2.11511660 |
11 | MP0005503_abnormal_tendon_morphology | 2.03325972 |
12 | MP0005076_abnormal_cell_differentiation | 2.00252943 |
13 | MP0004272_abnormal_basement_membrane | 1.86520186 |
14 | MP0009278_abnormal_bone_marrow | 1.84885744 |
15 | MP0003091_abnormal_cell_migration | 1.83640376 |
16 | MP0003303_peritoneal_inflammation | 1.79113582 |
17 | MP0005023_abnormal_wound_healing | 1.79061067 |
18 | MP0002166_altered_tumor_susceptibility | 1.73064956 |
19 | MP0003191_abnormal_cellular_cholesterol | 1.71996869 |
20 | MP0009384_cardiac_valve_regurgitation | 1.70799118 |
21 | MP0001542_abnormal_bone_strength | 1.58372224 |
22 | MP0001958_emphysema | 1.57110379 |
23 | MP0002877_abnormal_melanocyte_morpholog | 1.55894233 |
24 | MP0000685_abnormal_immune_system | 1.55784329 |
25 | MP0003283_abnormal_digestive_organ | 1.55045391 |
26 | MP0010234_abnormal_vibrissa_follicle | 1.54120615 |
27 | MP0000733_abnormal_muscle_development | 1.47131890 |
28 | MP0004808_abnormal_hematopoietic_stem | 1.45400814 |
29 | MP0004185_abnormal_adipocyte_glucose | 1.41713500 |
30 | MP0000537_abnormal_urethra_morphology | 1.39358652 |
31 | MP0001348_abnormal_lacrimal_gland | 1.37160445 |
32 | MP0000858_altered_metastatic_potential | 1.35313236 |
33 | MP0004947_skin_inflammation | 1.34749867 |
34 | MP0005257_abnormal_intraocular_pressure | 1.31284909 |
35 | MP0010307_abnormal_tumor_latency | 1.29720445 |
36 | MP0009053_abnormal_anal_canal | 1.28297773 |
37 | MP0002933_joint_inflammation | 1.28064381 |
38 | MP0005451_abnormal_body_composition | 1.26886599 |
39 | MP0004858_abnormal_nervous_system | 1.24812462 |
40 | MP0004233_abnormal_muscle_weight | 1.24111471 |
41 | MP0002060_abnormal_skin_morphology | 1.21758646 |
42 | MP0003436_decreased_susceptibility_to | 1.18744292 |
43 | MP0005164_abnormal_response_to | 1.18145439 |
44 | MP0002896_abnormal_bone_mineralization | 1.17835301 |
45 | MP0002006_tumorigenesis | 1.17760760 |
46 | MP0001533_abnormal_skeleton_physiology | 1.17473993 |
47 | MP0001873_stomach_inflammation | 1.17350376 |
48 | MP0001545_abnormal_hematopoietic_system | 1.16435415 |
49 | MP0005397_hematopoietic_system_phenotyp | 1.16435415 |
50 | MP0008961_abnormal_basal_metabolism | 1.14628533 |
51 | MP0010155_abnormal_intestine_physiology | 1.14491516 |
52 | MP0001849_ear_inflammation | 1.13966715 |
53 | MP0003763_abnormal_thymus_physiology | 1.12091991 |
54 | MP0010368_abnormal_lymphatic_system | 1.11083968 |
55 | MP0003045_fibrosis | 1.10525578 |
56 | MP0002998_abnormal_bone_remodeling | 1.09846887 |
57 | MP0000767_abnormal_smooth_muscle | 1.09250553 |
58 | MP0009333_abnormal_splenocyte_physiolog | 1.08186722 |
59 | MP0009780_abnormal_chondrocyte_physiolo | 1.07947015 |
60 | MP0002295_abnormal_pulmonary_circulatio | 1.07205490 |
61 | MP0005508_abnormal_skeleton_morphology | 1.06972500 |
62 | MP0000490_abnormal_crypts_of | 1.04219177 |
63 | MP0003828_pulmonary_edema | 1.04165809 |
64 | MP0003866_abnormal_defecation | 1.03665337 |
65 | MP0001915_intracranial_hemorrhage | 1.00414342 |
66 | MP0001879_abnormal_lymphatic_vessel | 0.99616082 |
67 | MP0000477_abnormal_intestine_morphology | 0.99513154 |
68 | MP0001243_abnormal_dermal_layer | 0.99189218 |
69 | MP0005390_skeleton_phenotype | 0.98113724 |
70 | MP0002396_abnormal_hematopoietic_system | 0.97148599 |
