GALNT10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the GalNAc polypeptide N-acetylgalactosaminyltransferases. These enzymes catalyze the first step in the synthesis of mucin-type oligosaccharides. These proteins transfer GalNAc from UDP-GalNAc to either serine or threonine residues of polypeptide acceptors. The protein encoded by this locus may have increased catalytic activity toward glycosylated peptides compared to activity toward non-glycosylated peptides. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1glomerular visceral epithelial cell development (GO:0072015)6.44897956
2glomerular epithelial cell development (GO:0072310)5.80097504
3glomerular basement membrane development (GO:0032836)5.11805485
4COPI coating of Golgi vesicle (GO:0048205)4.17695501
5Golgi transport vesicle coating (GO:0048200)4.17695501
6positive regulation of histone deacetylation (GO:0031065)4.14082448
7antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.11320320
8antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.11320320
9cell adhesion mediated by integrin (GO:0033627)3.91043147
10protein heterotrimerization (GO:0070208)3.81208042
11mesodermal cell differentiation (GO:0048333)3.60182343
12apoptotic cell clearance (GO:0043277)3.58717954
13endothelial cell chemotaxis (GO:0035767)3.56735428
14sequestering of extracellular ligand from receptor (GO:0035581)3.51800981
15hypotonic response (GO:0006971)3.49474749
16barbed-end actin filament capping (GO:0051016)3.47311406
17antigen processing and presentation of endogenous antigen (GO:0019883)3.45628974
18hemidesmosome assembly (GO:0031581)3.43981736
19endodermal cell differentiation (GO:0035987)3.43925219
20regulation of gamma-delta T cell differentiation (GO:0045586)3.39924412
21vascular endothelial growth factor signaling pathway (GO:0038084)3.37582730
22positive regulation of osteoblast proliferation (GO:0033690)3.35967046
23type B pancreatic cell proliferation (GO:0044342)3.33989522
24membrane raft organization (GO:0031579)3.32974877
25skin morphogenesis (GO:0043589)3.32851821
26epithelial cell-cell adhesion (GO:0090136)3.25125612
27positive thymic T cell selection (GO:0045059)3.24919773
28protein localization to endosome (GO:0036010)3.24804482
29positive regulation of p38MAPK cascade (GO:1900745)3.16371873
30cell-substrate adherens junction assembly (GO:0007045)3.15798352
31focal adhesion assembly (GO:0048041)3.15798352
32bone trabecula formation (GO:0060346)3.15498132
33negative regulation of fatty acid transport (GO:2000192)3.14819602
34dichotomous subdivision of an epithelial terminal unit (GO:0060600)3.14169104
35cell migration involved in sprouting angiogenesis (GO:0002042)3.13219098
36collagen fibril organization (GO:0030199)3.12804007
37negative regulation of chondrocyte differentiation (GO:0032331)3.12194304
38adherens junction assembly (GO:0034333)3.11765078
39positive regulation of gamma-delta T cell activation (GO:0046645)3.09626166
40membrane protein ectodomain proteolysis (GO:0006509)3.09085672
41regulation of extracellular matrix disassembly (GO:0010715)3.08281753
42actin filament depolymerization (GO:0030042)3.07815120
43wound healing, spreading of cells (GO:0044319)3.05364521
44protein hydroxylation (GO:0018126)3.04781052
45positive regulation of protein deacetylation (GO:0090312)3.04599589
46regulation of apoptotic process involved in morphogenesis (GO:1902337)3.04056830
47activation of signaling protein activity involved in unfolded protein response (GO:0006987)3.03724628
48extracellular fibril organization (GO:0043206)3.00971397
49stress fiber assembly (GO:0043149)2.99560916
50positive regulation of nuclease activity (GO:0032075)2.97431451
51heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.97235348
52peptidyl-proline hydroxylation (GO:0019511)2.97125819
53regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.94799301
54regulation of gamma-delta T cell activation (GO:0046643)2.93733434
55positive regulation of blood vessel endothelial cell migration (GO:0043536)2.93731655
56positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.93728663
57response to laminar fluid shear stress (GO:0034616)2.92121977
58vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.90962120
59negative regulation of anoikis (GO:2000811)2.90524095
60positive regulation of endothelial cell apoptotic process (GO:2000353)2.88718437
61fibril organization (GO:0097435)2.87139142
62iron ion import (GO:0097286)2.86812361
63positive regulation of extracellular matrix organization (GO:1903055)2.86721725
64regulation of transforming growth factor beta2 production (GO:0032909)2.85486157
65blood vessel endothelial cell migration (GO:0043534)2.85311667
66positive regulation of cell adhesion mediated by integrin (GO:0033630)2.83929614
67cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.83848899
68cytoskeletal anchoring at plasma membrane (GO:0007016)2.83595837
69SMAD protein complex assembly (GO:0007183)2.82503367
70negative regulation of erythrocyte differentiation (GO:0045647)2.81928883
71mannose metabolic process (GO:0006013)2.80501549