71 | MP0006082_CNS_inflammation | 0.96882757 |
72 | MP0005464_abnormal_platelet_physiology | 0.96716708 |
73 | MP0003448_altered_tumor_morphology | 0.96631694 |
74 | MP0003656_abnormal_erythrocyte_physiolo | 0.96037755 |
75 | MP0010030_abnormal_orbit_morphology | 0.94344683 |
76 | MP0005595_abnormal_vascular_smooth | 0.93888083 |
77 | MP0000751_myopathy | 0.93393153 |
78 | MP0005058_abnormal_lysosome_morphology | 0.93290390 |
79 | MP0005165_increased_susceptibility_to | 0.92680296 |
80 | MP0005621_abnormal_cell_physiology | 0.91094259 |
81 | MP0000762_abnormal_tongue_morphology | 0.90924287 |
82 | MP0000003_abnormal_adipose_tissue | 0.90902485 |
83 | MP0002405_respiratory_system_inflammati | 0.90387260 |
84 | MP0005197_abnormal_uvea_morphology | 0.89585721 |
85 | MP0003795_abnormal_bone_structure | 0.88726944 |
86 | MP0005375_adipose_tissue_phenotype | 0.87863838 |
87 | MP0005409_darkened_coat_color | 0.87853218 |
88 | MP0002168_other_aberrant_phenotype | 0.87088242 |
89 | MP0002135_abnormal_kidney_morphology | 0.86942012 |
90 | MP0003115_abnormal_respiratory_system | 0.86020325 |
91 | MP0002398_abnormal_bone_marrow | 0.85845490 |
92 | MP0003453_abnormal_keratinocyte_physiol | 0.85177142 |
93 | MP0005666_abnormal_adipose_tissue | 0.83389535 |
94 | MP0002128_abnormal_blood_circulation | 0.83332787 |
95 | MP0001614_abnormal_blood_vessel | 0.83293878 |
96 | MP0003941_abnormal_skin_development | 0.83243254 |
97 | MP0002089_abnormal_postnatal_growth/wei | 0.83072839 |
98 | MP0002925_abnormal_cardiovascular_devel | 0.82484878 |
99 | MP0000428_abnormal_craniofacial_morphol | 0.81241897 |
100 | MP0000013_abnormal_adipose_tissue | 0.80904370 |
101 | MP0002452_abnormal_antigen_presenting | 0.80708983 |
102 | MP0000465_gastrointestinal_hemorrhage | 0.80401947 |
103 | MP0002113_abnormal_skeleton_development | 0.80280180 |
104 | MP0004134_abnormal_chest_morphology | 0.79457170 |
105 | MP0001790_abnormal_immune_system | 0.79241120 |
106 | MP0005387_immune_system_phenotype | 0.79241120 |
107 | MP0002136_abnormal_kidney_physiology | 0.79027985 |
108 | MP0008260_abnormal_autophagy | 0.78983497 |
109 | MP0005501_abnormal_skin_physiology | 0.78011569 |
110 | MP0000703_abnormal_thymus_morphology | 0.77747943 |
111 | MP0009840_abnormal_foam_cell | 0.76283942 |
112 | MP0009250_abnormal_appendicular_skeleto | 0.76219247 |
113 | MP0002722_abnormal_immune_system | 0.75990967 |
114 | MP0000534_abnormal_ureter_morphology | 0.74525176 |
115 | MP0001819_abnormal_immune_cell | 0.74280747 |
116 | MP0002420_abnormal_adaptive_immunity | 0.74239876 |
117 | MP0005388_respiratory_system_phenotype | 0.73992120 |
118 | MP0002133_abnormal_respiratory_system | 0.73992120 |
119 | MP0003942_abnormal_urinary_system | 0.73400272 |
120 | MP0005000_abnormal_immune_tolerance | 0.72419637 |
121 | MP0000759_abnormal_skeletal_muscle | 0.71984780 |
122 | MP0003385_abnormal_body_wall | 0.71709828 |
123 | MP0001175_abnormal_lung_morphology | 0.71380661 |
124 | MP0003252_abnormal_bile_duct | 0.70902544 |
125 | MP0005083_abnormal_biliary_tract | 0.70897532 |
126 | MP0000462_abnormal_digestive_system | 0.70858651 |
127 | MP0001800_abnormal_humoral_immune | 0.70004473 |
128 | MP0000163_abnormal_cartilage_morphology | 0.69748008 |
129 | MP0002932_abnormal_joint_morphology | 0.69380211 |
130 | MP0005193_abnormal_anterior_eye | 0.69336899 |