72natural killer cell differentiation (GO:0001779)2.78154197
73hepatocyte apoptotic process (GO:0097284)2.74887807
74substrate-dependent cell migration (GO:0006929)2.73009185
75extracellular matrix assembly (GO:0085029)2.71461538
76chondrocyte proliferation (GO:0035988)2.71232382
77regulation of nuclease activity (GO:0032069)2.68058633
78cortical actin cytoskeleton organization (GO:0030866)2.67380188
79maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.67036457
80endothelial cell morphogenesis (GO:0001886)2.66514352
81kidney mesenchyme development (GO:0072074)2.66332052
82wound healing, spreading of epidermal cells (GO:0035313)2.66216000
83regulation of early endosome to late endosome transport (GO:2000641)2.65296920
84regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.65090411
85planar cell polarity pathway involved in neural tube closure (GO:0090179)2.64954786
86chondrocyte development (GO:0002063)2.64265762
87retina vasculature morphogenesis in camera-type eye (GO:0061299)2.63451870
88positive regulation of natural killer cell differentiation (GO:0032825)2.62934671
89germ cell migration (GO:0008354)2.62717168
90regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.62553161
91positive regulation of endothelial cell migration (GO:0010595)2.62133988
92regulation of osteoblast proliferation (GO:0033688)2.61150977
93endoplasmic reticulum unfolded protein response (GO:0030968)2.60603200
94positive regulation of epithelial to mesenchymal transition (GO:0010718)2.59849236
95semaphorin-plexin signaling pathway (GO:0071526)2.58793355
96negative regulation of protein localization to plasma membrane (GO:1903077)2.58071566
97regulation of p38MAPK cascade (GO:1900744)2.57121803
98positive regulation of receptor recycling (GO:0001921)2.57099091
99chondroitin sulfate biosynthetic process (GO:0030206)2.57066851
100regulation of interleukin-12 biosynthetic process (GO:0045075)2.56481971
101vesicle coating (GO:0006901)2.56429074
102negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394)2.55900148
103positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241)2.53749941
104response to fluid shear stress (GO:0034405)2.53391733
105protein targeting to plasma membrane (GO:0072661)2.53065414
106multicellular organismal macromolecule metabolic process (GO:0044259)2.52584188
107positive regulation of epithelial cell migration (GO:0010634)2.52516574
108pericardium development (GO:0060039)2.52026938
109substrate adhesion-dependent cell spreading (GO:0034446)2.51517149
110multicellular organismal catabolic process (GO:0044243)2.51372590
111regulation of T cell tolerance induction (GO:0002664)2.50808471
112muscle cell migration (GO:0014812)2.50548741
113pathway-restricted SMAD protein phosphorylation (GO:0060389)2.50227827
114growth hormone receptor signaling pathway (GO:0060396)2.49785537
115COPII vesicle coating (GO:0048208)2.49704747
116antigen processing and presentation via MHC class Ib (GO:0002475)2.49684324
117cellular response to unfolded protein (GO:0034620)2.49073587
118hyaluronan catabolic process (GO:0030214)2.48707842
119thymic T cell selection (GO:0045061)2.48659318
120pinocytosis (GO:0006907)2.47296800
121regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.46796362
122collagen metabolic process (GO:0032963)2.46041753
123regulation of anoikis (GO:2000209)2.43784197
124antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.42612984
125collagen catabolic process (GO:0030574)2.42584287
126negative regulation of cell size (GO:0045792)2.41976123
127maternal placenta development (GO:0001893)2.40366769
128NLS-bearing protein import into nucleus (GO:0006607)2.39938935
129axon extension involved in axon guidance (GO:0048846)2.39187461
130neuron projection extension involved in neuron projection guidance (GO:1902284)2.39187461
131negative regulation of smooth muscle cell migration (GO:0014912)2.38820773
132cellular response to vitamin (GO:0071295)2.37355135
133integrin-mediated signaling pathway (GO:0007229)2.37328222
134multicellular organismal metabolic process (GO:0044236)2.37019324
135cell-substrate junction assembly (GO:0007044)2.37002385
136positive T cell selection (GO:0043368)2.35906230
137retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.35801071
138cellular response to vitamin D (GO:0071305)2.35720187
139endothelial tube morphogenesis (GO:0061154)2.35450339
140morphogenesis of an endothelium (GO:0003159)2.35450339
141protein retention in ER lumen (GO:0006621)2.35437499
142positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.35392473
143JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.34525889
144positive regulation of tolerance induction (GO:0002645)2.34269286
145positive regulation of transforming growth factor beta receptor signaling pathway (GO:0030511)2.33579984
146ER-nucleus signaling pathway (GO:0006984)2.33451315
147basement membrane organization (GO:0071711)2.33423535
148endothelial cell migration (GO:0043542)2.31591155
149hippo signaling (GO:0035329)2.31518137
150cellular response to growth hormone stimulus (GO:0071378)2.31161575
151receptor catabolic process (GO:0032801)2.29467251
152positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.27402156
153extracellular matrix disassembly (GO:0022617)2.27138462
154negative T cell selection (GO:0043383)2.25811538
155glomerulus development (GO:0032835)2.25719653
156regulation of tight junction assembly (GO:2000810)2.25233558
157insulin-like growth factor receptor signaling pathway (GO:0048009)2.25131361

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.87358540
2TP63_17297297_ChIP-ChIP_HaCaT_Human3.68518229
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.21158225
4FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.07435868
5MYC_22102868_ChIP-Seq_BL_Human2.86737971
6TRIM28_21343339_ChIP-Seq_HEK293_Human2.68141670
7SMAD_19615063_ChIP-ChIP_OVARY_Human2.66552369
8STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.64617355
9RARG_19884340_ChIP-ChIP_MEFs_Mouse2.55561945
10CLOCK_20551151_ChIP-Seq_293T_Human2.49304494
11SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.31319951
12PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.28269447
13VDR_21846776_ChIP-Seq_THP-1_Human2.28073933
14ELK3_25401928_ChIP-Seq_HUVEC_Human2.27404504
15FOXM1_23109430_ChIP-Seq_U2OS_Human2.24696569
16TCF7_22412390_ChIP-Seq_EML_Mouse2.16364346
17STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.12675771
18KDM2B_26808549_Chip-Seq_DND41_Human2.12493926
19* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.08258660
20TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.07188933
21KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.06457584
22KDM2B_26808549_Chip-Seq_SUP-B15_Human2.00091522
23STAT6_21828071_ChIP-Seq_BEAS2B_Human1.96501375
24KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.96079371
25MAF_26560356_Chip-Seq_TH1_Human1.92530844
26KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.90451231
27UTX_26944678_Chip-Seq_JUKART_Human1.87883393
28BRD4_27068464_Chip-Seq_AML-cells_Mouse1.76032894
29TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.75669385
30HIF1A_21447827_ChIP-Seq_MCF-7_Human1.70714752
31LXR_22292898_ChIP-Seq_THP-1_Human1.69511920
32IRF8_22096565_ChIP-ChIP_GC-B_Human1.67179898
33* CJUN_26792858_Chip-Seq_BT549_Human1.66732436
34MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.61612664
35SOX9_24532713_ChIP-Seq_HFSC_Mouse1.59006713
36VDR_24763502_ChIP-Seq_THP-1_Human1.58133086
37ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.56322364
38NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.55914904
39MYB_26560356_Chip-Seq_TH2_Human1.55838894
40MYB_21317192_ChIP-Seq_ERMYB_Mouse1.55565064
41P300_27058665_Chip-Seq_ZR-75-30cells_Human1.54123817
42RACK7_27058665_Chip-Seq_MCF-7_Human1.54060567
43SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.53334797
44FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.52289151
45TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.51989267
46KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.50781226
47FOXO3_23340844_ChIP-Seq_DLD1_Human1.49967723
48ATF3_27146783_Chip-Seq_COLON_Human1.48715009
49E2F7_22180533_ChIP-Seq_HELA_Human1.46913668
50* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.46037881
51NCOR1_26117541_ChIP-Seq_K562_Human1.45683127
52NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.44779965
53ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.44218810
54* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.43598771
55STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.42839201
56E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.41729744
57RUNX_20019798_ChIP-Seq_JUKART_Human1.41721392
58CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.41268307
59ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.41176858
60RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.40338667
61ESR2_21235772_ChIP-Seq_MCF-7_Human1.39219606
62GATA1_19941826_ChIP-Seq_K562_Human1.37671270
63KDM2B_26808549_Chip-Seq_JURKAT_Human1.36985985
64Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.35545602
65ESR1_20079471_ChIP-ChIP_T-47D_Human1.35174324
66RUNX1_22412390_ChIP-Seq_EML_Mouse1.34865686
67* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.34815769
68FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.34022841
69EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.33070036
70JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.31870242
71MYB_26560356_Chip-Seq_TH1_Human1.30207167
72ZNF263_19887448_ChIP-Seq_K562_Human1.30104591
73IRF8_27001747_Chip-Seq_BMDM_Mouse1.28626929
74* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.28504870
75DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.28076467
76SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.27686372
77ESR1_21235772_ChIP-Seq_MCF-7_Human1.26940980
78THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.25976787
79NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.23183050
80GATA6_25053715_ChIP-Seq_YYC3_Human1.22133291
81IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.21673584
82* PPAR_26484153_Chip-Seq_NCI-H1993_Human1.21364709
83SPI1_23127762_ChIP-Seq_K562_Human1.20614699