131 | MP0004084_abnormal_cardiac_muscle | 0.69267977 |
132 | MP0009643_abnormal_urine_homeostasis | 0.69148354 |
133 | MP0004883_abnormal_blood_vessel | 0.68720744 |
134 | MP0001299_abnormal_eye_distance/ | 0.68647342 |
135 | MP0000249_abnormal_blood_vessel | 0.67128971 |
136 | MP0002108_abnormal_muscle_morphology | 0.65260134 |
137 | MP0004782_abnormal_surfactant_physiolog | 0.65060036 |
138 | MP0000627_abnormal_mammary_gland | 0.63622334 |
139 | MP0000343_altered_response_to | 0.61660049 |
140 | MP0004510_myositis | 0.61316132 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Protrusio acetabuli (HP:0003179) | 5.17814192 |
2 | Premature rupture of membranes (HP:0001788) | 4.70230900 |
3 | Cerebral aneurysm (HP:0004944) | 4.48646097 |
4 | Aortic aneurysm (HP:0004942) | 4.31276018 |
5 | Aortic dissection (HP:0002647) | 4.06570378 |
6 | Shallow orbits (HP:0000586) | 3.59870774 |
7 | Mesangial abnormality (HP:0001966) | 3.51910527 |
8 | Ankle contracture (HP:0006466) | 3.46025700 |
9 | Peritonitis (HP:0002586) | 3.27641667 |
10 | Dilatation of the ascending aorta (HP:0005111) | 3.22325950 |
11 | Mitral valve prolapse (HP:0001634) | 3.16668915 |
12 | Genu recurvatum (HP:0002816) | 3.03316266 |
13 | Focal segmental glomerulosclerosis (HP:0000097) | 2.98679230 |
14 | Atrophic scars (HP:0001075) | 2.95035979 |
15 | Short nail (HP:0001799) | 2.89473726 |
16 | Broad metatarsal (HP:0001783) | 2.88703372 |
17 | Aneurysm (HP:0002617) | 2.86592458 |
18 | Fragile skin (HP:0001030) | 2.75749569 |
19 | Abnormal albumin level (HP:0012116) | 2.73680111 |
20 | Hypoalbuminemia (HP:0003073) | 2.73680111 |
21 | Broad face (HP:0000283) | 2.70332241 |
22 | Bladder diverticulum (HP:0000015) | 2.67169173 |
23 | Cervical subluxation (HP:0003308) | 2.63199391 |
24 | Hematochezia (HP:0002573) | 2.62634784 |
25 | Aortic regurgitation (HP:0001659) | 2.62629464 |
26 | Increased density of long bones (HP:0006392) | 2.60421113 |
27 | Mitral stenosis (HP:0001718) | 2.48354219 |
28 | Soft skin (HP:0000977) | 2.42673178 |
29 | Autoimmune thrombocytopenia (HP:0001973) | 2.41029623 |
30 | Absent frontal sinuses (HP:0002688) | 2.40797843 |
31 | Blue sclerae (HP:0000592) | 2.37656137 |
32 | Bowel diverticulosis (HP:0005222) | 2.37132029 |
33 | Abnormality of the nasal mucosa (HP:0000433) | 2.36702325 |
34 | Nasal polyposis (HP:0100582) | 2.33709069 |
35 | Nonimmune hydrops fetalis (HP:0001790) | 2.32681136 |
36 | Follicular hyperkeratosis (HP:0007502) | 2.31001296 |
37 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.29299169 |
38 | Osteolytic defects of the hand bones (HP:0009699) | 2.29299169 |
39 | Abnormality of the peritoneum (HP:0002585) | 2.27890384 |
40 | Syringomyelia (HP:0003396) | 2.26786146 |
41 | Spinal cord lesions (HP:0100561) | 2.26786146 |
42 | Thin bony cortex (HP:0002753) | 2.26192585 |
43 | Aortic valve stenosis (HP:0001650) | 2.23227396 |
44 | Vascular tortuosity (HP:0004948) | 2.21813565 |
45 | Arterial tortuosity (HP:0005116) | 2.21494476 |
46 | Distal lower limb amyotrophy (HP:0008944) | 2.19410127 |
47 | Nephritis (HP:0000123) | 2.14997028 |
48 | Vertebral compression fractures (HP:0002953) | 2.13074025 |
49 | Overgrowth (HP:0001548) | 2.10644081 |
50 | Ulnar bowing (HP:0003031) | 2.09818830 |
51 | Rectal prolapse (HP:0002035) | 2.08630259 |