84RUNX1_27514584_Chip-Seq_MCF-7_Human1.18319439
85* SOX2_27498859_Chip-Seq_STOMACH_Mouse1.17781666
86WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.16524651
87KDM2B_26808549_Chip-Seq_K562_Human1.16414915
88UBF1/2_26484160_Chip-Seq_HMECs_Human1.15721722
89RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.15024906
90SCL_19346495_ChIP-Seq_HPC-7_Human1.14742670
91NFIB_24661679_ChIP-Seq_LUNG_Mouse1.14395184
92NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.14381283
93GATA1_22383799_ChIP-Seq_G1ME_Mouse1.12759425
94* GATA2_19941826_ChIP-Seq_K562_Human1.11863342
95SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.11679874
96SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.11679874
97CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.09983211
98EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.09196332
99TBX20_22328084_ChIP-Seq_HEART_Mouse1.08273170
100TBX20_22080862_ChIP-Seq_HEART_Mouse1.08273170
101TP53_22127205_ChIP-Seq_IMR90_Human1.07689874
102* TP53_23651856_ChIP-Seq_MEFs_Mouse1.07370068
103SALL4_18804426_ChIP-ChIP_XEN_Mouse1.07175114
104MAF_26560356_Chip-Seq_TH2_Human1.06040791
105* BRD4_25478319_ChIP-Seq_HGPS_Human1.05972164
106DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.05117341
107* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.03993613
108ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.03855822
109ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.03402036
110FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.03371748
111EP300_21415370_ChIP-Seq_HL-1_Mouse1.02841169
112CTNNB1_20460455_ChIP-Seq_HCT116_Human1.02511854
113HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.01086582
114* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.00747664
115WT1_19549856_ChIP-ChIP_CCG9911_Human1.00380591
116UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.99895204
117JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.98419172
118P63_26484246_Chip-Seq_KERATINOCYTES_Human0.97701890
119TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.97179572
120VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.96766245
121* SOX2_20726797_ChIP-Seq_SW620_Human0.96718718
122ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.96454020
123TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.95797690
124* SMC1_22415368_ChIP-Seq_MEFs_Mouse0.95683410
125CTCF_27219007_Chip-Seq_ERYTHROID_Human0.95127918
126GATA2_21666600_ChIP-Seq_HMVEC_Human0.92984211
127CREB1_26743006_Chip-Seq_LNCaP_Human0.92947183

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen4.03811128
2MP0003705_abnormal_hypodermis_morpholog3.92913528
3MP0003300_gastrointestinal_ulcer3.31394623
4MP0010352_gastrointestinal_tract_polyps2.96754708
5MP0006054_spinal_hemorrhage2.51175314
6MP0003279_aneurysm2.43899823
7MP0003950_abnormal_plasma_membrane2.28301037
8MP0005275_abnormal_skin_tensile2.22633544
9MP0003566_abnormal_cell_adhesion2.19448141
10MP0005623_abnormal_meninges_morphology2.11511660
11MP0005503_abnormal_tendon_morphology2.03325972
12MP0005076_abnormal_cell_differentiation2.00252943
13MP0004272_abnormal_basement_membrane1.86520186
14MP0009278_abnormal_bone_marrow1.84885744
15MP0003091_abnormal_cell_migration1.83640376
16MP0003303_peritoneal_inflammation1.79113582
17MP0005023_abnormal_wound_healing1.79061067
18MP0002166_altered_tumor_susceptibility1.73064956
19MP0003191_abnormal_cellular_cholesterol1.71996869
20MP0009384_cardiac_valve_regurgitation1.70799118
21MP0001542_abnormal_bone_strength1.58372224
22MP0001958_emphysema1.57110379
23MP0002877_abnormal_melanocyte_morpholog1.55894233
24MP0000685_abnormal_immune_system1.55784329
25MP0003283_abnormal_digestive_organ1.55045391
26MP0010234_abnormal_vibrissa_follicle1.54120615
27MP0000733_abnormal_muscle_development1.47131890
28MP0004808_abnormal_hematopoietic_stem1.45400814
29MP0004185_abnormal_adipocyte_glucose1.41713500
30MP0000537_abnormal_urethra_morphology1.39358652
31MP0001348_abnormal_lacrimal_gland1.37160445
32MP0000858_altered_metastatic_potential1.35313236
33MP0004947_skin_inflammation1.34749867
34MP0005257_abnormal_intraocular_pressure1.31284909
35MP0010307_abnormal_tumor_latency1.29720445
36MP0009053_abnormal_anal_canal1.28297773
37MP0002933_joint_inflammation1.28064381
38MP0005451_abnormal_body_composition1.26886599
39MP0004858_abnormal_nervous_system1.24812462
40MP0004233_abnormal_muscle_weight1.24111471
41MP0002060_abnormal_skin_morphology1.21758646
42MP0003436_decreased_susceptibility_to1.18744292
43MP0005164_abnormal_response_to1.18145439
44MP0002896_abnormal_bone_mineralization1.17835301
45MP0002006_tumorigenesis1.17760760
46MP0001533_abnormal_skeleton_physiology1.17473993
47MP0001873_stomach_inflammation1.17350376
48MP0001545_abnormal_hematopoietic_system1.16435415
49MP0005397_hematopoietic_system_phenotyp1.16435415
50MP0008961_abnormal_basal_metabolism1.14628533
51MP0010155_abnormal_intestine_physiology1.14491516
52MP0001849_ear_inflammation1.13966715
53MP0003763_abnormal_thymus_physiology1.12091991
54MP0010368_abnormal_lymphatic_system1.11083968
55MP0003045_fibrosis1.10525578
56MP0002998_abnormal_bone_remodeling1.09846887