52 | Joint stiffness (HP:0001387) | 2.07281611 |
53 | Glomerulosclerosis (HP:0000096) | 2.06600004 |
54 | Cardiovascular calcification (HP:0011915) | 2.06450820 |
55 | Disproportionate tall stature (HP:0001519) | 2.06390587 |
56 | Deviation of the hallux (HP:0010051) | 2.06051098 |
57 | Distal upper limb amyotrophy (HP:0007149) | 2.05497068 |
58 | Upper limb amyotrophy (HP:0009129) | 2.05497068 |
59 | Hyperacusis (HP:0010780) | 2.04029451 |
60 | Severe short stature (HP:0003510) | 2.03562468 |
61 | Increased variability in muscle fiber diameter (HP:0003557) | 2.02442318 |
62 | Increased connective tissue (HP:0009025) | 2.02020613 |
63 | Wormian bones (HP:0002645) | 2.00562431 |
64 | Hallux valgus (HP:0001822) | 2.00488225 |
65 | Short 4th metacarpal (HP:0010044) | 2.00409355 |
66 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.00409355 |
67 | Radial bowing (HP:0002986) | 1.99310573 |
68 | Hand muscle atrophy (HP:0009130) | 1.98116308 |
69 | Persistence of primary teeth (HP:0006335) | 1.96484350 |
70 | Abnormality of the acetabulum (HP:0003170) | 1.95833636 |
71 | Bicuspid aortic valve (HP:0001647) | 1.95148311 |
72 | Coxa vara (HP:0002812) | 1.93931238 |
73 | Striae distensae (HP:0001065) | 1.93915194 |
74 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 1.93680108 |
75 | Slender build (HP:0001533) | 1.90011867 |
76 | Interstitial pulmonary disease (HP:0006530) | 1.89576079 |
77 | Abnormal delivery (HP:0001787) | 1.88776707 |
78 | Long toe (HP:0010511) | 1.88434846 |
79 | Camptodactyly of toe (HP:0001836) | 1.86640090 |
80 | Subacute progressive viral hepatitis (HP:0006572) | 1.86447743 |
81 | Increased mean platelet volume (HP:0011877) | 1.85558033 |
82 | Abnormality of carpal bone ossification (HP:0006257) | 1.83585141 |
83 | Ovoid vertebral bodies (HP:0003300) | 1.83449827 |
84 | Lymphangioma (HP:0100764) | 1.83402045 |
85 | Spinal cord compression (HP:0002176) | 1.82671169 |
86 | Ectopia lentis (HP:0001083) | 1.82540918 |
87 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.82392496 |
88 | Abnormality of dentin (HP:0010299) | 1.82121821 |
89 | Neonatal short-limb short stature (HP:0008921) | 1.81775393 |
90 | Delayed closure of the anterior fontanelle (HP:0001476) | 1.81520612 |
91 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.81232225 |
92 | Natal tooth (HP:0000695) | 1.79411689 |
93 | Abnormal platelet volume (HP:0011876) | 1.79039293 |
94 | Mitral regurgitation (HP:0001653) | 1.77978088 |
95 | Abnormal foot bone ossification (HP:0010675) | 1.77342372 |
96 | Flat acetabular roof (HP:0003180) | 1.76330716 |
97 | Tibial bowing (HP:0002982) | 1.76035496 |
98 | Joint laxity (HP:0001388) | 1.76006835 |
99 | Menorrhagia (HP:0000132) | 1.75789796 |
100 | Abnormality of skull ossification (HP:0002703) | 1.75213214 |
101 | Metaphyseal cupping (HP:0003021) | 1.74758089 |
102 | Abnormality of the 4th metacarpal (HP:0010012) | 1.74496375 |
103 | Osteoarthritis (HP:0002758) | 1.72601240 |
104 | Delayed cranial suture closure (HP:0000270) | 1.72246455 |
105 | Cupped ribs (HP:0000887) | 1.72093861 |
106 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.72088484 |
107 | Abnormality of the fingertips (HP:0001211) | 1.71635040 |
108 | Difficulty climbing stairs (HP:0003551) | 1.71613336 |
109 | Distal lower limb muscle weakness (HP:0009053) | 1.71590662 |
110 | Bowing of the arm (HP:0006488) | 1.71374913 |
111 | Bowed forearm bones (HP:0003956) | 1.71374913 |
112 | Pustule (HP:0200039) | 1.70858215 |
113 | Hyperextensible skin (HP:0000974) | 1.70749827 |
114 | Mild short stature (HP:0003502) | 1.70468875 |
115 | Wrist flexion contracture (HP:0001239) | 1.70166968 |
116 | Wide anterior fontanel (HP:0000260) | 1.69199165 |
117 | Biconcave vertebral bodies (HP:0004586) | 1.67392636 |
118 | Insomnia (HP:0100785) | 1.65619104 |
119 | Exostoses (HP:0100777) | 1.65460354 |
120 | Polycythemia (HP:0001901) | 1.65069106 |
121 | Flat cornea (HP:0007720) | 1.64880210 |
122 | Generalized amyotrophy (HP:0003700) | 1.64752022 |
123 | Type 1 muscle fiber predominance (HP:0003803) | 1.64388515 |
124 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.64082666 |
125 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.63934835 |
126 | Spinal rigidity (HP:0003306) | 1.63414839 |
127 | Abnormality of oral frenula (HP:0000190) | 1.62887790 |
128 | Elbow flexion contracture (HP:0002987) | 1.62827590 |
129 | Lumbar hyperlordosis (HP:0002938) | 1.62558694 |
130 | Renal duplication (HP:0000075) | 1.62270869 |
131 | Broad ribs (HP:0000885) | 1.61659927 |
132 | Abnormal ossification of hand bones (HP:0005921) | 1.61626189 |
133 | Glomerulonephritis (HP:0000099) | 1.60425857 |
134 | Enlarged penis (HP:0000040) | 1.60127707 |
135 | Abnormality of the calcaneus (HP:0008364) | 1.57808838 |
136 | Spondylolisthesis (HP:0003302) | 1.56974290 |
137 | Platyspondyly (HP:0000926) | 1.55719515 |
138 | Congenital glaucoma (HP:0001087) | 1.54635527 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIB3 | 4.20027386 |
2 | PKN2 | 3.21610151 |
3 | EEF2K | 3.12480494 |
4 | MAP3K10 | 2.94415351 |
5 | ERN1 | 2.84164746 |
6 | MST1R | 2.83316611 |
7 | TTN | 2.65420275 |
8 | TGFBR2 | 2.30387881 |
9 | STK10 | 2.18211665 |
10 | PTK6 | 2.13242850 |
11 | PRPF4B | 2.08838210 |
12 | MAP4K1 | 2.07614116 |
13 | MET | 2.04700533 |
14 | PDGFRA | 2.04531991 |
15 | SIK1 | 1.99254616 |
16 | RIPK1 | 1.94758031 |
17 | IRAK3 | 1.91509952 |
18 | PAK4 | 1.84823325 |
19 | LRRK2 | 1.81938642 |
20 | SMG1 | 1.74622037 |
21 | TESK1 | 1.72867269 |
22 | NTRK1 | 1.71053211 |
23 | CDK12 | 1.70086354 |
24 | LIMK1 | 1.64947952 |
25 | SCYL2 | 1.58715335 |
26 | FGFR4 | 1.55524426 |
27 | JAK3 | 1.43163719 |
28 | LATS2 | 1.42066474 |
29 | EPHB1 | 1.40315002 |
30 | TYK2 | 1.35597777 |
31 | KDR | 1.32395967 |
32 | LATS1 | 1.31732144 |
33 | DDR2 | 1.31184003 |
34 | PAK2 | 1.31152403 |
35 | RPS6KA4 | 1.29685512 |
36 | MOS | 1.29039028 |
37 | EPHB2 | 1.26138369 |
38 | CDC42BPA | 1.23474317 |
39 | STK38 | 1.23177765 |
40 | MAP3K3 | 1.23074417 |
41 | ZAP70 | 1.20231837 |
42 | ERBB4 | 1.18893110 |
43 | BMX | 1.17783550 |
44 | JAK1 | 1.14542446 |
45 | PTK2 | 1.13763649 |
46 | ICK | 1.13698792 |
47 | PDGFRB | 1.12510289 |
48 | DYRK1B | 1.07344495 |
49 | GRK6 | 1.06124903 |
50 | FRK | 1.04281236 |
51 | TBK1 | 1.01378918 |
52 | MAP3K6 | 1.00320220 |
53 | CDK6 | 0.98826172 |
54 | NEK2 | 0.98786506 |
55 | MTOR | 0.98457855 |
56 | MAP2K3 | 0.97455975 |
57 | TGFBR1 | 0.96956861 |
58 | ITK | 0.96907518 |
59 | FGFR3 | 0.94493921 |
60 | MAP3K13 | 0.93935790 |
61 | STK3 | 0.92840469 |
62 | MAP3K2 | 0.92056371 |
63 | TRPM7 | 0.91860040 |
64 | MAP3K14 | 0.90696953 |
65 | DMPK | 0.89626764 |