57MP0000767_abnormal_smooth_muscle1.09250553
58MP0009333_abnormal_splenocyte_physiolog1.08186722
59MP0009780_abnormal_chondrocyte_physiolo1.07947015
60MP0002295_abnormal_pulmonary_circulatio1.07205490
61MP0005508_abnormal_skeleton_morphology1.06972500
62MP0000490_abnormal_crypts_of1.04219177
63MP0003828_pulmonary_edema1.04165809
64MP0003866_abnormal_defecation1.03665337
65MP0001915_intracranial_hemorrhage1.00414342
66MP0001879_abnormal_lymphatic_vessel0.99616082
67MP0000477_abnormal_intestine_morphology0.99513154
68MP0001243_abnormal_dermal_layer0.99189218
69MP0005390_skeleton_phenotype0.98113724
70MP0002396_abnormal_hematopoietic_system0.97148599
71MP0006082_CNS_inflammation0.96882757
72MP0005464_abnormal_platelet_physiology0.96716708
73MP0003448_altered_tumor_morphology0.96631694
74MP0003656_abnormal_erythrocyte_physiolo0.96037755
75MP0010030_abnormal_orbit_morphology0.94344683
76MP0005595_abnormal_vascular_smooth0.93888083
77MP0000751_myopathy0.93393153
78MP0005058_abnormal_lysosome_morphology0.93290390
79MP0005165_increased_susceptibility_to0.92680296
80MP0005621_abnormal_cell_physiology0.91094259
81MP0000762_abnormal_tongue_morphology0.90924287
82MP0000003_abnormal_adipose_tissue0.90902485
83MP0002405_respiratory_system_inflammati0.90387260
84MP0005197_abnormal_uvea_morphology0.89585721
85MP0003795_abnormal_bone_structure0.88726944
86MP0005375_adipose_tissue_phenotype0.87863838
87MP0005409_darkened_coat_color0.87853218
88MP0002168_other_aberrant_phenotype0.87088242
89MP0002135_abnormal_kidney_morphology0.86942012
90MP0003115_abnormal_respiratory_system0.86020325
91MP0002398_abnormal_bone_marrow0.85845490
92MP0003453_abnormal_keratinocyte_physiol0.85177142
93MP0005666_abnormal_adipose_tissue0.83389535
94MP0002128_abnormal_blood_circulation0.83332787
95MP0001614_abnormal_blood_vessel0.83293878
96MP0003941_abnormal_skin_development0.83243254
97MP0002089_abnormal_postnatal_growth/wei0.83072839
98MP0002925_abnormal_cardiovascular_devel0.82484878
99MP0000428_abnormal_craniofacial_morphol0.81241897
100MP0000013_abnormal_adipose_tissue0.80904370
101MP0002452_abnormal_antigen_presenting0.80708983
102MP0000465_gastrointestinal_hemorrhage0.80401947
103MP0002113_abnormal_skeleton_development0.80280180
104MP0004134_abnormal_chest_morphology0.79457170
105MP0001790_abnormal_immune_system0.79241120
106MP0005387_immune_system_phenotype0.79241120
107MP0002136_abnormal_kidney_physiology0.79027985
108MP0008260_abnormal_autophagy0.78983497
109MP0005501_abnormal_skin_physiology0.78011569
110MP0000703_abnormal_thymus_morphology0.77747943
111MP0009840_abnormal_foam_cell0.76283942
112MP0009250_abnormal_appendicular_skeleto0.76219247
113MP0002722_abnormal_immune_system0.75990967
114MP0000534_abnormal_ureter_morphology0.74525176
115MP0001819_abnormal_immune_cell0.74280747
116MP0002420_abnormal_adaptive_immunity0.74239876
117MP0005388_respiratory_system_phenotype0.73992120
118MP0002133_abnormal_respiratory_system0.73992120
119MP0003942_abnormal_urinary_system0.73400272
120MP0005000_abnormal_immune_tolerance0.72419637
121MP0000759_abnormal_skeletal_muscle0.71984780
122MP0003385_abnormal_body_wall0.71709828
123MP0001175_abnormal_lung_morphology0.71380661
124MP0003252_abnormal_bile_duct0.70902544
125MP0005083_abnormal_biliary_tract0.70897532
126MP0000462_abnormal_digestive_system0.70858651
127MP0001800_abnormal_humoral_immune0.70004473
128MP0000163_abnormal_cartilage_morphology0.69748008
129MP0002932_abnormal_joint_morphology0.69380211
130MP0005193_abnormal_anterior_eye0.69336899
131MP0004084_abnormal_cardiac_muscle0.69267977
132MP0009643_abnormal_urine_homeostasis0.69148354
133MP0004883_abnormal_blood_vessel0.68720744
134MP0001299_abnormal_eye_distance/0.68647342
135MP0000249_abnormal_blood_vessel0.67128971
136MP0002108_abnormal_muscle_morphology0.65260134
137MP0004782_abnormal_surfactant_physiolog0.65060036
138MP0000627_abnormal_mammary_gland0.63622334
139MP0000343_altered_response_to0.61660049
140MP0004510_myositis0.61316132

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)5.17814192
2Premature rupture of membranes (HP:0001788)4.70230900
3Cerebral aneurysm (HP:0004944)4.48646097
4Aortic aneurysm (HP:0004942)4.31276018
5Aortic dissection (HP:0002647)4.06570378
6Shallow orbits (HP:0000586)3.59870774
7Mesangial abnormality (HP:0001966)3.51910527
8Ankle contracture (HP:0006466)3.46025700
9Peritonitis (HP:0002586)3.27641667
10Dilatation of the ascending aorta (HP:0005111)3.22325950
11Mitral valve prolapse (HP:0001634)3.16668915
12Genu recurvatum (HP:0002816)3.03316266
13Focal segmental glomerulosclerosis (HP:0000097)2.98679230
14Atrophic scars (HP:0001075)2.95035979
15Short nail (HP:0001799)2.89473726
16Broad metatarsal (HP:0001783)2.88703372
17Aneurysm (HP:0002617)2.86592458
18Fragile skin (HP:0001030)2.75749569
19Abnormal albumin level (HP:0012116)2.73680111
20Hypoalbuminemia (HP:0003073)2.73680111
21Broad face (HP:0000283)2.70332241
22Bladder diverticulum (HP:0000015)2.67169173
23Cervical subluxation (HP:0003308)2.63199391
24Hematochezia (HP:0002573)2.62634784
25Aortic regurgitation (HP:0001659)2.62629464
26Increased density of long bones (HP:0006392)2.60421113
27Mitral stenosis (HP:0001718)2.48354219
28Soft skin (HP:0000977)2.42673178
29Autoimmune thrombocytopenia (HP:0001973)2.41029623
30Absent frontal sinuses (HP:0002688)2.40797843
31Blue sclerae (HP:0000592)2.37656137
32Bowel diverticulosis (HP:0005222)2.37132029
33Abnormality of the nasal mucosa (HP:0000433)2.36702325
34Nasal polyposis (HP:0100582)2.33709069
35Nonimmune hydrops fetalis (HP:0001790)2.32681136
36Follicular hyperkeratosis (HP:0007502)2.31001296
37Osteolytic defects of the phalanges of the hand (HP:0009771)2.29299169
38Osteolytic defects of the hand bones (HP:0009699)2.29299169
39Abnormality of the peritoneum (HP:0002585)2.27890384
40Syringomyelia (HP:0003396)2.26786146
41Spinal cord lesions (HP:0100561)2.26786146
42Thin bony cortex (HP:0002753)2.26192585
43Aortic valve stenosis (HP:0001650)2.23227396
44Vascular tortuosity (HP:0004948)2.21813565
45Arterial tortuosity (HP:0005116)2.21494476
46Distal lower limb amyotrophy (HP:0008944)2.19410127
47Nephritis (HP:0000123)2.14997028
48Vertebral compression fractures (HP:0002953)2.13074025
49Overgrowth (HP:0001548)2.10644081
50Ulnar bowing (HP:0003031)2.09818830
51Rectal prolapse (HP:0002035)2.08630259
52Joint stiffness (HP:0001387)2.07281611
53Glomerulosclerosis (HP:0000096)2.06600004
54Cardiovascular calcification (HP:0011915)2.06450820
55Disproportionate tall stature (HP:0001519)2.06390587
56Deviation of the hallux (HP:0010051)2.06051098
57Distal upper limb amyotrophy (HP:0007149)2.05497068
58Upper limb amyotrophy (HP:0009129)2.05497068
59Hyperacusis (HP:0010780)2.04029451
60Severe short stature (HP:0003510)2.03562468
61Increased variability in muscle fiber diameter (HP:0003557)2.02442318
62Increased connective tissue (HP:0009025)2.02020613
63Wormian bones (HP:0002645)2.00562431
64Hallux valgus (HP:0001822)2.00488225
65Short 4th metacarpal (HP:0010044)2.00409355
66Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.00409355
67Radial bowing (HP:0002986)1.99310573
68Hand muscle atrophy (HP:0009130)1.98116308
69Persistence of primary teeth (HP:0006335)1.96484350
70Abnormality of the acetabulum (HP:0003170)1.95833636
71Bicuspid aortic valve (HP:0001647)1.95148311
72Coxa vara (HP:0002812)1.93931238
73Striae distensae (HP:0001065)1.93915194
74Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.93680108
75Slender build (HP:0001533)1.90011867
76Interstitial pulmonary disease (HP:0006530)1.89576079
77Abnormal delivery (HP:0001787)1.88776707
78Long toe (HP:0010511)1.88434846
79Camptodactyly of toe (HP:0001836)1.86640090
80Subacute progressive viral hepatitis (HP:0006572)1.86447743
81Increased mean platelet volume (HP:0011877)1.85558033
82Abnormality of carpal bone ossification (HP:0006257)1.83585141
83Ovoid vertebral bodies (HP:0003300)1.83449827
84Lymphangioma (HP:0100764)1.83402045
85Spinal cord compression (HP:0002176)1.82671169
86Ectopia lentis (HP:0001083)1.82540918
87Mildly elevated creatine phosphokinase (HP:0008180)1.82392496
88Abnormality of dentin (HP:0010299)1.82121821
89Neonatal short-limb short stature (HP:0008921)1.81775393
90Delayed closure of the anterior fontanelle (HP:0001476)1.81520612
91Abnormality of skeletal muscle fiber size (HP:0012084)1.81232225
92Natal tooth (HP:0000695)1.79411689
93Abnormal platelet volume (HP:0011876)1.79039293
94Mitral regurgitation (HP:0001653)1.77978088
95Abnormal foot bone ossification (HP:0010675)1.77342372
96Flat acetabular roof (HP:0003180)1.76330716
97Tibial bowing (HP:0002982)1.76035496
98Joint laxity (HP:0001388)1.76006835
99Menorrhagia (HP:0000132)1.75789796
100Abnormality of skull ossification (HP:0002703)1.75213214
101Metaphyseal cupping (HP:0003021)1.74758089
102Abnormality of the 4th metacarpal (HP:0010012)1.74496375
103Osteoarthritis (HP:0002758)1.72601240
104Delayed cranial suture closure (HP:0000270)1.72246455
105Cupped ribs (HP:0000887)1.72093861
106Abnormality of the distal phalanx of the thumb (HP:0009617)1.72088484
107Abnormality of the fingertips (HP:0001211)1.71635040
108Difficulty climbing stairs (HP:0003551)1.71613336
109Distal lower limb muscle weakness (HP:0009053)1.71590662
110Bowing of the arm (HP:0006488)1.71374913
111Bowed forearm bones (HP:0003956)1.71374913
112Pustule (HP:0200039)1.70858215
113Hyperextensible skin (HP:0000974)1.70749827
114Mild short stature (HP:0003502)1.70468875
115Wrist flexion contracture (HP:0001239)1.70166968
116Wide anterior fontanel (HP:0000260)1.69199165
117Biconcave vertebral bodies (HP:0004586)1.67392636
118Insomnia (HP:0100785)1.65619104
119Exostoses (HP:0100777)1.65460354
120Polycythemia (HP:0001901)1.65069106
121Flat cornea (HP:0007720)1.64880210
122Generalized amyotrophy (HP:0003700)1.64752022
123Type 1 muscle fiber predominance (HP:0003803)1.64388515
124Reduced subcutaneous adipose tissue (HP:0003758)1.64082666
125Abnormality of the distal phalanges of the toes (HP:0010182)1.63934835
126Spinal rigidity (HP:0003306)1.63414839
127Abnormality of oral frenula (HP:0000190)1.62887790
128Elbow flexion contracture (HP:0002987)1.62827590
129Lumbar hyperlordosis (HP:0002938)1.62558694