66 | ROCK2 | 0.89126468 |
67 | CAMK1D | 0.88372224 |
68 | CDK8 | 0.88303882 |
69 | MAP3K8 | 0.87724501 |
70 | RPS6KA2 | 0.86403524 |
71 | TESK2 | 0.84087815 |
72 | PTK2B | 0.83298483 |
73 | CSK | 0.82498961 |
74 | TAOK2 | 0.80148191 |
75 | PRKCH | 0.76114909 |
76 | JAK2 | 0.75620014 |
77 | TAOK1 | 0.75573611 |
78 | EIF2AK1 | 0.74187091 |
79 | RET | 0.71710950 |
80 | PASK | 0.71109579 |
81 | EPHA3 | 0.70269890 |
82 | CSF1R | 0.69987357 |
83 | FLT3 | 0.69671036 |
84 | CHUK | 0.69163585 |
85 | CAMK1G | 0.66629618 |
86 | FGFR1 | 0.64736778 |
87 | NME2 | 0.64509016 |
88 | NEK9 | 0.61030316 |
89 | KIT | 0.59297084 |
90 | KSR2 | 0.59096929 |
91 | CLK1 | 0.59040114 |
92 | ARAF | 0.58553845 |
93 | HCK | 0.57403259 |
94 | TYRO3 | 0.57139723 |
95 | FER | 0.56585080 |
96 | MAP2K2 | 0.55879825 |
97 | MST4 | 0.55601304 |
98 | RPS6KB2 | 0.54709507 |
99 | PRKD3 | 0.54141342 |
100 | MAPKAPK3 | 0.53525041 |
101 | KSR1 | 0.53494900 |
102 | PIM2 | 0.52487853 |
103 | BTK | 0.52235208 |
104 | LMTK2 | 0.51493343 |
105 | MELK | 0.51461929 |
106 | MAP3K7 | 0.50795605 |
107 | MAP2K1 | 0.49827086 |
108 | WNK4 | 0.49733118 |
109 | MARK3 | 0.49642222 |
110 | LCK | 0.49586447 |
111 | HIPK2 | 0.48955213 |
112 | NLK | 0.48616852 |
113 | MAP3K1 | 0.47425500 |
114 | PIM1 | 0.47347840 |
115 | PRKG2 | 0.47096146 |
116 | ILK | 0.45917101 |
117 | WNK1 | 0.45878636 |
118 | ALK | 0.44723031 |
119 | CDK9 | 0.44722352 |
120 | MAPK7 | 0.44487769 |
121 | MAPKAPK2 | 0.43422613 |
122 | PDPK1 | 0.43193219 |
123 | EPHA2 | 0.43068657 |
124 | RPS6KL1 | 0.42783418 |
125 | RPS6KC1 | 0.42783418 |
126 | ERBB2 | 0.41978737 |
127 | CDK4 | 0.40949973 |
128 | MAPK11 | 0.40907071 |
129 | STK4 | 0.40707033 |
130 | ROCK1 | 0.39748405 |
131 | MYLK | 0.39704968 |
132 | INSR | 0.39488728 |
133 | GSK3A | 0.39290408 |
134 | PRKD2 | 0.39102341 |
135 | PAK1 | 0.38149265 |
136 | PRKD1 | 0.36947660 |
137 | PIK3CA | 0.36487504 |
138 | PDK3 | 0.36389543 |
139 | MARK2 | 0.36235480 |
140 | PIK3CG | 0.35335932 |
141 | ADRBK1 | 0.32526262 |
142 | IRAK4 | 0.29733259 |
143 | DAPK3 | 0.29649553 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ECM-receptor interaction_Homo sapiens_hsa04512 | 2.39218700 |
2 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 2.10731821 |
3 | Focal adhesion_Homo sapiens_hsa04510 | 2.10189517 |
4 | Small cell lung cancer_Homo sapiens_hsa05222 | 2.07804369 |
5 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.99224784 |
6 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.90126547 |
7 | Adherens junction_Homo sapiens_hsa04520 | 1.74103755 |
8 | Bladder cancer_Homo sapiens_hsa05219 | 1.73467403 |
9 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.67895655 |
10 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.66197866 |
11 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.65254035 |
12 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.62009462 |
13 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.57260586 |
14 | Amoebiasis_Homo sapiens_hsa05146 | 1.56405788 |
15 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.54974021 |
16 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.50449591 |
17 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.45198133 |
18 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.41904100 |
19 | Renin-angiotensin system_Homo sapiens_hsa04614 | 1.38858816 |