130Renal duplication (HP:0000075)1.62270869
131Broad ribs (HP:0000885)1.61659927
132Abnormal ossification of hand bones (HP:0005921)1.61626189
133Glomerulonephritis (HP:0000099)1.60425857
134Enlarged penis (HP:0000040)1.60127707
135Abnormality of the calcaneus (HP:0008364)1.57808838
136Spondylolisthesis (HP:0003302)1.56974290
137Platyspondyly (HP:0000926)1.55719515
138Congenital glaucoma (HP:0001087)1.54635527

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.20027386
2PKN23.21610151
3EEF2K3.12480494
4MAP3K102.94415351
5ERN12.84164746
6MST1R2.83316611
7TTN2.65420275
8TGFBR22.30387881
9STK102.18211665
10PTK62.13242850
11PRPF4B2.08838210
12MAP4K12.07614116
13MET2.04700533
14PDGFRA2.04531991
15SIK11.99254616
16RIPK11.94758031
17IRAK31.91509952
18PAK41.84823325
19LRRK21.81938642
20SMG11.74622037
21TESK11.72867269
22NTRK11.71053211
23CDK121.70086354
24LIMK11.64947952
25SCYL21.58715335
26FGFR41.55524426
27JAK31.43163719
28LATS21.42066474
29EPHB11.40315002
30TYK21.35597777
31KDR1.32395967
32LATS11.31732144
33DDR21.31184003
34PAK21.31152403
35RPS6KA41.29685512
36MOS1.29039028
37EPHB21.26138369
38CDC42BPA1.23474317
39STK381.23177765
40MAP3K31.23074417
41ZAP701.20231837
42ERBB41.18893110
43BMX1.17783550
44JAK11.14542446
45PTK21.13763649
46ICK1.13698792
47PDGFRB1.12510289
48DYRK1B1.07344495
49GRK61.06124903
50FRK1.04281236
51TBK11.01378918
52MAP3K61.00320220
53CDK60.98826172
54NEK20.98786506
55MTOR0.98457855
56MAP2K30.97455975
57TGFBR10.96956861
58ITK0.96907518
59FGFR30.94493921
60MAP3K130.93935790
61STK30.92840469
62MAP3K20.92056371
63TRPM70.91860040
64MAP3K140.90696953
65DMPK0.89626764
66ROCK20.89126468
67CAMK1D0.88372224
68CDK80.88303882
69MAP3K80.87724501
70RPS6KA20.86403524
71TESK20.84087815
72PTK2B0.83298483
73CSK0.82498961
74TAOK20.80148191
75PRKCH0.76114909
76JAK20.75620014
77TAOK10.75573611
78EIF2AK10.74187091
79RET0.71710950
80PASK0.71109579
81EPHA30.70269890
82CSF1R0.69987357
83FLT30.69671036
84CHUK0.69163585
85CAMK1G0.66629618
86FGFR10.64736778
87NME20.64509016
88NEK90.61030316
89KIT0.59297084
90KSR20.59096929
91CLK10.59040114
92ARAF0.58553845
93HCK0.57403259
94TYRO30.57139723
95FER0.56585080
96MAP2K20.55879825
97MST40.55601304
98RPS6KB20.54709507
99PRKD30.54141342
100MAPKAPK30.53525041
101KSR10.53494900
102PIM20.52487853
103BTK0.52235208
104LMTK20.51493343
105MELK0.51461929
106MAP3K70.50795605
107MAP2K10.49827086
108WNK40.49733118
109MARK30.49642222
110LCK0.49586447
111HIPK20.48955213
112NLK0.48616852
113MAP3K10.47425500
114PIM10.47347840
115PRKG20.47096146
116ILK0.45917101
117WNK10.45878636
118ALK0.44723031
119CDK90.44722352
120MAPK70.44487769
121MAPKAPK20.43422613
122PDPK10.43193219
123EPHA20.43068657
124RPS6KL10.42783418
125RPS6KC10.42783418
126ERBB20.41978737
127CDK40.40949973
128MAPK110.40907071
129STK40.40707033
130ROCK10.39748405
131MYLK0.39704968
132INSR0.39488728
133GSK3A0.39290408
134PRKD20.39102341
135PAK10.38149265
136PRKD10.36947660
137PIK3CA0.36487504
138PDK30.36389543
139MARK20.36235480
140PIK3CG0.35335932
141ADRBK10.32526262
142IRAK40.29733259
143DAPK30.29649553

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045122.39218700
2Chronic myeloid leukemia_Homo sapiens_hsa052202.10731821
3Focal adhesion_Homo sapiens_hsa045102.10189517
4Small cell lung cancer_Homo sapiens_hsa052222.07804369
5AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.99224784
6Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.90126547
7Adherens junction_Homo sapiens_hsa045201.74103755
8Bladder cancer_Homo sapiens_hsa052191.73467403
9Pancreatic cancer_Homo sapiens_hsa052121.67895655
10Leukocyte transendothelial migration_Homo sapiens_hsa046701.66197866
11Proteoglycans in cancer_Homo sapiens_hsa052051.65254035
12Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.62009462
13Antigen processing and presentation_Homo sapiens_hsa046121.57260586
14Amoebiasis_Homo sapiens_hsa051461.56405788
15Protein digestion and absorption_Homo sapiens_hsa049741.54974021
16Toxoplasmosis_Homo sapiens_hsa051451.50449591
17Osteoclast differentiation_Homo sapiens_hsa043801.45198133
18Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.41904100
19Renin-angiotensin system_Homo sapiens_hsa046141.38858816
20Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.36719564
21Viral myocarditis_Homo sapiens_hsa054161.34060699
22Leishmaniasis_Homo sapiens_hsa051401.32144261
23Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.30070901
24Platelet activation_Homo sapiens_hsa046111.24220729
25Acute myeloid leukemia_Homo sapiens_hsa052211.23843553
26N-Glycan biosynthesis_Homo sapiens_hsa005101.21055162
27Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.20238330
28B cell receptor signaling pathway_Homo sapiens_hsa046621.19235358
29MicroRNAs in cancer_Homo sapiens_hsa052061.16713287
30Measles_Homo sapiens_hsa051621.14711987
31T cell receptor signaling pathway_Homo sapiens_hsa046601.13700876
32Prostate cancer_Homo sapiens_hsa052151.12706637
33Non-small cell lung cancer_Homo sapiens_hsa052231.12454387
34Glycosaminoglycan degradation_Homo sapiens_hsa005311.12205992
35Viral carcinogenesis_Homo sapiens_hsa052031.11826010
36HTLV-I infection_Homo sapiens_hsa051661.11107622
37Hepatitis B_Homo sapiens_hsa051611.10403130
38Apoptosis_Homo sapiens_hsa042101.09612084
39Shigellosis_Homo sapiens_hsa051311.08892155
40Malaria_Homo sapiens_hsa051441.07714235
41VEGF signaling pathway_Homo sapiens_hsa043701.04693302
42Endometrial cancer_Homo sapiens_hsa052131.04651618
43Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.04266501
44Regulation of actin cytoskeleton_Homo sapiens_hsa048101.03858321
45mTOR signaling pathway_Homo sapiens_hsa041501.02843184
46Insulin resistance_Homo sapiens_hsa049311.02313218
47Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.02286460
48Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.00669796
49Melanoma_Homo sapiens_hsa052181.00146006
50TNF signaling pathway_Homo sapiens_hsa046680.98144976
51Carbohydrate digestion and absorption_Homo sapiens_hsa049730.97615077
52Other glycan degradation_Homo sapiens_hsa005110.97191628
53Colorectal cancer_Homo sapiens_hsa052100.96739189
54Lysosome_Homo sapiens_hsa041420.96509179
55Primary immunodeficiency_Homo sapiens_hsa053400.94419827
56Notch signaling pathway_Homo sapiens_hsa043300.92855472
57NF-kappa B signaling pathway_Homo sapiens_hsa040640.92369830
58Central carbon metabolism in cancer_Homo sapiens_hsa052300.91492416
59Renal cell carcinoma_Homo sapiens_hsa052110.88850983
60Glioma_Homo sapiens_hsa052140.88770307
61Hippo signaling pathway_Homo sapiens_hsa043900.88432591
62Hematopoietic cell lineage_Homo sapiens_hsa046400.87742988
63Phospholipase D signaling pathway_Homo sapiens_hsa040720.86988716
64Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.86887141
65* Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.86560457
66Legionellosis_Homo sapiens_hsa051340.86092784
67ErbB signaling pathway_Homo sapiens_hsa040120.85361251
68Neurotrophin signaling pathway_Homo sapiens_hsa047220.84681945
69Prolactin signaling pathway_Homo sapiens_hsa049170.84668239
70p53 signaling pathway_Homo sapiens_hsa041150.84229735
71Endocytosis_Homo sapiens_hsa041440.83888524
72PI3K-Akt signaling pathway_Homo sapiens_hsa041510.83844258
73Pathways in cancer_Homo sapiens_hsa052000.83519221
74Pentose phosphate pathway_Homo sapiens_hsa000300.81562297
75Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.81126797
76Galactose metabolism_Homo sapiens_hsa000520.81052962
77Toll-like receptor signaling pathway_Homo sapiens_hsa046200.80687390
78Salmonella infection_Homo sapiens_hsa051320.79417925
79Prion diseases_Homo sapiens_hsa050200.78980741
80Thyroid cancer_Homo sapiens_hsa052160.76467864
81Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.75935287
82Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.75562077
83Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.74931667
84Jak-STAT signaling pathway_Homo sapiens_hsa046300.74688077
85Lysine degradation_Homo sapiens_hsa003100.73825531
86Influenza A_Homo sapiens_hsa051640.73235781
87HIF-1 signaling pathway_Homo sapiens_hsa040660.72041779
88Adipocytokine signaling pathway_Homo sapiens_hsa049200.71434972
89Basal cell carcinoma_Homo sapiens_hsa052170.71398908
90Sphingolipid signaling pathway_Homo sapiens_hsa040710.69787224
91TGF-beta signaling pathway_Homo sapiens_hsa043500.69472340
92Choline metabolism in cancer_Homo sapiens_hsa052310.69276716
93Dorso-ventral axis formation_Homo sapiens_hsa043200.68986446
94Caffeine metabolism_Homo sapiens_hsa002320.67210109
95Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.67196579
96Intestinal immune network for IgA production_Homo sapiens_hsa046720.66905216
97Rap1 signaling pathway_Homo sapiens_hsa040150.66691364
98Dilated cardiomyopathy_Homo sapiens_hsa054140.66667212
99Thyroid hormone signaling pathway_Homo sapiens_hsa049190.66564007
100Herpes simplex infection_Homo sapiens_hsa051680.65989762
101Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.65330544
102Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.65087021
103Chemokine signaling pathway_Homo sapiens_hsa040620.65075247
104Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.64915688
105Hepatitis C_Homo sapiens_hsa051600.63958246
106Tuberculosis_Homo sapiens_hsa051520.63634677
107Inositol phosphate metabolism_Homo sapiens_hsa005620.63141590
108Phagosome_Homo sapiens_hsa041450.62340685
109GnRH signaling pathway_Homo sapiens_hsa049120.62319687
110Vibrio cholerae infection_Homo sapiens_hsa051100.61961940
111Tight junction_Homo sapiens_hsa045300.61689800
112FoxO signaling pathway_Homo sapiens_hsa040680.61676950
113Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.59959052
114Transcriptional misregulation in cancer_Homo sapiens_hsa052020.59014357
115Gap junction_Homo sapiens_hsa045400.58839552
116Estrogen signaling pathway_Homo sapiens_hsa049150.56675241
117Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.56652459
118Axon guidance_Homo sapiens_hsa043600.54045213
119MAPK signaling pathway_Homo sapiens_hsa040100.54002336
120Longevity regulating pathway - mammal_Homo sapiens_hsa042110.52775906
121Insulin signaling pathway_Homo sapiens_hsa049100.52691905

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