20 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.36719564 |
21 | Viral myocarditis_Homo sapiens_hsa05416 | 1.34060699 |
22 | Leishmaniasis_Homo sapiens_hsa05140 | 1.32144261 |
23 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.30070901 |
24 | Platelet activation_Homo sapiens_hsa04611 | 1.24220729 |
25 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.23843553 |
26 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.21055162 |
27 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.20238330 |
28 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.19235358 |
29 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.16713287 |
30 | Measles_Homo sapiens_hsa05162 | 1.14711987 |
31 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.13700876 |
32 | Prostate cancer_Homo sapiens_hsa05215 | 1.12706637 |
33 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.12454387 |
34 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.12205992 |
35 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.11826010 |
36 | HTLV-I infection_Homo sapiens_hsa05166 | 1.11107622 |
37 | Hepatitis B_Homo sapiens_hsa05161 | 1.10403130 |
38 | Apoptosis_Homo sapiens_hsa04210 | 1.09612084 |
39 | Shigellosis_Homo sapiens_hsa05131 | 1.08892155 |
40 | Malaria_Homo sapiens_hsa05144 | 1.07714235 |
41 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.04693302 |
42 | Endometrial cancer_Homo sapiens_hsa05213 | 1.04651618 |
43 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.04266501 |
44 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 1.03858321 |
45 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.02843184 |
46 | Insulin resistance_Homo sapiens_hsa04931 | 1.02313218 |
47 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.02286460 |
48 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.00669796 |
49 | Melanoma_Homo sapiens_hsa05218 | 1.00146006 |
50 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.98144976 |
51 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.97615077 |
52 | Other glycan degradation_Homo sapiens_hsa00511 | 0.97191628 |
53 | Colorectal cancer_Homo sapiens_hsa05210 | 0.96739189 |
54 | Lysosome_Homo sapiens_hsa04142 | 0.96509179 |
55 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.94419827 |
56 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.92855472 |
57 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.92369830 |
58 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.91492416 |
59 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.88850983 |
60 | Glioma_Homo sapiens_hsa05214 | 0.88770307 |
61 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.88432591 |
62 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.87742988 |
63 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.86988716 |
64 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.86887141 |
65 | * Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.86560457 |
66 | Legionellosis_Homo sapiens_hsa05134 | 0.86092784 |
67 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.85361251 |
68 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.84681945 |
69 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.84668239 |
70 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.84229735 |
71 | Endocytosis_Homo sapiens_hsa04144 | 0.83888524 |
72 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.83844258 |
73 | Pathways in cancer_Homo sapiens_hsa05200 | 0.83519221 |
74 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.81562297 |
75 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.81126797 |
76 | Galactose metabolism_Homo sapiens_hsa00052 | 0.81052962 |
77 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.80687390 |
78 | Salmonella infection_Homo sapiens_hsa05132 | 0.79417925 |
79 | Prion diseases_Homo sapiens_hsa05020 | 0.78980741 |
80 | Thyroid cancer_Homo sapiens_hsa05216 | 0.76467864 |
81 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.75935287 |
82 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.75562077 |
83 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.74931667 |
84 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.74688077 |
85 | Lysine degradation_Homo sapiens_hsa00310 | 0.73825531 |
86 | Influenza A_Homo sapiens_hsa05164 | 0.73235781 |
87 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.72041779 |
88 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.71434972 |
89 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.71398908 |
90 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.69787224 |
91 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.69472340 |
92 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.69276716 |
93 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.68986446 |
94 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.67210109 |
95 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.67196579 |
96 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.66905216 |
97 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.66691364 |
98 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.66667212 |
99 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.66564007 |
100 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.65989762 |
101 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.65330544 |
102 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.65087021 |
103 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.65075247 |
104 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.64915688 |
105 | Hepatitis C_Homo sapiens_hsa05160 | 0.63958246 |
106 | Tuberculosis_Homo sapiens_hsa05152 | 0.63634677 |
107 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.63141590 |
108 | Phagosome_Homo sapiens_hsa04145 | 0.62340685 |
109 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.62319687 |
110 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.61961940 |
111 | Tight junction_Homo sapiens_hsa04530 | 0.61689800 |
112 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.61676950 |
113 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.59959052 |
114 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.59014357 |
115 | Gap junction_Homo sapiens_hsa04540 | 0.58839552 |
116 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.56675241 |
117 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.56652459 |
118 | Axon guidance_Homo sapiens_hsa04360 | 0.54045213 |
119 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.54002336 |
120 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.52775906 |
121 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.52691905 |